@prefix biopax:  <http://www.biopax.org/release/biopax-level3.owl#> .
@prefix cito:    <http://purl.org/spar/cito/> .
@prefix dc:      <http://purl.org/dc/elements/1.1/> .
@prefix dcterms: <http://purl.org/dc/terms/> .
@prefix foaf:    <http://xmlns.com/foaf/0.1/> .
@prefix freq:    <http://purl.org/cld/freq/> .
@prefix gpml:    <http://vocabularies.wikipathways.org/gpml#> .
@prefix obo:     <http://purl.obolibrary.org/obo/> .
@prefix owl:     <http://www.w3.org/2002/07/owl#> .
@prefix pav:     <http://purl.org/pav/> .
@prefix prov:    <http://www.w3.org/ns/prov#> .
@prefix rdf:     <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix rdfs:    <http://www.w3.org/2000/01/rdf-schema#> .
@prefix skos:    <http://www.w3.org/2004/02/skos/core#> .
@prefix void:    <http://rdfs.org/ns/void#> .
@prefix wp:      <http://vocabularies.wikipathways.org/wp#> .
@prefix wprdf:   <http://rdf.wikipathways.org/> .
@prefix xsd:     <http://www.w3.org/2001/XMLSchema#> .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Label/ab697>
        rdf:type             gpml:Label ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5345_r134459> ;
        gpml:align           "Center" ;
        gpml:centerX         "1600.2389898523365"^^xsd:double ;
        gpml:centerY         "575.7204803608656"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "ab697" ;
        gpml:height          "31.941069258809208"^^xsd:double ;
        gpml:href            "" ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "None" ;
        gpml:textlabel       "Long-term T-cell\nimunitry" ;
        gpml:valign          "Middle" ;
        gpml:width           "97.24787363304986"^^xsd:double ;
        gpml:zorder          "28672"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/ddc66>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Group/a72b9> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459> ;
        gpml:align           "Center" ;
        gpml:centerX         "754.6749015177063"^^xsd:double ;
        gpml:centerY         "1211.7102444433049"^^xsd:double ;
        gpml:color           "14961e" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Bold" ;
        gpml:graphId         "ddc66" ;
        gpml:groupRef        "d2150" ;
        gpml:height          "46.12587165252694"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "RoundedRectangle" ;
        gpml:textlabel       "Post-translational \nprotein phosphorylation \n" ;
        gpml:type            "Pathway" ;
        gpml:valign          "Middle" ;
        gpml:width           "166.0"^^xsd:double ;
        gpml:xrefDataSource  "WikiPathways" ;
        gpml:xrefId          "WP4110" ;
        gpml:zorder          "33037"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/a022b>
        rdf:type                 gpml:Interaction ;
        dcterms:isPartOf         <http://rdf.wikipathways.org/Pathway/WP5345_r134459> ;
        gpml:biopaxRef           "f52" ;
        gpml:color               "0" ;
        gpml:connectorType       "Straight" ;
        gpml:graphId             "a022b" ;
        gpml:hasPoint            <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/a022b/Point/7d23140ac34e46a384f6203ba37581fc> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/a022b/Point/1880f1b2b773b0d1f42cc13137c60f69> ;
        gpml:hasPublicationXref  <https://identifiers.org/pubmed/32697989> ;
        gpml:lineStyle           "Solid" ;
        gpml:lineThickness       "1.0"^^xsd:double ;
        gpml:zorder              "33073"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/id14d19cb3>
        rdf:type                 gpml:Interaction ;
        dcterms:isPartOf         <http://rdf.wikipathways.org/Pathway/WP5345_r134459> ;
        gpml:biopaxRef           "d49" ;
        gpml:color               "0" ;
        gpml:connectorType       "Straight" ;
        gpml:graphId             "id14d19cb3" ;
        gpml:hasPoint            <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/id14d19cb3/Point/c1fcedeff16048c020bf6dddfa66d0e8> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/id14d19cb3/Point/ae4b73b61a4b1be506d6f1670c9033d1> ;
        gpml:hasPublicationXref  <https://identifiers.org/pubmed/22969013> ;
        gpml:lineStyle           "Solid" ;
        gpml:lineThickness       "1.0"^^xsd:double ;
        gpml:zorder              "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/cfd31>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Group/eb46d> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459> ;
        gpml:align           "Center" ;
        gpml:centerX         "1604.2167662043075"^^xsd:double ;
        gpml:centerY         "1219.6537779415921"^^xsd:double ;
        gpml:color           "14961e" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Bold" ;
        gpml:graphId         "cfd31" ;
        gpml:groupRef        "eb0e2" ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "RoundedRectangle" ;
        gpml:textlabel       "Apoptosis" ;
        gpml:type            "Pathway" ;
        gpml:valign          "Middle" ;
        gpml:width           "90.0"^^xsd:double ;
        gpml:xrefDataSource  "WikiPathways" ;
        gpml:xrefId          "WP254" ;
        gpml:zorder          "32942"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/c8fe1/Point/cef256783700cb29d423d115b4e88be7>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5345_r134459> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/c8fe1> ;
        gpml:graphRef     "ab8be" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "2318.096491228076"^^xsd:double ;
        gpml:y            "360.1491228070183"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/a4429>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5345_r134459> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Group/dcdb3> ;
        gpml:align           "Center" ;
        gpml:centerX         "792.7369964105261"^^xsd:double ;
        gpml:centerY         "664.5317347610073"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "a4429" ;
        gpml:groupRef        "ee9fc" ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "RoundedRectangle" ;
        gpml:textlabel       "E3 ubiquitin-protein ligase complex" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "211.0"^^xsd:double ;
        gpml:xrefDataSource  "" ;
        gpml:xrefId          "" ;
        gpml:zorder          "32987"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/ceda9/Point/3dc5b9917a09fe041b6899e1b07a3f8c>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5345_r134459> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/ceda9> ;
        gpml:graphRef     "e1ad0" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "2258.655008430647"^^xsd:double ;
        gpml:y            "1368.5480790077872"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/id11c8c4b1>
        rdf:type                 gpml:Interaction ;
        dcterms:isPartOf         <http://rdf.wikipathways.org/Pathway/WP5345_r134459> ;
        gpml:biopaxRef           "fcb" ;
        gpml:color               "0" ;
        gpml:connectorType       "Straight" ;
        gpml:graphId             "id11c8c4b1" ;
        gpml:hasPoint            <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/id11c8c4b1/Point/f93ed51351ee80ec16a3d974169d2f7a> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/id11c8c4b1/Point/593f1b15fd4b1d1801979be75fef2a46> ;
        gpml:hasPublicationXref  <https://identifiers.org/pubmed/35217789> ;
        gpml:lineStyle           "Solid" ;
        gpml:lineThickness       "1.0"^^xsd:double ;
        gpml:zorder              "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/be3ea>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5345_r134459> ;
        gpml:align           "Center" ;
        gpml:centerX         "68.09649122807053"^^xsd:double ;
        gpml:centerY         "347.6491228070182"^^xsd:double ;
        gpml:color           "9900cc" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "be3ea" ;
        gpml:hasComment      <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Comment/8d18617682221b1c0c3449c56c99b9aa> ;
        gpml:height          "25.000000000000004"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "MIR6859-1" ;
        gpml:type            "Rna" ;
        gpml:valign          "Middle" ;
        gpml:width           "90.0000000000002"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000278267" ;
        gpml:zorder          "32800"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/idb0eb46ba/Point/b931b1f07f47c508ff4dacff8b02b0d3>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5345_r134459> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/idb0eb46ba> ;
        gpml:graphRef     "bd9a8" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "878.3164144910663"^^xsd:double ;
        gpml:y            "399.92722893819627"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/ed66c>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5345_r134459> ;
        gpml:align           "Center" ;
        gpml:centerX         "1508.0648523181721"^^xsd:double ;
        gpml:centerY         "531.2961006464282"^^xsd:double ;
        gpml:color           "14961e" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Bold" ;
        gpml:graphId         "ed66c" ;
        gpml:height          "37.12713976876648"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "RoundedRectangle" ;
        gpml:textlabel       "NFkB activation\nvia TRAF2/NIK" ;
        gpml:type            "Pathway" ;
        gpml:valign          "Middle" ;
        gpml:width           "111.130820073844"^^xsd:double ;
        gpml:xrefDataSource  "WikiPathways" ;
        gpml:xrefId          "WP3849" ;
        gpml:zorder          "32768"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/b9e93/Point/208d0125106258e11efa07bac649fe7d>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5345_r134459> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/b9e93> ;
        gpml:graphRef     "e9d5d" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "737.6731601731599"^^xsd:double ;
        gpml:y            "467.1536796536798"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/id16ee34f8/Point/ca18f2d1a545f5c18bf17fbd4c012009>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5345_r134459> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/id16ee34f8> ;
        gpml:graphRef     "fd350" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "1508.0964912280747"^^xsd:double ;
        gpml:y            "360.14912280701833"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/a68f8/Point/837fbb4c49d4ea36c04554afd80f3433>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5345_r134459> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/a68f8> ;
        gpml:graphRef     "f7437" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "2506.0622303648584"^^xsd:double ;
        gpml:y            "1076.0136751595667"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/id21fea3ee>
        rdf:type                 gpml:Interaction ;
        dcterms:isPartOf         <http://rdf.wikipathways.org/Pathway/WP5345_r134459> ;
        gpml:biopaxRef           "fcb" ;
        gpml:color               "0" ;
        gpml:connectorType       "Straight" ;
        gpml:graphId             "id21fea3ee" ;
        gpml:hasComment          <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Comment/1b7b7494b3c5d4c22b1f80668bca135b> ;
        gpml:hasPoint            <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/id21fea3ee/Point/a1b9962d2ab7d3115240a41a93e44eee> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/id21fea3ee/Point/5999a36205813a6f52935867a22375a4> ;
        gpml:hasPublicationXref  <https://identifiers.org/pubmed/35217789> ;
        gpml:lineStyle           "Solid" ;
        gpml:lineThickness       "1.0"^^xsd:double ;
        gpml:zorder              "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Label/f3078>
        rdf:type             gpml:Label ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5345_r134459> ;
        gpml:align           "Center" ;
        gpml:centerX         "75.46027655682148"^^xsd:double ;
        gpml:centerY         "303.6254930262783"^^xsd:double ;
        gpml:color           "cc0000" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "f3078" ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:href            "" ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "None" ;
        gpml:textlabel       "Chromosome 1:0\n" ;
        gpml:valign          "Middle" ;
        gpml:width           "126.11468382438872"^^xsd:double ;
        gpml:zorder          "32795"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/faf93>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Group/e5817> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459> ;
        gpml:align           "Center" ;
        gpml:centerX         "886.0622303648587"^^xsd:double ;
        gpml:centerY         "1213.513675159567"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "faf93" ;
        gpml:groupRef        "d8018" ;
        gpml:height          "24.999999999999936"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "DKK3" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "89.99999999999999"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000050165" ;
        gpml:zorder          "33026"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/aaf46/Point/8f3edb2532090844199fa0bf509e6ca7>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5345_r134459> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/aaf46> ;
        gpml:graphRef     "b70b0" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "2326.0622303648584"^^xsd:double ;
        gpml:y            "1076.0136751595667"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/idc6f000bb>
        rdf:type                 gpml:Interaction ;
        dcterms:isPartOf         <http://rdf.wikipathways.org/Pathway/WP5345_r134459> ;
        gpml:biopaxRef           "b02" ;
        gpml:color               "0" ;
        gpml:connectorType       "Straight" ;
        gpml:graphId             "idc6f000bb" ;
        gpml:hasPoint            <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/idc6f000bb/Point/153b46cf919ab9f627c0e042cefb44dc> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/idc6f000bb/Point/54aa78206794b3bcbcb7c8e052acf1b0> ;
        gpml:hasPublicationXref  <https://identifiers.org/pubmed/35562682> ;
        gpml:lineStyle           "Solid" ;
        gpml:lineThickness       "1.0"^^xsd:double ;
        gpml:zorder              "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/d6ae0>
        rdf:type                 gpml:Interaction ;
        dcterms:isPartOf         <http://rdf.wikipathways.org/Pathway/WP5345_r134459> ;
        gpml:biopaxRef           "c2d" ;
        gpml:color               "0" ;
        gpml:connectorType       "Straight" ;
        gpml:graphId             "d6ae0" ;
        gpml:hasPoint            <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/d6ae0/Point/2076a7455d648554358d82e4d7d298f0> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/d6ae0/Point/e4490fa156d1472df7d633b39b5f3c34> ;
        gpml:hasPublicationXref  <https://identifiers.org/pubmed/19587085> ;
        gpml:lineStyle           "Solid" ;
        gpml:lineThickness       "1.0"^^xsd:double ;
        gpml:zorder              "33064"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/da179/Point/5ec1b9e00c629230fd4baa06ee60134>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5345_r134459> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/da179> ;
        gpml:graphRef     "aa3e7" ;
        gpml:relX         "-0.5"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "332.0047097246517"^^xsd:double ;
        gpml:y            "419.52265435146376"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/f5e12>
        rdf:type                 gpml:Interaction ;
        dcterms:isPartOf         <http://rdf.wikipathways.org/Pathway/WP5345_r134459> ;
        gpml:biopaxRef           "ecd" ;
        gpml:color               "0" ;
        gpml:connectorType       "Straight" ;
        gpml:graphId             "f5e12" ;
        gpml:hasPoint            <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/f5e12/Point/deb057d0dc85d9cffe90b73be3a645ff> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/f5e12/Point/e3ddace8e51c543ec99017404c485ac3> ;
        gpml:hasPublicationXref  <https://identifiers.org/pubmed/28650474> ;
        gpml:lineStyle           "Solid" ;
        gpml:lineThickness       "1.0"^^xsd:double ;
        gpml:zorder              "32924"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/c6ff8>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5345_r134459> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Group/e3720> ;
        gpml:align           "Center" ;
        gpml:centerX         "2765.7705424919704"^^xsd:double ;
        gpml:centerY         "510.9517063499951"^^xsd:double ;
        gpml:color           "ff" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "c6ff8" ;
        gpml:groupRef        "e3720" ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "C1P" ;
        gpml:type            "Metabolite" ;
        gpml:valign          "Middle" ;
        gpml:width           "90.0"^^xsd:double ;
        gpml:xrefDataSource  "ChEBI" ;
        gpml:xrefId          "72963" ;
        gpml:zorder          "33128"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/dcdfd/Point/b1552b5c0cacf0dc36ddf328e0c0c2c3>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5345_r134459> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/dcdfd> ;
        gpml:graphRef     "ecd6e" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "698.0964912280722"^^xsd:double ;
        gpml:y            "360.1491228070183"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/ceb80/Point/3a085b0d3628fcd687164bec7b62a82>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5345_r134459> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/ceb80> ;
        gpml:graphRef     "fcf65" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "2236.0622303648584"^^xsd:double ;
        gpml:y            "1076.0136751595667"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/a39b1>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5345_r134459> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Group/f323e> ;
        gpml:align           "Center" ;
        gpml:centerX         "1243.59432855465"^^xsd:double ;
        gpml:centerY         "545.7395879036533"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "a39b1" ;
        gpml:groupRef        "acb8e" ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "AGRN" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "90.0"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000188157" ;
        gpml:zorder          "32768"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/fc722/Point/49b842b151e3b42e59b61667adaed68b>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5345_r134459> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/fc722> ;
        gpml:graphRef     "eb90a" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "2386.272655351364"^^xsd:double ;
        gpml:y            "436.218508261184"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/b9bcc/Point/a31c3a606d3a31c8c07c4457a3948cb1>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5345_r134459> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/b9bcc> ;
        gpml:graphRef     "bb14c" ;
        gpml:relX         "0.5"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "2798.5622303648584"^^xsd:double ;
        gpml:y            "1076.0136751595667"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/idc9dacc7a>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP5345_r134459> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "idc9dacc7a" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/idc9dacc7a/Point/f2f2bb41b7931e514f432fde09f78ae4> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/idc9dacc7a/Point/ba25feaa2387d0f3494dfcae9eb6e61c> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/ddc85>
        rdf:type                 gpml:Interaction ;
        dcterms:isPartOf         <http://rdf.wikipathways.org/Pathway/WP5345_r134459> ;
        gpml:biopaxRef           "f52" ;
        gpml:color               "0" ;
        gpml:connectorType       "Straight" ;
        gpml:graphId             "ddc85" ;
        gpml:hasPoint            <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/ddc85/Point/1827a5dcec5aa6ed4bc5db8aa8ed9c8c> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/ddc85/Point/a6249ca6aa3524308c39b7805544adcf> ;
        gpml:hasPublicationXref  <https://identifiers.org/pubmed/32697989> ;
        gpml:lineStyle           "Solid" ;
        gpml:lineThickness       "1.0"^^xsd:double ;
        gpml:zorder              "33067"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/GraphicalLine/cc24a/Point/2a59cb4f121d55075d5c31290029b93a>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5345_r134459> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/GraphicalLine/cc24a> ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "55.47681410098019"^^xsd:double ;
        gpml:y            "1038.592491326425"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/a022b/Point/1880f1b2b773b0d1f42cc13137c60f69>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5345_r134459> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/a022b> ;
        gpml:graphRef     "ebcb4" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "2685.3320894189233"^^xsd:double ;
        gpml:y            "745.6854093996109"^^xsd:double .

