@prefix biopax:  <http://www.biopax.org/release/biopax-level3.owl#> .
@prefix cito:    <http://purl.org/spar/cito/> .
@prefix dc:      <http://purl.org/dc/elements/1.1/> .
@prefix dcterms: <http://purl.org/dc/terms/> .
@prefix foaf:    <http://xmlns.com/foaf/0.1/> .
@prefix freq:    <http://purl.org/cld/freq/> .
@prefix gpml:    <http://vocabularies.wikipathways.org/gpml#> .
@prefix obo:     <http://purl.obolibrary.org/obo/> .
@prefix owl:     <http://www.w3.org/2002/07/owl#> .
@prefix pav:     <http://purl.org/pav/> .
@prefix prov:    <http://www.w3.org/ns/prov#> .
@prefix rdf:     <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix rdfs:    <http://www.w3.org/2000/01/rdf-schema#> .
@prefix skos:    <http://www.w3.org/2004/02/skos/core#> .
@prefix void:    <http://rdfs.org/ns/void#> .
@prefix wp:      <http://vocabularies.wikipathways.org/wp#> .
@prefix wprdf:   <http://rdf.wikipathways.org/> .
@prefix xsd:     <http://www.w3.org/2001/XMLSchema#> .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/aa8a3>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:align           "Center" ;
        gpml:centerX         "982.8061759100196"^^xsd:double ;
        gpml:centerY         "728.4911080711361"^^xsd:double ;
        gpml:color           "ff" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "10.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "aa8a3" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "Ca²⁺" ;
        gpml:type            "Metabolite" ;
        gpml:valign          "Middle" ;
        gpml:width           "43.20793483927747"^^xsd:double ;
        gpml:xrefDataSource  "KEGG Compound" ;
        gpml:xrefId          "C00076" ;
        gpml:zorder          "32796"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Label/af14a>
        rdf:type             gpml:Label ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:align           "Center" ;
        gpml:centerX         "1079.79560808224"^^xsd:double ;
        gpml:centerY         "547.2377785879273"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "10.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "af14a" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:href            "" ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "None" ;
        gpml:textlabel       "Ubiquitin proteosome\ndysfunction" ;
        gpml:valign          "Middle" ;
        gpml:width           "101.45378151260456"^^xsd:double ;
        gpml:zorder          "32819"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id1d08513f/Point/e93c6510633a9fecde87080ef20ec4c2>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id1d08513f> ;
        gpml:graphRef     "f875f" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "1553.3493368014585"^^xsd:double ;
        gpml:y            "672.8320943002468"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Label/e9226>
        rdf:type             gpml:Label ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:align           "Center" ;
        gpml:centerX         "1090.6666666666667"^^xsd:double ;
        gpml:centerY         "1022.0"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "10.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "e9226" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:href            "" ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "None" ;
        gpml:textlabel       "Neurofilament damage" ;
        gpml:valign          "Middle" ;
        gpml:width           "125.33333333333357"^^xsd:double ;
        gpml:zorder          "28672"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/e9754/Point/8f3edb2532090844199fa0bf509e6ca7>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/e9754> ;
        gpml:graphRef     "faca6" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "351.89717802011444"^^xsd:double ;
        gpml:y            "728.357142857143"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id4993787b/Anchor/d6b95>
        rdf:type          gpml:Anchor ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id4993787b> ;
        gpml:graphId      "d6b95" ;
        gpml:position     "0.4"^^xsd:double ;
        gpml:shape        "None" .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/f3615>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:align           "Center" ;
        gpml:centerX         "1182.93789048144"^^xsd:double ;
        gpml:centerY         "706.7900622909483"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "10.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "f3615" ;
        gpml:height          "21.99999999999974"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "ASK1" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "63.99999999999989"^^xsd:double ;
        gpml:xrefDataSource  "Entrez Gene" ;
        gpml:xrefId          "4217" ;
        gpml:zorder          "32831"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id117c419f/Point/97b6d8f4be3056556197fb5410447e25>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id117c419f> ;
        gpml:graphRef     "e92a9" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "894.0"^^xsd:double ;
        gpml:y            "1077.0"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/c5456>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:align           "Center" ;
        gpml:centerX         "68.99999999999999"^^xsd:double ;
        gpml:centerY         "934.8731662335479"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "10.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "c5456" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "TNFalpha" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "62.00000000000009"^^xsd:double ;
        gpml:xrefDataSource  "Entrez Gene" ;
        gpml:xrefId          "7124" ;
        gpml:zorder          "32823"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id8d950ddc>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "id8d950ddc" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id8d950ddc/Point/c8bac20697a75afd636f353874987899> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id8d950ddc/Point/1a912f3fb4b8c26812a91b0ddbb1556b> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id69b8a250/Anchor/f433a>
        rdf:type          gpml:Anchor ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id69b8a250> ;
        gpml:graphId      "f433a" ;
        gpml:position     "0.4"^^xsd:double ;
        gpml:shape        "None" .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id1de00d7a/Point/53b07c85dfa2d58118444c5b51c8c0d3>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id1de00d7a> ;
        gpml:graphRef     "a22a5" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "964.0000000000005"^^xsd:double ;
        gpml:y            "871.5398329002153"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/e9754>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "e9754" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/e9754/Point/1f9fffef059f3f24ac74c01aeb9bbdd2> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/e9754/Point/8f3edb2532090844199fa0bf509e6ca7> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "32793"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/a5b33>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:color          "999999" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "a5b33" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/a5b33/Point/f16ec6e669d2f26e669a77b3bff76f5f> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/a5b33/Point/2dca465a47fb23b864ac72e66129db43> ;
        gpml:lineStyle      "Broken" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "32835"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id8abdb052/Point/d1146242e421b7baecf55d01ca833e59>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id8abdb052> ;
        gpml:graphRef     "a14b7" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "927.828537170263"^^xsd:double ;
        gpml:y            "1032.5398329002144"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idb6d19550>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:color          "0" ;
        gpml:connectorType  "Elbow" ;
        gpml:graphId        "idb6d19550" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idb6d19550/Point/9a0cbd85ba7a8a742203b240e4bd0ce2> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idb6d19550/Point/a9ae11b97d40ed5e22759c23f4edcfab> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idb6d19550/Point/bf59eecfe5956b2eda2b525cb8a05617> ;
        gpml:lineStyle      "Broken" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idd82ec964/Point/4e40f3e087731a2a2feb4ee9a032e2f1>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idd82ec964> ;
        gpml:graphRef     "de780" ;
        gpml:relX         "1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "479.59800664451825"^^xsd:double ;
        gpml:y            "184.74363233665557"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id8d950ddc/Point/c8bac20697a75afd636f353874987899>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id8d950ddc> ;
        gpml:graphRef     "d1b7a" ;
        gpml:relX         "1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "1232.0"^^xsd:double ;
        gpml:y            "1135.9999999999995"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id89599c68/Point/be665ddb9705bc52976a45d159113bf3>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id89599c68> ;
        gpml:graphRef     "b1e57" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "578.0"^^xsd:double ;
        gpml:y            "1123.0"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idd75808de/Point/9032752900f9db0f4a74383fa542374e>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idd75808de> ;
        gpml:graphRef     "f68e5" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "855.1999999999994"^^xsd:double ;
        gpml:y            "872.1398329002153"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/d3da2>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:align           "Center" ;
        gpml:centerX         "233.37748344370954"^^xsd:double ;
        gpml:centerY         "935.8731662335481"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "10.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "d3da2" ;
        gpml:height          "18.0000000000003"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "TNFalpha" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "64.00000000000003"^^xsd:double ;
        gpml:xrefDataSource  "Entrez Gene" ;
        gpml:xrefId          "7124" ;
        gpml:zorder          "32768"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/ida154c80d/Point/6d5110c71c1d478ae8c17a686605a3a6>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/ida154c80d> ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "736.8046875"^^xsd:double ;
        gpml:y            "982.0"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id9c0ea925>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "id9c0ea925" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id9c0ea925/Point/4b1eb853cb63ac2f8dcb5cd4cbae7a73> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id9c0ea925/Point/c36eb8716848fc441a93dd82b326bdc1> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Shape/bcc39>
        rdf:type             gpml:shape ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:align           "Center" ;
        gpml:centerX         "966.7345286951988"^^xsd:double ;
        gpml:centerY         "673.5891472868225"^^xsd:double ;
        gpml:color           "c0c0c0" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "10.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "bcc39" ;
        gpml:height          "246.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "3.0"^^xsd:double ;
        gpml:shape           "0.0"^^xsd:double ;
        gpml:shapeType       "Endoplasmic Reticulum" ;
        gpml:textlabel       "Endoplasmic reticulum (ER)" ;
        gpml:valign          "Middle" ;
        gpml:width           "472.7324929971992"^^xsd:double ;
        gpml:zorder          "16384"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idc2e2eee1/Point/b42d27560b00d4e16d80821ccda2e6d2>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idc2e2eee1> ;
        gpml:graphRef     "b06fe" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "1003.2377495462794"^^xsd:double ;
        gpml:y            "86.20309618803853"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/e0fcd>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:align           "Center" ;
        gpml:centerX         "827.4999999999998"^^xsd:double ;
        gpml:centerY         "982.366163432428"^^xsd:double ;
        gpml:color           "ff" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "10.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "e0fcd" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "ONOO-" ;
        gpml:type            "Metabolite" ;
        gpml:valign          "Middle" ;
        gpml:width           "45.0"^^xsd:double ;
        gpml:xrefDataSource  "HMDB" ;
        gpml:xrefId          "HMDB0002179" ;
        gpml:zorder          "32774"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idfa0808d1>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:color          "0" ;
        gpml:connectorType  "Elbow" ;
        gpml:graphId        "idfa0808d1" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idfa0808d1/Point/b7d647cb0653648e878572c4629797a0> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idfa0808d1/Point/b63eb8419fffb1fa34e821416f520dba> ;
        gpml:lineStyle      "Broken" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id7d4f73cd>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "id7d4f73cd" ;
        gpml:hasAnchor      <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id7d4f73cd/Anchor/afcbe> ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id7d4f73cd/Point/139a6ccd89e3d6af9499cf9817e29b6f> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id7d4f73cd/Point/35ac40a3f8313ccf59f560d8251d2268> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id69b8a250>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "id69b8a250" ;
        gpml:hasAnchor      <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id69b8a250/Anchor/f433a> ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id69b8a250/Point/c9c2796182d59e58bae2d64a34df5188> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id69b8a250/Point/aa96088af772e47dd775523e4a46249b> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id2bad9ea5/Point/fbab06ea23cdb90ef8417f3650f4f041>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id2bad9ea5> ;
        gpml:graphRef     "ffa60" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "981.3333333333333"^^xsd:double ;
        gpml:y            "1138.6666666666665"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/fefdb>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:align           "Center" ;
        gpml:centerX         "625.6657464725891"^^xsd:double ;
        gpml:centerY         "357.45736434108517"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "10.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "fefdb" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "SOD1" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "62.32374100719424"^^xsd:double ;
        gpml:xrefDataSource  "Entrez Gene" ;
        gpml:xrefId          "6647" ;
        gpml:zorder          "32812"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idd6d367a2/Point/5ec1b9e00c629230fd4baa06ee60134>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idd6d367a2> ;
        gpml:graphRef     "f4cf0" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "865.0"^^xsd:double ;
        gpml:y            "1116.5"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/State/d042e>
        rdf:type            gpml:State ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:color          "0" ;
        gpml:fillColor      "ffffff" ;
        gpml:graphId        "d042e" ;
        gpml:graphRef       "d1b7a" ;
        gpml:height         "15.0"^^xsd:double ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:relX           "-0.937984496124011"^^xsd:double ;
        gpml:relY           "-0.8449612403100673"^^xsd:double ;
        gpml:shapeType      "Triangle" ;
        gpml:stateOf        <http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/d1b7a> ;
        gpml:stateType      "Unknown" ;
        gpml:textlabel      "" ;
        gpml:width          "15.0"^^xsd:double ;
        gpml:zorder         "32769"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/f9f96/Point/a3e7d22053fc17c85aa7b2bc9ccbdfcd>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/f9f96> ;
        gpml:graphRef     "d820d" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "806.4817275747502"^^xsd:double ;
        gpml:y            "184.98338870431908"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id2dedab80>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "id2dedab80" ;
        gpml:hasAnchor      <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id2dedab80/Anchor/a56bc> ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id2dedab80/Point/68f55b6083ca0326392b872b1405af94> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id2dedab80/Point/c20641eda94c56ed6243dfc7ba6db7ff> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/a14b7>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:align           "Center" ;
        gpml:centerX         "927.828537170263"^^xsd:double ;
        gpml:centerY         "1022.5398329002144"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "10.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "a14b7" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "SOD1" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "62.32374100719424"^^xsd:double ;
        gpml:xrefDataSource  "Entrez Gene" ;
        gpml:xrefId          "6647" ;
        gpml:zorder          "32828"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id94a8676c/Point/ee8ca04ab66111fe203738b9c4b40a08>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id94a8676c> ;
        gpml:graphRef     "d3da2" ;
        gpml:relX         "1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "265.3774834437096"^^xsd:double ;
        gpml:y            "935.8731662335481"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/a1e19>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:align           "Center" ;
        gpml:centerX         "767.9845286951988"^^xsd:double ;
        gpml:centerY         "692.9263873647719"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "10.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "a1e19" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "Derlin-1" ;
        gpml:type            "Protein" ;
        gpml:valign          "Middle" ;
        gpml:width           "59.76750700280081"^^xsd:double ;
        gpml:xrefDataSource  "Entrez Gene" ;
        gpml:xrefId          "79139" ;
        gpml:zorder          "32797"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Label/dfe3d>
        rdf:type             gpml:Label ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:align           "Center" ;
        gpml:centerX         "1299.7093551316984"^^xsd:double ;
        gpml:centerY         "871.0263396911889"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "10.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "dfe3d" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:href            "" ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "DNA" ;
        gpml:valign          "Middle" ;
        gpml:width           "52.71571298819267"^^xsd:double ;
        gpml:zorder          "28672"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id7bbfe1e0>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "id7bbfe1e0" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id7bbfe1e0/Point/c98adf45c138a865ee2126237726ec11> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id7bbfe1e0/Point/1576d1f318855f6ca355031982675d9d> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/b69ab>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:align           "Center" ;
        gpml:centerX         "878.6666666666666"^^xsd:double ;
        gpml:centerY         "547.7692024990812"^^xsd:double ;
        gpml:color           "14961e" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Bold" ;
        gpml:graphId         "b69ab" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "RoundedRectangle" ;
        gpml:textlabel       "Proteasome" ;
        gpml:type            "Pathway" ;
        gpml:valign          "Middle" ;
        gpml:width           "80.0"^^xsd:double ;
        gpml:xrefDataSource  "WikiPathways" ;
        gpml:xrefId          "WP183" ;
        gpml:zorder          "32768"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idb3aea929>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "idb3aea929" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idb3aea929/Point/ba25feaa2387d0f3494dfcae9eb6e61c> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idb3aea929/Point/ebf9ad7d6116a6a33d8fdfd3e7e36035> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/bcc7f/Point/3c76226d8f5c65216944b93aafd7b741>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/bcc7f> ;
        gpml:graphRef     "b24b0" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "756.407530454042"^^xsd:double ;
        gpml:y            "1033.7436323366555"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id8eb40b49>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "id8eb40b49" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id8eb40b49/Point/230f48bd3bc54434fdd6ade86b9587a2> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id8eb40b49/Point/eeb1e2e4a33f742f4528a8868b2718d4> ;
        gpml:lineStyle      "Broken" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id19a072ea>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:color          "0" ;
        gpml:connectorType  "Elbow" ;
        gpml:graphId        "id19a072ea" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id19a072ea/Point/183efa6c796d14446c6c9253ccecbc70> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id19a072ea/Point/4b012fe529871b137b78b4e829fefa60> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id19a072ea/Point/d2c9dba13917a728aad556c931edb3cf> ;
        gpml:lineStyle      "Broken" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/ida1e5ab90/Point/5297978759bbe30b2b9df7a0030a0524>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/ida1e5ab90> ;
