@prefix biopax:  <http://www.biopax.org/release/biopax-level3.owl#> .
@prefix cito:    <http://purl.org/spar/cito/> .
@prefix dc:      <http://purl.org/dc/elements/1.1/> .
@prefix dcterms: <http://purl.org/dc/terms/> .
@prefix foaf:    <http://xmlns.com/foaf/0.1/> .
@prefix freq:    <http://purl.org/cld/freq/> .
@prefix gpml:    <http://vocabularies.wikipathways.org/gpml#> .
@prefix obo:     <http://purl.obolibrary.org/obo/> .
@prefix owl:     <http://www.w3.org/2002/07/owl#> .
@prefix pav:     <http://purl.org/pav/> .
@prefix prov:    <http://www.w3.org/ns/prov#> .
@prefix rdf:     <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix rdfs:    <http://www.w3.org/2000/01/rdf-schema#> .
@prefix skos:    <http://www.w3.org/2004/02/skos/core#> .
@prefix void:    <http://rdfs.org/ns/void#> .
@prefix wp:      <http://vocabularies.wikipathways.org/wp#> .
@prefix wprdf:   <http://rdf.wikipathways.org/> .
@prefix xsd:     <http://www.w3.org/2001/XMLSchema#> .

<http://rdf.wikipathways.org/Pathway/WP5545_r139134/DataNode/fa1e0>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5545_r139134> , <http://rdf.wikipathways.org/Pathway/WP5545_r139134/Group/b7d63> ;
        gpml:align           "Center" ;
        gpml:centerX         "322.33810359569657"^^xsd:double ;
        gpml:centerY         "155.5404234732913"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "fa1e0" ;
        gpml:groupRef        "e4e6b" ;
        gpml:hasComment      <http://rdf.wikipathways.org/Pathway/WP5545_r139134/Comment/861774c6170ceeb9b6499ae4432b1512> ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "MAPK10" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "90.0"^^xsd:double ;
        gpml:xrefDataSource  "Entrez Gene" ;
        gpml:xrefId          "5602" ;
        gpml:zorder          "33014"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5545_r139134/Interaction/id1ec4c874/Point/920abad66537b828af6f0599314551bf>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5545_r139134> , <http://rdf.wikipathways.org/Pathway/WP5545_r139134/Interaction/id1ec4c874> ;
        gpml:graphRef     "e448a" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "573.8569371315389"^^xsd:double ;
        gpml:y            "240.3311057108142"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5545_r139134/DataNode/e448a>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5545_r139134> ;
        gpml:align           "Center" ;
        gpml:centerX         "573.8569371315389"^^xsd:double ;
        gpml:centerY         "252.8311057108142"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "e448a" ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "SIS3" ;
        gpml:type            "Protein" ;
        gpml:valign          "Middle" ;
        gpml:width           "90.0"^^xsd:double ;
        gpml:xrefDataSource  "UniProtKB" ;
        gpml:xrefId          "Q8GYT9" ;
        gpml:zorder          "32768"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5545_r139134/Interaction/id782dadbb>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP5545_r139134> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "id782dadbb" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP5545_r139134/Interaction/id782dadbb/Point/f99e799cfdf214acd8e9e3d2ee03478e> , <http://rdf.wikipathways.org/Pathway/WP5545_r139134/Interaction/id782dadbb/Point/97b6d8f4be3056556197fb5410447e25> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5545_r139134/Interaction/id11bd7f2/Point/89308f98e2e353dc317f20fa3f666e5e>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5545_r139134> , <http://rdf.wikipathways.org/Pathway/WP5545_r139134/Interaction/id11bd7f2> ;
        gpml:graphRef     "d0135" ;
        gpml:relX         "1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "212.5925925925925"^^xsd:double ;
        gpml:y            "188.4325637910086"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5545_r139134/Interaction/a9943/Point/ddd54ef53264bf3c6e316d8841b75e68>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5545_r139134> , <http://rdf.wikipathways.org/Pathway/WP5545_r139134/Interaction/a9943> ;
        gpml:graphRef     "c5db2" ;
        gpml:relX         "1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "212.59259259259255"^^xsd:double ;
        gpml:y            "59.58333333333336"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5545_r139134/DataNode/d2707>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5545_r139134> ;
        gpml:align           "Center" ;
        gpml:centerX         "169.2618469015784"^^xsd:double ;
        gpml:centerY         "501.9198055893071"^^xsd:double ;
        gpml:color           "ff" ;
        gpml:fillColor       "ffdddd" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "d2707" ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "RoundedRectangle" ;
        gpml:textlabel       "Intraocular pressure" ;
        gpml:type            "Unknown" ;
        gpml:valign          "Middle" ;
        gpml:width           "179.87241798298905"^^xsd:double ;
        gpml:xrefDataSource  "Wikidata" ;
        gpml:xrefId          "Q650050" ;
        gpml:zorder          "32768"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5545_r139134/Comment/7c00665e76366f3804af027b5bf81715>
        rdf:type          gpml:Comment ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5545_r139134/DataNode/bce60> ;
        gpml:commentText  "\"Fibronectin exists as a protein dimer, consisting of two nearly identical monomers linked by a pair of disulfide bonds.\" Source: Wikipedia, https://en.wikipedia.org/wiki/Fibronectin" .

