@prefix biopax:  <http://www.biopax.org/release/biopax-level3.owl#> .
@prefix cito:    <http://purl.org/spar/cito/> .
@prefix dc:      <http://purl.org/dc/elements/1.1/> .
@prefix dcterms: <http://purl.org/dc/terms/> .
@prefix foaf:    <http://xmlns.com/foaf/0.1/> .
@prefix freq:    <http://purl.org/cld/freq/> .
@prefix gpml:    <http://vocabularies.wikipathways.org/gpml#> .
@prefix obo:     <http://purl.obolibrary.org/obo/> .
@prefix owl:     <http://www.w3.org/2002/07/owl#> .
@prefix pav:     <http://purl.org/pav/> .
@prefix prov:    <http://www.w3.org/ns/prov#> .
@prefix rdf:     <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix rdfs:    <http://www.w3.org/2000/01/rdf-schema#> .
@prefix skos:    <http://www.w3.org/2004/02/skos/core#> .
@prefix void:    <http://rdfs.org/ns/void#> .
@prefix wp:      <http://vocabularies.wikipathways.org/wp#> .
@prefix wprdf:   <http://rdf.wikipathways.org/> .
@prefix xsd:     <http://www.w3.org/2001/XMLSchema#> .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/e5223>
        rdf:type                 gpml:Interaction ;
        dcterms:isPartOf         <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:biopaxRef           "d01" ;
        gpml:color               "0" ;
        gpml:connectorType       "Elbow" ;
        gpml:graphId             "e5223" ;
        gpml:hasPoint            <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/e5223/Point/ab61b2c4d5f19d24a26620989fa50b7> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/e5223/Point/c2ff291bce5bdb3f863c93ef8ffe9144> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/e5223/Point/80791bcf21e28ae5e9a0f157c6c6bc21> ;
        gpml:hasPublicationXref  <https://identifiers.org/pubmed/17660942> ;
        gpml:lineStyle           "Solid" ;
        gpml:lineThickness       "1.0"^^xsd:double ;
        gpml:zorder              "33089"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/iddfb5e58b/Point/dffaf95d6d30f8732a052d2c0e548d25>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/iddfb5e58b> ;
        gpml:graphRef     "d0d0b" ;
        gpml:relX         "1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "1016.132582582951"^^xsd:double ;
        gpml:y            "456.8916621814047"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/DataNode/e12e0>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:align           "Center" ;
        gpml:centerX         "801.0738325829489"^^xsd:double ;
        gpml:centerY         "239.9951593432695"^^xsd:double ;
        gpml:color           "cc3300" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "e12e0" ;
        gpml:height          "28.5"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "Nestor-Guillermo \nprogeria syndrome" ;
        gpml:type            "Unknown" ;
        gpml:valign          "Middle" ;
        gpml:width           "107.8824999999963"^^xsd:double ;
        gpml:xrefDataSource  "Wikidata" ;
        gpml:xrefId          "Q55784059" ;
        gpml:zorder          "32768"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/id61369ff8>
        rdf:type                 gpml:Interaction ;
        dcterms:isPartOf         <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:biopaxRef           "ec8" ;
        gpml:color               "0" ;
        gpml:connectorType       "Elbow" ;
        gpml:graphId             "id61369ff8" ;
        gpml:hasPoint            <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/id61369ff8/Point/e152776e0b695612e17e4d3970394af8> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/id61369ff8/Point/fbab06ea23cdb90ef8417f3650f4f041> ;
        gpml:hasPublicationXref  <https://identifiers.org/pubmed/32153505> ;
        gpml:lineStyle           "Solid" ;
        gpml:lineThickness       "1.0"^^xsd:double ;
        gpml:zorder              "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/a1db9/Point/d5f76d66e7b3d33af8e305b841f558c8>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/a1db9> ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "757.9669314673597"^^xsd:double ;
        gpml:y            "413.64605543710024"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Label/f20f8>
        rdf:type             gpml:Label ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:align           "Center" ;
        gpml:centerX         "325.1352282361001"^^xsd:double ;
        gpml:centerY         "114.31942692162714"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "f20f8" ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:href            "" ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "None" ;
        gpml:textlabel       "Stimulation" ;
        gpml:valign          "Middle" ;
        gpml:width           "90.0"^^xsd:double ;
        gpml:zorder          "28672"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/eca08/Point/e582665bef98f5ddb6301df1bc5b900a>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/eca08> ;
        gpml:graphRef     "e228e" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "280.13522823610015"^^xsd:double ;
        gpml:y            "241.48824787082964"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/b5342/Point/3d7ba9a912ae2f5630210ce51e069e04>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/b5342> ;
        gpml:graphRef     "a84d6" ;
        gpml:relX         "1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "1054.8240136268855"^^xsd:double ;
        gpml:y            "622.6772189135808"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/id750caaa3/Point/68f55b6083ca0326392b872b1405af94>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/id750caaa3> ;
        gpml:graphRef     "ac0c0" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "588.2626198963845"^^xsd:double ;
        gpml:y            "467.0021506999701"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/id42186e6>
        rdf:type            gpml:GraphicalLine ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:color          "0" ;
        gpml:connectorType  "Elbow" ;
        gpml:graphId        "id42186e6" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/id42186e6/Point/c36eb8716848fc441a93dd82b326bdc1> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/id42186e6/Point/4b1eb853cb63ac2f8dcb5cd4cbae7a73> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/id2c06b01e/Point/2ff6cb254f4d58bfa646637b27304bf2>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/id2c06b01e> ;
        gpml:graphRef     "df33d" ;
        gpml:relX         "1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "915.2545825829528"^^xsd:double ;
        gpml:y            "576.8216088443393"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170>
        rdfs:seeAlso           <https://www.wikipathways.org/instance/WP5103_r119170> ;
        gpml:author            "[UlasBabayigit, Eweitz, Fehrhart, MaintBot]" ;
        gpml:boardHeight       "1114.4649814676675"^^xsd:double ;
        gpml:boardWidth        "1493.9391194802722"^^xsd:double ;
        gpml:data-Source       "WikiPathways" ;
        gpml:hasDataNode       <http://rdf.wikipathways.org/Pathway/WP5103_r119170/DataNode/d9f15> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/DataNode/c5a96> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/DataNode/e12e0> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/DataNode/e6172> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/DataNode/d0ebe> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/DataNode/a3ce7> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/DataNode/b72f3> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/DataNode/e8a6f> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/DataNode/fab90> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/DataNode/e440d> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/DataNode/fc6f0> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/DataNode/d0d0b> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/DataNode/ce6fc> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/DataNode/a7d5e> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/DataNode/ebb99> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/DataNode/d6538> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/DataNode/ec7b0> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/DataNode/a51ed> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/DataNode/d2328> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/DataNode/f6307> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/DataNode/bd4e6> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/DataNode/eb3f8> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/DataNode/ec575> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/DataNode/b5858> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/DataNode/c7166> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/DataNode/c5353> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/DataNode/efb22> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/DataNode/f50aa> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/DataNode/c6fc0> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/DataNode/e7757> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/DataNode/e0bcb> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/DataNode/a1689> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/DataNode/e2665> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/DataNode/c9144> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/DataNode/a83ee> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/DataNode/e7926> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/DataNode/fc0e0> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/DataNode/e8061> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/DataNode/aec98> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/DataNode/aaaed> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/DataNode/f0234> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/DataNode/b8ed0> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/DataNode/d1975> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/DataNode/ff0fb> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/DataNode/d7ddc> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/DataNode/f4495> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/DataNode/bf030> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/DataNode/f626b> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/DataNode/df33d> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/DataNode/a84d6> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/DataNode/db1fb> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/DataNode/fdf9f> ;
        gpml:hasGraphicalLine  <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/cb43d> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/c363f> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/ba127> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/e87cd> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/ide614247e> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/a3f39> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/cb3ec> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/b2689> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/e3c84> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/ecbee> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/b5342> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/de018> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/e88d6> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/a14a3> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/e654c> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/a507b> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/dd30c> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/eca08> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/a1db9> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/e2019> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/id42186e6> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/b8dbb> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/ad194> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/bf07c> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/dea16> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/idc66823a3> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/bf102> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/id17b91f80> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/d812e> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/iddaec0a84> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/f5767> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/a8443> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/e6b93> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/idaef5ff69> ;
        gpml:hasGroup          <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Group/b2571> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Group/e2c06> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Group/a762f> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Group/b27ab> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Group/e2f4a> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Group/d7512> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Group/f219c> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Group/aa473> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Group/b0da8> ;
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<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/id44122d0>
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<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/id364035b0/Point/a60d92c93621e173b488516560d5e8eb>
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<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/e6447>
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<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/id364035b0/Point/393822f214e75c940a2a7e283a764efa>
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<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/abc5a/Point/c7154b6dffc0f2ea2c7d142691a09d90>
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<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Label/bd0be>
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<http://rdf.wikipathways.org/Pathway/WP5103_r119170/DataNode/b72f3>
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<http://rdf.wikipathways.org/Pathway/WP5103_r119170/State/bacda>
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<http://rdf.wikipathways.org/Pathway/WP5103_r119170/DataNode/a83ee>
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<http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/a507b>
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<https://identifiers.org/pubmed/29381406>
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<http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/e87cd/Point/5edc9308e651a83869d6b052b2255a0a>
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<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/e5223/Point/c2ff291bce5bdb3f863c93ef8ffe9144>
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<http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/a1db9/Point/a387153ecbb09e1e1be7cebb7e730bb5>
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<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Label/f3f7f>
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<http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/a14a3/Point/1f1151f052861fad436de5eac858b903>
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<http://rdf.wikipathways.org/Pathway/WP5103_r119170/DataNode/c5353>
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<http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/b2689>
        rdf:type                 gpml:GraphicalLine ;
        dcterms:isPartOf         <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:biopaxRef           "b52" ;
        gpml:color               "0" ;
        gpml:connectorType       "Straight" ;
        gpml:graphId             "b2689" ;
        gpml:hasPoint            <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/b2689/Point/7009047e4f3eb7f38bc05f42c398f156> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/b2689/Point/b6db4e318069d5816ae9844b0d46f8fe> ;
        gpml:hasPublicationXref  <https://identifiers.org/pubmed/31796734> ;
        gpml:lineStyle           "Solid" ;
        gpml:lineThickness       "1.0"^^xsd:double ;
        gpml:zorder              "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/ide614247e/Point/25311b0161f70c572597424120ec6a8b>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/ide614247e> ;
        gpml:graphRef     "e8fb3" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "840.1330544445436"^^xsd:double ;
        gpml:y            "181.0285874649378"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/DataNode/e2665>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:align           "Center" ;
        gpml:centerX         "363.62816970558765"^^xsd:double ;
        gpml:centerY         "815.508908317835"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "e2665" ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "ZMPSTE24" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "90.0"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000084073" ;
        gpml:zorder          "33083"^^xsd:long .

