@prefix biopax:  <http://www.biopax.org/release/biopax-level3.owl#> .
@prefix cito:    <http://purl.org/spar/cito/> .
@prefix dc:      <http://purl.org/dc/elements/1.1/> .
@prefix dcterms: <http://purl.org/dc/terms/> .
@prefix foaf:    <http://xmlns.com/foaf/0.1/> .
@prefix freq:    <http://purl.org/cld/freq/> .
@prefix gpml:    <http://vocabularies.wikipathways.org/gpml#> .
@prefix obo:     <http://purl.obolibrary.org/obo/> .
@prefix owl:     <http://www.w3.org/2002/07/owl#> .
@prefix pav:     <http://purl.org/pav/> .
@prefix prov:    <http://www.w3.org/ns/prov#> .
@prefix rdf:     <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix rdfs:    <http://www.w3.org/2000/01/rdf-schema#> .
@prefix skos:    <http://www.w3.org/2004/02/skos/core#> .
@prefix void:    <http://rdfs.org/ns/void#> .
@prefix wp:      <http://vocabularies.wikipathways.org/wp#> .
@prefix wprdf:   <http://rdf.wikipathways.org/> .
@prefix xsd:     <http://www.w3.org/2001/XMLSchema#> .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/DataNode/d367c>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP3630_r138896> ;
        gpml:align           "Center" ;
        gpml:centerX         "382.7352941176475"^^xsd:double ;
        gpml:centerY         "486.7647058823536"^^xsd:double ;
        gpml:color           "ff" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "10.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "d367c" ;
        gpml:hasComment      <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Comment/25645da7cc0def1f341d781bf329a280> ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "PARP inhibitors" ;
        gpml:type            "Metabolite" ;
        gpml:valign          "Middle" ;
        gpml:width           "80.0"^^xsd:double ;
        gpml:xrefDataSource  "ChEBI" ;
        gpml:xrefId          "CHEBI:83766" ;
        gpml:zorder          "32790"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/idf1fbe4ee/Point/a60d92c93621e173b488516560d5e8eb>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP3630_r138896> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/idf1fbe4ee> ;
        gpml:graphRef     "b1532" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "654.4561718844093"^^xsd:double ;
        gpml:y            "114.10032483783007"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/id1947cd81/Point/920abad66537b828af6f0599314551bf>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP3630_r138896> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/id1947cd81> ;
        gpml:graphRef     "d9a24" ;
        gpml:relX         "1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "168.0"^^xsd:double ;
        gpml:y            "371.0"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/Label/a6c43>
        rdf:type             gpml:Label ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP3630_r138896> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Group/ac809> ;
        gpml:align           "Center" ;
        gpml:centerX         "764.4114353432403"^^xsd:double ;
        gpml:centerY         "266.4265506915547"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Bold" ;
        gpml:graphId         "a6c43" ;
        gpml:groupRef        "f00ca" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:href            "" ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "None" ;
        gpml:textlabel       "Skeletal muscle" ;
        gpml:valign          "Middle" ;
        gpml:width           "108.0"^^xsd:double ;
        gpml:zorder          "32796"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/id1549585d/Point/9f13d9849e5632d18ae8ae877f04519f>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP3630_r138896> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/id1549585d> ;
        gpml:graphRef     "a1e1d" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "382.36974789915905"^^xsd:double ;
        gpml:y            "360.9339350970843"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/Label/f83b2>
        rdf:type             gpml:Label ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP3630_r138896> ;
        gpml:align           "Center" ;
        gpml:centerX         "146.7787255182636"^^xsd:double ;
        gpml:centerY         "297.05882352941245"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Bold" ;
        gpml:graphId         "f83b2" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:href            "" ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "None" ;
        gpml:textlabel       "Aging" ;
        gpml:valign          "Middle" ;
        gpml:width           "63.655462184874374"^^xsd:double ;
        gpml:zorder          "28675"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/iddb37003a>
        rdf:type                 gpml:Interaction ;
        dcterms:isPartOf         <http://rdf.wikipathways.org/Pathway/WP3630_r138896> ;
        gpml:biopaxRef           "c17" , "a72" ;
        gpml:color               "ff9900" ;
        gpml:connectorType       "Elbow" ;
        gpml:graphId             "iddb37003a" ;
        gpml:hasPoint            <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/iddb37003a/Point/53b07c85dfa2d58118444c5b51c8c0d3> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/iddb37003a/Point/6e0a8d43aa2518213fff16c96db46c6a> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/iddb37003a/Point/2e438e43589bf8701f115178890ad8f1> ;
        gpml:hasPublicationXref  <https://identifiers.org/pubmed/19470756> , <https://identifiers.org/pubmed/16628003> ;
        gpml:lineStyle           "Solid" ;
        gpml:lineThickness       "1.0"^^xsd:double ;
        gpml:zorder              "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/idf1fbe4ee>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP3630_r138896> ;
        gpml:color          "0" ;
        gpml:connectorType  "Elbow" ;
        gpml:graphId        "idf1fbe4ee" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/idf1fbe4ee/Point/5679a96f2bb692a149b4fd94fb787360> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/idf1fbe4ee/Point/a60d92c93621e173b488516560d5e8eb> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/idf1fbe4ee/Point/57357f603b553323f3e2f7d024b6c018> ;
        gpml:lineStyle      "Broken" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/df457/Point/7fa56b6715d26a66efc5044d86a3d659>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP3630_r138896> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/df457> ;
        gpml:graphRef     "bdc90" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "616.4561718844093"^^xsd:double ;
        gpml:y            "331.07332967102604"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/b1f69/Point/4dee1c60801324531078738ca2b1f335>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP3630_r138896> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/b1f69> ;
        gpml:graphRef     "b74eb" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "352.1890756302514"^^xsd:double ;
        gpml:y            "149.4789915966383"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/Label/ad499>
        rdf:type             gpml:Label ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Group/ac809> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896> ;
        gpml:align           "Center" ;
        gpml:centerX         "743.361015175173"^^xsd:double ;
        gpml:centerY         "138.2332733806307"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Bold" ;
        gpml:graphId         "ad499" ;
        gpml:groupRef        "f00ca" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:href            "" ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "None" ;
        gpml:textlabel       "Pancreas" ;
        gpml:valign          "Middle" ;
        gpml:width           "108.0"^^xsd:double ;
        gpml:zorder          "32784"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/e4cc8>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP3630_r138896> ;
        gpml:color          "0" ;
        gpml:connectorType  "Elbow" ;
        gpml:graphId        "e4cc8" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/e4cc8/Point/8b94c069feb24a28d87ac9e05d356f15> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/e4cc8/Point/8790f516c7a6e62ac582bf70899eec8a> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/e4cc8/Point/30fd8554ccde79ec0c17044434a32e01> ;
        gpml:lineStyle      "Broken" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "32793"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/df457/Point/17ece6d7131461bf9a8c714950f48eed>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP3630_r138896> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/df457> ;
        gpml:graphRef     "bdb6e" ;
        gpml:relX         "1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "538.0832589548863"^^xsd:double ;