<http://rdf.wikipathways.org/Pathway/WP5545_r139134/Interaction/d313f/Point/66c40335250bcbb840a6735c5ac5bc63>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5545_r139134> , <http://rdf.wikipathways.org/Pathway/WP5545_r139134/Interaction/d313f> ;
        gpml:graphRef     "c5732" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "169.28221052157795"^^xsd:double ;
        gpml:y            "451.52645020476086"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5545_r139134/DataNode/bce60>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5545_r139134> , <http://rdf.wikipathways.org/Pathway/WP5545_r139134/Group/c5732> ;
        gpml:align           "Center" ;
        gpml:centerX         "124.2822105215779"^^xsd:double ;
        gpml:centerY         "431.02645020476086"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "bce60" ;
        gpml:groupRef        "d8621" ;
        gpml:hasComment      <http://rdf.wikipathways.org/Pathway/WP5545_r139134/Comment/7c00665e76366f3804af027b5bf81715> , <http://rdf.wikipathways.org/Pathway/WP5545_r139134/Comment/86a3314cf47e356964305d297522e5b9> ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "FN1" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "90.0"^^xsd:double ;
        gpml:xrefDataSource  "Entrez Gene" ;
        gpml:xrefId          "2335" ;
        gpml:zorder          "32768"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5545_r139134/Interaction/fba40>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP5545_r139134> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "fba40" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP5545_r139134/Interaction/fba40/Point/abbe7c3cc24704439bd05bc140af6c29> , <http://rdf.wikipathways.org/Pathway/WP5545_r139134/Interaction/fba40/Point/51d28491277458fbe1fa2043d5db3d45> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "33027"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5545_r139134/Interaction/idc2941205>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP5545_r139134> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "idc2941205" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP5545_r139134/Interaction/idc2941205/Point/8f366908d858f6ea146c643ebfcf4f3> , <http://rdf.wikipathways.org/Pathway/WP5545_r139134/Interaction/idc2941205/Point/e59e89ca1c259172ecbf48949b0f6591> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5545_r139134/Interaction/dc49e>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP5545_r139134> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "dc49e" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP5545_r139134/Interaction/dc49e/Point/6e0a8d43aa2518213fff16c96db46c6a> , <http://rdf.wikipathways.org/Pathway/WP5545_r139134/Interaction/dc49e/Point/53b07c85dfa2d58118444c5b51c8c0d3> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "33026"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5545_r139134/Interaction/idc2941205/Point/8f366908d858f6ea146c643ebfcf4f3>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5545_r139134> , <http://rdf.wikipathways.org/Pathway/WP5545_r139134/Interaction/idc2941205> ;
        gpml:graphRef     "bf517" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "167.59259259259255"^^xsd:double ;
        gpml:y            "253.16513658251023"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5545_r139134/Interaction/id1ec4c874/Point/aabf1bd82f6fbcfc34450c84a8a953ad>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5545_r139134> , <http://rdf.wikipathways.org/Pathway/WP5545_r139134/Interaction/id1ec4c874> ;
        gpml:graphRef     "cdeea" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "573.8569371315389"^^xsd:double ;
        gpml:y            "200.9325637910086"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5545_r139134/Comment/ad09e29d00812340c68a18df73f15ad9>
        rdf:type          gpml:Comment ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5545_r139134/DataNode/d7a95> ;
        gpml:commentText  "OCR lexicon match: TGF-B1" .

<http://rdf.wikipathways.org/Pathway/WP5545_r139134/Interaction/a9943>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP5545_r139134> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "a9943" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP5545_r139134/Interaction/a9943/Point/e93c6510633a9fecde87080ef20ec4c2> , <http://rdf.wikipathways.org/Pathway/WP5545_r139134/Interaction/a9943/Point/ddd54ef53264bf3c6e316d8841b75e68> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "33025"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5545_r139134/Interaction/id782dadbb/Point/f99e799cfdf214acd8e9e3d2ee03478e>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5545_r139134> , <http://rdf.wikipathways.org/Pathway/WP5545_r139134/Interaction/id782dadbb> ;
        gpml:graphRef     "e25da" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "59.15069078799306"^^xsd:double ;
        gpml:y            "111.55050402772142"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5545_r139134/Comment/861774c6170ceeb9b6499ae4432b1512>
        rdf:type          gpml:Comment ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5545_r139134/DataNode/fa1e0> , <http://rdf.wikipathways.org/Pathway/WP5545_r139134/DataNode/c9771> , <http://rdf.wikipathways.org/Pathway/WP5545_r139134/DataNode/c8496> ;
        gpml:commentText  "OCR lexicon match: JNK" .