<https://identifiers.org/pubmed/17660942>
        rdf:type          gpml:PublicationXref ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/e5223> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/e5979> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/a5ff1> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/abc5a> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/addfd> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/b3ecb> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/c4c53> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/ae707> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/e6447> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/a7c8e> ;
        gpml:database     "Pubmed" ;
        gpml:id           "17660942" .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/cb43d>
        rdf:type                 gpml:GraphicalLine ;
        dcterms:isPartOf         <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:biopaxRef           "d72" ;
        gpml:color               "ff0000" ;
        gpml:connectorType       "Elbow" ;
        gpml:graphId             "cb43d" ;
        gpml:hasPoint            <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/cb43d/Point/b42d27560b00d4e16d80821ccda2e6d2> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/cb43d/Point/9f76dbf219d779ee6e963bc9dcea2d88> ;
        gpml:hasPublicationXref  <https://identifiers.org/pubmed/29989768> ;
        gpml:lineStyle           "Solid" ;
        gpml:lineThickness       "1.0"^^xsd:double ;
        gpml:zorder              "33052"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/DataNode/ce6fc>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:align           "Center" ;
        gpml:centerX         "1009.8240136268856"^^xsd:double ;
        gpml:centerY         "532.726077556159"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "ce6fc" ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "Asprosin" ;
        gpml:type            "Protein" ;
        gpml:valign          "Middle" ;
        gpml:width           "90.0"^^xsd:double ;
        gpml:xrefDataSource  "UniProtKB" ;
        gpml:xrefId          "P35555" ;
        gpml:zorder          "32812"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/a3f39/Point/fd1ddab184100345283847648f4cd9bf>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/a3f39> ;
        gpml:graphRef     "b27ab" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "677.8600303517707"^^xsd:double ;
        gpml:y            "777.8228139365931"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/a5ff1>
        rdf:type                 gpml:Interaction ;
        dcterms:isPartOf         <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:biopaxRef           "d01" ;
        gpml:color               "0" ;
        gpml:connectorType       "Straight" ;
        gpml:graphId             "a5ff1" ;
        gpml:hasPoint            <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/a5ff1/Point/c9c2796182d59e58bae2d64a34df5188> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/a5ff1/Point/aa96088af772e47dd775523e4a46249b> ;
        gpml:hasPublicationXref  <https://identifiers.org/pubmed/17660942> ;
        gpml:lineStyle           "Solid" ;
        gpml:lineThickness       "1.0"^^xsd:double ;
        gpml:zorder              "33048"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/ida340ce1/Point/fce0343460a8f27d9aa7232526b25d2e>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/ida340ce1> ;
        gpml:graphRef     "e7757" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "734.8600303517707"^^xsd:double ;
        gpml:y            "589.6992040844311"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/ae707>
        rdf:type                 gpml:Interaction ;
        dcterms:isPartOf         <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:biopaxRef           "d01" ;
        gpml:color               "0" ;
        gpml:connectorType       "Straight" ;
        gpml:graphId             "ae707" ;
        gpml:hasPoint            <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/ae707/Point/a1ad7ebbf25b42c2f87ed84cc9c8b137> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/ae707/Point/ac1ce30a3eae07dc2c991d3c7de4cda7> ;
        gpml:hasPublicationXref  <https://identifiers.org/pubmed/17660942> ;
        gpml:lineStyle           "Solid" ;
        gpml:lineThickness       "1.0"^^xsd:double ;
        gpml:zorder              "33057"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Label/d746d>
        rdf:type             gpml:Label ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:align           "Center" ;
        gpml:centerX         "1193.1731217620563"^^xsd:double ;
        gpml:centerY         "944.2825166193877"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "d746d" ;
        gpml:height          "69.51735074626865"^^xsd:double ;
        gpml:href            "" ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "None" ;
        gpml:textlabel       "Growth arrest\nApoptosis\nCell migration\netc." ;
        gpml:valign          "Middle" ;
        gpml:width           "90.0"^^xsd:double ;
        gpml:zorder          "28672"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Shape/c1ad4>
        rdf:type             gpml:shape ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:align           "Center" ;
        gpml:centerX         "64.0649535080641"^^xsd:double ;
        gpml:centerY         "135.12937312327233"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "c1ad4" ;
        gpml:height          "30.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shape           "0.0"^^xsd:double ;
        gpml:shapeType       "Oval" ;
        gpml:textlabel       "" ;
        gpml:valign          "Middle" ;
        gpml:width           "30.0"^^xsd:double ;
        gpml:zorder          "33097"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Label/cf329>
        rdf:type             gpml:Label ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:align           "Center" ;
        gpml:centerX         "149.037069183776"^^xsd:double ;
        gpml:centerY         "136.27859345737033"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "cf329" ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:href            "" ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "None" ;
        gpml:textlabel       "Methylatioin" ;
        gpml:valign          "Middle" ;
        gpml:width           "69.84164579875119"^^xsd:double ;
        gpml:zorder          "33098"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/e88d6>
        rdf:type                 gpml:GraphicalLine ;
        dcterms:isPartOf         <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:biopaxRef           "fb5" ;
        gpml:color               "0" ;
        gpml:connectorType       "Straight" ;
        gpml:graphId             "e88d6" ;
        gpml:hasPoint            <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/e88d6/Point/f512247ccea238e9dde9cac0b131f28e> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/e88d6/Point/8aede580e571abbe2daeffe3b52bc571> ;
        gpml:hasPublicationXref  <https://identifiers.org/pubmed/12921235> ;
        gpml:lineStyle           "Solid" ;
        gpml:lineThickness       "1.0"^^xsd:double ;
        gpml:zorder              "33040"^^xsd:long .