        gpml:y            "349.1992893349725"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/e2982/Point/1797fdd1848738bed129019640e6ae74>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP3630_r138896> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/e2982> ;
        gpml:graphRef     "d367c" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "382.7352941176475"^^xsd:double ;
        gpml:y            "476.7647058823536"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/DataNode/d3b0f>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Group/aa34f> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896> ;
        gpml:align           "Center" ;
        gpml:centerX         "654.6579359417424"^^xsd:double ;
        gpml:centerY         "185.83830020950992"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "10.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "d3b0f" ;
        gpml:groupRef        "e3706" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "FOXO3" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "60.0"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000118689" ;
        gpml:zorder          "32775"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/id1947cd81>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP3630_r138896> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "id1947cd81" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/id1947cd81/Point/aabf1bd82f6fbcfc34450c84a8a953ad> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/id1947cd81/Point/920abad66537b828af6f0599314551bf> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/DataNode/d9366>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP3630_r138896> ;
        gpml:align           "Center" ;
        gpml:centerX         "508.1316751149351"^^xsd:double ;
        gpml:centerY         "220.20381940351228"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "10.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "d9366" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "SIRT1" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "60.0"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000096717" ;
        gpml:zorder          "32770"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/DataNode/b74eb>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP3630_r138896> ;
        gpml:align           "Center" ;
        gpml:centerX         "382.1890756302514"^^xsd:double ;
        gpml:centerY         "149.4789915966383"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "10.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "b74eb" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "NAMPT" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "60.0"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000105835" ;
        gpml:zorder          "32768"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/Label/ca320>
        rdf:type             gpml:Label ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP3630_r138896> ;
        gpml:align           "Center" ;
        gpml:centerX         "688.1422845691379"^^xsd:double ;
        gpml:centerY         "474.2079453023691"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "ca320" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:href            "" ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "None" ;
        gpml:textlabel       "Depletion" ;
        gpml:valign          "Middle" ;
        gpml:width           "85.15030060120192"^^xsd:double ;
        gpml:zorder          "32806"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/ae3ab/Point/fce0343460a8f27d9aa7232526b25d2e>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP3630_r138896> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/ae3ab> ;
        gpml:graphRef     "bdb6e" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "478.08325895488633"^^xsd:double ;
        gpml:y            "349.1992893349725"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/idb0edb154/Point/1ed081588ff9b56e2381d90acbff3236>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP3630_r138896> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/idb0edb154> ;
        gpml:graphRef     "d49ba" ;
        gpml:relX         "1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "139.93277310924367"^^xsd:double ;
        gpml:y            "149.53781512605022"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/id51a6de8f>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP3630_r138896> ;
        gpml:color          "0" ;
        gpml:connectorType  "Elbow" ;
        gpml:graphId        "id51a6de8f" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/id51a6de8f/Point/f99e799cfdf214acd8e9e3d2ee03478e> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/id51a6de8f/Point/97b6d8f4be3056556197fb5410447e25> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/DataNode/a1e1d>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP3630_r138896> ;
        gpml:align           "Center" ;
        gpml:centerX         "382.36974789915905"^^xsd:double ;
        gpml:centerY         "370.9339350970843"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "10.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "a1e1d" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "PARP1" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "60.0"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000143799" ;
        gpml:zorder          "32768"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/id3c940720/Point/da6960ae29fc27bd06a0cf118544687c>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP3630_r138896> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/id3c940720> ;
        gpml:graphRef     "d9366" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "478.1316751149351"^^xsd:double ;
        gpml:y            "220.20381940351228"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/idd9b01f7/Point/e93c6510633a9fecde87080ef20ec4c2>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP3630_r138896> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/idd9b01f7> ;
        gpml:graphRef     "abfa0" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "624.4561718844092"^^xsd:double ;
        gpml:y            "377.29576977048043"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/Label/f5a65>
        rdf:type             gpml:Label ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP3630_r138896> ;
        gpml:align           "Center" ;
        gpml:centerX         "232.2773109243704"^^xsd:double ;
        gpml:centerY         "149.53781512605036"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Bold" ;
        gpml:graphId         "f5a65" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:href            "" ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "None" ;
        gpml:textlabel       "Inflammation" ;
        gpml:valign          "Middle" ;
        gpml:width           "96.0"^^xsd:double ;
        gpml:zorder          "28673"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/b1f69/Point/e152776e0b695612e17e4d3970394af8>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP3630_r138896> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/b1f69> ;
        gpml:graphRef     "f5a65" ;
        gpml:relX         "1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "280.2773109243704"^^xsd:double ;
        gpml:y            "149.53781512605036"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/DataNode/c0597>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP3630_r138896> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Group/aa34f> ;
        gpml:align           "Center" ;
        gpml:centerX         "654.6579359417424"^^xsd:double ;
        gpml:centerY         "210.22084681532618"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "10.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "c0597" ;
        gpml:groupRef        "e3706" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "TFAM" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "60.0"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000108064" ;
        gpml:zorder          "32776"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/id1947cd81/Point/aabf1bd82f6fbcfc34450c84a8a953ad>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP3630_r138896> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/id1947cd81> ;
        gpml:graphRef     "d538c" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "215.57744059547673"^^xsd:double ;
        gpml:y            "370.7910779542274"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/ide7a6c22/Point/2ff6cb254f4d58bfa646637b27304bf2>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP3630_r138896> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/ide7a6c22> ;
        gpml:graphRef     "d9366" ;
        gpml:relX         "0.5"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "523.1316751149351"^^xsd:double ;
        gpml:y            "210.20381940351228"^^xsd:double .

