@prefix biopax:  <http://www.biopax.org/release/biopax-level3.owl#> .
@prefix cito:    <http://purl.org/spar/cito/> .
@prefix dc:      <http://purl.org/dc/elements/1.1/> .
@prefix dcterms: <http://purl.org/dc/terms/> .
@prefix foaf:    <http://xmlns.com/foaf/0.1/> .
@prefix freq:    <http://purl.org/cld/freq/> .
@prefix gpml:    <http://vocabularies.wikipathways.org/gpml#> .
@prefix obo:     <http://purl.obolibrary.org/obo/> .
@prefix owl:     <http://www.w3.org/2002/07/owl#> .
@prefix pav:     <http://purl.org/pav/> .
@prefix prov:    <http://www.w3.org/ns/prov#> .
@prefix rdf:     <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix rdfs:    <http://www.w3.org/2000/01/rdf-schema#> .
@prefix skos:    <http://www.w3.org/2004/02/skos/core#> .
@prefix void:    <http://rdfs.org/ns/void#> .
@prefix wp:      <http://vocabularies.wikipathways.org/wp#> .
@prefix wprdf:   <http://rdf.wikipathways.org/> .
@prefix xsd:     <http://www.w3.org/2001/XMLSchema#> .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/idcf61ccc8>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "idcf61ccc8" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/idcf61ccc8/Point/473fabf1eb92d290856c7ff7019e5624> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/idcf61ccc8/Point/3a085b0d3628fcd687164bec7b62a82> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/b0ab3>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Group/dd419> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:align           "Center" ;
        gpml:centerX         "364.0656636373991"^^xsd:double ;
        gpml:centerY         "347.9870589354298"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "b0ab3" ;
        gpml:groupRef        "b1ebf" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "AKT1" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "70.0"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000142208" ;
        gpml:zorder          "32822"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/idee431d35>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "idee431d35" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/idee431d35/Point/a3e7d22053fc17c85aa7b2bc9ccbdfcd> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/idee431d35/Point/dd8334cd1d031af5353fe7f83a97b48> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/GraphicalLine/ca171/Point/539ba7f28e7bcfc5cb5bc2e5a11d8eb8>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/GraphicalLine/ca171> ;
        gpml:graphRef     "efff3" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "1265.3205128205157"^^xsd:double ;
        gpml:y            "218.38461538461502"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/f403a/Point/17758066e6c11d2792119e6f094bb9bc>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/f403a> ;
        gpml:graphRef     "a29ba" ;
        gpml:relX         "0.5"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "477.45139833759333"^^xsd:double ;
        gpml:y            "579.6341241865046"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id6f89564e>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:color          "0" ;
        gpml:connectorType  "Elbow" ;
        gpml:graphId        "id6f89564e" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id6f89564e/Point/bf59eecfe5956b2eda2b525cb8a05617> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id6f89564e/Point/ac156fcf6d52b7a479347e1aefcd5581> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/State/c3500>
        rdf:type                 gpml:State ;
        dcterms:isPartOf         <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:biopaxRef           "fb2" ;
        gpml:color               "0" ;
        gpml:fillColor           "ffffff" ;
        gpml:graphId             "c3500" ;
        gpml:graphRef            "dcfec" ;
        gpml:hasPublicationXref  <https://identifiers.org/pubmed/31695792> ;
        gpml:height              "15.0"^^xsd:double ;
        gpml:lineStyle           "Solid" ;
        gpml:lineThickness       "1.0"^^xsd:double ;
        gpml:relX                "-1.0"^^xsd:double ;
        gpml:relY                "-0.9"^^xsd:double ;
        gpml:shapeType           "Hexagon" ;
        gpml:stateOf             <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/dcfec> ;
        gpml:stateType           "Unknown" ;
        gpml:textlabel           "" ;
        gpml:width               "15.0"^^xsd:double ;
        gpml:zorder              "32769"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/GraphicalLine/ab138/Point/710f88eda7e56e31c9ae87fa155d7ca6>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/GraphicalLine/ab138> ;
        gpml:graphRef     "f688a" ;
        gpml:relX         "-0.5"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "120.83843388588383"^^xsd:double ;
        gpml:y            "859.7230517595494"^^xsd:double .

<https://identifiers.org/pubmed/12150915>
        rdf:type          gpml:PublicationXref ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545/State/afb39> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/State/a8c22> ;
        gpml:database     "Pubmed" ;
        gpml:id           "12150915" .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/idcf61ccc8/Point/473fabf1eb92d290856c7ff7019e5624>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/idcf61ccc8> ;
        gpml:graphRef     "e8b0f" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "668.6245638254368"^^xsd:double ;
        gpml:y            "151.5234899328859"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id3cd48500>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "id3cd48500" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id3cd48500/Point/ee8ca04ab66111fe203738b9c4b40a08> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id3cd48500/Point/b620cf0922c5c7c252dc318322069c03> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Label/fe637>
        rdf:type             gpml:Label ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:align           "Center" ;
        gpml:centerX         "661.4465370595332"^^xsd:double ;
        gpml:centerY         "613.6166306763446"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Bold" ;
        gpml:graphId         "fe637" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:href            "" ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "None" ;
        gpml:textlabel       "Multiple other targets" ;
        gpml:valign          "Middle" ;
        gpml:width           "144.6354799513972"^^xsd:double ;
        gpml:zorder          "28672"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/ida8acd52d>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "ida8acd52d" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/ida8acd52d/Point/666f7bb88b4ed87d9cca63b8754df210> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/ida8acd52d/Point/4ec30aedcaf8fc15c11c39a9bcec6007> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/GraphicalLine/f2390/Point/3e623da4d810a8bb273fe6424fbaeda>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/GraphicalLine/f2390> ;
        gpml:graphRef     "f93a1" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "1068.9040097205325"^^xsd:double ;
        gpml:y            "898.3701824908654"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/f688a>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:align           "Center" ;
        gpml:centerX         "138.33843388588383"^^xsd:double ;
        gpml:centerY         "849.7230517595494"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "f688a" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "TP53" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "70.0"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000141510" ;
        gpml:zorder          "32768"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/e4b3f/Point/a592417ca3fa77732205ea195ffdbf88>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/e4b3f> ;
        gpml:graphRef     "a29ba" ;
        gpml:relX         "1.0"^^xsd:double ;
        gpml:relY         "-0.5"^^xsd:double ;
        gpml:x            "516.7777777777779"^^xsd:double ;
        gpml:y            "530.9293643799601"^^xsd:double .

<https://identifiers.org/pubmed/23847349>
        rdf:type          gpml:PublicationXref ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/ida0b85c43> ;
        gpml:database     "Pubmed" ;
        gpml:id           "23847349" .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/bb45e>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:align           "Center" ;
        gpml:centerX         "756.7013422818796"^^xsd:double ;
        gpml:centerY         "192.53020134228194"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "bb45e" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "TRAF3" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "70.0"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000131323" ;
        gpml:zorder          "33823"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id88ef9d84/Point/d0a8cc16a4e0228ad8482e4828bc2ad0>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id88ef9d84> ;
        gpml:graphRef     "b781d" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "1001.2586290699271"^^xsd:double ;
        gpml:y            "816.7750697521741"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/idaf4c7f80/Point/a31c3a606d3a31c8c07c4457a3948cb1>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/idaf4c7f80> ;
        gpml:graphRef     "ee837" ;
        gpml:relX         "1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "656.5434547434534"^^xsd:double ;
        gpml:y            "520.7755544041449"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id5ef1a8e/Point/3d7ba9a912ae2f5630210ce51e069e04>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id5ef1a8e> ;
        gpml:graphRef     "f0d17" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "627.5583232077771"^^xsd:double ;
        gpml:y            "1038.2855407047414"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id5fe91b3e>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:color          "0" ;
        gpml:connectorType  "Elbow" ;
        gpml:graphId        "id5fe91b3e" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id5fe91b3e/Point/d48832eea947bb479e6158ed415db27b> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id5fe91b3e/Point/23550e233687febef3401dbb49304b7d> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id907c03df/Point/33871990b37b475c6f81354bdf0d7767>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id907c03df> ;
        gpml:graphRef     "fc7b8" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "272.39368165249095"^^xsd:double ;
        gpml:y            "303.42244243122514"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/c6073>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Group/deb35> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:align           "Center" ;
        gpml:centerX         "599.2717750826902"^^xsd:double ;
        gpml:centerY         "553.6758544652702"^^xsd:double ;
        gpml:color           "ff" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "c6073" ;
        gpml:groupRef        "e2a6a" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "Rapamycin" ;
        gpml:type            "Metabolite" ;
        gpml:valign          "Middle" ;
        gpml:width           "73.66593164277833"^^xsd:double ;
        gpml:xrefDataSource  "ChEBI" ;
        gpml:xrefId          "CHEBI:9168" ;
        gpml:zorder          "32768"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/idcf61ccc8/Point/3a085b0d3628fcd687164bec7b62a82>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/idcf61ccc8> ;
        gpml:graphRef     "fbf7f" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "668.6245638254369"^^xsd:double ;
        gpml:y            "183.1301296992832"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/b71e6/Point/bcdfbf15d7c5dd38e523aaddaf3cc71f>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/b71e6> ;
        gpml:graphRef     "f77f0" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "438.0656636373991"^^xsd:double ;
        gpml:y            "394.04153159391217"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/State/b7b88>
        rdf:type            gpml:State ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:color          "0" ;
        gpml:fillColor      "ffffff" ;
        gpml:graphId        "b7b88" ;
        gpml:graphRef       "c0391" ;
        gpml:hasComment     <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Comment/b1e04841cf8863e2da357146d5004da6> ;
        gpml:height         "15.0"^^xsd:double ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:relX           "0.9142857142857143"^^xsd:double ;
        gpml:relY           "1.0"^^xsd:double ;
        gpml:shapeType      "Oval" ;
        gpml:stateOf        <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/c0391> ;
        gpml:stateType      "Unknown" ;
        gpml:textlabel      "P" ;
        gpml:width          "15.0"^^xsd:double ;
        gpml:zorder         "33811"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/State/ed908>
        rdf:type                 gpml:State ;
        dcterms:isPartOf         <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:biopaxRef           "fb2" ;
        gpml:color               "0" ;
        gpml:fillColor           "ffffff" ;
        gpml:graphId             "ed908" ;
        gpml:graphRef            "c0dd4" ;
        gpml:hasPublicationXref  <https://identifiers.org/pubmed/31695792> ;
        gpml:height              "15.0"^^xsd:double ;
        gpml:lineStyle           "Solid" ;
        gpml:lineThickness       "1.0"^^xsd:double ;
        gpml:relX                "-0.9407661983220564"^^xsd:double ;
        gpml:relY                "-0.7636632200886265"^^xsd:double ;
        gpml:shapeType           "Hexagon" ;
        gpml:stateOf             <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/c0dd4> ;
        gpml:stateType           "Unknown" ;
        gpml:textlabel           "" ;
        gpml:width               "15.0"^^xsd:double ;
        gpml:zorder              "32769"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/b173b>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:align           "Center" ;
        gpml:centerX         "487.9668457046315"^^xsd:double ;
        gpml:centerY         "951.8974964354733"^^xsd:double ;
        gpml:color           "14961e" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Bold" ;
        gpml:graphId         "b173b" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "RoundedRectangle" ;
        gpml:textlabel       "Apoptosis" ;
        gpml:type            "Pathway" ;
        gpml:valign          "Middle" ;
        gpml:width           "90.0"^^xsd:double ;
        gpml:xrefDataSource  "WikiPathways" ;
        gpml:xrefId          "WP254" ;
        gpml:zorder          "32768"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id793259d9/Point/9f76dbf219d779ee6e963bc9dcea2d88>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id793259d9> ;
        gpml:graphRef     "dcfe8" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "593.0857213891379"^^xsd:double ;
        gpml:y            "872.1733231913109"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/idacd50709>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "idacd50709" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/idacd50709/Point/57f14fcdd506ca8d6e8b22de89eda141> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/idacd50709/Point/619414fc45473171e6c2f81aa0bfacd6> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id19ff6cd6/Point/88cf3bbafe1c06a7e51e7d8be6f42a66>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id19ff6cd6> ;
        gpml:graphRef     "cf704" ;
        gpml:relX         "-0.5"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "739.2013422818796"^^xsd:double ;
        gpml:y            "151.5234899328859"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/b9db3>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:align           "Center" ;
        gpml:centerX         "534.8636368750282"^^xsd:double ;
        gpml:centerY         "685.1468160865431"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "b9db3" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "RPS6" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "70.0"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000137154" ;
        gpml:zorder          "32865"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/c0dd4>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:align           "Center" ;
        gpml:centerX         "1160.5649926144752"^^xsd:double ;
        gpml:centerY         "127.55933037912342"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "c0dd4" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "AJUBA" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "70.0"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000129474" ;
        gpml:zorder          "32768"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Group/c8d56>
        rdf:type          gpml:Group ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:graphId      "c8d56" ;
        gpml:groupId      "ea664" ;
        gpml:style        "Group" .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/ee18e>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:align           "Center" ;
        gpml:centerX         "427.9108955637061"^^xsd:double ;
        gpml:centerY         "849.7230517595494"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "ee18e" ;
        gpml:height          "36.22056314756787"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "p14 ARF \n(CDKN2A)" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "70.0"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000147889" ;
        gpml:zorder          "33757"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id3fb4e606>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:color          "0" ;
        gpml:connectorType  "Elbow" ;
        gpml:graphId        "id3fb4e606" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id3fb4e606/Point/e582665bef98f5ddb6301df1bc5b900a> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id3fb4e606/Point/6e8bd5a05e3ecbbc5ecaedcc4169eec7> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id3fb4e606/Point/ad01556e22fd8d730757efe9c1139ee6> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id3fb4e606/Point/6e0ca7dce00f3dc4a38beba61641ce7e> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/GraphicalLine/ffa51>
        rdf:type            gpml:GraphicalLine ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:color          "0" ;
        gpml:connectorType  "Elbow" ;
        gpml:graphId        "ffa51" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP4674_r142545/GraphicalLine/ffa51/Point/808f18b7f049cccb20e51f7781217431> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/GraphicalLine/ffa51/Point/ca50552a71f8464e339b89db101345d1> ;
        gpml:lineStyle      "Broken" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/GraphicalLine/c337b/Point/7515af1d84a1f5d6a81ee53d81b7d79b>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/GraphicalLine/c337b> ;
        gpml:graphRef     "f4221" ;
        gpml:relX         "0.5"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "1199.509649929772"^^xsd:double ;
        gpml:y            "508.15081308220147"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id2db3d091>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Group/d6359> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "id2db3d091" ;
        gpml:groupRef       "c7c51" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id2db3d091/Point/1a912f3fb4b8c26812a91b0ddbb1556b> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id2db3d091/Point/c8bac20697a75afd636f353874987899> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/idd761eea6/Point/deb057d0dc85d9cffe90b73be3a645ff>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/idd761eea6> ;
        gpml:graphRef     "fe6d3" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "768.7786190008744"^^xsd:double ;
        gpml:y            "477.6322498184127"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id69d506bd>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "id69d506bd" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id69d506bd/Point/a387153ecbb09e1e1be7cebb7e730bb5> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id69d506bd/Point/47892db9c36e660fc38bd4f9bdb1a266> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id42078bd4/Point/86fe90a2db0ac9ab1875e2e04230639a>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id42078bd4> ;
        gpml:graphRef     "e2561" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "1265.320512820516"^^xsd:double ;
        gpml:y            "168.26495726495716"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id870ef7e2/Point/120b26b3a316b7e288c6f06858769414>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id870ef7e2> ;
        gpml:graphRef     "c0dd4" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "1160.5649926144752"^^xsd:double ;
        gpml:y            "137.55933037912342"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id960f1d40>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "id960f1d40" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id960f1d40/Point/fd0d9312a9d5e5bf203a70c04fd8e06e> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id960f1d40/Point/87821fc2bd403598cbfc22aedbf20429> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/f0d17>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:align           "Center" ;
        gpml:centerX         "627.5583232077771"^^xsd:double ;
        gpml:centerY         "1048.2855407047414"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "f0d17" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "E2F1" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "70.0"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000101412" ;
        gpml:zorder          "32768"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id93942fc8/Point/4e40f3e087731a2a2feb4ee9a032e2f1>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id93942fc8> ;
        gpml:graphRef     "af03a" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "867.3232077764277"^^xsd:double ;
        gpml:y            "797.8173349534219"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/ida0b85c43/Point/837fbb4c49d4ea36c04554afd80f3433>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/ida0b85c43> ;
        gpml:graphRef     "f9f69" ;
        gpml:relX         "-0.5"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "978.6004273504259"^^xsd:double ;
        gpml:y            "88.5"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id9cf21b4e>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "id9cf21b4e" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id9cf21b4e/Point/1a89aff912a593bda95f7bebfbc9403f> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id9cf21b4e/Point/9f5d4584fc13d6e3c9cc92c403dd8cd2> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id1209ef14/Point/dbe91860511544b264c1d84d6fb50503>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id1209ef14> ;
        gpml:graphRef     "f688a" ;
        gpml:relX         "1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "173.33843388588383"^^xsd:double ;
        gpml:y            "849.7230517595494"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/b92bc>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Group/baa75> ;
        gpml:align           "Center" ;
        gpml:centerX         "237.1572011129855"^^xsd:double ;
        gpml:centerY         "223.127"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "b92bc" ;
        gpml:groupRef        "ac87c" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "PIK3CA" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "70.0"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000121879" ;
        gpml:zorder          "32830"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/State/d23da>
        rdf:type                 gpml:State ;
        dcterms:isPartOf         <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:biopaxRef           "fb2" ;
        gpml:color               "0" ;
        gpml:fillColor           "ffffff" ;
        gpml:graphId             "d23da" ;
        gpml:graphRef            "de84f" ;
        gpml:hasPublicationXref  <https://identifiers.org/pubmed/31695792> ;
        gpml:height              "15.0"^^xsd:double ;
        gpml:lineStyle           "Solid" ;
        gpml:lineThickness       "1.0"^^xsd:double ;
        gpml:relX                "-1.0"^^xsd:double ;
        gpml:relY                "-0.4"^^xsd:double ;
        gpml:shapeType           "Hexagon" ;
        gpml:stateOf             <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/de84f> ;
        gpml:stateType           "Unknown" ;
        gpml:textlabel           "" ;
        gpml:width               "15.0"^^xsd:double ;
        gpml:zorder              "33814"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/GraphicalLine/fb4a2/Point/ce9e773ec52ec66a099053cc62abee88>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/GraphicalLine/fb4a2> ;
        gpml:graphRef     "b43d0" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "1112.2581240768075"^^xsd:double ;
        gpml:y            "218.38461538461502"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/d853e/Point/a392acd52d41bc4d0916d9c5cd96bf13>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/d853e> ;
        gpml:graphRef     "d2be7" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "403.0656636373991"^^xsd:double ;
        gpml:y            "233.12679162072772"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/d8776>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Group/baa75> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:align           "Center" ;
        gpml:centerX         "307.1572011129855"^^xsd:double ;
        gpml:centerY         "223.127"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "d8776" ;
        gpml:groupRef        "ac87c" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "PIK3CB" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "70.0"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000051382" ;
        gpml:zorder          "32831"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/e6270>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Group/af5e4> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:align           "Center" ;
        gpml:centerX         "752.4567847882455"^^xsd:double ;
        gpml:centerY         "301.10544511668036"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "e6270" ;
        gpml:groupRef        "cdbf1" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "REL" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "70.0"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000162924" ;
        gpml:zorder          "33831"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/ca5cf>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Group/fe6d3> ;
        gpml:align           "Center" ;
        gpml:centerX         "805.591119000874"^^xsd:double ;
        gpml:centerY         "521.6785461147092"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "ca5cf" ;
        gpml:groupRef        "a3124" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "MLST8" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "70.0"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000167965" ;
        gpml:zorder          "32861"^^xsd:long .

