@prefix biopax:  <http://www.biopax.org/release/biopax-level3.owl#> .
@prefix cito:    <http://purl.org/spar/cito/> .
@prefix dc:      <http://purl.org/dc/elements/1.1/> .
@prefix dcterms: <http://purl.org/dc/terms/> .
@prefix foaf:    <http://xmlns.com/foaf/0.1/> .
@prefix freq:    <http://purl.org/cld/freq/> .
@prefix gpml:    <http://vocabularies.wikipathways.org/gpml#> .
@prefix obo:     <http://purl.obolibrary.org/obo/> .
@prefix owl:     <http://www.w3.org/2002/07/owl#> .
@prefix pav:     <http://purl.org/pav/> .
@prefix prov:    <http://www.w3.org/ns/prov#> .
@prefix rdf:     <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix rdfs:    <http://www.w3.org/2000/01/rdf-schema#> .
@prefix skos:    <http://www.w3.org/2004/02/skos/core#> .
@prefix void:    <http://rdfs.org/ns/void#> .
@prefix wp:      <http://vocabularies.wikipathways.org/wp#> .
@prefix wprdf:   <http://rdf.wikipathways.org/> .
@prefix xsd:     <http://www.w3.org/2001/XMLSchema#> .

<http://rdf.wikipathways.org/Pathway/WP5589_r141384/Interaction/id3ffb1853/Anchor/be9a5>
        rdf:type          gpml:Anchor ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5589_r141384> , <http://rdf.wikipathways.org/Pathway/WP5589_r141384/Interaction/id3ffb1853> ;
        gpml:graphId      "be9a5" ;
        gpml:position     "0.4"^^xsd:double ;
        gpml:shape        "None" .

<http://rdf.wikipathways.org/Pathway/WP5589_r141384/Interaction/id1affc3c0/Point/49c20b845a96517f6a09ddd051cd2bea>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5589_r141384> , <http://rdf.wikipathways.org/Pathway/WP5589_r141384/Interaction/id1affc3c0> ;
        gpml:graphRef     "fb21b" ;
        gpml:relX         "-0.5"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "192.5"^^xsd:double ;
        gpml:y            "196.5"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5589_r141384/Interaction/idcfc1f0e0>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP5589_r141384> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "idcfc1f0e0" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP5589_r141384/Interaction/idcfc1f0e0/Point/1ed081588ff9b56e2381d90acbff3236> , <http://rdf.wikipathways.org/Pathway/WP5589_r141384/Interaction/idcfc1f0e0/Point/eba1de28f5174788c51a8ec899562bbf> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5589_r141384/DataNode/e19dd>
        rdf:type                 gpml:DataNode ;
        dcterms:isPartOf         <http://rdf.wikipathways.org/Pathway/WP5589_r141384> ;
        gpml:align               "Center" ;
        gpml:biopaxRef           "a42" , "f35" ;
        gpml:centerX             "358.0"^^xsd:double ;
        gpml:centerY             "315.0"^^xsd:double ;
        gpml:color               "0" ;
        gpml:fillColor           "ffffff" ;
        gpml:fontDecoration      "Normal" ;
        gpml:fontName            "Arial" ;
        gpml:fontSize            "12.0"^^xsd:double ;
        gpml:fontStrikethru      "Normal" ;
        gpml:fontStyle           "Normal" ;
        gpml:fontWeight          "Normal" ;
        gpml:graphId             "e19dd" ;
        gpml:hasPublicationXref  <https://identifiers.org/pubmed/33662138> , <https://identifiers.org/pubmed/27638206> ;
        gpml:height              "25.0"^^xsd:double ;
        gpml:lineStyle           "Solid" ;
        gpml:lineThickness       "1.0"^^xsd:double ;
        gpml:shapeType           "Rectangle" ;
        gpml:textlabel           "CisXMT2" ;
        gpml:type                "GeneProduct" ;
        gpml:valign              "Middle" ;
        gpml:width               "90.0"^^xsd:double ;
        gpml:xrefDataSource      "" ;
        gpml:xrefId              "" ;
        gpml:zorder              "32768"^^xsd:long .