<https://identifiers.org/pubmed/19470756>
        rdf:type          gpml:PublicationXref ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/iddb37003a> ;
        gpml:database     "Pubmed" ;
        gpml:id           "19470756" .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/Shape/a3fcd>
        rdf:type             gpml:shape ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP3630_r138896> ;
        gpml:align           "Center" ;
        gpml:centerX         "718.0"^^xsd:double ;
        gpml:centerY         "458.0"^^xsd:double ;
        gpml:color           "a0a0a0" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "10.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "a3fcd" ;
        gpml:height          "98.0"^^xsd:double ;
        gpml:lineStyle       "Broken" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shape           "0.0"^^xsd:double ;
        gpml:shapeType       "RoundedRectangle" ;
        gpml:textlabel       "" ;
        gpml:valign          "Middle" ;
        gpml:width           "274.0"^^xsd:double ;
        gpml:zorder          "16384"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/d0993/Point/eab1fe18b8da77911cded27965338f9e>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP3630_r138896> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/d0993> ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "584.3286573146293"^^xsd:double ;
        gpml:y            "215.3671974599693"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/idedd953c8/Point/4d9a6f5daea78e32ec265e9a3dcae7a8>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP3630_r138896> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/idedd953c8> ;
        gpml:graphRef     "b2746" ;
        gpml:relX         "1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "290.50866438759806"^^xsd:double ;
        gpml:y            "256.5546218487396"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/id68473c22/Point/9fed4b1e4289be5117c53410e09994ae>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP3630_r138896> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/id68473c22> ;
        gpml:graphRef     "d2ede" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "382.18907563025147"^^xsd:double ;
        gpml:y            "246.5546218487396"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/id647ea175/Point/5a144b0a5d040e00d4de50f155982c69>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP3630_r138896> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/id647ea175> ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "584.3286573146293"^^xsd:double ;
        gpml:y            "172.15207212067116"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/Label/cc0c9>
        rdf:type             gpml:Label ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Group/ac809> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896> ;
        gpml:align           "Center" ;
        gpml:centerX         "736.5963092928189"^^xsd:double ;
        gpml:centerY         "333.1492397671853"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Bold" ;
        gpml:graphId         "cc0c9" ;
        gpml:groupRef        "f00ca" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:href            "" ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "None" ;
        gpml:textlabel       "Liver" ;
        gpml:valign          "Middle" ;
        gpml:width           "108.0"^^xsd:double ;
        gpml:zorder          "32797"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/a4271/Point/dffaf95d6d30f8732a052d2c0e548d25>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP3630_r138896> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/a4271> ;
        gpml:graphRef     "d3b0f" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "624.6579359417424"^^xsd:double ;
        gpml:y            "185.83830020950992"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/DataNode/ef291>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP3630_r138896> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Group/aa34f> ;
        gpml:align           "Center" ;
        gpml:centerX         "654.6579359417425"^^xsd:double ;
        gpml:centerY         "161.85433227363805"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "10.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "ef291" ;
        gpml:groupRef        "e3706" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "FOXO1" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "60.0"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000150907" ;
        gpml:zorder          "32768"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/Label/ee4bb>
        rdf:type             gpml:Label ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Group/ac809> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896> ;
        gpml:align           "Center" ;
        gpml:centerX         "785.0365268351838"^^xsd:double ;
        gpml:centerY         "349.1488691669054"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "10.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "ee4bb" ;
        gpml:groupRef        "f00ca" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:href            "" ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "None" ;
        gpml:textlabel       "Decreased insulin sensitivity " ;
        gpml:valign          "Middle" ;
        gpml:width           "149.2436974789917"^^xsd:double ;
        gpml:zorder          "32800"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/ide61fe032>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP3630_r138896> ;
        gpml:color          "0" ;
        gpml:connectorType  "Elbow" ;
        gpml:graphId        "ide61fe032" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/ide61fe032/Point/abbe7c3cc24704439bd05bc140af6c29> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/ide61fe032/Point/51d28491277458fbe1fa2043d5db3d45> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/idd9b01f7>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP3630_r138896> ;
        gpml:color          "ff9900" ;
        gpml:connectorType  "Elbow" ;
        gpml:graphId        "idd9b01f7" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/idd9b01f7/Point/e93c6510633a9fecde87080ef20ec4c2> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/idd9b01f7/Point/ddd54ef53264bf3c6e316d8841b75e68> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/idd9b01f7/Point/3f51288218ba4c8781c73f8e5739ff6c> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<https://identifiers.org/pubmed/16628003>
        rdf:type          gpml:PublicationXref ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/iddb37003a> ;
        gpml:database     "Pubmed" ;
        gpml:id           "16628003" .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/GraphicalLine/idf1dfc86b/Point/572f71452b4fb16ebba7cece63515a4f>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP3630_r138896> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/GraphicalLine/idf1dfc86b> ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "591.0336134453783"^^xsd:double ;
        gpml:y            "453.1254610060455"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/GraphicalLine/ecc52/Point/725c5fd4c990333b252170cc4d4e59b3>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP3630_r138896> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/GraphicalLine/ecc52> ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "649.4733893557421"^^xsd:double ;
        gpml:y            "473.1254610060455"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/DataNode/fe4a5>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP3630_r138896> ;
        gpml:align           "Center" ;
        gpml:centerX         "93.0"^^xsd:double ;
        gpml:centerY         "404.0"^^xsd:double ;
        gpml:color           "ff" ;
        gpml:fillColor       "ffdddd" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "fe4a5" ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "RoundedRectangle" ;
        gpml:textlabel       "Ataxia telangiectasia" ;
        gpml:type            "Unknown" ;
        gpml:valign          "Middle" ;
        gpml:width           "150.0"^^xsd:double ;
        gpml:xrefDataSource  "Wikidata" ;
        gpml:xrefId          "Q387082" ;
        gpml:zorder          "32814"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/idb0edb154>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP3630_r138896> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "idb0edb154" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/idb0edb154/Point/1ed081588ff9b56e2381d90acbff3236> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/idb0edb154/Point/eba1de28f5174788c51a8ec899562bbf> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/e2982>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP3630_r138896> ;
        gpml:color          "cc0066" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "e2982" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/e2982/Point/43039df2212c681e38f9824d33b2de66> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/e2982/Point/1797fdd1848738bed129019640e6ae74> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "32791"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/a4271/Point/f596ddbca609bd72774029fbf718a5d>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP3630_r138896> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/a4271> ;
        gpml:graphRef     "b74eb" ;
        gpml:relX         "1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "412.1890756302514"^^xsd:double ;
        gpml:y            "149.4789915966383"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/d0993/Point/6833ea167c272e9411685b9f1affdf78>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP3630_r138896> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/d0993> ;
        gpml:graphRef     "aa34f" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "616.6579359417424"^^xsd:double ;
        gpml:y            "210.53057551642632"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/ae3ab/Point/eff6399ef6011a9d2454947df770dc38>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP3630_r138896> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/ae3ab> ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "441.7983193277315"^^xsd:double ;