<http://rdf.wikipathways.org/Pathway/WP5545_r139134/DataNode/aaf88>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5545_r139134> ;
        gpml:align           "Center" ;
        gpml:centerX         "573.8569371315389"^^xsd:double ;
        gpml:centerY         "70.33386211241604"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "aaf88" ;
        gpml:hasComment      <http://rdf.wikipathways.org/Pathway/WP5545_r139134/Comment/f357630c646d9824aaec4961c1894c92> ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "TGFB2" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "90.0"^^xsd:double ;
        gpml:xrefDataSource  "Entrez Gene" ;
        gpml:xrefId          "7042" ;
        gpml:zorder          "33019"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5545_r139134/Comment/196b0887c11f5262736a2b6cf84962c>
        rdf:type          gpml:Comment ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5545_r139134/DataNode/e42a5> ;
        gpml:commentText  "\"α-SMA\" originally" .

<http://rdf.wikipathways.org/Pathway/WP5545_r139134/DataNode/cdeea>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5545_r139134> ;
        gpml:align           "Center" ;
        gpml:centerX         "573.8569371315389"^^xsd:double ;
        gpml:centerY         "188.4325637910086"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "cdeea" ;
        gpml:hasComment      <http://rdf.wikipathways.org/Pathway/WP5545_r139134/Comment/87bee201aa936431d0eeca2287915125> ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "SMAD3" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "90.0"^^xsd:double ;
        gpml:xrefDataSource  "Entrez Gene" ;
        gpml:xrefId          "4088" ;
        gpml:zorder          "33020"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5545_r139134/Interaction/d313f/Point/2ff6cb254f4d58bfa646637b27304bf2>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5545_r139134> , <http://rdf.wikipathways.org/Pathway/WP5545_r139134/Interaction/d313f> ;
        gpml:graphRef     "d2707" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "169.2618469015784"^^xsd:double ;
        gpml:y            "489.4198055893071"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5545_r139134/Interaction/id34f04aed/Point/da6960ae29fc27bd06a0cf118544687c>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5545_r139134> , <http://rdf.wikipathways.org/Pathway/WP5545_r139134/Interaction/id34f04aed> ;
        gpml:graphRef     "c5732" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "169.28221052157795"^^xsd:double ;
        gpml:y            "385.52645020476086"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5545_r139134/Interaction/fba40/Point/51d28491277458fbe1fa2043d5db3d45>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5545_r139134> , <http://rdf.wikipathways.org/Pathway/WP5545_r139134/Interaction/fba40> ;
        gpml:graphRef     "aaf88" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "573.8569371315389"^^xsd:double ;
        gpml:y            "82.83386211241604"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5545_r139134/Comment/b88d5b74e099ea2e669b0069eaf163bb>
        rdf:type          gpml:Comment ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5545_r139134/DataNode/c5db2> ;
        gpml:commentText  "OCR lexicon match: TGF-B3" .