<https://identifiers.org/pubmed/33662138>
        rdf:type          gpml:PublicationXref ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5589_r141384/DataNode/fb21b> , <http://rdf.wikipathways.org/Pathway/WP5589_r141384/DataNode/efb38> , <http://rdf.wikipathways.org/Pathway/WP5589_r141384/DataNode/cad83> , <http://rdf.wikipathways.org/Pathway/WP5589_r141384/DataNode/e19dd> , <http://rdf.wikipathways.org/Pathway/WP5589_r141384/DataNode/faccf> , <http://rdf.wikipathways.org/Pathway/WP5589_r141384/DataNode/ce038> , <http://rdf.wikipathways.org/Pathway/WP5589_r141384/DataNode/c48b0> ;
        gpml:database     "Pubmed" ;
        gpml:id           "33662138" .

<http://rdf.wikipathways.org/Pathway/WP5589_r141384/Interaction/id4b86a8bd/Anchor/c4015>
        rdf:type          gpml:Anchor ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5589_r141384> , <http://rdf.wikipathways.org/Pathway/WP5589_r141384/Interaction/id4b86a8bd> ;
        gpml:graphId      "c4015" ;
        gpml:position     "0.4"^^xsd:double ;
        gpml:shape        "None" .

<http://rdf.wikipathways.org/Pathway/WP5589_r141384/Interaction/id6df473fe>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP5589_r141384> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "id6df473fe" ;
        gpml:hasAnchor      <http://rdf.wikipathways.org/Pathway/WP5589_r141384/Interaction/id6df473fe/Anchor/c99e3> ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP5589_r141384/Interaction/id6df473fe/Point/9fed4b1e4289be5117c53410e09994ae> , <http://rdf.wikipathways.org/Pathway/WP5589_r141384/Interaction/id6df473fe/Point/783778a72037d897202b7a894636df1> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5589_r141384/Interaction/id6df473fe/Anchor/c99e3>
        rdf:type          gpml:Anchor ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5589_r141384> , <http://rdf.wikipathways.org/Pathway/WP5589_r141384/Interaction/id6df473fe> ;
        gpml:graphId      "c99e3" ;
        gpml:position     "0.4"^^xsd:double ;
        gpml:shape        "None" .

<http://rdf.wikipathways.org/Pathway/WP5589_r141384/Interaction/id4e7c26c2/Point/e59e89ca1c259172ecbf48949b0f6591>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5589_r141384> , <http://rdf.wikipathways.org/Pathway/WP5589_r141384/Interaction/id4e7c26c2> ;
        gpml:graphRef     "c48b0" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "215.0"^^xsd:double ;
        gpml:y            "65.25"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5589_r141384/Interaction/id4b86a8bd>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP5589_r141384> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "id4b86a8bd" ;
        gpml:hasAnchor      <http://rdf.wikipathways.org/Pathway/WP5589_r141384/Interaction/id4b86a8bd/Anchor/c4015> ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP5589_r141384/Interaction/id4b86a8bd/Point/f99e799cfdf214acd8e9e3d2ee03478e> , <http://rdf.wikipathways.org/Pathway/WP5589_r141384/Interaction/id4b86a8bd/Point/97b6d8f4be3056556197fb5410447e25> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5589_r141384/Interaction/id31a3cf55>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP5589_r141384> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "id31a3cf55" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP5589_r141384/Interaction/id31a3cf55/Point/9f13d9849e5632d18ae8ae877f04519f> , <http://rdf.wikipathways.org/Pathway/WP5589_r141384/Interaction/id31a3cf55/Point/fd4c456982cb05d64d60d00e31e822e0> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5589_r141384/DataNode/ce038>
        rdf:type                 gpml:DataNode ;