        gpml:y            "302.876955591856"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/ide7a6c22>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP3630_r138896> ;
        gpml:color          "cc0066" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "ide7a6c22" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/ide7a6c22/Point/66c40335250bcbb840a6735c5ac5bc63> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/ide7a6c22/Point/2ff6cb254f4d58bfa646637b27304bf2> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/a1de6/Point/fbab06ea23cdb90ef8417f3650f4f041>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP3630_r138896> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/a1de6> ;
        gpml:graphRef     "a1e1d" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "352.36974789915905"^^xsd:double ;
        gpml:y            "370.9339350970843"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/id647ea175/Point/8f366908d858f6ea146c643ebfcf4f3>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP3630_r138896> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/id647ea175> ;
        gpml:graphRef     "b1532" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "624.4561718844093"^^xsd:double ;
        gpml:y            "124.10032483783007"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/Label/c9fc9>
        rdf:type             gpml:Label ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Group/ac809> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896> ;
        gpml:align           "Center" ;
        gpml:centerX         "783.9440898603939"^^xsd:double ;
        gpml:centerY         "219.9051716879137"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "10.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "c9fc9" ;
        gpml:groupRef        "f00ca" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:href            "" ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "None" ;
        gpml:textlabel       "Decreased cognitive function" ;
        gpml:valign          "Middle" ;
        gpml:width           "149.2436974789917"^^xsd:double ;
        gpml:zorder          "32798"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/idd9b01f7/Point/ddd54ef53264bf3c6e316d8841b75e68>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP3630_r138896> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/idd9b01f7> ;
        gpml:graphRef     "bdb6e" ;
        gpml:relX         "1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "538.0832589548863"^^xsd:double ;
        gpml:y            "349.1992893349725"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/Label/f838c>
        rdf:type             gpml:Label ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP3630_r138896> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Group/ac809> ;
        gpml:align           "Left" ;
        gpml:centerX         "778.161120560449"^^xsd:double ;
        gpml:centerY         "286.52702042740947"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "10.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "f838c" ;
        gpml:groupRef        "f00ca" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:href            "" ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "None" ;
        gpml:textlabel       "Decreased mitochondrial\nfunction" ;
        gpml:valign          "Middle" ;
        gpml:width           "125.67775887910193"^^xsd:double ;
        gpml:zorder          "32799"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/idedd953c8/Point/393822f214e75c940a2a7e283a764efa>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP3630_r138896> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/idedd953c8> ;
        gpml:graphRef     "d2ede" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "353.18907563025147"^^xsd:double ;
        gpml:y            "256.5546218487396"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/iddb37003a/Point/2e438e43589bf8701f115178890ad8f1>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP3630_r138896> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/iddb37003a> ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "445.2507115070471"^^xsd:double ;
        gpml:y            "420.08403361344534"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/idba629f1a>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP3630_r138896> ;
        gpml:color          "0" ;
        gpml:connectorType  "Elbow" ;
        gpml:graphId        "idba629f1a" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/idba629f1a/Point/183efa6c796d14446c6c9253ccecbc70> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/idba629f1a/Point/d2c9dba13917a728aad556c931edb3cf> ;
        gpml:lineStyle      "Broken" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/idedd953c8>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP3630_r138896> ;
        gpml:color          "cc0066" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "idedd953c8" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/idedd953c8/Point/4d9a6f5daea78e32ec265e9a3dcae7a8> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/idedd953c8/Point/393822f214e75c940a2a7e283a764efa> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/id3c940720>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP3630_r138896> ;
        gpml:color          "0" ;
        gpml:connectorType  "Elbow" ;
        gpml:graphId        "id3c940720" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/id3c940720/Point/cc13397e8040cba488d9ef2e97c0373d> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/id3c940720/Point/6a19675137b9a499bec0897cc9b34117> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/id3c940720/Point/da6960ae29fc27bd06a0cf118544687c> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/DataNode/b2746>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP3630_r138896> ;
        gpml:align           "Center" ;
        gpml:centerX         "230.00866438759806"^^xsd:double ;
        gpml:centerY         "256.5546218487396"^^xsd:double ;
        gpml:color           "ff" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "10.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "b2746" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "Nicotinamide riboside" ;
        gpml:type            "Metabolite" ;
        gpml:valign          "Middle" ;
        gpml:width           "121.0"^^xsd:double ;
        gpml:xrefDataSource  "HMDB" ;
        gpml:xrefId          "HMDB0000855" ;
        gpml:zorder          "32768"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/idb53f1655/Point/795377ad664f8df538a808b3b597a722>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP3630_r138896> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/idb53f1655> ;
        gpml:graphRef     "ccb75" ;
        gpml:relX         "1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "168.0"^^xsd:double ;
        gpml:y            "338.0"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/GraphicalLine/idf1dfc86b/Point/fcc56f36d984f63329710f4116d2ae97>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP3630_r138896> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/GraphicalLine/idf1dfc86b> ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "648.8067226890757"^^xsd:double ;
        gpml:y            "453.1254610060455"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/DataNode/e570f>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Group/aa34f> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896> ;
        gpml:align           "Center" ;
        gpml:centerX         "654.6579359417424"^^xsd:double ;
        gpml:centerY         "259.20681875921457"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "10.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "e570f" ;
        gpml:groupRef        "e3706" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "PPARG" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "60.0"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000132170" ;
        gpml:zorder          "32778"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/iddb37003a/Point/53b07c85dfa2d58118444c5b51c8c0d3>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP3630_r138896> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/iddb37003a> ;
        gpml:graphRef     "a1e1d" ;
        gpml:relX         "0.5"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "397.36974789915905"^^xsd:double ;
        gpml:y            "380.9339350970843"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/e67d5>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP3630_r138896> ;
        gpml:color          "cc0066" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "e67d5" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/e67d5/Point/c20641eda94c56ed6243dfc7ba6db7ff> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/e67d5/Point/68f55b6083ca0326392b872b1405af94> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "32789"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/id647ea175>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP3630_r138896> ;
        gpml:color          "ff9900" ;
        gpml:connectorType  "Elbow" ;
        gpml:graphId        "id647ea175" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/id647ea175/Point/e59e89ca1c259172ecbf48949b0f6591> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/id647ea175/Point/8f366908d858f6ea146c643ebfcf4f3> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/id647ea175/Point/5a144b0a5d040e00d4de50f155982c69> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/id1549585d/Point/89308f98e2e353dc317f20fa3f666e5e>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP3630_r138896> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/id1549585d> ;
        gpml:graphRef     "d2ede" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "382.18907563025147"^^xsd:double ;