<http://rdf.wikipathways.org/Pathway/WP5545_r139134>
        rdfs:seeAlso         <https://www.wikipathways.org/instance/WP5545_r139134> ;
        gpml:author          "[DeSl, Egonw, Eweitz]" ;
        gpml:biopaxRef       "c76" ;
        gpml:boardHeight     "544.4198055893071"^^xsd:double ;
        gpml:boardWidth      "648.8569371315389"^^xsd:double ;
        gpml:data-Source     "WikiPathways" ;
        gpml:hasDataNode     <http://rdf.wikipathways.org/Pathway/WP5545_r139134/DataNode/d7a95> , <http://rdf.wikipathways.org/Pathway/WP5545_r139134/DataNode/e25da> , <http://rdf.wikipathways.org/Pathway/WP5545_r139134/DataNode/c9771> , <http://rdf.wikipathways.org/Pathway/WP5545_r139134/DataNode/fa1e0> , <http://rdf.wikipathways.org/Pathway/WP5545_r139134/DataNode/cdeea> , <http://rdf.wikipathways.org/Pathway/WP5545_r139134/DataNode/bf517> , <http://rdf.wikipathways.org/Pathway/WP5545_r139134/DataNode/d2707> , <http://rdf.wikipathways.org/Pathway/WP5545_r139134/DataNode/bce60> , <http://rdf.wikipathways.org/Pathway/WP5545_r139134/DataNode/e42a5> , <http://rdf.wikipathways.org/Pathway/WP5545_r139134/DataNode/d0135> , <http://rdf.wikipathways.org/Pathway/WP5545_r139134/DataNode/aaf88> , <http://rdf.wikipathways.org/Pathway/WP5545_r139134/DataNode/a3e09> , <http://rdf.wikipathways.org/Pathway/WP5545_r139134/DataNode/c4dbe> , <http://rdf.wikipathways.org/Pathway/WP5545_r139134/DataNode/c8496> , <http://rdf.wikipathways.org/Pathway/WP5545_r139134/DataNode/f8cee> , <http://rdf.wikipathways.org/Pathway/WP5545_r139134/DataNode/c5db2> , <http://rdf.wikipathways.org/Pathway/WP5545_r139134/DataNode/e448a> ;
        gpml:hasGroup        <http://rdf.wikipathways.org/Pathway/WP5545_r139134/Group/c5732> , <http://rdf.wikipathways.org/Pathway/WP5545_r139134/Group/b7d63> ;
        gpml:hasInfoBox      <http://rdf.wikipathways.org/Pathway/WP5545_r139134/InfoBox/90ccdba558b10b76d9c6171520d1227b> ;
        gpml:hasInteraction  <http://rdf.wikipathways.org/Pathway/WP5545_r139134/Interaction/b37d7> , <http://rdf.wikipathways.org/Pathway/WP5545_r139134/Interaction/id1ec4c874> , <http://rdf.wikipathways.org/Pathway/WP5545_r139134/Interaction/e8366> , <http://rdf.wikipathways.org/Pathway/WP5545_r139134/Interaction/idc2941205> , <http://rdf.wikipathways.org/Pathway/WP5545_r139134/Interaction/d313f> , <http://rdf.wikipathways.org/Pathway/WP5545_r139134/Interaction/e2dfe> , <http://rdf.wikipathways.org/Pathway/WP5545_r139134/Interaction/ba7a4> , <http://rdf.wikipathways.org/Pathway/WP5545_r139134/Interaction/id782dadbb> , <http://rdf.wikipathways.org/Pathway/WP5545_r139134/Interaction/dc49e> , <http://rdf.wikipathways.org/Pathway/WP5545_r139134/Interaction/id11bd7f2> , <http://rdf.wikipathways.org/Pathway/WP5545_r139134/Interaction/a9943> , <http://rdf.wikipathways.org/Pathway/WP5545_r139134/Interaction/id34f04aed> , <http://rdf.wikipathways.org/Pathway/WP5545_r139134/Interaction/fba40> ;
        gpml:hasLabel        <http://rdf.wikipathways.org/Pathway/WP5545_r139134/Label/b92dd> ;
        gpml:last-Modified   "20250522233038" ;
        gpml:name            "Fibrotic response of trabecular meshwork cells to TGFB3 and ENPP2 in aqueous humor" ;
        gpml:organism        "Homo sapiens" ;
        gpml:version         "WP5545_r139134" .

<http://rdf.wikipathways.org/Pathway/WP5545_r139134/DataNode/e42a5>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5545_r139134> , <http://rdf.wikipathways.org/Pathway/WP5545_r139134/Group/c5732> ;
        gpml:align           "Center" ;
        gpml:centerX         "214.28221052157795"^^xsd:double ;
        gpml:centerY         "431.02645020476086"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "e42a5" ;
        gpml:groupRef        "d8621" ;
        gpml:hasComment      <http://rdf.wikipathways.org/Pathway/WP5545_r139134/Comment/196b0887c11f5262736a2b6cf84962c> ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "ACTA2" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "90.0"^^xsd:double ;
        gpml:xrefDataSource  "Entrez Gene" ;
        gpml:xrefId          "59" ;
        gpml:zorder          "33017"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5545_r139134/Interaction/b37d7>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP5545_r139134> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "b37d7" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP5545_r139134/Interaction/b37d7/Point/9fed4b1e4289be5117c53410e09994ae> , <http://rdf.wikipathways.org/Pathway/WP5545_r139134/Interaction/b37d7/Point/783778a72037d897202b7a894636df1> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "33021"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5545_r139134/Interaction/id34f04aed/Point/cc13397e8040cba488d9ef2e97c0373d>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5545_r139134> , <http://rdf.wikipathways.org/Pathway/WP5545_r139134/Interaction/id34f04aed> ;
        gpml:graphRef     "a3e09" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "167.59259259259255"^^xsd:double ;
        gpml:y            "343.26234192880463"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5545_r139134/Comment/2507cd4eafca925f292f279995493ee5>
        rdf:type          gpml:Comment ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5545_r139134/DataNode/c4dbe> ;
        gpml:commentText  "alternative name: CTGF" .