        gpml:graphRef     "f3615" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "1150.93789048144"^^xsd:double ;
        gpml:y            "706.7900622909483"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/a5b33/Point/f16ec6e669d2f26e669a77b3bff76f5f>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/a5b33> ;
        gpml:graphRef     "e92a9" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "908.5"^^xsd:double ;
        gpml:y            "1067.0"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/a6118>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:align           "Center" ;
        gpml:centerX         "687.5"^^xsd:double ;
        gpml:centerY         "1167.0"^^xsd:double ;
        gpml:color           "ff" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "10.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "a6118" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "Cu" ;
        gpml:type            "Metabolite" ;
        gpml:valign          "Middle" ;
        gpml:width           "33.0"^^xsd:double ;
        gpml:xrefDataSource  "HMDB" ;
        gpml:xrefId          "HMDB0000657" ;
        gpml:zorder          "32768"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id5d12dff3/Point/f596ddbca609bd72774029fbf718a5d>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id5d12dff3> ;
        gpml:graphRef     "e81dd" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "1238.666666666667"^^xsd:double ;
        gpml:y            "1187.333333333334"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idd37d0e73>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "idd37d0e73" ;
        gpml:hasAnchor      <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idd37d0e73/Anchor/d6342> ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idd37d0e73/Point/5edc9308e651a83869d6b052b2255a0a> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idd37d0e73/Point/a52ba3edd4b491bd12bd7663d00580ae> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Label/d10b5>
        rdf:type             gpml:Label ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:align           "Center" ;
        gpml:centerX         "1199.333333333335"^^xsd:double ;
        gpml:centerY         "1077.6666666666665"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "10.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "d10b5" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:href            "" ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "None" ;
        gpml:textlabel       "Aggregates" ;
        gpml:valign          "Middle" ;
        gpml:width           "70.6666666666666"^^xsd:double ;
        gpml:zorder          "28672"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id7d4f73cd/Point/139a6ccd89e3d6af9499cf9817e29b6f>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id7d4f73cd> ;
        gpml:graphRef     "e0fcd" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "804.9999999999998"^^xsd:double ;
        gpml:y            "982.366163432428"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/f8e7a>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:align           "Center" ;
        gpml:centerX         "853.99520383693"^^xsd:double ;
        gpml:centerY         "1078.5398329002144"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "10.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "f8e7a" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "SOD1" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "35.99040767386009"^^xsd:double ;
        gpml:xrefDataSource  "Entrez Gene" ;
        gpml:xrefId          "6647" ;
        gpml:zorder          "32836"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id709adf57/Point/5999a36205813a6f52935867a22375a4>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id709adf57> ;
        gpml:graphRef     "e5005" ;
        gpml:relX         "1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "712.0"^^xsd:double ;
        gpml:y            "314.0"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Label/e38ad>
        rdf:type             gpml:Label ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:align           "Center" ;
        gpml:centerX         "1349.0000000000005"^^xsd:double ;
        gpml:centerY         "1076.9999999999995"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "10.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "e38ad" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:href            "" ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "None" ;
        gpml:textlabel       "Impairment of\naxonal transport" ;
        gpml:valign          "Middle" ;
        gpml:width           "93.33333333333245"^^xsd:double ;
        gpml:zorder          "28672"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/e9f96>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:align           "Center" ;
        gpml:centerX         "213.83333333333334"^^xsd:double ;
        gpml:centerY         "132.33333333333331"^^xsd:double ;
        gpml:color           "ff" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "10.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "e9f96" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "NO" ;
        gpml:type            "Metabolite" ;
        gpml:valign          "Middle" ;
        gpml:width           "62.99999999999999"^^xsd:double ;
        gpml:xrefDataSource  "HMDB" ;
        gpml:xrefId          "HMDB0003378" ;
        gpml:zorder          "32768"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Label/accaa>
        rdf:type             gpml:Label ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:align           "Center" ;
        gpml:centerX         "738.1176470588232"^^xsd:double ;
        gpml:centerY         "123.20187609927703"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "10.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "accaa" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:href            "" ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "None" ;
        gpml:textlabel       "DNA damage" ;
        gpml:valign          "Middle" ;
        gpml:width           "80.0"^^xsd:double ;
        gpml:zorder          "28672"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idceff721/Point/b1aa6f7e67d2fd2e35a39bc2c68fcc44>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idceff721> ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "1340.0"^^xsd:double ;
        gpml:y            "689.8110782955976"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id28b00f54/Point/393822f214e75c940a2a7e283a764efa>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id28b00f54> ;
        gpml:graphRef     "c29ce" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "376.574051835096"^^xsd:double ;
        gpml:y            "934.9497760084338"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id4993787b/Point/8790f516c7a6e62ac582bf70899eec8a>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id4993787b> ;
        gpml:graphRef     "d4a30" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "1039.333333333333"^^xsd:double ;
        gpml:y            "1077.8731662335485"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id1de00d7a/Point/6e0a8d43aa2518213fff16c96db46c6a>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id1de00d7a> ;
        gpml:graphRef     "fbdfc" ;
        gpml:relX         "1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "782.6666666666654"^^xsd:double ;
        gpml:y            "872.5398329002154"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/ida704e090/Point/516873610703e3182bf645ec4b68a39e>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/ida704e090> ;
        gpml:graphRef     "d6fe8" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "893.7313974591672"^^xsd:double ;
        gpml:y            "266.43738656987307"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idfbf571ae/Point/da00963f7ea35cff0b11f1bd53dbb137>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idfbf571ae> ;
        gpml:graphRef     "a6f34" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "850.2"^^xsd:double ;
        gpml:y            "1077.0"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id17b01402>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "id17b01402" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id17b01402/Point/795377ad664f8df538a808b3b597a722> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id17b01402/Point/e99455dd85e40a8cf5417d08ee3c7620> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id1d08513f>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:color          "0" ;
        gpml:connectorType  "Elbow" ;
        gpml:graphId        "id1d08513f" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id1d08513f/Point/ddd54ef53264bf3c6e316d8841b75e68> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id1d08513f/Point/e93c6510633a9fecde87080ef20ec4c2> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id1d08513f/Point/33b742720c5400154244ee584fb6edb5> ;
        gpml:lineStyle      "Broken" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idd75808de/Point/97e28d59512080ae4890e7c7bef1c3eb>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idd75808de> ;
        gpml:graphRef     "b3274" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "876.416666666667"^^xsd:double ;
        gpml:y            "842.6231662335483"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id7bbfe1e0/Point/1576d1f318855f6ca355031982675d9d>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id7bbfe1e0> ;
        gpml:graphRef     "e7ea6" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "705.0"^^xsd:double ;
        gpml:y            "357.5891472868224"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id2bad9ea5/Point/4b829d51c096d627dd2fdcc2d4531bd0>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id2bad9ea5> ;
        gpml:graphRef     "c4c17" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "1038.333333333333"^^xsd:double ;
        gpml:y            "1109.3333333333335"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id89599c68/Point/3082bb6a0f2f1d76e6e9d998e8145537>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id89599c68> ;
        gpml:graphRef     "f6deb" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "656.0"^^xsd:double ;
        gpml:y            "1077.0"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/fcde2>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:align           "Center" ;
        gpml:centerX         "1079.333333333333"^^xsd:double ;
        gpml:centerY         "1045.5398329002146"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "10.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "fcde2" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "NEFL" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "80.0"^^xsd:double ;
        gpml:xrefDataSource  "Entrez Gene" ;
        gpml:xrefId          "4747" ;
        gpml:zorder          "32768"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idde65c6be>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:color          "0" ;
        gpml:connectorType  "Segmented" ;
        gpml:graphId        "idde65c6be" ;
        gpml:hasAnchor      <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idde65c6be/Anchor/edabf> ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idde65c6be/Point/7328bd1e9f8709580077cc0bb175f88> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idde65c6be/Point/a4a83253d95d2e864f12a05d9d5b8152> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idde65c6be/Point/87821fc2bd403598cbfc22aedbf20429> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Label/f559c>
        rdf:type             gpml:Label ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:align           "Center" ;
        gpml:centerX         "774.5"^^xsd:double ;
        gpml:centerY         "314.0"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "10.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "f559c" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:href            "" ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "None" ;
        gpml:textlabel       "tBid " ;
        gpml:valign          "Middle" ;
        gpml:width           "37.0"^^xsd:double ;
        gpml:zorder          "28672"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/f9f96/Point/dd8334cd1d031af5353fe7f83a97b48>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/f9f96> ;
        gpml:graphRef     "de780" ;
        gpml:relX         "1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "479.59800664451825"^^xsd:double ;
        gpml:y            "184.74363233665557"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id2949d535>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "id2949d535" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id2949d535/Point/a60d92c93621e173b488516560d5e8eb> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id2949d535/Point/5679a96f2bb692a149b4fd94fb787360> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id69896d2b>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:color          "0" ;
        gpml:connectorType  "Elbow" ;
        gpml:graphId        "id69896d2b" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id69896d2b/Point/8a6518d8d1eb2d223097b13c79a0d189> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id69896d2b/Point/593f1b15fd4b1d1801979be75fef2a46> ;
        gpml:lineStyle      "Broken" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Shape/a4d8e>
        rdf:type             gpml:shape ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:align           "Center" ;
        gpml:centerX         "1301.3333333333328"^^xsd:double ;
        gpml:centerY         "870.8731662335488"^^xsd:double ;
        gpml:color           "c0c0c0" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "10.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "a4d8e" ;
        gpml:height          "70.66666666666669"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "3.0"^^xsd:double ;
        gpml:shape           "0.0"^^xsd:double ;
        gpml:shapeType       "Oval" ;
        gpml:textlabel       "" ;
        gpml:valign          "Middle" ;
        gpml:width           "200.0"^^xsd:double ;
        gpml:zorder          "16384"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id19a072ea/Point/183efa6c796d14446c6c9253ccecbc70>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id19a072ea> ;
        gpml:graphRef     "f875f" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "1553.3493368014585"^^xsd:double ;
        gpml:y            "672.8320943002468"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/ida154c80d>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:color          "0" ;
        gpml:connectorType  "Curved" ;
        gpml:graphId        "ida154c80d" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/ida154c80d/Point/195d805478fb4c5a2396ceb99b4fd51c> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/ida154c80d/Point/918f861f1c3347d20427d9a2c0367ccc> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/ida154c80d/Point/6d5110c71c1d478ae8c17a686605a3a6> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id2c89d6cd/Point/e152776e0b695612e17e4d3970394af8>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id2c89d6cd> ;
        gpml:graphRef     "e7ea6" ;
        gpml:relX         "1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "762.1007751937984"^^xsd:double ;
        gpml:y            "357.5891472868224"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/ide9959d31/Point/43eb1fe50c4830ea630ae8f0c8170084>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/ide9959d31> ;
        gpml:graphRef     "ff83a" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "400.6190476190476"^^xsd:double ;
        gpml:y            "728.357142857143"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/ida154c80d/Point/918f861f1c3347d20427d9a2c0367ccc>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/ida154c80d> ;
        gpml:graphRef     "f6deb" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "676.0"^^xsd:double ;
        gpml:y            "1067.0"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id7c9c96e3/Anchor/eb6fd>
        rdf:type          gpml:Anchor ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id7c9c96e3> ;
        gpml:graphId      "eb6fd" ;
        gpml:position     "0.4"^^xsd:double ;
        gpml:shape        "None" .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id676d67d3/Point/bfe91c862409a7b72b81fa17c23450cb>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id676d67d3> ;
        gpml:graphRef     "ef623" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "637.0"^^xsd:double ;
        gpml:y            "1119.0"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/c620a>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:align           "Center" ;
        gpml:centerX         "362.00000000000273"^^xsd:double ;
        gpml:centerY         "934.497890295358"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "10.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "c620a" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "TNFR" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "65.33333333333309"^^xsd:double ;
        gpml:xrefDataSource  "Entrez Gene" ;
        gpml:xrefId          "7132" ;
        gpml:zorder          "32824"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id2949d535/Point/a60d92c93621e173b488516560d5e8eb>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id2949d535> ;
        gpml:graphRef     "c93d3" ;
        gpml:relX         "1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "175.371335504886"^^xsd:double ;
        gpml:y            "254.42996742671016"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/ida3cff5f4/Point/4ea9e6e726913d35e377de4200a4e2a2>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/ida3cff5f4> ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "1474.0"^^xsd:double ;
        gpml:y            "398.0379936031232"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/bcd7f>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:align           "Center" ;
        gpml:centerX         "731.8333333333329"^^xsd:double ;
        gpml:centerY         "1079.5398329002144"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "10.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "bcd7f" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "SOD1" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "44.33333333333417"^^xsd:double ;
        gpml:xrefDataSource  "Entrez Gene" ;
        gpml:xrefId          "6647" ;
        gpml:zorder          "32837"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id26259e54/Point/66c40335250bcbb840a6735c5ac5bc63>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id26259e54> ;
        gpml:graphRef     "ff83a" ;
        gpml:relX         "1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "442.0"^^xsd:double ;
        gpml:y            "728.357142857143"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id8c85cf83/Point/1cf0e9576430fb133774a1c33575211a>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id8c85cf83> ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "485.0"^^xsd:double ;
        gpml:y            "132.0"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Label/e33d8>
        rdf:type             gpml:Label ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:align           "Center" ;
        gpml:centerX         "1088.0"^^xsd:double ;
        gpml:centerY         "453.0"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "10.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "e33d8" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:href            "" ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "None" ;
        gpml:textlabel       "Increased ROS" ;
        gpml:valign          "Middle" ;
        gpml:width           "80.0"^^xsd:double ;
        gpml:zorder          "28672"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/ide9959d31/Anchor/faca6>
        rdf:type          gpml:Anchor ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/ide9959d31> ;
        gpml:graphId      "faca6" ;
        gpml:position     "0.7740349235295847"^^xsd:double ;
        gpml:shape        "None" .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Shape/c7a87>
        rdf:type             gpml:shape ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Group/e7d4a> ;
        gpml:align           "Center" ;
        gpml:centerX         "1727.0"^^xsd:double ;
        gpml:centerY         "101.0"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "c7a87" ;
        gpml:groupRef        "e7d4a" ;
        gpml:height          "16.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shape           "0.0"^^xsd:double ;
        gpml:shapeType       "Triangle" ;
        gpml:textlabel       "" ;
        gpml:valign          "Middle" ;
        gpml:width           "16.0"^^xsd:double ;
        gpml:zorder          "16384"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id7d4f73cd/Anchor/afcbe>
        rdf:type          gpml:Anchor ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id7d4f73cd> ;
        gpml:graphId      "afcbe" ;
        gpml:position     "0.890625"^^xsd:double ;
        gpml:shape        "None" .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id9c0ea925/Point/c36eb8716848fc441a93dd82b326bdc1>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id9c0ea925> ;
        gpml:graphRef     "a899e" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "646.0000985171715"^^xsd:double ;
        gpml:y            "184.86568173393195"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id9999669c>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "id9999669c" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id9999669c/Point/ad01556e22fd8d730757efe9c1139ee6> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id9999669c/Point/86fe90a2db0ac9ab1875e2e04230639a> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id117c419f/Point/ccdc533a8ae60da9c43e37c8e888e47b>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id117c419f> ;
        gpml:graphRef     "a0090" ;
        gpml:relX         "1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "821.0"^^xsd:double ;
        gpml:y            "1077.0"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idfe11c8d2>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:color          "0" ;