<https://identifiers.org/pubmed/28919417>
        rdf:type          gpml:PublicationXref ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/eb90a> ;
        gpml:database     "Pubmed" ;
        gpml:id           "28919417" .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Shape/a4598>
        rdf:type             gpml:shape ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Group/c9272> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459> ;
        gpml:align           "Center" ;
        gpml:centerX         "2964.4533080920073"^^xsd:double ;
        gpml:centerY         "521.2472986979617"^^xsd:double ;
        gpml:color           "c0c0c0" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "a4598" ;
        gpml:groupRef        "c9eb8" ;
        gpml:height          "200.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "3.0"^^xsd:double ;
        gpml:shape           "0.0"^^xsd:double ;
        gpml:shapeType       "Golgi Apparatus" ;
        gpml:textlabel       "" ;
        gpml:valign          "Middle" ;
        gpml:width           "100.0"^^xsd:double ;
        gpml:zorder          "33081"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/fbc0c>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5345_r134459> ;
        gpml:align           "Center" ;
        gpml:centerX         "1788.4095154227005"^^xsd:double ;
        gpml:centerY         "1242.1511723983024"^^xsd:double ;
        gpml:color           "14961e" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Bold" ;
        gpml:graphId         "fbc0c" ;
        gpml:height          "25.5"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "RoundedRectangle" ;
        gpml:textlabel       "PI3K-Akt signaling pathway" ;
        gpml:type            "Pathway" ;
        gpml:valign          "Middle" ;
        gpml:width           "169.0"^^xsd:double ;
        gpml:xrefDataSource  "WikiPathways" ;
        gpml:xrefId          "WP4172" ;
        gpml:zorder          "32957"^^xsd:long .

<https://identifiers.org/pubmed/28011644>
        rdf:type          gpml:PublicationXref ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/f64d4> ;
        gpml:database     "Pubmed" ;
        gpml:id           "28011644" .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/iddc2630e8/Point/9f76dbf219d779ee6e963bc9dcea2d88>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5345_r134459> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/iddc2630e8> ;
        gpml:graphRef     "ce665" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "1148.9863848580037"^^xsd:double ;
        gpml:y            "431.8157978419546"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/idf19bf22/Point/7152a79482257e21237e8d61557e9b30>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5345_r134459> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/idf19bf22> ;
        gpml:graphRef     "adde5" ;
        gpml:relX         "-0.5"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "2965.4499854668943"^^xsd:double ;
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/dfc24/Point/473fabf1eb92d290856c7ff7019e5624>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5345_r134459> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/dfc24> ;
        gpml:graphRef     "eb46d" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "1604.2167662043075"^^xsd:double ;
        gpml:y            "1199.1537779415921"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/d6fe5>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5345_r134459> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Group/a9efb> ;
        gpml:align           "Center" ;
        gpml:centerX         "2948.84249296454"^^xsd:double ;
        gpml:centerY         "694.5023155944624"^^xsd:double ;
        gpml:color           "14961e" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Bold" ;
        gpml:graphId         "d6fe5" ;
        gpml:groupRef        "a7f49" ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "RoundedRectangle" ;
        gpml:textlabel       "NLRP3 Inflammasome" ;
        gpml:type            "Pathway" ;
        gpml:valign          "Middle" ;
        gpml:width           "149.35571687840502"^^xsd:double ;
        gpml:xrefDataSource  "Reactome" ;
        gpml:xrefId          "R-HSA-844456" ;
        gpml:zorder          "33120"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/ae930>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5345_r134459> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Group/c9272> ;
        gpml:align           "Center" ;
        gpml:centerX         "2950.161627135058"^^xsd:double ;
        gpml:centerY         "515.3280480558783"^^xsd:double ;
        gpml:color           "ff" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "ae930" ;
        gpml:groupRef        "c9eb8" ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "C1P" ;
        gpml:type            "Metabolite" ;
        gpml:valign          "Middle" ;
        gpml:width           "90.0"^^xsd:double ;
        gpml:xrefDataSource  "ChEBI" ;
        gpml:xrefId          "72963" ;
        gpml:zorder          "33131"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/id3f86f5b7/Point/938f9cccedbdf6a08b665d738cd32fad>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5345_r134459> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/id3f86f5b7> ;
        gpml:graphRef     "d9f1e" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "1238.0964912280738"^^xsd:double ;
        gpml:y            "360.14912280701833"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/GraphicalLine/cc24a>
        rdf:type            gpml:GraphicalLine ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP5345_r134459> ;
        gpml:color          "ff0000" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "cc24a" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP5345_r134459/GraphicalLine/cc24a/Point/2a59cb4f121d55075d5c31290029b93a> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/GraphicalLine/cc24a/Point/21fe846ff3982ffd250d4870f9403cb6> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "33132"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/f4409>
        rdf:type                 gpml:Interaction ;
        dcterms:isPartOf         <http://rdf.wikipathways.org/Pathway/WP5345_r134459> ;
        gpml:biopaxRef           "ed4" ;
        gpml:color               "0" ;
        gpml:connectorType       "Elbow" ;
        gpml:graphId             "f4409" ;
        gpml:hasPoint            <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/f4409/Point/d3011306bdbb556d8cde14e5abeb6a62> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/f4409/Point/790b72c2790afe22dd3c74036931bd6d> ;
        gpml:hasPublicationXref  <https://identifiers.org/pubmed/17212986> ;
        gpml:lineStyle           "Solid" ;
        gpml:lineThickness       "1.0"^^xsd:double ;
        gpml:zorder              "33061"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/ef2fd/Point/87821fc2bd403598cbfc22aedbf20429>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5345_r134459> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/ef2fd> ;
        gpml:graphRef     "e9d40" ;
        gpml:relX         "1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "2786.5739645506837"^^xsd:double ;
        gpml:y            "1120.0783621448593"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/d9238>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5345_r134459> ;
        gpml:align           "Center" ;
        gpml:centerX         "2948.0964912280774"^^xsd:double ;
        gpml:centerY         "347.6491228070183"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "d9238" ;
        gpml:height          "25.00000000000001"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "TAS1R3" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "90.00000000000001"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000169962" ;
        gpml:zorder          "33088"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/ee8ac>
        rdf:type             gpml:DataNode ;
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/dab5a/Point/38d03f8d640090ac518e5b9bd78a7831>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/e5ccd>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/id7e217d2c/Point/16162b4db425556f8a23aa0f848040ef>
        rdf:type          gpml:Point ;
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<https://identifiers.org/pubmed/27322068>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/InfoBox/3e4bd2eeb7c1cb0e4d064da914b4c927>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/ed25c>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/dab5a/Point/3e623da4d810a8bb273fe6424fbaeda>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/d2730>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/f7437>
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<https://identifiers.org/pubmed/33559681>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Label/f617a>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/e7c7e>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/a6e60>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/ceda9/Point/43eb1fe50c4830ea630ae8f0c8170084>
        rdf:type          gpml:Point ;
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/aaf46/Point/ad0a8dd1d07be4355687716a26e7b50b>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Group/a9efb>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Comment/e2a5cfa28de256efef6c2cd75f66d066>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/id59643fc3/Point/b8b6a2bd1a38b234b5d95a49cb6c6182>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/bb532>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/ide2d4c658/Point/b42d27560b00d4e16d80821ccda2e6d2>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Comment/a7087848b25c98d6bb746553f13a8a91>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/e04c1>
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<https://identifiers.org/pubmed/35978057>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/cfa30>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/id1ec6cf09/Point/69af5a964a34b796364d4121fc80151e>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/id71f6e57f>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/e1fe8>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/idb0eb46ba>
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<https://identifiers.org/pubmed/14983052>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/d11f1>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Label/baff6>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/e7667>
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<https://identifiers.org/pubmed/16322561>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Group/dad9b>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/cee01>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/ecf1c>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/b70b0>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/id5bba33ca>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Label/fb561>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/b9e93/Point/bcdfbf15d7c5dd38e523aaddaf3cc71f>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/idc6f000bb/Point/153b46cf919ab9f627c0e042cefb44dc>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/d11f1/Point/496c9a70aa63863d18ca0f8560f6d4c0>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/b0178>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/ddc85/Point/a6249ca6aa3524308c39b7805544adcf>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/f481b>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/id48119db4>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/id65c177c9/Point/656b4707c7f2f45c36b9df1abf26663b>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Label/d4207>
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        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "d4207" ;
        gpml:height          "20.668401437526278"^^xsd:double ;
        gpml:href            "" ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "None" ;
        gpml:textlabel       "Unknown function" ;
        gpml:valign          "Middle" ;
        gpml:width           "121.57689375000014"^^xsd:double ;
        gpml:zorder          "32933"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/cd670>
        rdf:type                 gpml:Interaction ;
        dcterms:isPartOf         <http://rdf.wikipathways.org/Pathway/WP5345_r134459> ;
        gpml:biopaxRef           "e02" ;
        gpml:color               "0" ;
        gpml:connectorType       "Straight" ;
        gpml:graphId             "cd670" ;
        gpml:hasPoint            <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/cd670/Point/ce9e773ec52ec66a099053cc62abee88> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/cd670/Point/e635f07e70e6bd96a540d7ece4427d6e> ;
        gpml:hasPublicationXref  <https://identifiers.org/pubmed/28013292> ;
        gpml:lineStyle           "Broken" ;
        gpml:lineThickness       "1.0"^^xsd:double ;
        gpml:zorder              "33001"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Comment/660b4f8d68447152cc1737e2ddedfb90>
        rdf:type          gpml:Comment ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/d59ed> ;
        gpml:commentText  "Chromosome 1: 65,419-71,585" .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/id63d77999/Point/be665ddb9705bc52976a45d159113bf3>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5345_r134459> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/id63d77999> ;
        gpml:graphRef     "ac42d" ;
        gpml:relX         "1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "2897.878894605742"^^xsd:double ;
        gpml:y            "1205.630589244151"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/cdf04/Point/a392acd52d41bc4d0916d9c5cd96bf13>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5345_r134459> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/cdf04> ;
        gpml:graphRef     "dcdb3" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "792.7369964105261"^^xsd:double ;
        gpml:y            "764.0317347610071"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Shape/e7c1d>
        rdf:type             gpml:shape ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5345_r134459> ;
        gpml:align           "Center" ;
        gpml:centerX         "525.3030100252355"^^xsd:double ;
        gpml:centerY         "1199.7419761448753"^^xsd:double ;
        gpml:color           "c0c0c0" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "e7c1d" ;
        gpml:height          "108.4277626793073"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "3.0"^^xsd:double ;
        gpml:shape           "0.0"^^xsd:double ;
        gpml:shapeType       "Mitochondria" ;
        gpml:textlabel       "" ;
        gpml:valign          "Middle" ;
        gpml:width           "212.1751105494081"^^xsd:double ;
        gpml:zorder          "33007"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Shape/d323b>
        rdf:type             gpml:shape ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5345_r134459> ;
        gpml:align           "Center" ;
        gpml:centerX         "943.2736737525244"^^xsd:double ;
        gpml:centerY         "1493.4148749196638"^^xsd:double ;
        gpml:color           "c0c0c0" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "d323b" ;
        gpml:height          "107.07526267930825"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "3.0"^^xsd:double ;
        gpml:shape           "0.0"^^xsd:double ;
        gpml:shapeType       "Mitochondria" ;
        gpml:textlabel       "" ;
        gpml:valign          "Middle" ;
        gpml:width           "206.09177721607443"^^xsd:double ;
        gpml:zorder          "33009"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/f80d7>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5345_r134459> ;
        gpml:align           "Center" ;
        gpml:centerX         "1933.599887964148"^^xsd:double ;
        gpml:centerY         "413.94179644884576"^^xsd:double ;
        gpml:color           "ff" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "f80d7" ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "UDP-galactose" ;
        gpml:type            "Metabolite" ;
        gpml:valign          "Middle" ;
        gpml:width           "90.0"^^xsd:double ;
        gpml:xrefDataSource  "HMDB" ;
        gpml:xrefId          "HMDB0000302" ;
        gpml:zorder          "33126"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/f5e12/Point/e3ddace8e51c543ec99017404c485ac3>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5345_r134459> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/f5e12> ;
        gpml:graphRef     "d371a" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "1786.0622303648593"^^xsd:double ;
        gpml:y            "1076.0136751595667"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/d909c>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Group/e5817> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459> ;
        gpml:align           "Center" ;
        gpml:centerX         "886.0622303648587"^^xsd:double ;
        gpml:centerY         "1113.513675159567"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "d909c" ;
        gpml:groupRef        "d8018" ;
        gpml:height          "24.999999999999936"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "COMMD1" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "89.99999999999999"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000173163" ;
        gpml:zorder          "33015"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/fa364>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5345_r134459> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Group/e5817> ;
        gpml:align           "Center" ;
        gpml:centerX         "886.0622303648587"^^xsd:double ;
        gpml:centerY         "1313.5136751595664"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "fa364" ;
        gpml:groupRef        "d8018" ;
        gpml:height          "24.999999999999936"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "MEPCE" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "89.99999999999999"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000146834" ;
        gpml:zorder          "33035"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Label/d3e76>
        rdf:type             gpml:Label ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5345_r134459> ;
        gpml:align           "Center" ;
        gpml:centerX         "524.4105363441474"^^xsd:double ;
        gpml:centerY         "1382.5736411120913"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "d3e76" ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:href            "" ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "None" ;
        gpml:textlabel       "ribosomal large subunit assembly \n" ;
        gpml:valign          "Middle" ;
        gpml:width           "199.99999999999955"^^xsd:double ;
        gpml:zorder          "33010"^^xsd:long .