<http://rdf.wikipathways.org/Pathway/WP5545_r139134/DataNode/d7a95>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5545_r139134> ;
        gpml:align           "Center" ;
        gpml:centerX         "573.8569371315389"^^xsd:double ;
        gpml:centerY         "45.333862112416085"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "d7a95" ;
        gpml:hasComment      <http://rdf.wikipathways.org/Pathway/WP5545_r139134/Comment/ad09e29d00812340c68a18df73f15ad9> ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "TGFB1" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "90.0"^^xsd:double ;
        gpml:xrefDataSource  "Entrez Gene" ;
        gpml:xrefId          "7040" ;
        gpml:zorder          "33018"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5545_r139134/DataNode/e25da>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5545_r139134> ;
        gpml:align           "Center" ;
        gpml:centerX         "59.15069078799306"^^xsd:double ;
        gpml:centerY         "124.05050402772142"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "e25da" ;
        gpml:hasComment      <http://rdf.wikipathways.org/Pathway/WP5545_r139134/Comment/e187a9939bc89e605d5684a7ec610f42> ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "STAT3" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "90.0"^^xsd:double ;
        gpml:xrefDataSource  "Entrez Gene" ;
        gpml:xrefId          "6774" ;
        gpml:zorder          "33002"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5545_r139134/Interaction/fba40/Point/abbe7c3cc24704439bd05bc140af6c29>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5545_r139134> , <http://rdf.wikipathways.org/Pathway/WP5545_r139134/Interaction/fba40> ;
        gpml:graphRef     "cdeea" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "573.8569371315389"^^xsd:double ;
        gpml:y            "175.9325637910086"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5545_r139134/Interaction/b37d7/Point/783778a72037d897202b7a894636df1>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5545_r139134> , <http://rdf.wikipathways.org/Pathway/WP5545_r139134/Interaction/b37d7> ;
        gpml:graphRef     "c5db2" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "167.59259259259255"^^xsd:double ;
        gpml:y            "72.08333333333336"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5545_r139134/Interaction/d313f>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP5545_r139134> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "d313f" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP5545_r139134/Interaction/d313f/Point/66c40335250bcbb840a6735c5ac5bc63> , <http://rdf.wikipathways.org/Pathway/WP5545_r139134/Interaction/d313f/Point/2ff6cb254f4d58bfa646637b27304bf2> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "33028"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5545_r139134/Group/b7d63>
        rdf:type          gpml:Group ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5545_r139134> ;
        gpml:graphId      "b7d63" ;
        gpml:groupId      "e4e6b" ;
        gpml:style        "Group" .

<http://rdf.wikipathways.org/Pathway/WP5545_r139134/DataNode/c9771>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5545_r139134> , <http://rdf.wikipathways.org/Pathway/WP5545_r139134/Group/b7d63> ;
        gpml:align           "Center" ;
        gpml:centerX         "322.33810359569657"^^xsd:double ;
        gpml:centerY         "130.5404234732913"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "c9771" ;
        gpml:groupRef        "e4e6b" ;
        gpml:hasComment      <http://rdf.wikipathways.org/Pathway/WP5545_r139134/Comment/861774c6170ceeb9b6499ae4432b1512> ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "MAPK9" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "90.0"^^xsd:double ;
        gpml:xrefDataSource  "Entrez Gene" ;
        gpml:xrefId          "5601" ;
        gpml:zorder          "33013"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5545_r139134/Interaction/dc49e/Point/6e0a8d43aa2518213fff16c96db46c6a>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5545_r139134> , <http://rdf.wikipathways.org/Pathway/WP5545_r139134/Interaction/dc49e> ;
        gpml:graphRef     "c5db2" ;
        gpml:relX         "1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "212.59259259259255"^^xsd:double ;
        gpml:y            "59.58333333333336"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5545_r139134/Interaction/id1ec4c874>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP5545_r139134> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "id1ec4c874" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP5545_r139134/Interaction/id1ec4c874/Point/aabf1bd82f6fbcfc34450c84a8a953ad> , <http://rdf.wikipathways.org/Pathway/WP5545_r139134/Interaction/id1ec4c874/Point/920abad66537b828af6f0599314551bf> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5545_r139134/DataNode/c4dbe>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5545_r139134/Group/c5732> , <http://rdf.wikipathways.org/Pathway/WP5545_r139134> ;
        gpml:align           "Center" ;
        gpml:centerX         "214.282210521578"^^xsd:double ;
        gpml:centerY         "406.0264502047608"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "c4dbe" ;
        gpml:groupRef        "d8621" ;
        gpml:hasComment      <http://rdf.wikipathways.org/Pathway/WP5545_r139134/Comment/2507cd4eafca925f292f279995493ee5> ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "CCN2" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "90.0"^^xsd:double ;
        gpml:xrefDataSource  "Entrez Gene" ;
        gpml:xrefId          "1490" ;
        gpml:zorder          "33015"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5545_r139134/Interaction/id34f04aed>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP5545_r139134> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "id34f04aed" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP5545_r139134/Interaction/id34f04aed/Point/da6960ae29fc27bd06a0cf118544687c> , <http://rdf.wikipathways.org/Pathway/WP5545_r139134/Interaction/id34f04aed/Point/cc13397e8040cba488d9ef2e97c0373d> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5545_r139134/Comment/e187a9939bc89e605d5684a7ec610f42>
        rdf:type          gpml:Comment ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5545_r139134/DataNode/e25da> ;
        gpml:commentText  "OCR lexicon match: STAT3" .

