@prefix biopax:  <http://www.biopax.org/release/biopax-level3.owl#> .
@prefix cito:    <http://purl.org/spar/cito/> .
@prefix dc:      <http://purl.org/dc/elements/1.1/> .
@prefix dcterms: <http://purl.org/dc/terms/> .
@prefix foaf:    <http://xmlns.com/foaf/0.1/> .
@prefix freq:    <http://purl.org/cld/freq/> .
@prefix gpml:    <http://vocabularies.wikipathways.org/gpml#> .
@prefix obo:     <http://purl.obolibrary.org/obo/> .
@prefix owl:     <http://www.w3.org/2002/07/owl#> .
@prefix pav:     <http://purl.org/pav/> .
@prefix prov:    <http://www.w3.org/ns/prov#> .
@prefix rdf:     <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix rdfs:    <http://www.w3.org/2000/01/rdf-schema#> .
@prefix skos:    <http://www.w3.org/2004/02/skos/core#> .
@prefix void:    <http://rdfs.org/ns/void#> .
@prefix wp:      <http://vocabularies.wikipathways.org/wp#> .
@prefix wprdf:   <http://rdf.wikipathways.org/> .
@prefix xsd:     <http://www.w3.org/2001/XMLSchema#> .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Shape/f74c3>
        rdf:type             gpml:shape ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4331_r135060> ;
        gpml:align           "Center" ;
        gpml:centerX         "581.8658960891875"^^xsd:double ;
        gpml:centerY         "106.76037029894974"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "14.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "f74c3" ;
        gpml:height          "55.62106581105604"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "3.0"^^xsd:double ;
        gpml:shape           "0.0"^^xsd:double ;
        gpml:shapeType       "Oval" ;
        gpml:textlabel       "Tip EC" ;
        gpml:valign          "Middle" ;
        gpml:width           "100.86970192460967"^^xsd:double ;
        gpml:zorder          "32795"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/InfoBox/88be47110e11b044fbd4eb7f1eb58f49>
        rdf:type          gpml:InfoBox ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4331_r135060> ;
        gpml:centerX      "0.0"^^xsd:double ;
        gpml:centerY      "0.0"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Shape/f520a>
        rdf:type             gpml:shape ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4331_r135060> ;
        gpml:align           "Center" ;
        gpml:centerX         "69.87222809317751"^^xsd:double ;
        gpml:centerY         "445.30886600394354"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "14.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "f520a" ;
        gpml:height          "55.62106581105604"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "3.0"^^xsd:double ;
        gpml:shape           "0.0"^^xsd:double ;
        gpml:shapeType       "Oval" ;
        gpml:textlabel       "MSC" ;
        gpml:valign          "Middle" ;
        gpml:width           "100.86970192460967"^^xsd:double ;
        gpml:zorder          "32802"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/idc5a379ce/Point/e3632abba3c3601356cd0eadf5dd4256>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4331_r135060> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/idc5a379ce> ;
        gpml:graphRef     "e7903" ;
        gpml:relX         "-0.5"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "915.4047215640462"^^xsd:double ;
        gpml:y            "305.52052257933"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/DataNode/c971a>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Group/c0c97> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060> ;
        gpml:align           "Center" ;
        gpml:centerX         "1169.0607909551402"^^xsd:double ;
        gpml:centerY         "386.97778341870765"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "14.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "c971a" ;
        gpml:groupRef        "a08cd" ;
        gpml:hasComment      <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Comment/fa9a3cb82c9e18a9d1c7c6abfa9018d1> ;
        gpml:height          "28.919703884103914"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "JNK2" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "61.843845920311935"^^xsd:double ;
        gpml:xrefDataSource  "UniProtKB" ;
        gpml:xrefId          "P45984" ;
        gpml:zorder          "32841"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id57bda919/Point/8790f516c7a6e62ac582bf70899eec8a>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4331_r135060> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id57bda919> ;
        gpml:graphRef     "f71c7" ;
        gpml:relX         "1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "931.5136435592428"^^xsd:double ;
        gpml:y            "617.7037392138061"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/DataNode/d8066>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4331_r135060> ;
        gpml:align           "Center" ;
        gpml:centerX         "322.6350233864048"^^xsd:double ;
        gpml:centerY         "780.5618587541657"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "d8066" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "RoundedRectangle" ;
        gpml:textlabel       "Cell differentiation" ;
        gpml:type            "Pathway" ;
        gpml:valign          "Middle" ;
        gpml:width           "165.0119047619046"^^xsd:double ;
        gpml:xrefDataSource  "" ;
        gpml:xrefId          "" ;
        gpml:zorder          "32815"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Shape/d5e47>
        rdf:type             gpml:shape ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4331_r135060> ;
        gpml:align           "Center" ;
        gpml:centerX         "1006.4085220638442"^^xsd:double ;
        gpml:centerY         "516.8202289773849"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "14.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "d5e47" ;
        gpml:height          "55.62106581105604"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "3.0"^^xsd:double ;
        gpml:shape           "0.0"^^xsd:double ;
        gpml:shapeType       "Oval" ;
        gpml:textlabel       "HSC" ;
        gpml:valign          "Middle" ;
        gpml:width           "100.86970192460967"^^xsd:double ;
        gpml:zorder          "16384"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/idc92c6d04/Point/3d7ba9a912ae2f5630210ce51e069e04>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4331_r135060> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/idc92c6d04> ;
        gpml:graphRef     "d4da8" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "693.5853078118374"^^xsd:double ;
        gpml:y            "329.5312251048865"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id7f8471d/Point/ae4b73b61a4b1be506d6f1670c9033d1>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4331_r135060> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id7f8471d> ;
        gpml:graphRef     "b7ea0" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "883.5795040620794"^^xsd:double ;
        gpml:y            "150.4341295640733"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id959f9a3b>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4331_r135060> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "id959f9a3b" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id959f9a3b/Point/5999a36205813a6f52935867a22375a4> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id959f9a3b/Point/a1b9962d2ab7d3115240a41a93e44eee> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/idf5a00189/Point/8aede580e571abbe2daeffe3b52bc571>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4331_r135060> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/idf5a00189> ;
        gpml:graphRef     "ae661" ;
        gpml:relX         "-0.5"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "992.4836135894877"^^xsd:double ;
        gpml:y            "203.3034774475904"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Comment/ef7ecff409e9d8c6f70835ed2854daa9>
        rdf:type          gpml:Comment ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4331_r135060/DataNode/cecc1> ;
        gpml:commentText  "AKA MAPK3" .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id7c08421a/Point/c9c2796182d59e58bae2d64a34df5188>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4331_r135060> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id7c08421a> ;
        gpml:graphRef     "e7903" ;
        gpml:relX         "0.5"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "968.9275862654822"^^xsd:double ;
        gpml:y            "305.52052257933"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/idad1e67e7/Point/3baa0a8cc055dcd9cb62a98a8885224a>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4331_r135060> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/idad1e67e7> ;
        gpml:graphRef     "fbd22" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "-0.5"^^xsd:double ;
        gpml:x            "1086.9059270380988"^^xsd:double ;
        gpml:y            "781.5524809489692"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Group/c0c97>
        rdf:type          gpml:Group ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4331_r135060> ;
        gpml:graphId      "c0c97" ;
        gpml:groupId      "a08cd" ;
        gpml:style        "Group" .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id629ea143/Point/dffaf95d6d30f8732a052d2c0e548d25>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4331_r135060> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id629ea143> ;
        gpml:graphRef     "b8df0" ;
        gpml:relX         "-0.5"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "1152.0920335742796"^^xsd:double ;
        gpml:y            "687.0414983949772"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/ide828ebdd>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4331_r135060> ;
        gpml:color          "0" ;
        gpml:connectorType  "Elbow" ;
        gpml:graphId        "ide828ebdd" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/ide828ebdd/Point/ac156fcf6d52b7a479347e1aefcd5581> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/ide828ebdd/Point/a387153ecbb09e1e1be7cebb7e730bb5> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Group/fbd22>
        rdf:type          gpml:Group ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4331_r135060> ;
        gpml:graphId      "fbd22" ;
        gpml:groupId      "a563a" ;
        gpml:style        "Complex" .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/ida82223d6/Point/3082bb6a0f2f1d76e6e9d998e8145537>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4331_r135060> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/ida82223d6> ;
        gpml:graphRef     "c532b" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "1393.0045827887452"^^xsd:double ;
        gpml:y            "505.52048605050095"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/DataNode/b09b3>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4331_r135060> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Group/f47e2> ;
        gpml:align           "Center" ;
        gpml:centerX         "1281.168831168831"^^xsd:double ;
        gpml:centerY         "616.0606060606054"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "b09b3" ;
        gpml:groupRef        "b91c5" ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "NFKB2" ;
        gpml:type            "Protein" ;
        gpml:valign          "Middle" ;
        gpml:width           "90.0"^^xsd:double ;
        gpml:xrefDataSource  "UniProtKB" ;
        gpml:xrefId          "Q00653" ;
        gpml:zorder          "32846"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id7f8471d>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4331_r135060> ;
        gpml:color          "0" ;
        gpml:connectorType  "Elbow" ;
        gpml:graphId        "id7f8471d" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id7f8471d/Point/c1fcedeff16048c020bf6dddfa66d0e8> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id7f8471d/Point/ae4b73b61a4b1be506d6f1670c9033d1> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id9620c5fe/Point/ac1ce30a3eae07dc2c991d3c7de4cda7>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4331_r135060> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id9620c5fe> ;
        gpml:graphRef     "b037b" ;
        gpml:relX         "-0.5"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "1331.0957154786233"^^xsd:double ;
        gpml:y            "401.4944645068202"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id9673afb8>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4331_r135060> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "id9673afb8" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id9673afb8/Point/ee3a4787fb41c028923469f78cae30fe> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id9673afb8/Point/82353ab490b96b17ee850f378acca0a1> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/DataNode/da088>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4331_r135060> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Group/f71c7> ;
        gpml:align           "Center" ;
        gpml:centerX         "869.9907788578068"^^xsd:double ;
        gpml:centerY         "601.2253958040445"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "14.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "da088" ;
        gpml:groupRef        "d4da1" ;
        gpml:height          "26.849304269187257"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "ANGPT1" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "107.04572940287215"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000154188" ;
        gpml:zorder          "32810"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Shape/f402d>
        rdf:type             gpml:shape ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4331_r135060> ;
        gpml:align           "Center" ;
        gpml:centerX         "341.07685309317424"^^xsd:double ;
        gpml:centerY         "379.58673475394505"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "14.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "f402d" ;
        gpml:height          "55.62106581105604"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "3.0"^^xsd:double ;
        gpml:shape           "0.0"^^xsd:double ;
        gpml:shapeType       "Oval" ;
        gpml:textlabel       "EPC" ;
        gpml:valign          "Middle" ;
        gpml:width           "100.86970192460967"^^xsd:double ;
        gpml:zorder          "32804"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id56380431/Point/fd0d9312a9d5e5bf203a70c04fd8e06e>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4331_r135060> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id56380431> ;
        gpml:graphRef     "c0c97" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "1169.4929430726856"^^xsd:double ;
        gpml:y            "219.9194120561359"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/ide74fcb2f/Point/47892db9c36e660fc38bd4f9bdb1a266>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4331_r135060> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/ide74fcb2f> ;
        gpml:graphRef     "ade14" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "1049.092970521542"^^xsd:double ;
        gpml:y            "787.1560360071906"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id9673afb8/Point/ee3a4787fb41c028923469f78cae30fe>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4331_r135060> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id9673afb8> ;
        gpml:graphRef     "f47e2" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "1326.168831168831"^^xsd:double ;