<https://identifiers.org/pubmed/17212986>
        rdf:type          gpml:PublicationXref ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/f4409> ;
        gpml:database     "Pubmed" ;
        gpml:id           "17212986" .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/ab8be>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5345_r134459> ;
        gpml:align           "Center" ;
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        gpml:centerY         "347.6491228070183"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "ab8be" ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "SCNN1D" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "90.0"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000162572" ;
        gpml:zorder          "33095"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/idcbd348a6>
        rdf:type                 gpml:Interaction ;
        dcterms:isPartOf         <http://rdf.wikipathways.org/Pathway/WP5345_r134459> ;
        gpml:biopaxRef           "c77" ;
        gpml:color               "0" ;
        gpml:connectorType       "Straight" ;
        gpml:graphId             "idcbd348a6" ;
        gpml:hasPoint            <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/idcbd348a6/Point/47892db9c36e660fc38bd4f9bdb1a266> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/idcbd348a6/Point/a387153ecbb09e1e1be7cebb7e730bb5> ;
        gpml:hasPublicationXref  <https://identifiers.org/pubmed/36419485> ;
        gpml:lineStyle           "Solid" ;
        gpml:lineThickness       "1.0"^^xsd:double ;
        gpml:zorder              "12288"^^xsd:long .

<https://identifiers.org/pubmed/33603070>
        rdf:type          gpml:PublicationXref ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/id5bba33ca> ;
        gpml:database     "Pubmed" ;
        gpml:id           "33603070" .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/idcca0f687>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP5345_r134459> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "idcca0f687" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/idcca0f687/Point/bf59eecfe5956b2eda2b525cb8a05617> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/idcca0f687/Point/ac156fcf6d52b7a479347e1aefcd5581> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/aacd0/Point/97e28d59512080ae4890e7c7bef1c3eb>
        rdf:type          gpml:Point ;
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        gpml:graphRef     "d2730" ;
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/idf7221a2>
        rdf:type                 gpml:Interaction ;
        dcterms:isPartOf         <http://rdf.wikipathways.org/Pathway/WP5345_r134459> ;
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        gpml:color               "0" ;
        gpml:connectorType       "Straight" ;
        gpml:graphId             "idf7221a2" ;
        gpml:hasPoint            <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/idf7221a2/Point/5edc9308e651a83869d6b052b2255a0a> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/idf7221a2/Point/120b26b3a316b7e288c6f06858769414> ;
        gpml:hasPublicationXref  <https://identifiers.org/pubmed/23665105> ;
        gpml:lineStyle           "Solid" ;
        gpml:lineThickness       "1.0"^^xsd:double ;
        gpml:zorder              "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/db19f/Point/f27a14429e3f425bcf5bea5f9d6285b1>
        rdf:type          gpml:Point ;
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        gpml:graphRef     "bc77e" ;
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/e50a0/Point/7328bd1e9f8709580077cc0bb175f88>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5345_r134459> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/e50a0> ;
        gpml:graphRef     "baff6" ;
        gpml:relX         "-1.0"^^xsd:double ;
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/id6b05f823/Anchor/d22d3>
        rdf:type          gpml:Anchor ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5345_r134459> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/id6b05f823> ;
        gpml:graphId      "d22d3" ;
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        gpml:shape        "None" .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/id1ec6cf09/Point/286bdf29084ea006b9ff877bbbe856f3>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5345_r134459> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/id1ec6cf09> ;
        gpml:graphRef     "d9e52" ;
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/id7e217d2c>
        rdf:type                 gpml:Interaction ;
        dcterms:isPartOf         <http://rdf.wikipathways.org/Pathway/WP5345_r134459> ;
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        gpml:color               "0" ;
        gpml:connectorType       "Straight" ;
        gpml:graphId             "id7e217d2c" ;
        gpml:hasPoint            <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/id7e217d2c/Point/16162b4db425556f8a23aa0f848040ef> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/id7e217d2c/Point/d1fbc04f39fc602c1a7238962e77b1da> ;
        gpml:hasPublicationXref  <https://identifiers.org/pubmed/27322068> ;
        gpml:lineStyle           "Solid" ;
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        gpml:xrefDataSource      "Rhea" ;
        gpml:xrefId              "68328" ;
        gpml:zorder              "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/cd0d3/Point/b751a96fb41b6f4b620fc3628b98679b>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5345_r134459> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/cd0d3> ;
        gpml:graphRef     "e5817" ;
        gpml:relX         "0.0"^^xsd:double ;
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        gpml:x            "886.0622303648586"^^xsd:double ;
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/dfc24/Point/9f1c3cdf618004363052a0914dd207d>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5345_r134459> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/dfc24> ;
        gpml:graphRef     "abd37" ;
        gpml:relX         "0.0"^^xsd:double ;
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        gpml:x            "1606.062230364859"^^xsd:double ;
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/d9bbb/Point/f16ec6e669d2f26e669a77b3bff76f5f>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5345_r134459> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/d9bbb> ;
        gpml:graphRef     "ead89" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "2419.2876336351915"^^xsd:double ;
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/pub/dd0>
        rdf:type          gpml:PublicationXref ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/cd0d3> ;
        gpml:id           "" .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/ef2fd/Anchor/dc3cd>
        rdf:type          gpml:Anchor ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5345_r134459> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/ef2fd> ;
        gpml:graphId      "dc3cd" ;
        gpml:position     "0.46685868187468105"^^xsd:double ;
        gpml:shape        "None" .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/d3555>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5345_r134459> ;
        gpml:align           "Center" ;
        gpml:centerX         "1492.7454031338673"^^xsd:double ;
        gpml:centerY         "1175.3740282024205"^^xsd:double ;
        gpml:color           "14961e" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Bold" ;
        gpml:graphId         "d3555" ;
        gpml:height          "24.75"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "RoundedRectangle" ;
        gpml:textlabel       "Mitotic G2-G2/M phases" ;
        gpml:type            "Pathway" ;
        gpml:valign          "Middle" ;
        gpml:width           "159.25"^^xsd:double ;
        gpml:xrefDataSource  "WikiPathways" ;
        gpml:xrefId          "WP1859" ;
        gpml:zorder          "33036"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/f1f5a>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5345_r134459> ;
        gpml:align           "Center" ;
        gpml:centerX         "796.0622303648586"^^xsd:double ;
        gpml:centerY         "1063.513675159567"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "f1f5a" ;
        gpml:hasComment      <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Comment/765efb202c3ea3f19778b1e0c07b9cae> ;
        gpml:height          "24.999999999999936"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "VWA1" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "89.99999999999999"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000179403" ;
        gpml:zorder          "33048"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/dcdfd>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP5345_r134459> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "dcdfd" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/dcdfd/Point/1c60a4ac54813e0b822f45d2b5ecb70b> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/dcdfd/Point/b1552b5c0cacf0dc36ddf328e0c0c2c3> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "32981"^^xsd:long .

<https://identifiers.org/pubmed/23386276>
        rdf:type          gpml:PublicationXref ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/ff5dc> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/be354> ;
        gpml:database     "Pubmed" ;
        gpml:id           "23386276" .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/efe12>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5345_r134459> ;
        gpml:align           "Center" ;
        gpml:centerX         "3128.3567251462005"^^xsd:double ;
        gpml:centerY         "992.6783625730995"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "efe12" ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "CD160" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "90.0"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000117281" ;
        gpml:zorder          "32768"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/ed25c/Anchor/e03bc>
        rdf:type          gpml:Anchor ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5345_r134459> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/ed25c> ;
        gpml:graphId      "e03bc" ;
        gpml:position     "0.4"^^xsd:double ;
        gpml:shape        "None" .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/bd8d4/Point/dd8334cd1d031af5353fe7f83a97b48>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5345_r134459> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/bd8d4> ;
        gpml:graphRef     "c71c6" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "2055.646691845528"^^xsd:double ;
        gpml:y            "1152.8572048791634"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Label/d7d05>
        rdf:type             gpml:Label ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5345_r134459> ;
        gpml:align           "Center" ;
        gpml:centerX         "345.3254655402164"^^xsd:double ;
        gpml:centerY         "1117.4472993093889"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "d7d05" ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:href            "" ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "None" ;
        gpml:textlabel       "Unknown\n" ;
        gpml:valign          "Middle" ;
        gpml:width           "90.0"^^xsd:double ;
        gpml:zorder          "33084"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/aa3e7>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5345_r134459> ;
        gpml:align           "Center" ;
        gpml:centerX         "386.01988950390125"^^xsd:double ;
        gpml:centerY         "432.02265435146376"^^xsd:double ;
        gpml:color           "14961e" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Bold" ;
        gpml:graphId         "aa3e7" ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "RoundedRectangle" ;
        gpml:textlabel       "Olfactory receptor activity " ;
        gpml:type            "Pathway" ;
        gpml:valign          "Middle" ;
        gpml:width           "216.06071911699814"^^xsd:double ;
        gpml:xrefDataSource  "WikiPathways" ;
        gpml:xrefId          "WP3608" ;
        gpml:zorder          "32839"^^xsd:long .