        gpml:y            "266.5546218487396"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/b1f69>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP3630_r138896> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "b1f69" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/b1f69/Point/e152776e0b695612e17e4d3970394af8> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/b1f69/Point/4dee1c60801324531078738ca2b1f335> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "32772"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/df457/Point/c1845f7ecdfcfc642f541842acdea1d>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP3630_r138896> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/df457> ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "579.3186372745491"^^xsd:double ;
        gpml:y            "340.13630950299927"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/e2982/Point/43039df2212c681e38f9824d33b2de66>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP3630_r138896> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/e2982> ;
        gpml:graphRef     "a1e1d" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "382.36974789915905"^^xsd:double ;
        gpml:y            "380.9339350970843"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/Label/c67fd>
        rdf:type             gpml:Label ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP3630_r138896> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Group/ac809> ;
        gpml:align           "Center" ;
        gpml:centerX         "735.5038723180296"^^xsd:double ;
        gpml:centerY         "203.90554228819377"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Bold" ;
        gpml:graphId         "c67fd" ;
        gpml:groupRef        "f00ca" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:href            "" ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "None" ;
        gpml:textlabel       "Brain" ;
        gpml:valign          "Middle" ;
        gpml:width           "108.0"^^xsd:double ;
        gpml:zorder          "32795"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/idb53f1655/Point/504774b395c7527a886ef2f8eb3a0143>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP3630_r138896> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/idb53f1655> ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "188.0"^^xsd:double ;
        gpml:y            "354.3955389771137"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/GraphicalLine/dbb6f>
        rdf:type            gpml:GraphicalLine ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP3630_r138896> ;
        gpml:color          "ff9900" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "dbb6f" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP3630_r138896/GraphicalLine/dbb6f/Point/f91ed5918d31a0bfcc7f5378d8ff1cf3> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/GraphicalLine/dbb6f/Point/b35bbbfb7ff1fffd5e9ab8dbdfda3a8d> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "2.0"^^xsd:double ;
        gpml:zorder         "32811"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/idf1fbe4ee/Point/5679a96f2bb692a149b4fd94fb787360>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP3630_r138896> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/idf1fbe4ee> ;
        gpml:graphRef     "f5a65" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "232.2773109243704"^^xsd:double ;
        gpml:y            "139.53781512605036"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/GraphicalLine/ecc52/Point/fe09bcc65c8a6540a77973c1e31fc950>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP3630_r138896> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/GraphicalLine/ecc52> ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "591.7002801120447"^^xsd:double ;
        gpml:y            "473.1254610060455"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/DataNode/fa463>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Group/aa34f> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896> ;
        gpml:align           "Center" ;
        gpml:centerX         "654.6579359417424"^^xsd:double ;
        gpml:centerY         "235.2128307832627"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "10.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "fa463" ;
        gpml:groupRef        "e3706" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "TORC2" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "60.0"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000108064" ;
        gpml:zorder          "32777"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/DataNode/fc541>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP3630_r138896> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Group/bdc90> ;
        gpml:align           "Center" ;
        gpml:centerX         "654.4561718844093"^^xsd:double ;
        gpml:centerY         "342.6244318754348"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "10.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "fc541" ;
        gpml:groupRef        "b6348" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "HIF1A" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "60.0"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000100644" ;
        gpml:zorder          "32768"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/id3c940720/Point/6a19675137b9a499bec0897cc9b34117>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP3630_r138896> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/id3c940720> ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "441.7983193277315"^^xsd:double ;
        gpml:y            "238.37922062612594"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/Comment/25645da7cc0def1f341d781bf329a280>
        rdf:type          gpml:Comment ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP3630_r138896/DataNode/d367c> ;
        gpml:commentText  "Identifier of Olaparib (known approved PARP inhibitor)" .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/Label/e5fe5>
        rdf:type             gpml:Label ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP3630_r138896> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Group/ac809> ;
        gpml:align           "Center" ;
        gpml:centerX         "773.5029133898058"^^xsd:double ;
        gpml:centerY         "365.3673565618632"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "10.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "e5fe5" ;
        gpml:groupRef        "f00ca" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:href            "" ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "None" ;
        gpml:textlabel       "Increased inflammation" ;
        gpml:valign          "Middle" ;
        gpml:width           "116.68067226890754"^^xsd:double ;
        gpml:zorder          "28672"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/ide61fe032/Point/51d28491277458fbe1fa2043d5db3d45>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP3630_r138896> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/ide61fe032> ;
        gpml:graphRef     "fe4a5" ;
        gpml:relX         "1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "168.0"^^xsd:double ;
        gpml:y            "404.0"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/ae3ab>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP3630_r138896> ;
        gpml:color          "0" ;
        gpml:connectorType  "Elbow" ;
        gpml:graphId        "ae3ab" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/ae3ab/Point/90add8addc6a74b02c177171977fb09f> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/ae3ab/Point/eff6399ef6011a9d2454947df770dc38> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/ae3ab/Point/fce0343460a8f27d9aa7232526b25d2e> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "32792"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/Group/aa34f>
        rdf:type          gpml:Group ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP3630_r138896> ;
        gpml:graphId      "aa34f" ;
        gpml:groupId      "e3706" ;
        gpml:style        "Group" .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/GraphicalLine/dbb6f/Point/f91ed5918d31a0bfcc7f5378d8ff1cf3>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP3630_r138896> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/GraphicalLine/dbb6f> ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "592.3669467787109"^^xsd:double ;
        gpml:y            "494.4587943393791"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/DataNode/d9a24>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP3630_r138896> ;
        gpml:align           "Center" ;
        gpml:centerX         "93.0"^^xsd:double ;
        gpml:centerY         "371.0"^^xsd:double ;
        gpml:color           "ff" ;
        gpml:fillColor       "ffdddd" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "d9a24" ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "RoundedRectangle" ;
        gpml:textlabel       "Xeroderma pigmentosum" ;
        gpml:type            "Unknown" ;
        gpml:valign          "Middle" ;
        gpml:width           "150.0"^^xsd:double ;
        gpml:xrefDataSource  "Wikidata" ;
        gpml:xrefId          "Q612693" ;
        gpml:zorder          "32813"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/GraphicalLine/idf1dfc86b>
        rdf:type            gpml:GraphicalLine ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP3630_r138896> ;
        gpml:color          "cc0066" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "idf1dfc86b" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP3630_r138896/GraphicalLine/idf1dfc86b/Point/fcc56f36d984f63329710f4116d2ae97> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/GraphicalLine/idf1dfc86b/Point/572f71452b4fb16ebba7cece63515a4f> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "2.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/Label/d538c>
        rdf:type             gpml:Label ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP3630_r138896> ;
        gpml:align           "Center" ;
        gpml:centerX         "263.57744059547673"^^xsd:double ;
        gpml:centerY         "370.7910779542274"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Bold" ;