<https://identifiers.org/pubmed/25620207>
        rdf:type          gpml:PublicationXref ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/ide242ce3a> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/id2b53a9ce> ;
        gpml:database     "Pubmed" ;
        gpml:id           "25620207" .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/e654c>
        rdf:type            gpml:GraphicalLine ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "e654c" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/e654c/Point/ee8ca04ab66111fe203738b9c4b40a08> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/e654c/Point/9eeb107c9a984ebf5114e9b6a5da3b1e> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/id1eace11e/Point/ddd54ef53264bf3c6e316d8841b75e68>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/id1eace11e> ;
        gpml:graphRef     "e8fb3" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "840.1330544445436"^^xsd:double ;
        gpml:y            "181.0285874649378"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/id61369ff8/Point/fbab06ea23cdb90ef8417f3650f4f041>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/id61369ff8> ;
        gpml:graphRef     "df33d" ;
        gpml:relX         "1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "915.2545825829528"^^xsd:double ;
        gpml:y            "576.8216088443393"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/dea16/Point/44e5a453ba78ffd23d4d18aff785f5f7>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/dea16> ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "885.1348325829499"^^xsd:double ;
        gpml:y            "478.32267235252317"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/ecbee/Point/56c8258e9f4762ec1dd4b25bf1eb9185>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/ecbee> ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "1223.3857075829471"^^xsd:double ;
        gpml:y            "368.8699360341152"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/id44122d0/Point/5679a96f2bb692a149b4fd94fb787360>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/id44122d0> ;
        gpml:graphRef     "a3ce7" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "1009.8240136268855"^^xsd:double ;
        gpml:y            "710.9505343432669"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/b3ecb/Anchor/b6c5f>
        rdf:type          gpml:Anchor ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/b3ecb> ;
        gpml:graphId      "b6c5f" ;
        gpml:position     "0.4"^^xsd:double ;
        gpml:shape        "None" .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/id750caaa3>
        rdf:type                 gpml:Interaction ;
        dcterms:isPartOf         <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:biopaxRef           "f72" ;
        gpml:color               "0" ;
        gpml:connectorType       "Straight" ;
        gpml:graphId             "id750caaa3" ;
        gpml:hasComment          <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Comment/d871bc837eb13424720e53a67e761ab7> ;
        gpml:hasPoint            <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/id750caaa3/Point/68f55b6083ca0326392b872b1405af94> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/id750caaa3/Point/1797fdd1848738bed129019640e6ae74> ;
        gpml:hasPublicationXref  <https://identifiers.org/pubmed/7796919> ;
        gpml:lineStyle           "Solid" ;
        gpml:lineThickness       "1.0"^^xsd:double ;
        gpml:zorder              "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/DataNode/a1689>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:align           "Center" ;
        gpml:centerX         "1256.432582582953"^^xsd:double ;
        gpml:centerY         "456.8916621814047"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "a1689" ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "POLD1" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "90.0"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000062822" ;
        gpml:zorder          "32813"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/DataNode/a3ce7>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:align           "Center" ;
        gpml:centerX         "1009.8240136268856"^^xsd:double ;
        gpml:centerY         "698.4505343432669"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "a3ce7" ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "TGFB1" ;
        gpml:type            "Protein" ;
        gpml:valign          "Middle" ;
        gpml:width           "90.0"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000105329" ;
        gpml:zorder          "32768"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/cb3ec/Point/120b26b3a316b7e288c6f06858769414>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/cb3ec> ;
        gpml:graphRef     "ffc08" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "380.9039781012599"^^xsd:double ;
        gpml:y            "320.76799567713556"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/e6447/Point/ca18f2d1a545f5c18bf17fbd4c012009>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/e6447> ;
        gpml:graphRef     "fab90" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "318.62816970558754"^^xsd:double ;
        gpml:y            "595.2904956771363"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/d812e/Point/230f48bd3bc54434fdd6ade86b9587a2>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/d812e> ;
        gpml:graphRef     "ea7c9" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "280.1352282361001"^^xsd:double ;
        gpml:y            "142.49077020520951"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/ad194/Point/8ca3ff53bd86da17111fc88ef0ec3507>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/ad194> ;
        gpml:graphRef     "ce6fc" ;
        gpml:relX         "1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "1054.8240136268855"^^xsd:double ;
        gpml:y            "532.726077556159"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Label/da3a4>
        rdf:type             gpml:Label ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:align           "Center" ;
        gpml:centerX         "144.24704433513"^^xsd:double ;
        gpml:centerY         "167.4587866434987"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "da3a4" ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:href            "" ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "None" ;
        gpml:textlabel       "Metabolite" ;
        gpml:valign          "Middle" ;
        gpml:width           "60.82881144380738"^^xsd:double ;
        gpml:zorder          "28672"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/a507b/Point/23550e233687febef3401dbb49304b7d>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/a507b> ;
        gpml:graphRef     "d0d0b" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "971.132582582951"^^xsd:double ;
        gpml:y            "444.3916621814047"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/DataNode/f4495>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:align           "Center" ;
        gpml:centerX         "475.01508258294723"^^xsd:double ;
        gpml:centerY         "239.9951593432695"^^xsd:double ;
        gpml:color           "cc3300" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "f4495" ;
        gpml:height          "28.5"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "Mandibuloacral\ndysplasia" ;
        gpml:type            "Unknown" ;
        gpml:valign          "Middle" ;
        gpml:width           "90.0"^^xsd:double ;
        gpml:xrefDataSource  "Wikidata" ;
        gpml:xrefId          "Q16968886" ;
        gpml:zorder          "32768"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/iddfb5e58b/Point/f596ddbca609bd72774029fbf718a5d>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/iddfb5e58b> ;
        gpml:graphRef     "e8a6f" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "1064.5009115867033"^^xsd:double ;
        gpml:y            "456.8916621814047"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/e3c84>
        rdf:type                 gpml:GraphicalLine ;
        dcterms:isPartOf         <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:biopaxRef           "c59" ;
        gpml:color               "0" ;
        gpml:connectorType       "Straight" ;
        gpml:graphId             "e3c84" ;
        gpml:hasPoint            <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/e3c84/Point/b620cf0922c5c7c252dc318322069c03> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/e3c84/Point/337d092ad2f6d7d22089aaa2c12f3249> ;
        gpml:hasPublicationXref  <https://identifiers.org/pubmed/26993153> ;
        gpml:lineStyle           "Solid" ;
        gpml:lineThickness       "1.0"^^xsd:double ;
        gpml:zorder              "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/DataNode/e440d>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:align           "Center" ;
        gpml:centerX         "692.573832582949"^^xsd:double ;
        gpml:centerY         "239.9951593432695"^^xsd:double ;
        gpml:color           "cc3300" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "e440d" ;
        gpml:height          "28.5"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "Keppen-Lubinsky\nsyndrome" ;
        gpml:type            "Unknown" ;
        gpml:valign          "Middle" ;
        gpml:width           "109.11750000000347"^^xsd:double ;
        gpml:xrefDataSource  "Wikidata" ;
        gpml:xrefId          "Q3961676" ;
        gpml:zorder          "32768"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/e6b93/Point/153b46cf919ab9f627c0e042cefb44dc>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/e6b93> ;
        gpml:graphRef     "a1689" ;
        gpml:relX         "1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "1301.432582582953"^^xsd:double ;
        gpml:y            "456.8916621814047"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/id61369ff8/Point/e152776e0b695612e17e4d3970394af8>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/id61369ff8> ;
        gpml:graphRef     "ce6fc" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "964.8240136268855"^^xsd:double ;
        gpml:y            "532.726077556159"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/ecbee>
        rdf:type                 gpml:GraphicalLine ;
        dcterms:isPartOf         <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:biopaxRef           "d72" , "fcf" ;
        gpml:color               "ff0000" ;
        gpml:connectorType       "Elbow" ;
        gpml:graphId             "ecbee" ;
        gpml:hasPoint            <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/ecbee/Point/56c8258e9f4762ec1dd4b25bf1eb9185> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/ecbee/Point/b931b1f07f47c508ff4dacff8b02b0d3> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/ecbee/Point/54aa78206794b3bcbcb7c8e052acf1b0> ;
        gpml:hasPublicationXref  <https://identifiers.org/pubmed/29989768> , <https://identifiers.org/pubmed/28476236> ;
        gpml:lineStyle           "Solid" ;
        gpml:lineThickness       "1.0"^^xsd:double ;
        gpml:zorder              "32780"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Label/fdeb1>
        rdf:type             gpml:Label ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:align           "Center" ;
        gpml:centerX         "49.64337257180535"^^xsd:double ;
        gpml:centerY         "77.30855622575037"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "fdeb1" ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:href            "" ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "None" ;
        gpml:textlabel       "Legend" ;
        gpml:valign          "Middle" ;
        gpml:width           "50.05263157894808"^^xsd:double ;
        gpml:zorder          "33103"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/InfoBox/2f95c5af280a3d9fd1be4d3a6ccad71b>