        gpml:y            "541.5606060606054"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Group/c5e28>
        rdf:type          gpml:Group ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4331_r135060> ;
        gpml:graphId      "c5e28" ;
        gpml:groupId      "b9176" ;
        gpml:style        "Group" .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/DataNode/cf873>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4331_r135060> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Group/f47e2> ;
        gpml:align           "Center" ;
        gpml:centerX         "1371.1688311688313"^^xsd:double ;
        gpml:centerY         "591.0606060606054"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "cf873" ;
        gpml:groupRef        "b91c5" ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "RELB" ;
        gpml:type            "Protein" ;
        gpml:valign          "Middle" ;
        gpml:width           "90.0"^^xsd:double ;
        gpml:xrefDataSource  "UniProtKB" ;
        gpml:xrefId          "Q01201" ;
        gpml:zorder          "32848"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/idc5a379ce>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4331_r135060> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "idc5a379ce" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/idc5a379ce/Point/e3632abba3c3601356cd0eadf5dd4256> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/idc5a379ce/Point/25311b0161f70c572597424120ec6a8b> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/DataNode/cecc1>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4331_r135060> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Group/c0c97> ;
        gpml:align           "Center" ;
        gpml:centerX         "1169.0607909551406"^^xsd:double ;
        gpml:centerY         "242.37926399818784"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "14.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "cecc1" ;
        gpml:groupRef        "a08cd" ;
        gpml:hasComment      <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Comment/ef7ecff409e9d8c6f70835ed2854daa9> ;
        gpml:height          "28.919703884103914"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "ERK1" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "61.843845920311935"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000102882" ;
        gpml:zorder          "32837"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/idf1cd16b7/Point/bf59eecfe5956b2eda2b525cb8a05617>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4331_r135060> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/idf1cd16b7> ;
        gpml:graphRef     "a26ea" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "1294.944598630645"^^xsd:double ;
        gpml:y            "734.8688484982284"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/DataNode/b77db>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Group/e3505> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060> ;
        gpml:align           "Center" ;
        gpml:centerX         "992.0511887073062"^^xsd:double ;
        gpml:centerY         "730.860429607732"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "14.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "b77db" ;
        gpml:groupRef        "eda44" ;
        gpml:hasComment      <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Comment/5d411785637ac8345a86bfd38c290783> ;
        gpml:height          "34.475824915861324"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "VEGF" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "80.07553177703033"^^xsd:double ;
        gpml:xrefDataSource  "" ;
        gpml:xrefId          "" ;
        gpml:zorder          "32852"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/ide74fcb2f/Point/3644f8949ba9165f4400c5cb474c7811>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4331_r135060> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/ide74fcb2f> ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "1010.0"^^xsd:double ;
        gpml:y            "859.3853514654717"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/idc30364ec/Point/5297978759bbe30b2b9df7a0030a0524>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4331_r135060> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/idc30364ec> ;
        gpml:graphRef     "c5e28" ;
        gpml:relX         "1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "1412.732510288066"^^xsd:double ;
        gpml:y            "871.3034288830804"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id29a142bb/Point/b42d27560b00d4e16d80821ccda2e6d2>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4331_r135060> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id29a142bb> ;
        gpml:graphRef     "f52c7" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "-0.5"^^xsd:double ;
        gpml:x            "555.4665707257683"^^xsd:double ;
        gpml:y            "745.4771053127852"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/DataNode/b037b>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4331_r135060> ;
        gpml:align           "Center" ;
        gpml:centerX         "1372.3486916690995"^^xsd:double ;
        gpml:centerY         "391.4944645068202"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "b037b" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "RoundedRectangle" ;
        gpml:textlabel       "Migration" ;
        gpml:type            "Pathway" ;
        gpml:valign          "Middle" ;
        gpml:width           "165.0119047619046"^^xsd:double ;
        gpml:xrefDataSource  "" ;
        gpml:xrefId          "" ;
        gpml:zorder          "32777"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id986704b1>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4331_r135060> ;
        gpml:color          "0" ;
        gpml:connectorType  "Elbow" ;
        gpml:graphId        "id986704b1" ;
        gpml:hasAnchor      <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id986704b1/Anchor/b4aa7> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id986704b1/Anchor/ed960> ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id986704b1/Point/1576d1f318855f6ca355031982675d9d> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id986704b1/Point/c98adf45c138a865ee2126237726ec11> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/DataNode/b97b1>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4331_r135060> ;
        gpml:align           "Center" ;
        gpml:centerX         "1201.4406414082277"^^xsd:double ;
        gpml:centerY         "126.11983949298374"^^xsd:double ;
        gpml:color           "14961e" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "14.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Bold" ;
        gpml:graphId         "b97b1" ;
        gpml:height          "38.5"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "RoundedRectangle" ;
        gpml:textlabel       "VEGF signaling" ;
        gpml:type            "Pathway" ;
        gpml:valign          "Middle" ;
        gpml:width           "174.1252017046388"^^xsd:double ;
        gpml:xrefDataSource  "WikiPathways" ;
        gpml:xrefId          "WP1919" ;
        gpml:zorder          "32789"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id959f9a3b/Point/5999a36205813a6f52935867a22375a4>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4331_r135060> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id959f9a3b> ;
        gpml:graphRef     "fbb94" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "707.2962694530447"^^xsd:double ;
        gpml:y            "454.86761792540455"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id959f9a3b/Point/a1b9962d2ab7d3115240a41a93e44eee>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4331_r135060> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id959f9a3b> ;
        gpml:graphRef     "cd539" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "707.2962694530447"^^xsd:double ;
        gpml:y            "513.9866655444507"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id9673afb8/Point/82353ab490b96b17ee850f378acca0a1>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4331_r135060> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id9673afb8> ;
        gpml:graphRef     "c532b" ;
        gpml:relX         "-0.5"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "1351.751606598269"^^xsd:double ;
        gpml:y            "525.520486050501"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/DataNode/f98f0>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4331_r135060> ;
        gpml:align           "Center" ;
        gpml:centerX         "1179.1225661092722"^^xsd:double ;
        gpml:centerY         "483.1266290884488"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "14.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "f98f0" ;
        gpml:height          "38.5"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "Integrins" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "107.04572940287215"^^xsd:double ;
        gpml:xrefDataSource  "" ;
        gpml:xrefId          "" ;
        gpml:zorder          "32781"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/idb2b8fbcb>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4331_r135060> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "idb2b8fbcb" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/idb2b8fbcb/Point/51e8d45e729750a54d0c832a181c27d1> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/idb2b8fbcb/Point/c4d2ad759ecf56da6b37ee1eea21afee> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/DataNode/ff221>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4331_r135060> ;
        gpml:align           "Center" ;
        gpml:centerX         "1007.2962694530463"^^xsd:double ;
        gpml:centerY         "435.61761792540455"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "14.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "ff221" ;
        gpml:height          "38.5"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "NO" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "107.04572940287215"^^xsd:double ;
        gpml:xrefDataSource  "" ;
        gpml:xrefId          "" ;
        gpml:zorder          "32782"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id385be037/Point/68f55b6083ca0326392b872b1405af94>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4331_r135060> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id385be037> ;
        gpml:graphRef     "dda79" ;
        gpml:relX         "-0.5"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "1176.6935210972795"^^xsd:double ;
        gpml:y            "905.5161710004108"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id629ea143>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4331_r135060> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "id629ea143" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id629ea143/Point/dffaf95d6d30f8732a052d2c0e548d25> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id629ea143/Point/f596ddbca609bd72774029fbf718a5d> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id986704b1/Point/c98adf45c138a865ee2126237726ec11>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4331_r135060> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id986704b1> ;
        gpml:graphRef     "d564b" ;
        gpml:relX         "1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "1205.951656440971"^^xsd:double ;
        gpml:y            "802.5524809489692"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id19d91719/Point/e93c6510633a9fecde87080ef20ec4c2>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4331_r135060> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id19d91719> ;
        gpml:graphRef     "cd612" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "399.7754776681596"^^xsd:double ;
        gpml:y            "241.8034774475904"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id2cbc362/Point/e152776e0b695612e17e4d3970394af8>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4331_r135060> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id2cbc362> ;
        gpml:graphRef     "af3e8" ;
        gpml:relX         "-0.5"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "417.8812568748124"^^xsd:double ;
        gpml:y            "668.7610859971157"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id4584ff82/Point/7152a79482257e21237e8d61557e9b30>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4331_r135060> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id4584ff82> ;
        gpml:graphRef     "c0c97" ;
        gpml:relX         "1.0"^^xsd:double ;
        gpml:relY         "0.5"^^xsd:double ;
        gpml:x            "1208.8470181503872"^^xsd:double ;
        gpml:y            "383.7478574476817"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id8dd1a750/Point/9032752900f9db0f4a74383fa542374e>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4331_r135060> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id8dd1a750> ;
        gpml:graphRef     "f98f0" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "1179.1225661092722"^^xsd:double ;
        gpml:y            "463.8766290884488"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/DataNode/af540>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4331_r135060> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Group/fbd22> ;
        gpml:align           "Center" ;
        gpml:centerX         "1152.428791739535"^^xsd:double ;
        gpml:centerY         "782.5524809489692"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "14.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "af540" ;
        gpml:groupRef        "a563a" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "TGFB1" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "107.04572940287215"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000105329" ;
        gpml:zorder          "32818"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id1d0ddcea/Point/4d9a6f5daea78e32ec265e9a3dcae7a8>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4331_r135060> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id1d0ddcea> ;
        gpml:graphRef     "b7ea0" ;
        gpml:relX         "-0.5"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "910.3409364127974"^^xsd:double ;
        gpml:y            "169.6841295640733"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Comment/ff42f29512bd4af9d9981263d4ffb90d>
        rdf:type          gpml:Comment ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4331_r135060/DataNode/f6230> ;
        gpml:commentText  "\"Platelet-derived growth factor is a dimeric glycoprotein that can be composed of two A subunits (PDGF-AA), two B subunits (PDGF-BB), or one of each (PDGF-AB).\" SOucre: [https://en.wikipedia.org/wiki/Platelet-derived_growth_factor]. Annotated with enzyme family identifier." .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/idf1cd16b7>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4331_r135060> ;
        gpml:color          "0" ;
        gpml:connectorType  "Elbow" ;
        gpml:graphId        "idf1cd16b7" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/idf1cd16b7/Point/bf59eecfe5956b2eda2b525cb8a05617> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/idf1cd16b7/Point/a9ae11b97d40ed5e22759c23f4edcfab> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id5ec3e853>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4331_r135060> ;
        gpml:color          "0" ;
        gpml:connectorType  "Elbow" ;