        gpml:connectorType  "Segmented" ;
        gpml:graphId        "idfe11c8d2" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idfe11c8d2/Point/deb057d0dc85d9cffe90b73be3a645ff> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idfe11c8d2/Point/17e9fbe641e6afdb68ace0c5af8a0c10> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idfe11c8d2/Point/93ba45eaeed1d6db8415c651d771dd51> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idfe11c8d2/Point/406c589c12f6051595944a3289db270d> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idd82ec964/Point/875afaf7aedf8d283a8c38a1169570bd>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idd82ec964> ;
        gpml:graphRef     "accaa" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "698.1176470588232"^^xsd:double ;
        gpml:y            "123.20187609927703"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id6a75a338/Point/5400321cc0a77118071bc3d54f1dc570>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id6a75a338> ;
        gpml:graphRef     "d4a30" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "1039.333333333333"^^xsd:double ;
        gpml:y            "1077.8731662335485"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/d4a30>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:align           "Center" ;
        gpml:centerX         "1079.333333333333"^^xsd:double ;
        gpml:centerY         "1077.8731662335485"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "10.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "d4a30" ;
        gpml:height          "22.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "NEFM" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "80.0"^^xsd:double ;
        gpml:xrefDataSource  "Entrez Gene" ;
        gpml:xrefId          "4741" ;
        gpml:zorder          "32768"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Label/a6f86>
        rdf:type             gpml:Label ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Group/f30d3> ;
        gpml:align           "Center" ;
        gpml:centerX         "938.0"^^xsd:double ;
        gpml:centerY         "415.0"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "10.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "a6f86" ;
        gpml:groupRef        "f64e8" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:href            "" ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "None" ;
        gpml:textlabel       "Low Ca²⁺ buffering capacity" ;
        gpml:valign          "Middle" ;
        gpml:width           "152.0"^^xsd:double ;
        gpml:zorder          "28672"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idfe11c8d2/Point/deb057d0dc85d9cffe90b73be3a645ff>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idfe11c8d2> ;
        gpml:graphRef     "dfe3d" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "1299.7093551316984"^^xsd:double ;
        gpml:y            "881.0263396911889"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idfe11c8d2/Point/406c589c12f6051595944a3289db270d>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idfe11c8d2> ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
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<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idedb1ca54/Point/9f1c3cdf618004363052a0914dd207d>
        rdf:type          gpml:Point ;
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        gpml:graphRef     "f875f" ;
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        gpml:x            "1553.3493368014585"^^xsd:double ;
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<http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/de780>
        rdf:type             gpml:DataNode ;
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        gpml:centerY         "184.74363233665557"^^xsd:double ;
        gpml:color           "ff" ;
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        gpml:fontDecoration  "Normal" ;
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        gpml:fontSize        "10.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "de780" ;
        gpml:height          "25.28571428571429"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "Reactive oxygen\nspecies (ROS)" ;
        gpml:type            "Metabolite" ;
        gpml:valign          "Middle" ;
        gpml:width           "87.59800664451825"^^xsd:double ;
        gpml:xrefDataSource  "ChEBI" ;
        gpml:xrefId          "CHEBI:26523" ;
        gpml:zorder          "32768"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idd46b0994/Point/d0a8cc16a4e0228ad8482e4828bc2ad0>
        rdf:type          gpml:Point ;
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        gpml:graphRef     "ff83a" ;
        gpml:relX         "1.0"^^xsd:double ;
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        gpml:x            "442.0"^^xsd:double ;
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<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/ide9959d31/Point/7c55d2922b1a9f2e6489b767aad604d6>
        rdf:type          gpml:Point ;
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        gpml:graphRef     "f9d1b" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "227.7876537997467"^^xsd:double ;
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<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id9206222b>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "id9206222b" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id9206222b/Point/b620cf0922c5c7c252dc318322069c03> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id9206222b/Point/337d092ad2f6d7d22089aaa2c12f3249> ;
        gpml:lineStyle      "Broken" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id8c85cf83/Point/7bef0423abf60d65ebf7b3ab70991167>
        rdf:type          gpml:Point ;
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        gpml:graphRef     "bd217" ;
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        gpml:x            "694.5098039215686"^^xsd:double ;
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<http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/f6282>
        rdf:type             gpml:DataNode ;
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        gpml:color           "0" ;
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        gpml:fontSize        "10.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "f6282" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "DAXX" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "53.33333333333303"^^xsd:double ;
        gpml:xrefDataSource  "Entrez Gene" ;
        gpml:xrefId          "1616" ;
        gpml:zorder          "32768"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/ida3cff5f4/Point/5ceef0c2a21c2121de8aebd5da5dc62c>
        rdf:type          gpml:Point ;
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        gpml:graphRef     "b6e6e" ;
        gpml:relX         "1.0"^^xsd:double ;
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        gpml:x            "899.2184873949584"^^xsd:double ;
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<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id94a8676c/Point/93f600995a9a4e3f0343378d1d4e4054>
        rdf:type          gpml:Point ;
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        gpml:relX         "0.0"^^xsd:double ;
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        gpml:x            "410.6666666666667"^^xsd:double ;
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<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/ida3cff5f4>
        rdf:type            gpml:Interaction ;
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        gpml:color          "0" ;
        gpml:connectorType  "Elbow" ;
        gpml:graphId        "ida3cff5f4" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/ida3cff5f4/Point/25311b0161f70c572597424120ec6a8b> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/ida3cff5f4/Point/5ceef0c2a21c2121de8aebd5da5dc62c> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/ida3cff5f4/Point/4ea9e6e726913d35e377de4200a4e2a2> ;
        gpml:lineStyle      "Broken" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/b55cc/Point/ad0a8dd1d07be4355687716a26e7b50b>
        rdf:type          gpml:Point ;
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        gpml:graphRef     "a1e19" ;
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<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id6a78f165/Point/b9f36a7e84235315951113464cbb3da2>
        rdf:type          gpml:Point ;
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        gpml:graphRef     "b69ab" ;
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        gpml:x            "918.6666666666666"^^xsd:double ;
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<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/a5b33/Point/2dca465a47fb23b864ac72e66129db43>
        rdf:type          gpml:Point ;
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        gpml:graphRef     "b24b0" ;
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<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Label/c9a4d>
        rdf:type             gpml:Label ;
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        gpml:color           "0" ;
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        gpml:graphId         "c9a4d" ;
        gpml:height          "20.0"^^xsd:double ;
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        gpml:lineStyle       "Solid" ;
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        gpml:shapeType       "None" ;
        gpml:textlabel       "Disturbance of\nmitochondrial respiration" ;
        gpml:valign          "Middle" ;
        gpml:width           "105.8823529411768"^^xsd:double ;
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<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idb3584e45>
        rdf:type            gpml:Interaction ;
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        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
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        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idb3584e45/Point/153b46cf919ab9f627c0e042cefb44dc> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idb3584e45/Point/f2f2bb41b7931e514f432fde09f78ae4> ;
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<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id751c8da1/Point/ee3a4787fb41c028923469f78cae30fe>
        rdf:type          gpml:Point ;
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        gpml:graphRef     "a1e19" ;
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<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/iddfc4ddf2>
        rdf:type            gpml:Interaction ;
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        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "iddfc4ddf2" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/iddfc4ddf2/Point/fd0d9312a9d5e5bf203a70c04fd8e06e> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/iddfc4ddf2/Point/b71880e08b46959fa7d93bd6c22a41dc> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
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<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id50769619>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "id50769619" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id50769619/Point/6833ea167c272e9411685b9f1affdf78> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id50769619/Point/e050aeb4a24feb91129b2694366e6aee> ;
        gpml:lineStyle      "Broken" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idf5c9eb78/Point/3a085b0d3628fcd687164bec7b62a82>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idf5c9eb78> ;
        gpml:graphRef     "e5005" ;
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<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id136847e9/Point/dbacad9973d2d7a478ce53e4da48ffaa>
        rdf:type          gpml:Point ;
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        gpml:relX         "0.0"^^xsd:double ;
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<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Comment/6df8a1bb053cb4570a8bc4deaacc3efa>
        rdf:type          gpml:Comment ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idb3584e45> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id8c85cf83> ;
        gpml:commentText  "Translocation" .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/ida0c052ab>
        rdf:type            gpml:Interaction ;
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        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/ida0c052ab/Point/51e8d45e729750a54d0c832a181c27d1> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/ida0c052ab/Point/7b11831d62d5e032b9ecb5cc1251805a> ;
        gpml:lineStyle      "Broken" ;
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        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idde65c6be/Point/7328bd1e9f8709580077cc0bb175f88>
        rdf:type          gpml:Point ;
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<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id1e1bab7c/Point/51d28491277458fbe1fa2043d5db3d45>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id1e1bab7c> ;
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<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id7c9c96e3/Point/938f9cccedbdf6a08b665d738cd32fad>
        rdf:type          gpml:Point ;
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        gpml:graphRef     "f6deb" ;
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<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/ide31a0350/Point/824c43a1f06d2dc45063702bb32a80c6>
        rdf:type          gpml:Point ;
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        gpml:relX         "0.0"^^xsd:double ;
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<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/ida90aa669/Point/23550e233687febef3401dbb49304b7d>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/ida90aa669> ;
        gpml:graphRef     "b06fe" ;
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<http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/a0d6a>
        rdf:type             gpml:DataNode ;
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        gpml:fontSize        "10.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
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        gpml:fontWeight      "Normal" ;
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        gpml:height          "20.0"^^xsd:double ;
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        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "BAX" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "50.0"^^xsd:double ;
        gpml:xrefDataSource  "Entrez Gene" ;
        gpml:xrefId          "581" ;
        gpml:zorder          "32816"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/b06fe>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:align           "Center" ;
        gpml:centerX         "1003.2377495462794"^^xsd:double ;
        gpml:centerY         "76.20309618803853"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "10.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "b06fe" ;
        gpml:height          "20.000000000000004"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "CYTC" ;
        gpml:type            "Protein" ;
        gpml:valign          "Middle" ;
        gpml:width           "57.16878402903801"^^xsd:double ;
        gpml:xrefDataSource  "UniProtKB" ;
        gpml:xrefId          "P01034" ;
        gpml:zorder          "32768"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idb6b067bd/Point/8bda44147427c4acbfe262f05295494>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idb6b067bd> ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "1502.0"^^xsd:double ;
        gpml:y            "369.1683067084016"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id2dedab80/Point/68f55b6083ca0326392b872b1405af94>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id2dedab80> ;
        gpml:graphRef     "bd217" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "676.0196078431372"^^xsd:double ;
        gpml:y            "982.366163432428"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/ida704e090>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "ida704e090" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/ida704e090/Point/e3632abba3c3601356cd0eadf5dd4256> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/ida704e090/Point/516873610703e3182bf645ec4b68a39e> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id6fc14d0a/Point/ae4b73b61a4b1be506d6f1670c9033d1>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id6fc14d0a> ;
        gpml:graphRef     "e0fcd" ;
        gpml:relX         "-0.5"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "816.2499999999998"^^xsd:double ;
        gpml:y            "992.366163432428"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idb3aea929/Point/ba25feaa2387d0f3494dfcae9eb6e61c>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idb3aea929> ;
        gpml:graphRef     "a22a5" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "996.0000000000005"^^xsd:double ;
        gpml:y            "881.5398329002153"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id2949d535/Point/5679a96f2bb692a149b4fd94fb787360>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id2949d535> ;
        gpml:graphRef     "edabf" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "166.352796424795"^^xsd:double ;
        gpml:y            "254.21792798264403"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id85aed399>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "id85aed399" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id85aed399/Point/8e1b0c01474e701970ff37b332557481> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id85aed399/Point/487672593da285da8e7ebc805fa58377> ;
        gpml:lineStyle      "Broken" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/e3646>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:align           "Center" ;
        gpml:centerX         "1260.778501628664"^^xsd:double ;
        gpml:centerY         "628.0846905537455"^^xsd:double ;
        gpml:color           "14961e" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Bold" ;
        gpml:graphId         "e3646" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "RoundedRectangle" ;
        gpml:textlabel       "Apoptosis" ;
        gpml:type            "Pathway" ;
        gpml:valign          "Middle" ;
        gpml:width           "80.0"^^xsd:double ;
        gpml:xrefDataSource  "WikiPathways" ;
        gpml:xrefId          "WP254" ;
        gpml:zorder          "32832"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id28b00f54/Point/4d9a6f5daea78e32ec265e9a3dcae7a8>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id28b00f54> ;
        gpml:graphRef     "c620a" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "362.00000000000273"^^xsd:double ;
        gpml:y            "944.497890295358"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id85aed399/Point/8e1b0c01474e701970ff37b332557481>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id85aed399> ;
        gpml:graphRef     "bb36d" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "208.45916114790225"^^xsd:double ;
        gpml:y            "1024.5398329002146"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/ffa60>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:align           "Center" ;
        gpml:centerX         "981.3333333333333"^^xsd:double ;
        gpml:centerY         "1148.6666666666665"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "10.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "ffa60" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "PRPH" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "52.666666666666515"^^xsd:double ;
        gpml:xrefDataSource  "Entrez Gene" ;
        gpml:xrefId          "5630" ;
        gpml:zorder          "32768"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/e92a9>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:align           "Center" ;
        gpml:centerX         "908.5"^^xsd:double ;
        gpml:centerY         "1077.0"^^xsd:double ;
        gpml:color           "ff" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "10.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "e92a9" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "OH" ;
        gpml:type            "Metabolite" ;
        gpml:valign          "Middle" ;
        gpml:width           "29.0"^^xsd:double ;
        gpml:xrefDataSource  "HMDB" ;
        gpml:xrefId          "HMDB0001039" ;
        gpml:zorder          "32768"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/e66bb>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:align           "Center" ;
        gpml:centerX         "1083.7386569872965"^^xsd:double ;
        gpml:centerY         "230.38402341057127"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "10.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "e66bb" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "BAD" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "48.0"^^xsd:double ;
        gpml:xrefDataSource  "Entrez Gene" ;
        gpml:xrefId          "572" ;
        gpml:zorder          "32817"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id6a75a338/Point/499986f8c27b61f118c7c49a51c75dfe>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id6a75a338> ;
        gpml:graphRef     "e92a9" ;
        gpml:relX         "1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "923.0"^^xsd:double ;
        gpml:y            "1077.0"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id94a8676c/Anchor/c29ce>
        rdf:type          gpml:Anchor ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id94a8676c> ;
        gpml:graphId      "c29ce" ;
        gpml:position     "0.26733348729900486"^^xsd:double ;
        gpml:shape        "None" .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/ed0c3>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Group/d820d> ;
        gpml:align           "Center" ;
        gpml:centerX         "858.4817275747506"^^xsd:double ;