        rdf:type          gpml:InfoBox ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:centerX      "0.0"^^xsd:double ;
        gpml:centerY      "0.0"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/DataNode/c6fc0>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Group/b27ab> ;
        gpml:align           "Center" ;
        gpml:centerX         "734.8600303517707"^^xsd:double ;
        gpml:centerY         "790.3228139365931"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "c6fc0" ;
        gpml:groupRef        "b27ab" ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "PARP1" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "90.0"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000143799" ;
        gpml:zorder          "33096"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/ida223d25e>
        rdf:type                 gpml:Interaction ;
        dcterms:isPartOf         <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:biopaxRef           "b08" , "c20" ;
        gpml:color               "0" ;
        gpml:connectorType       "Straight" ;
        gpml:graphId             "ida223d25e" ;
        gpml:hasPoint            <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/ida223d25e/Point/43039df2212c681e38f9824d33b2de66> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/ida223d25e/Point/90add8addc6a74b02c177171977fb09f> ;
        gpml:hasPublicationXref  <https://identifiers.org/pubmed/29381406> , <https://identifiers.org/pubmed/32439107> ;
        gpml:lineStyle           "Solid" ;
        gpml:lineThickness       "1.0"^^xsd:double ;
        gpml:zorder              "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/DataNode/db1fb>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Group/b27ab> ;
        gpml:align           "Center" ;
        gpml:centerX         "734.8600303517707"^^xsd:double ;
        gpml:centerY         "765.322813936593"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "db1fb" ;
        gpml:groupRef        "b27ab" ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "BANF1" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "90.0"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000175334" ;
        gpml:zorder          "33095"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/f5767/Point/e3632abba3c3601356cd0eadf5dd4256>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/f5767> ;
        gpml:graphRef     "ffc08" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "458.01137633331115"^^xsd:double ;
        gpml:y            "308.26799567713556"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/ide242ce3a>
        rdf:type                 gpml:Interaction ;
        dcterms:isPartOf         <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:biopaxRef           "d50" ;
        gpml:color               "0" ;
        gpml:connectorType       "Straight" ;
        gpml:graphId             "ide242ce3a" ;
        gpml:hasPoint            <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/ide242ce3a/Point/35832b00dbcac11cf6435c6bf20d79d5> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/ide242ce3a/Point/bfe91c862409a7b72b81fa17c23450cb> ;
        gpml:hasPublicationXref  <https://identifiers.org/pubmed/25620207> ;
        gpml:lineStyle           "Solid" ;
        gpml:lineThickness       "1.0"^^xsd:double ;
        gpml:zorder              "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/idab17cda9/Point/7fa56b6715d26a66efc5044d86a3d659>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/idab17cda9> ;
        gpml:graphRef     "a1689" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "1211.432582582953"^^xsd:double ;
        gpml:y            "456.8916621814047"^^xsd:double .

<https://identifiers.org/pubmed/27871366>
        rdf:type          gpml:PublicationXref ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/iddfb5e58b> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/idab17cda9> ;
        gpml:database     "Pubmed" ;
        gpml:id           "27871366" .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/DataNode/efb22>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:align           "Center" ;
        gpml:centerX         "1190.3388325829412"^^xsd:double ;
        gpml:centerY         "239.9951593432695"^^xsd:double ;
        gpml:color           "cc3300" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "efb22" ;
        gpml:height          "28.5"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "MDP \nsyndrome" ;
        gpml:type            "Unknown" ;
        gpml:valign          "Middle" ;
        gpml:width           "70.88249999999607"^^xsd:double ;
        gpml:xrefDataSource  "Wikidata" ;
        gpml:xrefId          "Q17120696" ;
        gpml:zorder          "32768"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/eca08>
        rdf:type            gpml:GraphicalLine ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "eca08" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/eca08/Point/4b012fe529871b137b78b4e829fefa60> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/eca08/Point/e582665bef98f5ddb6301df1bc5b900a> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/a99e0/Point/814d3b90b3c646a699b556684bca1f6f>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/a99e0> ;
        gpml:graphRef     "e8fb3" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "840.1330544445436"^^xsd:double ;
        gpml:y            "181.0285874649378"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/id17b91f80/Point/ad01556e22fd8d730757efe9c1139ee6>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/id17b91f80> ;
        gpml:graphRef     "efb22" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "1190.3388325829412"^^xsd:double ;
        gpml:y            "225.7451593432695"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/id44122d0/Point/4b829d51c096d627dd2fdcc2d4531bd0>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/id44122d0> ;
        gpml:graphRef     "b2571" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "1009.8240136268855"^^xsd:double ;
        gpml:y            "767.4005343432679"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/addfd>
        rdf:type                 gpml:Interaction ;
        dcterms:isPartOf         <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:biopaxRef           "d01" ;
        gpml:color               "0" ;
        gpml:connectorType       "Straight" ;
        gpml:graphId             "addfd" ;
        gpml:hasAnchor           <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/addfd/Anchor/eee16> ;
        gpml:hasPoint            <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/addfd/Point/f93ed51351ee80ec16a3d974169d2f7a> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/addfd/Point/b9f36a7e84235315951113464cbb3da2> ;
        gpml:hasPublicationXref  <https://identifiers.org/pubmed/17660942> ;
        gpml:lineStyle           "Solid" ;
        gpml:lineThickness       "1.0"^^xsd:double ;
        gpml:zorder              "33050"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/idaef5ff69>
        rdf:type            gpml:GraphicalLine ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:color          "0" ;
        gpml:connectorType  "Elbow" ;
        gpml:graphId        "idaef5ff69" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/idaef5ff69/Point/7b11831d62d5e032b9ecb5cc1251805a> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/idaef5ff69/Point/51e8d45e729750a54d0c832a181c27d1> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/e2019/Point/eeb1e2e4a33f742f4528a8868b2718d4>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/e2019> ;
        gpml:graphRef     "f20f8" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "280.1352282361001"^^xsd:double ;
        gpml:y            "114.31942692162714"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/DataNode/d9f15>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:align           "Center" ;
        gpml:centerX         "1262.7213325829373"^^xsd:double ;
        gpml:centerY         "313.134188506874"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "d9f15" ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "WRN" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "90.0"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000165392" ;
        gpml:zorder          "32819"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/addfd/Point/f93ed51351ee80ec16a3d974169d2f7a>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/addfd> ;
        gpml:graphRef     "e2c06" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "220.13352255335928"^^xsd:double ;
        gpml:y            "480.858960351958"^^xsd:double .

<https://identifiers.org/pubmed/21639948>
        rdf:type          gpml:PublicationXref ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/de018> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/deba7> ;
        gpml:database     "Pubmed" ;
        gpml:id           "21639948" .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/a8443>
        rdf:type            gpml:GraphicalLine ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "a8443" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/a8443/Point/6b1dd93a21aa65c009871bf4f848afce> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/a8443/Point/711d7f2c5d60a311edb5ed96f1202dd1> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<https://identifiers.org/pubmed/30742913>
        rdf:type          gpml:PublicationXref ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/cb3ec> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/id2699c0dc> ;
        gpml:database     "Pubmed" ;
        gpml:id           "30742913" .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/e5979/Point/a1b9962d2ab7d3115240a41a93e44eee>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/e5979> ;
        gpml:graphRef     "d0a52" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "220.13352255336065"^^xsd:double ;
        gpml:y            "815.2656774210659"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/a507b/Point/968757e91fbdf8af9d64ef142ed2c59a>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/a507b> ;
        gpml:graphRef     "d7ddc" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "1049.9563325829445"^^xsd:double ;
        gpml:y            "254.2451593432695"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/DataNode/b5858>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Group/aa473> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:align           "Center" ;
        gpml:centerX         "220.13352255336065"^^xsd:double ;
        gpml:centerY         "776.9214410311084"^^xsd:double ;
        gpml:color           "ff" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "b5858" ;
        gpml:groupRef        "aa473" ;
        gpml:height          "25.000000000000043"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "Farnesyl-L-cysteine" ;
        gpml:type            "Metabolite" ;
        gpml:valign          "Middle" ;
        gpml:width           "123.29727333743013"^^xsd:double ;
        gpml:xrefDataSource  "ChEBI" ;
        gpml:xrefId          "CHEBI:86019" ;
        gpml:zorder          "33075"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/DataNode/fab90>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:align           "Center" ;
        gpml:centerX         "363.62816970558754"^^xsd:double ;
        gpml:centerY         "595.2904956771363"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "fab90" ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "ZMPSTE24" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "90.0"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000084073" ;
        gpml:zorder          "33071"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/e6b93/Point/f2f2bb41b7931e514f432fde09f78ae4>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/e6b93> ;
        gpml:graphRef     "c5878" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "1385.2200825829516"^^xsd:double ;
        gpml:y            "407.89158903026265"^^xsd:double .