<https://identifiers.org/pubmed/31695792>
        rdf:type          gpml:PublicationXref ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545/State/e9095> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/State/fc5e0> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/State/c2672> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/State/c522c> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/State/fda26> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/State/ed908> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/State/d23da> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/idc4bc37ee> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/State/b98c9> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/State/fc17f> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/State/d74f2> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/State/ebcc0> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/State/cebac> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/State/c3500> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/State/f8ff1> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/State/a52c1> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/State/c6bac> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/State/b3048> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Group/a605d> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/State/cd8fe> ;
        gpml:database     "Pubmed" ;
        gpml:id           "31695792" .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/f1772>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Group/d848a> ;
        gpml:align           "Center" ;
        gpml:centerX         "128.05770308299583"^^xsd:double ;
        gpml:centerY         "302.5407047387609"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "f1772" ;
        gpml:groupRef        "bc5eb" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "PIK3CG" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "70.0"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000105851" ;
        gpml:zorder          "32768"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id3fb4e606/Point/ad01556e22fd8d730757efe9c1139ee6>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id3fb4e606> ;
        gpml:graphRef     "af5e4" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "625.7372515125319"^^xsd:double ;
        gpml:y            "283.46822644770964"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/ideff6c101/Point/ad0a8dd1d07be4355687716a26e7b50b>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/ideff6c101> ;
        gpml:graphRef     "a29ba" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "438.12501889740867"^^xsd:double ;
        gpml:y            "579.6341241865046"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/State/ebab0>
        rdf:type            gpml:State ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:color          "0" ;
        gpml:fillColor      "ffffff" ;
        gpml:graphId        "ebab0" ;
        gpml:graphRef       "f46ee" ;
        gpml:hasComment     <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Comment/b1e04841cf8863e2da357146d5004da6> ;
        gpml:height         "15.0"^^xsd:double ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:relX           "0.9714285714285714"^^xsd:double ;
        gpml:relY           "0.8"^^xsd:double ;
        gpml:shapeType      "Oval" ;
        gpml:stateOf        <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/f46ee> ;
        gpml:stateType      "Unknown" ;
        gpml:textlabel      "P" ;
        gpml:width          "15.0"^^xsd:double ;
        gpml:zorder         "32860"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/f04f4>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:align           "Center" ;
        gpml:centerX         "438.9538770550739"^^xsd:double ;
        gpml:centerY         "639.0120485861415"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "f04f4" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "EIF4EBP1" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "80.0"^^xsd:double ;
        gpml:xrefDataSource  "Entrez Gene" ;
        gpml:xrefId          "1978" ;
        gpml:zorder          "33801"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/f4aa5>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Group/f77f0> ;
        gpml:align           "Center" ;
        gpml:centerX         "473.0656636373991"^^xsd:double ;
        gpml:centerY         "416.04153159391217"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "f4aa5" ;
        gpml:groupRef        "d4f15" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "TSC2" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "70.0"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000103197" ;
        gpml:zorder          "32854"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id6245b6cd>
        rdf:type                 gpml:Interaction ;
        dcterms:isPartOf         <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:biopaxRef           "f64" ;
        gpml:color               "0" ;
        gpml:connectorType       "Straight" ;
        gpml:graphId             "id6245b6cd" ;
        gpml:hasComment          <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Comment/da059327423c96c07771b5397ada36a8> ;
        gpml:hasPoint            <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id6245b6cd/Point/f2f2bb41b7931e514f432fde09f78ae4> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id6245b6cd/Point/ba25feaa2387d0f3494dfcae9eb6e61c> ;
        gpml:hasPublicationXref  <http://rdf.wikipathways.org/Pathway/WP4674_r142545/pub/f64> ;
        gpml:lineStyle           "Solid" ;
        gpml:lineThickness       "1.0"^^xsd:double ;
        gpml:zorder              "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/GraphicalLine/c337b>
        rdf:type            gpml:GraphicalLine ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "c337b" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP4674_r142545/GraphicalLine/c337b/Point/7515af1d84a1f5d6a81ee53d81b7d79b> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/GraphicalLine/c337b/Point/3729570be6fe49eea38cd00eedc87bb6> ;
        gpml:lineStyle      "Broken" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "32883"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Group/f77f0>
        rdf:type          gpml:Group ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:graphId      "f77f0" ;
        gpml:groupId      "d4f15" ;
        gpml:style        "Complex" .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/c2075>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Group/af5e4> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:align           "Center" ;
        gpml:centerX         "708.6633535004322"^^xsd:double ;
        gpml:centerY         "253.4684528954192"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "c2075" ;
        gpml:groupRef        "cdbf1" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "NFKB1" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "70.0"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000109320" ;
        gpml:zorder          "33829"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/GraphicalLine/ab138>
        rdf:type            gpml:GraphicalLine ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:color          "0" ;
        gpml:connectorType  "Elbow" ;
        gpml:graphId        "ab138" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP4674_r142545/GraphicalLine/ab138/Point/7b3f60d288d593108007b5b8fa147342> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/GraphicalLine/ab138/Point/710f88eda7e56e31c9ae87fa155d7ca6> ;
        gpml:lineStyle      "Broken" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "32871"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/State/e332d>
        rdf:type            gpml:State ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:color          "0" ;
        gpml:fillColor      "ffffff" ;
        gpml:graphId        "e332d" ;
        gpml:graphRef       "f46ee" ;
        gpml:hasComment     <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Comment/cdf055ae6c883a3e07a76136388e8de1> ;
        gpml:height         "15.0"^^xsd:double ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:relX           "-1.0"^^xsd:double ;
        gpml:relY           "0.8"^^xsd:double ;
        gpml:shapeType      "Oval" ;
        gpml:stateOf        <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/f46ee> ;
        gpml:stateType      "Unknown" ;
        gpml:textlabel      "P" ;
        gpml:width          "15.0"^^xsd:double ;
        gpml:zorder         "32860"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/a34d9>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Group/f77f0> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:align           "Center" ;
        gpml:centerX         "403.0656636373991"^^xsd:double ;
        gpml:centerY         "416.04153159391217"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "a34d9" ;
        gpml:groupRef        "d4f15" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "TSC1" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "70.0"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000165699" ;
        gpml:zorder          "32853"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/a1b32>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Group/deb35> ;
        gpml:align           "Center" ;
        gpml:centerX         "599.2717750826902"^^xsd:double ;
        gpml:centerY         "573.6758544652702"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "a1b32" ;
        gpml:groupRef        "e2a6a" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "FKBP1A" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "73.66593164277835"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000088832" ;
        gpml:zorder          "32768"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/cf932>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:align           "Center" ;
        gpml:centerX         "487.9668457046315"^^xsd:double ;
        gpml:centerY         "901.6088769028619"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "cf932" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "CASP8" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "70.0"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000064012" ;
        gpml:zorder          "32768"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Comment/a19efe25899bf1edb6fb2d25b8a27870>
        rdf:type          gpml:Comment ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545/State/afb39> ;
        gpml:commentText  "parentid=P49815; parentsymbol=TSC2; site=sFRARstsLNERPKs; position=ser939; sitegrpid=448501; ptm=p; direction=d" .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/State/e4fa1>
        rdf:type            gpml:State ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:color          "0" ;
        gpml:fillColor      "ffffff" ;
        gpml:graphId        "e4fa1" ;
        gpml:graphRef       "b1a41" ;
        gpml:height         "15.0"^^xsd:double ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:relX           "-0.9428571428571428"^^xsd:double ;
        gpml:relY           "-0.9"^^xsd:double ;
        gpml:shapeType      "Triangle" ;
        gpml:stateOf        <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/b1a41> ;
        gpml:stateType      "Unknown" ;
        gpml:textlabel      "" ;
        gpml:width          "15.0"^^xsd:double ;
        gpml:zorder         "33819"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id19ff6cd6>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "id19ff6cd6" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id19ff6cd6/Point/a4350e27909f448c9c4d7ac14ce64985> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id19ff6cd6/Point/88cf3bbafe1c06a7e51e7d8be6f42a66> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/fc7b8>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:align           "Center" ;
        gpml:centerX         "272.39368165249095"^^xsd:double ;
        gpml:centerY         "313.42244243122514"^^xsd:double ;
        gpml:color           "ff" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "fc7b8" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "PI3K inhibitors" ;
        gpml:type            "Metabolite" ;
        gpml:valign          "Middle" ;
        gpml:width           "90.0"^^xsd:double ;
        gpml:xrefDataSource  "ChEBI" ;
        gpml:xrefId          "CHEBI:50914" ;
        gpml:zorder          "32768"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/idd374a88/Point/e3ddace8e51c543ec99017404c485ac3>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/idd374a88> ;
        gpml:graphRef     "f595e" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "163.00929705407708"^^xsd:double ;
        gpml:y            "416.04153159391217"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id1209ef14/Point/c4d2ad759ecf56da6b37ee1eea21afee>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id1209ef14> ;
        gpml:graphRef     "ee18e" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "392.9108955637061"^^xsd:double ;
        gpml:y            "849.7230517595494"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id7171d355>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:color          "0" ;
        gpml:connectorType  "Elbow" ;
        gpml:graphId        "id7171d355" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id7171d355/Point/f512247ccea238e9dde9cac0b131f28e> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id7171d355/Point/a9ae11b97d40ed5e22759c23f4edcfab> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/State/c6bac>
        rdf:type                 gpml:State ;
        dcterms:isPartOf         <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:biopaxRef           "fb2" ;
        gpml:color               "0" ;
        gpml:fillColor           "ffffff" ;
        gpml:graphId             "c6bac" ;
        gpml:graphRef            "b92bc" ;
        gpml:hasPublicationXref  <https://identifiers.org/pubmed/31695792> ;
        gpml:height              "15.0"^^xsd:double ;
        gpml:lineStyle           "Solid" ;
        gpml:lineThickness       "1.0"^^xsd:double ;
        gpml:relX                "-0.9818181818181821"^^xsd:double ;
        gpml:relY                "-0.8"^^xsd:double ;
        gpml:shapeType           "Triangle" ;
        gpml:stateOf             <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/b92bc> ;
        gpml:stateType           "Unknown" ;
        gpml:textlabel           "" ;
        gpml:width               "15.0"^^xsd:double ;
        gpml:zorder              "32831"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id2015c60/Point/6b1dd93a21aa65c009871bf4f848afce>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id2015c60> ;
        gpml:graphRef     "f77f0" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "356.0656636373991"^^xsd:double ;
        gpml:y            "416.04153159391217"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Group/fe6d3>
        rdf:type          gpml:Group ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:graphId      "fe6d3" ;
        gpml:groupId      "a3124" ;
        gpml:style        "Complex" .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id60dbd269>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:color          "0" ;
        gpml:connectorType  "Elbow" ;
        gpml:graphId        "id60dbd269" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id60dbd269/Point/968757e91fbdf8af9d64ef142ed2c59a> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id60dbd269/Point/b931b1f07f47c508ff4dacff8b02b0d3> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id60dbd269/Point/b931b1f07f47c508ff4dacff8b02b0d3>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id60dbd269> ;
        gpml:graphRef     "b23bb" ;
        gpml:relX         "1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "662.7818147352465"^^xsd:double ;
        gpml:y            "1003.3441734417357"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/f82c2>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Group/c390f> ;
        gpml:align           "Center" ;
        gpml:centerX         "307.08655714674995"^^xsd:double ;
        gpml:centerY         "788.9423314181419"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "f82c2" ;
        gpml:groupRef        "f9985" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "SESN1" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "70.0"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000080546" ;
        gpml:zorder          "32867"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/idee431d35/Point/a3e7d22053fc17c85aa7b2bc9ccbdfcd>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/idee431d35> ;
        gpml:graphRef     "d6359" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "627.9337680621923"^^xsd:double ;
        gpml:y            "850.1733231913108"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/c94ca/Point/5fc3205c503f279d6c0a5a9c028305f2>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/c94ca> ;
        gpml:graphRef     "d2be7" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "438.0656636373991"^^xsd:double ;
        gpml:y            "243.12679162072772"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id62611738/Point/8ca3ff53bd86da17111fc88ef0ec3507>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id62611738> ;
        gpml:graphRef     "b9db3" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "534.8636368750282"^^xsd:double ;
        gpml:y            "675.1468160865431"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/idd2351f46>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:color          "0" ;
        gpml:connectorType  "Elbow" ;
        gpml:graphId        "idd2351f46" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/idd2351f46/Point/b63eb8419fffb1fa34e821416f520dba> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/idd2351f46/Point/b7d647cb0653648e878572c4629797a0> ;
        gpml:lineStyle      "Broken" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/GraphicalLine/f49d4>
        rdf:type            gpml:GraphicalLine ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "f49d4" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP4674_r142545/GraphicalLine/f49d4/Point/38d03f8d640090ac518e5b9bd78a7831> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/GraphicalLine/f49d4/Point/e635f07e70e6bd96a540d7ece4427d6e> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id2db3d091/Point/1a912f3fb4b8c26812a91b0ddbb1556b>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id2db3d091> ;
        gpml:graphRef     "e1aa5" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "627.7818147352465"^^xsd:double ;
        gpml:y            "910.8780487804868"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Group/d848a>
        rdf:type          gpml:Group ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:graphId      "d848a" ;
        gpml:groupId      "bc5eb" ;
        gpml:style        "Complex" .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id9cf21b4e/Point/1a89aff912a593bda95f7bebfbc9403f>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id9cf21b4e> ;
        gpml:graphRef     "b781d" ;
        gpml:relX         "-0.5"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "983.7586290699271"^^xsd:double ;
        gpml:y            "836.7750697521741"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/State/f6d86>
        rdf:type            gpml:State ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:color          "0" ;
        gpml:fillColor      "ffffff" ;
        gpml:graphId        "f6d86" ;
        gpml:graphRef       "f7569" ;
        gpml:height         "15.0"^^xsd:double ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:relX           "-1.0"^^xsd:double ;
        gpml:relY           "-0.9047619047618991"^^xsd:double ;
        gpml:shapeType      "Hexagon" ;
        gpml:stateOf        <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/f7569> ;
        gpml:stateType      "Unknown" ;
        gpml:textlabel      "" ;
        gpml:width          "15.0"^^xsd:double ;
        gpml:zorder         "32769"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Comment/55337c20cbd17306e7e50da65abbe726>
        rdf:type          gpml:Comment ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545/State/e57cc> ;
        gpml:commentText  "parentid=P62753; parentsymbol=RPS6; site=AKRRRLssLRAstsK; position=ser236; sitegrpid=448093; ptm=p; direction=u" .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/GraphicalLine/ab138/Point/7b3f60d288d593108007b5b8fa147342>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/GraphicalLine/ab138> ;
        gpml:graphRef     "ddc68" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "304.449227235615"^^xsd:double ;
        gpml:y            "1072.1891124743595"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id29256dcf/Anchor/c2e1e>
        rdf:type          gpml:Anchor ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id29256dcf> ;
        gpml:graphId      "c2e1e" ;
        gpml:position     "0.4"^^xsd:double ;
        gpml:shape        "None" .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/ef180>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Group/a605d> ;
        gpml:align           "Center" ;
        gpml:centerX         "273.7567786865869"^^xsd:double ;
        gpml:centerY         "67.18166472310352"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "ef180" ;
        gpml:groupRef        "e045b" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "FGFR1" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "70.0"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000077782" ;
        gpml:zorder          "33821"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/fbf7f>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:align           "Center" ;
        gpml:centerX         "668.6245638254369"^^xsd:double ;
        gpml:centerY         "193.1301296992832"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "fbf7f" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "CASP8" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "70.0"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000064012" ;
        gpml:zorder          "33824"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id793259d9/Point/8aede580e571abbe2daeffe3b52bc571>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id793259d9> ;
        gpml:graphRef     "f688a" ;
        gpml:relX         "0.5"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "155.83843388588383"^^xsd:double ;
        gpml:y            "859.7230517595494"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Comment/96efaa6b03219586a79a456bf96a015d>
        rdf:type          gpml:Comment ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545/State/dc67d> ;
        gpml:commentText  "parentid=P31749; parentsymbol=AKT1; site=RPHFPQFsysAsGtA; position=ser473; sitegrpid=447855; ptm=p; direction=u" .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id4ff3e838/Point/5ceef0c2a21c2121de8aebd5da5dc62c>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id4ff3e838> ;