        dcterms:isPartOf         <http://rdf.wikipathways.org/Pathway/WP5589_r141384> ;
        gpml:align               "Center" ;
        gpml:biopaxRef           "f35" , "a42" ;
        gpml:centerX             "350.5"^^xsd:double ;
        gpml:centerY             "184.0"^^xsd:double ;
        gpml:color               "ff" ;
        gpml:fillColor           "ffffff" ;
        gpml:fontDecoration      "Normal" ;
        gpml:fontName            "Arial" ;
        gpml:fontSize            "12.0"^^xsd:double ;
        gpml:fontStrikethru      "Normal" ;
        gpml:fontStyle           "Normal" ;
        gpml:fontWeight          "Normal" ;
        gpml:graphId             "ce038" ;
        gpml:hasPublicationXref  <https://identifiers.org/pubmed/27638206> , <https://identifiers.org/pubmed/33662138> ;
        gpml:height              "25.0"^^xsd:double ;
        gpml:lineStyle           "Solid" ;
        gpml:lineThickness       "1.0"^^xsd:double ;
        gpml:shapeType           "Rectangle" ;
        gpml:textlabel           "3-methylxanthine" ;
        gpml:type                "Metabolite" ;
        gpml:valign              "Middle" ;
        gpml:width               "145.0"^^xsd:double ;
        gpml:xrefDataSource      "ChEBI" ;
        gpml:xrefId              "CHEBI:62208" ;
        gpml:zorder              "32768"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5589_r141384/Interaction/id34c09683>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP5589_r141384> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "id34c09683" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP5589_r141384/Interaction/id34c09683/Point/c1cc9446085c4cae045f26cf77525212> , <http://rdf.wikipathways.org/Pathway/WP5589_r141384/Interaction/id34c09683/Point/39c35511e9bb19be51e16f0d3d7e7b3d> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5589_r141384/Interaction/idcfc1f0e0/Point/1ed081588ff9b56e2381d90acbff3236>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5589_r141384> , <http://rdf.wikipathways.org/Pathway/WP5589_r141384/Interaction/idcfc1f0e0> ;
        gpml:graphRef     "fb21b" ;
        gpml:relX         "-0.5"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "192.5"^^xsd:double ;
        gpml:y            "171.5"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5589_r141384/Interaction/id4e7c26c2/Anchor/aad58>
        rdf:type          gpml:Anchor ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5589_r141384> , <http://rdf.wikipathways.org/Pathway/WP5589_r141384/Interaction/id4e7c26c2> ;
        gpml:graphId      "aad58" ;
        gpml:position     "0.4"^^xsd:double ;
        gpml:shape        "None" .

<https://identifiers.org/pubmed/23471406>
        rdf:type          gpml:PublicationXref ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5589_r141384/DataNode/efb38> ;
        gpml:database     "Pubmed" ;
        gpml:id           "23471406" .

<https://identifiers.org/pubmed/27638206>
        rdf:type          gpml:PublicationXref ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5589_r141384/DataNode/faccf> , <http://rdf.wikipathways.org/Pathway/WP5589_r141384/DataNode/ce038> , <http://rdf.wikipathways.org/Pathway/WP5589_r141384/DataNode/e19dd> , <http://rdf.wikipathways.org/Pathway/WP5589_r141384/DataNode/c48b0> , <http://rdf.wikipathways.org/Pathway/WP5589_r141384/DataNode/efb38> , <http://rdf.wikipathways.org/Pathway/WP5589_r141384/DataNode/fb21b> , <http://rdf.wikipathways.org/Pathway/WP5589_r141384/DataNode/cad83> ;
        gpml:database     "Pubmed" ;
        gpml:id           "27638206" .