        gpml:graphId        "id5ec3e853" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id5ec3e853/Point/17ece6d7131461bf9a8c714950f48eed> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id5ec3e853/Point/7fa56b6715d26a66efc5044d86a3d659> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/iddc821bad>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4331_r135060> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "iddc821bad" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/iddc821bad/Point/153b46cf919ab9f627c0e042cefb44dc> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/iddc821bad/Point/f2f2bb41b7931e514f432fde09f78ae4> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Group/dadba>
        rdf:type          gpml:Group ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4331_r135060> ;
        gpml:graphId      "dadba" ;
        gpml:groupId      "cc039" ;
        gpml:style        "Complex" .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/DataNode/aceec>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4331_r135060> ;
        gpml:align           "Center" ;
        gpml:centerX         "242.82301251999286"^^xsd:double ;
        gpml:centerY         "302.3360714122004"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "14.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "aceec" ;
        gpml:height          "38.5"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "NOTCH3" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "107.04572940287215"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000074181" ;
        gpml:zorder          "32797"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/idd027111d/Point/d48832eea947bb479e6158ed415db27b>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4331_r135060> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/idd027111d> ;
        gpml:graphRef     "d3f91" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "802.8210237992296"^^xsd:double ;
        gpml:y            "435.61761792540455"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/idda7ad113/Point/b931b1f07f47c508ff4dacff8b02b0d3>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4331_r135060> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/idda7ad113> ;
        gpml:graphRef     "b4aa7" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "1568.225486831608"^^xsd:double ;
        gpml:y            "778.9285714285713"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id29a142bb/Point/d8d80f5acbf11e6a8ea6d2dbf4a4ee2c>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4331_r135060> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id29a142bb> ;
        gpml:graphRef     "af3e8" ;
        gpml:relX         "0.5"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "500.3872092557647"^^xsd:double ;
        gpml:y            "688.7610859971157"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/idd52875c3>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4331_r135060> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "idd52875c3" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/idd52875c3/Point/ca2202f07eac3e094634f504e027886d> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/idd52875c3/Point/968757e91fbdf8af9d64ef142ed2c59a> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id9620c5fe>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4331_r135060> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "id9620c5fe" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id9620c5fe/Point/a1ad7ebbf25b42c2f87ed84cc9c8b137> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id9620c5fe/Point/ac1ce30a3eae07dc2c991d3c7de4cda7> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/idf8af98a6>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4331_r135060> ;
        gpml:color          "0" ;
        gpml:connectorType  "Elbow" ;
        gpml:graphId        "idf8af98a6" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/idf8af98a6/Point/9f76dbf219d779ee6e963bc9dcea2d88> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/idf8af98a6/Point/4b012fe529871b137b78b4e829fefa60> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/idf8af98a6/Point/3cda09ec2e900c5e06617679ea2943df> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/ida82223d6>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4331_r135060> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "ida82223d6" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/ida82223d6/Point/3082bb6a0f2f1d76e6e9d998e8145537> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/ida82223d6/Point/d1146242e421b7baecf55d01ca833e59> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/ida53e28d3/Point/8e1b0c01474e701970ff37b332557481>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4331_r135060> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/ida53e28d3> ;
        gpml:graphRef     "b4783" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "1598.225486831608"^^xsd:double ;
        gpml:y            "822.4285714285713"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id6b9cef01/Point/875afaf7aedf8d283a8c38a1169570bd>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4331_r135060> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id6b9cef01> ;
        gpml:graphRef     "ae661" ;
        gpml:relX         "0.5"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "1046.0064782909237"^^xsd:double ;
        gpml:y            "241.8034774475904"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id629ea143/Point/f596ddbca609bd72774029fbf718a5d>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4331_r135060> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id629ea143> ;
        gpml:graphRef     "fbd22" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "1152.428791739535"^^xsd:double ;
        gpml:y            "760.5524809489692"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/idce9ec6d7/Point/33871990b37b475c6f81354bdf0d7767>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4331_r135060> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/idce9ec6d7> ;
        gpml:graphRef     "c0c97" ;
        gpml:relX         "1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "1208.8470181503872"^^xsd:double ;
        gpml:y            "329.13837565049977"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/DataNode/a4731>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4331_r135060> ;
        gpml:align           "Center" ;
        gpml:centerX         "522.8633693152899"^^xsd:double ;
        gpml:centerY         "53.89095107917156"^^xsd:double ;
        gpml:color           "14961e" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Bold" ;
        gpml:graphId         "a4731" ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "Sprouting angiogenesis" ;
        gpml:type            "Pathway" ;
        gpml:valign          "Middle" ;
        gpml:width           "174.12520170463887"^^xsd:double ;
        gpml:xrefDataSource  "" ;
        gpml:xrefId          "" ;
        gpml:zorder          "32796"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id57bda919>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4331_r135060> ;
        gpml:color          "0" ;
        gpml:connectorType  "Elbow" ;
        gpml:graphId        "id57bda919" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id57bda919/Point/8790f516c7a6e62ac582bf70899eec8a> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id57bda919/Point/8b94c069feb24a28d87ac9e05d356f15> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/idb158f72a>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4331_r135060> ;
        gpml:color          "0" ;
        gpml:connectorType  "Elbow" ;
        gpml:graphId        "idb158f72a" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/idb158f72a/Point/68921f8f615f1f42dfcb73ef5b75ce9e> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/idb158f72a/Point/c063d1e0ee100dd590fe3820a804fd60> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/DataNode/ed69e>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Group/c0c97> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060> ;
        gpml:align           "Center" ;
        gpml:centerX         "1169.0607909551404"^^xsd:double ;
        gpml:centerY         "300.2186717663959"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "14.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "ed69e" ;
        gpml:groupRef        "a08cd" ;
        gpml:height          "28.919703884103914"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "PI3K" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "61.843845920311935"^^xsd:double ;
        gpml:xrefDataSource  "InterPro" ;
        gpml:xrefId          "IPR000403" ;
        gpml:zorder          "32839"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Comment/e11aa637951c10ae0527c34d5a1464f2>
        rdf:type          gpml:Comment ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4331_r135060/DataNode/f2585> ;
        gpml:commentText  "aka ACVRL1" .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/idd027111d/Point/23550e233687febef3401dbb49304b7d>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4331_r135060> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/idd027111d> ;
        gpml:graphRef     "fbb94" ;
        gpml:relX         "1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "760.8191341544807"^^xsd:double ;
        gpml:y            "435.61761792540455"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/DataNode/b1d24>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4331_r135060> ;
        gpml:align           "Center" ;
        gpml:centerX         "88.48327015288453"^^xsd:double ;
        gpml:centerY         "221.52691312802096"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "14.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "b1d24" ;
        gpml:height          "38.5"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "SDF-1" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "107.04572940287215"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000107562" ;
        gpml:zorder          "32799"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/DataNode/da441>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4331_r135060> ;
        gpml:align           "Center" ;
        gpml:centerX         "541.2062850587856"^^xsd:double ;
        gpml:centerY         "222.5534774475904"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "14.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "da441" ;
        gpml:height          "38.5"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "DLL4" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "107.04572940287215"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000128917" ;
        gpml:zorder          "32791"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/DataNode/b646b>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4331_r135060> ;
        gpml:align           "Center" ;
        gpml:centerX         "866.1359504501603"^^xsd:double ;
        gpml:centerY         "222.5534774475904"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "14.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "b646b" ;
        gpml:hasComment      <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Comment/ac6b019953454e81178ce3b179f673ba> ;
        gpml:height          "38.5"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "VEGFR3" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "107.04572940287215"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000037280" ;
        gpml:zorder          "32769"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id1d0ddcea>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4331_r135060> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "id1d0ddcea" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id1d0ddcea/Point/4d9a6f5daea78e32ec265e9a3dcae7a8> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id1d0ddcea/Point/393822f214e75c940a2a7e283a764efa> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/DataNode/e7903>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4331_r135060> ;
        gpml:align           "Center" ;
        gpml:centerX         "942.1661539147642"^^xsd:double ;
        gpml:centerY         "324.77052257933"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "14.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "e7903" ;
        gpml:height          "38.5"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "DLL2" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "107.04572940287215"^^xsd:double ;
        gpml:xrefDataSource  "" ;
        gpml:xrefId          "" ;
        gpml:zorder          "32772"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id7a8a4023/Point/593f1b15fd4b1d1801979be75fef2a46>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4331_r135060> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id7a8a4023> ;
        gpml:graphRef     "f52c7" ;
        gpml:relX         "1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "720.4784754876729"^^xsd:double ;
        gpml:y            "758.4338631699995"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id53776055>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4331_r135060> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "id53776055" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id53776055/Point/90add8addc6a74b02c177171977fb09f> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id53776055/Point/fce0343460a8f27d9aa7232526b25d2e> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/DataNode/c29d6>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4331_r135060> ;
        gpml:align           "Center" ;
        gpml:centerX         "523.2445758825609"^^xsd:double ;
        gpml:centerY         "20.656861173708776"^^xsd:double ;
        gpml:color           "14961e" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "14.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Bold" ;
        gpml:graphId         "c29d6" ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "RoundedRectangle" ;
        gpml:textlabel       "Notch signaling" ;
        gpml:type            "Pathway" ;
        gpml:valign          "Middle" ;
        gpml:width           "174.1252017046388"^^xsd:double ;
        gpml:xrefDataSource  "WikiPathways" ;
        gpml:xrefId          "WP268" ;
        gpml:zorder          "32790"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/DataNode/ea1df>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Group/dadba> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060> ;
        gpml:align           "Center" ;
        gpml:centerX         "559.7182239837099"^^xsd:double ;
        gpml:centerY         "931.6146669237528"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "14.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "ea1df" ;
        gpml:groupRef        "cc039" ;
        gpml:hasComment      <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Comment/f8f1346ae80fb9cd164288add566ae78> ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "ALK5\n" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "107.04572940287225"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000106799" ;
        gpml:zorder          "32825"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id866451/Point/5edc9308e651a83869d6b052b2255a0a>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4331_r135060> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id866451> ;
        gpml:graphRef     "cf120" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "1284.6046440500518"^^xsd:double ;
        gpml:y            "351.0182740306294"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/DataNode/b8df0>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4331_r135060> ;
        gpml:align           "Center" ;
        gpml:centerX         "1178.8534659249976"^^xsd:double ;