        gpml:centerY         "204.98338870431908"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "10.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "ed0c3" ;
        gpml:groupRef        "d8f19" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "PPP3CC" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "80.0"^^xsd:double ;
        gpml:xrefDataSource  "Entrez Gene" ;
        gpml:xrefId          "5533" ;
        gpml:zorder          "32768"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Label/c28c5>
        rdf:type             gpml:Label ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:align           "Center" ;
        gpml:centerX         "453.02380952380963"^^xsd:double ;
        gpml:centerY         "585.8095238095239"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "10.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "c28c5" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:href            "" ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "None" ;
        gpml:textlabel       "Increase in\ncytosolic Ca²⁺" ;
        gpml:valign          "Middle" ;
        gpml:width           "91.0"^^xsd:double ;
        gpml:zorder          "32795"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idc2e2eee1/Anchor/c5b99>
        rdf:type          gpml:Anchor ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idc2e2eee1> ;
        gpml:graphId      "c5b99" ;
        gpml:position     "0.7735159530539221"^^xsd:double ;
        gpml:shape        "None" .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/c93d3>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:align           "Center" ;
        gpml:biopaxRef       "ea2" ;
        gpml:centerX         "152.371335504886"^^xsd:double ;
        gpml:centerY         "254.42996742671014"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "10.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "c93d3" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "EAAT2" ;
        gpml:type            "Protein" ;
        gpml:valign          "Middle" ;
        gpml:width           "46.0"^^xsd:double ;
        gpml:xrefDataSource  "UniProtKB" ;
        gpml:xrefId          "P43004" ;
        gpml:zorder          "32775"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id676d67d3/Point/35832b00dbcac11cf6435c6bf20d79d5>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id676d67d3> ;
        gpml:graphRef     "d6342" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "705.2333333333331"^^xsd:double ;
        gpml:y            "1130.0159331600858"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/State/cb758>
        rdf:type            gpml:State ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:color          "0" ;
        gpml:fillColor      "ffffff" ;
        gpml:graphId        "cb758" ;
        gpml:graphRef       "fefdb" ;
        gpml:height         "15.0"^^xsd:double ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:relX           "-0.9403558034839316"^^xsd:double ;
        gpml:relY           "-0.8449612403100787"^^xsd:double ;
        gpml:shapeType      "Triangle" ;
        gpml:stateOf        <http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/fefdb> ;
        gpml:stateType      "Unknown" ;
        gpml:textlabel      "" ;
        gpml:width          "15.0"^^xsd:double ;
        gpml:zorder         "32813"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id3cd23c9/Point/fce0343460a8f27d9aa7232526b25d2e>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id3cd23c9> ;
        gpml:graphRef     "f9d1b" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "179.2876537997467"^^xsd:double ;
        gpml:y            "675.5717238486789"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id2c89d6cd/Point/4dee1c60801324531078738ca2b1f335>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id2c89d6cd> ;
        gpml:graphRef     "c9a4d" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "853.4842532294219"^^xsd:double ;
        gpml:y            "357.18586574460085"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/ida1e5ab90/Point/b32473ce3a15e4b373abaf33051c2f17>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/ida1e5ab90> ;
        gpml:graphRef     "fc1ca" ;
        gpml:relX         "1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "1085.9859292554222"^^xsd:double ;
        gpml:y            "693.5331248778589"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id142719ee/Point/eba1de28f5174788c51a8ec899562bbf>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id142719ee> ;
        gpml:graphRef     "fbdfc" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "718.6666666666654"^^xsd:double ;
        gpml:y            "872.5398329002154"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idc2e2eee1/Point/9f76dbf219d779ee6e963bc9dcea2d88>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idc2e2eee1> ;
        gpml:graphRef     "f559c" ;
        gpml:relX         "1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "793.0"^^xsd:double ;
        gpml:y            "314.0"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id9999669c/Point/ad01556e22fd8d730757efe9c1139ee6>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id9999669c> ;
        gpml:graphRef     "b7cd3" ;
        gpml:relX         "1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "1158.8114657841352"^^xsd:double ;
        gpml:y            "65.90775845221802"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/b6e6e>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:align           "Center" ;
        gpml:centerX         "859.2184873949584"^^xsd:double ;
        gpml:centerY         "123.24389290599953"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "10.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "b6e6e" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "TP53" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "80.0"^^xsd:double ;
        gpml:xrefDataSource  "Entrez Gene" ;
        gpml:xrefId          "7157" ;
        gpml:zorder          "32780"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/dea3c>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Group/b3274> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:align           "Center" ;
        gpml:centerX         "876.416666666667"^^xsd:double ;
        gpml:centerY         "864.6231662335483"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "10.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "dea3c" ;
        gpml:groupRef        "faf2f" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "MKK3" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "80.0"^^xsd:double ;
        gpml:xrefDataSource  "Entrez Gene" ;
        gpml:xrefId          "5605" ;
        gpml:zorder          "32768"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idceff721/Point/7152a79482257e21237e8d61557e9b30>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idceff721> ;
        gpml:graphRef     "f875f" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "1553.3493368014585"^^xsd:double ;
        gpml:y            "672.8320943002468"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/b55cc>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "b55cc" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/b55cc/Point/15f45605daae18403b3a0172b7721d85> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/b55cc/Point/ad0a8dd1d07be4355687716a26e7b50b> ;
        gpml:lineStyle      "Broken" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "32800"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/ida0c052ab/Point/7b11831d62d5e032b9ecb5cc1251805a>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/ida0c052ab> ;
        gpml:graphRef     "f7b4d" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "1088.5"^^xsd:double ;
        gpml:y            "397.0"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id58649f3e>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "id58649f3e" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id58649f3e/Point/17ece6d7131461bf9a8c714950f48eed> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id58649f3e/Point/7fa56b6715d26a66efc5044d86a3d659> ;
        gpml:lineStyle      "Broken" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Group/e7d4a>
        rdf:type          gpml:Group ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:groupId      "e7d4a" ;
        gpml:style        "Group" .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/d6fe8>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:align           "Center" ;
        gpml:centerX         "893.7313974591672"^^xsd:double ;
        gpml:centerY         "255.71869328493653"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "10.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "d6fe8" ;
        gpml:height          "21.43738656987307"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "BCL2" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "43.46279491833434"^^xsd:double ;
        gpml:xrefDataSource  "Entrez Gene" ;
        gpml:xrefId          "596" ;
        gpml:zorder          "32814"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/b676b>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:align           "Center" ;
        gpml:centerX         "1003.2377495462791"^^xsd:double ;
        gpml:centerY         "49.05901895641981"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "10.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "b676b" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "APAF1" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "57.16878402903804"^^xsd:double ;
        gpml:xrefDataSource  "Entrez Gene" ;
        gpml:xrefId          "317" ;
        gpml:zorder          "32783"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/ida90aa669/Point/968757e91fbdf8af9d64ef142ed2c59a>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/ida90aa669> ;
        gpml:graphRef     "b7cd3" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "1094.8892921960069"^^xsd:double ;
        gpml:y            "65.90775845221802"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id676d67d3>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "id676d67d3" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id676d67d3/Point/bfe91c862409a7b72b81fa17c23450cb> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id676d67d3/Point/35832b00dbcac11cf6435c6bf20d79d5> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id19a072ea/Point/d2c9dba13917a728aad556c931edb3cf>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id19a072ea> ;
        gpml:graphRef     "f7b4d" ;
        gpml:relX         "1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "1140.0"^^xsd:double ;
        gpml:y            "415.5"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id2dedab80/Anchor/a56bc>
        rdf:type          gpml:Anchor ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id2dedab80> ;
        gpml:graphId      "a56bc" ;
        gpml:position     "0.4824115580448432"^^xsd:double ;
        gpml:shape        "None" .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id6fcdb47/Point/ca18f2d1a545f5c18bf17fbd4c012009>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id6fcdb47> ;
        gpml:graphRef     "bb36d" ;
        gpml:relX         "1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "272.45916114790293"^^xsd:double ;
        gpml:y            "1024.5398329002146"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/f2d32>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:align           "Center" ;
        gpml:centerX         "522.6666666666667"^^xsd:double ;
        gpml:centerY         "982.6830817162138"^^xsd:double ;
        gpml:color           "ff" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "10.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "f2d32" ;
        gpml:height          "20.633836567572416"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "L-Arginine" ;
        gpml:type            "Metabolite" ;
        gpml:valign          "Middle" ;
        gpml:width           "56.666666666666515"^^xsd:double ;
        gpml:xrefDataSource  "HMDB" ;
        gpml:xrefId          "HMDB0000517" ;
        gpml:zorder          "32773"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id8abdb052/Point/190547e0b310af737b339853ab3916cc>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id8abdb052> ;
        gpml:graphRef     "d6b95" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "925.7333333333331"^^xsd:double ;
        gpml:y            "1020.5689645528762"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/f04ac>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:align           "Center" ;
        gpml:centerX         "69.5"^^xsd:double ;
        gpml:centerY         "675.6742596810934"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "10.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "f04ac" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "L-Glutamic acid" ;
        gpml:type            "Metabolite" ;
        gpml:valign          "Middle" ;
        gpml:width           "97.0"^^xsd:double ;
        gpml:xrefDataSource  "HMDB" ;
        gpml:xrefId          "HMDB0000148" ;
        gpml:zorder          "32792"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idac7d1d20>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "idac7d1d20" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idac7d1d20/Point/54aa78206794b3bcbcb7c8e052acf1b0> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idac7d1d20/Point/b931b1f07f47c508ff4dacff8b02b0d3> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idd6d367a2/Point/eb616685ae4f57f716983ab20e47477d>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idd6d367a2> ;
        gpml:graphRef     "f433a" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "825.0"^^xsd:double ;
        gpml:y            "1116.6"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/b5cbd>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:align           "Center" ;
        gpml:centerX         "236.1162790697675"^^xsd:double ;
        gpml:centerY         "787.8062015503874"^^xsd:double ;
        gpml:color           "14961e" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Bold" ;
        gpml:graphId         "b5cbd" ;
        gpml:height          "34.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "RoundedRectangle" ;
        gpml:textlabel       "Synaptic transmission,\nglutamatergic" ;
        gpml:type            "Pathway" ;
        gpml:valign          "Middle" ;
        gpml:width           "150.0"^^xsd:double ;
        gpml:xrefDataSource  "WikiPathways" ;
        gpml:xrefId          "WP2267" ;
        gpml:zorder          "32768"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id7d4f73cd/Point/35ac40a3f8313ccf59f560d8251d2268>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id7d4f73cd> ;
        gpml:graphRef     "bd217" ;
        gpml:relX         "1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "713.0"^^xsd:double ;
        gpml:y            "982.366163432428"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idfbf571ae/Point/e3ddace8e51c543ec99017404c485ac3>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idfbf571ae> ;
        gpml:graphRef     "f8e7a" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "853.99520383693"^^xsd:double ;
        gpml:y            "1068.5398329002144"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/b7cd3>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:align           "Center" ;
        gpml:centerX         "1126.850378990071"^^xsd:double ;
        gpml:centerY         "65.90775845221802"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "10.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "b7cd3" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "CASP9" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "63.92217358812837"^^xsd:double ;
        gpml:xrefDataSource  "Entrez Gene" ;
        gpml:xrefId          "842" ;
        gpml:zorder          "32785"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id8c85cf83/Point/e01f63bffd78916a6c8ab5673a25e7b6>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id8c85cf83> ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "485.0"^^xsd:double ;
        gpml:y            "1052.0"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Label/eaa70>
        rdf:type             gpml:Label ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:align           "Center" ;
        gpml:centerX         "592.798319327731"^^xsd:double ;
        gpml:centerY         "288.7564979480162"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "10.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "eaa70" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:href            "" ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "None" ;
        gpml:textlabel       "Activation" ;
        gpml:valign          "Middle" ;
        gpml:width           "80.0"^^xsd:double ;
        gpml:zorder          "32829"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idceff721>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:color          "0" ;
        gpml:connectorType  "Elbow" ;
        gpml:graphId        "idceff721" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idceff721/Point/b1aa6f7e67d2fd2e35a39bc2c68fcc44> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idceff721/Point/2e5cd9a7156e1e6a79a03f17e9b7142d> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idceff721/Point/7152a79482257e21237e8d61557e9b30> ;
        gpml:lineStyle      "Broken" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idb6b067bd/Point/8ca3ff53bd86da17111fc88ef0ec3507>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idb6b067bd> ;
        gpml:graphRef     "a20e1" ;
        gpml:relX         "1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "1258.8577529015274"^^xsd:double ;
        gpml:y            "65.50451911655637"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/f7616>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:align           "Center" ;
        gpml:centerX         "358.0121640307662"^^xsd:double ;
        gpml:centerY         "729.6582138193121"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "10.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "f7616" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "GRIA1" ;
        gpml:type            "Protein" ;
        gpml:valign          "Middle" ;
        gpml:width           "47.04284658005098"^^xsd:double ;
        gpml:xrefDataSource  "Entrez Gene" ;
        gpml:xrefId          "2890" ;
        gpml:zorder          "32825"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id26259e54>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:color          "0" ;
        gpml:connectorType  "Elbow" ;
        gpml:graphId        "id26259e54" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id26259e54/Point/2ff6cb254f4d58bfa646637b27304bf2> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id26259e54/Point/45801dddf71b0d51fa0109230d0656cd> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id26259e54/Point/66c40335250bcbb840a6735c5ac5bc63> ;
        gpml:lineStyle      "Broken" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id69b8a250/Point/aa96088af772e47dd775523e4a46249b>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id69b8a250> ;
        gpml:graphRef     "a0090" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "801.0"^^xsd:double ;
        gpml:y            "1087.0"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id2bad9ea5>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "id2bad9ea5" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id2bad9ea5/Point/fbab06ea23cdb90ef8417f3650f4f041> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id2bad9ea5/Point/4b829d51c096d627dd2fdcc2d4531bd0> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/a0090>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:align           "Center" ;
        gpml:centerX         "801.0"^^xsd:double ;
        gpml:centerY         "1077.0"^^xsd:double ;
        gpml:color           "ff" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "10.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "a0090" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "H₂O₂" ;
        gpml:type            "Metabolite" ;
        gpml:valign          "Middle" ;
        gpml:width           "40.0"^^xsd:double ;
        gpml:xrefDataSource  "HMDB" ;
        gpml:xrefId          "HMDB0003125" ;
        gpml:zorder          "32768"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/b24b0>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:align           "Center" ;
        gpml:centerX         "813.907530454042"^^xsd:double ;
        gpml:centerY         "1033.7436323366555"^^xsd:double ;
        gpml:color           "ff" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "10.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "b24b0" ;
        gpml:height          "25.28571428571429"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "Reactive oxygen species \n(ROS)" ;
        gpml:type            "Metabolite" ;
        gpml:valign          "Middle" ;
        gpml:width           "115.0"^^xsd:double ;
        gpml:xrefDataSource  "ChEBI" ;
        gpml:xrefId          "CHEBI:26523" ;
        gpml:zorder          "32833"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id6fc14d0a/Point/c1fcedeff16048c020bf6dddfa66d0e8>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id6fc14d0a> ;
        gpml:graphRef     "b24b0" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "813.907530454042"^^xsd:double ;
        gpml:y            "1021.1007751937984"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/bd217>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:align           "Center" ;
        gpml:centerX         "694.5098039215686"^^xsd:double ;
        gpml:centerY         "982.366163432428"^^xsd:double ;
        gpml:color           "ff" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "10.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "bd217" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "NO" ;
        gpml:type            "Metabolite" ;
        gpml:valign          "Middle" ;
        gpml:width           "36.98039215686276"^^xsd:double ;
        gpml:xrefDataSource  "HMDB" ;
        gpml:xrefId          "HMDB0003378" ;
        gpml:zorder          "32772"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id8197ddde/Point/b8b6a2bd1a38b234b5d95a49cb6c6182>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id8197ddde> ;