<http://rdf.wikipathways.org/Pathway/WP5589_r141384/Interaction/id34c09683/Point/39c35511e9bb19be51e16f0d3d7e7b3d>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5589_r141384> , <http://rdf.wikipathways.org/Pathway/WP5589_r141384/Interaction/id34c09683> ;
        gpml:graphRef     "aad58" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "269.2"^^xsd:double ;
        gpml:y            "107.75"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5589_r141384/Interaction/id3ffb1853/Point/e6a5ccc3a8979e5a8fa471edccfa04eb>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5589_r141384> , <http://rdf.wikipathways.org/Pathway/WP5589_r141384/Interaction/id3ffb1853> ;
        gpml:graphRef     "ce038" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "350.5"^^xsd:double ;
        gpml:y            "196.5"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5589_r141384/Interaction/idf84076d6/Anchor/ffe6b>
        rdf:type          gpml:Anchor ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5589_r141384> , <http://rdf.wikipathways.org/Pathway/WP5589_r141384/Interaction/idf84076d6> ;
        gpml:graphId      "ffe6b" ;
        gpml:position     "0.4"^^xsd:double ;
        gpml:shape        "None" .

<http://rdf.wikipathways.org/Pathway/WP5589_r141384/Interaction/idf84076d6/Point/e99455dd85e40a8cf5417d08ee3c7620>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5589_r141384> , <http://rdf.wikipathways.org/Pathway/WP5589_r141384/Interaction/idf84076d6> ;
        gpml:graphRef     "cad83" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "79.0"^^xsd:double ;
        gpml:y            "171.5"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5589_r141384/Interaction/id4e7c26c2/Point/8f366908d858f6ea146c643ebfcf4f3>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5589_r141384> , <http://rdf.wikipathways.org/Pathway/WP5589_r141384/Interaction/id4e7c26c2> ;
        gpml:graphRef     "ce038" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "350.5"^^xsd:double ;
        gpml:y            "171.5"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5589_r141384/Interaction/id31a3cf55/Point/fd4c456982cb05d64d60d00e31e822e0>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5589_r141384> , <http://rdf.wikipathways.org/Pathway/WP5589_r141384/Interaction/id31a3cf55> ;
        gpml:graphRef     "be9a5" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "305.3"^^xsd:double ;
        gpml:y            "227.2"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5589_r141384/DataNode/cad83>
        rdf:type                 gpml:DataNode ;
        dcterms:isPartOf         <http://rdf.wikipathways.org/Pathway/WP5589_r141384> ;
        gpml:align               "Center" ;
        gpml:biopaxRef           "a42" , "f35" ;
        gpml:centerX             "79.0"^^xsd:double ;
        gpml:centerY             "184.0"^^xsd:double ;
        gpml:color               "ff" ;
        gpml:fillColor           "ffffff" ;
        gpml:fontDecoration      "Normal" ;
        gpml:fontName            "Arial" ;
        gpml:fontSize            "12.0"^^xsd:double ;
        gpml:fontStrikethru      "Normal" ;
        gpml:fontStyle           "Normal" ;
        gpml:fontWeight          "Normal" ;
        gpml:graphId             "cad83" ;
        gpml:hasPublicationXref  <https://identifiers.org/pubmed/33662138> , <https://identifiers.org/pubmed/27638206> ;
        gpml:height              "25.0"^^xsd:double ;
        gpml:lineStyle           "Solid" ;
        gpml:lineThickness       "1.0"^^xsd:double ;
        gpml:shapeType           "Rectangle" ;
        gpml:textlabel           "1-methylxanthine" ;
        gpml:type                "Metabolite" ;
        gpml:valign              "Middle" ;
        gpml:width               "140.0"^^xsd:double ;
        gpml:xrefDataSource      "ChEBI" ;
        gpml:xrefId              "CHEBI:68443" ;
        gpml:zorder              "32768"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5589_r141384/Interaction/id49054ad1/Point/cc13397e8040cba488d9ef2e97c0373d>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5589_r141384> , <http://rdf.wikipathways.org/Pathway/WP5589_r141384/Interaction/id49054ad1> ;
        gpml:graphRef     "e19dd" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "313.0"^^xsd:double ;