        gpml:centerY         "667.3420924777898"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "14.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "b8df0" ;
        gpml:height          "39.39881183437494"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "HIF1A" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "107.04572940287215"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000100644" ;
        gpml:zorder          "32812"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/DataNode/f2585>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4331_r135060> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Group/dadba> ;
        gpml:align           "Center" ;
        gpml:centerX         "559.7182239837099"^^xsd:double ;
        gpml:centerY         "911.6146669237528"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "14.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "f2585" ;
        gpml:groupRef        "cc039" ;
        gpml:hasComment      <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Comment/e11aa637951c10ae0527c34d5a1464f2> ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "ALK1\n" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "107.04572940287225"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000139567" ;
        gpml:zorder          "32824"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id92f6fdf>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4331_r135060> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "id92f6fdf" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id92f6fdf/Point/286bdf29084ea006b9ff877bbbe856f3> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id92f6fdf/Point/69af5a964a34b796364d4121fc80151e> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id29a142bb>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4331_r135060> ;
        gpml:color          "0" ;
        gpml:connectorType  "Elbow" ;
        gpml:graphId        "id29a142bb" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id29a142bb/Point/b42d27560b00d4e16d80821ccda2e6d2> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id29a142bb/Point/d8d80f5acbf11e6a8ea6d2dbf4a4ee2c> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "32817"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id8dd1a750>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4331_r135060> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "id8dd1a750" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id8dd1a750/Point/eb616685ae4f57f716983ab20e47477d> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id8dd1a750/Point/9032752900f9db0f4a74383fa542374e> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "32832"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/DataNode/bfe32>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Group/dc392> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060> ;
        gpml:align           "Center" ;
        gpml:centerX         "693.9596981814783"^^xsd:double ;
        gpml:centerY         "217.362202279805"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "14.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "bfe32" ;
        gpml:groupRef        "c3296" ;
        gpml:height          "38.5"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "Notch1" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "107.04572940287215"^^xsd:double ;
        gpml:xrefDataSource  "UniProtKB" ;
        gpml:xrefId          "P46531" ;
        gpml:zorder          "32768"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/DataNode/c80a0>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4331_r135060> ;
        gpml:align           "Center" ;
        gpml:centerX         "1375.2058345262426"^^xsd:double ;
        gpml:centerY         "309.5897026020577"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "c80a0" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "RoundedRectangle" ;
        gpml:textlabel       "Proliferation" ;
        gpml:type            "Pathway" ;
        gpml:valign          "Middle" ;
        gpml:width           "165.0119047619046"^^xsd:double ;
        gpml:xrefDataSource  "" ;
        gpml:xrefId          "" ;
        gpml:zorder          "32775"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/idda7ad113/Point/54aa78206794b3bcbcb7c8e052acf1b0>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4331_r135060> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/idda7ad113> ;
        gpml:graphRef     "af540" ;
        gpml:relX         "1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "1205.951656440971"^^xsd:double ;
        gpml:y            "782.5524809489692"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id385be037/Point/c20641eda94c56ed6243dfc7ba6db7ff>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4331_r135060> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id385be037> ;
        gpml:graphRef     "fbd22" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "1152.428791739535"^^xsd:double ;
        gpml:y            "844.5524809489692"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/idb2b8fbcb/Point/51e8d45e729750a54d0c832a181c27d1>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4331_r135060> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/idb2b8fbcb> ;
        gpml:graphRef     "a8fda" ;
        gpml:relX         "-0.5"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "244.93738386202557"^^xsd:double ;
        gpml:y            "477.70547390947104"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/DataNode/f8aa0>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4331_r135060> ;
        gpml:align           "Center" ;
        gpml:centerX         "1168.563643770941"^^xsd:double ;
        gpml:centerY         "172.42383181232694"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "14.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "f8aa0" ;
        gpml:height          "38.5"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "EPHB4" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "107.04572940287215"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000196411" ;
        gpml:zorder          "32774"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id9e26d8d8/Point/487672593da285da8e7ebc805fa58377>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4331_r135060> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id9e26d8d8> ;
        gpml:graphRef     "c70cc" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "815.6781666563722"^^xsd:double ;
        gpml:y            "533.2366655444507"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id3a82d99>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4331_r135060> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "id3a82d99" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id3a82d99/Point/5f24139ac797977fa701c963bb38cd71> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id3a82d99/Point/2e5cd9a7156e1e6a79a03f17e9b7142d> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "32827"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id82cb5971>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4331_r135060> ;
        gpml:color          "0" ;
        gpml:connectorType  "Elbow" ;
        gpml:graphId        "id82cb5971" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id82cb5971/Point/ca18f2d1a545f5c18bf17fbd4c012009> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id82cb5971/Point/2065203a3334a73c2ebf6cf17e2dc3b4> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Group/f47e2>
        rdf:type          gpml:Group ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4331_r135060> ;
        gpml:graphId      "f47e2" ;
        gpml:groupId      "b91c5" ;
        gpml:style        "Complex" .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id9bf1f2c/Point/677c9a4c3961fd3969415c707128f892>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4331_r135060> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id9bf1f2c> ;
        gpml:graphRef     "f520a" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "69.87222809317751"^^xsd:double ;
        gpml:y            "473.11939890947156"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/DataNode/d564b>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4331_r135060> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Group/fbd22> ;
        gpml:align           "Center" ;
        gpml:centerX         "1152.428791739535"^^xsd:double ;
        gpml:centerY         "802.5524809489692"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "14.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "d564b" ;
        gpml:groupRef        "a563a" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "TGFB2" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "107.04572940287225"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000092969" ;
        gpml:zorder          "32819"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id1ed5e8f9/Point/a60d92c93621e173b488516560d5e8eb>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4331_r135060> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id1ed5e8f9> ;
        gpml:graphRef     "f2585" ;
        gpml:relX         "0.5"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "586.479656334428"^^xsd:double ;
        gpml:y            "901.6146669237528"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/idf5a00189>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4331_r135060> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "idf5a00189" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/idf5a00189/Point/8aede580e571abbe2daeffe3b52bc571> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/idf5a00189/Point/f512247ccea238e9dde9cac0b131f28e> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id7c08421a/Point/aa96088af772e47dd775523e4a46249b>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4331_r135060> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id7c08421a> ;
        gpml:graphRef     "ae661" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "1019.2450459402057"^^xsd:double ;
        gpml:y            "241.8034774475904"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/DataNode/e0c26>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4331_r135060> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Group/c0c97> ;
        gpml:align           "Center" ;
        gpml:centerX         "1169.0607909551404"^^xsd:double ;
        gpml:centerY         "329.1383756504998"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "14.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "e0c26" ;
        gpml:groupRef        "a08cd" ;
        gpml:height          "28.919703884103914"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "AKT1" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "61.843845920311935"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000142208" ;
        gpml:zorder          "32840"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id19d91719/Point/2ff6cb254f4d58bfa646637b27304bf2>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4331_r135060> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id19d91719> ;
        gpml:graphRef     "dc392" ;
        gpml:relX         "-0.5"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "663.1982658307602"^^xsd:double ;
        gpml:y            "244.612202279805"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/DataNode/d7137>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4331_r135060> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Group/c5e28> ;
        gpml:align           "Center" ;
        gpml:centerX         "1364.9802034433103"^^xsd:double ;
        gpml:centerY         "859.2274312697614"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "14.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "d7137" ;
        gpml:groupRef        "b9176" ;
        gpml:height          "24.151995226638064"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "SMAD2" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "79.50461368951079"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000175387" ;
        gpml:zorder          "32822"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/DataNode/d1906>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4331_r135060> ;
        gpml:align           "Center" ;
        gpml:centerX         "342.7481717137473"^^xsd:double ;
        gpml:centerY         "606.7299946916647"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "d1906" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "RoundedRectangle" ;
        gpml:textlabel       "Vessel maturation" ;
        gpml:type            "Pathway" ;
        gpml:valign          "Middle" ;
        gpml:width           "165.0119047619046"^^xsd:double ;
        gpml:xrefDataSource  "" ;
        gpml:xrefId          "" ;
        gpml:zorder          "32807"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/DataNode/cdd2d>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4331_r135060> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Group/a26ea> ;
        gpml:align           "Center" ;
        gpml:centerX         "1339.2207867829115"^^xsd:double ;
        gpml:centerY         "734.8688484982284"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "14.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "cdd2d" ;
        gpml:groupRef        "b9b71" ;
        gpml:height          "24.8321531021484"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "SMAD5" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "72.55237630453252"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000113658" ;
        gpml:zorder          "32843"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/ide74fcb2f>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4331_r135060> ;
        gpml:color          "0" ;
        gpml:connectorType  "Elbow" ;
        gpml:graphId        "ide74fcb2f" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/ide74fcb2f/Point/47892db9c36e660fc38bd4f9bdb1a266> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/ide74fcb2f/Point/8ca3ff53bd86da17111fc88ef0ec3507> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/ide74fcb2f/Point/3644f8949ba9165f4400c5cb474c7811> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/idc30364ec/Point/5ceef0c2a21c2121de8aebd5da5dc62c>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4331_r135060> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/idc30364ec> ;
        gpml:graphRef     "c380d" ;
        gpml:relX         "0.5"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "1598.225486831608"^^xsd:double ;
        gpml:y            "389.68779312953916"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/idc92c6d04>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4331_r135060> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "idc92c6d04" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/idc92c6d04/Point/516873610703e3182bf645ec4b68a39e> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/idc92c6d04/Point/3d7ba9a912ae2f5630210ce51e069e04> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/DataNode/fbb94>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4331_r135060> ;
        gpml:align           "Center" ;
        gpml:centerX         "707.2962694530447"^^xsd:double ;
        gpml:centerY         "435.61761792540455"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "14.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "fbb94" ;
        gpml:hasComment      <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Comment/dfc0ca1e4f1a777747e6ccaabd894ca2> ;
        gpml:height          "38.5"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "mKitL" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "107.04572940287215"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000049130" ;