        gpml:graphRef     "af357" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "438.7518436638353"^^xsd:double ;
        gpml:y            "675.1468160865431"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Group/af5e4>
        rdf:type          gpml:Group ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:graphId      "af5e4" ;
        gpml:groupId      "cdbf1" ;
        gpml:style        "Complex" .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/State/ccaa9>
        rdf:type            gpml:State ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:color          "0" ;
        gpml:fillColor      "ffffff" ;
        gpml:graphId        "ccaa9" ;
        gpml:graphRef       "f04f4" ;
        gpml:hasComment     <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Comment/a9dd498245a62c89cfc748e79106961d> ;
        gpml:height         "15.0"^^xsd:double ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:relX           "1.0"^^xsd:double ;
        gpml:relY           "-0.8972053462940494"^^xsd:double ;
        gpml:shapeType      "Oval" ;
        gpml:stateOf        <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/f04f4> ;
        gpml:stateType      "Unknown" ;
        gpml:textlabel      "P" ;
        gpml:width          "15.0"^^xsd:double ;
        gpml:zorder         "33802"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id93942fc8>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:color          "0" ;
        gpml:connectorType  "Elbow" ;
        gpml:graphId        "id93942fc8" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id93942fc8/Point/4e40f3e087731a2a2feb4ee9a032e2f1> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id93942fc8/Point/97e28d59512080ae4890e7c7bef1c3eb> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/GraphicalLine/dc46f/Point/9bf67bd7ce45c4f723df9f62052cc232>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/GraphicalLine/dc46f> ;
        gpml:graphRef     "fe637" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "589.1287970838346"^^xsd:double ;
        gpml:y            "613.6166306763446"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/State/a52c1>
        rdf:type                 gpml:State ;
        dcterms:isPartOf         <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:biopaxRef           "fb2" ;
        gpml:color               "0" ;
        gpml:fillColor           "ffffff" ;
        gpml:graphId             "a52c1" ;
        gpml:graphRef            "e2132" ;
        gpml:hasPublicationXref  <https://identifiers.org/pubmed/31695792> ;
        gpml:height              "15.0"^^xsd:double ;
        gpml:lineStyle           "Solid" ;
        gpml:lineThickness       "1.0"^^xsd:double ;
        gpml:relX                "-0.9856163885996854"^^xsd:double ;
        gpml:relY                "-0.772525849335301"^^xsd:double ;
        gpml:shapeType           "Hexagon" ;
        gpml:stateOf             <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/e2132> ;
        gpml:stateType           "Unknown" ;
        gpml:textlabel           "" ;
        gpml:width               "15.0"^^xsd:double ;
        gpml:zorder              "32769"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/f8503>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:align           "Center" ;
        gpml:centerX         "948.168803418803"^^xsd:double ;
        gpml:centerY         "785.4414081733131"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "f8503" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "MAML1" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "70.0"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000161021" ;
        gpml:zorder          "32768"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Label/f93a1>
        rdf:type             gpml:Label ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:align           "Center" ;
        gpml:centerX         "1114.9520048602662"^^xsd:double ;
        gpml:centerY         "898.3701824908654"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Bold" ;
        gpml:graphId         "f93a1" ;
        gpml:height          "47.00123080603635"^^xsd:double ;
        gpml:href            "" ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "None" ;
        gpml:textlabel       "Inflammation\nAngiogenesis\nMigration" ;
        gpml:valign          "Middle" ;
        gpml:width           "92.09599027946751"^^xsd:double ;
        gpml:zorder          "33834"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id42078bd4/Point/c36eb8716848fc441a93dd82b326bdc1>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id42078bd4> ;
        gpml:graphRef     "efff3" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "1265.3205128205157"^^xsd:double ;
        gpml:y            "198.38461538461502"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/State/f7b58>
        rdf:type            gpml:State ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:color          "0" ;
        gpml:fillColor      "ffffff" ;
        gpml:graphId        "f7b58" ;
        gpml:graphRef       "f567f" ;
        gpml:height         "15.0"^^xsd:double ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:relX           "-1.0"^^xsd:double ;
        gpml:relY           "-0.9"^^xsd:double ;
        gpml:shapeType      "Hexagon" ;
        gpml:stateOf        <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/f567f> ;
        gpml:stateType      "Unknown" ;
        gpml:textlabel      "" ;
        gpml:width          "15.0"^^xsd:double ;
        gpml:zorder         "32879"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id93942fc8/Point/97e28d59512080ae4890e7c7bef1c3eb>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id93942fc8> ;
        gpml:graphRef     "f0d17" ;
        gpml:relX         "1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "662.5583232077771"^^xsd:double ;
        gpml:y            "1048.2855407047414"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Comment/1fcaa3bf37716a9324de689ffcb180bf>
        rdf:type          gpml:Comment ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545/State/b8efe> ;
        gpml:commentText  "parentid=P31749; parentsymbol=AKT1; site=kDGAtMKtFCGtPEy; position=thr308; sitegrpid=447856; ptm=p; direction=u" .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/idacd50709/Point/57f14fcdd506ca8d6e8b22de89eda141>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/idacd50709> ;
        gpml:graphRef     "b23bb" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "627.7818147352465"^^xsd:double ;
        gpml:y            "993.3441734417357"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id85e33a01/Point/7152a79482257e21237e8d61557e9b30>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id85e33a01> ;
        gpml:graphRef     "d0dfd" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "120.95239702885664"^^xsd:double ;
        gpml:y            "790.8817502340637"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id9196c758>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "id9196c758" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id9196c758/Point/eb616685ae4f57f716983ab20e47477d> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id9196c758/Point/9032752900f9db0f4a74383fa542374e> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/State/afb39>
        rdf:type                 gpml:State ;
        dcterms:isPartOf         <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:biopaxRef           "d41" ;
        gpml:color               "0" ;
        gpml:fillColor           "ffffff" ;
        gpml:graphId             "afb39" ;
        gpml:graphRef            "f4aa5" ;
        gpml:hasComment          <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Comment/a19efe25899bf1edb6fb2d25b8a27870> ;
        gpml:hasPublicationXref  <https://identifiers.org/pubmed/12150915> ;
        gpml:height              "15.0"^^xsd:double ;
        gpml:lineStyle           "Solid" ;
        gpml:lineThickness       "1.0"^^xsd:double ;
        gpml:relX                "1.0"^^xsd:double ;
        gpml:relY                "0.8"^^xsd:double ;
        gpml:shapeType           "Oval" ;
        gpml:stateOf             <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/f4aa5> ;
        gpml:stateType           "Unknown" ;
        gpml:textlabel           "P" ;
        gpml:width               "15.0"^^xsd:double ;
        gpml:zorder              "32855"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/idc4bc37ee/Point/3dc5b9917a09fe041b6899e1b07a3f8c>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/idc4bc37ee> ;
        gpml:graphRef     "efff3" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "1230.3205128205157"^^xsd:double ;
        gpml:y            "208.38461538461502"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/e2a5f/Point/208d0125106258e11efa07bac649fe7d>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/e2a5f> ;
        gpml:graphRef     "a3aed" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "502.65720111298504"^^xsd:double ;
        gpml:y            "233.12679162072772"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/State/fc5e0>
        rdf:type                 gpml:State ;
        dcterms:isPartOf         <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:biopaxRef           "fb2" ;
        gpml:color               "0" ;
        gpml:fillColor           "ffffff" ;
        gpml:graphId             "fc5e0" ;
        gpml:graphRef            "bb45e" ;
        gpml:hasPublicationXref  <https://identifiers.org/pubmed/31695792> ;
        gpml:height              "15.0"^^xsd:double ;
        gpml:lineStyle           "Solid" ;
        gpml:lineThickness       "1.0"^^xsd:double ;
        gpml:relX                "-0.9692941782586296"^^xsd:double ;
        gpml:relY                "-0.84"^^xsd:double ;
        gpml:shapeType           "Hexagon" ;
        gpml:stateOf             <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/bb45e> ;
        gpml:stateType           "Unknown" ;
        gpml:textlabel           "" ;
        gpml:width               "15.0"^^xsd:double ;
        gpml:zorder              "33824"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/e4b3f>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "e4b3f" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/e4b3f/Point/6c558ad2c72f8667c4cebb1ac4a8b5f8> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/e4b3f/Point/a592417ca3fa77732205ea195ffdbf88> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "32864"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/dea8b>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:align           "Center" ;
        gpml:centerX         "816.8339400633806"^^xsd:double ;
        gpml:centerY         "872.0486340716812"^^xsd:double ;
        gpml:color           "ff6600" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "dea8b" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "HPV E7" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "70.0"^^xsd:double ;
        gpml:xrefDataSource  "" ;
        gpml:xrefId          "" ;
        gpml:zorder          "32870"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/State/b98c9>
        rdf:type                 gpml:State ;
        dcterms:isPartOf         <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:biopaxRef           "fb2" ;
        gpml:color               "0" ;
        gpml:fillColor           "ffffff" ;
        gpml:graphId             "b98c9" ;
        gpml:graphRef            "cee2e" ;
        gpml:hasPublicationXref  <https://identifiers.org/pubmed/31695792> ;
        gpml:height              "15.0"^^xsd:double ;
        gpml:lineStyle           "Solid" ;
        gpml:lineThickness       "1.0"^^xsd:double ;
        gpml:relX                "-0.9001936558236432"^^xsd:double ;
        gpml:relY                "-1.0"^^xsd:double ;
        gpml:shapeType           "Triangle" ;
        gpml:stateOf             <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/cee2e> ;
        gpml:stateType           "Unknown" ;
        gpml:textlabel           "" ;
        gpml:width               "15.0"^^xsd:double ;
        gpml:zorder              "32870"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Label/af03a>
        rdf:type             gpml:Label ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:align           "Center" ;
        gpml:centerX         "867.3232077764277"^^xsd:double ;
        gpml:centerY         "787.8173349534219"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Bold" ;
        gpml:graphId         "af03a" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:href            "" ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "None" ;
        gpml:textlabel       "Survival" ;
        gpml:valign          "Middle" ;
        gpml:width           "90.0"^^xsd:double ;
        gpml:zorder          "28672"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Comment/bd45ca0c649604c5d22f5e4969f510c1>
        rdf:type          gpml:Comment ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545/State/b6956> ;
        gpml:commentText  "parentid=P62753; parentsymbol=RPS6; site=IAKRRRLssLRAsts; position=ser235; sitegrpid=448092; ptm=p; direction=u" .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/cee2e>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:align           "Center" ;
        gpml:centerX         "752.3985917442304"^^xsd:double ;
        gpml:centerY         "936.2093093511317"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "cee2e" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "CCND1" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "70.0"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000110092" ;
        gpml:zorder          "32869"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id907c03df>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "id907c03df" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id907c03df/Point/33871990b37b475c6f81354bdf0d7767> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id907c03df/Point/5ec1b9e00c629230fd4baa06ee60134> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id42078bd4>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "id42078bd4" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id42078bd4/Point/c36eb8716848fc441a93dd82b326bdc1> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id42078bd4/Point/86fe90a2db0ac9ab1875e2e04230639a> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/idb1cc7053>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:color          "0" ;
        gpml:connectorType  "Elbow" ;
        gpml:graphId        "idb1cc7053" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/idb1cc7053/Point/527d8b00dde224f736c3269f29310bd7> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/idb1cc7053/Point/208539f2b1c4761ab8154d22d755a5d3> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/idb1cc7053/Point/7fad32e4f99aea430446836b505aa6f5> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/GraphicalLine/fb4a2/Point/271695e7904bf2376300cf548f6c56b3>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/GraphicalLine/fb4a2> ;
        gpml:graphRef     "ddb33" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "1111.850974386676"^^xsd:double ;
        gpml:y            "281.78578958105675"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Comment/ce83605bac3f42ab9d91267d3d9e4b1b>
        rdf:type          gpml:Comment ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545/State/c595d> ;
        gpml:commentText  "parentid=Q13541; parentsymbol=EIF4EBP1; site=GGtLFsttPGGtRII; position=thr46; sitegrpid=447496; ptm=p; direction=d" .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Label/ddb33>
        rdf:type             gpml:Label ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:align           "Center" ;
        gpml:centerX         "1111.850974386676"^^xsd:double ;
        gpml:centerY         "294.94582438186285"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Bold" ;
        gpml:graphId         "ddb33" ;
        gpml:height          "26.320069601612197"^^xsd:double ;
        gpml:href            "" ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "None" ;
        gpml:textlabel       "Differentiation" ;
        gpml:valign          "Middle" ;
        gpml:width           "91.17253948967164"^^xsd:double ;
        gpml:zorder          "32875"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id5ef1a8e/Point/516873610703e3182bf645ec4b68a39e>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id5ef1a8e> ;
        gpml:graphRef     "b23bb" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "627.7818147352465"^^xsd:double ;
        gpml:y            "1013.3441734417357"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id85e33a01>
        rdf:type                 gpml:Interaction ;
        dcterms:isPartOf         <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:biopaxRef           "c69" ;
        gpml:color               "0" ;
        gpml:connectorType       "Straight" ;
        gpml:graphId             "id85e33a01" ;
        gpml:hasPoint            <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id85e33a01/Point/7152a79482257e21237e8d61557e9b30> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id85e33a01/Point/d19a93ec7d3c4d913c73e2957db65807> ;
        gpml:hasPublicationXref  <http://rdf.wikipathways.org/Pathway/WP4674_r142545/pub/c69> ;
        gpml:lineStyle           "Solid" ;
        gpml:lineThickness       "1.0"^^xsd:double ;
        gpml:zorder              "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/State/fc17f>
        rdf:type                 gpml:State ;
        dcterms:isPartOf         <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:biopaxRef           "fb2" ;
        gpml:color               "0" ;
        gpml:fillColor           "ffffff" ;
        gpml:graphId             "fc17f" ;
        gpml:graphRef            "b23bb" ;
        gpml:hasPublicationXref  <https://identifiers.org/pubmed/31695792> ;
        gpml:height              "15.0"^^xsd:double ;
        gpml:lineStyle           "Solid" ;
        gpml:lineThickness       "1.0"^^xsd:double ;
        gpml:relX                "-0.940530879815132"^^xsd:double ;
        gpml:relY                "-0.7496962332928342"^^xsd:double ;
        gpml:shapeType           "Hexagon" ;
        gpml:stateOf             <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/b23bb> ;
        gpml:stateType           "Unknown" ;
        gpml:textlabel           "" ;
        gpml:width               "15.0"^^xsd:double ;
        gpml:zorder              "32769"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/d9e82>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Group/a29ba> ;
        gpml:align           "Center" ;
        gpml:centerX         "406.4722600170394"^^xsd:double ;
        gpml:centerY         "536.9119019642817"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "d9e82" ;
        gpml:groupRef        "f1cb3" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "RPTOR" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "70.0"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000141564" ;
        gpml:zorder          "32860"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/GraphicalLine/dc46f/Point/55fe805733d1babd849fcdaaee5e783a>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/GraphicalLine/dc46f> ;
        gpml:graphRef     "a29ba" ;
        gpml:relX         "0.5"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "477.45139833759333"^^xsd:double ;
        gpml:y            "579.6341241865046"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/f29db/Point/99649d0460d560e49d26cf1c8914d978>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/f29db> ;
        gpml:graphRef     "e8b0f" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "668.6245638254368"^^xsd:double ;
        gpml:y            "131.5234899328859"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Comment/88550acc9f7e98cf85110ea3630f4389>
        rdf:type          gpml:Comment ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545/State/a0f1f> ;
        gpml:commentText  "parentid=Q13541; parentsymbol=EIF4EBP1; site=FLMECrNsPVtktPP; position=ser65; sitegrpid=447527; ptm=p; direction=d" .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id18d2fa71>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "id18d2fa71" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id18d2fa71/Point/398abce50fb957bd1fe8b67cfbe1de98> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id18d2fa71/Point/80791bcf21e28ae5e9a0f157c6c6bc21> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Label/f35e2>
        rdf:type             gpml:Label ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:align           "Center" ;
        gpml:centerX         "878.5"^^xsd:double ;
        gpml:centerY         "283.4993845969818"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Bold" ;
        gpml:graphId         "f35e2" ;
        gpml:height          "47.00123080603635"^^xsd:double ;
        gpml:href            "" ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "None" ;
        gpml:textlabel       "Inflammation\nAngiogenesis\nMigration" ;
        gpml:valign          "Middle" ;
        gpml:width           "99.0"^^xsd:double ;
        gpml:zorder          "33833"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/State/b6956>
        rdf:type            gpml:State ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:color          "0" ;
        gpml:fillColor      "ffffff" ;
        gpml:graphId        "b6956" ;
        gpml:graphRef       "b9db3" ;
        gpml:hasComment     <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Comment/bd45ca0c649604c5d22f5e4969f510c1> ;
        gpml:height         "15.0"^^xsd:double ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:relX           "-0.9702925522663304"^^xsd:double ;
        gpml:relY           "-0.906432748538009"^^xsd:double ;
        gpml:shapeType      "Oval" ;
        gpml:stateOf        <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/b9db3> ;
        gpml:stateType      "Unknown" ;
        gpml:textlabel      "P" ;
        gpml:width          "15.0"^^xsd:double ;
        gpml:zorder         "32866"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/idb1cc7053/Point/527d8b00dde224f736c3269f29310bd7>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/idb1cc7053> ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "1179.0"^^xsd:double ;
        gpml:y            "949.4820911132667"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/f567f>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Group/f6641> ;
        gpml:align           "Center" ;
        gpml:centerX         "1078.3111194707603"^^xsd:double ;
        gpml:centerY         "406.90145956006603"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "f567f" ;
        gpml:groupRef        "b44cf" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "TGFBR2" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "70.0"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000163513" ;