        gpml:y            "315.0"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5589_r141384/Interaction/id4e7c26c2>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP5589_r141384> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "id4e7c26c2" ;
        gpml:hasAnchor      <http://rdf.wikipathways.org/Pathway/WP5589_r141384/Interaction/id4e7c26c2/Anchor/aad58> ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP5589_r141384/Interaction/id4e7c26c2/Point/e59e89ca1c259172ecbf48949b0f6591> , <http://rdf.wikipathways.org/Pathway/WP5589_r141384/Interaction/id4e7c26c2/Point/8f366908d858f6ea146c643ebfcf4f3> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5589_r141384/Interaction/id6df473fe/Point/783778a72037d897202b7a894636df1>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5589_r141384> , <http://rdf.wikipathways.org/Pathway/WP5589_r141384/Interaction/id6df473fe> ;
        gpml:graphRef     "faccf" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "215.0"^^xsd:double ;
        gpml:y            "298.25"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5589_r141384/Interaction/id3ffb1853/Point/ccdc533a8ae60da9c43e37c8e888e47b>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5589_r141384> , <http://rdf.wikipathways.org/Pathway/WP5589_r141384/Interaction/id3ffb1853> ;
        gpml:graphRef     "faccf" ;
        gpml:relX         "0.5"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "237.5"^^xsd:double ;
        gpml:y            "273.25"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5589_r141384/Interaction/idf84076d6>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP5589_r141384> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "idf84076d6" ;
        gpml:hasAnchor      <http://rdf.wikipathways.org/Pathway/WP5589_r141384/Interaction/idf84076d6/Anchor/ffe6b> ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP5589_r141384/Interaction/idf84076d6/Point/e99455dd85e40a8cf5417d08ee3c7620> , <http://rdf.wikipathways.org/Pathway/WP5589_r141384/Interaction/idf84076d6/Point/795377ad664f8df538a808b3b597a722> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5589_r141384/DataNode/efb38>
        rdf:type                 gpml:DataNode ;
        dcterms:isPartOf         <http://rdf.wikipathways.org/Pathway/WP5589_r141384> ;
        gpml:align               "Center" ;
        gpml:biopaxRef           "a42" , "a9d" , "f35" ;
        gpml:centerX             "215.0"^^xsd:double ;
        gpml:centerY             "359.0"^^xsd:double ;
        gpml:color               "ff" ;
        gpml:fillColor           "ffffff" ;
        gpml:fontDecoration      "Normal" ;
        gpml:fontName            "Arial" ;
        gpml:fontSize            "12.0"^^xsd:double ;
        gpml:fontStrikethru      "Normal" ;
        gpml:fontStyle           "Normal" ;
        gpml:fontWeight          "Normal" ;
        gpml:graphId             "efb38" ;
        gpml:hasPublicationXref  <https://identifiers.org/pubmed/33662138> , <https://identifiers.org/pubmed/23471406> , <https://identifiers.org/pubmed/27638206> ;
        gpml:height              "25.0"^^xsd:double ;
        gpml:lineStyle           "Solid" ;
        gpml:lineThickness       "1.0"^^xsd:double ;
        gpml:shapeType           "Rectangle" ;
        gpml:textlabel           "Caffeine" ;
        gpml:type                "Metabolite" ;
        gpml:valign              "Middle" ;
        gpml:width               "90.0"^^xsd:double ;
        gpml:xrefDataSource      "ChEBI" ;
        gpml:xrefId              "CHEBI:27732" ;
        gpml:zorder              "32768"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5589_r141384/Interaction/id31a3cf55/Point/9f13d9849e5632d18ae8ae877f04519f>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5589_r141384> , <http://rdf.wikipathways.org/Pathway/WP5589_r141384/Interaction/id31a3cf55> ;
        gpml:graphRef     "fb21b" ;
        gpml:relX         "0.5"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "237.5"^^xsd:double ;
        gpml:y            "196.5"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5589_r141384/Interaction/id1affc3c0>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP5589_r141384> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "id1affc3c0" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP5589_r141384/Interaction/id1affc3c0/Point/60ea1e359d6c8de45c571e10ec3d0b8> , <http://rdf.wikipathways.org/Pathway/WP5589_r141384/Interaction/id1affc3c0/Point/49c20b845a96517f6a09ddd051cd2bea> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5589_r141384/Interaction/id49054ad1/Point/da6960ae29fc27bd06a0cf118544687c>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5589_r141384> , <http://rdf.wikipathways.org/Pathway/WP5589_r141384/Interaction/id49054ad1> ;