        gpml:zorder          "32784"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/idc30364ec>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4331_r135060> ;
        gpml:color          "0" ;
        gpml:connectorType  "Elbow" ;
        gpml:graphId        "idc30364ec" ;
        gpml:hasAnchor      <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/idc30364ec/Anchor/b4783> ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/idc30364ec/Point/5ceef0c2a21c2121de8aebd5da5dc62c> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/idc30364ec/Point/5297978759bbe30b2b9df7a0030a0524> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id5aa7f50c/Point/e050aeb4a24feb91129b2694366e6aee>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4331_r135060> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id5aa7f50c> ;
        gpml:graphRef     "dc392" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.5"^^xsd:double ;
        gpml:x            "632.4368334800422"^^xsd:double ;
        gpml:y            "221.362202279805"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id4584ff82/Point/d19a93ec7d3c4d913c73e2957db65807>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4331_r135060> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id4584ff82> ;
        gpml:graphRef     "d4a72" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "1318.2554377008453"^^xsd:double ;
        gpml:y            "436.18834205784003"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id3a82d99/Point/2e5cd9a7156e1e6a79a03f17e9b7142d>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4331_r135060> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id3a82d99> ;
        gpml:graphRef     "c80a0" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "1292.6998821452903"^^xsd:double ;
        gpml:y            "309.5897026020577"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id1ed5e8f9/Point/5679a96f2bb692a149b4fd94fb787360>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4331_r135060> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id1ed5e8f9> ;
        gpml:graphRef     "af19a" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "1049.092970521542"^^xsd:double ;
        gpml:y            "820.0580194701474"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/idd52875c3/Point/ca2202f07eac3e094634f504e027886d>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4331_r135060> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/idd52875c3> ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "1569.0"^^xsd:double ;
        gpml:y            "733.4285714285711"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/idad1e67e7/Anchor/af19a>
        rdf:type          gpml:Anchor ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4331_r135060> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/idad1e67e7> ;
        gpml:graphId      "af19a" ;
        gpml:position     "0.35117617309163757"^^xsd:double ;
        gpml:shape        "None" .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/idc2704644/Point/918f861f1c3347d20427d9a2c0367ccc>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4331_r135060> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/idc2704644> ;
        gpml:graphRef     "e7903" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "888.6432892133282"^^xsd:double ;
        gpml:y            "324.77052257933"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id9bf1f2c>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4331_r135060> ;
        gpml:color          "0" ;
        gpml:connectorType  "Elbow" ;
        gpml:graphId        "id9bf1f2c" ;
        gpml:hasAnchor      <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id9bf1f2c/Anchor/c1290> ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id9bf1f2c/Point/677c9a4c3961fd3969415c707128f892> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id9bf1f2c/Point/139a6ccd89e3d6af9499cf9817e29b6f> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/DataNode/e5c5a>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Group/f47e2> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060> ;
        gpml:align           "Center" ;
        gpml:centerX         "1371.1688311688313"^^xsd:double ;
        gpml:centerY         "566.0606060606054"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "e5c5a" ;
        gpml:groupRef        "b91c5" ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "RELA" ;
        gpml:type            "Protein" ;
        gpml:valign          "Middle" ;
        gpml:width           "90.0"^^xsd:double ;
        gpml:xrefDataSource  "UniProtKB" ;
        gpml:xrefId          "Q04206" ;
        gpml:zorder          "32847"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id986704b1/Anchor/b4aa7>
        rdf:type          gpml:Anchor ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4331_r135060> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id986704b1> ;
        gpml:graphId      "b4aa7" ;
        gpml:position     "0.4978435864626382"^^xsd:double ;
        gpml:shape        "None" .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/DataNode/d3f91>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4331_r135060> ;
        gpml:align           "Center" ;
        gpml:centerX         "856.3438885006657"^^xsd:double ;
        gpml:centerY         "435.61761792540455"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "14.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "d3f91" ;
        gpml:height          "38.5"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "MMP9" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "107.04572940287215"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000100985" ;
        gpml:zorder          "32783"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id82cb5971/Point/2065203a3334a73c2ebf6cf17e2dc3b4>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4331_r135060> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id82cb5971> ;
        gpml:graphRef     "e3505" ;
        gpml:relX         "1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "1040.0889545958216"^^xsd:double ;
        gpml:y            "696.3846046918707"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id5ec3e853/Point/17ece6d7131461bf9a8c714950f48eed>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4331_r135060> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id5ec3e853> ;
        gpml:graphRef     "dadba" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "494.1953592822738"^^xsd:double ;
        gpml:y            "921.6146669237528"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id986704b1/Anchor/ed960>
        rdf:type          gpml:Anchor ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4331_r135060> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id986704b1> ;
        gpml:graphId      "ed960" ;
        gpml:position     "0.575643613854522"^^xsd:double ;
        gpml:shape        "None" .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id454a05b4/Point/a52ba3edd4b491bd12bd7663d00580ae>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4331_r135060> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id454a05b4> ;
        gpml:graphRef     "c0c97" ;
        gpml:relX         "1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "1208.8470181503872"^^xsd:double ;
        gpml:y            "329.13837565049977"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/idf8af98a6/Point/4b012fe529871b137b78b4e829fefa60>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4331_r135060> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/idf8af98a6> ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "600.3355704697987"^^xsd:double ;
        gpml:y            "570.0430088214439"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Comment/ac6b019953454e81178ce3b179f673ba>
        rdf:type          gpml:Comment ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4331_r135060/DataNode/b646b> ;
        gpml:commentText  "aka FLT4" .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id6e32ab22>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4331_r135060> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "id6e32ab22" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id6e32ab22/Point/bfe91c862409a7b72b81fa17c23450cb> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id6e32ab22/Point/35832b00dbcac11cf6435c6bf20d79d5> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id6e32ab22/Point/35832b00dbcac11cf6435c6bf20d79d5>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4331_r135060> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id6e32ab22> ;
        gpml:graphRef     "cda4d" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "277.39343827624714"^^xsd:double ;
        gpml:y            "531.4091240666655"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/DataNode/e6c37>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Group/c0c97> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060> ;
        gpml:align           "Center" ;
        gpml:centerX         "1169.0607909551402"^^xsd:double ;
        gpml:centerY         "358.05807953460373"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "14.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "e6c37" ;
        gpml:groupRef        "a08cd" ;
        gpml:hasComment      <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Comment/e8cb58b351c43e3e593c306d5cab2260> ;
        gpml:height          "28.919703884103914"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "JNK1" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "61.843845920311935"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000107643" ;
        gpml:zorder          "32842"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Group/f71c7>
        rdf:type          gpml:Group ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4331_r135060> ;
        gpml:graphId      "f71c7" ;
        gpml:groupId      "d4da1" ;
        gpml:style        "Group" .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/ide138953b/Point/ebf9ad7d6116a6a33d8fdfd3e7e36035>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4331_r135060> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/ide138953b> ;
        gpml:graphRef     "e2cab" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "169.81969059317777"^^xsd:double ;
        gpml:y            "418.69756765947267"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/idad1e67e7/Point/4bd66bd33160ac22770b448c2d19ec81>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4331_r135060> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/idad1e67e7> ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "1049.092970521542"^^xsd:double ;
        gpml:y            "802.5524809489692"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/DataNode/ce82e>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4331_r135060> ;
        gpml:align           "Center" ;
        gpml:centerX         "853.3350889905253"^^xsd:double ;
        gpml:centerY         "371.0441686734865"^^xsd:double ;
        gpml:color           "ff0000" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "ce82e" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "RoundedRectangle" ;
        gpml:textlabel       "Arteriolar specification" ;
        gpml:type            "Pathway" ;
        gpml:valign          "Middle" ;
        gpml:width           "165.0119047619046"^^xsd:double ;
        gpml:xrefDataSource  "" ;
        gpml:xrefId          "" ;
        gpml:zorder          "32788"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/DataNode/f4b2a>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4331_r135060> ;
        gpml:align           "Center" ;
        gpml:centerX         "88.48327015288459"^^xsd:double ;
        gpml:centerY         "302.3360714122004"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "14.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "f4b2a" ;
        gpml:height          "38.5"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "CXCR4" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "107.04572940287215"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000121966" ;
        gpml:zorder          "32798"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/DataNode/c380d>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4331_r135060> ;
        gpml:align           "Center" ;
        gpml:centerX         "1568.225486831608"^^xsd:double ;
        gpml:centerY         "379.68779312953916"^^xsd:double ;
        gpml:color           "14961e" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Bold" ;
        gpml:graphId         "c380d" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "RoundedRectangle" ;
        gpml:textlabel       "Angiogenesis" ;
        gpml:type            "Pathway" ;
        gpml:valign          "Middle" ;
        gpml:width           "120.0"^^xsd:double ;
        gpml:xrefDataSource  "WikiPathways" ;
        gpml:xrefId          "WP1993" ;
        gpml:zorder          "32780"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id9bf1f2c/Anchor/c1290>
        rdf:type          gpml:Anchor ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4331_r135060> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id9bf1f2c> ;
        gpml:graphId      "c1290" ;
        gpml:position     "0.834531445765707"^^xsd:double ;
        gpml:shape        "None" .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id986704b1/Point/1576d1f318855f6ca355031982675d9d>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4331_r135060> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id986704b1> ;
        gpml:graphRef     "c380d" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "1568.225486831608"^^xsd:double ;
        gpml:y            "389.68779312953916"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id385be037>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4331_r135060> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "id385be037" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id385be037/Point/c20641eda94c56ed6243dfc7ba6db7ff> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id385be037/Point/68f55b6083ca0326392b872b1405af94> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id7a8a4023/Point/339abd97ffef0478560cb119de42037a>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4331_r135060> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id7a8a4023> ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "932.0861678004535"^^xsd:double ;
        gpml:y            "780.4931720594843"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/idf5a00189/Point/f512247ccea238e9dde9cac0b131f28e>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4331_r135060> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/idf5a00189> ;
        gpml:graphRef     "b7ea0" ;
        gpml:relX         "0.5"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "963.8638011142334"^^xsd:double ;
        gpml:y            "169.6841295640733"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/idc5a379ce/Point/25311b0161f70c572597424120ec6a8b>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4331_r135060> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/idc5a379ce> ;
        gpml:graphRef     "b646b" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "866.1359504501603"^^xsd:double ;
        gpml:y            "241.8034774475904"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Shape/ae741>
        rdf:type             gpml:shape ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4331_r135060> ;
        gpml:align           "Center" ;
        gpml:centerX         "259.78060934317534"^^xsd:double ;