<http://rdf.wikipathways.org/Pathway/WP5545_r139134/Interaction/ba7a4/Point/795377ad664f8df538a808b3b597a722>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5545_r139134> , <http://rdf.wikipathways.org/Pathway/WP5545_r139134/Interaction/ba7a4> ;
        gpml:graphRef     "b7d63" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "269.33810359569657"^^xsd:double ;
        gpml:y            "130.54042347329124"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5545_r139134/Interaction/e2dfe/Point/1ed081588ff9b56e2381d90acbff3236>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5545_r139134> , <http://rdf.wikipathways.org/Pathway/WP5545_r139134/Interaction/e2dfe> ;
        gpml:graphRef     "e25da" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "59.15069078799306"^^xsd:double ;
        gpml:y            "136.55050402772142"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5545_r139134/DataNode/d0135>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5545_r139134> ;
        gpml:align           "Center" ;
        gpml:centerX         "167.5925925925925"^^xsd:double ;
        gpml:centerY         "188.4325637910086"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "d0135" ;
        gpml:hasComment      <http://rdf.wikipathways.org/Pathway/WP5545_r139134/Comment/1030525dc0f8d58e1cb70ae5aeb095a9> ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "ENPP2" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "90.0"^^xsd:double ;
        gpml:xrefDataSource  "Entrez Gene" ;
        gpml:xrefId          "5168" ;
        gpml:zorder          "32768"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5545_r139134/Comment/f88fdaa8b87bed8c9e67afad0cdcdb3a>
        rdf:type          gpml:Comment ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5545_r139134/DataNode/bf517> ;
        gpml:commentText  "OCR lexicon match: LPA" .

<http://rdf.wikipathways.org/Pathway/WP5545_r139134/Group/c5732>
        rdf:type          gpml:Group ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5545_r139134> ;
        gpml:graphId      "c5732" ;
        gpml:groupId      "d8621" ;
        gpml:style        "Group" .

<http://rdf.wikipathways.org/Pathway/WP5545_r139134/DataNode/bf517>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5545_r139134> ;
        gpml:align           "Center" ;
        gpml:centerX         "167.59259259259255"^^xsd:double ;
        gpml:centerY         "265.66513658251023"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "bf517" ;
        gpml:hasComment      <http://rdf.wikipathways.org/Pathway/WP5545_r139134/Comment/f88fdaa8b87bed8c9e67afad0cdcdb3a> ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "LPA" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "90.0"^^xsd:double ;
        gpml:xrefDataSource  "Entrez Gene" ;
        gpml:xrefId          "4018" ;
        gpml:zorder          "33006"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5545_r139134/DataNode/c5db2>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5545_r139134> ;
        gpml:align           "Center" ;
        gpml:centerX         "167.59259259259255"^^xsd:double ;
        gpml:centerY         "59.58333333333336"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "c5db2" ;
        gpml:hasComment      <http://rdf.wikipathways.org/Pathway/WP5545_r139134/Comment/b88d5b74e099ea2e669b0069eaf163bb> ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "TGFB3" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "90.0"^^xsd:double ;
        gpml:xrefDataSource  "Entrez Gene" ;
        gpml:xrefId          "7043" ;
        gpml:zorder          "33001"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5545_r139134/Comment/87bee201aa936431d0eeca2287915125>
        rdf:type          gpml:Comment ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5545_r139134/DataNode/cdeea> ;
        gpml:commentText  "OCR lexicon match: SMAD3" .