        gpml:zorder          "32878"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/f5e0d>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Group/a605d> ;
        gpml:align           "Center" ;
        gpml:centerX         "424.0584903814008"^^xsd:double ;
        gpml:centerY         "67.18166472310354"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "f5e0d" ;
        gpml:groupRef        "e045b" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "IGF1R" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "70.0"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000140443" ;
        gpml:zorder          "33819"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/cbf1c/Point/e3a80e7407c79eb519045f7b297af109>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/cbf1c> ;
        gpml:graphRef     "af5e4" ;
        gpml:relX         "0.5"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "756.0269014693172"^^xsd:double ;
        gpml:y            "231.46845289541923"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/State/f2e55>
        rdf:type            gpml:State ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:color          "0" ;
        gpml:fillColor      "ffffff" ;
        gpml:graphId        "f2e55" ;
        gpml:graphRef       "f5e0d" ;
        gpml:height         "15.0"^^xsd:double ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:relX           "-0.9142857142857143"^^xsd:double ;
        gpml:relY           "-1.0"^^xsd:double ;
        gpml:shapeType      "Triangle" ;
        gpml:stateOf        <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/f5e0d> ;
        gpml:stateType      "Unknown" ;
        gpml:textlabel      "" ;
        gpml:width          "15.0"^^xsd:double ;
        gpml:zorder         "33820"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/GraphicalLine/f2390/Point/e571d135b8fa84c46b7980db0b905784>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/GraphicalLine/f2390> ;
        gpml:graphRef     "b781d" ;
        gpml:relX         "0.5"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "1018.7586290699271"^^xsd:double ;
        gpml:y            "836.7750697521741"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/InfoBox/2a4f77e4e245114466ee6f63d4542f32>
        rdf:type          gpml:InfoBox ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:centerX      "0.0"^^xsd:double ;
        gpml:centerY      "0.0"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/GraphicalLine/fb4a2>
        rdf:type            gpml:GraphicalLine ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "fb4a2" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP4674_r142545/GraphicalLine/fb4a2/Point/271695e7904bf2376300cf548f6c56b3> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/GraphicalLine/fb4a2/Point/ce9e773ec52ec66a099053cc62abee88> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/State/dc67d>
        rdf:type            gpml:State ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:color          "0" ;
        gpml:fillColor      "ffffff" ;
        gpml:graphId        "dc67d" ;
        gpml:graphRef       "b0ab3" ;
        gpml:hasComment     <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Comment/96efaa6b03219586a79a456bf96a015d> ;
        gpml:height         "15.0"^^xsd:double ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:relX           "0.8571428571428571"^^xsd:double ;
        gpml:relY           "-1.0"^^xsd:double ;
        gpml:shapeType      "Oval" ;
        gpml:stateOf        <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/b0ab3> ;
        gpml:stateType      "Unknown" ;
        gpml:textlabel      "P" ;
        gpml:width          "15.0"^^xsd:double ;
        gpml:zorder         "32823"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Comment/2f0f7784c90e418e6f6ee76ee212080d>
        rdf:type          gpml:Comment ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545/State/e8abd> ;
        gpml:commentText  "parentid=Q9Y243; parentsymbol=AKT3; site=tDAATMKtFCGtPEy; position=thr305; sitegrpid=448521; ptm=p; direction=u" .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id960f1d40/Point/fd0d9312a9d5e5bf203a70c04fd8e06e>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id960f1d40> ;
        gpml:graphRef     "a29ba" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "438.12501889740867"^^xsd:double ;
        gpml:y            "514.6944444444453"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/State/b8efe>
        rdf:type            gpml:State ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:color          "0" ;
        gpml:fillColor      "ffffff" ;
        gpml:graphId        "b8efe" ;
        gpml:graphRef       "b0ab3" ;
        gpml:hasComment     <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Comment/1fcaa3bf37716a9324de689ffcb180bf> ;
        gpml:height         "15.0"^^xsd:double ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:relX           "0.8571428571428571"^^xsd:double ;
        gpml:relY           "0.7"^^xsd:double ;
        gpml:shapeType      "Oval" ;
        gpml:stateOf        <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/b0ab3> ;
        gpml:stateType      "Unknown" ;
        gpml:textlabel      "P" ;
        gpml:width          "15.0"^^xsd:double ;
        gpml:zorder         "32823"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/cbf1c>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "cbf1c" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/cbf1c/Point/17250b8b3c952c1b323bec85837b0910> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/cbf1c/Point/e3a80e7407c79eb519045f7b297af109> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "33826"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/State/cebac>
        rdf:type                 gpml:State ;
        dcterms:isPartOf         <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:biopaxRef           "fb2" ;
        gpml:color               "0" ;
        gpml:fillColor           "ffffff" ;
        gpml:graphId             "cebac" ;
        gpml:graphRef            "a3aed" ;
        gpml:hasPublicationXref  <https://identifiers.org/pubmed/31695792> ;
        gpml:height              "15.0"^^xsd:double ;
        gpml:lineStyle           "Solid" ;
        gpml:lineThickness       "1.0"^^xsd:double ;
        gpml:relX                "-1.0"^^xsd:double ;
        gpml:relY                "-1.0"^^xsd:double ;
        gpml:shapeType           "Hexagon" ;
        gpml:stateOf             <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/a3aed> ;
        gpml:stateType           "Unknown" ;
        gpml:textlabel           "" ;
        gpml:width               "15.0"^^xsd:double ;
        gpml:zorder              "32822"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Group/a6740>
        rdf:type          gpml:Group ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:graphId      "a6740" ;
        gpml:groupId      "eecd6" ;
        gpml:style        "Complex" .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id83f023a5/Point/2e5cd9a7156e1e6a79a03f17e9b7142d>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id83f023a5> ;
        gpml:graphRef     "b173b" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "442.9668457046315"^^xsd:double ;
        gpml:y            "951.8974964354733"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id85e33a01/Point/d19a93ec7d3c4d913c73e2957db65807>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id85e33a01> ;
        gpml:graphRef     "d8cd9" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "120.32653018240029"^^xsd:double ;
        gpml:y            "765.0108401084011"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/e4b3f/Point/6c558ad2c72f8667c4cebb1ac4a8b5f8>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/e4b3f> ;
        gpml:graphRef     "ee837" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "551.3582695582681"^^xsd:double ;
        gpml:y            "520.7755544041449"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Group/abf91>
        rdf:type          gpml:Group ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:graphId      "abf91" ;
        gpml:groupId      "d8b4d" ;
        gpml:style        "Complex" .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/f403a/Point/2909e53c5ea3132288d2229dd88555a1>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/f403a> ;
        gpml:graphRef     "e1afd" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "535.0473647131384"^^xsd:double ;
        gpml:y            "629.0120485861415"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Group/e2561>
        rdf:type          gpml:Group ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:graphId      "e2561" ;
        gpml:groupId      "bb289" ;
        gpml:style        "Complex" .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/cf704>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:align           "Center" ;
        gpml:centerX         "756.7013422818796"^^xsd:double ;
        gpml:centerY         "141.5234899328859"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "cf704" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "BIRC2" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "70.0"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000110330" ;
        gpml:zorder          "32768"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Label/f4221>
        rdf:type             gpml:Label ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:align           "Center" ;
        gpml:centerX         "1158.0668843620065"^^xsd:double ;
        gpml:centerY         "517.1265456829344"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Bold" ;
        gpml:graphId         "f4221" ;
        gpml:height          "17.951465201465908"^^xsd:double ;
        gpml:href            "" ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "None" ;
        gpml:textlabel       "Invasion and metastasis" ;
        gpml:valign          "Middle" ;
        gpml:width           "165.77106227106242"^^xsd:double ;
        gpml:zorder          "28672"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/e2a5f>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "e2a5f" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/e2a5f/Point/208d0125106258e11efa07bac649fe7d> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/e2a5f/Point/b1552b5c0cacf0dc36ddf328e0c0c2c3> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "32807"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/ee837>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:align           "Center" ;
        gpml:centerX         "603.9508621508608"^^xsd:double ;
        gpml:centerY         "520.7755544041449"^^xsd:double ;
        gpml:color           "ff" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "ee837" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "mTOR inhibitors" ;
        gpml:type            "Metabolite" ;
        gpml:valign          "Middle" ;
        gpml:width           "105.18518518518522"^^xsd:double ;
        gpml:xrefDataSource  "ChEBI" ;
        gpml:xrefId          "CHEBI:68481" ;
        gpml:zorder          "32768"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id951ee543>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:color          "0" ;
        gpml:connectorType  "Elbow" ;
        gpml:graphId        "id951ee543" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id951ee543/Point/7328bd1e9f8709580077cc0bb175f88> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id951ee543/Point/875afaf7aedf8d283a8c38a1169570bd> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Comment/cdf055ae6c883a3e07a76136388e8de1>
        rdf:type          gpml:Comment ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545/State/c28c5> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/State/e332d> ;
        gpml:commentText  "parentid=P42345; parentsymbol=MTOR; site=RsRtRtDsysAGQsV; position=ser2448; sitegrpid=447578; ptm=p; direction=u" .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/idb6f6ef82/Point/7c55d2922b1a9f2e6489b767aad604d6>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/idb6f6ef82> ;
        gpml:graphRef     "bd8fc" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "272.1130950434298"^^xsd:double ;
        gpml:y            "157.5234899328859"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/d2be7>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:align           "Center" ;
        gpml:centerX         "438.0656636373991"^^xsd:double ;
        gpml:centerY         "233.12679162072772"^^xsd:double ;
        gpml:color           "ff" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "d2be7" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "PIP3" ;
        gpml:type            "Metabolite" ;
        gpml:valign          "Middle" ;
        gpml:width           "70.0"^^xsd:double ;
        gpml:xrefDataSource  "ChEBI" ;
        gpml:xrefId          "CHEBI:16618" ;
        gpml:zorder          "32824"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/State/b3048>
        rdf:type                 gpml:State ;
        dcterms:isPartOf         <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:biopaxRef           "fb2" ;
        gpml:color               "0" ;
        gpml:fillColor           "ffffff" ;
        gpml:graphId             "b3048" ;
        gpml:graphRef            "b781d" ;
        gpml:hasPublicationXref  <https://identifiers.org/pubmed/31695792> ;
        gpml:height              "15.0"^^xsd:double ;
        gpml:lineStyle           "Solid" ;
        gpml:lineThickness       "1.0"^^xsd:double ;
        gpml:relX                "-0.9992003198720221"^^xsd:double ;
        gpml:relY                "-0.84281842818428"^^xsd:double ;
        gpml:shapeType           "Triangle" ;
        gpml:stateOf             <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/b781d> ;
        gpml:stateType           "Unknown" ;
        gpml:textlabel           "" ;
        gpml:width               "15.0"^^xsd:double ;
        gpml:zorder              "32769"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id3fb4e606/Point/6e0ca7dce00f3dc4a38beba61641ce7e>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id3fb4e606> ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "425.82860055649274"^^xsd:double ;
        gpml:y            "185.0"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/State/e9095>
        rdf:type                 gpml:State ;
        dcterms:isPartOf         <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:biopaxRef           "fb2" ;
        gpml:color               "0" ;
        gpml:fillColor           "ffffff" ;
        gpml:graphId             "e9095" ;
        gpml:graphRef            "e8b0f" ;
        gpml:hasPublicationXref  <https://identifiers.org/pubmed/31695792> ;
        gpml:height              "15.0"^^xsd:double ;
        gpml:lineStyle           "Solid" ;
        gpml:lineThickness       "1.0"^^xsd:double ;
        gpml:relX                "-0.9388516032811348"^^xsd:double ;
        gpml:relY                "-0.9181208053691264"^^xsd:double ;
        gpml:shapeType           "Triangle" ;
        gpml:stateOf             <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/e8b0f> ;
        gpml:stateType           "Unknown" ;
        gpml:textlabel           "" ;
        gpml:width               "15.0"^^xsd:double ;
        gpml:zorder              "32769"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id3c9c3b9f>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "id3c9c3b9f" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id3c9c3b9f/Point/337d092ad2f6d7d22089aaa2c12f3249> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id3c9c3b9f/Point/eeb1e2e4a33f742f4528a8868b2718d4> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id4552d5ec/Point/4b1eb853cb63ac2f8dcb5cd4cbae7a73>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id4552d5ec> ;
        gpml:graphRef     "deb35" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "554.438809261301"^^xsd:double ;
        gpml:y            "563.6758544652702"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/c3a2d>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Group/fe6d3> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:align           "Center" ;
        gpml:centerX         "731.966119000875"^^xsd:double ;
        gpml:centerY         "521.6785461147092"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "c3a2d" ;
        gpml:groupRef        "a3124" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "RICTOR" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "70.0"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000164327" ;
        gpml:zorder          "32768"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/c94ca>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "c94ca" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/c94ca/Point/5fc3205c503f279d6c0a5a9c028305f2> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/c94ca/Point/3c76226d8f5c65216944b93aafd7b741> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "32802"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/idee431d35/Point/dd8334cd1d031af5353fe7f83a97b48>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/idee431d35> ;
        gpml:graphRef     "b4b5d" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "628.5583232077777"^^xsd:double ;
        gpml:y            "818.4224382341012"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/ida8acd52d/Point/666f7bb88b4ed87d9cca63b8754df210>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/ida8acd52d> ;
        gpml:graphRef     "fbf7f" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "668.6245638254369"^^xsd:double ;
        gpml:y            "203.1301296992832"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id1209ef14>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "id1209ef14" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id1209ef14/Point/c4d2ad759ecf56da6b37ee1eea21afee> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id1209ef14/Point/dbe91860511544b264c1d84d6fb50503> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/State/a1e4d>
        rdf:type            gpml:State ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:color          "0" ;
        gpml:fillColor      "ffffff" ;
        gpml:graphId        "a1e4d" ;
        gpml:graphRef       "af720" ;
        gpml:hasComment     <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Comment/3d485485e980f91fe6fccd1d2cacc605> ;
        gpml:height         "15.0"^^xsd:double ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:relX           "-0.9428571428571428"^^xsd:double ;
        gpml:relY           "0.9"^^xsd:double ;
        gpml:shapeType      "Oval" ;
        gpml:stateOf        <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/af720> ;
        gpml:stateType      "Unknown" ;
        gpml:textlabel      "P" ;
        gpml:width          "15.0"^^xsd:double ;
        gpml:zorder         "32828"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id5178da0d/Point/25311b0161f70c572597424120ec6a8b>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id5178da0d> ;
        gpml:graphRef     "d1507" ;
        gpml:relX         "0.5"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "1017.6004273504259"^^xsd:double ;
        gpml:y            "80.5"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/GraphicalLine/dc46f>
        rdf:type            gpml:GraphicalLine ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "dc46f" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP4674_r142545/GraphicalLine/dc46f/Point/55fe805733d1babd849fcdaaee5e783a> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/GraphicalLine/dc46f/Point/9bf67bd7ce45c4f723df9f62052cc232> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Comment/67a17100ae5fef126b5b8677720452b0>
        rdf:type          gpml:Comment ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/e89aa> ;
        gpml:commentText  "c-Rel" ;
        gpml:source       "OCR" .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id3c9c3b9f/Point/337d092ad2f6d7d22089aaa2c12f3249>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id3c9c3b9f> ;
        gpml:graphRef     "bd8fc" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "272.1130950434298"^^xsd:double ;
        gpml:y            "121.5234899328859"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Group/bd8fc>
        rdf:type          gpml:Group ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:graphId      "bd8fc" ;
        gpml:groupId      "b61ea" ;
        gpml:style        "Group" .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id4552d5ec>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "id4552d5ec" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id4552d5ec/Point/51e8d45e729750a54d0c832a181c27d1> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id4552d5ec/Point/4b1eb853cb63ac2f8dcb5cd4cbae7a73> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/GraphicalLine/e46c9/Point/685b0be786de0f8b92430e687db6d510>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/GraphicalLine/e46c9> ;
        gpml:graphRef     "d8ba7" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "1158.392107235526"^^xsd:double ;
        gpml:y            "444.6097389275188"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/faa56>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "faa56" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/faa56/Point/2dca465a47fb23b864ac72e66129db43> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/faa56/Point/f16ec6e669d2f26e669a77b3bff76f5f> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "32803"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/GraphicalLine/ca171>
        rdf:type            gpml:GraphicalLine ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "ca171" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP4674_r142545/GraphicalLine/ca171/Point/539ba7f28e7bcfc5cb5bc2e5a11d8eb8> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/GraphicalLine/ca171/Point/b751a96fb41b6f4b620fc3628b98679b> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id7a37cac1/Point/d8d80f5acbf11e6a8ea6d2dbf4a4ee2c>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id7a37cac1> ;
        gpml:graphRef     "a1e2b" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "438.0656636373991"^^xsd:double ;
        gpml:y            "467.4119019642824"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/cc574>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Group/d848a> ;
        gpml:align           "Center" ;
        gpml:centerX         "128.05770308299589"^^xsd:double ;
        gpml:centerY         "322.5407047387609"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "cc574" ;
        gpml:groupRef        "bc5eb" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "PIK3R5" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "70.0"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000141506" ;
        gpml:zorder          "32768"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/State/e57cc>