        gpml:centerY         "238.8405129787885"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "14.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "ae741" ;
        gpml:height          "55.62106581105604"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "3.0"^^xsd:double ;
        gpml:shape           "0.0"^^xsd:double ;
        gpml:shapeType       "Oval" ;
        gpml:textlabel       "SMC" ;
        gpml:valign          "Middle" ;
        gpml:width           "100.86970192460967"^^xsd:double ;
        gpml:zorder          "32801"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Group/dc392>
        rdf:type          gpml:Group ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4331_r135060> ;
        gpml:graphId      "dc392" ;
        gpml:groupId      "c3296" ;
        gpml:style        "Group" .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/idc2704644>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4331_r135060> ;
        gpml:color          "0" ;
        gpml:connectorType  "Elbow" ;
        gpml:graphId        "idc2704644" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/idc2704644/Point/b32473ce3a15e4b373abaf33051c2f17> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/idc2704644/Point/918f861f1c3347d20427d9a2c0367ccc> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Group/d4da8>
        rdf:type          gpml:Group ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4331_r135060> ;
        gpml:graphId      "d4da8" ;
        gpml:groupId      "ee410" ;
        gpml:style        "Group" .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/idc92c6d04/Point/516873610703e3182bf645ec4b68a39e>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4331_r135060> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/idc92c6d04> ;
        gpml:graphRef     "dc392" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "693.9596981814783"^^xsd:double ;
        gpml:y            "244.612202279805"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/idafb8eddc/Point/55240aee60476aaf6538905f5779061c>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4331_r135060> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/idafb8eddc> ;
        gpml:graphRef     "f4b2a" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "34.96040545144851"^^xsd:double ;
        gpml:y            "302.3360714122004"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/iddc821bad/Point/f2f2bb41b7931e514f432fde09f78ae4>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4331_r135060> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/iddc821bad> ;
        gpml:graphRef     "f4b2a" ;
        gpml:relX         "1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "142.00613485432066"^^xsd:double ;
        gpml:y            "302.3360714122004"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id26cb2b8e>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4331_r135060> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "id26cb2b8e" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id26cb2b8e/Point/4b829d51c096d627dd2fdcc2d4531bd0> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id26cb2b8e/Point/fbab06ea23cdb90ef8417f3650f4f041> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/idc2704644/Point/b32473ce3a15e4b373abaf33051c2f17>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4331_r135060> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/idc2704644> ;
        gpml:graphRef     "dc392" ;
        gpml:relX         "0.5"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "724.7211305321964"^^xsd:double ;
        gpml:y            "244.612202279805"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id53776055/Point/90add8addc6a74b02c177171977fb09f>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4331_r135060> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id53776055> ;
        gpml:graphRef     "dda79" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "1149.9320887465615"^^xsd:double ;
        gpml:y            "915.5161710004108"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/ide138953b/Point/ba25feaa2387d0f3494dfcae9eb6e61c>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4331_r135060> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/ide138953b> ;
        gpml:graphRef     "c1290" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "69.87222809317751"^^xsd:double ;
        gpml:y            "552.163611895397"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/DataNode/c532b>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4331_r135060> ;
        gpml:align           "Center" ;
        gpml:centerX         "1393.0045827887452"^^xsd:double ;
        gpml:centerY         "515.520486050501"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "c532b" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "RoundedRectangle" ;
        gpml:textlabel       "Shear stress" ;
        gpml:type            "Pathway" ;
        gpml:valign          "Middle" ;
        gpml:width           "165.0119047619046"^^xsd:double ;
        gpml:xrefDataSource  "" ;
        gpml:xrefId          "" ;
        gpml:zorder          "32813"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/DataNode/fbd26>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Group/f47e2> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060> ;
        gpml:align           "Center" ;
        gpml:centerX         "1371.1688311688313"^^xsd:double ;
        gpml:centerY         "616.0606060606054"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "fbd26" ;
        gpml:groupRef        "b91c5" ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "REL" ;
        gpml:type            "Protein" ;
        gpml:valign          "Middle" ;
        gpml:width           "90.0"^^xsd:double ;
        gpml:xrefDataSource  "UniProtKB" ;
        gpml:xrefId          "Q04864" ;
        gpml:zorder          "32849"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/DataNode/b08cd>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Group/fbd22> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060> ;
        gpml:align           "Center" ;
        gpml:centerX         "1152.428791739535"^^xsd:double ;
        gpml:centerY         "822.5524809489692"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "14.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "b08cd" ;
        gpml:groupRef        "a563a" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "TGFB3" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "107.04572940287225"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000119699" ;
        gpml:zorder          "32820"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id7a8a4023>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4331_r135060> ;
        gpml:color          "0" ;
        gpml:connectorType  "Elbow" ;
        gpml:graphId        "id7a8a4023" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id7a8a4023/Point/593f1b15fd4b1d1801979be75fef2a46> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id7a8a4023/Point/8a6518d8d1eb2d223097b13c79a0d189> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id7a8a4023/Point/339abd97ffef0478560cb119de42037a> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/idce9ec6d7>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4331_r135060> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "idce9ec6d7" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/idce9ec6d7/Point/33871990b37b475c6f81354bdf0d7767> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/idce9ec6d7/Point/5ec1b9e00c629230fd4baa06ee60134> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "32831"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/DataNode/c9c08>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Group/c5e28> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060> ;
        gpml:align           "Center" ;
        gpml:centerX         "1364.9802034433103"^^xsd:double ;
        gpml:centerY         "883.3794264963994"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "14.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "c9c08" ;
        gpml:groupRef        "b9176" ;
        gpml:height          "24.151995226638075"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "SMAD3" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "79.50461368951089"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000166949" ;
        gpml:zorder          "32845"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/idbb748e76/Point/195d805478fb4c5a2396ceb99b4fd51c>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4331_r135060> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/idbb748e76> ;
        gpml:graphRef     "b8df0" ;
        gpml:relX         "0.5"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "1205.6148982757156"^^xsd:double ;
        gpml:y            "647.6426865606022"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/idc30364ec/Anchor/b4783>
        rdf:type          gpml:Anchor ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4331_r135060> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/idc30364ec> ;
        gpml:graphId      "b4783" ;
        gpml:position     "0.3513188552476372"^^xsd:double ;
        gpml:shape        "None" .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/DataNode/cd612>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4331_r135060> ;
        gpml:align           "Center" ;
        gpml:centerX         "399.7754776681596"^^xsd:double ;
        gpml:centerY         "222.5534774475904"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "14.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "cd612" ;
        gpml:height          "38.5"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "JAG1" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "107.04572940287215"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000101384" ;
        gpml:zorder          "32792"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id3c21b6ab/Point/43039df2212c681e38f9824d33b2de66>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4331_r135060> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id3c21b6ab> ;
        gpml:graphRef     "b646b" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "812.6130857487242"^^xsd:double ;
        gpml:y            "222.5534774475904"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id7c8c8c56>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4331_r135060> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "id7c8c8c56" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id7c8c8c56/Point/499986f8c27b61f118c7c49a51c75dfe> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id7c8c8c56/Point/5400321cc0a77118071bc3d54f1dc570> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Comment/7d0ed90a041cae0c5a837bbea719a236>
        rdf:type          gpml:Comment ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4331_r135060/DataNode/d8476> ;
        gpml:commentText  "aka Mothers against decapentaplegic homolog 9 also known as SMAD9, SMAD8, and MADH6" .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/DataNode/ae661>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4331_r135060> ;
        gpml:align           "Center" ;
        gpml:centerX         "1019.2450459402057"^^xsd:double ;
        gpml:centerY         "222.5534774475904"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "14.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "ae661" ;
        gpml:hasComment      <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Comment/185b60cdc66fca4baae6734a78de327a> ;
        gpml:height          "38.5"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "VEGFR2" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "107.04572940287215"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000128052" ;
        gpml:zorder          "32770"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id4584ff82>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4331_r135060> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "id4584ff82" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id4584ff82/Point/d19a93ec7d3c4d913c73e2957db65807> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id4584ff82/Point/7152a79482257e21237e8d61557e9b30> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "32828"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id7c08421a>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4331_r135060> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "id7c08421a" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id7c08421a/Point/c9c2796182d59e58bae2d64a34df5188> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id7c08421a/Point/aa96088af772e47dd775523e4a46249b> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/DataNode/be3e1>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Group/dc392> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060> ;
        gpml:align           "Center" ;
        gpml:centerX         "693.9596981814783"^^xsd:double ;
        gpml:centerY         "178.86220227980502"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "14.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "be3e1" ;
        gpml:groupRef        "c3296" ;
        gpml:height          "38.5"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "Notch4" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "107.04572940287215"^^xsd:double ;
        gpml:xrefDataSource  "UniProtKB" ;
        gpml:xrefId          "Q99466" ;
        gpml:zorder          "32851"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/DataNode/a60f1>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Group/a26ea> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060> ;
        gpml:align           "Center" ;
        gpml:centerX         "1339.2207867829115"^^xsd:double ;
        gpml:centerY         "710.0366953960801"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "14.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "a60f1" ;
        gpml:groupRef        "b9b71" ;
        gpml:height          "24.832153102148396"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "SMAD1" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "72.55237630453247"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000170365" ;
        gpml:zorder          "32821"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/ide138953b>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4331_r135060> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "ide138953b" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/ide138953b/Point/ba25feaa2387d0f3494dfcae9eb6e61c> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/ide138953b/Point/ebf9ad7d6116a6a33d8fdfd3e7e36035> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/idcb411f85>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4331_r135060> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "idcb411f85" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/idcb411f85/Point/4e40f3e087731a2a2feb4ee9a032e2f1> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/idcb411f85/Point/97e28d59512080ae4890e7c7bef1c3eb> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "32833"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/DataNode/bc9ce>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Group/f47e2> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060> ;
        gpml:align           "Center" ;
        gpml:centerX         "1281.1688311688308"^^xsd:double ;
        gpml:centerY         "591.0606060606054"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "bc9ce" ;
        gpml:groupRef        "b91c5" ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "NFKB1" ;
        gpml:type            "Protein" ;
        gpml:valign          "Middle" ;
        gpml:width           "90.0"^^xsd:double ;