        gpml:graphRef     "de780" ;
        gpml:relX         "1.0"^^xsd:double ;
        gpml:relY         "-0.5"^^xsd:double ;
        gpml:x            "479.59800664451825"^^xsd:double ;
        gpml:y            "178.42220376522698"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/e82f7>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:align           "Center" ;
        gpml:centerX         "520.0"^^xsd:double ;
        gpml:centerY         "315.0"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "10.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "e82f7" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "CASP1" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "48.0"^^xsd:double ;
        gpml:xrefDataSource  "Entrez Gene" ;
        gpml:xrefId          "834" ;
        gpml:zorder          "32810"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id2dedab80/Point/c20641eda94c56ed6243dfc7ba6db7ff>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id2dedab80> ;
        gpml:graphRef     "f2d32" ;
        gpml:relX         "1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "551.0"^^xsd:double ;
        gpml:y            "982.6830817162138"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id69896d2b/Point/8a6518d8d1eb2d223097b13c79a0d189>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id69896d2b> ;
        gpml:graphRef     "ff83a" ;
        gpml:relX         "1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "442.0"^^xsd:double ;
        gpml:y            "728.357142857143"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/a20e1>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:align           "Center" ;
        gpml:centerX         "1227.6902194634679"^^xsd:double ;
        gpml:centerY         "65.50451911655637"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "10.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "a20e1" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "CASP3" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "62.335066876119065"^^xsd:double ;
        gpml:xrefDataSource  "Entrez Gene" ;
        gpml:xrefId          "836" ;
        gpml:zorder          "32784"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id6fcdb47/Point/9f8907a1555355b335444189567271b2>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id6fcdb47> ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "634.0"^^xsd:double ;
        gpml:y            "1025.0"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/b0f78>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Group/d820d> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:align           "Center" ;
        gpml:centerX         "858.4817275747502"^^xsd:double ;
        gpml:centerY         "184.98338870431908"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "10.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "b0f78" ;
        gpml:groupRef        "d8f19" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "PPP3CB" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "80.0"^^xsd:double ;
        gpml:xrefDataSource  "Entrez Gene" ;
        gpml:xrefId          "5532" ;
        gpml:zorder          "32768"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/a5d0f>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "a5d0f" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/a5d0f/Point/496c9a70aa63863d18ca0f8560f6d4c0> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/a5d0f/Point/e8a9dae9e93e9bfa9b877cc98f1c63a7> ;
        gpml:lineStyle      "Broken" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "32801"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id89599c68>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "id89599c68" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id89599c68/Point/be665ddb9705bc52976a45d159113bf3> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id89599c68/Point/3082bb6a0f2f1d76e6e9d998e8145537> ;
        gpml:lineStyle      "Broken" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/ide31a0350>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:color          "0" ;
        gpml:connectorType  "Segmented" ;
        gpml:graphId        "ide31a0350" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/ide31a0350/Point/2376692956c202649b6f5c27f8078ff5> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/ide31a0350/Point/7fad32e4f99aea430446836b505aa6f5> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/ide31a0350/Point/208539f2b1c4761ab8154d22d755a5d3> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/ide31a0350/Point/824c43a1f06d2dc45063702bb32a80c6> ;
        gpml:lineStyle      "Broken" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Shape/ec332>
        rdf:type             gpml:shape ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Group/e7d4a> ;
        gpml:align           "Left" ;
        gpml:centerX         "1809.5"^^xsd:double ;
        gpml:centerY         "105.5"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Bold" ;
        gpml:graphId         "ec332" ;
        gpml:groupRef        "e7d4a" ;
        gpml:height          "99.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shape           "0.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "Legend" ;
        gpml:valign          "Top" ;
        gpml:width           "223.0"^^xsd:double ;
        gpml:zorder          "16384"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id58649f3e/Point/7fa56b6715d26a66efc5044d86a3d659>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id58649f3e> ;
        gpml:graphRef     "db1b0" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "1417.9999999999914"^^xsd:double ;
        gpml:y            "1138.3333333333335"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id6a78f165>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "id6a78f165" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id6a78f165/Point/f93ed51351ee80ec16a3d974169d2f7a> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id6a78f165/Point/b9f36a7e84235315951113464cbb3da2> ;
        gpml:lineStyle      "Broken" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id4993787b/Point/8b94c069feb24a28d87ac9e05d356f15>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id4993787b> ;
        gpml:graphRef     "e0fcd" ;
        gpml:relX         "1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "849.9999999999998"^^xsd:double ;
        gpml:y            "982.366163432428"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/e257e>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:align           "Center" ;
        gpml:centerX         "1181.5256608373975"^^xsd:double ;
        gpml:centerY         "673.2236057008387"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "10.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "e257e" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "CASP12" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "65.36664692286695"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000204403" ;
        gpml:zorder          "32821"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/ide31a0350/Point/208539f2b1c4761ab8154d22d755a5d3>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/ide31a0350> ;
        gpml:graphRef     "de780" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "435.7990033222591"^^xsd:double ;
        gpml:y            "197.3864894795127"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idde65c6be/Anchor/edabf>
        rdf:type          gpml:Anchor ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idde65c6be> ;
        gpml:graphId      "edabf" ;
        gpml:position     "0.8875061883621126"^^xsd:double ;
        gpml:shape        "None" .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Label/fc1ca>
        rdf:type             gpml:Label ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:align           "Center" ;
        gpml:centerX         "1055.5433522246103"^^xsd:double ;
        gpml:centerY         "693.5331248778589"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "10.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "fc1ca" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:href            "" ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "None" ;
        gpml:textlabel       "ER stress" ;
        gpml:valign          "Middle" ;
        gpml:width           "60.88515406162378"^^xsd:double ;
        gpml:zorder          "32799"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idf5c9eb78>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "idf5c9eb78" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idf5c9eb78/Point/3a085b0d3628fcd687164bec7b62a82> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idf5c9eb78/Point/473fabf1eb92d290856c7ff7019e5624> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id709adf57/Point/a1b9962d2ab7d3115240a41a93e44eee>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id709adf57> ;
        gpml:graphRef     "f559c" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "756.0"^^xsd:double ;
        gpml:y            "314.0"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Shape/a8c09>
        rdf:type             gpml:shape ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:align           "Center" ;
        gpml:centerX         "70.0"^^xsd:double ;
        gpml:centerY         "699.4242596810934"^^xsd:double ;
        gpml:color           "c0c0c0" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "10.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "a8c09" ;
        gpml:height          "128.5"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "3.0"^^xsd:double ;
        gpml:shape           "0.0"^^xsd:double ;
        gpml:shapeType       "RoundedRectangle" ;
        gpml:textlabel       "Presynaptic neuron" ;
        gpml:valign          "Middle" ;
        gpml:width           "124.0"^^xsd:double ;
        gpml:zorder          "32769"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/State/da777>
        rdf:type            gpml:State ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:color          "0" ;
        gpml:fillColor      "ffffff" ;
        gpml:graphId        "da777" ;
        gpml:graphRef       "c4c17" ;
        gpml:height         "15.0"^^xsd:double ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:relX           "-1.0"^^xsd:double ;
        gpml:relY           "-0.8604651162790333"^^xsd:double ;
        gpml:shapeType      "Triangle" ;
        gpml:stateOf        <http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/c4c17> ;
        gpml:stateType      "Unknown" ;
        gpml:textlabel      "" ;
        gpml:width          "15.0"^^xsd:double ;
        gpml:zorder         "32769"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idceff721/Point/2e5cd9a7156e1e6a79a03f17e9b7142d>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idceff721> ;
        gpml:graphRef     "f3615" ;
        gpml:relX         "1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "1214.93789048144"^^xsd:double ;
        gpml:y            "706.7900622909483"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id50769619/Point/6833ea167c272e9411685b9f1affdf78>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id50769619> ;
        gpml:graphRef     "e257e" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "1148.842337375964"^^xsd:double ;
        gpml:y            "673.2236057008387"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id5d12dff3/Point/dffaf95d6d30f8732a052d2c0e548d25>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id5d12dff3> ;
        gpml:graphRef     "d1b7a" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "1192.0"^^xsd:double ;
        gpml:y            "1145.9999999999995"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Label/f7b4d>
        rdf:type             gpml:Label ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:align           "Center" ;
        gpml:centerX         "1088.5"^^xsd:double ;
        gpml:centerY         "415.5"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "10.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "f7b4d" ;
        gpml:height          "37.0"^^xsd:double ;
        gpml:href            "" ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "None" ;
        gpml:textlabel       "ATP depletion Fall in\nmitochondrial\nmembrane potential" ;
        gpml:valign          "Middle" ;
        gpml:width           "103.0"^^xsd:double ;
        gpml:zorder          "28672"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/a67f7>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:align           "Center" ;
        gpml:centerX         "859.5"^^xsd:double ;
        gpml:centerY         "94.5"^^xsd:double ;
        gpml:color           "14961e" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Bold" ;
        gpml:graphId         "a67f7" ;
        gpml:height          "17.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "RoundedRectangle" ;
        gpml:textlabel       "p53 signaling pathway" ;
        gpml:type            "Pathway" ;
        gpml:valign          "Middle" ;
        gpml:width           "145.0"^^xsd:double ;
        gpml:xrefDataSource  "WikiPathways" ;
        gpml:xrefId          "WP707" ;
        gpml:zorder          "32768"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Group/f30d3>
        rdf:type          gpml:Group ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:graphId      "f30d3" ;
        gpml:groupId      "f64e8" ;
        gpml:style        "Group" .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/bcc7f>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:color          "999999" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "bcc7f" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/bcc7f/Point/3c76226d8f5c65216944b93aafd7b741> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/bcc7f/Point/5fc3205c503f279d6c0a5a9c028305f2> ;
        gpml:lineStyle      "Broken" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "32834"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/State/e9914>
        rdf:type            gpml:State ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:color          "0" ;
        gpml:fillColor      "ffffff" ;
        gpml:graphId        "e9914" ;
        gpml:graphRef       "f8e7a" ;
        gpml:height         "15.0"^^xsd:double ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:relX           "-1.0"^^xsd:double ;
        gpml:relY           "-1.0"^^xsd:double ;
        gpml:shapeType      "Triangle" ;
        gpml:stateOf        <http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/f8e7a> ;
        gpml:stateType      "Unknown" ;
        gpml:textlabel      "" ;
        gpml:width          "15.0"^^xsd:double ;
        gpml:zorder         "32837"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/fd4bd>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:align           "Center" ;
        gpml:centerX         "953.9618874773143"^^xsd:double ;
        gpml:centerY         "244.45009074410166"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "10.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "fd4bd" ;
        gpml:height          "20.900181488203316"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "BCL2L1" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "48.0762250453713"^^xsd:double ;
        gpml:xrefDataSource  "Entrez Gene" ;
        gpml:xrefId          "598" ;
        gpml:zorder          "32815"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id17b01402/Point/e99455dd85e40a8cf5417d08ee3c7620>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id17b01402> ;
        gpml:graphRef     "b69ab" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "838.6666666666666"^^xsd:double ;
        gpml:y            "547.7692024990812"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idd82ec964>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "idd82ec964" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idd82ec964/Point/875afaf7aedf8d283a8c38a1169570bd> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idd82ec964/Point/4e40f3e087731a2a2feb4ee9a032e2f1> ;
        gpml:lineStyle      "Broken" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id69b8a250/Point/c9c2796182d59e58bae2d64a34df5188>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id69b8a250> ;
        gpml:graphRef     "d81a7" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "861.0"^^xsd:double ;
        gpml:y            "1161.0"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id4993787b>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "id4993787b" ;
        gpml:hasAnchor      <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id4993787b/Anchor/d6b95> ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id4993787b/Point/8790f516c7a6e62ac582bf70899eec8a> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id4993787b/Point/8b94c069feb24a28d87ac9e05d356f15> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idd46b0994>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "idd46b0994" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idd46b0994/Point/d0a8cc16a4e0228ad8482e4828bc2ad0> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idd46b0994/Point/33871990b37b475c6f81354bdf0d7767> ;
        gpml:lineStyle      "Broken" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id142719ee/Point/1ed081588ff9b56e2381d90acbff3236>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id142719ee> ;
        gpml:graphRef     "f6282" ;
        gpml:relX         "1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "673.333333333333"^^xsd:double ;
        gpml:y            "872.8731662335496"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id719c925/Point/a1ad7ebbf25b42c2f87ed84cc9c8b137>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id719c925> ;
        gpml:graphRef     "de780" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "392.0"^^xsd:double ;
        gpml:y            "184.74363233665557"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idf5c9eb78/Point/473fabf1eb92d290856c7ff7019e5624>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idf5c9eb78> ;
        gpml:graphRef     "e82f7" ;
        gpml:relX         "1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "544.0"^^xsd:double ;
        gpml:y            "315.0"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id7c9c96e3>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "id7c9c96e3" ;
        gpml:hasAnchor      <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id7c9c96e3/Anchor/eb6fd> ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id7c9c96e3/Point/938f9cccedbdf6a08b665d738cd32fad> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id7c9c96e3/Point/76adf11deb402d2b365b05dcd0ab2dcd> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Label/a5860>
        rdf:type             gpml:Label ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:align           "Center" ;
        gpml:centerX         "1119.0"^^xsd:double ;
        gpml:centerY         "313.0"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "10.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "a5860" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:href            "" ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "None" ;
        gpml:textlabel       "Mitochondrial dysfunction" ;
        gpml:valign          "Middle" ;
        gpml:width           "126.0"^^xsd:double ;
        gpml:zorder          "28672"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/ide31a0350/Point/7fad32e4f99aea430446836b505aa6f5>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/ide31a0350> ;
        gpml:graphRef     "e33d8" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "1088.0"^^xsd:double ;
        gpml:y            "463.0"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id8abdb052>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "id8abdb052" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id8abdb052/Point/190547e0b310af737b339853ab3916cc> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id8abdb052/Point/d1146242e421b7baecf55d01ca833e59> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Shape/edd98>
        rdf:type             gpml:shape ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:align           "Center" ;
        gpml:centerX         "1009.3420987348054"^^xsd:double ;
        gpml:centerY         "639.3134024251248"^^xsd:double ;
        gpml:color           "c0c0c0" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "10.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "edd98" ;
        gpml:height          "1185.3731951497505"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "3.0"^^xsd:double ;
        gpml:shape           "0.0"^^xsd:double ;
        gpml:shapeType       "RoundedRectangle" ;
        gpml:textlabel       "Motor neuron" ;
        gpml:valign          "Middle" ;
        gpml:width           "1285.3158025303892"^^xsd:double ;
        gpml:zorder          "32771"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id17b01402/Point/795377ad664f8df538a808b3b597a722>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id17b01402> ;
        gpml:graphRef     "e7ea6" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "733.5503875968992"^^xsd:double ;
        gpml:y            "367.5891472868224"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id1de00d7a/Anchor/f68e5>
        rdf:type          gpml:Anchor ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id1de00d7a> ;
        gpml:graphId      "f68e5" ;
        gpml:position     "0.4"^^xsd:double ;
        gpml:shape        "None" .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/e777d>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Group/f30d3> ;
        gpml:align           "Center" ;
        gpml:centerX         "855.8095238095237"^^xsd:double ;
        gpml:centerY         "415.714285714286"^^xsd:double ;
        gpml:color           "ff" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "10.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "e777d" ;
        gpml:groupRef        "f64e8" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "Ca²⁺" ;
        gpml:type            "Metabolite" ;
        gpml:valign          "Middle" ;
        gpml:width           "32.38095238095252"^^xsd:double ;
        gpml:xrefDataSource  "HMDB" ;
        gpml:xrefId          "HMDB0000464" ;