        rdf:type            gpml:State ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:color          "0" ;
        gpml:fillColor      "ffffff" ;
        gpml:graphId        "e57cc" ;
        gpml:graphRef       "b9db3" ;
        gpml:hasComment     <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Comment/55337c20cbd17306e7e50da65abbe726> ;
        gpml:height         "15.0"^^xsd:double ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:relX           "1.0"^^xsd:double ;
        gpml:relY           "-0.906432748538009"^^xsd:double ;
        gpml:shapeType      "Oval" ;
        gpml:stateOf        <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/b9db3> ;
        gpml:stateType      "Unknown" ;
        gpml:textlabel      "P" ;
        gpml:width          "15.0"^^xsd:double ;
        gpml:zorder         "32866"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/d9f85>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Group/c8d56> ;
        gpml:align           "Center" ;
        gpml:centerX         "673.0"^^xsd:double ;
        gpml:centerY         "67.0"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "d9f85" ;
        gpml:groupRef        "ea664" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "LTBR" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "70.0"^^xsd:double ;
        gpml:xrefDataSource  "HGNC" ;
        gpml:xrefId          "LTBR" ;
        gpml:zorder          "33837"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id4e947078/Point/918f861f1c3347d20427d9a2c0367ccc>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id4e947078> ;
        gpml:graphRef     "fc7b8" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "227.39368165249095"^^xsd:double ;
        gpml:y            "313.42244243122514"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id4552d5ec/Point/51e8d45e729750a54d0c832a181c27d1>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id4552d5ec> ;
        gpml:graphRef     "a29ba" ;
        gpml:relX         "1.0"^^xsd:double ;
        gpml:relY         "0.5"^^xsd:double ;
        gpml:x            "516.7777777777779"^^xsd:double ;
        gpml:y            "563.3992042509897"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id62611738>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "id62611738" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id62611738/Point/8ca3ff53bd86da17111fc88ef0ec3507> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id62611738/Point/ebf9ad7d6116a6a33d8fdfd3e7e36035> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/ida0b85c43>
        rdf:type                 gpml:Interaction ;
        dcterms:isPartOf         <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:biopaxRef           "ff8" ;
        gpml:color               "0" ;
        gpml:connectorType       "Straight" ;
        gpml:graphId             "ida0b85c43" ;
        gpml:hasPoint            <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/ida0b85c43/Point/c46e86389e58d18d7f63b74dd307f6a0> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/ida0b85c43/Point/837fbb4c49d4ea36c04554afd80f3433> ;
        gpml:hasPublicationXref  <https://identifiers.org/pubmed/23847349> ;
        gpml:lineStyle           "Solid" ;
        gpml:lineThickness       "1.0"^^xsd:double ;
        gpml:zorder              "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/GraphicalLine/ca171/Point/b751a96fb41b6f4b620fc3628b98679b>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/GraphicalLine/ca171> ;
        gpml:graphRef     "a26ea" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "1264.5347350704367"^^xsd:double ;
        gpml:y            "311.29861009387736"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Shape/d30f7>
        rdf:type             gpml:shape ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:align           "Center" ;
        gpml:centerX         "673.5"^^xsd:double ;
        gpml:centerY         "911.751923855812"^^xsd:double ;
        gpml:color           "c0c0c0" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "d30f7" ;
        gpml:height          "384.4961522883759"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "3.0"^^xsd:double ;
        gpml:shape           "0.0"^^xsd:double ;
        gpml:shapeType       "RoundedRectangle" ;
        gpml:textlabel       "Nucleus" ;
        gpml:valign          "Bottom" ;
        gpml:width           "1211.0"^^xsd:double ;
        gpml:zorder          "16384"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/idff58edfc/Point/496c9a70aa63863d18ca0f8560f6d4c0>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/idff58edfc> ;
        gpml:graphRef     "c8d56" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "709.5"^^xsd:double ;
        gpml:y            "85.0"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/idef07ed1d>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "idef07ed1d" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/idef07ed1d/Point/1f9fffef059f3f24ac74c01aeb9bbdd2> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/idef07ed1d/Point/8f3edb2532090844199fa0bf509e6ca7> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/fac79>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Group/f595e> ;
        gpml:align           "Center" ;
        gpml:centerX         "210.00929705407708"^^xsd:double ;
        gpml:centerY         "416.04153159391217"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
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<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/idef07ed1d/Point/1f9fffef059f3f24ac74c01aeb9bbdd2>
        rdf:type          gpml:Point ;
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<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id60dbd269/Point/968757e91fbdf8af9d64ef142ed2c59a>
        rdf:type          gpml:Point ;
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<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id3cd48500/Point/b620cf0922c5c7c252dc318322069c03>
        rdf:type          gpml:Point ;
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<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Shape/ffb2b>
        rdf:type             gpml:shape ;
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        gpml:align           "Center" ;
        gpml:centerX         "1374.7168359723262"^^xsd:double ;
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        gpml:fontWeight      "Normal" ;
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        gpml:textlabel       "" ;
        gpml:valign          "Middle" ;
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<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id29256dcf>
        rdf:type            gpml:Interaction ;
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        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "id29256dcf" ;
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        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id29256dcf/Point/b6db4e318069d5816ae9844b0d46f8fe> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id29256dcf/Point/7009047e4f3eb7f38bc05f42c398f156> ;
        gpml:lineStyle      "Solid" ;
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<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id5178da0d>
        rdf:type            gpml:Interaction ;
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        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "id5178da0d" ;
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        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
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<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Group/a29ba>
        rdf:type          gpml:Group ;
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        gpml:graphId      "a29ba" ;
        gpml:groupId      "f1cb3" ;
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<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Shape/fdf8d>
        rdf:type             gpml:shape ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Group/c7e3c> ;
        gpml:align           "Left" ;
        gpml:centerX         "1451.778096701023"^^xsd:double ;
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        gpml:valign          "Top" ;
        gpml:width           "202.44380659795388"^^xsd:double ;
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<http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/cee43>
        rdf:type             gpml:DataNode ;
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        gpml:align           "Center" ;
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        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
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        gpml:xrefId          "ENSG00000117020" ;
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<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/f403a>
        rdf:type            gpml:Interaction ;
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        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "f403a" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/f403a/Point/17758066e6c11d2792119e6f094bb9bc> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/f403a/Point/2909e53c5ea3132288d2229dd88555a1> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
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<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Comment/789cfec1f9e43a63b90bf5fd9dd2041c>
        rdf:type          gpml:Comment ;
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<http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/af357>
        rdf:type             gpml:DataNode ;
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        gpml:type            "GeneProduct" ;
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<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id7171d355/Point/a9ae11b97d40ed5e22759c23f4edcfab>
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<http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/b54dd>
        rdf:type             gpml:DataNode ;
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<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id9cf21b4e/Point/9f5d4584fc13d6e3c9cc92c403dd8cd2>
        rdf:type          gpml:Point ;
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<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Group/a605d>
        rdf:type                 gpml:Group ;
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<http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/f7569>
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<http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/c1f22>
        rdf:type             gpml:DataNode ;
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<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id29256dcf/Point/7009047e4f3eb7f38bc05f42c398f156>
        rdf:type          gpml:Point ;
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<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id1cf06f6b/Point/814d3b90b3c646a699b556684bca1f6f>
        rdf:type          gpml:Point ;
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<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Label/ed74a>
        rdf:type             gpml:Label ;
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        gpml:lineStyle       "Solid" ;
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        gpml:shapeType       "None" ;
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<http://rdf.wikipathways.org/Pathway/WP4674_r142545/State/e02c2>
        rdf:type            gpml:State ;
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        gpml:stateType      "Unknown" ;
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<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id5178da0d/Point/e3632abba3c3601356cd0eadf5dd4256>
        rdf:type          gpml:Point ;
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<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Comment/da059327423c96c07771b5397ada36a8>
        rdf:type          gpml:Comment ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id6245b6cd> ;
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<http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/af720>
        rdf:type             gpml:DataNode ;
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        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "af720" ;
        gpml:groupRef        "ac87c" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "PIK3R1" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "70.0"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000145675" ;
        gpml:zorder          "32827"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/cbf1c/Point/17250b8b3c952c1b323bec85837b0910>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/cbf1c> ;
        gpml:graphRef     "bb45e" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "756.7013422818796"^^xsd:double ;
        gpml:y            "202.53020134228194"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/GraphicalLine/a12ef/Point/54d5d7750e11aec4ef4e5392d4149422>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/GraphicalLine/a12ef> ;
        gpml:graphRef     "f6641" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "1078.3111194707603"^^xsd:double ;
        gpml:y            "458.53241194101855"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id9196c758/Point/9032752900f9db0f4a74383fa542374e>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id9196c758> ;
        gpml:graphRef     "b43d0" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "1112.2581240768075"^^xsd:double ;
        gpml:y            "198.38461538461502"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Comment/f87a7ee2cbd05f97193c7239a5e7f945>
        rdf:type          gpml:Comment ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545/State/d4d2e> ;
        gpml:commentText  "parentid=O15530; parentsymbol=PDK1; site=skQARANsFVGtAQy; position=ser241; sitegrpid=447693; ptm=p; direction=u" .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Label/c4b44>
        rdf:type             gpml:Label ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Group/c7e3c> ;
        gpml:align           "Center" ;
        gpml:centerX         "1469.6826994261341"^^xsd:double ;
        gpml:centerY         "89.30297993748535"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Bold" ;
        gpml:graphId         "c4b44" ;
        gpml:groupRef        "c7e3c" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:href            "" ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "None" ;
        gpml:textlabel       "Activating mutation" ;
        gpml:valign          "Middle" ;
        gpml:width           "144.06291834002673"^^xsd:double ;
        gpml:zorder          "33768"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id3fb4e606/Point/e582665bef98f5ddb6301df1bc5b900a>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id3fb4e606> ;
        gpml:graphRef     "b92bc" ;
        gpml:relX         "0.5"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "254.6572011129855"^^xsd:double ;
        gpml:y            "213.127"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id4d578d10/Point/7b11831d62d5e032b9ecb5cc1251805a>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id4d578d10> ;
        gpml:graphRef     "cf932" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "487.9668457046315"^^xsd:double ;
        gpml:y            "911.6088769028619"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/b770e>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Group/a605d> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:align           "Center" ;
        gpml:centerX         "348.19973170672074"^^xsd:double ;
        gpml:centerY         "67.18166472310354"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "b770e" ;
        gpml:groupRef        "e045b" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "FGFR3" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "70.0"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000068078" ;
        gpml:zorder          "33822"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/d1507>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Group/f9f69> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:align           "Center" ;
        gpml:centerX         "1000.1004273504259"^^xsd:double ;
        gpml:centerY         "70.5"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "d1507" ;
        gpml:groupRef        "e14c5" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "NOTCH2" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "70.0"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000134250" ;
        gpml:zorder          "32874"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/State/a0f1f>
        rdf:type            gpml:State ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:color          "0" ;
        gpml:fillColor      "ffffff" ;
        gpml:graphId        "a0f1f" ;
        gpml:graphRef       "f04f4" ;
        gpml:hasComment     <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Comment/88550acc9f7e98cf85110ea3630f4389> ;
        gpml:height         "15.0"^^xsd:double ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:relX           "-0.975"^^xsd:double ;
        gpml:relY           "1.0"^^xsd:double ;
        gpml:shapeType      "Oval" ;
        gpml:stateOf        <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/f04f4> ;
        gpml:stateType      "Unknown" ;
        gpml:textlabel      "P" ;
        gpml:width          "15.0"^^xsd:double ;
        gpml:zorder         "33802"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/a3aed>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:align           "Center" ;
        gpml:centerX         "537.657201112985"^^xsd:double ;
        gpml:centerY         "233.12679162072772"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "a3aed" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "PTEN" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "70.0"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000171862" ;
        gpml:zorder          "32821"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id4d578d10/Point/195d805478fb4c5a2396ceb99b4fd51c>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id4d578d10> ;
        gpml:graphRef     "b173b" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "487.9668457046315"^^xsd:double ;
        gpml:y            "941.8974964354733"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/State/e8abd>
        rdf:type            gpml:State ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:color          "0" ;
        gpml:fillColor      "ffffff" ;
        gpml:graphId        "e8abd" ;
        gpml:graphRef       "cee43" ;
        gpml:hasComment     <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Comment/2f0f7784c90e418e6f6ee76ee212080d> ;
        gpml:height         "15.0"^^xsd:double ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:relX           "0.9142857142857143"^^xsd:double ;
        gpml:relY           "0.9"^^xsd:double ;
        gpml:shapeType      "Oval" ;
        gpml:stateOf        <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/cee43> ;
        gpml:stateType      "Unknown" ;
        gpml:textlabel      "P" ;
        gpml:width          "15.0"^^xsd:double ;
        gpml:zorder         "32835"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/State/aa734>
        rdf:type            gpml:State ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:color          "0" ;
        gpml:fillColor      "ffffff" ;
        gpml:graphId        "aa734" ;
        gpml:graphRef       "b4b5d" ;
        gpml:height         "15.0"^^xsd:double ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:relX           "-0.9401778496358957"^^xsd:double ;
        gpml:relY           "-0.8469015795868654"^^xsd:double ;
        gpml:shapeType      "Hexagon" ;
        gpml:stateOf        <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/b4b5d> ;
        gpml:stateType      "Unknown" ;
        gpml:textlabel      "" ;
        gpml:width          "15.0"^^xsd:double ;
        gpml:zorder         "32769"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Group/c15a6>
        rdf:type          gpml:Group ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:groupId      "c15a6" ;
        gpml:style        "Group" .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id69d506bd/Point/a387153ecbb09e1e1be7cebb7e730bb5>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id69d506bd> ;
        gpml:graphRef     "d6359" ;
        gpml:relX         "0.5"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "651.5097447256651"^^xsd:double ;
        gpml:y            "850.1733231913108"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/idff58edfc/Point/e8a9dae9e93e9bfa9b877cc98f1c63a7>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/idff58edfc> ;
        gpml:graphRef     "cf704" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "756.7013422818796"^^xsd:double ;
        gpml:y            "131.5234899328859"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id7171d355/Point/f512247ccea238e9dde9cac0b131f28e>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id7171d355> ;
        gpml:graphRef     "cf932" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "452.9668457046315"^^xsd:double ;
        gpml:y            "901.6088769028619"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/GraphicalLine/e46c9/Point/39a1e35a22a158c7c87504f6e6f5b590>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/GraphicalLine/e46c9> ;
        gpml:graphRef     "f4221" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "1158.0668843620065"^^xsd:double ;
        gpml:y            "508.15081308220147"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/dcfec>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Group/f9f69> ;
        gpml:align           "Center" ;
        gpml:centerX         "1000.1004273504259"^^xsd:double ;
        gpml:centerY         "50.5"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "dcfec" ;
        gpml:groupRef        "e14c5" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "NOTCH1" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "70.0"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000148400" ;
        gpml:zorder          "32768"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Comment/6803b5e4d70e7c51a2f0884413cc9110>
        rdf:type          gpml:Comment ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545/State/dac9c> ;
        gpml:commentText  "parentid=P31751; parentsymbol=AKT2; site=sDGAtMKtFCGtPEy; position=thr309; sitegrpid=448537; ptm=p; direction=u" .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id88ef9d84/Point/a52ba3edd4b491bd12bd7663d00580ae>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id88ef9d84> ;
        gpml:graphRef     "f9f69" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "1000.1004273504259"^^xsd:double ;
        gpml:y            "88.5"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/d026f>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:align           "Center" ;