<https://identifiers.org/pubmed/33177874>
        rdf:type          gpml:PublicationXref ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/bd8d4> ;
        gpml:database     "Pubmed" ;
        gpml:id           "33177874" .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/b97c4>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5345_r134459> ;
        gpml:align           "Center" ;
        gpml:centerX         "1328.0964912280742"^^xsd:double ;
        gpml:centerY         "347.64912280701833"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "b97c4" ;
        gpml:height          "25.000000000000004"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "RNF223" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "90.00000000000026"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000237330" ;
        gpml:zorder          "32789"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Comment/91be8285fefd082825e5b98baecdd915>
        rdf:type          gpml:Comment ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/eed1a> ;
        gpml:commentText  "RS:Chromosome 1:187,891-187,958" .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/c793a>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5345_r134459> ;
        gpml:align           "Center" ;
        gpml:centerX         "2596.0622303648584"^^xsd:double ;
        gpml:centerY         "1063.5136751595667"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "c793a" ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "RER1" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "90.0"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000157916" ;
        gpml:zorder          "32971"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Label/d9e52>
        rdf:type             gpml:Label ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5345_r134459> ;
        gpml:align           "Center" ;
        gpml:centerX         "1151.304256334452"^^xsd:double ;
        gpml:centerY         "576.2654790841598"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "d9e52" ;
        gpml:height          "39.23147023086267"^^xsd:double ;
        gpml:href            "" ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "None" ;
        gpml:textlabel       "Activation of\ninnate immunity" ;
        gpml:valign          "Middle" ;
        gpml:width           "110.6136087484812"^^xsd:double ;
        gpml:zorder          "28672"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Label/e5bd1>
        rdf:type             gpml:Label ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5345_r134459> ;
        gpml:align           "Center" ;
        gpml:centerX         "692.9525681490669"^^xsd:double ;
        gpml:centerY         "1138.3343960614268"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "e5bd1" ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:href            "" ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "None" ;
        gpml:textlabel       "encodes a component of \nthe extracellular matrix " ;
        gpml:valign          "Middle" ;
        gpml:width           "155.66666666666652"^^xsd:double ;
        gpml:zorder          "28672"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/c8fe1/Point/62e3589c3f5eaec2b73e219ad2459fbc>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5345_r134459> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/c8fe1> ;
        gpml:graphRef     "ec349" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "2321.5889925726124"^^xsd:double ;
        gpml:y            "665.1147674520357"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/a409e/Point/e3a80e7407c79eb519045f7b297af109>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5345_r134459> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/a409e> ;
        gpml:graphRef     "ec8f2" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "1156.0622303648588"^^xsd:double ;
        gpml:y            "1076.013675159567"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/cb115>
        rdf:type                 gpml:DataNode ;
        dcterms:isPartOf         <http://rdf.wikipathways.org/Pathway/WP5345_r134459> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Group/e5817> ;
        gpml:align               "Center" ;
        gpml:biopaxRef           "c64" ;
        gpml:centerX             "886.0622303648587"^^xsd:double ;
        gpml:centerY             "1063.513675159567"^^xsd:double ;
        gpml:color               "0" ;
        gpml:fillColor           "ffffff" ;
        gpml:fontDecoration      "Normal" ;
        gpml:fontName            "Arial" ;
        gpml:fontSize            "12.0"^^xsd:double ;
        gpml:fontStrikethru      "Normal" ;
        gpml:fontStyle           "Normal" ;
        gpml:fontWeight          "Normal" ;
        gpml:graphId             "cb115" ;
        gpml:groupRef            "d8018" ;
        gpml:hasPublicationXref  <http://rdf.wikipathways.org/Pathway/WP5345_r134459/pub/c64> ;
        gpml:height              "24.999999999999936"^^xsd:double ;
        gpml:lineStyle           "Solid" ;
        gpml:lineThickness       "1.0"^^xsd:double ;
        gpml:shapeType           "Rectangle" ;
        gpml:textlabel           "TGFB1\n" ;
        gpml:type                "GeneProduct" ;
        gpml:valign              "Middle" ;
        gpml:width               "89.99999999999999"^^xsd:double ;
        gpml:xrefDataSource      "Ensembl" ;
        gpml:xrefId              "ENSG00000105329" ;
        gpml:zorder              "33029"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/bee81>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5345_r134459> ;
        gpml:align           "Center" ;
        gpml:centerX         "1778.0964912280756"^^xsd:double ;
        gpml:centerY         "347.6491228070182"^^xsd:double ;
        gpml:color           "9900cc" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "bee81" ;
        gpml:hasComment      <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Comment/b1239b80912aa9852e1d0f584208fbb3> ;
        gpml:height          "25.000000000000004"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "MIR200B" ;
        gpml:type            "Rna" ;
        gpml:valign          "Middle" ;
        gpml:width           "90.00000000000026"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000207730" ;
        gpml:zorder          "32786"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/ff5dc>
        rdf:type                 gpml:Interaction ;
        dcterms:isPartOf         <http://rdf.wikipathways.org/Pathway/WP5345_r134459> ;
        gpml:biopaxRef           "f55" ;
        gpml:color               "0" ;
        gpml:connectorType       "Straight" ;
        gpml:graphId             "ff5dc" ;
        gpml:hasPoint            <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/ff5dc/Point/dcdc6873d950385702d09ced2f9ffdae> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/ff5dc/Point/27957f48e24fef11ec7f771ee2a0bee9> ;
        gpml:hasPublicationXref  <https://identifiers.org/pubmed/23386276> ;
        gpml:lineStyle           "Solid" ;
        gpml:lineThickness       "1.0"^^xsd:double ;
        gpml:zorder              "33074"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/ecf1c/Point/1f9fffef059f3f24ac74c01aeb9bbdd2>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5345_r134459> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/ecf1c> ;
        gpml:graphRef     "bc0bd" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "1741.6291650147637"^^xsd:double ;
        gpml:y            "1375.8673741583682"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/ec101>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5345_r134459> ;
        gpml:align           "Center" ;
        gpml:centerX         "158.09649122807073"^^xsd:double ;
        gpml:centerY         "347.6491228070182"^^xsd:double ;
        gpml:color           "9900cc" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "ec101" ;
        gpml:hasComment      <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Comment/6f3b272c70582ce4d534fcd0b101e51d> ;
        gpml:height          "25.000000000000004"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "MIR1302-2" ;
        gpml:type            "Rna" ;
        gpml:valign          "Middle" ;
        gpml:width           "90.0000000000002"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000284332" ;
        gpml:zorder          "32808"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/ac1a7>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5345_r134459> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Group/ebcb4> ;
        gpml:align           "Center" ;
        gpml:centerX         "2685.3320894189233"^^xsd:double ;
        gpml:centerY         "696.1854093996109"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "ac1a7" ;
        gpml:groupRef        "d5c9c" ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "INTS13\n" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "90.0"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000064102" ;
        gpml:zorder          "33105"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/dab5a>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP5345_r134459> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "dab5a" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/dab5a/Point/38d03f8d640090ac518e5b9bd78a7831> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/dab5a/Point/3e623da4d810a8bb273fe6424fbaeda> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "33000"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/eda15>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5345_r134459> ;
        gpml:align           "Center" ;
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        gpml:centerY         "1288.4768659843965"^^xsd:double ;
        gpml:color           "14961e" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Bold" ;
        gpml:graphId         "eda15" ;
        gpml:height          "36.25"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "RoundedRectangle" ;
        gpml:textlabel       "RNA polymerase II transcribes snRNA genes " ;
        gpml:type            "Pathway" ;
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        gpml:xrefDataSource  "WikiPathways" ;
        gpml:xrefId          "WP3827" ;
        gpml:zorder          "33030"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/f64d4>
        rdf:type                 gpml:Interaction ;
        dcterms:isPartOf         <http://rdf.wikipathways.org/Pathway/WP5345_r134459> ;
        gpml:biopaxRef           "ce6" ;
        gpml:color               "0" ;
        gpml:connectorType       "Straight" ;
        gpml:graphId             "f64d4" ;
        gpml:hasPoint            <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/f64d4/Point/e3162c4766e5e58c83a673f34a69adbf> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/f64d4/Point/3fadf1def07643db0bcae2f8853ea4c3> ;
        gpml:hasPublicationXref  <https://identifiers.org/pubmed/28011644> ;
        gpml:lineStyle           "Solid" ;
        gpml:lineThickness       "1.0"^^xsd:double ;
        gpml:zorder              "33066"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/id5bba33ca/Point/487672593da285da8e7ebc805fa58377>
        rdf:type          gpml:Point ;
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/idcca0f687/Point/ac156fcf6d52b7a479347e1aefcd5581>
        rdf:type          gpml:Point ;
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        gpml:graphRef     "b97c4" ;
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        gpml:relY         "1.0"^^xsd:double ;
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/ede89>
        rdf:type             gpml:DataNode ;
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        gpml:align           "Center" ;
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        gpml:fontWeight      "Normal" ;
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        gpml:groupRef        "d7db6" ;
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        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "IFIH1" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "90.0"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000115267" ;
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Label/ec247>
        rdf:type             gpml:Label ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5345_r134459> ;
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        gpml:fontDecoration  "Normal" ;
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        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
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        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
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        gpml:textlabel       "Decrease stability\nof the leptin mRNA" ;
        gpml:valign          "Middle" ;
        gpml:width           "127.90816326530614"^^xsd:double ;
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/dd7a4/Point/710f88eda7e56e31c9ae87fa155d7ca6>
        rdf:type          gpml:Point ;
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        gpml:graphRef     "a29d4" ;
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/b0e1f>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5345_r134459> ;
        gpml:align           "Center" ;
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        gpml:color           "9900cc" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
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        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "b0e1f" ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "MIR6726" ;
        gpml:type            "Rna" ;
        gpml:valign          "Middle" ;
        gpml:width           "90.0"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000278073" ;
        gpml:zorder          "32768"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/id65c177c9>
        rdf:type                 gpml:Interaction ;
        dcterms:isPartOf         <http://rdf.wikipathways.org/Pathway/WP5345_r134459> ;
        gpml:biopaxRef           "a21" ;
        gpml:color               "0" ;
        gpml:connectorType       "Straight" ;
        gpml:graphId             "id65c177c9" ;
        gpml:hasPoint            <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/id65c177c9/Point/656b4707c7f2f45c36b9df1abf26663b> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/id65c177c9/Point/55240aee60476aaf6538905f5779061c> ;
        gpml:hasPublicationXref  <https://identifiers.org/pubmed/18644345> ;
        gpml:lineStyle           "Solid" ;
        gpml:lineThickness       "1.0"^^xsd:double ;
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/a409e/Point/1ceb0934044ed15d2448f2e2f8b5a625>
        rdf:type          gpml:Point ;
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/d9d4a>
        rdf:type             gpml:DataNode ;
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        gpml:align           "Center" ;
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        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
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        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "d9d4a" ;
        gpml:groupRef        "dad9b" ;
        gpml:hasComment      <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Comment/95bad647a77955b5be70ec962f515048> ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
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        gpml:shapeType       "Rectangle" ;
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        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "90.0"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
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<https://identifiers.org/pubmed/12501247>
        rdf:type          gpml:PublicationXref ;
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        gpml:database     "Pubmed" ;
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/ebe89>
        rdf:type             gpml:DataNode ;
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        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "ebe89" ;
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        gpml:lineStyle       "Solid" ;
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        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
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        gpml:xrefDataSource  "Ensembl" ;
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/b976d>
        rdf:type             gpml:DataNode ;
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        gpml:align           "Center" ;
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        gpml:fontDecoration  "Normal" ;
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        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "b976d" ;
        gpml:groupRef        "e9908" ;
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        gpml:textlabel       "PEX2" ;
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        gpml:valign          "Middle" ;
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        gpml:xrefDataSource  "Entrez Gene" ;
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/bdc26>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP5345_r134459> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "bdc26" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/bdc26/Point/859603b0d97080c2e0505bd01805e480> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/bdc26/Point/3b88190667d6645e8a2e1a2baabb41d4> ;
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<https://identifiers.org/pubmed/18216018>
        rdf:type          gpml:PublicationXref ;
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/id48119db4/Point/139a6ccd89e3d6af9499cf9817e29b6f>
        rdf:type          gpml:Point ;
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/b2fa4>
        rdf:type             gpml:DataNode ;
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/id11c8c4b1/Point/f93ed51351ee80ec16a3d974169d2f7a>
        rdf:type          gpml:Point ;
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/f5e12/Point/deb057d0dc85d9cffe90b73be3a645ff>
        rdf:type          gpml:Point ;
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/b302b/Point/9032752900f9db0f4a74383fa542374e>
        rdf:type          gpml:Point ;
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/c6675/Point/eb176171b9c1ffb130be4e738c871a6b>
        rdf:type          gpml:Point ;
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/e33b0>
        rdf:type             gpml:DataNode ;
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        gpml:fontWeight      "Normal" ;
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        gpml:lineThickness       "1.0"^^xsd:double ;
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/b71fd>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Group/e5817> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459> ;
        gpml:align           "Center" ;
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        gpml:fontName        "Arial" ;
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        gpml:fontStyle       "Normal" ;
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        gpml:graphId         "b71fd" ;
        gpml:groupRef        "d8018" ;
        gpml:height          "24.999999999999936"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "METTL14 " ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "89.99999999999999"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000145388" ;
        gpml:zorder          "33044"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/b58bd/Point/5ad0f85e5e4c0966d756509bcf0cc386>
        rdf:type          gpml:Point ;
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        gpml:graphRef     "a7973" ;
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        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "2588.0964912280765"^^xsd:double ;
        gpml:y            "360.1491228070183"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Group/c646f>
        rdf:type          gpml:Group ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5345_r134459> ;
        gpml:graphId      "c646f" ;
        gpml:groupId      "c9b29" ;
        gpml:style        "Group" .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/ad7ae/Point/57f14fcdd506ca8d6e8b22de89eda141>
        rdf:type          gpml:Point ;
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        gpml:graphRef     "ee6e4" ;
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/id955364ec/Point/516873610703e3182bf645ec4b68a39e>
        rdf:type          gpml:Point ;
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        gpml:graphRef     "e3d25" ;
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        gpml:x            "1418.0964912280742"^^xsd:double ;
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/b82fd>
        rdf:type                 gpml:Interaction ;
        dcterms:isPartOf         <http://rdf.wikipathways.org/Pathway/WP5345_r134459> ;
        gpml:biopaxRef           "a06" ;
        gpml:color               "0" ;
        gpml:connectorType       "Straight" ;
        gpml:graphId             "b82fd" ;
        gpml:hasPoint            <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/b82fd/Point/4ec30aedcaf8fc15c11c39a9bcec6007> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/b82fd/Point/666f7bb88b4ed87d9cca63b8754df210> ;
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        gpml:lineStyle           "Solid" ;
        gpml:lineThickness       "1.0"^^xsd:double ;
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Label/c7de8>
        rdf:type             gpml:Label ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5345_r134459> ;
        gpml:align           "Center" ;
        gpml:centerX         "641.6789112239915"^^xsd:double ;
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        gpml:color           "0" ;
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        gpml:fontName        "Arial" ;
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        gpml:fontWeight      "Normal" ;
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        gpml:height          "25.0"^^xsd:double ;
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        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "None" ;
        gpml:textlabel       "DNA-templated transcription" ;
        gpml:valign          "Middle" ;
        gpml:width           "172.9192338290734"^^xsd:double ;
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/dd7a4/Point/ca50552a71f8464e339b89db101345d1>
        rdf:type          gpml:Point ;
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        gpml:graphRef     "c271a" ;
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/c1bb9>
        rdf:type             gpml:DataNode ;
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        gpml:type            "Rna" ;
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        gpml:xrefDataSource  "Ensembl" ;
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/d9bbb/Point/3c76226d8f5c65216944b93aafd7b741>
        rdf:type          gpml:Point ;
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        gpml:graphRef     "cbd5b" ;
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Label/e9d5d>
        rdf:type             gpml:Label ;
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        gpml:fontWeight      "Normal" ;
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        gpml:textlabel       "HDAC p53/TP53" ;
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        gpml:width           "96.94805194805204"^^xsd:double ;
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/idcb599d73/Point/8ca3ff53bd86da17111fc88ef0ec3507>
        rdf:type          gpml:Point ;
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        gpml:graphRef     "e6b7d" ;
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/b4f9a/Point/27d9da6a62e0959145c1637cf5b1ee33>
        rdf:type          gpml:Point ;
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        gpml:graphRef     "e0407" ;
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/d6ae0/Point/2076a7455d648554358d82e4d7d298f0>
        rdf:type          gpml:Point ;
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/ead89>
        rdf:type             gpml:DataNode ;
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        gpml:align           "Center" ;
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        gpml:color           "0" ;
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        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "ead89" ;
        gpml:groupRef        "b53a8" ;
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        gpml:textlabel       "SMAD2" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
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        gpml:xrefDataSource  "HGNC" ;
        gpml:xrefId          "SMAD2" ;
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/da497/Point/9f7a3e579a95a8ca15263fad86444f6d>
        rdf:type          gpml:Point ;
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        gpml:graphRef     "b703c" ;
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/bd749>
        rdf:type             gpml:DataNode ;
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        gpml:textlabel       "DLL1" ;
        gpml:type            "Protein" ;
        gpml:valign          "Middle" ;
        gpml:width           "90.0"^^xsd:double ;
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        gpml:xrefId          "ENSG00000198719" ;
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Comment/b1239b80912aa9852e1d0f584208fbb3>
        rdf:type          gpml:Comment ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/bee81> ;
        gpml:commentText  "ncRNA (MiRNA)" .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Comment/46f99d42080da22d4c18e05e617d7016>
        rdf:type          gpml:Comment ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/ee8ac> ;
        gpml:commentText  "small ribosomal subunit" .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/idcb599d73>
        rdf:type                 gpml:Interaction ;
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/c271a>
        rdf:type             gpml:DataNode ;
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/ca3b4>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5345_r134459> ;
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        gpml:fontWeight      "Normal" ;
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        gpml:type            "GeneProduct" ;
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Label/d0841>
        rdf:type             gpml:Label ;
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        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
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        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "None" ;
        gpml:textlabel       "p53/TP53 apoptosis" ;
        gpml:valign          "Middle" ;
        gpml:width           "127.25108225108234"^^xsd:double ;
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/e8316>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5345_r134459> ;
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        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "e8316" ;
        gpml:height          "25.000000000000004"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "MIR429" ;
        gpml:type            "Rna" ;
        gpml:valign          "Middle" ;
        gpml:width           "90.0000000000002"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000198976" ;
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Group/f323e>
        rdf:type          gpml:Group ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5345_r134459> ;
        gpml:graphId      "f323e" ;
        gpml:groupId      "acb8e" ;
        gpml:style        "Complex" .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/id6b05f823>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP5345_r134459> ;
        gpml:color          "0" ;
        gpml:connectorType  "Elbow" ;
        gpml:graphId        "id6b05f823" ;
        gpml:hasAnchor      <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/id6b05f823/Anchor/d22d3> ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/id6b05f823/Point/68921f8f615f1f42dfcb73ef5b75ce9e> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/id6b05f823/Point/c063d1e0ee100dd590fe3820a804fd60> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/b9bcc/Point/b71880e08b46959fa7d93bd6c22a41dc>
        rdf:type          gpml:Point ;
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        gpml:graphRef     "dc3cd" ;
        gpml:relX         "0.0"^^xsd:double ;
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/fcf65>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5345_r134459> ;
        gpml:align           "Center" ;
        gpml:centerX         "2236.0622303648584"^^xsd:double ;
        gpml:centerY         "1063.5136751595667"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "fcf65" ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "PRKCZ" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "90.0"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000067606" ;
        gpml:zorder          "32972"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/bfcf1>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Group/a72b9> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459> ;
        gpml:align           "Center" ;
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        gpml:centerY         "1257.023180269568"^^xsd:double ;
        gpml:color           "14961e" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
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        gpml:fontStrikethru  "Normal" ;
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        gpml:fontWeight      "Bold" ;
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        gpml:groupRef        "d2150" ;
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        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "RoundedRectangle" ;
        gpml:textlabel       "Regulation of IGF \ntransport and uptake by \nIGF binding proteins\n" ;
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        gpml:valign          "Middle" ;
        gpml:width           "166.0"^^xsd:double ;
        gpml:xrefDataSource  "WikiPathways" ;
        gpml:xrefId          "WP2799" ;
        gpml:zorder          "32768"^^xsd:long .