        gpml:zorder          "32830"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Label/fa573>
        rdf:type             gpml:Label ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:align           "Center" ;
        gpml:centerX         "1224.798319327731"^^xsd:double ;
        gpml:centerY         "31.75649794801624"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "10.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "fa573" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:href            "" ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "None" ;
        gpml:textlabel       "Activation" ;
        gpml:valign          "Middle" ;
        gpml:width           "80.0"^^xsd:double ;
        gpml:zorder          "32787"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/f9d1b>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:align           "Center" ;
        gpml:centerX         "227.7876537997467"^^xsd:double ;
        gpml:centerY         "675.5717238486789"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "10.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "f9d1b" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "L-Glutamic acid" ;
        gpml:type            "Metabolite" ;
        gpml:valign          "Middle" ;
        gpml:width           "97.0"^^xsd:double ;
        gpml:xrefDataSource  "HMDB" ;
        gpml:xrefId          "HMDB0000148" ;
        gpml:zorder          "32776"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id94a8676c>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:color          "0" ;
        gpml:connectorType  "Segmented" ;
        gpml:graphId        "id94a8676c" ;
        gpml:hasAnchor      <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id94a8676c/Anchor/c29ce> ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id94a8676c/Point/ee8ca04ab66111fe203738b9c4b40a08> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id94a8676c/Point/e582665bef98f5ddb6301df1bc5b900a> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id94a8676c/Point/e5683be5cb31a023a2e43cc0c500ef0d> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id94a8676c/Point/93f600995a9a4e3f0343378d1d4e4054> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idfe11c8d2/Point/93ba45eaeed1d6db8415c651d771dd51>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idfe11c8d2> ;
        gpml:graphRef     "aeb39" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "611.0308123249297"^^xsd:double ;
        gpml:y            "942.8451550290667"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/f2714>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:align           "Center" ;
        gpml:centerX         "1120.6666666666633"^^xsd:double ;
        gpml:centerY         "822.4365831167743"^^xsd:double ;
        gpml:color           "14961e" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Bold" ;
        gpml:graphId         "f2714" ;
        gpml:height          "15.126833766451458"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "RoundedRectangle" ;
        gpml:textlabel       "MAPK signaling pathway" ;
        gpml:type            "Pathway" ;
        gpml:valign          "Middle" ;
        gpml:width           "174.66666666666674"^^xsd:double ;
        gpml:xrefDataSource  "WikiPathways" ;
        gpml:xrefId          "WP382" ;
        gpml:zorder          "32768"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id136847e9/Point/9fed4b1e4289be5117c53410e09994ae>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id136847e9> ;
        gpml:graphRef     "b7cd3" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "1094.8892921960069"^^xsd:double ;
        gpml:y            "65.90775845221802"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idb6b478c0>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:color          "0" ;
        gpml:connectorType  "Elbow" ;
        gpml:graphId        "idb6b478c0" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idb6b478c0/Point/ac156fcf6d52b7a479347e1aefcd5581> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idb6b478c0/Point/a387153ecbb09e1e1be7cebb7e730bb5> ;
        gpml:lineStyle      "Broken" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id3449d8c0>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "id3449d8c0" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id3449d8c0/Point/1797fdd1848738bed129019640e6ae74> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id3449d8c0/Point/43039df2212c681e38f9824d33b2de66> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id7bbfe1e0/Point/c98adf45c138a865ee2126237726ec11>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id7bbfe1e0> ;
        gpml:graphRef     "fefdb" ;
        gpml:relX         "1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "656.8276169761863"^^xsd:double ;
        gpml:y            "357.45736434108517"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id70530ccd/Point/69af5a964a34b796364d4121fc80151e>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id70530ccd> ;
        gpml:graphRef     "e7ea6" ;
        gpml:relX         "0.5"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "747.8255813953488"^^xsd:double ;
        gpml:y            "367.5891472868224"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Label/c422d>
        rdf:type             gpml:Label ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:align           "Center" ;
        gpml:centerX         "189.09712230215825"^^xsd:double ;
        gpml:centerY         "710.6742596810934"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "10.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "c422d" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:href            "" ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "None" ;
        gpml:textlabel       "Elevated glutamate\nlevels" ;
        gpml:valign          "Middle" ;
        gpml:width           "91.0"^^xsd:double ;
        gpml:zorder          "28672"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/bcc7f/Point/5fc3205c503f279d6c0a5a9c028305f2>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/bcc7f> ;
        gpml:graphRef     "f6deb" ;
        gpml:relX         "0.5"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "686.0"^^xsd:double ;
        gpml:y            "1067.0"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972>
        rdfs:seeAlso         <https://www.wikipathways.org/instance/WP2447_r139972> ;
        gpml:author          "[Ariutta, MaintBot, AlexanderPico, Khanspers, Metalmephisto, Susan, Mkutmon, Egonw, DeSl, Fehrhart, Finterly, Eweitz]" ;
        gpml:biopaxRef       "f9c" ;
        gpml:boardHeight     "1262.0"^^xsd:double ;
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        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "id8197ddde" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id8197ddde/Point/677c9a4c3961fd3969415c707128f892> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id8197ddde/Point/b8b6a2bd1a38b234b5d95a49cb6c6182> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idb6b478c0/Point/a387153ecbb09e1e1be7cebb7e730bb5>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idb6b478c0> ;
        gpml:graphRef     "f30d3" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "831.6190476190475"^^xsd:double ;
        gpml:y            "415.357142857143"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Shape/dd030>
        rdf:type             gpml:shape ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:align           "Center" ;
        gpml:centerX         "72.58333333333336"^^xsd:double ;
        gpml:centerY         "980.6640050856442"^^xsd:double ;
        gpml:color           "c0c0c0" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "10.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "dd030" ;
        gpml:height          "154.16666666666674"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "3.0"^^xsd:double ;
        gpml:shape           "0.0"^^xsd:double ;
        gpml:shapeType       "RoundedRectangle" ;
        gpml:textlabel       "Microglial cell" ;
        gpml:valign          "Middle" ;
        gpml:width           "134.83333333333334"^^xsd:double ;
        gpml:zorder          "32770"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Label/b1e57>
        rdf:type             gpml:Label ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:align           "Center" ;
        gpml:centerX         "578.0"^^xsd:double ;
        gpml:centerY         "1133.0"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "10.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "b1e57" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:href            "" ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "None" ;
        gpml:textlabel       "Mitochondria" ;
        gpml:valign          "Middle" ;
        gpml:width           "80.0"^^xsd:double ;
        gpml:zorder          "28672"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/b55cc/Point/15f45605daae18403b3a0172b7721d85>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/b55cc> ;
        gpml:graphRef     "bedbf" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "899.9352126071315"^^xsd:double ;
        gpml:y            "693.5331248778589"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/f6deb>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:align           "Center" ;
        gpml:centerX         "676.0"^^xsd:double ;
        gpml:centerY         "1077.0"^^xsd:double ;
        gpml:color           "ff" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "10.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "f6deb" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "O2-" ;
        gpml:type            "Metabolite" ;
        gpml:valign          "Middle" ;
        gpml:width           "40.0"^^xsd:double ;
        gpml:xrefDataSource  "HMDB" ;
        gpml:xrefId          "HMDB0002168" ;
        gpml:zorder          "32768"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idd75808de>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "idd75808de" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idd75808de/Point/97e28d59512080ae4890e7c7bef1c3eb> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idd75808de/Point/9032752900f9db0f4a74383fa542374e> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id1e1bab7c/Point/abbe7c3cc24704439bd05bc140af6c29>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id1e1bab7c> ;
        gpml:graphRef     "a56bc" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "611.3109038057631"^^xsd:double ;
        gpml:y            "982.5301966731598"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/a173c>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Group/d820d> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:align           "Center" ;
        gpml:centerX         "858.4817275747502"^^xsd:double ;
        gpml:centerY         "164.98338870431908"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "10.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "a173c" ;
        gpml:groupRef        "d8f19" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "PPP3CA" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "80.0"^^xsd:double ;
        gpml:xrefDataSource  "Entrez Gene" ;
        gpml:xrefId          "5530" ;
        gpml:zorder          "32768"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idd31186e6/Point/120b26b3a316b7e288c6f06858769414>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idd31186e6> ;
        gpml:graphRef     "d10b5" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "1164.0000000000018"^^xsd:double ;
        gpml:y            "1077.6666666666665"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idb6d19550/Point/bf59eecfe5956b2eda2b525cb8a05617>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idb6d19550> ;
        gpml:graphRef     "af14a" ;
        gpml:relX         "1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "1130.5224988385423"^^xsd:double ;
        gpml:y            "547.2377785879273"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idfbf571ae>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "idfbf571ae" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idfbf571ae/Point/da00963f7ea35cff0b11f1bd53dbb137> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idfbf571ae/Point/e3ddace8e51c543ec99017404c485ac3> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id6fcdb47/Point/2065203a3334a73c2ebf6cf17e2dc3b4>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id6fcdb47> ;
        gpml:graphRef     "bd217" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "694.5098039215686"^^xsd:double ;
        gpml:y            "992.366163432428"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id9206222b/Point/b620cf0922c5c7c252dc318322069c03>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id9206222b> ;
        gpml:graphRef     "a6f86" ;
        gpml:relX         "1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "1014.0"^^xsd:double ;
        gpml:y            "415.0"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id1de00d7a>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "id1de00d7a" ;
        gpml:hasAnchor      <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id1de00d7a/Anchor/f68e5> ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id1de00d7a/Point/6e0a8d43aa2518213fff16c96db46c6a> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id1de00d7a/Point/53b07c85dfa2d58118444c5b51c8c0d3> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/ida154c80d/Point/195d805478fb4c5a2396ceb99b4fd51c>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/ida154c80d> ;
        gpml:graphRef     "afcbe" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "794.9374999999998"^^xsd:double ;
        gpml:y            "982.366163432428"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/e5005>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:align           "Center" ;
        gpml:centerX         "688.0"^^xsd:double ;
        gpml:centerY         "314.0"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "10.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "e5005" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "BID" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "48.0"^^xsd:double ;
        gpml:xrefDataSource  "Entrez Gene" ;
        gpml:xrefId          "637" ;
        gpml:zorder          "32811"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Label/f875f>
        rdf:type             gpml:Label ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:align           "Center" ;
        gpml:centerX         "1593.3493368014585"^^xsd:double ;
        gpml:centerY         "672.8320943002468"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "10.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "f875f" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:href            "" ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "None" ;
        gpml:textlabel       "Neuron death" ;
        gpml:valign          "Middle" ;
        gpml:width           "80.0"^^xsd:double ;
        gpml:zorder          "32782"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/f9f96/Anchor/a899e>
        rdf:type          gpml:Anchor ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/f9f96> ;
        gpml:graphId      "a899e" ;
        gpml:position     "0.5090559156605083"^^xsd:double ;
        gpml:shape        "None" .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id85aed399/Point/487672593da285da8e7ebc805fa58377>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id85aed399> ;
        gpml:graphRef     "e8673" ;
        gpml:relX         "1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "98.66666666666669"^^xsd:double ;
        gpml:y            "1024.0"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idcbcb0be9/Point/d8d80f5acbf11e6a8ea6d2dbf4a4ee2c>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idcbcb0be9> ;
        gpml:graphRef     "a22a5" ;
        gpml:relX         "1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "1028.0000000000005"^^xsd:double ;
        gpml:y            "871.5398329002153"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id50769619/Point/e050aeb4a24feb91129b2694366e6aee>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id50769619> ;
        gpml:graphRef     "fc1ca" ;
        gpml:relX         "1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "1085.9859292554222"^^xsd:double ;
        gpml:y            "693.5331248778589"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id719c925/Point/ac1ce30a3eae07dc2c991d3c7de4cda7>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id719c925> ;
        gpml:graphRef     "c93d3" ;
        gpml:relX         "1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "175.371335504886"^^xsd:double ;
        gpml:y            "254.42996742671016"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id94a8676c/Point/e582665bef98f5ddb6301df1bc5b900a>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id94a8676c> ;
        gpml:graphRef     "f6282" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "620.0"^^xsd:double ;
        gpml:y            "872.8731662335496"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id1d08513f/Point/33b742720c5400154244ee584fb6edb5>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id1d08513f> ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "1429.3333333333333"^^xsd:double ;
        gpml:y            "874.9160471501232"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idac7d1d20/Point/b931b1f07f47c508ff4dacff8b02b0d3>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idac7d1d20> ;
        gpml:graphRef     "accaa" ;
        gpml:relX         "1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "778.1176470588232"^^xsd:double ;
        gpml:y            "123.20187609927703"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idd37d0e73/Anchor/d6342>
        rdf:type          gpml:Anchor ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idd37d0e73> ;
        gpml:graphId      "d6342" ;
        gpml:position     "0.4"^^xsd:double ;
        gpml:shape        "None" .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idfa0808d1/Point/b63eb8419fffb1fa34e821416f520dba>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idfa0808d1> ;
        gpml:graphRef     "e33d8" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "1048.0"^^xsd:double ;
        gpml:y            "453.0"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id3cd23c9/Point/90add8addc6a74b02c177171977fb09f>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id3cd23c9> ;
        gpml:graphRef     "f04ac" ;
        gpml:relX         "1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "118.0"^^xsd:double ;
        gpml:y            "675.6742596810934"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/a22a5>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:align           "Center" ;
        gpml:centerX         "996.0000000000003"^^xsd:double ;
        gpml:centerY         "871.5398329002153"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "10.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "a22a5" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "p38" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "64.0"^^xsd:double ;
        gpml:xrefDataSource  "Entrez Gene" ;
        gpml:xrefId          "1432" ;
        gpml:zorder          "32768"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id136847e9/Point/783778a72037d897202b7a894636df1>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id136847e9> ;
        gpml:graphRef     "b676b" ;
        gpml:relX         "1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "1031.8221415607982"^^xsd:double ;
        gpml:y            "49.05901895641981"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id709adf57>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "id709adf57" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id709adf57/Point/a1b9962d2ab7d3115240a41a93e44eee> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id709adf57/Point/5999a36205813a6f52935867a22375a4> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id8eb40b49/Point/230f48bd3bc54434fdd6ade86b9587a2>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id8eb40b49> ;
        gpml:graphRef     "d10b5" ;
        gpml:relX         "1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "1234.6666666666683"^^xsd:double ;
        gpml:y            "1077.6666666666665"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id142719ee>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "id142719ee" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id142719ee/Point/1ed081588ff9b56e2381d90acbff3236> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id142719ee/Point/eba1de28f5174788c51a8ec899562bbf> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idbf7b8b9/Point/f512247ccea238e9dde9cac0b131f28e>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idbf7b8b9> ;
        gpml:graphRef     "eb6fd" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "730.0"^^xsd:double ;
        gpml:y            "1077.0"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idb3aea929/Point/ebf9ad7d6116a6a33d8fdfd3e7e36035>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idb3aea929> ;
        gpml:graphRef     "fcde2" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "1039.333333333333"^^xsd:double ;
        gpml:y            "1045.5398329002146"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idcbcb0be9>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "idcbcb0be9" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idcbcb0be9/Point/d8d80f5acbf11e6a8ea6d2dbf4a4ee2c> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idcbcb0be9/Point/5f24139ac797977fa701c963bb38cd71> ;
        gpml:lineStyle      "Broken" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id3cd23c9>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "id3cd23c9" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id3cd23c9/Point/fce0343460a8f27d9aa7232526b25d2e> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id3cd23c9/Point/90add8addc6a74b02c177171977fb09f> ;
        gpml:lineStyle      "Broken" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/c4c17>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:align           "Center" ;
        gpml:centerX         "1078.333333333333"^^xsd:double ;