        gpml:xrefDataSource  "UniProtKB" ;
        gpml:xrefId          "P19838" ;
        gpml:zorder          "32768"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Comment/f1c13588a7afc4f03e36e2452efef6a8>
        rdf:type          gpml:Comment ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4331_r135060/DataNode/ce5f7> ;
        gpml:commentText  "AKA MAPL1" .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/idda7ad113>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4331_r135060> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "idda7ad113" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/idda7ad113/Point/b931b1f07f47c508ff4dacff8b02b0d3> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/idda7ad113/Point/54aa78206794b3bcbcb7c8e052acf1b0> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/idad1e67e7/Anchor/ade14>
        rdf:type          gpml:Anchor ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4331_r135060> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/idad1e67e7> ;
        gpml:graphId      "ade14" ;
        gpml:position     "0.6308933086661298"^^xsd:double ;
        gpml:shape        "None" .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id7f609209/Point/f93ed51351ee80ec16a3d974169d2f7a>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4331_r135060> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id7f609209> ;
        gpml:graphRef     "d3f91" ;
        gpml:relX         "1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "909.8667532021018"^^xsd:double ;
        gpml:y            "435.61761792540455"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id7c8c8c56/Point/5400321cc0a77118071bc3d54f1dc570>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4331_r135060> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id7c8c8c56> ;
        gpml:graphRef     "f98f0" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "1179.1225661092722"^^xsd:double ;
        gpml:y            "502.3766290884488"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/DataNode/b7ea0>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4331_r135060> ;
        gpml:align           "Center" ;
        gpml:centerX         "937.1023687635154"^^xsd:double ;
        gpml:centerY         "150.4341295640733"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "14.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "b7ea0" ;
        gpml:height          "38.5"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "VEGF" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "107.04572940287215"^^xsd:double ;
        gpml:xrefDataSource  "InterPro" ;
        gpml:xrefId          "IPR000072" ;
        gpml:zorder          "32771"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Label/c3c77>
        rdf:type             gpml:Label ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4331_r135060> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Group/f47e2> ;
        gpml:align           "Center" ;
        gpml:centerX         "1281.168831168831"^^xsd:double ;
        gpml:centerY         "566.0606060606054"^^xsd:double ;
        gpml:color           "404040" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "c3c77" ;
        gpml:groupRef        "b91c5" ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:href            "" ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "None" ;
        gpml:textlabel       "NF-kappaB" ;
        gpml:valign          "Middle" ;
        gpml:width           "90.0"^^xsd:double ;
        gpml:zorder          "28672"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/DataNode/b9a6b>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4331_r135060> ;
        gpml:align           "Center" ;
        gpml:centerX         "1315.3796318787931"^^xsd:double ;
        gpml:centerY         "968.3008304883506"^^xsd:double ;
        gpml:color           "14961e" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "14.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Bold" ;
        gpml:graphId         "b9a6b" ;
        gpml:height          "38.5"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "RoundedRectangle" ;
        gpml:textlabel       "TGF-beta signaling" ;
        gpml:type            "Pathway" ;
        gpml:valign          "Middle" ;
        gpml:width           "174.1252017046388"^^xsd:double ;
        gpml:xrefDataSource  "WikiPathways" ;
        gpml:xrefId          "WP366" ;
        gpml:zorder          "32826"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id2cbc362>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4331_r135060> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "id2cbc362" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id2cbc362/Point/e152776e0b695612e17e4d3970394af8> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id2cbc362/Point/4dee1c60801324531078738ca2b1f335> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Group/a26ea>
        rdf:type          gpml:Group ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4331_r135060> ;
        gpml:graphId      "a26ea" ;
        gpml:groupId      "b9b71" ;
        gpml:style        "Group" .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id56380431>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4331_r135060> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "id56380431" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id56380431/Point/fd0d9312a9d5e5bf203a70c04fd8e06e> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id56380431/Point/87821fc2bd403598cbfc22aedbf20429> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "32835"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Comment/f8f1346ae80fb9cd164288add566ae78>
        rdf:type          gpml:Comment ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4331_r135060/DataNode/ea1df> ;
        gpml:commentText  "aka TGFBR1" .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id53776055/Point/fce0343460a8f27d9aa7232526b25d2e>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4331_r135060> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id53776055> ;
        gpml:graphRef     "dadba" ;
        gpml:relX         "1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "625.241088685146"^^xsd:double ;
        gpml:y            "921.6146669237528"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/DataNode/dda79>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4331_r135060> ;
        gpml:align           "Center" ;
        gpml:centerX         "1203.4549534479977"^^xsd:double ;
        gpml:centerY         "915.5161710004108"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "14.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "dda79" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "TGFBR1" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "107.04572940287225"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000106799" ;
        gpml:zorder          "32823"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/idad1e67e7>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4331_r135060> ;
        gpml:color          "0" ;
        gpml:connectorType  "Elbow" ;
        gpml:graphId        "idad1e67e7" ;
        gpml:hasAnchor      <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/idad1e67e7/Anchor/ade14> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/idad1e67e7/Anchor/af19a> ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/idad1e67e7/Point/4bd66bd33160ac22770b448c2d19ec81> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/idad1e67e7/Point/190547e0b310af737b339853ab3916cc> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/idad1e67e7/Point/3baa0a8cc055dcd9cb62a98a8885224a> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/DataNode/f52c7>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4331_r135060> ;
        gpml:align           "Center" ;
        gpml:centerX         "637.9725231067206"^^xsd:double ;
        gpml:centerY         "758.4338631699995"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "f52c7" ;
        gpml:height          "51.82703142885742"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "RoundedRectangle" ;
        gpml:textlabel       "Matrix and \ncollagen\ndeposition" ;
        gpml:type            "Pathway" ;
        gpml:valign          "Middle" ;
        gpml:width           "165.0119047619046"^^xsd:double ;
        gpml:xrefDataSource  "" ;
        gpml:xrefId          "" ;
        gpml:zorder          "32816"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Shape/e67a3>
        rdf:type             gpml:shape ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4331_r135060> ;
        gpml:align           "Center" ;
        gpml:centerX         "800.8589092662163"^^xsd:double ;
        gpml:centerY         "283.98925367976557"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "14.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "e67a3" ;
        gpml:height          "55.62106581105604"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "3.0"^^xsd:double ;
        gpml:shape           "0.0"^^xsd:double ;
        gpml:shapeType       "Oval" ;
        gpml:textlabel       "EC" ;
        gpml:valign          "Middle" ;
        gpml:width           "100.86970192460967"^^xsd:double ;
        gpml:zorder          "32793"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Shape/aadc6>
        rdf:type             gpml:shape ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4331_r135060> ;
        gpml:align           "Center" ;
        gpml:centerX         "462.87638135532075"^^xsd:double ;
        gpml:centerY         "107.4447465119967"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "14.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "aadc6" ;
        gpml:height          "55.62106581105604"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "3.0"^^xsd:double ;
        gpml:shape           "0.0"^^xsd:double ;
        gpml:shapeType       "Oval" ;
        gpml:textlabel       "Stalk EC" ;
        gpml:valign          "Middle" ;
        gpml:width           "100.86970192460967"^^xsd:double ;
        gpml:zorder          "32787"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/idafb8eddc/Point/c7154b6dffc0f2ea2c7d142691a09d90>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4331_r135060> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/idafb8eddc> ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "546.0"^^xsd:double ;
        gpml:y            "586.8197501476404"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id1ed5e8f9>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4331_r135060> ;
        gpml:color          "0" ;
        gpml:connectorType  "Elbow" ;
        gpml:graphId        "id1ed5e8f9" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id1ed5e8f9/Point/5679a96f2bb692a149b4fd94fb787360> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id1ed5e8f9/Point/a60d92c93621e173b488516560d5e8eb> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id57bda919/Point/8b94c069feb24a28d87ac9e05d356f15>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4331_r135060> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id57bda919> ;
        gpml:graphRef     "c0c97" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.5"^^xsd:double ;
        gpml:x            "1130.1388679949841"^^xsd:double ;
        gpml:y            "383.7478574476817"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/DataNode/b828f>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Group/e3505> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060> ;
        gpml:align           "Center" ;
        gpml:centerX         "992.0511887073062"^^xsd:double ;
        gpml:centerY         "696.3846046918707"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "14.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "b828f" ;
        gpml:groupRef        "eda44" ;
        gpml:height          "34.475824915861324"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "SDF-\n" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "80.07553177703033"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000107562" ;
        gpml:zorder          "32853"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id92f6fdf/Point/69af5a964a34b796364d4121fc80151e>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4331_r135060> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id92f6fdf> ;
        gpml:graphRef     "b1d24" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "88.48327015288453"^^xsd:double ;
        gpml:y            "240.77691312802096"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id1d0ddcea/Point/393822f214e75c940a2a7e283a764efa>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4331_r135060> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id1d0ddcea> ;
        gpml:graphRef     "b646b" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "866.1359504501603"^^xsd:double ;
        gpml:y            "203.3034774475904"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id8dd1a750/Point/eb616685ae4f57f716983ab20e47477d>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4331_r135060> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id8dd1a750> ;
        gpml:graphRef     "c0c97" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "1169.4929430726856"^^xsd:double ;
        gpml:y            "438.3573392448636"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id454a05b4/Point/d0a8cc16a4e0228ad8482e4828bc2ad0>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4331_r135060> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id454a05b4> ;
        gpml:graphRef     "c388a" ;
        gpml:relX         "-0.5"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "1294.4290488119568"^^xsd:double ;
        gpml:y            "260.0658930782482"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/idd027111d>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4331_r135060> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "idd027111d" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/idd027111d/Point/d48832eea947bb479e6158ed415db27b> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/idd027111d/Point/23550e233687febef3401dbb49304b7d> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id2cbc362/Point/4dee1c60801324531078738ca2b1f335>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4331_r135060> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id2cbc362> ;
        gpml:graphRef     "d1906" ;
        gpml:relX         "0.5"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "384.00114790422344"^^xsd:double ;
        gpml:y            "616.7299946916647"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/DataNode/c70cc>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4331_r135060> ;
        gpml:align           "Center" ;
        gpml:centerX         "869.2010313578082"^^xsd:double ;
        gpml:centerY         "533.2366655444507"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "14.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "c70cc" ;
        gpml:hasComment      <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Comment/6f2ed46e519bee5a955576562d10f427> ;
        gpml:height          "38.5"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "cKit" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "107.04572940287215"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000157404" ;