<https://identifiers.org/pubmed/28082677>
        rdf:type          gpml:PublicationXref ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/b58bd> ;
        gpml:database     "Pubmed" ;
        gpml:id           "28082677" .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/a68f8>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP5345_r134459> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "a68f8" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/a68f8/Point/837fbb4c49d4ea36c04554afd80f3433> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/a68f8/Point/c46e86389e58d18d7f63b74dd307f6a0> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "32913"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/id82ba66ef>
        rdf:type                 gpml:Interaction ;
        dcterms:isPartOf         <http://rdf.wikipathways.org/Pathway/WP5345_r134459> ;
        gpml:biopaxRef           "e31" ;
        gpml:color               "0" ;
        gpml:connectorType       "Straight" ;
        gpml:graphId             "id82ba66ef" ;
        gpml:hasPoint            <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/id82ba66ef/Point/b32473ce3a15e4b373abaf33051c2f17> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/id82ba66ef/Point/918f861f1c3347d20427d9a2c0367ccc> ;
        gpml:hasPublicationXref  <https://identifiers.org/pubmed/36578782> ;
        gpml:lineStyle           "Solid" ;
        gpml:lineThickness       "1.0"^^xsd:double ;
        gpml:zorder              "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/idcbd348a6/Point/47892db9c36e660fc38bd4f9bdb1a266>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5345_r134459> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/idcbd348a6> ;
        gpml:graphRef     "e9c3d" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "968.096491228073"^^xsd:double ;
        gpml:y            "360.14912280701833"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/id3f86f5b7/Point/76adf11deb402d2b365b05dcd0ab2dcd>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5345_r134459> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/id3f86f5b7> ;
        gpml:graphRef     "f323e" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "1243.59432855465"^^xsd:double ;
        gpml:y            "496.2395879036526"^^xsd:double .

<https://identifiers.org/pubmed/22969013>
        rdf:type          gpml:PublicationXref ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/id14d19cb3> ;
        gpml:database     "Pubmed" ;
        gpml:id           "22969013" .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Group/e3720>
        rdf:type          gpml:Group ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5345_r134459> ;
        gpml:groupId      "e3720" ;
        gpml:style        "Group" .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/b58bd>
        rdf:type                 gpml:Interaction ;
        dcterms:isPartOf         <http://rdf.wikipathways.org/Pathway/WP5345_r134459> ;
        gpml:biopaxRef           "ec4" ;
        gpml:color               "0" ;
        gpml:connectorType       "Straight" ;
        gpml:graphId             "b58bd" ;
        gpml:hasPoint            <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/b58bd/Point/5ad0f85e5e4c0966d756509bcf0cc386> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/b58bd/Point/86367a5e416fb84ec91261654f0252b6> ;
        gpml:hasPublicationXref  <https://identifiers.org/pubmed/28082677> ;
        gpml:lineStyle           "Solid" ;
        gpml:lineThickness       "1.0"^^xsd:double ;
        gpml:zorder              "33080"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/b4917>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5345_r134459> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Group/f323e> ;
        gpml:align           "Center" ;
        gpml:centerX         "1243.59432855465"^^xsd:double ;
        gpml:centerY         "520.7395879036526"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "b4917" ;
        gpml:groupRef        "acb8e" ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "LRP4" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "90.0"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000134569" ;
        gpml:zorder          "32768"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Label/a2285>
        rdf:type             gpml:Label ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5345_r134459> ;
        gpml:align           "Center" ;
        gpml:centerX         "1506.7780330892006"^^xsd:double ;
        gpml:centerY         "1131.560213587753"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
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        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "a2285" ;
        gpml:height          "35.56121178141747"^^xsd:double ;
        gpml:href            "" ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "None" ;
        gpml:textlabel       "cytokinesis\napoptosis\n" ;
        gpml:valign          "Middle" ;
        gpml:width           "72.22504072609334"^^xsd:double ;
        gpml:zorder          "33050"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Label/abb62>
        rdf:type             gpml:Label ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5345_r134459> ;
        gpml:align           "Center" ;
        gpml:centerX         "2146.038746790468"^^xsd:double ;
        gpml:centerY         "1136.849422469306"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "abb62" ;
        gpml:height          "27.21410641254716"^^xsd:double ;
        gpml:href            "" ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "None" ;
        gpml:textlabel       "Tonic inhibition" ;
        gpml:valign          "Middle" ;
        gpml:width           "126.12091210759898"^^xsd:double ;
        gpml:zorder          "28672"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/d87af>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5345_r134459> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Group/eb46d> ;
        gpml:align           "Center" ;
        gpml:centerX         "1604.2167662043075"^^xsd:double ;
        gpml:centerY         "1244.6537779415921"^^xsd:double ;
        gpml:color           "14961e" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Bold" ;
        gpml:graphId         "d87af" ;
        gpml:groupRef        "eb0e2" ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "RoundedRectangle" ;
        gpml:textlabel       "Cell cycle" ;
        gpml:type            "Pathway" ;
        gpml:valign          "Middle" ;
        gpml:width           "90.0"^^xsd:double ;
        gpml:xrefDataSource  "WikiPathways" ;
        gpml:xrefId          "WP844" ;
        gpml:zorder          "32978"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/e940e>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP5345_r134459> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "e940e" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/e940e/Point/f5b895b1bc8919bb5d2c9dc67c4a7e23> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/e940e/Point/348e733beea95a7a5b0ce5ce6a5dda19> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "33063"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Comment/6f3b272c70582ce4d534fcd0b101e51d>
        rdf:type          gpml:Comment ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/ec101> ;
        gpml:commentText  "Chromosome 1:30,366-30,503" .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/id16ee34f8>
        rdf:type                 gpml:Interaction ;
        dcterms:isPartOf         <http://rdf.wikipathways.org/Pathway/WP5345_r134459> ;
        gpml:biopaxRef           "d8b" ;
        gpml:color               "0" ;
        gpml:connectorType       "Straight" ;
        gpml:graphId             "id16ee34f8" ;
        gpml:hasPoint            <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/id16ee34f8/Point/2065203a3334a73c2ebf6cf17e2dc3b4> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/id16ee34f8/Point/ca18f2d1a545f5c18bf17fbd4c012009> ;
        gpml:hasPublicationXref  <https://identifiers.org/pubmed/23665105> ;
        gpml:lineStyle           "Solid" ;
        gpml:lineThickness       "1.0"^^xsd:double ;
        gpml:zorder              "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/aee00>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5345_r134459> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Group/ebcb4> ;
        gpml:align           "Center" ;
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        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "aee00" ;
        gpml:groupRef        "d5c9c" ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "INTS10" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "90.0"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000104613" ;
        gpml:zorder          "33114"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/e9c3d>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5345_r134459> ;
        gpml:align           "Center" ;
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        gpml:centerY         "347.64912280701833"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "e9c3d" ;
        gpml:hasComment      <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Comment/740314cc42bb2c05131006870c573fe8> ;
        gpml:height          "25.000000000000004"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "PERM1" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "90.00000000000026"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000187642" ;
        gpml:zorder          "32776"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/b77f6/Point/808f18b7f049cccb20e51f7781217431>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5345_r134459> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/b77f6> ;
        gpml:graphRef     "fc44f" ;
        gpml:relX         "0.5"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "978.6042486403161"^^xsd:double ;
        gpml:y            "1473.1293506173474"^^xsd:double .

<https://identifiers.org/pubmed/36650543>
        rdf:type          gpml:PublicationXref ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/ecd6e> ;
        gpml:database     "Pubmed" ;
        gpml:id           "36650543" .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/id82ba66ef/Point/918f861f1c3347d20427d9a2c0367ccc>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5345_r134459> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/id82ba66ef> ;
        gpml:graphRef     "d083d" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "1688.0964912280756"^^xsd:double ;
        gpml:y            "360.14912280701833"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/fcf96/Point/99649d0460d560e49d26cf1c8914d978>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5345_r134459> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/fcf96> ;
        gpml:graphRef     "f481b" ;
        gpml:relX         "0.5"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "1358.5622303648586"^^xsd:double ;
        gpml:y            "1076.013675159567"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/b651f>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP5345_r134459> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "b651f" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/b651f/Point/e571d135b8fa84c46b7980db0b905784> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/b651f/Point/39a1e35a22a158c7c87504f6e6f5b590> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "32999"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/d56a3>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/b703c>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Label/c71c6>
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<https://identifiers.org/pubmed/18644345>
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<https://identifiers.org/pubmed/28650474>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/f11ff/Point/b63eb8419fffb1fa34e821416f520dba>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/db19f/Point/deb1d14a4b88315e6d83aef22e535ce4>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/fe0e6/Point/a52ba3edd4b491bd12bd7663d00580ae>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/idecdead92>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Comment/838df38bfd4ec7cf067abcd4f7016a9e>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/f19c2>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/iddc2630e8/Point/8aede580e571abbe2daeffe3b52bc571>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/a29d4>
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<https://identifiers.org/pubmed/19587085>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/idf19bf22/Point/5b5bbf60d59d5adf89a11cefd8d707d8>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/fd350>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/bdc26/Point/3b88190667d6645e8a2e1a2baabb41d4>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/cf095>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/db19f>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/a022b/Point/7d23140ac34e46a384f6203ba37581fc>
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<https://identifiers.org/pubmed/18193050>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/pub/d31>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/e9d40>
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        gpml:width           "90.0"^^xsd:double ;
        gpml:xrefDataSource  "Wikidata" ;
        gpml:xrefId          "Q3083814" ;
        gpml:zorder          "32945"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/dd7a4>
        rdf:type                 gpml:Interaction ;
        dcterms:isPartOf         <http://rdf.wikipathways.org/Pathway/WP5345_r134459> ;
        gpml:biopaxRef           "d57" , "c9a" ;
        gpml:color               "0" ;
        gpml:connectorType       "Straight" ;
        gpml:graphId             "dd7a4" ;
        gpml:hasPoint            <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/dd7a4/Point/ca50552a71f8464e339b89db101345d1> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/dd7a4/Point/710f88eda7e56e31c9ae87fa155d7ca6> ;
        gpml:hasPublicationXref  <https://identifiers.org/pubmed/32987154> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/pub/d57> ;
        gpml:lineStyle           "Solid" ;
        gpml:lineThickness       "1.0"^^xsd:double ;
        gpml:zorder              "33003"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/f0278>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5345_r134459> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Group/b48b4> ;
        gpml:align           "Center" ;
        gpml:centerX         "2021.178997876472"^^xsd:double ;
        gpml:centerY         "533.739579415311"^^xsd:double ;
        gpml:color           "14961e" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Bold" ;
        gpml:graphId         "f0278" ;
        gpml:groupRef        "b5518" ;
        gpml:height          "24.53881801233782"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "RoundedRectangle" ;
        gpml:textlabel       "Proinflammatory Gene Expression" ;
        gpml:type            "Pathway" ;
        gpml:valign          "Middle" ;
        gpml:width           "206.33617626154944"^^xsd:double ;
        gpml:xrefDataSource  "WikiPathways" ;
        gpml:xrefId          "WP195" ;
        gpml:zorder          "33106"^^xsd:long .

<https://identifiers.org/pubmed/14726523>
        rdf:type          gpml:PublicationXref ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/c8fe1> ;
        gpml:database     "Pubmed" ;
        gpml:id           "14726523" .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/cc71d>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5345_r134459> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Group/dcdb3> ;
        gpml:align           "Center" ;
        gpml:centerX         "792.7369964105261"^^xsd:double ;
        gpml:centerY         "689.5317347610073"^^xsd:double ;
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        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
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        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "cc71d" ;
        gpml:groupRef        "ee9fc" ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "BTB" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "90.0"^^xsd:double ;
        gpml:xrefDataSource  "" ;
        gpml:xrefId          "" ;
        gpml:zorder          "32989"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/f6ccb>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Group/d0d64> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459> ;
        gpml:align           "Center" ;
        gpml:centerX         "524.4105363441474"^^xsd:double ;
        gpml:centerY         "1326.7459746005827"^^xsd:double ;
        gpml:color           "14961e" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Bold" ;
        gpml:graphId         "f6ccb" ;
        gpml:groupRef        "b9066" ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "RoundedRectangle" ;
        gpml:textlabel       "miR-targeted genes " ;
        gpml:type            "Pathway" ;
        gpml:valign          "Middle" ;
        gpml:width           "191.91666666666708"^^xsd:double ;
        gpml:xrefDataSource  "WikiPathways" ;
        gpml:xrefId          "WP2002" ;
        gpml:zorder          "32768"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/cbd5b>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5345_r134459> ;
        gpml:align           "Center" ;
        gpml:centerX         "2416.0622303648584"^^xsd:double ;
        gpml:centerY         "1063.5136751595667"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "cbd5b" ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "SKI" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "90.0"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000157933" ;
        gpml:zorder          "32974"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/idc6f000bb/Point/54aa78206794b3bcbcb7c8e052acf1b0>
        rdf:type          gpml:Point ;
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        gpml:graphRef     "da437" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "1599.530201342279"^^xsd:double ;
        gpml:y            "492.64643075045774"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/e007f/Point/9c75c794f112d419b1875ff201739a65>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5345_r134459> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/e007f> ;
        gpml:graphRef     "b48b4" ;
        gpml:relX         "0.5"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "2076.7630419418592"^^xsd:double ;
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/da497/Point/34277cbb3391c773d6322a43ebfbccf8>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5345_r134459> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/da497> ;
        gpml:graphRef     "e7c7e" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "75.00542445948474"^^xsd:double ;
        gpml:y            "1112.1788150589668"^^xsd:double .