        gpml:centerX         "889.5469990783866"^^xsd:double ;
        gpml:centerY         "133.67399537931297"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "d026f" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "NUMB" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "70.0"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000133961" ;
        gpml:zorder          "32768"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Comment/b1e04841cf8863e2da357146d5004da6>
        rdf:type          gpml:Comment ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545/State/b7b88> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/State/ebab0> ;
        gpml:commentText  "parentid=P42345; parentsymbol=MTOR; site=tVPEsIHsFIGDGLV; position=ser2481; sitegrpid=447498; ptm=p; direction=u" .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id83f023a5>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:color          "0" ;
        gpml:connectorType  "Elbow" ;
        gpml:graphId        "id83f023a5" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id83f023a5/Point/2e5cd9a7156e1e6a79a03f17e9b7142d> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id83f023a5/Point/5f24139ac797977fa701c963bb38cd71> ;
        gpml:lineStyle      "Broken" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/State/c522c>
        rdf:type                 gpml:State ;
        dcterms:isPartOf         <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:biopaxRef           "fb2" ;
        gpml:color               "0" ;
        gpml:fillColor           "ffffff" ;
        gpml:graphId             "c522c" ;
        gpml:graphRef            "fbf7f" ;
        gpml:hasPublicationXref  <https://identifiers.org/pubmed/31695792> ;
        gpml:height              "15.0"^^xsd:double ;
        gpml:lineStyle           "Solid" ;
        gpml:lineThickness       "1.0"^^xsd:double ;
        gpml:relX                "-0.9660218948776571"^^xsd:double ;
        gpml:relY                "-1.0"^^xsd:double ;
        gpml:shapeType           "Hexagon" ;
        gpml:stateOf             <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/fbf7f> ;
        gpml:stateType           "Unknown" ;
        gpml:textlabel           "" ;
        gpml:width               "15.0"^^xsd:double ;
        gpml:zorder              "33825"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/GraphicalLine/ffa51/Point/ca50552a71f8464e339b89db101345d1>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/GraphicalLine/ffa51> ;
        gpml:graphRef     "d3354" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "300.80402674958805"^^xsd:double ;
        gpml:y            "1002.9303032398493"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/e8b0f>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:align           "Center" ;
        gpml:centerX         "668.6245638254368"^^xsd:double ;
        gpml:centerY         "141.5234899328859"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "e8b0f" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "FADD" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "70.0"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000168040" ;
        gpml:zorder          "32768"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/State/b4bb3>
        rdf:type            gpml:State ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:color          "0" ;
        gpml:fillColor      "ffffff" ;
        gpml:graphId        "b4bb3" ;
        gpml:graphRef       "f04f4" ;
        gpml:hasComment     <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Comment/172c2e38b749b2eb80e348135f5d34b4> ;
        gpml:height         "15.0"^^xsd:double ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:relX           "1.0"^^xsd:double ;
        gpml:relY           "1.0"^^xsd:double ;
        gpml:shapeType      "Oval" ;
        gpml:stateOf        <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/f04f4> ;
        gpml:stateType      "Unknown" ;
        gpml:textlabel      "P" ;
        gpml:width          "15.0"^^xsd:double ;
        gpml:zorder         "33802"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id9196c758/Point/eb616685ae4f57f716983ab20e47477d>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id9196c758> ;
        gpml:graphRef     "e2132" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "1113.7499999999998"^^xsd:double ;
        gpml:y            "80.5"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id2015c60/Point/e11c267db377cd6cc513ffb826b59890>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id2015c60> ;
        gpml:graphRef     "f595e" ;
        gpml:relX         "1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "327.0092970540771"^^xsd:double ;
        gpml:y            "416.04153159391217"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Comment/3d485485e980f91fe6fccd1d2cacc605>
        rdf:type          gpml:Comment ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545/State/a1e4d> ;
        gpml:commentText  "parentid=P27986; parentsymbol=PIK3R1; site=ENtEDQysLVEDDED; position=ser608; sitegrpid=448133; ptm=p; direction=u" .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id6245b6cd/Point/f2f2bb41b7931e514f432fde09f78ae4>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id6245b6cd> ;
        gpml:graphRef     "d0dfd" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "120.95239702885664"^^xsd:double ;
        gpml:y            "810.8817502340637"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/c0391>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Group/fe6d3> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:align           "Center" ;
        gpml:centerX         "764.9259637207432"^^xsd:double ;
        gpml:centerY         "542.6341241865046"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "c0391" ;
        gpml:groupRef        "a3124" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "MTOR" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "70.0"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000198793" ;
        gpml:zorder          "33810"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/b781d>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:align           "Center" ;
        gpml:centerX         "1001.2586290699271"^^xsd:double ;
        gpml:centerY         "826.7750697521741"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "b781d" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "TP63" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "70.0"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000073282" ;
        gpml:zorder          "32768"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Group/f9f69>
        rdf:type          gpml:Group ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:graphId      "f9f69" ;
        gpml:groupId      "e14c5" ;
        gpml:style        "Group" .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/idb1cc7053/Point/208539f2b1c4761ab8154d22d755a5d3>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/idb1cc7053> ;
        gpml:graphRef     "ddc68" ;
        gpml:relX         "1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "394.449227235615"^^xsd:double ;
        gpml:y            "1072.1891124743595"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/idb6f6ef82/Point/43eb1fe50c4830ea630ae8f0c8170084>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/idb6f6ef82> ;
        gpml:graphRef     "baa75" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "272.1572011129855"^^xsd:double ;
        gpml:y            "201.127"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/fc80d>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Group/a605d> ;
        gpml:align           "Center" ;
        gpml:centerX         "197.16228073752148"^^xsd:double ;
        gpml:centerY         "67.18166472310355"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "fc80d" ;
        gpml:groupRef        "e045b" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "EGFR" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "70.0"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000146648" ;
        gpml:zorder          "32768"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id624437ad>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "id624437ad" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id624437ad/Point/54aa78206794b3bcbcb7c8e052acf1b0> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id624437ad/Point/153b46cf919ab9f627c0e042cefb44dc> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Group/deb35>
        rdf:type          gpml:Group ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:graphId      "deb35" ;
        gpml:groupId      "e2a6a" ;
        gpml:style        "Group" .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/idb6f6ef82>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "idb6f6ef82" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/idb6f6ef82/Point/7c55d2922b1a9f2e6489b767aad604d6> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/idb6f6ef82/Point/43eb1fe50c4830ea630ae8f0c8170084> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/faa56/Point/f16ec6e669d2f26e669a77b3bff76f5f>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/faa56> ;
        gpml:graphRef     "c1f22" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "438.0656636373991"^^xsd:double ;
        gpml:y            "292.92103305477895"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id4e947078>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "id4e947078" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id4e947078/Point/b32473ce3a15e4b373abaf33051c2f17> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id4e947078/Point/918f861f1c3347d20427d9a2c0367ccc> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/GraphicalLine/a12ef/Point/1938e2573e25725719d34d66fe5e35b6>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/GraphicalLine/a12ef> ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "1116.624118794241"^^xsd:double ;
        gpml:y            "508.15081308220147"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/State/f8ff1>
        rdf:type                 gpml:State ;
        dcterms:isPartOf         <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:biopaxRef           "fb2" ;
        gpml:color               "0" ;
        gpml:fillColor           "ffffff" ;
        gpml:graphId             "f8ff1" ;
        gpml:graphRef            "cf704" ;
        gpml:hasPublicationXref  <https://identifiers.org/pubmed/31695792> ;
        gpml:height              "15.0"^^xsd:double ;
        gpml:lineStyle           "Solid" ;
        gpml:lineThickness       "1.0"^^xsd:double ;
        gpml:relX                "-0.9344667697063302"^^xsd:double ;
        gpml:relY                "-0.76"^^xsd:double ;
        gpml:shapeType           "Triangle" ;
        gpml:stateOf             <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/cf704> ;
        gpml:stateType           "Unknown" ;
        gpml:textlabel           "" ;
        gpml:width               "15.0"^^xsd:double ;
        gpml:zorder              "32769"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/b43d0>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:align           "Center" ;
        gpml:centerX         "1112.2581240768075"^^xsd:double ;
        gpml:centerY         "208.38461538461502"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "b43d0" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "CTNNB1" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "70.0"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000168036" ;
        gpml:zorder          "33812"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/State/ba440>
        rdf:type            gpml:State ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:color          "0" ;
        gpml:fillColor      "ffffff" ;
        gpml:graphId        "ba440" ;
        gpml:graphRef       "cf932" ;
        gpml:height         "15.0"^^xsd:double ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:relX           "-0.9660218948776571"^^xsd:double ;
        gpml:relY           "-1.0"^^xsd:double ;
        gpml:shapeType      "Hexagon" ;
        gpml:stateOf        <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/cf932> ;
        gpml:stateType      "Unknown" ;
        gpml:textlabel      "" ;
        gpml:width          "15.0"^^xsd:double ;
        gpml:zorder         "32769"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/idacd50709/Point/619414fc45473171e6c2f81aa0bfacd6>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/idacd50709> ;
        gpml:graphRef     "d6359" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "627.9337680621923"^^xsd:double ;
        gpml:y            "964.878048780487"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/e89aa>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Group/af5e4> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:align           "Center" ;
        gpml:centerX         "672.7372515125319"^^xsd:double ;
        gpml:centerY         "313.468"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "e89aa" ;
        gpml:groupRef        "cdbf1" ;
        gpml:hasComment      <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Comment/67a17100ae5fef126b5b8677720452b0> ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "REL" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "70.0"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000162924" ;
        gpml:zorder          "33830"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id6f89564e/Point/bf59eecfe5956b2eda2b525cb8a05617>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id6f89564e> ;
        gpml:graphRef     "a29ba" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "359.4722600170394"^^xsd:double ;
        gpml:y            "547.1642843154749"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id1cf06f6b/Point/fd1ddab184100345283847648f4cd9bf>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id1cf06f6b> ;
        gpml:graphRef     "f7569" ;
        gpml:relX         "0.5"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "1019.2156489621207"^^xsd:double ;
        gpml:y            "894.7984792624878"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/ida0b85c43/Point/c46e86389e58d18d7f63b74dd307f6a0>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/ida0b85c43> ;
        gpml:graphRef     "f8503" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "948.168803418803"^^xsd:double ;
        gpml:y            "775.4414081733131"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id793259d9>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:color          "0" ;
        gpml:connectorType  "Elbow" ;
        gpml:graphId        "id793259d9" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id793259d9/Point/8aede580e571abbe2daeffe3b52bc571> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id793259d9/Point/9f76dbf219d779ee6e963bc9dcea2d88> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/f29db/Point/1ceb0934044ed15d2448f2e2f8b5a625>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/f29db> ;
        gpml:graphRef     "c8d56" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "709.5"^^xsd:double ;
        gpml:y            "85.0"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/fd4dd>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:align           "Center" ;
        gpml:centerX         "1243.3103405817658"^^xsd:double ;
        gpml:centerY         "425.59891125782184"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "fd4dd" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "CSMD3" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "70.0"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000164796" ;
        gpml:zorder          "32880"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/idd374a88/Point/da00963f7ea35cff0b11f1bd53dbb137>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/idd374a88> ;
        gpml:graphRef     "e3b73" ;
        gpml:relX         "1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "127.91205795592617"^^xsd:double ;
        gpml:y            "416.04153159391217"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id69d506bd/Point/47892db9c36e660fc38bd4f9bdb1a266>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id69d506bd> ;
        gpml:graphRef     "ee3b2" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "718.1835249155636"^^xsd:double ;
        gpml:y            "818.9191056976218"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/idd2351f46/Point/b63eb8419fffb1fa34e821416f520dba>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/idd2351f46> ;
        gpml:graphRef     "c390f" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "264.08655714674995"^^xsd:double ;
        gpml:y            "788.099738825549"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Label/a26ea>
        rdf:type             gpml:Label ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:align           "Center" ;
        gpml:centerX         "1264.5347350704367"^^xsd:double ;
        gpml:centerY         "324.45864489468346"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Bold" ;
        gpml:graphId         "a26ea" ;
        gpml:height          "26.320069601612197"^^xsd:double ;
        gpml:href            "" ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "None" ;
        gpml:textlabel       "Oxidative damage" ;
        gpml:valign          "Middle" ;
        gpml:width           "91.17253948967164"^^xsd:double ;
        gpml:zorder          "33815"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Shape/a6900>
        rdf:type             gpml:shape ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:align           "Center" ;
        gpml:centerX         "688.5"^^xsd:double ;
        gpml:centerY         "601.0"^^xsd:double ;
        gpml:color           "c0c0c0" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "a6900" ;
        gpml:height          "1056.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "3.0"^^xsd:double ;
        gpml:shape           "0.0"^^xsd:double ;
        gpml:shapeType       "RoundedRectangle" ;
        gpml:textlabel       "" ;
        gpml:valign          "Middle" ;
        gpml:width           "1285.0"^^xsd:double ;
        gpml:zorder          "16384"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/idc4bc37ee>
        rdf:type                 gpml:Interaction ;
        dcterms:isPartOf         <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:biopaxRef           "fb2" ;
        gpml:color               "0" ;
        gpml:connectorType       "Straight" ;
        gpml:graphId             "idc4bc37ee" ;
        gpml:hasPoint            <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/idc4bc37ee/Point/9f1c3cdf618004363052a0914dd207d> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/idc4bc37ee/Point/3dc5b9917a09fe041b6899e1b07a3f8c> ;
        gpml:hasPublicationXref  <https://identifiers.org/pubmed/31695792> ;
        gpml:lineStyle           "Solid" ;
        gpml:lineThickness       "1.0"^^xsd:double ;
        gpml:zorder              "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id18d2fa71/Point/80791bcf21e28ae5e9a0f157c6c6bc21>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id18d2fa71> ;
        gpml:graphRef     "dea8b" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "781.8339400633806"^^xsd:double ;
        gpml:y            "872.0486340716812"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id6245b6cd/Point/ba25feaa2387d0f3494dfcae9eb6e61c>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id6245b6cd> ;
        gpml:graphRef     "f688a" ;
        gpml:relX         "-0.5"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "120.83843388588383"^^xsd:double ;
        gpml:y            "839.7230517595494"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/idb1cc7053/Point/7fad32e4f99aea430446836b505aa6f5>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/idb1cc7053> ;
        gpml:graphRef     "b781d" ;
        gpml:relX         "1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "1036.258629069927"^^xsd:double ;
        gpml:y            "826.7750697521741"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/State/cc1e0>
        rdf:type            gpml:State ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:color          "0" ;
        gpml:fillColor      "ffffff" ;
        gpml:graphId        "cc1e0" ;
        gpml:graphRef       "fc80d" ;
        gpml:height         "15.0"^^xsd:double ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:relX           "-0.8857142857142857"^^xsd:double ;
        gpml:relY           "-1.0"^^xsd:double ;
        gpml:shapeType      "Triangle" ;
        gpml:stateOf        <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/fc80d> ;
        gpml:stateType      "Unknown" ;
        gpml:textlabel      "" ;
        gpml:width          "15.0"^^xsd:double ;
        gpml:zorder         "32769"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/ad1b2>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Group/af5e4> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:align           "Center" ;
        gpml:centerX         "708.6633535004322"^^xsd:double ;
        gpml:centerY         "273.468"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "ad1b2" ;
        gpml:groupRef        "cdbf1" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "NFKB2" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "70.0"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000077150" ;
        gpml:zorder          "33832"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/b71e6>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "b71e6" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/b71e6/Point/4ed405f50ed83210e3dacee11fe897ac> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/b71e6/Point/bcdfbf15d7c5dd38e523aaddaf3cc71f> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "32805"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id18d2fa71/Point/398abce50fb957bd1fe8b67cfbe1de98>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id18d2fa71> ;
        gpml:graphRef     "c2e1e" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "752.8695516470303"^^xsd:double ;
        gpml:y            "872.7013561032961"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id17ef750/Point/ab61b2c4d5f19d24a26620989fa50b7>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id17ef750> ;
        gpml:graphRef     "bb45e" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "756.7013422818796"^^xsd:double ;
        gpml:y            "182.53020134228194"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id870ef7e2>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "id870ef7e2" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id870ef7e2/Point/5edc9308e651a83869d6b052b2255a0a> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id870ef7e2/Point/120b26b3a316b7e288c6f06858769414> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id83f023a5/Point/5f24139ac797977fa701c963bb38cd71>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id83f023a5> ;