        gpml:centerY         "1109.3333333333335"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "10.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "c4c17" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "NEFH" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "80.0"^^xsd:double ;
        gpml:xrefDataSource  "Entrez Gene" ;
        gpml:xrefId          "4744" ;
        gpml:zorder          "32768"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/d81a7>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:align           "Center" ;
        gpml:centerX         "861.0"^^xsd:double ;
        gpml:centerY         "1171.0"^^xsd:double ;
        gpml:color           "ff" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "10.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "d81a7" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "H₂O" ;
        gpml:type            "Metabolite" ;
        gpml:valign          "Middle" ;
        gpml:width           "42.0"^^xsd:double ;
        gpml:xrefDataSource  "HMDB" ;
        gpml:xrefId          "HMDB0002111" ;
        gpml:zorder          "32768"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id94a8676c/Point/e5683be5cb31a023a2e43cc0c500ef0d>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id94a8676c> ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "410.6666666666667"^^xsd:double ;
        gpml:y            "934.6666666666666"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/ff83a>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:align           "Center" ;
        gpml:centerX         "421.3095238095238"^^xsd:double ;
        gpml:centerY         "728.357142857143"^^xsd:double ;
        gpml:color           "ff" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "10.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "ff83a" ;
        gpml:height          "29.285714285713993"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "Ca²⁺" ;
        gpml:type            "Metabolite" ;
        gpml:valign          "Middle" ;
        gpml:width           "41.38095238095241"^^xsd:double ;
        gpml:xrefDataSource  "HMDB" ;
        gpml:xrefId          "HMDB0000464" ;
        gpml:zorder          "32768"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/ida7f01dcb/Point/3d7ba9a912ae2f5630210ce51e069e04>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/ida7f01dcb> ;
        gpml:graphRef     "c5456" ;
        gpml:relX         "1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "100.00000000000003"^^xsd:double ;
        gpml:y            "934.8731662335479"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idd46b0994/Point/33871990b37b475c6f81354bdf0d7767>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idd46b0994> ;
        gpml:graphRef     "aa8a3" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "961.2022084903808"^^xsd:double ;
        gpml:y            "728.4911080711361"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idedb1ca54/Point/3dc5b9917a09fe041b6899e1b07a3f8c>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idedb1ca54> ;
        gpml:graphRef     "e257e" ;
        gpml:relX         "1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "1214.208984298831"^^xsd:double ;
        gpml:y            "673.2236057008387"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/InfoBox/cf97358bae30babef312ff945de04838>
        rdf:type          gpml:InfoBox ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:centerX      "0.0"^^xsd:double ;
        gpml:centerY      "0.0"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id117c419f/Anchor/a6f34>
        rdf:type          gpml:Anchor ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id117c419f> ;
        gpml:graphId      "a6f34" ;
        gpml:position     "0.4"^^xsd:double ;
        gpml:shape        "None" .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/ide31a0350/Point/2376692956c202649b6f5c27f8078ff5>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/ide31a0350> ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "1087.1003307607498"^^xsd:double ;
        gpml:y            "491.73098125689086"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idb6b067bd/Point/47892db9c36e660fc38bd4f9bdb1a266>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idb6b067bd> ;
        gpml:graphRef     "f875f" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "1553.3493368014585"^^xsd:double ;
        gpml:y            "672.8320943002468"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idac7d1d20/Point/54aa78206794b3bcbcb7c8e052acf1b0>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idac7d1d20> ;
        gpml:graphRef     "b6e6e" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "819.2184873949584"^^xsd:double ;
        gpml:y            "123.24389290599953"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id8c85cf83/Point/3c1039fd520c5974a082e3f6261e6132>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id8c85cf83> ;
        gpml:graphRef     "e9f96" ;
        gpml:relX         "1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "245.33333333333334"^^xsd:double ;
        gpml:y            "132.33333333333331"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id6fc14d0a>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:color          "999999" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "id6fc14d0a" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id6fc14d0a/Point/ae4b73b61a4b1be506d6f1670c9033d1> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id6fc14d0a/Point/c1fcedeff16048c020bf6dddfa66d0e8> ;
        gpml:lineStyle      "Broken" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Group/d820d>
        rdf:type          gpml:Group ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:graphId      "d820d" ;
        gpml:groupId      "d8f19" ;
        gpml:style        "Complex" .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id8d950ddc/Point/1a912f3fb4b8c26812a91b0ddbb1556b>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id8d950ddc> ;
        gpml:graphRef     "b4635" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "1277.333333333333"^^xsd:double ;
        gpml:y            "1135.9999999999995"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/ida7f01dcb/Point/d48832eea947bb479e6158ed415db27b>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/ida7f01dcb> ;
        gpml:graphRef     "d3da2" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "201.37748344370954"^^xsd:double ;
        gpml:y            "935.8731662335481"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idd37d0e73/Point/5edc9308e651a83869d6b052b2255a0a>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idd37d0e73> ;
        gpml:graphRef     "a6118" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "687.5"^^xsd:double ;
        gpml:y            "1157.0"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id26259e54/Point/45801dddf71b0d51fa0109230d0656cd>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id26259e54> ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "535.0"^^xsd:double ;
        gpml:y            "590.6785714285716"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id69896d2b/Point/593f1b15fd4b1d1801979be75fef2a46>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id69896d2b> ;
        gpml:graphRef     "aeb39" ;
        gpml:relX         "-0.5"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "594.6974789915963"^^xsd:double ;
        gpml:y            "942.8451550290667"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/e9754/Point/1f9fffef059f3f24ac74c01aeb9bbdd2>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/e9754> ;
        gpml:graphRef     "f7616" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "358.0121640307662"^^xsd:double ;
        gpml:y            "739.6582138193121"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Label/bedbf>
        rdf:type             gpml:Label ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:align           "Center" ;
        gpml:centerX         "939.9352126071315"^^xsd:double ;
        gpml:centerY         "693.5331248778589"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "10.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "bedbf" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:href            "" ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "None" ;
        gpml:textlabel       "Accumulation of\nmisfolded proteins" ;
        gpml:valign          "Middle" ;
        gpml:width           "80.0"^^xsd:double ;
        gpml:zorder          "32798"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id70530ccd>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "id70530ccd" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id70530ccd/Point/69af5a964a34b796364d4121fc80151e> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id70530ccd/Point/286bdf29084ea006b9ff877bbbe856f3> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/ida704e090/Point/e3632abba3c3601356cd0eadf5dd4256>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/ida704e090> ;
        gpml:graphRef     "e7ea6" ;
        gpml:relX         "1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "762.1007751937984"^^xsd:double ;
        gpml:y            "357.5891472868224"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/ida3cff5f4/Point/25311b0161f70c572597424120ec6a8b>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/ida3cff5f4> ;
        gpml:graphRef     "f875f" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "1553.3493368014585"^^xsd:double ;
        gpml:y            "672.8320943002468"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id2c89d6cd>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "id2c89d6cd" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id2c89d6cd/Point/4dee1c60801324531078738ca2b1f335> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id2c89d6cd/Point/e152776e0b695612e17e4d3970394af8> ;
        gpml:lineStyle      "Broken" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id6a75a338>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "id6a75a338" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id6a75a338/Point/5400321cc0a77118071bc3d54f1dc570> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id6a75a338/Point/499986f8c27b61f118c7c49a51c75dfe> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/e81dd>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:align           "Center" ;
        gpml:centerX         "1238.666666666667"^^xsd:double ;
        gpml:centerY         "1197.333333333334"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "10.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "e81dd" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "RAC1" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "80.0"^^xsd:double ;
        gpml:xrefDataSource  "Entrez Gene" ;
        gpml:xrefId          "5879" ;
        gpml:zorder          "32768"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idc2e2eee1>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:color          "0" ;
        gpml:connectorType  "Elbow" ;
        gpml:graphId        "idc2e2eee1" ;
        gpml:hasAnchor      <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idc2e2eee1/Anchor/c5b99> ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idc2e2eee1/Point/9f76dbf219d779ee6e963bc9dcea2d88> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idc2e2eee1/Point/b42d27560b00d4e16d80821ccda2e6d2> ;
        gpml:lineStyle      "Broken" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idd37d0e73/Point/a52ba3edd4b491bd12bd7663d00580ae>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idd37d0e73> ;
        gpml:graphRef     "bcd7f" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "731.8333333333329"^^xsd:double ;
        gpml:y            "1089.5398329002144"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/ba994>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:align           "Center" ;
        gpml:centerX         "64.87133550488599"^^xsd:double ;
        gpml:centerY         "254.42996742671014"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "10.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "ba994" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "L-Glutamic acid" ;
        gpml:type            "Metabolite" ;
        gpml:valign          "Middle" ;
        gpml:width           "83.0"^^xsd:double ;
        gpml:xrefDataSource  "HMDB" ;
        gpml:xrefId          "HMDB0000148" ;
        gpml:zorder          "32778"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/ida0c052ab/Point/51e8d45e729750a54d0c832a181c27d1>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/ida0c052ab> ;
        gpml:graphRef     "c9a4d" ;
        gpml:relX         "1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "959.3666061705987"^^xsd:double ;
        gpml:y            "357.18586574460085"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id9999669c/Point/86fe90a2db0ac9ab1875e2e04230639a>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id9999669c> ;
        gpml:graphRef     "a20e1" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "1196.5226860254083"^^xsd:double ;
        gpml:y            "65.50451911655637"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id8eb40b49/Point/eeb1e2e4a33f742f4528a8868b2718d4>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id8eb40b49> ;
        gpml:graphRef     "e38ad" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "1302.3333333333344"^^xsd:double ;
        gpml:y            "1076.9999999999995"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id6a78f165/Point/f93ed51351ee80ec16a3d974169d2f7a>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id6a78f165> ;
        gpml:graphRef     "af14a" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "1029.0687173259378"^^xsd:double ;
        gpml:y            "547.2377785879273"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id5d12dff3>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "id5d12dff3" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id5d12dff3/Point/f596ddbca609bd72774029fbf718a5d> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id5d12dff3/Point/dffaf95d6d30f8732a052d2c0e548d25> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Shape/dee35>
        rdf:type             gpml:shape ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:align           "Center" ;
        gpml:centerX         "82.20466883821932"^^xsd:double ;
        gpml:centerY         "201.9519543973942"^^xsd:double ;
        gpml:color           "c0c0c0" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "10.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "dee35" ;
        gpml:height          "194.5"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "3.0"^^xsd:double ;
        gpml:shape           "0.0"^^xsd:double ;
        gpml:shapeType       "RoundedRectangle" ;
        gpml:textlabel       "Astrocyte" ;
        gpml:valign          "Middle" ;
        gpml:width           "145.0"^^xsd:double ;
        gpml:zorder          "16384"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/a5d0f/Point/496c9a70aa63863d18ca0f8560f6d4c0>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/a5d0f> ;
        gpml:graphRef     "bedbf" ;
        gpml:relX         "1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "979.9352126071315"^^xsd:double ;
        gpml:y            "693.5331248778589"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idfe11c8d2/Point/17e9fbe641e6afdb68ace0c5af8a0c10>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idfe11c8d2> ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "618.8165304268846"^^xsd:double ;
        gpml:y            "921.9082652134423"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Label/bfb26>
        rdf:type             gpml:Label ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:align           "Center" ;
        gpml:centerX         "1098.0"^^xsd:double ;
        gpml:centerY         "196.0"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "10.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "bfb26" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:href            "" ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "None" ;
        gpml:textlabel       "Increased\nexpression" ;
        gpml:valign          "Middle" ;
        gpml:width           "64.0"^^xsd:double ;
        gpml:zorder          "28672"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idb3584e45/Point/153b46cf919ab9f627c0e042cefb44dc>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idb3584e45> ;
        gpml:graphRef     "bafb8" ;
        gpml:relX         "1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "105.33333333333333"^^xsd:double ;
        gpml:y            "132.3333333333332"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Group/b3274>
        rdf:type          gpml:Group ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:graphId      "b3274" ;
        gpml:groupId      "faf2f" ;
        gpml:style        "Complex" .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id8c85cf83/Point/a4932eef234f07c48af8f9d42be11cca>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id8c85cf83> ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "627.0"^^xsd:double ;
        gpml:y            "1052.0"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id751c8da1>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "id751c8da1" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id751c8da1/Point/ee3a4787fb41c028923469f78cae30fe> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id751c8da1/Point/82353ab490b96b17ee850f378acca0a1> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idde65c6be/Point/87821fc2bd403598cbfc22aedbf20429>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idde65c6be> ;
        gpml:graphRef     "ba994" ;
        gpml:relX         "1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "106.37133550488599"^^xsd:double ;
        gpml:y            "254.42996742671016"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idb6d19550/Point/a9ae11b97d40ed5e22759c23f4edcfab>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idb6d19550> ;
        gpml:graphRef     "f875f" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "1553.3493368014585"^^xsd:double ;
        gpml:y            "672.8320943002468"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idde65c6be/Point/a4a83253d95d2e864f12a05d9d5b8152>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idde65c6be> ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "228.0"^^xsd:double ;
        gpml:y            "254.0"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/dae76>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:align           "Center" ;
        gpml:centerX         "804.5"^^xsd:double ;
        gpml:centerY         "1147.0"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "10.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "dae76" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "CAT" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "41.0"^^xsd:double ;
        gpml:xrefDataSource  "Entrez Gene" ;
        gpml:xrefId          "847" ;
        gpml:zorder          "32768"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id8c85cf83>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:color          "0" ;
        gpml:connectorType  "Segmented" ;
        gpml:graphId        "id8c85cf83" ;
        gpml:hasComment     <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Comment/6df8a1bb053cb4570a8bc4deaacc3efa> ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id8c85cf83/Point/7bef0423abf60d65ebf7b3ab70991167> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id8c85cf83/Point/e01f63bffd78916a6c8ab5673a25e7b6> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id8c85cf83/Point/a4932eef234f07c48af8f9d42be11cca> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id8c85cf83/Point/3c1039fd520c5974a082e3f6261e6132> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id8c85cf83/Point/1cf0e9576430fb133774a1c33575211a> ;
        gpml:lineStyle      "Broken" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id19a072ea/Point/4b012fe529871b137b78b4e829fefa60>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id19a072ea> ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "1420.0"^^xsd:double ;
        gpml:y            "544.1660471501234"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/iddfc4ddf2/Point/b71880e08b46959fa7d93bd6c22a41dc>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/iddfc4ddf2> ;
        gpml:graphRef     "d6fe8" ;
        gpml:relX         "0.5"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "904.5970961887508"^^xsd:double ;
        gpml:y            "245.0"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idb6b067bd>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:color          "0" ;
        gpml:connectorType  "Elbow" ;
        gpml:graphId        "idb6b067bd" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idb6b067bd/Point/8bda44147427c4acbfe262f05295494> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idb6b067bd/Point/8ca3ff53bd86da17111fc88ef0ec3507> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idb6b067bd/Point/47892db9c36e660fc38bd4f9bdb1a266> ;
        gpml:lineStyle      "Broken" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/ida1e5ab90>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "ida1e5ab90" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/ida1e5ab90/Point/b32473ce3a15e4b373abaf33051c2f17> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/ida1e5ab90/Point/5297978759bbe30b2b9df7a0030a0524> ;
        gpml:lineStyle      "Broken" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idbf7b8b9/Point/8aede580e571abbe2daeffe3b52bc571>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idbf7b8b9> ;
        gpml:graphRef     "bcd7f" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "731.8333333333329"^^xsd:double ;
        gpml:y            "1069.5398329002144"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/e8673>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:align           "Center" ;
        gpml:centerX         "68.33333333333314"^^xsd:double ;
        gpml:centerY         "1024.0"^^xsd:double ;
        gpml:color           "ff" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "10.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "e8673" ;
        gpml:height          "20.000000000000007"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "NO" ;