<https://identifiers.org/pubmed/28013292>
        rdf:type          gpml:PublicationXref ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/cd670> ;
        gpml:database     "Pubmed" ;
        gpml:id           "28013292" .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/a7973>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5345_r134459> ;
        gpml:align           "Center" ;
        gpml:centerX         "2588.0964912280765"^^xsd:double ;
        gpml:centerY         "347.6491228070183"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "a7973" ;
        gpml:height          "24.99999999999999"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "PUSL1" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "90.00000000000001"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000169972" ;
        gpml:zorder          "33094"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/a3240/Point/54d5d7750e11aec4ef4e5392d4149422>
        rdf:type          gpml:Point ;
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        gpml:graphRef     "d3555" ;
        gpml:relX         "-0.5"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "1452.9329031338673"^^xsd:double ;
        gpml:y            "1162.9990282024205"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/ed25c/Point/4b495f4c0453cbef2a9a5abc413ee02e>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5345_r134459> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/ed25c> ;
        gpml:graphRef     "ae930" ;
        gpml:relX         "-1.0"^^xsd:double ;
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        gpml:x            "2905.161627135058"^^xsd:double ;
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/a20a2/Point/92542508f998d7e349eab3e1b5307411>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5345_r134459> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/a20a2> ;
        gpml:graphRef     "b5360" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "2138.096491228076"^^xsd:double ;
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/id82ba66ef/Point/b32473ce3a15e4b373abaf33051c2f17>
        rdf:type          gpml:Point ;
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        gpml:graphRef     "eaadc" ;
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        gpml:x            "1691.8514739060245"^^xsd:double ;
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/id71f6e57f/Point/c4d2ad759ecf56da6b37ee1eea21afee>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5345_r134459> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/id71f6e57f> ;
        gpml:graphRef     "adde5" ;
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/e3d25>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5345_r134459> ;
        gpml:align           "Center" ;
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        gpml:centerY         "347.64912280701833"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "e3d25" ;
        gpml:height          "25.000000000000004"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "C1orf159" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "90.00000000000026"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000131591" ;
        gpml:zorder          "32773"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/ac6c1/Point/1d5e446d88c6b327c87a8a5af132e545>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5345_r134459> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/ac6c1> ;
        gpml:graphRef     "a9efb" ;
        gpml:relX         "0.0"^^xsd:double ;
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Label/f1f19>
        rdf:type             gpml:Label ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5345_r134459> ;
        gpml:align           "Center" ;
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        gpml:centerY         "1246.4050100707552"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "10.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "f1f19" ;
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        gpml:href            "" ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "None" ;
        gpml:textlabel       "actin binding\nzinc and metal ion binding\ntransferase activity" ;
        gpml:valign          "Middle" ;
        gpml:width           "125.07986587534197"^^xsd:double ;
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/dc10f>
        rdf:type                 gpml:Interaction ;
        dcterms:isPartOf         <http://rdf.wikipathways.org/Pathway/WP5345_r134459> ;
        gpml:biopaxRef           "efe" ;
        gpml:color               "0" ;
        gpml:connectorType       "Straight" ;
        gpml:graphId             "dc10f" ;
        gpml:hasPoint            <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/dc10f/Point/2dca465a47fb23b864ac72e66129db43> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/dc10f/Point/4ed405f50ed83210e3dacee11fe897ac> ;
        gpml:hasPublicationXref  <https://identifiers.org/pubmed/36459505> ;
        gpml:lineStyle           "Solid" ;
        gpml:lineThickness       "1.0"^^xsd:double ;
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/b5360>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5345_r134459> ;
        gpml:align           "Center" ;
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        gpml:centerY         "347.6491228070183"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "b5360" ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "C1QTNF12" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "90.0"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000184163" ;
        gpml:zorder          "33122"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/f11ff/Point/da00963f7ea35cff0b11f1bd53dbb137>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5345_r134459> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/f11ff> ;
        gpml:graphRef     "ec915" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "2120.9452891812357"^^xsd:double ;
        gpml:y            "1344.6201596250585"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/dd698>
        rdf:type                 gpml:Interaction ;
        dcterms:isPartOf         <http://rdf.wikipathways.org/Pathway/WP5345_r134459> ;
        gpml:biopaxRef           "f82" , "a8d" ;
        gpml:color               "0" ;
        gpml:connectorType       "Straight" ;
        gpml:graphId             "dd698" ;
        gpml:hasPoint            <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/dd698/Point/92b1b370c00b4fc0b07c3f18af463637> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/dd698/Point/f279c0c441a6fdf3f4b756e96d96e86> ;
        gpml:hasPublicationXref  <https://identifiers.org/pubmed/9162022> , <https://identifiers.org/pubmed/9153189> ;
        gpml:lineStyle           "Solid" ;
        gpml:lineThickness       "1.0"^^xsd:double ;
        gpml:zorder              "33136"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/ceb80>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP5345_r134459> ;
        gpml:color          "0" ;
        gpml:connectorType  "Elbow" ;
        gpml:graphId        "ceb80" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/ceb80/Point/3a085b0d3628fcd687164bec7b62a82> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/ceb80/Point/b7d647cb0653648e878572c4629797a0> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "32922"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/d92b4>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5345_r134459> ;
        gpml:align           "Center" ;
        gpml:centerX         "1696.0622303648593"^^xsd:double ;
        gpml:centerY         "1063.5136751595667"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "d92b4" ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "NADK" ;
        gpml:type            "GeneProduct" ;
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/idb0eb46ba/Point/968757e91fbdf8af9d64ef142ed2c59a>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/e8b71>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Shape/c946e>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/f11ff>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/ecf1c/Anchor/fc9ce>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/iddc2630e8>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/c7f17>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/idf19bf22>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/ac6c1>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/bb14c>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/be354>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/dc10f/Point/4ed405f50ed83210e3dacee11fe897ac>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/id48119db4/Point/35ac40a3f8313ccf59f560d8251d2268>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Comment/f187299841c173e22dce5248cfbe6f0b>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/c1a38>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/eb90a>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/f4409/Point/790b72c2790afe22dd3c74036931bd6d>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Label/b2025>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/e0f21>
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<https://identifiers.org/pubmed/21849507>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/pub/d57>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/b6246>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Label/ee6e4>
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        gpml:textlabel       "Gamma-secretase complex \nassembly" ;
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/ad7ae>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/id1ec6cf09>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/ea148>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/b0920>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/f8faf>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/e940e/Point/348e733beea95a7a5b0ce5ce6a5dda19>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/da497>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Label/a4ff0>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Group/dcdb3>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Group/dbdd8>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/a4a8d>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/cd0d3>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/b1327>
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<https://identifiers.org/pubmed/35217789>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/idd36a2d2>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/ba5a6>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/a94e6>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/ec8f2>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/d86b2>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Comment/8a8d9052a40ceeb021bae17402667acf>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/ef2fd/Point/fd0d9312a9d5e5bf203a70c04fd8e06e>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Comment/e23951c64804037fc387b3113b93ec4e>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Group/ef42d>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/fe0e6/Point/d0a8cc16a4e0228ad8482e4828bc2ad0>
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<https://identifiers.org/pubmed/21474938>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/f6506>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/d2f70>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/ff5dc/Point/dcdc6873d950385702d09ced2f9ffdae>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/a3240/Point/7515af1d84a1f5d6a81ee53d81b7d79b>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/id63d77999>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/d2efd>
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<https://identifiers.org/pubmed/15944293>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Label/bbc4b>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/f4409/Point/d3011306bdbb556d8cde14e5abeb6a62>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/idd36a2d2/Point/a9ae11b97d40ed5e22759c23f4edcfab>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Label/e8d16>
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<https://identifiers.org/pubmed/23761635>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/b6696>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/id379e9c6b/Point/c98adf45c138a865ee2126237726ec11>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/ebe43>
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<https://identifiers.org/pubmed/33727702>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Group/e5817>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/fb1e0>
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<https://identifiers.org/pubmed/25083800>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/id955364ec>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Group/ce665>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Group/a72b9>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/c6675>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/bc0bd>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Group/e54fb>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/b302b>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/d9f1e>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Comment/f5dfd942829e95b492146723a195a56>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/ad7ae/Point/619414fc45473171e6c2f81aa0bfacd6>
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<https://identifiers.org/pubmed/32697989>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/cd0d3/Point/55fe805733d1babd849fcdaaee5e783a>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/f1204>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/fa93d>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/b4f9a/Point/49182b237123fa3dae57a011b5fecb40>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/d59ed>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/be354/Point/ee1016207cbd92ad0e4fbdf079017b28>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Shape/fc20e>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/id21fea3ee/Point/a1b9962d2ab7d3115240a41a93e44eee>
        rdf:type          gpml:Point ;
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<https://identifiers.org/pubmed/29164996>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/e940e/Point/f5b895b1bc8919bb5d2c9dc67c4a7e23>
        rdf:type          gpml:Point ;
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/ddc85/Point/1827a5dcec5aa6ed4bc5db8aa8ed9c8c>
        rdf:type          gpml:Point ;
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/c8fe1>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Group/c5524>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/c9c0f>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/a20a2/Point/415da4573dc77dd10b16b3182e9f157b>
        rdf:type          gpml:Point ;
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        gpml:graphRef     "ab487" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "2140.2668183001647"^^xsd:double ;
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Comment/3e3993f0f6635d0c95976c35d5ed090d>
        rdf:type          gpml:Comment ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/ada65> ;
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/db19f/Anchor/df14a>
        rdf:type          gpml:Anchor ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5345_r134459> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/db19f> ;
        gpml:graphId      "df14a" ;
        gpml:position     "0.4536785506729061"^^xsd:double ;
        gpml:shape        "None" .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/c433b>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5345_r134459> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Group/f44fe> ;
        gpml:align           "Center" ;
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        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "c433b" ;
        gpml:groupRef        "e9908" ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "PEX10" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "90.0"^^xsd:double ;
        gpml:xrefDataSource  "Entrez Gene" ;
        gpml:xrefId          "5192" ;
        gpml:zorder          "32976"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Label/f4ee4>
        rdf:type             gpml:Label ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5345_r134459> ;
        gpml:align           "Center" ;
        gpml:centerX         "1964.8880194251715"^^xsd:double ;
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        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
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        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "f4ee4" ;
        gpml:height          "20.383495326110882"^^xsd:double ;
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        gpml:lineStyle       "Solid" ;
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        gpml:shapeType       "None" ;
        gpml:textlabel       "Membrane component" ;
        gpml:valign          "Middle" ;
        gpml:width           "131.0"^^xsd:double ;
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<https://identifiers.org/pubmed/36713553>
        rdf:type          gpml:PublicationXref ;
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        gpml:database     "Pubmed" ;
        gpml:id           "36713553" .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/idcbd348a6/Point/a387153ecbb09e1e1be7cebb7e730bb5>
        rdf:type          gpml:Point ;
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/ed796>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5345_r134459> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Group/dad9b> ;
        gpml:align           "Center" ;
        gpml:centerX         "976.0622303648587"^^xsd:double ;
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        gpml:fontDecoration  "Normal" ;
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        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "ed796" ;
        gpml:groupRef        "dad9b" ;
        gpml:hasComment      <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Comment/a7087848b25c98d6bb746553f13a8a91> ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "ATAD3A" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "90.0"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000197785" ;
        gpml:zorder          "33034"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/b651f/Point/e571d135b8fa84c46b7980db0b905784>
        rdf:type          gpml:Point ;
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        gpml:graphRef     "e54fb" ;
        gpml:relX         "-0.5"^^xsd:double ;
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        gpml:x            "1345.3307037712684"^^xsd:double ;
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/c9c0f/Point/7c55d2922b1a9f2e6489b767aad604d6>
        rdf:type          gpml:Point ;
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        gpml:graphRef     "fc9ce" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "1696.2290985286936"^^xsd:double ;
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/ada65>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5345_r134459> ;
        gpml:align           "Center" ;
        gpml:centerX         "793.5199995836475"^^xsd:double ;
        gpml:centerY         "844.0947739062508"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "ada65" ;
        gpml:hasComment      <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Comment/3e3993f0f6635d0c95976c35d5ed090d> ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "GRIK2" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "90.0"^^xsd:double ;
        gpml:xrefDataSource  "Entrez Gene" ;
        gpml:xrefId          "2898" ;
        gpml:zorder          "32991"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Group/eb46d>
        rdf:type          gpml:Group ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5345_r134459> ;
        gpml:graphId      "eb46d" ;
        gpml:groupId      "eb0e2" ;
        gpml:style        "Group" .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Comment/9b9fff0fd69ebc9eaca8bde5b22de751>
        rdf:type          gpml:Comment ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/b0920> ;
        gpml:commentText  "RS:Chromosome 1:450,740-451,678" .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/id33030e3>
        rdf:type                 gpml:Interaction ;
        dcterms:isPartOf         <http://rdf.wikipathways.org/Pathway/WP5345_r134459> ;
        gpml:biopaxRef           "b3a" ;
        gpml:color               "0" ;
        gpml:connectorType       "Straight" ;
        gpml:graphId             "id33030e3" ;
        gpml:hasPoint            <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/id33030e3/Point/ee3a4787fb41c028923469f78cae30fe> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/id33030e3/Point/82353ab490b96b17ee850f378acca0a1> ;
        gpml:hasPublicationXref  <https://identifiers.org/pubmed/29559363> ;
        gpml:lineStyle           "Solid" ;
        gpml:lineThickness       "1.0"^^xsd:double ;
        gpml:zorder              "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Comment/a868ae00b38b23da2dd9b879df097028>
        rdf:type          gpml:Comment ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/ebe89> ;
        gpml:commentText  "Ubiquiting-like protein" .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/cec32>
        rdf:type                 gpml:Interaction ;
        dcterms:isPartOf         <http://rdf.wikipathways.org/Pathway/WP5345_r134459> ;
        gpml:biopaxRef           "bf6" ;
        gpml:color               "0" ;
        gpml:connectorType       "Straight" ;
        gpml:graphId             "cec32" ;
        gpml:hasPoint            <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/cec32/Point/685b0be786de0f8b92430e687db6d510> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/cec32/Point/9bf67bd7ce45c4f723df9f62052cc232> ;
        gpml:hasPublicationXref  <https://identifiers.org/pubmed/33328586> ;
        gpml:lineStyle           "Broken" ;
        gpml:lineThickness       "1.0"^^xsd:double ;
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/a5fcb>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Group/c5524> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459> ;
        gpml:align           "Center" ;
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        gpml:color           "ff" ;
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        gpml:graphId         "a5fcb" ;
        gpml:groupRef        "c3fb9" ;
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        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "Diacylglycerol" ;
        gpml:type            "Metabolite" ;
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/a17b1>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Group/d0d64> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459> ;
        gpml:align           "Center" ;
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        gpml:graphId         "a17b1" ;
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        gpml:height          "28.08333333333394"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "RoundedRectangle" ;
        gpml:textlabel       "Mitochondrial translation " ;
        gpml:type            "Pathway" ;
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        gpml:width           "191.91666666666708"^^xsd:double ;
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/dbba7/Point/9f5d4584fc13d6e3c9cc92c403dd8cd2>
        rdf:type          gpml:Point ;
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        gpml:graphRef     "d2efd" ;
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/cec32/Point/685b0be786de0f8b92430e687db6d510>
        rdf:type          gpml:Point ;
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        gpml:graphRef     "a2285" ;
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/c1450>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Group/ab487> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459> ;
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        gpml:fontWeight      "Bold" ;
        gpml:graphId         "c1450" ;
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        gpml:shapeType       "RoundedRectangle" ;
        gpml:textlabel       "Glucose Import" ;
        gpml:type            "Pathway" ;
        gpml:valign          "Middle" ;
        gpml:width           "90.0"^^xsd:double ;
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/a409e>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP5345_r134459> ;
        gpml:color          "0" ;
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        gpml:graphId        "a409e" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/a409e/Point/e3a80e7407c79eb519045f7b297af109> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/a409e/Point/1ceb0934044ed15d2448f2e2f8b5a625> ;
        gpml:lineStyle      "Solid" ;
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/d6ae0/Point/e4490fa156d1472df7d633b39b5f3c34>
        rdf:type          gpml:Point ;
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        gpml:graphRef     "d9238" ;
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/c5a30>
        rdf:type             gpml:DataNode ;
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        gpml:fontWeight      "Bold" ;
        gpml:graphId         "c5a30" ;
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        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "RoundedRectangle" ;
        gpml:textlabel       "Neuron Morphogenesis" ;
        gpml:type            "Pathway" ;
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        gpml:xrefDataSource  "" ;
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Comment/c57ebaf9cbf54455398936e8fb8d7f7f>
        rdf:type          gpml:Comment ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/ead54> ;
        gpml:commentText  "Promotes profileration + migration via the Ras + MAPK pathway" .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/d083d>
        rdf:type             gpml:DataNode ;
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        gpml:color           "0" ;
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        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "d083d" ;
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        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "SDF4" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "90.00000000000026"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000078808" ;
        gpml:zorder          "32787"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/e50a0>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP5345_r134459> ;
        gpml:color          "0" ;
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/a1351>
        rdf:type             gpml:DataNode ;
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        gpml:fontWeight      "Normal" ;
        gpml:graphId         "a1351" ;
        gpml:height          "25.000000000000004"^^xsd:double ;
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        gpml:type            "GeneProduct" ;
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        gpml:xrefDataSource  "Ensembl" ;
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<https://identifiers.org/pubmed/22983350>
        rdf:type          gpml:PublicationXref ;
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        gpml:database     "Pubmed" ;
        gpml:id           "22983350" .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/c6675/Point/940075c58f99a4b4071157b29a2ae5a8>
        rdf:type          gpml:Point ;
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<https://identifiers.org/pubmed/9162022>
        rdf:type          gpml:PublicationXref ;
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        gpml:database     "Pubmed" ;
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Comment/86c9bef1edf61a2f03cc9b2a1d7946ad>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/ed25c/Point/ced9e56766dcab7efb1ee5e38f30aa43>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/bf6f1>
        rdf:type             gpml:DataNode ;
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<https://identifiers.org/pubmed/11399758>
        rdf:type          gpml:PublicationXref ;
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/a3c73>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/bdc26/Point/859603b0d97080c2e0505bd01805e480>
        rdf:type          gpml:Point ;
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/idc9dacc7a/Point/ba25feaa2387d0f3494dfcae9eb6e61c>
        rdf:type          gpml:Point ;
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/d144d>
        rdf:type             gpml:DataNode ;
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/ad1ff>
        rdf:type             gpml:DataNode ;
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/ece6a>
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        gpml:textlabel       "Mitochondrial Biogenesis " ;
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/aacd0>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/ide2d4c658/Point/d8d80f5acbf11e6a8ea6d2dbf4a4ee2c>
        rdf:type          gpml:Point ;
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/dfc24>
        rdf:type                 gpml:Interaction ;
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/GraphicalLine/ab62d/Point/919e67114ee58ff2d1063bed5293bd60>
        rdf:type          gpml:Point ;
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/idf19bf22/Point/d19a93ec7d3c4d913c73e2957db65807>
        rdf:type          gpml:Point ;
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/id872a29c0>
        rdf:type                 gpml:Interaction ;
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Comment/2cdca85f72129f9849042afe8b5faec1>
        rdf:type          gpml:Comment ;
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<https://identifiers.org/pubmed/26345236>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/b77f6/Point/271695e7904bf2376300cf548f6c56b3>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/e3528>
        rdf:type             gpml:DataNode ;
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/b8a77>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/c511b>
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        gpml:type            "Rna" ;
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/fc9b0>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5345_r134459> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Group/ef42d> ;
        gpml:align           "Center" ;
        gpml:centerX         "1066.0622303648588"^^xsd:double ;
        gpml:centerY         "1063.513675159567"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "fc9b0" ;
        gpml:groupRef        "d475c" ;
        gpml:hasComment      <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Comment/85baf379c7346dd1fc063cab4e6e4d5a> ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "FNDC10" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "90.0"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000228594" ;
        gpml:zorder          "33038"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/dcdfd/Point/1c60a4ac54813e0b822f45d2b5ecb70b>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5345_r134459> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/dcdfd> ;
        gpml:graphRef     "d0841" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "625.5519480519472"^^xsd:double ;
        gpml:y            "465.42207792207734"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/idf19bf22/Point/f1a86727c8b3e7f85b0aef74ac3e8688>
        rdf:type          gpml:Point ;
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        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "2961.224992733447"^^xsd:double ;
        gpml:y            "1097.2891853636484"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/a4ba9>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5345_r134459> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Group/dbdd8> ;
        gpml:align           "Center" ;
        gpml:centerX         "2419.2876336351915"^^xsd:double ;
        gpml:centerY         "1213.4647948362501"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "a4ba9" ;
        gpml:groupRef        "b53a8" ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "SMAD3" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "90.0"^^xsd:double ;
        gpml:xrefDataSource  "HGNC" ;
        gpml:xrefId          "SMAD3" ;
        gpml:zorder          "32949"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/f6729>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5345_r134459> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Group/e5817> ;
        gpml:align           "Center" ;
        gpml:centerX         "886.0622303648587"^^xsd:double ;
        gpml:centerY         "1263.5136751595667"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "f6729" ;
        gpml:groupRef        "d8018" ;
        gpml:height          "24.999999999999936"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "TRIM25" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "89.99999999999999"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000121060" ;
        gpml:zorder          "33033"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/e50a0/Point/875afaf7aedf8d283a8c38a1169570bd>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5345_r134459> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/e50a0> ;
        gpml:graphRef     "d2730" ;
        gpml:relX         "-0.5"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "585.596491228072"^^xsd:double ;
        gpml:y            "360.1491228070182"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/GraphicalLine/ab62d>
        rdf:type            gpml:GraphicalLine ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP5345_r134459> ;
        gpml:color          "ff0000" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "ab62d" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP5345_r134459/GraphicalLine/ab62d/Point/f6c467fe0dc393d04a6d3c56ee919f09> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/GraphicalLine/ab62d/Point/919e67114ee58ff2d1063bed5293bd60> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "32792"^^xsd:long .