        gpml:graphRef     "f688a" ;
        gpml:relX         "-0.5"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "120.83843388588383"^^xsd:double ;
        gpml:y            "859.7230517595494"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/State/ba1a5>
        rdf:type            gpml:State ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:color          "0" ;
        gpml:fillColor      "ffffff" ;
        gpml:graphId        "ba1a5" ;
        gpml:graphRef       "ee3b2" ;
        gpml:height         "15.0"^^xsd:double ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:relX           "-1.0"^^xsd:double ;
        gpml:relY           "-1.0"^^xsd:double ;
        gpml:shapeType      "Hexagon" ;
        gpml:stateOf        <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/ee3b2> ;
        gpml:stateType      "Unknown" ;
        gpml:textlabel      "" ;
        gpml:width          "15.0"^^xsd:double ;
        gpml:zorder         "33762"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id951ee543/Point/7328bd1e9f8709580077cc0bb175f88>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id951ee543> ;
        gpml:graphRef     "e8b0f" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "668.6245638254368"^^xsd:double ;
        gpml:y            "131.5234899328859"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/GraphicalLine/c337b/Point/3729570be6fe49eea38cd00eedc87bb6>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/GraphicalLine/c337b> ;
        gpml:graphRef     "fd4dd" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "1243.3103405817658"^^xsd:double ;
        gpml:y            "435.59891125782184"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/cb00c>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Group/c8d56> ;
        gpml:align           "Center" ;
        gpml:centerX         "746.0"^^xsd:double ;
        gpml:centerY         "67.0"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "cb00c" ;
        gpml:groupRef        "ea664" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "TNFR" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "70.0"^^xsd:double ;
        gpml:xrefDataSource  "Pfam" ;
        gpml:xrefId          "PF00020" ;
        gpml:zorder          "32768"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/State/c28c5>
        rdf:type            gpml:State ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:color          "0" ;
        gpml:fillColor      "ffffff" ;
        gpml:graphId        "c28c5" ;
        gpml:graphRef       "c0391" ;
        gpml:hasComment     <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Comment/cdf055ae6c883a3e07a76136388e8de1> ;
        gpml:height         "15.0"^^xsd:double ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:relX           "-1.0"^^xsd:double ;
        gpml:relY           "0.8"^^xsd:double ;
        gpml:shapeType      "Oval" ;
        gpml:stateOf        <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/c0391> ;
        gpml:stateType      "Unknown" ;
        gpml:textlabel      "P" ;
        gpml:width          "15.0"^^xsd:double ;
        gpml:zorder         "33811"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/c94ca/Point/3c76226d8f5c65216944b93aafd7b741>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/c94ca> ;
        gpml:graphRef     "c1f22" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "438.0656636373991"^^xsd:double ;
        gpml:y            "272.92103305477895"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/idef07ed1d/Point/8f3edb2532090844199fa0bf509e6ca7>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/idef07ed1d> ;
        gpml:graphRef     "d6359" ;
        gpml:relX         "1.0"^^xsd:double ;
        gpml:relY         "0.5"^^xsd:double ;
        gpml:x            "675.0857213891379"^^xsd:double ;
        gpml:y            "936.201867383193"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/idd761eea6/Point/93ba45eaeed1d6db8415c651d771dd51>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/idd761eea6> ;
        gpml:graphRef     "dd419" ;
        gpml:relX         "1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "555.0656636373991"^^xsd:double ;
        gpml:y            "347.9870589354298"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/de75e>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Group/f595e> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:align           "Center" ;
        gpml:centerX         "280.0092970540771"^^xsd:double ;
        gpml:centerY         "416.04153159391217"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "de75e" ;
        gpml:groupRef        "f3b7c" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "PRKAA2" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "70.0"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000162409" ;
        gpml:zorder          "32856"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id4d578d10>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "id4d578d10" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id4d578d10/Point/7b11831d62d5e032b9ecb5cc1251805a> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id4d578d10/Point/195d805478fb4c5a2396ceb99b4fd51c> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Group/d6359>
        rdf:type          gpml:Group ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:graphId      "d6359" ;
        gpml:groupId      "c7c51" ;
        gpml:style        "Complex" .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/d853e/Point/1c60a4ac54813e0b822f45d2b5ecb70b>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/d853e> ;
        gpml:graphRef     "baa75" ;
        gpml:relX         "1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "354.1572011129855"^^xsd:double ;
        gpml:y            "233.627"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/State/d5362>
        rdf:type            gpml:State ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:color          "0" ;
        gpml:fillColor      "ffffff" ;
        gpml:graphId        "d5362" ;
        gpml:graphRef       "a7c20" ;
        gpml:height         "15.0"^^xsd:double ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:relX           "-1.0"^^xsd:double ;
        gpml:relY           "-0.7"^^xsd:double ;
        gpml:shapeType      "Hexagon" ;
        gpml:stateOf        <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/a7c20> ;
        gpml:stateType      "Unknown" ;
        gpml:textlabel      "" ;
        gpml:width          "15.0"^^xsd:double ;
        gpml:zorder         "32769"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/dcfe8>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Group/d6359> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:align           "Center" ;
        gpml:centerX         "628.0857213891379"^^xsd:double ;
        gpml:centerY         "872.1733231913109"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "dcfe8" ;
        gpml:groupRef        "c7c51" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "CDKN1A" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "70.0"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000124762" ;
        gpml:zorder          "32768"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/State/d4d2e>
        rdf:type                 gpml:State ;
        dcterms:isPartOf         <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:biopaxRef           "f47" ;
        gpml:color               "0" ;
        gpml:fillColor           "ffffff" ;
        gpml:graphId             "d4d2e" ;
        gpml:graphRef            "c1f22" ;
        gpml:hasComment          <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Comment/f87a7ee2cbd05f97193c7239a5e7f945> ;
        gpml:hasPublicationXref  <https://identifiers.org/pubmed/10455013> ;
        gpml:height              "15.0"^^xsd:double ;
        gpml:lineStyle           "Solid" ;
        gpml:lineThickness       "1.0"^^xsd:double ;
        gpml:relX                "1.0"^^xsd:double ;
        gpml:relY                "1.0"^^xsd:double ;
        gpml:shapeType           "Oval" ;
        gpml:stateOf             <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/c1f22> ;
        gpml:stateType           "Unknown" ;
        gpml:textlabel           "P" ;
        gpml:width               "15.0"^^xsd:double ;
        gpml:zorder              "33804"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/State/fbbf4>
        rdf:type            gpml:State ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:color          "0" ;
        gpml:fillColor      "ffffff" ;
        gpml:graphId        "fbbf4" ;
        gpml:graphRef       "b0ab3" ;
        gpml:height         "15.0"^^xsd:double ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:relX           "-1.0"^^xsd:double ;
        gpml:relY           "-0.9"^^xsd:double ;
        gpml:shapeType      "Triangle" ;
        gpml:stateOf        <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/b0ab3> ;
        gpml:stateType      "Unknown" ;
        gpml:textlabel      "" ;
        gpml:width          "15.0"^^xsd:double ;
        gpml:zorder         "32823"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Comment/a9dd498245a62c89cfc748e79106961d>
        rdf:type          gpml:Comment ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545/State/ccaa9> ;
        gpml:commentText  "parentid=Q13541; parentsymbol=EIF4EBP1; site=PPGDysttPGGtLFs; position=thr37; sitegrpid=447497; ptm=p; direction=d" .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Comment/172c2e38b749b2eb80e348135f5d34b4>
        rdf:type          gpml:Comment ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545/State/b4bb3> ;
        gpml:commentText  "parentid=Q13541; parentsymbol=EIF4EBP1; site=rNsPVtktPPRDLPt; position=thr70; sitegrpid=447528; ptm=p; direction=d" .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/idc4bc37ee/Point/9f1c3cdf618004363052a0914dd207d>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/idc4bc37ee> ;
        gpml:graphRef     "b43d0" ;
        gpml:relX         "1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "1147.2581240768075"^^xsd:double ;
        gpml:y            "208.38461538461502"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id5fe91b3e/Point/d48832eea947bb479e6158ed415db27b>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id5fe91b3e> ;
        gpml:graphRef     "af5e4" ;
        gpml:relX         "1.0"^^xsd:double ;
        gpml:relY         "0.5"^^xsd:double ;
        gpml:x            "799.4567847882456"^^xsd:double ;
        gpml:y            "309.46811322385486"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/f29db>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:color          "0" ;
        gpml:connectorType  "Elbow" ;
        gpml:graphId        "f29db" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/f29db/Point/1ceb0934044ed15d2448f2e2f8b5a625> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/f29db/Point/99649d0460d560e49d26cf1c8914d978> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "33838"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id2db3d091/Point/c8bac20697a75afd636f353874987899>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id2db3d091> ;
        gpml:graphRef     "dcfe8" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "628.0857213891379"^^xsd:double ;
        gpml:y            "882.1733231913109"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id624437ad/Point/54aa78206794b3bcbcb7c8e052acf1b0>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id624437ad> ;
        gpml:graphRef     "b9623" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "245.97565631518916"^^xsd:double ;
        gpml:y            "369.9870589354298"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/State/dac9c>
        rdf:type            gpml:State ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:color          "0" ;
        gpml:fillColor      "ffffff" ;
        gpml:graphId        "dac9c" ;
        gpml:graphRef       "f924d" ;
        gpml:hasComment     <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Comment/6803b5e4d70e7c51a2f0884413cc9110> ;
        gpml:height         "15.0"^^xsd:double ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:relX           "0.7714285714285715"^^xsd:double ;
        gpml:relY           "1.0"^^xsd:double ;
        gpml:shapeType      "Oval" ;
        gpml:stateOf        <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/f924d> ;
        gpml:stateType      "Unknown" ;
        gpml:textlabel      "P" ;
        gpml:width          "15.0"^^xsd:double ;
        gpml:zorder         "-1"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/State/a0dbe>
        rdf:type            gpml:State ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:color          "0" ;
        gpml:fillColor      "ffffff" ;
        gpml:graphId        "a0dbe" ;
        gpml:graphRef       "f688a" ;
        gpml:height         "15.0"^^xsd:double ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:relX           "-1.0"^^xsd:double ;
        gpml:relY           "1.0"^^xsd:double ;
        gpml:shapeType      "Hexagon" ;
        gpml:stateOf        <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/f688a> ;
        gpml:stateType      "Unknown" ;
        gpml:textlabel      "" ;
        gpml:width          "15.0"^^xsd:double ;
        gpml:zorder         "32769"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id3c9c3b9f/Point/eeb1e2e4a33f742f4528a8868b2718d4>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id3c9c3b9f> ;
        gpml:graphRef     "a605d" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "271.9181297756612"^^xsd:double ;
        gpml:y            "85.18166472310355"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Group/c390f>
        rdf:type          gpml:Group ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:graphId      "c390f" ;
        gpml:groupId      "f9985" ;
        gpml:style        "None" .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/GraphicalLine/a12ef>
        rdf:type            gpml:GraphicalLine ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "a12ef" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP4674_r142545/GraphicalLine/a12ef/Point/54d5d7750e11aec4ef4e5392d4149422> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/GraphicalLine/a12ef/Point/1938e2573e25725719d34d66fe5e35b6> ;
        gpml:lineStyle      "Broken" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "32884"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Group/c7e3c>
        rdf:type          gpml:Group ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:groupId      "c7e3c" ;
        gpml:style        "Group" .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Group/dd419>
        rdf:type          gpml:Group ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:graphId      "dd419" ;
        gpml:groupId      "b1ebf" ;
        gpml:style        "Group" ;
        gpml:textlabel    "AKT" .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/e1afd>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:align           "Center" ;
        gpml:centerX         "535.0473647131384"^^xsd:double ;
        gpml:centerY         "639.0120485861415"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "e1afd" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "RPS6KB2" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "80.0"^^xsd:double ;
        gpml:xrefDataSource  "Entrez Gene" ;
        gpml:xrefId          "6199" ;
        gpml:zorder          "33799"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id6f89564e/Point/ac156fcf6d52b7a479347e1aefcd5581>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id6f89564e> ;
        gpml:graphRef     "c390f" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "307.08655714675007"^^xsd:double ;
        gpml:y            "745.3127017885118"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/ideff6c101/Point/15f45605daae18403b3a0172b7721d85>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/ideff6c101> ;
        gpml:graphRef     "f04f4" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "438.9538770550739"^^xsd:double ;
        gpml:y            "629.0120485861415"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/ida8acd52d/Point/4ec30aedcaf8fc15c11c39a9bcec6007>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/ida8acd52d> ;
        gpml:graphRef     "af5e4" ;
        gpml:relX         "-0.5"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "669.1671348314603"^^xsd:double ;
        gpml:y            "231.46845289541923"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Group/f6641>
        rdf:type          gpml:Group ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:graphId      "f6641" ;
        gpml:groupId      "b44cf" ;
        gpml:style        "Group" .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/pub/f64>
        rdf:type          gpml:PublicationXref ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id6245b6cd> ;
        gpml:id           "" .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id907c03df/Point/5ec1b9e00c629230fd4baa06ee60134>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id907c03df> ;
        gpml:graphRef     "baa75" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "272.1572011129855"^^xsd:double ;
        gpml:y            "266.127"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id7a37cac1>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "id7a37cac1" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id7a37cac1/Point/d8d80f5acbf11e6a8ea6d2dbf4a4ee2c> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id7a37cac1/Point/b42d27560b00d4e16d80821ccda2e6d2> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/State/c595d>
        rdf:type            gpml:State ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:color          "0" ;
        gpml:fillColor      "ffffff" ;
        gpml:graphId        "c595d" ;
        gpml:graphRef       "f04f4" ;
        gpml:hasComment     <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Comment/ce83605bac3f42ab9d91267d3d9e4b1b> ;
        gpml:height         "15.0"^^xsd:double ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:relX           "-0.951384095635234"^^xsd:double ;
        gpml:relY           "-0.9056261343012738"^^xsd:double ;
        gpml:shapeType      "Oval" ;
        gpml:stateOf        <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/f04f4> ;
        gpml:stateType      "Unknown" ;
        gpml:textlabel      "P" ;
        gpml:width          "15.0"^^xsd:double ;
        gpml:zorder         "33802"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/efff3>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:align           "Center" ;
        gpml:centerX         "1265.3205128205157"^^xsd:double ;
        gpml:centerY         "208.38461538461502"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "efff3" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "NFE2L2" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "70.0"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000116044" ;
        gpml:zorder          "33814"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/State/a8c22>
        rdf:type                 gpml:State ;
        dcterms:isPartOf         <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:biopaxRef           "d41" ;
        gpml:color               "0" ;
        gpml:fillColor           "ffffff" ;
        gpml:graphId             "a8c22" ;
        gpml:graphRef            "f4aa5" ;
        gpml:hasComment          <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Comment/789cfec1f9e43a63b90bf5fd9dd2041c> ;
        gpml:hasPublicationXref  <https://identifiers.org/pubmed/12150915> ;
        gpml:height              "15.0"^^xsd:double ;
        gpml:lineStyle           "Solid" ;
        gpml:lineThickness       "1.0"^^xsd:double ;
        gpml:relX                "1.0"^^xsd:double ;
        gpml:relY                "-1.0"^^xsd:double ;
        gpml:shapeType           "Oval" ;
        gpml:stateOf             <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/f4aa5> ;
        gpml:stateType           "Unknown" ;
        gpml:textlabel           "P" ;
        gpml:width               "15.0"^^xsd:double ;
        gpml:zorder              "32855"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/State/d74f2>
        rdf:type                 gpml:State ;
        dcterms:isPartOf         <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:biopaxRef           "fb2" ;
        gpml:color               "0" ;
        gpml:fillColor           "ffffff" ;
        gpml:graphId             "d74f2" ;
        gpml:graphRef            "efff3" ;
        gpml:hasPublicationXref  <https://identifiers.org/pubmed/31695792> ;
        gpml:height              "15.0"^^xsd:double ;
        gpml:lineStyle           "Solid" ;
        gpml:lineThickness       "1.0"^^xsd:double ;
        gpml:relX                "-0.9276985027564921"^^xsd:double ;
        gpml:relY                "-0.9441069258809103"^^xsd:double ;
        gpml:shapeType           "Triangle" ;
        gpml:stateOf             <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/efff3> ;
        gpml:stateType           "Unknown" ;
        gpml:textlabel           "" ;
        gpml:width               "15.0"^^xsd:double ;
        gpml:zorder              "33815"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id4e947078/Point/b32473ce3a15e4b373abaf33051c2f17>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id4e947078> ;
        gpml:graphRef     "d848a" ;
        gpml:relX         "1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "175.05770308299589"^^xsd:double ;
        gpml:y            "312.5407047387609"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/e2a5f/Point/b1552b5c0cacf0dc36ddf328e0c0c2c3>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/e2a5f> ;
        gpml:graphRef     "d2be7" ;
        gpml:relX         "1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "473.0656636373991"^^xsd:double ;
        gpml:y            "233.12679162072772"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/State/c2672>
        rdf:type                 gpml:State ;
        dcterms:isPartOf         <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:biopaxRef           "fb2" ;
        gpml:color               "0" ;
        gpml:fillColor           "ffffff" ;
        gpml:graphId             "c2672" ;
        gpml:graphRef            "a8698" ;
        gpml:hasPublicationXref  <https://identifiers.org/pubmed/31695792> ;
        gpml:height              "15.0"^^xsd:double ;
        gpml:lineStyle           "Solid" ;
        gpml:lineThickness       "1.0"^^xsd:double ;
        gpml:relX                "-1.0"^^xsd:double ;
        gpml:relY                "-0.7"^^xsd:double ;
        gpml:shapeType           "Hexagon" ;
        gpml:stateOf             <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/a8698> ;
        gpml:stateType           "Unknown" ;
        gpml:textlabel           "" ;
        gpml:width               "15.0"^^xsd:double ;
        gpml:zorder              "32769"^^xsd:long .