        gpml:type            "Metabolite" ;
        gpml:valign          "Middle" ;
        gpml:width           "60.66666666666708"^^xsd:double ;
        gpml:xrefDataSource  "HMDB" ;
        gpml:xrefId          "HMDB0003378" ;
        gpml:zorder          "32826"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id136847e9>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:color          "0" ;
        gpml:connectorType  "Elbow" ;
        gpml:graphId        "id136847e9" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id136847e9/Point/9fed4b1e4289be5117c53410e09994ae> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id136847e9/Point/dbacad9973d2d7a478ce53e4da48ffaa> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id136847e9/Point/783778a72037d897202b7a894636df1> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id751c8da1/Point/82353ab490b96b17ee850f378acca0a1>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id751c8da1> ;
        gpml:graphRef     "fefdb" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "625.6657464725891"^^xsd:double ;
        gpml:y            "367.45736434108517"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Label/e7ea6>
        rdf:type             gpml:Label ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:align           "Center" ;
        gpml:centerX         "733.5503875968992"^^xsd:double ;
        gpml:centerY         "357.5891472868224"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "10.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "e7ea6" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:href            "" ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "None" ;
        gpml:textlabel       "Aggregates" ;
        gpml:valign          "Middle" ;
        gpml:width           "57.10077519379843"^^xsd:double ;
        gpml:zorder          "28672"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id9206222b/Point/337d092ad2f6d7d22089aaa2c12f3249>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id9206222b> ;
        gpml:graphRef     "f7b4d" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "1037.0"^^xsd:double ;
        gpml:y            "415.5"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idbf7b8b9>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "idbf7b8b9" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idbf7b8b9/Point/8aede580e571abbe2daeffe3b52bc571> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idbf7b8b9/Point/f512247ccea238e9dde9cac0b131f28e> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/ide9959d31>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:color          "0" ;
        gpml:connectorType  "Elbow" ;
        gpml:graphId        "ide9959d31" ;
        gpml:hasAnchor      <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/ide9959d31/Anchor/faca6> ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/ide9959d31/Point/43eb1fe50c4830ea630ae8f0c8170084> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/ide9959d31/Point/7c55d2922b1a9f2e6489b767aad604d6> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id3449d8c0/Point/1797fdd1848738bed129019640e6ae74>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id3449d8c0> ;
        gpml:graphRef     "a0d6a" ;
        gpml:relX         "-0.5"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "1129.647005444646"^^xsd:double ;
        gpml:y            "226.99563865558025"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idcbcb0be9/Point/5f24139ac797977fa701c963bb38cd71>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idcbcb0be9> ;
        gpml:graphRef     "dfe3d" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "1273.3514986376022"^^xsd:double ;
        gpml:y            "871.0263396911889"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id8197ddde/Point/677c9a4c3961fd3969415c707128f892>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id8197ddde> ;
        gpml:graphRef     "fefdb" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "594.503875968992"^^xsd:double ;
        gpml:y            "357.45736434108517"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id6fcdb47>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:color          "0" ;
        gpml:connectorType  "Segmented" ;
        gpml:graphId        "id6fcdb47" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id6fcdb47/Point/ca18f2d1a545f5c18bf17fbd4c012009> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id6fcdb47/Point/2065203a3334a73c2ebf6cf17e2dc3b4> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id6fcdb47/Point/9f8907a1555355b335444189567271b2> ;
        gpml:lineStyle      "Broken" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idfa0808d1/Point/b7d647cb0653648e878572c4629797a0>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idfa0808d1> ;
        gpml:graphRef     "aa8a3" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "982.8061759100196"^^xsd:double ;
        gpml:y            "718.4911080711361"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idd31186e6>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "idd31186e6" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idd31186e6/Point/120b26b3a316b7e288c6f06858769414> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idd31186e6/Point/d19a93ec7d3c4d913c73e2957db65807> ;
        gpml:lineStyle      "Broken" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/iddfc4ddf2/Point/fd0d9312a9d5e5bf203a70c04fd8e06e>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/iddfc4ddf2> ;
        gpml:graphRef     "c5b99" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "1003.2377495462794"^^xsd:double ;
        gpml:y            "185.41095718323533"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idd6d367a2>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "idd6d367a2" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idd6d367a2/Point/eb616685ae4f57f716983ab20e47477d> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idd6d367a2/Point/5ec1b9e00c629230fd4baa06ee60134> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/f9f96>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "f9f96" ;
        gpml:hasAnchor      <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/f9f96/Anchor/a899e> ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/f9f96/Point/dd8334cd1d031af5353fe7f83a97b48> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/f9f96/Point/a3e7d22053fc17c85aa7b2bc9ccbdfcd> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "32791"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Label/df927>
        rdf:type             gpml:Label ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:align           "Center" ;
        gpml:centerX         "942.0"^^xsd:double ;
        gpml:centerY         "195.0"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "10.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "df927" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:href            "" ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "None" ;
        gpml:textlabel       "Reduced\nexpression" ;
        gpml:valign          "Middle" ;
        gpml:width           "80.0"^^xsd:double ;
        gpml:zorder          "28672"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/a5d0f/Point/e8a9dae9e93e9bfa9b877cc98f1c63a7>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/a5d0f> ;
        gpml:graphRef     "fc1ca" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "1025.1007751937984"^^xsd:double ;
        gpml:y            "693.5331248778589"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idb3584e45/Point/f2f2bb41b7931e514f432fde09f78ae4>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idb3584e45> ;
        gpml:graphRef     "e9f96" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "182.33333333333334"^^xsd:double ;
        gpml:y            "132.33333333333331"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id719c925>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "id719c925" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id719c925/Point/a1ad7ebbf25b42c2f87ed84cc9c8b137> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id719c925/Point/ac1ce30a3eae07dc2c991d3c7de4cda7> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/ef623>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:align           "Center" ;
        gpml:centerX         "659.5"^^xsd:double ;
        gpml:centerY         "1119.0"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "10.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "ef623" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "CCS" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "45.0"^^xsd:double ;
        gpml:xrefDataSource  "Entrez Gene" ;
        gpml:xrefId          "9973" ;
        gpml:zorder          "32768"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id1d08513f/Point/ddd54ef53264bf3c6e316d8841b75e68>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id1d08513f> ;
        gpml:graphRef     "e38ad" ;
        gpml:relX         "1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "1395.6666666666665"^^xsd:double ;
        gpml:y            "1076.9999999999995"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/bdd14>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:align           "Center" ;
        gpml:centerX         "794.5503875968992"^^xsd:double ;
        gpml:centerY         "391.5891472868225"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "10.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "bdd14" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "TOM40" ;
        gpml:type            "Protein" ;
        gpml:valign          "Middle" ;
        gpml:width           "56.89922480620157"^^xsd:double ;
        gpml:xrefDataSource  "UniProtKB" ;
        gpml:xrefId          "O96008" ;
        gpml:zorder          "32813"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id7c9c96e3/Point/76adf11deb402d2b365b05dcd0ab2dcd>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id7c9c96e3> ;
        gpml:graphRef     "a0090" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "781.0"^^xsd:double ;
        gpml:y            "1077.0"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idb6d19550/Point/9a0cbd85ba7a8a742203b240e4bd0ce2>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idb6d19550> ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "1384.0"^^xsd:double ;
        gpml:y            "610.0349364440871"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id9c0ea925/Point/4b1eb853cb63ac2f8dcb5cd4cbae7a73>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id9c0ea925> ;
        gpml:graphRef     "fefdb" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "625.6657464725891"^^xsd:double ;
        gpml:y            "347.45736434108517"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Shape/cb3d3>
        rdf:type             gpml:shape ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:align           "Center" ;
        gpml:centerX         "1065.6007751937987"^^xsd:double ;
        gpml:centerY         "358.089147286822"^^xsd:double ;
        gpml:color           "c0c0c0" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "10.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "cb3d3" ;
        gpml:height          "253.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "3.0"^^xsd:double ;
        gpml:shape           "0.0"^^xsd:double ;
        gpml:shapeType       "Mitochondria" ;
        gpml:textlabel       "Mitochondria" ;
        gpml:valign          "Middle" ;
        gpml:width           "589.0"^^xsd:double ;
        gpml:zorder          "-2"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idedb1ca54>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "idedb1ca54" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idedb1ca54/Point/9f1c3cdf618004363052a0914dd207d> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idedb1ca54/Point/3dc5b9917a09fe041b6899e1b07a3f8c> ;
        gpml:lineStyle      "Broken" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id70530ccd/Point/286bdf29084ea006b9ff877bbbe856f3>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id70530ccd> ;
        gpml:graphRef     "bdd14" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "794.5503875968992"^^xsd:double ;
        gpml:y            "381.5891472868225"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id58649f3e/Point/17ece6d7131461bf9a8c714950f48eed>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id58649f3e> ;
        gpml:graphRef     "b4635" ;
        gpml:relX         "1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "1357.333333333333"^^xsd:double ;
        gpml:y            "1135.9999999999995"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/c1091>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Group/b3274> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:align           "Center" ;
        gpml:centerX         "876.416666666667"^^xsd:double ;
        gpml:centerY         "884.6231662335485"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "10.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "c1091" ;
        gpml:groupRef        "faf2f" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "MKK6" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "80.0"^^xsd:double ;
        gpml:xrefDataSource  "Entrez Gene" ;
        gpml:xrefId          "5608" ;
        gpml:zorder          "32768"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idd31186e6/Point/d19a93ec7d3c4d913c73e2957db65807>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idd31186e6> ;
        gpml:graphRef     "d4a30" ;
        gpml:relX         "1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "1119.333333333333"^^xsd:double ;
        gpml:y            "1077.8731662335485"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/ida90aa669>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:color          "0" ;
        gpml:connectorType  "Elbow" ;
        gpml:graphId        "ida90aa669" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/ida90aa669/Point/968757e91fbdf8af9d64ef142ed2c59a> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/ida90aa669/Point/23550e233687febef3401dbb49304b7d> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id3449d8c0/Point/43039df2212c681e38f9824d33b2de66>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id3449d8c0> ;
        gpml:graphRef     "c5b99" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "1003.2377495462794"^^xsd:double ;
        gpml:y            "185.41095718323533"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id26259e54/Point/2ff6cb254f4d58bfa646637b27304bf2>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id26259e54> ;
        gpml:graphRef     "e33d8" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "1048.0"^^xsd:double ;
        gpml:y            "453.0"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/f4cf0>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:align           "Center" ;
        gpml:centerX         "884.5"^^xsd:double ;
        gpml:centerY         "1116.5"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "10.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "f4cf0" ;
        gpml:height          "19.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "GPX1" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "39.0"^^xsd:double ;
        gpml:xrefDataSource  "Entrez Gene" ;
        gpml:xrefId          "2876" ;
        gpml:zorder          "32768"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id28b00f54>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "id28b00f54" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id28b00f54/Point/393822f214e75c940a2a7e283a764efa> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id28b00f54/Point/4d9a6f5daea78e32ec265e9a3dcae7a8> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/bb36d>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:align           "Center" ;
        gpml:centerX         "240.4591611479026"^^xsd:double ;
        gpml:centerY         "1024.5398329002146"^^xsd:double ;
        gpml:color           "ff" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "10.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "bb36d" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "NO" ;
        gpml:type            "Metabolite" ;
        gpml:valign          "Middle" ;
        gpml:width           "64.0000000000007"^^xsd:double ;
        gpml:xrefDataSource  "HMDB" ;
        gpml:xrefId          "HMDB0003378" ;
        gpml:zorder          "32827"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Label/bbab8>
        rdf:type             gpml:Label ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Group/e7d4a> ;
        gpml:align           "Center" ;
        gpml:centerX         "1826.5"^^xsd:double ;
        gpml:centerY         "99.0"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Bold" ;
        gpml:graphId         "bbab8" ;
        gpml:groupRef        "e7d4a" ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:href            "" ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "None" ;
        gpml:textlabel       "Activating mutation" ;
        gpml:valign          "Middle" ;
        gpml:width           "145.0"^^xsd:double ;
        gpml:zorder          "28672"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id1e1bab7c>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "id1e1bab7c" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id1e1bab7c/Point/51d28491277458fbe1fa2043d5db3d45> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id1e1bab7c/Point/abbe7c3cc24704439bd05bc140af6c29> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/d1b7a>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:align           "Center" ;
        gpml:centerX         "1192.0"^^xsd:double ;
        gpml:centerY         "1135.9999999999995"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "10.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "d1b7a" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "ALS2" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "80.0"^^xsd:double ;
        gpml:xrefDataSource  "Entrez Gene" ;
        gpml:xrefId          "57679" ;
        gpml:zorder          "32768"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/aeb39>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:align           "Center" ;
        gpml:centerX         "611.0308123249298"^^xsd:double ;
        gpml:centerY         "952.8451550290667"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "10.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "aeb39" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "NOS1" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "65.33333333333343"^^xsd:double ;
        gpml:xrefDataSource  "Entrez Gene" ;
        gpml:xrefId          "4842" ;
        gpml:zorder          "32768"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/fbdfc>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:align           "Center" ;
        gpml:centerX         "750.6666666666655"^^xsd:double ;
        gpml:centerY         "872.5398329002154"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "10.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "fbdfc" ;
        gpml:height          "21.99999999999974"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "ASK1" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "63.99999999999989"^^xsd:double ;
        gpml:xrefDataSource  "Entrez Gene" ;
        gpml:xrefId          "4217" ;
        gpml:zorder          "32768"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/ida7f01dcb>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "ida7f01dcb" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/ida7f01dcb/Point/3d7ba9a912ae2f5630210ce51e069e04> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/ida7f01dcb/Point/d48832eea947bb479e6158ed415db27b> ;
        gpml:lineStyle      "Broken" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/b4635>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:align           "Center" ;
        gpml:centerX         "1317.333333333333"^^xsd:double ;
        gpml:centerY         "1135.9999999999995"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "10.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "b4635" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "RAB5A" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "80.0"^^xsd:double ;
        gpml:xrefDataSource  "Entrez Gene" ;
        gpml:xrefId          "5868" ;
        gpml:zorder          "32768"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/abf1b>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:align           "Center" ;
        gpml:centerX         "1127.0"^^xsd:double ;
        gpml:centerY         "96.0"^^xsd:double ;
        gpml:color           "14961e" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Bold" ;
        gpml:graphId         "abf1b" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "RoundedRectangle" ;
        gpml:textlabel       "Apoptosis" ;
        gpml:type            "Pathway" ;
        gpml:valign          "Middle" ;
        gpml:width           "80.0"^^xsd:double ;
        gpml:xrefDataSource  "WikiPathways" ;
        gpml:xrefId          "WP254" ;
        gpml:zorder          "32768"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idb6b478c0/Point/ac156fcf6d52b7a479347e1aefcd5581>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idb6b478c0> ;
        gpml:graphRef     "ff83a" ;
        gpml:relX         "1.0"^^xsd:double ;
        gpml:relY         "-0.5"^^xsd:double ;
        gpml:x            "442.0"^^xsd:double ;
        gpml:y            "721.0357142857144"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/State/f443a>
        rdf:type            gpml:State ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        gpml:color          "0" ;
        gpml:fillColor      "ffffff" ;
        gpml:graphId        "f443a" ;
        gpml:graphRef       "a14b7" ;
        gpml:height         "15.0"^^xsd:double ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:relX           "-0.9403558034839425"^^xsd:double ;
        gpml:relY           "-0.550387596899202"^^xsd:double ;
        gpml:shapeType      "Triangle" ;
        gpml:stateOf        <http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/a14b7> ;
        gpml:stateType      "Unknown" ;
        gpml:textlabel      "" ;
        gpml:width          "15.0"^^xsd:double ;
        gpml:zorder         "32829"^^xsd:long .