<https://identifiers.org/pubmed/36578782>
        rdf:type          gpml:PublicationXref ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/id82ba66ef> ;
        gpml:database     "Pubmed" ;
        gpml:id           "36578782" .

<https://identifiers.org/pubmed/9153189>
        rdf:type          gpml:PublicationXref ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/dd698> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/id99efb4aa> ;
        gpml:database     "Pubmed" ;
        gpml:id           "9153189" .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/id6b05f823/Point/c063d1e0ee100dd590fe3820a804fd60>
        rdf:type          gpml:Point ;
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        gpml:graphRef     "e5ccd" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "3007.75"^^xsd:double ;
        gpml:y            "1124.25"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/ebc24>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5345_r134459> ;
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        gpml:color           "ff" ;
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        gpml:fontDecoration  "Normal" ;
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        gpml:fontWeight      "Normal" ;
        gpml:graphId         "ebc24" ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "NAD+" ;
        gpml:type            "Metabolite" ;
        gpml:valign          "Middle" ;
        gpml:width           "90.0"^^xsd:double ;
        gpml:xrefDataSource  "ChEBI" ;
        gpml:xrefId          "CHEBI:15846" ;
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<https://identifiers.org/pubmed/29180010>
        rdf:type          gpml:PublicationXref ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/idb0eb46ba> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/id872a29c0> ;
        gpml:database     "Pubmed" ;
        gpml:id           "29180010" .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/c8a17>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5345_r134459> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Group/f36ef> ;
        gpml:align           "Center" ;
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        gpml:fontDecoration  "Normal" ;
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        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Bold" ;
        gpml:graphId         "c8a17" ;
        gpml:groupRef        "b02e2" ;
        gpml:height          "34.802327381337875"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "RoundedRectangle" ;
        gpml:textlabel       "DNA repair pathways" ;
        gpml:type            "Pathway" ;
        gpml:valign          "Middle" ;
        gpml:width           "128.87034670852336"^^xsd:double ;
        gpml:xrefDataSource  "WikiPathways" ;
        gpml:xrefId          "WP4946" ;
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/d11f1/Point/15f45605daae18403b3a0172b7721d85>
        rdf:type          gpml:Point ;
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        gpml:graphRef     "fcf65" ;
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        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "2236.0622303648584"^^xsd:double ;
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/id6b05f823/Point/68921f8f615f1f42dfcb73ef5b75ce9e>
        rdf:type          gpml:Point ;
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        gpml:graphRef     "bd749" ;
        gpml:relX         "-1.0"^^xsd:double ;
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        gpml:x            "3015.75"^^xsd:double ;
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/cec32/Point/9bf67bd7ce45c4f723df9f62052cc232>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5345_r134459> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/cec32> ;
        gpml:graphRef     "b6696" ;
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        gpml:relY         "1.0"^^xsd:double ;
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        gpml:y            "1076.013675159567"^^xsd:double .

<https://identifiers.org/pubmed/33328586>
        rdf:type          gpml:PublicationXref ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/cec32> ;
        gpml:database     "Pubmed" ;
        gpml:id           "33328586" .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/ide2d4c658>
        rdf:type                 gpml:Interaction ;
        dcterms:isPartOf         <http://rdf.wikipathways.org/Pathway/WP5345_r134459> ;
        gpml:biopaxRef           "f2a" ;
        gpml:color               "0" ;
        gpml:connectorType       "Straight" ;
        gpml:graphId             "ide2d4c658" ;
        gpml:hasPoint            <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/ide2d4c658/Point/d8d80f5acbf11e6a8ea6d2dbf4a4ee2c> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/ide2d4c658/Point/b42d27560b00d4e16d80821ccda2e6d2> ;
        gpml:hasPublicationXref  <https://identifiers.org/pubmed/33551813> ;
        gpml:lineStyle           "Solid" ;
        gpml:lineThickness       "1.0"^^xsd:double ;
        gpml:zorder              "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/ceda9>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP5345_r134459> ;
        gpml:color          "0" ;
        gpml:connectorType  "Elbow" ;
        gpml:graphId        "ceda9" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/ceda9/Point/43eb1fe50c4830ea630ae8f0c8170084> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/ceda9/Point/3dc5b9917a09fe041b6899e1b07a3f8c> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "32920"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/id14d19cb3/Point/ae4b73b61a4b1be506d6f1670c9033d1>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5345_r134459> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/id14d19cb3> ;
        gpml:graphRef     "faaf9" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "1058.0964912280733"^^xsd:double ;
        gpml:y            "360.14912280701833"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/b0685>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5345_r134459> ;
        gpml:align           "Center" ;
        gpml:centerX         "2858.096491228077"^^xsd:double ;
        gpml:centerY         "347.6491228070183"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "b0685" ;
        gpml:height          "25.00000000000001"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "CPTP" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "90.00000000000001"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000224051" ;
        gpml:zorder          "33115"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/id379e9c6b/Point/1576d1f318855f6ca355031982675d9d>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5345_r134459> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/id379e9c6b> ;
        gpml:graphRef     "e6b7d" ;
        gpml:relX         "0.5"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "3110.4499854668948"^^xsd:double ;
        gpml:y            "1051.2891853636484"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/a36ea>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5345_r134459> ;
        gpml:align           "Center" ;
        gpml:centerX         "3170.1754385964928"^^xsd:double ;
        gpml:centerY         "1138.5964912280701"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "a36ea" ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "TRAF5" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "90.0"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000082512" ;
        gpml:zorder          "32768"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/adde5>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5345_r134459> ;
        gpml:align           "Center" ;
        gpml:centerX         "2987.9499854668943"^^xsd:double ;
        gpml:centerY         "1064.7891853636484"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "adde5" ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "HES5" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "90.0"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000197921" ;
        gpml:zorder          "32768"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/ff5dc/Point/27957f48e24fef11ec7f771ee2a0bee9>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5345_r134459> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/ff5dc> ;
        gpml:graphRef     "fb1e0" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "203.211007047588"^^xsd:double ;
        gpml:y            "1161.741740810557"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/id379e9c6b>
        rdf:type                 gpml:Interaction ;
        dcterms:isPartOf         <http://rdf.wikipathways.org/Pathway/WP5345_r134459> ;
        gpml:biopaxRef           "ec0" , "baa" ;
        gpml:color               "0" ;
        gpml:connectorType       "Straight" ;
        gpml:graphId             "id379e9c6b" ;
        gpml:hasPoint            <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/id379e9c6b/Point/1576d1f318855f6ca355031982675d9d> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/id379e9c6b/Point/c98adf45c138a865ee2126237726ec11> ;
        gpml:hasPublicationXref  <https://identifiers.org/pubmed/18193050> , <https://identifiers.org/pubmed/23761635> ;
        gpml:lineStyle           "Solid" ;
        gpml:lineThickness       "1.0"^^xsd:double ;
        gpml:zorder              "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/f861c>
        rdf:type             gpml:DataNode ;
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/f0e62>
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<https://identifiers.org/pubmed/36459505>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/bd8d4/Point/93ba45eaeed1d6db8415c651d771dd51>
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<https://identifiers.org/pubmed/29559363>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/id316f2e27/Point/ac1ce30a3eae07dc2c991d3c7de4cda7>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/fcf96>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/e1ad0>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Group/d0d64>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/ccf6e>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/ceb80/Point/b7d647cb0653648e878572c4629797a0>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/id33030e3/Point/82353ab490b96b17ee850f378acca0a1>
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<https://identifiers.org/pubmed/19217376>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/id316f2e27>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/bd9a8>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/b3d73>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Group/ebcb4>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/bbf12>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Label/c49f2>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/idecdead92/Point/2e5cd9a7156e1e6a79a03f17e9b7142d>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/dd698/Point/92b1b370c00b4fc0b07c3f18af463637>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/ba5a6/Point/17758066e6c11d2792119e6f094bb9bc>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Comment/462eab0b4379fb3e7c4569ccae319e50>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/e51a3>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/b9e93>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/aacd0/Point/4e40f3e087731a2a2feb4ee9a032e2f1>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/da179>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Group/ab487>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/b58bd/Point/86367a5e416fb84ec91261654f0252b6>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Label/fc44f>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/b77f6>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/b6e17/Point/e8a9dae9e93e9bfa9b877cc98f1c63a7>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/f64d4/Point/e3162c4766e5e58c83a673f34a69adbf>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/id99efb4aa>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/a8fda>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/e099d>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/idd36a2d2/Point/f512247ccea238e9dde9cac0b131f28e>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/ec349>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/ea148/Point/2909e53c5ea3132288d2229dd88555a1>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/id21fea3ee/Point/5999a36205813a6f52935867a22375a4>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Label/d08c4>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/f64d4/Point/3fadf1def07643db0bcae2f8853ea4c3>
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/d371a>
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        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "d371a" ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "GNB1" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "90.0"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000078369" ;
        gpml:zorder          "32963"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/e1fe8/Point/9e0dbd57907402e2599a6067e83b70c8>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5345_r134459> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/e1fe8> ;
        gpml:graphRef     "d3e76" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "524.4105363441474"^^xsd:double ;
        gpml:y            "1370.0736411120913"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Group/b48b4>
        rdf:type          gpml:Group ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5345_r134459> ;
        gpml:graphId      "b48b4" ;
        gpml:groupId      "b5518" ;
        gpml:style        "Group" .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/cdf04>
        rdf:type                 gpml:Interaction ;
        dcterms:isPartOf         <http://rdf.wikipathways.org/Pathway/WP5345_r134459> ;
        gpml:biopaxRef           "f31" ;
        gpml:color               "0" ;
        gpml:connectorType       "Straight" ;
        gpml:graphId             "cdf04" ;
        gpml:hasPoint            <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/cdf04/Point/6c558ad2c72f8667c4cebb1ac4a8b5f8> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/cdf04/Point/a392acd52d41bc4d0916d9c5cd96bf13> ;
        gpml:hasPublicationXref  <https://identifiers.org/pubmed/19217376> ;
        gpml:lineStyle           "Solid" ;
        gpml:lineThickness       "1.0"^^xsd:double ;
        gpml:zorder              "32985"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/ea174>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5345_r134459> ;
        gpml:align           "Center" ;
        gpml:centerX         "2678.0964912280765"^^xsd:double ;
        gpml:centerY         "347.6491228070183"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "ea174" ;
        gpml:height          "25.00000000000001"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "INTS11\n" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "90.00000000000001"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000127054" ;
        gpml:zorder          "33087"^^xsd:long .