        gpml:graphId         "d538c" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:href            "" ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "None" ;
        gpml:textlabel       "DNA damage" ;
        gpml:valign          "Middle" ;
        gpml:width           "96.0"^^xsd:double ;
        gpml:zorder          "28674"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/id51a6de8f/Point/97b6d8f4be3056556197fb5410447e25>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP3630_r138896> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/id51a6de8f> ;
        gpml:graphRef     "f83b2" ;
        gpml:relX         "1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "178.60645661070077"^^xsd:double ;
        gpml:y            "297.05882352941245"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/Label/f8e4b>
        rdf:type             gpml:Label ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP3630_r138896> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Group/ac809> ;
        gpml:align           "Center" ;
        gpml:centerX         "779.1961907007301"^^xsd:double ;
        gpml:centerY         "155.2833229484179"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "10.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "f8e4b" ;
        gpml:groupRef        "f00ca" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:href            "" ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "None" ;
        gpml:textlabel       "Decreased insulin secretion" ;
        gpml:valign          "Middle" ;
        gpml:width           "149.2436974789917"^^xsd:double ;
        gpml:zorder          "28672"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/d0993/Point/e050aeb4a24feb91129b2694366e6aee>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP3630_r138896> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/d0993> ;
        gpml:graphRef     "d9366" ;
        gpml:relX         "1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "538.1316751149351"^^xsd:double ;
        gpml:y            "220.20381940351228"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896>
        rdfs:seeAlso           <https://www.wikipathways.org/instance/WP3630_r138896> ;
        gpml:author            "[Khanspers, Susan, AlexanderPico, Jmelius, Mkutmon, MaintBot, Eweitz]" ;
        gpml:biopaxRef         "f2f" ;
        gpml:boardHeight       "537.0"^^xsd:double ;
        gpml:boardWidth        "889.6583755746797"^^xsd:double ;
        gpml:data-Source       "WikiPathways" ;
        gpml:hasDataNode       <http://rdf.wikipathways.org/Pathway/WP3630_r138896/DataNode/ef291> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/DataNode/fc541> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/DataNode/abfa0> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/DataNode/d2ede> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/DataNode/ccb75> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/DataNode/f3fd2> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/DataNode/bdb6e> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/DataNode/a1e1d> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/DataNode/c0187> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/DataNode/e570f> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/DataNode/d9366> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/DataNode/fa463> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/DataNode/d3b0f> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/DataNode/e2d46> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/DataNode/c0597> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/DataNode/b74eb> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/DataNode/b2746> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/DataNode/fe4a5> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/DataNode/d367c> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/DataNode/d9a24> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/DataNode/b1532> ;
        gpml:hasGraphicalLine  <http://rdf.wikipathways.org/Pathway/WP3630_r138896/GraphicalLine/dbb6f> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/GraphicalLine/ecc52> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/GraphicalLine/idf1dfc86b> ;
        gpml:hasGroup          <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Group/aa34f> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Group/bdc90> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Group/ac809> ;
        gpml:hasInfoBox        <http://rdf.wikipathways.org/Pathway/WP3630_r138896/InfoBox/381850be4a39ad9b2d9c46eb09698a8a> ;
        gpml:hasInteraction    <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/id3c940720> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/id1947cd81> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/d0993> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/ae3ab> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/iddb37003a> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/id51a6de8f> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/id68473c22> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/b1f69> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/idb53f1655> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/a4271> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/df457> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/idd9b01f7> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/idb0edb154> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/ide61fe032> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/idba629f1a> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/e67d5> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/idf1fbe4ee> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/e2982> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/a1de6> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/ide7a6c22> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/id1549585d> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/id647ea175> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/idedd953c8> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/e4cc8> ;
        gpml:hasLabel          <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Label/c9fc9> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Label/a6c43> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Label/e5fe5> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Label/d538c> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Label/f7ef6> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Label/ad499> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Label/f7b0f> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Label/f5a65> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Label/dbf57> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Label/c67fd> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Label/d49ba> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Label/f8e4b> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Label/ca320> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Label/f83b2> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Label/cc0c9> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Label/f838c> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Label/ee4bb> ;
        gpml:hasShape          <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Shape/a3fcd> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Shape/e4ccf> ;
        gpml:last-Modified     "20250507001853" ;
        gpml:name              "NAD metabolism, sirtuins and aging" ;
        gpml:organism          "Homo sapiens" ;
        gpml:version           "WP3630_r138896" .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/Label/dbf57>
        rdf:type             gpml:Label ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP3630_r138896> ;
        gpml:align           "Center" ;
        gpml:centerX         "749.2394957983194"^^xsd:double ;
        gpml:centerY         "454.17588117411265"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "dbf57" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:href            "" ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "None" ;
        gpml:textlabel       "Possible therapeutic intervention" ;
        gpml:valign          "Middle" ;
        gpml:width           "217.52100840336084"^^xsd:double ;
        gpml:zorder          "28672"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/idba629f1a/Point/d2c9dba13917a728aad556c931edb3cf>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP3630_r138896> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/idba629f1a> ;
        gpml:graphRef     "ef291" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "624.6579359417425"^^xsd:double ;
        gpml:y            "161.85433227363805"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/ide61fe032/Point/abbe7c3cc24704439bd05bc140af6c29>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP3630_r138896> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/ide61fe032> ;
        gpml:graphRef     "d538c" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "215.57744059547673"^^xsd:double ;
        gpml:y            "370.7910779542274"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/InfoBox/381850be4a39ad9b2d9c46eb09698a8a>
        rdf:type          gpml:InfoBox ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP3630_r138896> ;
        gpml:centerX      "0.0"^^xsd:double ;
        gpml:centerY      "0.0"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/DataNode/f3fd2>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP3630_r138896> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Group/bdc90> ;
        gpml:align           "Center" ;
        gpml:centerX         "654.4561718844094"^^xsd:double ;
        gpml:centerY         "319.5222274666173"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "10.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "f3fd2" ;
        gpml:groupRef        "b6348" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "ROS1" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "60.0"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000047936" ;