<https://identifiers.org/pubmed/19956441>
        rdf:type          gpml:PublicationXref ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/a7c8e> ;
        gpml:database     "Pubmed" ;
        gpml:id           "19956441" .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Shape/a9919>
        rdf:type             gpml:shape ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:align           "Center" ;
        gpml:centerX         "67.80402985074642"^^xsd:double ;
        gpml:centerY         "239.47287313432795"^^xsd:double ;
        gpml:color           "cc0033" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "a9919" ;
        gpml:height          "21.77026119402891"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shape           "0.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "x" ;
        gpml:valign          "Middle" ;
        gpml:width           "80.32429104477606"^^xsd:double ;
        gpml:zorder          "16384"^^xsd:long .

<https://identifiers.org/pubmed/27437668>
        rdf:type          gpml:PublicationXref ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/b5342> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/id2c06b01e> ;
        gpml:database     "Pubmed" ;
        gpml:id           "27437668" .

<https://identifiers.org/pubmed/26993153>
        rdf:type          gpml:PublicationXref ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/e3c84> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/bcab1> ;
        gpml:database     "Pubmed" ;
        gpml:id           "26993153" .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/DataNode/a51ed>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:align           "Center" ;
        gpml:centerX         "588.2626198963845"^^xsd:double ;
        gpml:centerY         "577.1992040844311"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "a51ed" ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "PPARG" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "90.0"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000132170" ;
        gpml:zorder          "32768"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/DataNode/d0d0b>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:align           "Center" ;
        gpml:centerX         "971.132582582951"^^xsd:double ;
        gpml:centerY         "456.8916621814047"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "d0d0b" ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "SPRTN" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "90.0"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000010072" ;
        gpml:zorder          "32810"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/ida223d25e/Point/43039df2212c681e38f9824d33b2de66>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/ida223d25e> ;
        gpml:graphRef     "a84d6" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "1009.8240136268855"^^xsd:double ;
        gpml:y            "635.1772189135808"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/DataNode/f50aa>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Group/d7512> ;
        gpml:align           "Center" ;
        gpml:centerX         "418.3943397270418"^^xsd:double ;
        gpml:centerY         "894.839688844668"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "f50aa" ;
        gpml:groupRef        "d7512" ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "Lamin A" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "90.0"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000160789" ;
        gpml:zorder          "33185"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/e87cd>
        rdf:type                 gpml:GraphicalLine ;
        dcterms:isPartOf         <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:biopaxRef           "d72" , "a00" , "fcf" ;
        gpml:color               "ff0000" ;
        gpml:connectorType       "Elbow" ;
        gpml:graphId             "e87cd" ;
        gpml:hasPoint            <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/e87cd/Point/5edc9308e651a83869d6b052b2255a0a> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/e87cd/Point/a52ba3edd4b491bd12bd7663d00580ae> ;
        gpml:hasPublicationXref  <https://identifiers.org/pubmed/29989768> , <https://identifiers.org/pubmed/18796515> , <https://identifiers.org/pubmed/28476236> ;
        gpml:lineStyle           "Solid" ;
        gpml:lineThickness       "1.0"^^xsd:double ;
        gpml:zorder              "33188"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Label/e8159>
        rdf:type             gpml:Label ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:align           "Center" ;
        gpml:centerX         "614.3121954560808"^^xsd:double ;
        gpml:centerY         "618.6444067062661"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "e8159" ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:href            "" ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "None" ;
        gpml:textlabel       "Oxidative lesions" ;
        gpml:valign          "Middle" ;
        gpml:width           "96.93609141790967"^^xsd:double ;
        gpml:zorder          "28672"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/b8dbb/Point/2e5cd9a7156e1e6a79a03f17e9b7142d>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/b8dbb> ;
        gpml:graphRef     "e2665" ;
        gpml:relX         "1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "408.62816970558765"^^xsd:double ;
        gpml:y            "815.508908317835"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/iddaec0a84/Point/b32473ce3a15e4b373abaf33051c2f17>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/iddaec0a84> ;
        gpml:graphRef     "f626b" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "900.015082582947"^^xsd:double ;
        gpml:y            "225.7451593432695"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/DataNode/b8ed0>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:align           "Center" ;
        gpml:centerX         "1385.2200825829514"^^xsd:double ;
        gpml:centerY         "313.134188506874"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "b8ed0" ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "RECQL" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "90.0"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000004700" ;
        gpml:zorder          "32768"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/f5767/Point/516873610703e3182bf645ec4b68a39e>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/f5767> ;
        gpml:graphRef     "d6538" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "579.0150825829472"^^xsd:double ;
        gpml:y            "254.2451593432695"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/e2019>
        rdf:type            gpml:GraphicalLine ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "e2019" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/e2019/Point/eeb1e2e4a33f742f4528a8868b2718d4> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/e2019/Point/3acd59a38467fc8ef55d3631d24f6579> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Comment/d871bc837eb13424720e53a67e761ab7>
        rdf:type          gpml:Comment ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/id750caaa3> ;
        gpml:commentText  "uncertain if insulin is regulated by the potassium channels" .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/ide242ce3a/Point/bfe91c862409a7b72b81fa17c23450cb>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/ide242ce3a> ;
        gpml:graphRef     "ac0c0" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "588.2626198963845"^^xsd:double ;
        gpml:y            "442.0021506999701"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Group/b27ab>
        rdf:type          gpml:Group ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:graphId      "b27ab" ;
        gpml:groupId      "b27ab" ;
        gpml:style        "Complex" .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/a3f39>
        rdf:type                 gpml:GraphicalLine ;
        dcterms:isPartOf         <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:biopaxRef           "b52" ;
        gpml:color               "0" ;
        gpml:connectorType       "Straight" ;
        gpml:graphId             "a3f39" ;
        gpml:hasPoint            <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/a3f39/Point/e11c267db377cd6cc513ffb826b59890> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/a3f39/Point/fd1ddab184100345283847648f4cd9bf> ;
        gpml:hasPublicationXref  <https://identifiers.org/pubmed/31796734> ;
        gpml:lineStyle           "Solid" ;
        gpml:lineThickness       "1.0"^^xsd:double ;
        gpml:zorder              "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/id17b91f80>
        rdf:type            gpml:GraphicalLine ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:color          "0" ;
        gpml:connectorType  "Elbow" ;
        gpml:graphId        "id17b91f80" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/id17b91f80/Point/ad01556e22fd8d730757efe9c1139ee6> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/id17b91f80/Point/86fe90a2db0ac9ab1875e2e04230639a> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/id2c06b01e>
        rdf:type                 gpml:Interaction ;
        dcterms:isPartOf         <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:biopaxRef           "d31" , "c20" ;
        gpml:color               "0" ;
        gpml:connectorType       "Elbow" ;
        gpml:graphId             "id2c06b01e" ;
        gpml:hasPoint            <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/id2c06b01e/Point/2ff6cb254f4d58bfa646637b27304bf2> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/id2c06b01e/Point/4d9a6f5daea78e32ec265e9a3dcae7a8> ;
        gpml:hasPublicationXref  <https://identifiers.org/pubmed/32439107> , <https://identifiers.org/pubmed/27437668> ;
        gpml:lineStyle           "Solid" ;
        gpml:lineThickness       "1.0"^^xsd:double ;
        gpml:zorder              "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/abc5a/Anchor/d0a52>
        rdf:type          gpml:Anchor ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/abc5a> ;
        gpml:graphId      "d0a52" ;
        gpml:position     "0.09786660564692382"^^xsd:double ;
        gpml:shape        "None" .