<https://identifiers.org/pubmed/29452073>
        rdf:type          gpml:PublicationXref ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/e007f> ;
        gpml:database     "Pubmed" ;
        gpml:id           "29452073" .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/id3f86f5b7>
        rdf:type                 gpml:Interaction ;
        dcterms:isPartOf         <http://rdf.wikipathways.org/Pathway/WP5345_r134459> ;
        gpml:biopaxRef           "fcb" ;
        gpml:color               "0" ;
        gpml:connectorType       "Straight" ;
        gpml:graphId             "id3f86f5b7" ;
        gpml:hasPoint            <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/id3f86f5b7/Point/76adf11deb402d2b365b05dcd0ab2dcd> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/id3f86f5b7/Point/938f9cccedbdf6a08b665d738cd32fad> ;
        gpml:hasPublicationXref  <https://identifiers.org/pubmed/35217789> ;
        gpml:lineStyle           "Solid" ;
        gpml:lineThickness       "1.0"^^xsd:double ;
        gpml:zorder              "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/e0907>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5345_r134459> ;
        gpml:align           "Center" ;
        gpml:centerX         "1246.0622303648588"^^xsd:double ;
        gpml:centerY         "1063.513675159567"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "e0907" ;
        gpml:hasComment      <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Comment/4d66ab12f9b95e2246e69a3562787c8d> ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "MIB2" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "90.0"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000197530" ;
        gpml:zorder          "33045"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/id33030e3/Point/ee3a4787fb41c028923469f78cae30fe>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5345_r134459> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/id33030e3> ;
        gpml:graphRef     "e8d16" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "2595.0861533841176"^^xsd:double ;
        gpml:y            "1111.6790639573642"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/id872a29c0/Point/5ceef0c2a21c2121de8aebd5da5dc62c>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5345_r134459> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/id872a29c0> ;
        gpml:graphRef     "ec247" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "879.4262858266845"^^xsd:double ;
        gpml:y            "467.3514713624372"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/c8cc3>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Group/dbdd8> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459> ;
        gpml:align           "Center" ;
        gpml:centerX         "2419.2876336351915"^^xsd:double ;
        gpml:centerY         "1238.4647948362503"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "c8cc3" ;
        gpml:groupRef        "b53a8" ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "SMAD4" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "90.0"^^xsd:double ;
        gpml:xrefDataSource  "HGNC" ;
        gpml:xrefId          "SMAD4" ;
        gpml:zorder          "32956"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/ffd7d>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5345_r134459> ;
        gpml:align           "Center" ;
        gpml:centerX         "2684.7242091206917"^^xsd:double ;
        gpml:centerY         "788.8135914266414"^^xsd:double ;
        gpml:color           "14961e" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Bold" ;
        gpml:graphId         "ffd7d" ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "RoundedRectangle" ;
        gpml:textlabel       "mRNA 3'-Processing\n" ;
        gpml:type            "Pathway" ;
        gpml:valign          "Middle" ;
        gpml:width           "134.83666061705958"^^xsd:double ;
        gpml:xrefDataSource  "Reactome" ;
        gpml:xrefId          "R-HSA-72187" ;
        gpml:zorder          "33092"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/ecf1c/Point/a3e7d22053fc17c85aa7b2bc9ccbdfcd>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5345_r134459> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/ecf1c> ;
        gpml:graphRef     "ebc24" ;
        gpml:relX         "1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "1652.4635905364592"^^xsd:double ;
        gpml:y            "1375.8673741583682"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/id65c177c9/Point/55240aee60476aaf6538905f5779061c>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5345_r134459> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/id65c177c9> ;
        gpml:graphRef     "d56a3" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "2690.938570899494"^^xsd:double ;
        gpml:y            "1489.060958432344"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/e9798>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5345_r134459> ;
        gpml:align           "Center" ;
        gpml:centerX         "202.46100704758788"^^xsd:double ;
        gpml:centerY         "1273.9917408105573"^^xsd:double ;
        gpml:color           "14961e" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Bold" ;
        gpml:graphId         "e9798" ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "RoundedRectangle" ;
        gpml:textlabel       "PI3K-Akt" ;
        gpml:type            "Pathway" ;
        gpml:valign          "Middle" ;
        gpml:width           "90.0"^^xsd:double ;
        gpml:xrefDataSource  "WikiPathways" ;
        gpml:xrefId          "WP4172" ;
        gpml:zorder          "33097"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/dd698/Point/f279c0c441a6fdf3f4b756e96d96e86>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5345_r134459> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/dd698> ;
        gpml:graphRef     "e6b7d" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "3087.9499854668948"^^xsd:double ;
        gpml:y            "1076.2891853636484"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/id14d19cb3/Point/c1fcedeff16048c020bf6dddfa66d0e8>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5345_r134459> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/id14d19cb3> ;
        gpml:graphRef     "f3822" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "1058.5549046330875"^^xsd:double ;
        gpml:y            "397.41707708114245"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/dbba7>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP5345_r134459> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "dbba7" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/dbba7/Point/1a89aff912a593bda95f7bebfbc9403f> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/dbba7/Point/9f5d4584fc13d6e3c9cc92c403dd8cd2> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "32912"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/id99efb4aa/Point/23550e233687febef3401dbb49304b7d>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5345_r134459> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/id99efb4aa> ;
        gpml:graphRef     "a36ea" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "3125.1754385964928"^^xsd:double ;
        gpml:y            "1138.5964912280701"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/e1fe8/Point/96abe087c49c21de96bab6cd877223ac>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5345_r134459> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/e1fe8> ;
        gpml:graphRef     "d0d64" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "524.4105363441474"^^xsd:double ;
        gpml:y            "1347.2459746005825"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Group/c9272>
        rdf:type          gpml:Group ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5345_r134459> ;
        gpml:graphId      "c9272" ;
        gpml:groupId      "c9eb8" ;
        gpml:style        "Group" .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/da179/Point/33871990b37b475c6f81354bdf0d7767>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5345_r134459> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/da179> ;
        gpml:graphRef     "d59ed" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "248.09649122807093"^^xsd:double ;
        gpml:y            "360.1491228070182"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/a5367>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5345_r134459> ;
        gpml:align           "Center" ;
        gpml:centerX         "1508.5967053081142"^^xsd:double ;
        gpml:centerY         "440.82977425259327"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "a5367" ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "TNFSF18" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "90.0"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000120337" ;
        gpml:zorder          "32768"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/c6eb2>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5345_r134459> ;
        gpml:align           "Center" ;
        gpml:centerX         "1516.062230364859"^^xsd:double ;
        gpml:centerY         "1063.513675159567"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "c6eb2" ;
        gpml:hasComment      <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Comment/462eab0b4379fb3e7c4569ccae319e50> ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "SLC35E2B" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "90.0"^^xsd:double ;
        gpml:xrefDataSource  "HGNC" ;
        gpml:xrefId          "SLC35E2B" ;
        gpml:zorder          "33039"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/dfc98>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5345_r134459> ;
        gpml:align           "Center" ;
        gpml:centerX         "2228.096491228076"^^xsd:double ;
        gpml:centerY         "347.6491228070183"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "dfc98" ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "UBE2J2" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "90.0"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000160087" ;
        gpml:zorder          "33117"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/GraphicalLine/ab62d/Point/f6c467fe0dc393d04a6d3c56ee919f09>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5345_r134459> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/GraphicalLine/ab62d> ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "3012.1506682867557"^^xsd:double ;
        gpml:y            "326.8529769137303"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/id316f2e27/Point/a1ad7ebbf25b42c2f87ed84cc9c8b137>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5345_r134459> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/id316f2e27> ;
        gpml:graphRef     "f1f5a" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "796.0622303648586"^^xsd:double ;
        gpml:y            "1076.013675159567"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/f6612>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Group/e54fb> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459> ;
        gpml:align           "Center" ;
        gpml:centerX         "1402.0807037712684"^^xsd:double ;
        gpml:centerY         "1429.5281659059747"^^xsd:double ;
        gpml:color           "14961e" ;
        gpml:fillColor       "ffffff" ;
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        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Bold" ;
        gpml:graphId         "f6612" ;
        gpml:groupRef        "d519e" ;
        gpml:height          "29.75"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "RoundedRectangle" ;
        gpml:textlabel       "Chronic hyperglycemia impairment \nof neuron function " ;
        gpml:type            "Pathway" ;
        gpml:valign          "Middle" ;
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        gpml:xrefDataSource  "WikiPathways" ;
        gpml:xrefId          "WP5283" ;
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/cf095/Point/3729570be6fe49eea38cd00eedc87bb6>
        rdf:type          gpml:Point ;
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        gpml:graphRef     "e5bd1" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "692.9525681490669"^^xsd:double ;
        gpml:y            "1125.8343960614268"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/DataNode/eed1a>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5345_r134459> ;
        gpml:align           "Center" ;
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        gpml:centerY         "347.6491228070182"^^xsd:double ;
        gpml:color           "9900cc" ;
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        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
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        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "eed1a" ;
        gpml:hasComment      <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Comment/91be8285fefd082825e5b98baecdd915> ;
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        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "MIR6859-2" ;
        gpml:type            "Rna" ;
        gpml:valign          "Middle" ;
        gpml:width           "90.0000000000002"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000273874" ;
        gpml:zorder          "32804"^^xsd:long .

<https://identifiers.org/pubmed/30846598>
        rdf:type          gpml:PublicationXref ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/c9c0f> ;
        gpml:database     "Pubmed" ;
        gpml:id           "30846598" .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/b4f9a>
        rdf:type                 gpml:Interaction ;
        dcterms:isPartOf         <http://rdf.wikipathways.org/Pathway/WP5345_r134459> ;
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        gpml:color               "0" ;
        gpml:connectorType       "Straight" ;
        gpml:graphId             "b4f9a" ;
        gpml:hasPoint            <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/b4f9a/Point/49182b237123fa3dae57a011b5fecb40> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/b4f9a/Point/27d9da6a62e0959145c1637cf5b1ee33> ;
        gpml:hasPublicationXref  <https://identifiers.org/pubmed/18216018> ;
        gpml:lineStyle           "Solid" ;
        gpml:lineThickness       "1.0"^^xsd:double ;
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<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/ba5a6/Point/a592417ca3fa77732205ea195ffdbf88>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5345_r134459> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/ba5a6> ;
        gpml:graphRef     "ead54" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "788.0964912280725"^^xsd:double ;
        gpml:y            "360.14912280701833"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/bd8d4>
        rdf:type                 gpml:Interaction ;
        dcterms:isPartOf         <http://rdf.wikipathways.org/Pathway/WP5345_r134459> ;
        gpml:biopaxRef           "ed1" ;
        gpml:color               "0" ;
        gpml:connectorType       "Straight" ;
        gpml:graphId             "bd8d4" ;
        gpml:hasPoint            <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/bd8d4/Point/dd8334cd1d031af5353fe7f83a97b48> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/bd8d4/Point/93ba45eaeed1d6db8415c651d771dd51> ;
        gpml:hasPublicationXref  <https://identifiers.org/pubmed/33177874> ;
        gpml:lineStyle           "Solid" ;
        gpml:lineThickness       "1.0"^^xsd:double ;
        gpml:zorder              "32925"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/fcf96/Point/539ba7f28e7bcfc5cb5bc2e5a11d8eb8>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5345_r134459> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/fcf96> ;
        gpml:graphRef     "d08c4" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "1446.6125012526247"^^xsd:double ;
        gpml:y            "1322.935287806963"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/ef2fd>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP5345_r134459> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "ef2fd" ;
        gpml:hasAnchor      <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/ef2fd/Anchor/dc3cd> ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/ef2fd/Point/87821fc2bd403598cbfc22aedbf20429> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/ef2fd/Point/fd0d9312a9d5e5bf203a70c04fd8e06e> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "32909"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/dbba7/Point/1a89aff912a593bda95f7bebfbc9403f>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5345_r134459> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/dbba7> ;
        gpml:graphRef     "bbc4b" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "1875.7383612167869"^^xsd:double ;
        gpml:y            "1303.890874295174"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/id59643fc3>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP5345_r134459> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "id59643fc3" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/id59643fc3/Point/b8b6a2bd1a38b234b5d95a49cb6c6182> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/id59643fc3/Point/677c9a4c3961fd3969415c707128f892> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/e007f/Point/1d629d7d1bf897d393fd531a948972fc>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5345_r134459> , <http://rdf.wikipathways.org/Pathway/WP5345_r134459/Interaction/e007f> ;
        gpml:graphRef     "b5360" ;
        gpml:relX         "-0.5"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "2115.596491228076"^^xsd:double ;
        gpml:y            "360.1491228070183"^^xsd:double .