<https://identifiers.org/pubmed/10455013>
        rdf:type          gpml:PublicationXref ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545/State/d4d2e> ;
        gpml:database     "Pubmed" ;
        gpml:id           "10455013" .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/b23bb>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:align           "Center" ;
        gpml:centerX         "627.7818147352465"^^xsd:double ;
        gpml:centerY         "1003.3441734417357"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "b23bb" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "RB1" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "70.0"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000139687" ;
        gpml:zorder          "32768"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Label/ddc68>
        rdf:type             gpml:Label ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:align           "Center" ;
        gpml:centerX         "349.449227235615"^^xsd:double ;
        gpml:centerY         "1072.1891124743595"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Bold" ;
        gpml:graphId         "ddc68" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:href            "" ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "None" ;
        gpml:textlabel       "Differentiation" ;
        gpml:valign          "Middle" ;
        gpml:width           "90.0"^^xsd:double ;
        gpml:zorder          "32872"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/faa56/Point/2dca465a47fb23b864ac72e66129db43>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/faa56> ;
        gpml:graphRef     "dd419" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "438.0656636373991"^^xsd:double ;
        gpml:y            "329.9870589354298"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/de84f>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Group/e2561> ;
        gpml:align           "Center" ;
        gpml:centerX         "1265.320512820516"^^xsd:double ;
        gpml:centerY         "146.26495726495716"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "de84f" ;
        gpml:groupRef        "bb289" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "CUL3" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "70.0"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000036257" ;
        gpml:zorder          "33813"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/b9623>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:align           "Center" ;
        gpml:centerX         "245.97565631518916"^^xsd:double ;
        gpml:centerY         "359.9870589354298"^^xsd:double ;
        gpml:color           "ff" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "b9623" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "Metformin" ;
        gpml:type            "Metabolite" ;
        gpml:valign          "Middle" ;
        gpml:width           "70.0"^^xsd:double ;
        gpml:xrefDataSource  "Wikidata" ;
        gpml:xrefId          "Q19484" ;
        gpml:zorder          "32768"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Comment/f93df8028f56404c9f1ccb500f1090fe>
        rdf:type          gpml:Comment ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/66233253> ;
        gpml:commentText  "RelA" ;
        gpml:source       "OCR" .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/idaf4c7f80>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "idaf4c7f80" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/idaf4c7f80/Point/b71880e08b46959fa7d93bd6c22a41dc> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/idaf4c7f80/Point/a31c3a606d3a31c8c07c4457a3948cb1> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/c79f6>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Group/a29ba> ;
        gpml:align           "Center" ;
        gpml:centerX         "469.77777777777794"^^xsd:double ;
        gpml:centerY         "536.6944444444453"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "c79f6" ;
        gpml:groupRef        "f1cb3" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "MLST8" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "70.0"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000167965" ;
        gpml:zorder          "32768"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/d0dfd>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:align           "Center" ;
        gpml:centerX         "120.95239702885664"^^xsd:double ;
        gpml:centerY         "800.8817502340637"^^xsd:double ;
        gpml:color           "ff6600" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "d0dfd" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "HPV E6" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "60.0"^^xsd:double ;
        gpml:xrefDataSource  "" ;
        gpml:xrefId          "" ;
        gpml:zorder          "32768"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id624437ad/Point/153b46cf919ab9f627c0e042cefb44dc>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id624437ad> ;
        gpml:graphRef     "f595e" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "245.00929705407708"^^xsd:double ;
        gpml:y            "394.04153159391217"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/State/c275b>
        rdf:type            gpml:State ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:color          "0" ;
        gpml:fillColor      "ffffff" ;
        gpml:graphId        "c275b" ;
        gpml:graphRef       "ef180" ;
        gpml:height         "15.0"^^xsd:double ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:relX           "-0.9428571428571428"^^xsd:double ;
        gpml:relY           "-1.0"^^xsd:double ;
        gpml:shapeType      "Triangle" ;
        gpml:stateOf        <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/ef180> ;
        gpml:stateType      "Unknown" ;
        gpml:textlabel      "" ;
        gpml:width          "15.0"^^xsd:double ;
        gpml:zorder         "33822"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/ee3b2>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:align           "Center" ;
        gpml:centerX         "753.1835249155636"^^xsd:double ;
        gpml:centerY         "818.9191056976218"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "ee3b2" ;
        gpml:height          "36.22056314756787"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "p16 INK4a\n(CDKN2A)" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "70.0"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000147889" ;
        gpml:zorder          "33761"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/idaf4c7f80/Point/b71880e08b46959fa7d93bd6c22a41dc>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/idaf4c7f80> ;
        gpml:graphRef     "fe6d3" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "684.9661190008749"^^xsd:double ;
        gpml:y            "521.1331870024586"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/GraphicalLine/f49d4/Point/38d03f8d640090ac518e5b9bd78a7831>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/GraphicalLine/f49d4> ;
        gpml:graphRef     "af5e4" ;
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<http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/e3b73>
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<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Shape/cbe82>
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<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id7a37cac1/Point/b42d27560b00d4e16d80821ccda2e6d2>
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<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id5fe91b3e/Point/23550e233687febef3401dbb49304b7d>
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<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id19ff6cd6/Point/a4350e27909f448c9c4d7ac14ce64985>
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<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id62611738/Point/ebf9ad7d6116a6a33d8fdfd3e7e36035>
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<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id960f1d40/Point/87821fc2bd403598cbfc22aedbf20429>
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<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/idd2351f46/Point/b7d647cb0653648e878572c4629797a0>
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<http://rdf.wikipathways.org/Pathway/WP4674_r142545/State/c807a>
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<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Group/f595e>
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<http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/d8cd9>
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<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Label/a3747>
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<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/idff58edfc>
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<http://rdf.wikipathways.org/Pathway/WP4674_r142545>
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<http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/fc7b8> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/a3aed> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/a7c20> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/ee18e> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/e1afd> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/b23bb> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/f8503> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/a1e2b> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/c79f6> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/c3a2d> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/b781d> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/baa16> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/dcfec> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/e6270> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/cee2e> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/d8cd9> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/fd4dd> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/de75e> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/f567f> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/d2be7> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/cf704> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/d8776> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/b770e> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/ef180> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/efff3> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/ad1b2> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/e1aa5> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/f2627> , 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        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "fc56d" ;
        gpml:groupRef        "f9985" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "SESN2" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "70.0"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000130766" ;
        gpml:zorder          "32868"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/baa16>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Group/bd8fc> ;
        gpml:align           "Center" ;
        gpml:centerX         "272.1130950434298"^^xsd:double ;
        gpml:centerY         "139.5234899328859"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "baa16" ;
        gpml:groupRef        "b61ea" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "NRAS" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "70.0"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000213281" ;
        gpml:zorder          "32846"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/f46ee>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Group/a29ba> ;
        gpml:align           "Center" ;
        gpml:centerX         "443.9259637207432"^^xsd:double ;
        gpml:centerY         "557.6341241865046"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "f46ee" ;
        gpml:groupRef        "f1cb3" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "MTOR" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "70.0"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000198793" ;
        gpml:zorder          "32859"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id5ef1a8e>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "id5ef1a8e" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id5ef1a8e/Point/3d7ba9a912ae2f5630210ce51e069e04> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id5ef1a8e/Point/516873610703e3182bf645ec4b68a39e> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/a7c20>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Group/f6641> ;
        gpml:align           "Center" ;
        gpml:centerX         "1078.3111194707603"^^xsd:double ;
        gpml:centerY         "440.53241194101855"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "a7c20" ;
        gpml:groupRef        "b44cf" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "SMAD4" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "70.0"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000141646" ;
        gpml:zorder          "32768"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/GraphicalLine/e46c9>
        rdf:type            gpml:GraphicalLine ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "e46c9" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP4674_r142545/GraphicalLine/e46c9/Point/39a1e35a22a158c7c87504f6e6f5b590> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/GraphicalLine/e46c9/Point/685b0be786de0f8b92430e687db6d510> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id17ef750>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "id17ef750" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id17ef750/Point/ab61b2c4d5f19d24a26620989fa50b7> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id17ef750/Point/45d31ed9a88a424a27c9ff702d35a73a> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/State/fda26>
        rdf:type                 gpml:State ;
        dcterms:isPartOf         <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:biopaxRef           "fb2" ;
        gpml:color               "0" ;
        gpml:fillColor           "ffffff" ;
        gpml:graphId             "fda26" ;
        gpml:graphRef            "f0d17" ;
        gpml:hasPublicationXref  <https://identifiers.org/pubmed/31695792> ;
        gpml:height              "15.0"^^xsd:double ;
        gpml:lineStyle           "Solid" ;
        gpml:lineThickness       "1.0"^^xsd:double ;
        gpml:relX                "-0.9200559608274186"^^xsd:double ;
        gpml:relY                "-0.8469015795868836"^^xsd:double ;
        gpml:shapeType           "Triangle" ;
        gpml:stateOf             <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/f0d17> ;
        gpml:stateType           "Unknown" ;
        gpml:textlabel           "" ;
        gpml:width               "15.0"^^xsd:double ;
        gpml:zorder              "32769"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/d853e>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "d853e" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/d853e/Point/a392acd52d41bc4d0916d9c5cd96bf13> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/d853e/Point/1c60a4ac54813e0b822f45d2b5ecb70b> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "32818"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/ideff6c101>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "ideff6c101" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/ideff6c101/Point/15f45605daae18403b3a0172b7721d85> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/ideff6c101/Point/ad0a8dd1d07be4355687716a26e7b50b> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/b71e6/Point/4ed405f50ed83210e3dacee11fe897ac>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/b71e6> ;
        gpml:graphRef     "dd419" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "438.0656636373991"^^xsd:double ;
        gpml:y            "365.9870589354298"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/d8ba7>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:align           "Center" ;
        gpml:centerX         "1158.392107235526"^^xsd:double ;
        gpml:centerY         "434.6097389275188"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "d8ba7" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "VEGFA" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "70.0"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000112715" ;
        gpml:zorder          "32882"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/e0738>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Group/d6359> ;
        gpml:align           "Center" ;
        gpml:centerX         "627.7818147352465"^^xsd:double ;
        gpml:centerY         "942.878048780487"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "e0738" ;
        gpml:groupRef        "c7c51" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "CDK6" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "70.0"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000105810" ;
        gpml:zorder          "32877"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/idd374a88>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "idd374a88" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/idd374a88/Point/e3ddace8e51c543ec99017404c485ac3> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/idd374a88/Point/da00963f7ea35cff0b11f1bd53dbb137> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/State/bae58>
        rdf:type            gpml:State ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:color          "0" ;
        gpml:fillColor      "ffffff" ;
        gpml:graphId        "bae58" ;
        gpml:graphRef       "ee18e" ;
        gpml:height         "15.0"^^xsd:double ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:relX           "-0.9999999999999962"^^xsd:double ;
        gpml:relY           "-0.92"^^xsd:double ;
        gpml:shapeType      "Hexagon" ;
        gpml:stateOf        <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/ee18e> ;
        gpml:stateType      "Unknown" ;
        gpml:textlabel      "" ;
        gpml:width          "15.0"^^xsd:double ;
        gpml:zorder         "33758"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id870ef7e2/Point/5edc9308e651a83869d6b052b2255a0a>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id870ef7e2> ;
        gpml:graphRef     "b43d0" ;
        gpml:relX         "0.5"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "1129.7581240768075"^^xsd:double ;
        gpml:y            "198.38461538461502"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/a8698>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Group/e2561> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:align           "Center" ;
        gpml:centerX         "1265.320512820516"^^xsd:double ;
        gpml:centerY         "122.26495726495716"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "a8698" ;
        gpml:groupRef        "bb289" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "KEAP1" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "70.0"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000079999" ;
        gpml:zorder          "32768"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/b1a41>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Group/a605d> ;
        gpml:align           "Center" ;
        gpml:centerX         "119.77776916992161"^^xsd:double ;
        gpml:centerY         "67.18166472310354"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "b1a41" ;
        gpml:groupRef        "e045b" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "ERBB2" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "70.0"^^xsd:double ;
        gpml:xrefDataSource  "Entrez Gene" ;
        gpml:xrefId          "2064" ;
        gpml:zorder          "33818"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id3fb4e606/Point/6e8bd5a05e3ecbbc5ecaedcc4169eec7>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id3fb4e606> ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "597.0"^^xsd:double ;
        gpml:y            "234.23411322385482"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/b4b5d>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:align           "Center" ;
        gpml:centerX         "628.5583232077776"^^xsd:double ;
        gpml:centerY         "808.4224382341012"^^xsd:double ;
        gpml:color           "cc0099" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "b4b5d" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "MIRLET7C" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "82.66707168894285"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000199030" ;
        gpml:zorder          "32768"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/bc0b1>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Group/baa75> ;
        gpml:align           "Center" ;
        gpml:centerX         "307.1572011129855"^^xsd:double ;
        gpml:centerY         "244.127"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "bc0b1" ;
        gpml:groupRef        "ac87c" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "PIK3R2" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "70.0"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000105647" ;
        gpml:zorder          "32829"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Group/baa75>
        rdf:type          gpml:Group ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:graphId      "baa75" ;
        gpml:groupId      "ac87c" ;
        gpml:style        "Complex" ;
        gpml:textlabel    "PI3K class 1a" .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/f924d>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Group/dd419> ;
        gpml:align           "Center" ;
        gpml:centerX         "438.0656636373991"^^xsd:double ;
        gpml:centerY         "347.9870589354298"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "f924d" ;
        gpml:groupRef        "b1ebf" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "AKT2" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "70.0"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000105221" ;
        gpml:zorder          "-2"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/e1de9>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Group/bd8fc> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:align           "Center" ;
        gpml:centerX         "342.1130950434298"^^xsd:double ;
        gpml:centerY         "139.5234899328859"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "e1de9" ;
        gpml:groupRef        "b61ea" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "KRAS" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "70.0"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000133703" ;
        gpml:zorder          "32847"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id4ff3e838/Point/5297978759bbe30b2b9df7a0030a0524>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id4ff3e838> ;
        gpml:graphRef     "f04f4" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "438.9538770550739"^^xsd:double ;
        gpml:y            "649.0120485861415"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id29256dcf/Point/b6db4e318069d5816ae9844b0d46f8fe>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id29256dcf> ;
        gpml:graphRef     "cee2e" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "752.3985917442304"^^xsd:double ;
        gpml:y            "926.2093093511317"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/pub/c69>
        rdf:type          gpml:PublicationXref ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id85e33a01> ;
        gpml:id           "" .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id4ff3e838>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "id4ff3e838" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id4ff3e838/Point/5ceef0c2a21c2121de8aebd5da5dc62c> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id4ff3e838/Point/5297978759bbe30b2b9df7a0030a0524> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/State/ebcc0>
        rdf:type                 gpml:State ;
        dcterms:isPartOf         <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:biopaxRef           "fb2" ;
        gpml:color               "0" ;
        gpml:fillColor           "ffffff" ;
        gpml:graphId             "ebcc0" ;
        gpml:graphRef            "e0738" ;
        gpml:hasPublicationXref  <https://identifiers.org/pubmed/31695792> ;
        gpml:height              "15.0"^^xsd:double ;
        gpml:lineStyle           "Solid" ;
        gpml:lineThickness       "1.0"^^xsd:double ;
        gpml:relX                "-1.0"^^xsd:double ;
        gpml:relY                "-0.5"^^xsd:double ;
        gpml:shapeType           "Triangle" ;
        gpml:stateOf             <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/e0738> ;
        gpml:stateType           "Unknown" ;
        gpml:textlabel           "" ;
        gpml:width               "15.0"^^xsd:double ;
        gpml:zorder              "32878"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/a3f85>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Group/c390f> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:align           "Center" ;
        gpml:centerX         "307.08655714674995"^^xsd:double ;
        gpml:centerY         "763.3127017885118"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "a3f85" ;
        gpml:groupRef        "f9985" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "DDIT4" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "70.0"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000168209" ;
        gpml:zorder          "32768"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/a809a>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:align           "Center" ;
        gpml:centerX         "681.6541790741156"^^xsd:double ;
        gpml:centerY         "756.0202778957055"^^xsd:double ;
        gpml:color           "14961e" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Bold" ;
        gpml:graphId         "a809a" ;
        gpml:height          "27.94653705953826"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "RoundedRectangle" ;
        gpml:textlabel       "Cell cycle" ;
        gpml:type            "Pathway" ;
        gpml:valign          "Middle" ;
        gpml:width           "91.17253948967164"^^xsd:double ;
        gpml:xrefDataSource  "WikiPathways" ;
        gpml:xrefId          "WP179" ;
        gpml:zorder          "28672"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/f2627>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Group/fe6d3> ;
        gpml:align           "Center" ;
        gpml:centerX         "766.1096375193937"^^xsd:double ;
        gpml:centerY         "499.6322498184127"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "f2627" ;
        gpml:groupRef        "a3124" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "MAPKAP1" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "70.0"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000119487" ;
        gpml:zorder          "32768"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id1cf06f6b>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "id1cf06f6b" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id1cf06f6b/Point/fd1ddab184100345283847648f4cd9bf> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id1cf06f6b/Point/814d3b90b3c646a699b556684bca1f6f> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Label/d3354>
        rdf:type             gpml:Label ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:align           "Center" ;
        gpml:centerX         "345.80402674958805"^^xsd:double ;
        gpml:centerY         "1002.9303032398493"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Bold" ;
        gpml:graphId         "d3354" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:href            "" ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "None" ;
        gpml:textlabel       "Proliferation" ;
        gpml:valign          "Middle" ;
        gpml:width           "90.0"^^xsd:double ;
        gpml:zorder          "28672"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id88ef9d84>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "id88ef9d84" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id88ef9d84/Point/d0a8cc16a4e0228ad8482e4828bc2ad0> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id88ef9d84/Point/a52ba3edd4b491bd12bd7663d00580ae> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id2015c60>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "id2015c60" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id2015c60/Point/6b1dd93a21aa65c009871bf4f848afce> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id2015c60/Point/e11c267db377cd6cc513ffb826b59890> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/66233253>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Group/af5e4> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:align           "Center" ;
        gpml:centerX         "672.7372515125319"^^xsd:double ;
        gpml:centerY         "293.468"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "" ;
        gpml:groupRef        "cdbf1" ;
        gpml:hasComment      <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Comment/f93df8028f56404c9f1ccb500f1090fe> ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "RELA" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "70.0"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000173039" ;
        gpml:zorder          "33828"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/GraphicalLine/ffa51/Point/808f18b7f049cccb20e51f7781217431>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/GraphicalLine/ffa51> ;
        gpml:graphRef     "f688a" ;
        gpml:relX         "-0.5"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "120.83843388588383"^^xsd:double ;
        gpml:y            "859.7230517595494"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/idd761eea6>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:color          "0" ;
        gpml:connectorType  "Elbow" ;
        gpml:graphId        "idd761eea6" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/idd761eea6/Point/93ba45eaeed1d6db8415c651d771dd51> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/idd761eea6/Point/deb057d0dc85d9cffe90b73be3a645ff> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id17ef750/Point/45d31ed9a88a424a27c9ff702d35a73a>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id17ef750> ;
        gpml:graphRef     "cf704" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "756.7013422818796"^^xsd:double ;
        gpml:y            "151.5234899328859"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/e2132>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:align           "Center" ;
        gpml:centerX         "1113.7499999999998"^^xsd:double ;
        gpml:centerY         "70.5"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "e2132" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "FAT1" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "70.0"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000083857" ;
        gpml:zorder          "32768"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/a1e2b>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        gpml:align           "Center" ;
        gpml:centerX         "438.0656636373991"^^xsd:double ;
        gpml:centerY         "477.4119019642824"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "a1e2b" ;
        gpml:height          "20.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "RHEB" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "70.0"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000106615" ;
        gpml:zorder          "32858"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id3cd48500/Point/ee8ca04ab66111fe203738b9c4b40a08>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id3cd48500> ;
        gpml:graphRef     "f9f69" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.5"^^xsd:double ;
        gpml:x            "957.1004273504259"^^xsd:double ;
        gpml:y            "74.5"^^xsd:double .