        gpml:graphRef     "c99e3" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "215.0"^^xsd:double ;
        gpml:y            "317.55"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5589_r141384/Interaction/idf84076d6/Point/795377ad664f8df538a808b3b597a722>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5589_r141384> , <http://rdf.wikipathways.org/Pathway/WP5589_r141384/Interaction/idf84076d6> ;
        gpml:graphRef     "c48b0" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "215.0"^^xsd:double ;
        gpml:y            "65.25"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5589_r141384/InfoBox/a59417f98d781f097732120efdfd396a>
        rdf:type          gpml:InfoBox ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5589_r141384> ;
        gpml:centerX      "0.0"^^xsd:double ;
        gpml:centerY      "0.0"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5589_r141384/Interaction/id1affc3c0/Point/60ea1e359d6c8de45c571e10ec3d0b8>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5589_r141384> , <http://rdf.wikipathways.org/Pathway/WP5589_r141384/Interaction/id1affc3c0> ;
        gpml:graphRef     "c4015" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "124.4"^^xsd:double ;
        gpml:y            "227.2"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5589_r141384/Interaction/id4b86a8bd/Point/97b6d8f4be3056556197fb5410447e25>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5589_r141384> , <http://rdf.wikipathways.org/Pathway/WP5589_r141384/Interaction/id4b86a8bd> ;
        gpml:graphRef     "cad83" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "79.0"^^xsd:double ;
        gpml:y            "196.5"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5589_r141384/Interaction/idcfc1f0e0/Point/eba1de28f5174788c51a8ec899562bbf>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5589_r141384> , <http://rdf.wikipathways.org/Pathway/WP5589_r141384/Interaction/idcfc1f0e0> ;
        gpml:graphRef     "ffe6b" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "160.6"^^xsd:double ;
        gpml:y            "107.75"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5589_r141384>
        rdfs:seeAlso         <https://www.wikipathways.org/instance/WP5589_r141384> ;
        gpml:author          "[Hayashi, MaintBot, Egonw, Eweitz]" ;
        gpml:biopaxRef       "f35" , "a42" ;
        gpml:boardHeight     "401.5"^^xsd:double ;
        gpml:boardWidth      "453.0"^^xsd:double ;
        gpml:data-Source     "WikiPathways" ;
        gpml:hasDataNode     <http://rdf.wikipathways.org/Pathway/WP5589_r141384/DataNode/faccf> , <http://rdf.wikipathways.org/Pathway/WP5589_r141384/DataNode/ce038> , <http://rdf.wikipathways.org/Pathway/WP5589_r141384/DataNode/c48b0> , <http://rdf.wikipathways.org/Pathway/WP5589_r141384/DataNode/cad83> , <http://rdf.wikipathways.org/Pathway/WP5589_r141384/DataNode/efb38> , <http://rdf.wikipathways.org/Pathway/WP5589_r141384/DataNode/e19dd> , <http://rdf.wikipathways.org/Pathway/WP5589_r141384/DataNode/fb21b> ;
        gpml:hasInfoBox      <http://rdf.wikipathways.org/Pathway/WP5589_r141384/InfoBox/a59417f98d781f097732120efdfd396a> ;
        gpml:hasInteraction  <http://rdf.wikipathways.org/Pathway/WP5589_r141384/Interaction/id34c09683> , <http://rdf.wikipathways.org/Pathway/WP5589_r141384/Interaction/id1affc3c0> , <http://rdf.wikipathways.org/Pathway/WP5589_r141384/Interaction/id4b86a8bd> , <http://rdf.wikipathways.org/Pathway/WP5589_r141384/Interaction/idf84076d6> , <http://rdf.wikipathways.org/Pathway/WP5589_r141384/Interaction/id31a3cf55> , <http://rdf.wikipathways.org/Pathway/WP5589_r141384/Interaction/idcfc1f0e0> , <http://rdf.wikipathways.org/Pathway/WP5589_r141384/Interaction/id6df473fe> , <http://rdf.wikipathways.org/Pathway/WP5589_r141384/Interaction/id3ffb1853> , <http://rdf.wikipathways.org/Pathway/WP5589_r141384/Interaction/id4e7c26c2> , <http://rdf.wikipathways.org/Pathway/WP5589_r141384/Interaction/id49054ad1> ;
        gpml:last-Modified   "20251111141445" ;
        gpml:name            "Caffeine synthesis" ;
        gpml:organism        "Citrus sinensis" ;
        gpml:version         "WP5589_r141384" .