<https://identifiers.org/pubmed/12921235>
        rdf:type          gpml:PublicationXref ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/e88d6> ;
        gpml:database     "Pubmed" ;
        gpml:id           "12921235" .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/e87cd/Point/a52ba3edd4b491bd12bd7663d00580ae>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/e87cd> ;
        gpml:graphRef     "f4495" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "475.01508258294723"^^xsd:double ;
        gpml:y            "254.2451593432695"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Group/b2571>
        rdf:type          gpml:Group ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:graphId      "b2571" ;
        gpml:groupId      "b2571" ;
        gpml:style        "Complex" .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/id364035b0>
        rdf:type                 gpml:Interaction ;
        dcterms:isPartOf         <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:biopaxRef           "b08" , "c20" ;
        gpml:color               "0" ;
        gpml:connectorType       "Straight" ;
        gpml:graphId             "id364035b0" ;
        gpml:hasPoint            <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/id364035b0/Point/393822f214e75c940a2a7e283a764efa> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/id364035b0/Point/a60d92c93621e173b488516560d5e8eb> ;
        gpml:hasPublicationXref  <https://identifiers.org/pubmed/29381406> , <https://identifiers.org/pubmed/32439107> ;
        gpml:lineStyle           "Solid" ;
        gpml:lineThickness       "1.0"^^xsd:double ;
        gpml:zorder              "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Group/d7512>
        rdf:type          gpml:Group ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:graphId      "d7512" ;
        gpml:groupId      "d7512" ;
        gpml:style        "Complex" .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/a5a0b>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:color          "0" ;
        gpml:connectorType  "Elbow" ;
        gpml:graphId        "a5a0b" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/a5a0b/Point/dbe91860511544b264c1d84d6fb50503> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/a5a0b/Point/45d31ed9a88a424a27c9ff702d35a73a> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "33064"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/DataNode/aaaed>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:align           "Center" ;
        gpml:centerX         "588.2626198963845"^^xsd:double ;
        gpml:centerY         "394.4405835357905"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "aaaed" ;
        gpml:hasComment      <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Comment/8fa6ba8ead2ae3a877f73697c5e5bbc8> ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "KCNJ6" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "90.0"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000157542" ;
        gpml:zorder          "32815"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Label/ac0c0>
        rdf:type             gpml:Label ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:align           "Center" ;
        gpml:centerX         "588.2626198963845"^^xsd:double ;
        gpml:centerY         "454.5021506999701"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "ac0c0" ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:href            "" ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "None" ;
        gpml:textlabel       "K+ influx" ;
        gpml:valign          "Middle" ;
        gpml:width           "76.35918711962745"^^xsd:double ;
        gpml:zorder          "32799"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/f5767>
        rdf:type                 gpml:GraphicalLine ;
        dcterms:isPartOf         <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:biopaxRef           "a00" , "d72" , "fcf" ;
        gpml:color               "ff0000" ;
        gpml:connectorType       "Elbow" ;
        gpml:graphId             "f5767" ;
        gpml:hasPoint            <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/f5767/Point/516873610703e3182bf645ec4b68a39e> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/f5767/Point/e3632abba3c3601356cd0eadf5dd4256> ;
        gpml:hasPublicationXref  <https://identifiers.org/pubmed/28476236> , <https://identifiers.org/pubmed/18796515> , <https://identifiers.org/pubmed/29989768> ;
        gpml:lineStyle           "Solid" ;
        gpml:lineThickness       "1.0"^^xsd:double ;
        gpml:zorder              "32773"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/id42186e6/Point/4b1eb853cb63ac2f8dcb5cd4cbae7a73>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/id42186e6> ;
        gpml:graphRef     "e8fb3" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "840.1330544445436"^^xsd:double ;
        gpml:y            "181.0285874649378"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/DataNode/fc0e0>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Group/a762f> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:align           "Center" ;
        gpml:centerX         "220.13352255335934"^^xsd:double ;
        gpml:centerY         "668.1557792395624"^^xsd:double ;
        gpml:color           "ff" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "fc0e0" ;
        gpml:groupRef        "a762f" ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "Farnesyl-L-cysteine" ;
        gpml:type            "Metabolite" ;
        gpml:valign          "Middle" ;
        gpml:width           "123.29727333743011"^^xsd:double ;
        gpml:xrefDataSource  "ChEBI" ;
        gpml:xrefId          "CHEBI:86019" ;
        gpml:zorder          "33082"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/idaef5ff69/Point/7b11831d62d5e032b9ecb5cc1251805a>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/idaef5ff69> ;
        gpml:graphRef     "e8fb3" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "840.1330544445436"^^xsd:double ;
        gpml:y            "181.0285874649378"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/ae707/Point/a1ad7ebbf25b42c2f87ed84cc9c8b137>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/ae707> ;
        gpml:graphRef     "bd4e6" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "318.62816970558754"^^xsd:double ;
        gpml:y            "706.862015574959"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Group/e2c06>
        rdf:type          gpml:Group ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:graphId      "e2c06" ;
        gpml:groupId      "e2c06" ;
        gpml:style        "Complex" .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/c4c53/Anchor/c6b9d>
        rdf:type          gpml:Anchor ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/c4c53> ;
        gpml:graphId      "c6b9d" ;
        gpml:position     "0.4"^^xsd:double ;
        gpml:shape        "None" .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/a14a3>
        rdf:type            gpml:GraphicalLine ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:color          "ff0000" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "a14a3" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/a14a3/Point/9f8907a1555355b335444189567271b2> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/a14a3/Point/1f1151f052861fad436de5eac858b903> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "33100"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/DataNode/a84d6>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:align           "Center" ;
        gpml:centerX         "1009.8240136268856"^^xsd:double ;
        gpml:centerY         "622.6772189135808"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "a84d6" ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "Fibrillin-1" ;
        gpml:type            "Protein" ;
        gpml:valign          "Middle" ;
        gpml:width           "90.0"^^xsd:double ;
        gpml:xrefDataSource  "UniProtKB" ;
        gpml:xrefId          "F6U495" ;
        gpml:zorder          "32814"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Shape/e6682>
        rdf:type             gpml:shape ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:align           "Center" ;
        gpml:centerX         "200.61801141188997"^^xsd:double ;
        gpml:centerY         "164.5223888339489"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "e6682" ;
        gpml:height          "211.18022233210223"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shape           "0.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "" ;
        gpml:valign          "Middle" ;
        gpml:width           "368.7715544468414"^^xsd:double ;
        gpml:zorder          "33101"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/DataNode/df33d>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:align           "Center" ;
        gpml:centerX         "870.2545825829528"^^xsd:double ;
        gpml:centerY         "576.8216088443393"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "df33d" ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "FBN1" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "90.0"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000166147" ;
        gpml:zorder          "32806"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/cb43d/Point/b42d27560b00d4e16d80821ccda2e6d2>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/cb43d> ;
        gpml:graphRef     "ffc08" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "458.01137633331115"^^xsd:double ;
        gpml:y            "333.26799567713556"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/DataNode/bd4e6>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:align           "Center" ;
        gpml:centerX         "363.62816970558754"^^xsd:double ;
        gpml:centerY         "706.862015574959"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "bd4e6" ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "ICMT" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "90.0"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000116237" ;
        gpml:zorder          "33077"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/c4c53/Point/69af5a964a34b796364d4121fc80151e>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/c4c53> ;
        gpml:graphRef     "e2c06" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "220.13352255335928"^^xsd:double ;
        gpml:y            "579.858960351958"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/idc66823a3/Point/195d805478fb4c5a2396ceb99b4fd51c>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/idc66823a3> ;
        gpml:graphRef     "eb3f8" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "1262.7213325829373"^^xsd:double ;
        gpml:y            "225.7451593432695"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/b2689/Point/b6db4e318069d5816ae9844b0d46f8fe>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/b2689> ;
        gpml:graphRef     "a28e8" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "734.8600303517707"^^xsd:double ;
        gpml:y            "618.8299985013987"^^xsd:double .