        gpml:zorder          "32774"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/e67d5/Point/68f55b6083ca0326392b872b1405af94>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP3630_r138896> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/e67d5> ;
        gpml:graphRef     "b74eb" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "382.1890756302514"^^xsd:double ;
        gpml:y            "139.4789915966383"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/id51a6de8f/Point/f99e799cfdf214acd8e9e3d2ee03478e>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP3630_r138896> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/id51a6de8f> ;
        gpml:graphRef     "d538c" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "263.57744059547673"^^xsd:double ;
        gpml:y            "360.7910779542274"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/id68473c22/Point/783778a72037d897202b7a894636df1>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP3630_r138896> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/id68473c22> ;
        gpml:graphRef     "b74eb" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "382.1890756302514"^^xsd:double ;
        gpml:y            "159.4789915966383"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/DataNode/d2ede>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP3630_r138896> ;
        gpml:align           "Center" ;
        gpml:centerX         "382.18907563025147"^^xsd:double ;
        gpml:centerY         "256.5546218487396"^^xsd:double ;
        gpml:color           "ff" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "10.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "d2ede" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "NAD" ;
        gpml:type            "Metabolite" ;
        gpml:valign          "Middle" ;
        gpml:width           "58.0"^^xsd:double ;
        gpml:xrefDataSource  "HMDB" ;
        gpml:xrefId          "HMDB0000902" ;
        gpml:zorder          "32768"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/e4cc8/Point/8b94c069feb24a28d87ac9e05d356f15>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP3630_r138896> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/e4cc8> ;
        gpml:graphRef     "d9366" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "508.1316751149351"^^xsd:double ;
        gpml:y            "230.20381940351228"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/ae3ab/Point/90add8addc6a74b02c177171977fb09f>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP3630_r138896> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/ae3ab> ;
        gpml:graphRef     "d2ede" ;
        gpml:relX         "1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "411.18907563025147"^^xsd:double ;
        gpml:y            "256.5546218487396"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/DataNode/c0187>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP3630_r138896> ;
        gpml:align           "Center" ;
        gpml:centerX         "382.1890756302514"^^xsd:double ;
        gpml:centerY         "99.60504201680672"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "10.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "c0187" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "P7C3" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "60.0"^^xsd:double ;
        gpml:xrefDataSource  "" ;
        gpml:xrefId          "" ;
        gpml:zorder          "32768"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/a1de6>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP3630_r138896> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "a1de6" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/a1de6/Point/fbab06ea23cdb90ef8417f3650f4f041> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/a1de6/Point/4b829d51c096d627dd2fdcc2d4531bd0> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "32771"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/id647ea175/Point/e59e89ca1c259172ecbf48949b0f6591>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP3630_r138896> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/id647ea175> ;
        gpml:graphRef     "d9366" ;
        gpml:relX         "1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "538.1316751149351"^^xsd:double ;
        gpml:y            "220.20381940351228"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/a1de6/Point/4b829d51c096d627dd2fdcc2d4531bd0>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP3630_r138896> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/a1de6> ;
        gpml:graphRef     "d538c" ;
        gpml:relX         "1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "311.57744059547673"^^xsd:double ;
        gpml:y            "370.7910779542274"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/idb53f1655>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP3630_r138896> ;
        gpml:color          "0" ;
        gpml:connectorType  "Elbow" ;
        gpml:graphId        "idb53f1655" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/idb53f1655/Point/504774b395c7527a886ef2f8eb3a0143> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/idb53f1655/Point/795377ad664f8df538a808b3b597a722> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/idb53f1655/Point/e99455dd85e40a8cf5417d08ee3c7620> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/idf1fbe4ee/Point/57357f603b553323f3e2f7d024b6c018>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP3630_r138896> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/idf1fbe4ee> ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "443.3667414043898"^^xsd:double ;
        gpml:y            "72.0"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/DataNode/b1532>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP3630_r138896> ;
        gpml:align           "Center" ;
        gpml:centerX         "654.4561718844093"^^xsd:double ;
        gpml:centerY         "124.10032483783007"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "10.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "b1532" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "NFKB1" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "60.0"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000109320" ;
        gpml:zorder          "32768"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/GraphicalLine/ecc52>
        rdf:type            gpml:GraphicalLine ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP3630_r138896> ;
        gpml:color          "9999" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "ecc52" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP3630_r138896/GraphicalLine/ecc52/Point/fe09bcc65c8a6540a77973c1e31fc950> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/GraphicalLine/ecc52/Point/725c5fd4c990333b252170cc4d4e59b3> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "2.0"^^xsd:double ;
        gpml:zorder         "32810"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/idd9b01f7/Point/3f51288218ba4c8781c73f8e5739ff6c>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP3630_r138896> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/idd9b01f7> ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "579.3186372745491"^^xsd:double ;
        gpml:y            "363.24752955272646"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/GraphicalLine/dbb6f/Point/b35bbbfb7ff1fffd5e9ab8dbdfda3a8d>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP3630_r138896> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/GraphicalLine/dbb6f> ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "650.1400560224084"^^xsd:double ;
        gpml:y            "494.4587943393791"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/d0993>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP3630_r138896> ;
        gpml:color          "ff9900" ;
        gpml:connectorType  "Elbow" ;
        gpml:graphId        "d0993" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/d0993/Point/e050aeb4a24feb91129b2694366e6aee> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/d0993/Point/eab1fe18b8da77911cded27965338f9e> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/d0993/Point/6833ea167c272e9411685b9f1affdf78> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "32801"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/ide7a6c22/Point/66c40335250bcbb840a6735c5ac5bc63>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP3630_r138896> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/ide7a6c22> ;
        gpml:graphRef     "e2d46" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "523.0"^^xsd:double ;
        gpml:y            "182.50918644010656"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/DataNode/abfa0>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP3630_r138896> ;
        gpml:align           "Center" ;
        gpml:centerX         "654.4561718844092"^^xsd:double ;
        gpml:centerY         "377.29576977048043"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "10.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "abfa0" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "TFAM" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "60.0"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000108064" ;
        gpml:zorder          "32768"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/DataNode/e2d46>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP3630_r138896> ;
        gpml:align           "Center" ;
        gpml:centerX         "523.0"^^xsd:double ;
        gpml:centerY         "172.50918644010656"^^xsd:double ;
        gpml:color           "ff" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "10.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "e2d46" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "Resveratrol" ;
        gpml:type            "Metabolite" ;
        gpml:valign          "Middle" ;
        gpml:width           "80.0"^^xsd:double ;
        gpml:xrefDataSource  "CAS" ;
        gpml:xrefId          "501-36-0" ;
        gpml:zorder          "32768"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/Label/d49ba>
        rdf:type             gpml:Label ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP3630_r138896> ;