<http://rdf.wikipathways.org/Pathway/WP5589_r141384/Interaction/id3ffb1853>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP5589_r141384> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "id3ffb1853" ;
        gpml:hasAnchor      <http://rdf.wikipathways.org/Pathway/WP5589_r141384/Interaction/id3ffb1853/Anchor/be9a5> ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP5589_r141384/Interaction/id3ffb1853/Point/ccdc533a8ae60da9c43e37c8e888e47b> , <http://rdf.wikipathways.org/Pathway/WP5589_r141384/Interaction/id3ffb1853/Point/e6a5ccc3a8979e5a8fa471edccfa04eb> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5589_r141384/Interaction/id49054ad1>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP5589_r141384> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "id49054ad1" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP5589_r141384/Interaction/id49054ad1/Point/da6960ae29fc27bd06a0cf118544687c> , <http://rdf.wikipathways.org/Pathway/WP5589_r141384/Interaction/id49054ad1/Point/cc13397e8040cba488d9ef2e97c0373d> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5589_r141384/Interaction/id4b86a8bd/Point/f99e799cfdf214acd8e9e3d2ee03478e>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5589_r141384> , <http://rdf.wikipathways.org/Pathway/WP5589_r141384/Interaction/id4b86a8bd> ;
        gpml:graphRef     "faccf" ;
        gpml:relX         "-0.5"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "192.5"^^xsd:double ;
        gpml:y            "273.25"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5589_r141384/Interaction/id6df473fe/Point/9fed4b1e4289be5117c53410e09994ae>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5589_r141384> , <http://rdf.wikipathways.org/Pathway/WP5589_r141384/Interaction/id6df473fe> ;
        gpml:graphRef     "efb38" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "215.0"^^xsd:double ;
        gpml:y            "346.5"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5589_r141384/DataNode/c48b0>
        rdf:type                 gpml:DataNode ;
        dcterms:isPartOf         <http://rdf.wikipathways.org/Pathway/WP5589_r141384> ;
        gpml:align               "Center" ;
        gpml:biopaxRef           "a42" , "f35" ;
        gpml:centerX             "215.0"^^xsd:double ;
        gpml:centerY             "52.75"^^xsd:double ;
        gpml:color               "ff" ;
        gpml:fillColor           "ffffff" ;
        gpml:fontDecoration      "Normal" ;
        gpml:fontName            "Arial" ;
        gpml:fontSize            "12.0"^^xsd:double ;
        gpml:fontStrikethru      "Normal" ;
        gpml:fontStyle           "Normal" ;
        gpml:fontWeight          "Normal" ;
        gpml:graphId             "c48b0" ;
        gpml:hasPublicationXref  <https://identifiers.org/pubmed/27638206> , <https://identifiers.org/pubmed/33662138> ;
        gpml:height              "25.0"^^xsd:double ;
        gpml:lineStyle           "Solid" ;
        gpml:lineThickness       "1.0"^^xsd:double ;
        gpml:shapeType           "Rectangle" ;
        gpml:textlabel           "Xanthine" ;
        gpml:type                "Metabolite" ;
        gpml:valign              "Middle" ;
        gpml:width               "90.0"^^xsd:double ;
        gpml:xrefDataSource      "ChEBI" ;
        gpml:xrefId              "CHEBI:15318" ;