<https://identifiers.org/pubmed/31796734>
        rdf:type          gpml:PublicationXref ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/bf102> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/b2689> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/a3f39> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/ida340ce1> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/id622c631d> ;
        gpml:database     "Pubmed" ;
        gpml:id           "31796734" .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/ide614247e>
        rdf:type            gpml:GraphicalLine ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:color          "0" ;
        gpml:connectorType  "Elbow" ;
        gpml:graphId        "ide614247e" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/ide614247e/Point/25311b0161f70c572597424120ec6a8b> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/ide614247e/Point/5ceef0c2a21c2121de8aebd5da5dc62c> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/b8dbb/Point/7152a79482257e21237e8d61557e9b30>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/b8dbb> ;
        gpml:graphRef     "ffc08" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "458.01137633331115"^^xsd:double ;
        gpml:y            "333.26799567713556"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/DataNode/d2328>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Group/f219c> ;
        gpml:align           "Center" ;
        gpml:centerX         "1009.8240136268856"^^xsd:double ;
        gpml:centerY         "919.390832850731"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "d2328" ;
        gpml:groupRef        "f219c" ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "SMAD2" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "90.0"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000175387" ;
        gpml:zorder          "33093"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/id622c631d/Point/4dee1c60801324531078738ca2b1f335>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/id622c631d> ;
        gpml:graphRef     "e0bcb" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "734.8600303517707"^^xsd:double ;
        gpml:y            "687.5261901268501"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Comment/70ea7a58a8a352687d2bfb7e6a7f5431>
        rdf:type          gpml:Comment ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170/DataNode/e8a6f> ;
        gpml:commentText  "DNA-protein cross-links" .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/e6447/Point/2065203a3334a73c2ebf6cf17e2dc3b4>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/e6447> ;
        gpml:graphRef     "c6b9d" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "220.1335225533593"^^xsd:double ;
        gpml:y            "595.3776879070003"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/c363f>
        rdf:type                 gpml:GraphicalLine ;
        dcterms:isPartOf         <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:biopaxRef           "bcd" ;
        gpml:color               "0" ;
        gpml:connectorType       "Straight" ;
        gpml:graphId             "c363f" ;
        gpml:hasPoint            <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/c363f/Point/1a912f3fb4b8c26812a91b0ddbb1556b> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/c363f/Point/c8bac20697a75afd636f353874987899> ;
        gpml:hasPublicationXref  <https://identifiers.org/pubmed/25727005> ;
        gpml:lineStyle           "Solid" ;
        gpml:lineThickness       "1.0"^^xsd:double ;
        gpml:zorder              "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/id2699c0dc/Point/51d28491277458fbe1fa2043d5db3d45>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/id2699c0dc> ;
        gpml:graphRef     "e7757" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "689.8600303517707"^^xsd:double ;
        gpml:y            "577.1992040844311"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/DataNode/e7926>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Group/e2c06> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:align           "Center" ;
        gpml:centerX         "220.13352255335928"^^xsd:double ;
        gpml:centerY         "555.358960351958"^^xsd:double ;
        gpml:color           "ff" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "e7926" ;
        gpml:groupRef        "e2c06" ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "Farnesyl" ;
        gpml:type            "Metabolite" ;
        gpml:valign          "Middle" ;
        gpml:width           "90.0"^^xsd:double ;
        gpml:xrefDataSource  "ChEBI" ;
        gpml:xrefId          "CHEBI:86019" ;
        gpml:zorder          "33059"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Label/cb80e>
        rdf:type             gpml:Label ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:align           "Center" ;
        gpml:centerX         "325.1352282361001"^^xsd:double ;
        gpml:centerY         "81.96438789743581"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "cb80e" ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:href            "" ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "None" ;
        gpml:textlabel       "Conversion" ;
        gpml:valign          "Middle" ;
        gpml:width           "90.0"^^xsd:double ;
        gpml:zorder          "28672"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/abc5a/Point/398abce50fb957bd1fe8b67cfbe1de98>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/abc5a> ;
        gpml:graphRef     "aa473" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "220.13352255336065"^^xsd:double ;
        gpml:y            "801.4214410311083"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/e5979>
        rdf:type                 gpml:Interaction ;
        dcterms:isPartOf         <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:biopaxRef           "d01" ;
        gpml:color               "0" ;
        gpml:connectorType       "Straight" ;
        gpml:graphId             "e5979" ;
        gpml:hasPoint            <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/e5979/Point/5999a36205813a6f52935867a22375a4> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/e5979/Point/a1b9962d2ab7d3115240a41a93e44eee> ;
        gpml:hasPublicationXref  <https://identifiers.org/pubmed/17660942> ;
        gpml:lineStyle           "Solid" ;
        gpml:lineThickness       "1.0"^^xsd:double ;
        gpml:zorder              "33055"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/e654c/Point/9eeb107c9a984ebf5114e9b6a5da3b1e>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/e654c> ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "217.86307864654944"^^xsd:double ;
        gpml:y            "175.154"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/cb3ec/Point/d19a93ec7d3c4d913c73e2957db65807>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/cb3ec> ;
        gpml:graphRef     "fc6f0" ;
        gpml:relX         "1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "265.1335225533593"^^xsd:double ;
        gpml:y            "320.7679956771355"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/a1db9/Point/57b16759870b55cb4dda2db1aa040508>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/a1db9> ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "734.8600303517707"^^xsd:double ;
        gpml:y            "564.6992040844311"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/DataNode/bf030>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Group/aa473> ;
        gpml:align           "Center" ;
        gpml:centerX         "220.1335225533583"^^xsd:double ;
        gpml:centerY         "752.6392493777371"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "bf030" ;
        gpml:groupRef        "aa473" ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "Prelamin-A/C" ;
        gpml:type            "Protein" ;
        gpml:valign          "Middle" ;
        gpml:width           "89.33385458598717"^^xsd:double ;
        gpml:xrefDataSource  "UniProtKB" ;
        gpml:xrefId          "P02545" ;
        gpml:zorder          "33070"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Shape/f8329>
        rdf:type             gpml:shape ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:align           "Center" ;
        gpml:centerX         "67.80402985074642"^^xsd:double ;
        gpml:centerY         "167.85635727611913"^^xsd:double ;
        gpml:color           "ff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "f8329" ;
        gpml:height          "21.77026119402891"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shape           "0.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "x" ;
        gpml:valign          "Middle" ;
        gpml:width           "80.32429104477606"^^xsd:double ;
        gpml:zorder          "33191"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/abc5a/Point/88cf3bbafe1c06a7e51e7d8be6f42a66>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/abc5a> ;
        gpml:graphRef     "ec7b0" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "301.64004469889846"^^xsd:double ;
        gpml:y            "861.3751881821663"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/DataNode/e7757>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:align           "Center" ;
        gpml:centerX         "734.8600303517707"^^xsd:double ;
        gpml:centerY         "577.1992040844311"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "e7757" ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "BANF1" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "90.0"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000175334" ;
        gpml:zorder          "32808"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/ad194/Point/47892db9c36e660fc38bd4f9bdb1a266>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/ad194> ;
        gpml:graphRef     "d1c01" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "1121.5877065374643"^^xsd:double ;
        gpml:y            "532.726077556159"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/cb43d/Point/9f76dbf219d779ee6e963bc9dcea2d88>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/cb43d> ;
        gpml:graphRef     "fab90" ;
        gpml:relX         "1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "408.62816970558754"^^xsd:double ;
        gpml:y            "595.2904956771363"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/bcab1/Point/593f1b15fd4b1d1801979be75fef2a46>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/bcab1> ;
        gpml:graphRef     "b8ed0" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "1340.2200825829514"^^xsd:double ;
        gpml:y            "313.134188506874"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/ide242ce3a/Point/35832b00dbcac11cf6435c6bf20d79d5>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/ide242ce3a> ;
        gpml:graphRef     "aaaed" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "588.2626198963845"^^xsd:double ;
        gpml:y            "406.9405835357905"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/b3ecb>
        rdf:type                 gpml:Interaction ;
        dcterms:isPartOf         <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:biopaxRef           "d01" ;
        gpml:color               "0" ;
        gpml:connectorType       "Straight" ;
        gpml:graphId             "b3ecb" ;
        gpml:hasAnchor           <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/b3ecb/Anchor/b6c5f> ;
        gpml:hasPoint            <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/b3ecb/Point/ae4b73b61a4b1be506d6f1670c9033d1> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/b3ecb/Point/c1fcedeff16048c020bf6dddfa66d0e8> ;
        gpml:hasPublicationXref  <https://identifiers.org/pubmed/17660942> ;
        gpml:lineStyle           "Solid" ;
        gpml:lineThickness       "1.0"^^xsd:double ;
        gpml:zorder              "33051"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Group/aa473>
        rdf:type          gpml:Group ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:graphId      "aa473" ;
        gpml:groupId      "aa473" ;
        gpml:style        "Complex" .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/DataNode/fc6f0>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:align           "Center" ;
        gpml:centerX         "220.13352255335928"^^xsd:double ;