<http://rdf.wikipathways.org/Pathway/WP5545_r139134/Interaction/ba7a4>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP5545_r139134> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "ba7a4" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP5545_r139134/Interaction/ba7a4/Point/e99455dd85e40a8cf5417d08ee3c7620> , <http://rdf.wikipathways.org/Pathway/WP5545_r139134/Interaction/ba7a4/Point/795377ad664f8df538a808b3b597a722> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "33023"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5545_r139134/Interaction/id11bd7f2/Point/9f13d9849e5632d18ae8ae877f04519f>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5545_r139134> , <http://rdf.wikipathways.org/Pathway/WP5545_r139134/Interaction/id11bd7f2> ;
        gpml:graphRef     "cdeea" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "528.8569371315389"^^xsd:double ;
        gpml:y            "188.4325637910086"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5545_r139134/Label/b92dd>
        rdf:type             gpml:Label ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5545_r139134> ;
        gpml:align           "Center" ;
        gpml:centerX         "455.41008505467835"^^xsd:double ;
        gpml:centerY         "128.8942891859055"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "b92dd" ;
        gpml:height          "75.33414337788578"^^xsd:double ;
        gpml:href            "" ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "None" ;
        gpml:textlabel       "JNK consists of 10 isoforms:\nJNK1 (4 isoforms)-> MAPK8\nJNK2 (four isoforms)-> MAPK9\nJNK3 (two isoforms)-> MAPK10" ;
        gpml:valign          "Middle" ;
        gpml:width           "202.9586877278241"^^xsd:double ;
        gpml:zorder          "28672"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5545_r139134/Interaction/b37d7/Point/9fed4b1e4289be5117c53410e09994ae>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5545_r139134> , <http://rdf.wikipathways.org/Pathway/WP5545_r139134/Interaction/b37d7> ;
        gpml:graphRef     "b7d63" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "-0.5"^^xsd:double ;
        gpml:x            "269.33810359569657"^^xsd:double ;
        gpml:y            "107.79042347329121"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5545_r139134/Interaction/a9943/Point/e93c6510633a9fecde87080ef20ec4c2>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5545_r139134> , <http://rdf.wikipathways.org/Pathway/WP5545_r139134/Interaction/a9943> ;
        gpml:graphRef     "d7a95" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "528.8569371315389"^^xsd:double ;
        gpml:y            "45.333862112416085"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5545_r139134/Interaction/e2dfe>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP5545_r139134> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "e2dfe" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP5545_r139134/Interaction/e2dfe/Point/1ed081588ff9b56e2381d90acbff3236> , <http://rdf.wikipathways.org/Pathway/WP5545_r139134/Interaction/e2dfe/Point/eba1de28f5174788c51a8ec899562bbf> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "33022"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5545_r139134/DataNode/c8496>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5545_r139134> , <http://rdf.wikipathways.org/Pathway/WP5545_r139134/Group/b7d63> ;
        gpml:align           "Center" ;
        gpml:centerX         "322.33810359569657"^^xsd:double ;
        gpml:centerY         "105.54042347329121"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "c8496" ;
        gpml:groupRef        "e4e6b" ;
        gpml:hasComment      <http://rdf.wikipathways.org/Pathway/WP5545_r139134/Comment/861774c6170ceeb9b6499ae4432b1512> ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "MAPK8" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "90.0"^^xsd:double ;
        gpml:xrefDataSource  "Entrez Gene" ;
        gpml:xrefId          "5599" ;
        gpml:zorder          "33012"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5545_r139134/Comment/e02c91475cb365cdd9455753a978d650>
        rdf:type          gpml:Comment ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5545_r139134/DataNode/a3e09> ;
        gpml:commentText  "OCR lexicon match: RHO" .

<http://rdf.wikipathways.org/Pathway/WP5545_r139134/Interaction/id11bd7f2>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP5545_r139134> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "id11bd7f2" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP5545_r139134/Interaction/id11bd7f2/Point/89308f98e2e353dc317f20fa3f666e5e> , <http://rdf.wikipathways.org/Pathway/WP5545_r139134/Interaction/id11bd7f2/Point/9f13d9849e5632d18ae8ae877f04519f> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5545_r139134/Interaction/id782dadbb/Point/97b6d8f4be3056556197fb5410447e25>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5545_r139134> , <http://rdf.wikipathways.org/Pathway/WP5545_r139134/Interaction/id782dadbb> ;
        gpml:graphRef     "c5db2" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "167.59259259259255"^^xsd:double ;
        gpml:y            "72.08333333333336"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5545_r139134/Comment/8d6eebfd6bdf60d09bd5215aef12104d>
        rdf:type          gpml:Comment ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5545_r139134/DataNode/f8cee> ;
        gpml:commentText  "OCR lexicon match: COL1A1" .

<http://rdf.wikipathways.org/Pathway/WP5545_r139134/Interaction/idc2941205/Point/e59e89ca1c259172ecbf48949b0f6591>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5545_r139134> , <http://rdf.wikipathways.org/Pathway/WP5545_r139134/Interaction/idc2941205> ;
        gpml:graphRef     "d0135" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "167.5925925925925"^^xsd:double ;
        gpml:y            "200.9325637910086"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5545_r139134/Comment/86a3314cf47e356964305d297522e5b9>
        rdf:type          gpml:Comment ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5545_r139134/DataNode/bce60> ;
        gpml:commentText  "\"Fibronectin\" originally" .