        gpml:zorder          "32786"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id9e26d8d8>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4331_r135060> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "id9e26d8d8" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id9e26d8d8/Point/b8b6a2bd1a38b234b5d95a49cb6c6182> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id9e26d8d8/Point/487672593da285da8e7ebc805fa58377> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id5aa7f50c>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4331_r135060> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "id5aa7f50c" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id5aa7f50c/Point/e050aeb4a24feb91129b2694366e6aee> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id5aa7f50c/Point/6833ea167c272e9411685b9f1affdf78> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Comment/e8cb58b351c43e3e593c306d5cab2260>
        rdf:type          gpml:Comment ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4331_r135060/DataNode/e6c37> ;
        gpml:commentText  "AKA MAPK8" .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/ide74fcb2f/Point/8ca3ff53bd86da17111fc88ef0ec3507>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4331_r135060> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/ide74fcb2f> ;
        gpml:graphRef     "ea1df" ;
        gpml:relX         "1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "613.241088685146"^^xsd:double ;
        gpml:y            "931.6146669237528"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/DataNode/b59f6>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4331_r135060> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Group/d4da8> ;
        gpml:align           "Center" ;
        gpml:centerX         "693.5853078118374"^^xsd:double ;
        gpml:centerY         "352.5086800605711"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "14.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "b59f6" ;
        gpml:groupRef        "ee410" ;
        gpml:height          "29.95490991136918"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "EPHB2" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "85.47048175486637"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000133216" ;
        gpml:zorder          "32836"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/idce9ec6d7/Point/5ec1b9e00c629230fd4baa06ee60134>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4331_r135060> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/idce9ec6d7> ;
        gpml:graphRef     "b037b" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "1289.8427392881472"^^xsd:double ;
        gpml:y            "391.4944645068202"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/idafb8eddc>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4331_r135060> ;
        gpml:color          "0" ;
        gpml:connectorType  "Elbow" ;
        gpml:graphId        "idafb8eddc" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/idafb8eddc/Point/656b4707c7f2f45c36b9df1abf26663b> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/idafb8eddc/Point/c7154b6dffc0f2ea2c7d142691a09d90> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/idafb8eddc/Point/55240aee60476aaf6538905f5779061c> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/ida53e28d3>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4331_r135060> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "ida53e28d3" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/ida53e28d3/Point/8e1b0c01474e701970ff37b332557481> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/ida53e28d3/Point/be665ddb9705bc52976a45d159113bf3> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/idf8af98a6/Point/9f76dbf219d779ee6e963bc9dcea2d88>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4331_r135060> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/idf8af98a6> ;
        gpml:graphRef     "cda4d" ;
        gpml:relX         "1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "359.89939065719943"^^xsd:double ;
        gpml:y            "521.4091240666655"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id7f609209>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4331_r135060> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "id7f609209" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id7f609209/Point/f93ed51351ee80ec16a3d974169d2f7a> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id7f609209/Point/b9f36a7e84235315951113464cbb3da2> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id9620c5fe/Point/a1ad7ebbf25b42c2f87ed84cc9c8b137>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4331_r135060> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id9620c5fe> ;
        gpml:graphRef     "f98f0" ;
        gpml:relX         "0.5"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "1205.8839984599902"^^xsd:double ;
        gpml:y            "463.8766290884488"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/ide828ebdd/Point/ac156fcf6d52b7a479347e1aefcd5581>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4331_r135060> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/ide828ebdd> ;
        gpml:graphRef     "aceec" ;
        gpml:relX         "1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "296.34587722142896"^^xsd:double ;
        gpml:y            "302.3360714122004"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/DataNode/d4a72>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4331_r135060> ;
        gpml:align           "Center" ;
        gpml:centerX         "1400.7613900817976"^^xsd:double ;
        gpml:centerY         "436.18834205784003"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "d4a72" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "RoundedRectangle" ;
        gpml:textlabel       "Apoptosis" ;
        gpml:type            "Pathway" ;
        gpml:valign          "Middle" ;
        gpml:width           "165.0119047619046"^^xsd:double ;
        gpml:xrefDataSource  "" ;
        gpml:xrefId          "" ;
        gpml:zorder          "32778"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id26cb2b8e/Point/4b829d51c096d627dd2fdcc2d4531bd0>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4331_r135060> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id26cb2b8e> ;
        gpml:graphRef     "f6230" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "253.6500925780441"^^xsd:double ;
        gpml:y            "674.3583379465571"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/ida82223d6/Point/d1146242e421b7baecf55d01ca833e59>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4331_r135060> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/ida82223d6> ;
        gpml:graphRef     "d4a72" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "1400.7613900817976"^^xsd:double ;
        gpml:y            "446.18834205784003"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/DataNode/af3e8>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4331_r135060> ;
        gpml:align           "Center" ;
        gpml:centerX         "459.1342330652885"^^xsd:double ;
        gpml:centerY         "678.7610859971157"^^xsd:double ;
        gpml:color           "ff0000" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Bold" ;
        gpml:graphId         "af3e8" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "RoundedRectangle" ;
        gpml:textlabel       "Remodeling arteriogenesis" ;
        gpml:type            "Pathway" ;
        gpml:valign          "Middle" ;
        gpml:width           "165.0119047619046"^^xsd:double ;
        gpml:xrefDataSource  "" ;
        gpml:xrefId          "" ;
        gpml:zorder          "32809"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/ida53e28d3/Point/be665ddb9705bc52976a45d159113bf3>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4331_r135060> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/ida53e28d3> ;
        gpml:graphRef     "b08cd" ;
        gpml:relX         "1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "1205.951656440971"^^xsd:double ;
        gpml:y            "822.5524809489692"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id7f8471d/Point/c1fcedeff16048c020bf6dddfa66d0e8>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4331_r135060> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id7f8471d> ;
        gpml:graphRef     "da441" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "541.2062850587856"^^xsd:double ;
        gpml:y            "203.3034774475904"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id7c8c8c56/Point/499986f8c27b61f118c7c49a51c75dfe>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4331_r135060> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id7c8c8c56> ;
        gpml:graphRef     "b8df0" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "1178.8534659249976"^^xsd:double ;
        gpml:y            "647.6426865606022"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4331_r135060/DataNode/be1dc>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4331_r135060> , <http://rdf.wikipathways.org/Pathway/WP4331_r135060/Group/c0c97> ;
        gpml:align           "Center" ;
        gpml:centerX         "1169.0607909551402"^^xsd:double ;
        gpml:centerY         "415.89748730281167"^^xsd:double ;
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<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/idcb411f85/Point/97e28d59512080ae4890e7c7bef1c3eb>
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<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id3a82d99/Point/5f24139ac797977fa701c963bb38cd71>
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<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id6b9cef01/Point/7328bd1e9f8709580077cc0bb175f88>
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<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id454a05b4>
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<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/idbb748e76/Point/7b11831d62d5e032b9ecb5cc1251805a>
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<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id5ec3e853/Point/7fa56b6715d26a66efc5044d86a3d659>
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<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Comment/185b60cdc66fca4baae6734a78de327a>
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<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/idd52875c3/Point/968757e91fbdf8af9d64ef142ed2c59a>
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<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/idb158f72a/Point/68921f8f615f1f42dfcb73ef5b75ce9e>
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<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id19d91719>
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<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id92f6fdf/Point/286bdf29084ea006b9ff877bbbe856f3>
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<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id9e26d8d8/Point/b8b6a2bd1a38b234b5d95a49cb6c6182>
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<http://rdf.wikipathways.org/Pathway/WP4331_r135060/DataNode/dd43d>
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<http://rdf.wikipathways.org/Pathway/WP4331_r135060/DataNode/ce5f7>
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<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/idcb411f85/Point/4e40f3e087731a2a2feb4ee9a032e2f1>
        rdf:type          gpml:Point ;
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<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/idb158f72a/Point/c063d1e0ee100dd590fe3820a804fd60>
        rdf:type          gpml:Point ;
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<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Group/e3505>
        rdf:type          gpml:Group ;
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<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id3c21b6ab>
        rdf:type            gpml:Interaction ;
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<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Shape/e2cab>
        rdf:type             gpml:shape ;
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        gpml:textlabel       "SMC" ;
        gpml:valign          "Middle" ;
        gpml:width           "100.86970192460967"^^xsd:double ;
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<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/iddc821bad/Point/153b46cf919ab9f627c0e042cefb44dc>
        rdf:type          gpml:Point ;
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<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id9bf1f2c/Point/139a6ccd89e3d6af9499cf9817e29b6f>
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<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/idf8af98a6/Point/3cda09ec2e900c5e06617679ea2943df>
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<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/idbb748e76>
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<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Comment/fa9a3cb82c9e18a9d1c7c6abfa9018d1>
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<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id6b9cef01>
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<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id3c21b6ab/Point/1797fdd1848738bed129019640e6ae74>
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<http://rdf.wikipathways.org/Pathway/WP4331_r135060/DataNode/bb5d9>
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<http://rdf.wikipathways.org/Pathway/WP4331_r135060/DataNode/f6230>
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<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/idb2b8fbcb/Point/c4d2ad759ecf56da6b37ee1eea21afee>
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<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/ide828ebdd/Point/a387153ecbb09e1e1be7cebb7e730bb5>
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<http://rdf.wikipathways.org/Pathway/WP4331_r135060/DataNode/cda4d>
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<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/idad1e67e7/Point/190547e0b310af737b339853ab3916cc>
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<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id56380431/Point/87821fc2bd403598cbfc22aedbf20429>
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<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/idafb8eddc/Point/656b4707c7f2f45c36b9df1abf26663b>
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<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Comment/dfc0ca1e4f1a777747e6ccaabd894ca2>
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<http://rdf.wikipathways.org/Pathway/WP4331_r135060/DataNode/d8476>
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<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id7a8a4023/Point/8a6518d8d1eb2d223097b13c79a0d189>
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<http://rdf.wikipathways.org/Pathway/WP4331_r135060/DataNode/dde4b>
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<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id866451>
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<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id7f609209/Point/b9f36a7e84235315951113464cbb3da2>
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<http://rdf.wikipathways.org/Pathway/WP4331_r135060/DataNode/fc102>
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<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Comment/5d411785637ac8345a86bfd38c290783>
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<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/id866451/Point/120b26b3a316b7e288c6f06858769414>
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<http://rdf.wikipathways.org/Pathway/WP4331_r135060/Interaction/idf1cd16b7/Point/a9ae11b97d40ed5e22759c23f4edcfab>
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