        gpml:align           "Center" ;
        gpml:centerX         "91.93277310924367"^^xsd:double ;
        gpml:centerY         "149.53781512605022"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Bold" ;
        gpml:graphId         "d49ba" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:href            "" ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "None" ;
        gpml:textlabel       "High-fat diet" ;
        gpml:valign          "Middle" ;
        gpml:width           "96.0"^^xsd:double ;
        gpml:zorder          "28672"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/Label/f7ef6>
        rdf:type             gpml:Label ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP3630_r138896> ;
        gpml:align           "Center" ;
        gpml:centerX         "718.5963092928189"^^xsd:double ;
        gpml:centerY         "425.1492397671853"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "14.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Bold" ;
        gpml:graphId         "f7ef6" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:href            "" ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "None" ;
        gpml:textlabel       "Legend" ;
        gpml:valign          "Middle" ;
        gpml:width           "108.0"^^xsd:double ;
        gpml:zorder          "32812"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/idb0edb154/Point/eba1de28f5174788c51a8ec899562bbf>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP3630_r138896> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/idb0edb154> ;
        gpml:graphRef     "f5a65" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "184.2773109243704"^^xsd:double ;
        gpml:y            "149.53781512605036"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/Group/bdc90>
        rdf:type          gpml:Group ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP3630_r138896> ;
        gpml:graphId      "bdc90" ;
        gpml:groupId      "b6348" ;
        gpml:style        "Group" .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/e67d5/Point/c20641eda94c56ed6243dfc7ba6db7ff>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP3630_r138896> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/e67d5> ;
        gpml:graphRef     "c0187" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "382.1890756302514"^^xsd:double ;
        gpml:y            "109.60504201680672"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/id1549585d>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP3630_r138896> ;
        gpml:color          "9999" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "id1549585d" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/id1549585d/Point/89308f98e2e353dc317f20fa3f666e5e> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/id1549585d/Point/9f13d9849e5632d18ae8ae877f04519f> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/Shape/e4ccf>
        rdf:type             gpml:shape ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Group/ac809> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896> ;
        gpml:align           "Center" ;
        gpml:centerX         "782.2052382075083"^^xsd:double ;
        gpml:centerY         "252.26351021370482"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "10.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "e4ccf" ;
        gpml:groupRef        "f00ca" ;
        gpml:height          "270.52702042740964"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shape           "0.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "" ;
        gpml:valign          "Middle" ;
        gpml:width           "145.58952358498345"^^xsd:double ;
        gpml:zorder          "16384"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/a4271>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP3630_r138896> ;
        gpml:color          "0" ;
        gpml:connectorType  "Elbow" ;
        gpml:graphId        "a4271" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/a4271/Point/f596ddbca609bd72774029fbf718a5d> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/a4271/Point/dffaf95d6d30f8732a052d2c0e548d25> ;
        gpml:lineStyle      "Broken" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "32809"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/e4cc8/Point/8790f516c7a6e62ac582bf70899eec8a>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP3630_r138896> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/e4cc8> ;
        gpml:graphRef     "d538c" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "263.57744059547673"^^xsd:double ;
        gpml:y            "380.7910779542274"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/DataNode/ccb75>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP3630_r138896> ;
        gpml:align           "Center" ;
        gpml:centerX         "93.0"^^xsd:double ;
        gpml:centerY         "338.0"^^xsd:double ;
        gpml:color           "ff" ;
        gpml:fillColor       "ffdddd" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "ccb75" ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "RoundedRectangle" ;
        gpml:textlabel       "Cockayne syndrome" ;
        gpml:type            "Unknown" ;
        gpml:valign          "Middle" ;
        gpml:width           "150.0"^^xsd:double ;
        gpml:xrefDataSource  "Wikidata" ;
        gpml:xrefId          "Q914389" ;
        gpml:zorder          "32768"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/df457>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP3630_r138896> ;
        gpml:color          "ff9900" ;
        gpml:connectorType  "Elbow" ;
        gpml:graphId        "df457" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/df457/Point/c1845f7ecdfcfc642f541842acdea1d> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/df457/Point/17ece6d7131461bf9a8c714950f48eed> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/df457/Point/7fa56b6715d26a66efc5044d86a3d659> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "32802"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/idba629f1a/Point/183efa6c796d14446c6c9253ccecbc70>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP3630_r138896> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/idba629f1a> ;
        gpml:graphRef     "b74eb" ;
        gpml:relX         "1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "412.1890756302514"^^xsd:double ;
        gpml:y            "149.4789915966383"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/idb53f1655/Point/e99455dd85e40a8cf5417d08ee3c7620>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP3630_r138896> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/idb53f1655> ;
        gpml:graphRef     "d538c" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "215.57744059547673"^^xsd:double ;
        gpml:y            "370.7910779542274"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/Group/ac809>
        rdf:type          gpml:Group ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP3630_r138896> ;
        gpml:graphId      "ac809" ;
        gpml:groupId      "f00ca" ;
        gpml:style        "Group" .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/id3c940720/Point/cc13397e8040cba488d9ef2e97c0373d>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP3630_r138896> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/id3c940720> ;
        gpml:graphRef     "d2ede" ;
        gpml:relX         "1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "411.18907563025147"^^xsd:double ;
        gpml:y            "256.5546218487396"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/e4cc8/Point/30fd8554ccde79ec0c17044434a32e01>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP3630_r138896> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/e4cc8> ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "385.85455785520594"^^xsd:double ;
        gpml:y            "435.0"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/id68473c22>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP3630_r138896> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "id68473c22" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/id68473c22/Point/783778a72037d897202b7a894636df1> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/id68473c22/Point/9fed4b1e4289be5117c53410e09994ae> ;
        gpml:lineStyle      "Broken" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/Label/f7b0f>
        rdf:type             gpml:Label ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP3630_r138896> ;
        gpml:align           "Center" ;
        gpml:centerX         "699.140280561122"^^xsd:double ;
        gpml:centerY         "494.2360014145934"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "f7b0f" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:href            "" ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "None" ;
        gpml:textlabel       "Deacetylation" ;
        gpml:valign          "Middle" ;
        gpml:width           "85.15030060120192"^^xsd:double ;
        gpml:zorder          "32808"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/DataNode/bdb6e>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP3630_r138896> ;
        gpml:align           "Center" ;
        gpml:centerX         "508.08325895488633"^^xsd:double ;
        gpml:centerY         "349.1992893349725"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "10.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "bdb6e" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "SIRT3" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "60.0"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000142082" ;
        gpml:zorder          "32794"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/iddb37003a/Point/6e0a8d43aa2518213fff16c96db46c6a>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP3630_r138896> , <http://rdf.wikipathways.org/Pathway/WP3630_r138896/Interaction/iddb37003a> ;
        gpml:graphRef     "d9366" ;
        gpml:relX         "-0.5"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "493.1316751149351"^^xsd:double ;
        gpml:y            "230.20381940351228"^^xsd:double .