<http://rdf.wikipathways.org/Pathway/WP5545_r139134/InfoBox/90ccdba558b10b76d9c6171520d1227b>
        rdf:type          gpml:InfoBox ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5545_r139134> ;
        gpml:centerX      "0.0"^^xsd:double ;
        gpml:centerY      "0.0"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5545_r139134/Interaction/e8366>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP5545_r139134> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "e8366" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP5545_r139134/Interaction/e8366/Point/d2c9dba13917a728aad556c931edb3cf> , <http://rdf.wikipathways.org/Pathway/WP5545_r139134/Interaction/e8366/Point/183efa6c796d14446c6c9253ccecbc70> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "33024"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5545_r139134/Interaction/dc49e/Point/53b07c85dfa2d58118444c5b51c8c0d3>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5545_r139134> , <http://rdf.wikipathways.org/Pathway/WP5545_r139134/Interaction/dc49e> ;
        gpml:graphRef     "aaf88" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "528.8569371315389"^^xsd:double ;
        gpml:y            "70.33386211241604"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5545_r139134/Comment/f357630c646d9824aaec4961c1894c92>
        rdf:type          gpml:Comment ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5545_r139134/DataNode/aaf88> ;
        gpml:commentText  "OCR lexicon match: TGF-B2" .

<http://rdf.wikipathways.org/Pathway/WP5545_r139134/DataNode/f8cee>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5545_r139134> , <http://rdf.wikipathways.org/Pathway/WP5545_r139134/Group/c5732> ;
        gpml:align           "Center" ;
        gpml:centerX         "124.2822105215779"^^xsd:double ;
        gpml:centerY         "406.02645020476086"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "f8cee" ;
        gpml:groupRef        "d8621" ;
        gpml:hasComment      <http://rdf.wikipathways.org/Pathway/WP5545_r139134/Comment/8d6eebfd6bdf60d09bd5215aef12104d> ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "COL1A1" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "90.0"^^xsd:double ;
        gpml:xrefDataSource  "Entrez Gene" ;
        gpml:xrefId          "1277" ;
        gpml:zorder          "33016"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5545_r139134/Interaction/ba7a4/Point/e99455dd85e40a8cf5417d08ee3c7620>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5545_r139134> , <http://rdf.wikipathways.org/Pathway/WP5545_r139134/Interaction/ba7a4> ;
        gpml:graphRef     "d0135" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "167.5925925925925"^^xsd:double ;
        gpml:y            "175.9325637910086"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5545_r139134/Interaction/e8366/Point/183efa6c796d14446c6c9253ccecbc70>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5545_r139134> , <http://rdf.wikipathways.org/Pathway/WP5545_r139134/Interaction/e8366> ;
        gpml:graphRef     "a3e09" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "167.59259259259255"^^xsd:double ;
        gpml:y            "318.26234192880463"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5545_r139134/Interaction/e8366/Point/d2c9dba13917a728aad556c931edb3cf>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5545_r139134> , <http://rdf.wikipathways.org/Pathway/WP5545_r139134/Interaction/e8366> ;
        gpml:graphRef     "bf517" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "167.59259259259255"^^xsd:double ;
        gpml:y            "278.16513658251023"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5545_r139134/Comment/1030525dc0f8d58e1cb70ae5aeb095a9>
        rdf:type          gpml:Comment ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5545_r139134/DataNode/d0135> ;
        gpml:commentText  "alternative name: ATX" .

<http://rdf.wikipathways.org/Pathway/WP5545_r139134/Interaction/e2dfe/Point/eba1de28f5174788c51a8ec899562bbf>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5545_r139134> , <http://rdf.wikipathways.org/Pathway/WP5545_r139134/Interaction/e2dfe> ;
        gpml:graphRef     "d0135" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "167.5925925925925"^^xsd:double ;
        gpml:y            "175.9325637910086"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5545_r139134/DataNode/a3e09>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5545_r139134> ;
        gpml:align           "Center" ;
        gpml:centerX         "167.59259259259255"^^xsd:double ;
        gpml:centerY         "330.76234192880463"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "a3e09" ;
        gpml:hasComment      <http://rdf.wikipathways.org/Pathway/WP5545_r139134/Comment/e02c91475cb365cdd9455753a978d650> ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "RHO" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "90.0"^^xsd:double ;
        gpml:xrefDataSource  "Entrez Gene" ;
        gpml:xrefId          "6010" ;
        gpml:zorder          "33007"^^xsd:long .