        gpml:zorder              "32768"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5589_r141384/Interaction/id34c09683/Point/c1cc9446085c4cae045f26cf77525212>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5589_r141384> , <http://rdf.wikipathways.org/Pathway/WP5589_r141384/Interaction/id34c09683> ;
        gpml:graphRef     "fb21b" ;
        gpml:relX         "0.5"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "237.5"^^xsd:double ;
        gpml:y            "171.5"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5589_r141384/DataNode/fb21b>
        rdf:type                 gpml:DataNode ;
        dcterms:isPartOf         <http://rdf.wikipathways.org/Pathway/WP5589_r141384> ;
        gpml:align               "Center" ;
        gpml:biopaxRef           "a42" , "f35" ;
        gpml:centerX             "215.0"^^xsd:double ;
        gpml:centerY             "184.0"^^xsd:double ;
        gpml:color               "0" ;
        gpml:fillColor           "ffffff" ;
        gpml:fontDecoration      "Normal" ;
        gpml:fontName            "Arial" ;
        gpml:fontSize            "12.0"^^xsd:double ;
        gpml:fontStrikethru      "Normal" ;
        gpml:fontStyle           "Normal" ;
        gpml:fontWeight          "Normal" ;
        gpml:graphId             "fb21b" ;
        gpml:hasPublicationXref  <https://identifiers.org/pubmed/33662138> , <https://identifiers.org/pubmed/27638206> ;
        gpml:height              "25.0"^^xsd:double ;
        gpml:lineStyle           "Solid" ;
        gpml:lineThickness       "1.0"^^xsd:double ;
        gpml:shapeType           "Rectangle" ;
        gpml:textlabel           "CisXMT1" ;
        gpml:type                "GeneProduct" ;
        gpml:valign              "Middle" ;
        gpml:width               "90.0"^^xsd:double ;
        gpml:xrefDataSource      "" ;
        gpml:xrefId              "" ;
        gpml:zorder              "32768"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5589_r141384/DataNode/faccf>
        rdf:type                 gpml:DataNode ;
        dcterms:isPartOf         <http://rdf.wikipathways.org/Pathway/WP5589_r141384> ;
        gpml:align               "Center" ;
        gpml:biopaxRef           "f35" , "a42" ;
        gpml:centerX             "215.0"^^xsd:double ;
        gpml:centerY             "285.75"^^xsd:double ;
        gpml:color               "ff" ;
        gpml:fillColor           "ffffff" ;
        gpml:fontDecoration      "Normal" ;
        gpml:fontName            "Arial" ;
        gpml:fontSize            "12.0"^^xsd:double ;
        gpml:fontStrikethru      "Normal" ;
        gpml:fontStyle           "Normal" ;
        gpml:fontWeight          "Normal" ;
        gpml:graphId             "faccf" ;
        gpml:hasPublicationXref  <https://identifiers.org/pubmed/33662138> , <https://identifiers.org/pubmed/27638206> ;
        gpml:height              "25.0"^^xsd:double ;
        gpml:lineStyle           "Solid" ;
        gpml:lineThickness       "1.0"^^xsd:double ;
        gpml:shapeType           "Rectangle" ;
        gpml:textlabel           "Theophylline" ;
        gpml:type                "Metabolite" ;
        gpml:valign              "Middle" ;
        gpml:width               "90.0"^^xsd:double ;
        gpml:xrefDataSource      "ChEBI" ;
        gpml:xrefId              "CHEBI:28177" ;
        gpml:zorder              "32768"^^xsd:long .