        gpml:centerY         "320.7679956771355"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "fc6f0" ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "LMNA" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "90.0"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000160789" ;
        gpml:zorder          "33078"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Label/ee52a>
        rdf:type             gpml:Label ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:align           "Center" ;
        gpml:centerX         "280.84389812173316"^^xsd:double ;
        gpml:centerY         "787.5664065147913"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "ee52a" ;
        gpml:height          "21.760087399939728"^^xsd:double ;
        gpml:href            "" ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "None" ;
        gpml:textlabel       "M" ;
        gpml:valign          "Middle" ;
        gpml:width           "44.320782202337526"^^xsd:double ;
        gpml:zorder          "33085"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/c363f/Point/1a912f3fb4b8c26812a91b0ddbb1556b>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/c363f> ;
        gpml:graphRef     "d746d" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "1148.1731217620563"^^xsd:double ;
        gpml:y            "944.2825166193877"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/e3c84/Point/b620cf0922c5c7c252dc318322069c03>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/e3c84> ;
        gpml:graphRef     "c5878" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "1385.2200825829516"^^xsd:double ;
        gpml:y            "382.89158903026265"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/e5223/Point/ab61b2c4d5f19d24a26620989fa50b7>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/e5223> ;
        gpml:graphRef     "aa473" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "220.13352255336065"^^xsd:double ;
        gpml:y            "801.4214410311083"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/ida223d25e/Point/90add8addc6a74b02c177171977fb09f>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/ida223d25e> ;
        gpml:graphRef     "a3ce7" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "1009.8240136268855"^^xsd:double ;
        gpml:y            "685.9505343432669"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/ba127/Point/ba25feaa2387d0f3494dfcae9eb6e61c>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/ba127> ;
        gpml:graphRef     "aaaed" ;
        gpml:relX         "1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "633.2626198963845"^^xsd:double ;
        gpml:y            "394.4405835357905"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/e5223/Point/80791bcf21e28ae5e9a0f157c6c6bc21>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/e5223> ;
        gpml:graphRef     "ff0fb" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "158.38829348851192"^^xsd:double ;
        gpml:y            "861.3751881821663"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/DataNode/d6538>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:align           "Center" ;
        gpml:centerX         "579.0150825829472"^^xsd:double ;
        gpml:centerY         "239.9951593432695"^^xsd:double ;
        gpml:color           "cc3300" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "d6538" ;
        gpml:height          "28.5"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "Hutchinson-Gilford \nProgeria Syndrome" ;
        gpml:type            "Unknown" ;
        gpml:valign          "Middle" ;
        gpml:width           "118.0"^^xsd:double ;
        gpml:xrefDataSource  "Wikidata" ;
        gpml:xrefId          "Q213098" ;
        gpml:zorder          "32768"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/eca08/Point/4b012fe529871b137b78b4e829fefa60>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/eca08> ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "219.59290578358218"^^xsd:double ;
        gpml:y            "241.488"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/ae707/Point/ac1ce30a3eae07dc2c991d3c7de4cda7>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/ae707> ;
        gpml:graphRef     "b6c5f" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "220.13352255335985"^^xsd:double ;
        gpml:y            "706.8491672948323"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/id622c631d/Point/c20641eda94c56ed6243dfc7ba6db7ff>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/id622c631d> ;
        gpml:graphRef     "b27ab" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "734.8600303517707"^^xsd:double ;
        gpml:y            "740.8228139365931"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Label/fcbf9>
        rdf:type             gpml:Label ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:align           "Center" ;
        gpml:centerX         "595.0412415321109"^^xsd:double ;
        gpml:centerY         "919.8396888446678"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "fcbf9" ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:href            "" ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "None" ;
        gpml:textlabel       "Nuclear Lamina" ;
        gpml:valign          "Middle" ;
        gpml:width           "99.75312163957403"^^xsd:double ;
        gpml:zorder          "33066"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/cb3ec>
        rdf:type                 gpml:GraphicalLine ;
        dcterms:isPartOf         <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:biopaxRef           "c3c" , "d72" ;
        gpml:color               "ff0000" ;
        gpml:connectorType       "Straight" ;
        gpml:graphId             "cb3ec" ;
        gpml:hasPoint            <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/cb3ec/Point/120b26b3a316b7e288c6f06858769414> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/cb3ec/Point/d19a93ec7d3c4d913c73e2957db65807> ;
        gpml:hasPublicationXref  <https://identifiers.org/pubmed/29989768> , <https://identifiers.org/pubmed/30742913> ;
        gpml:lineStyle           "Solid" ;
        gpml:lineThickness       "1.0"^^xsd:double ;
        gpml:zorder              "33063"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/ida340ce1/Point/8b94c069feb24a28d87ac9e05d356f15>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/ida340ce1> ;
        gpml:graphRef     "e0bcb" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "734.8600303517707"^^xsd:double ;
        gpml:y            "662.5261901268501"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/de018/Point/5f24139ac797977fa701c963bb38cd71>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/de018> ;
        gpml:graphRef     "fcbf9" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "545.1646807123238"^^xsd:double ;
        gpml:y            "919.8396888446678"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/idaef5ff69/Point/51e8d45e729750a54d0c832a181c27d1>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/idaef5ff69> ;
        gpml:graphRef     "e440d" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "692.573832582949"^^xsd:double ;
        gpml:y            "225.7451593432695"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Label/e8fb3>
        rdf:type             gpml:Label ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:align           "Center" ;
        gpml:centerX         "840.1330544445436"^^xsd:double ;
        gpml:centerY         "160.0268269015578"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "e8fb3" ;
        gpml:height          "42.003521126760006"^^xsd:double ;
        gpml:href            "" ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "None" ;
        gpml:textlabel       "Progeria Associated Lipodystrophy" ;
        gpml:valign          "Middle" ;
        gpml:width           "214.25704225352052"^^xsd:double ;
        gpml:zorder          "32803"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/DataNode/eb3f8>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:align           "Center" ;
        gpml:centerX         "1262.7213325829373"^^xsd:double ;
        gpml:centerY         "239.9951593432695"^^xsd:double ;
        gpml:color           "cc3300" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "eb3f8" ;
        gpml:height          "28.5"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "Werner \nsyndrome" ;
        gpml:type            "Unknown" ;
        gpml:valign          "Middle" ;
        gpml:width           "73.88249999999607"^^xsd:double ;
        gpml:xrefDataSource  "Wikidata" ;
        gpml:xrefId          "Q1154619" ;
        gpml:zorder          "32768"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/DataNode/ec7b0>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:align           "Center" ;
        gpml:centerX         "301.64004469889846"^^xsd:double ;
        gpml:centerY         "873.8751881821663"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "ec7b0" ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "Lamin A" ;
        gpml:type            "Protein" ;
        gpml:valign          "Middle" ;
        gpml:width           "90.0"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000160789" ;
        gpml:zorder          "32768"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/a1db9/Point/51a9f235e8273c54696656dd3113328>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/a1db9> ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "714.8600303517707"^^xsd:double ;
        gpml:y            "489.1726297607657"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/a3f39/Point/e11c267db377cd6cc513ffb826b59890>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/a3f39> ;
        gpml:graphRef     "bddc5" ;
        gpml:relX         "1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "621.2758461119937"^^xsd:double ;
        gpml:y            "777.8742229728698"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/e6b93>
        rdf:type                 gpml:GraphicalLine ;
        dcterms:isPartOf         <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:biopaxRef           "c66" ;
        gpml:color               "0" ;
        gpml:connectorType       "Elbow" ;
        gpml:graphId             "e6b93" ;
        gpml:hasPoint            <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/e6b93/Point/153b46cf919ab9f627c0e042cefb44dc> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/e6b93/Point/f2f2bb41b7931e514f432fde09f78ae4> ;
        gpml:hasPublicationXref  <https://identifiers.org/pubmed/27320729> ;
        gpml:lineStyle           "Solid" ;
        gpml:lineThickness       "1.0"^^xsd:double ;
        gpml:zorder              "32782"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/dea16>
        rdf:type                 gpml:GraphicalLine ;
        dcterms:isPartOf         <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:biopaxRef           "d72" , "fcf" ;
        gpml:color               "ff0000" ;
        gpml:connectorType       "Elbow" ;
        gpml:graphId             "dea16" ;
        gpml:hasPoint            <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/dea16/Point/a9ae11b97d40ed5e22759c23f4edcfab> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/dea16/Point/44e5a453ba78ffd23d4d18aff785f5f7> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/dea16/Point/bf59eecfe5956b2eda2b525cb8a05617> ;
        gpml:hasPublicationXref  <https://identifiers.org/pubmed/28476236> , <https://identifiers.org/pubmed/29989768> ;
        gpml:lineStyle           "Solid" ;
        gpml:lineThickness       "1.0"^^xsd:double ;
        gpml:zorder              "32795"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/id2c06b01e/Point/4d9a6f5daea78e32ec265e9a3dcae7a8>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/id2c06b01e> ;
        gpml:graphRef     "a84d6" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "964.8240136268855"^^xsd:double ;
        gpml:y            "622.6772189135808"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Label/c5878>
        rdf:type             gpml:Label ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:align           "Center" ;
        gpml:centerX         "1385.2200825829516"^^xsd:double ;
        gpml:centerY         "395.39158903026265"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "c5878" ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:href            "" ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "None" ;
        gpml:textlabel       "DNA replication and repair" ;
        gpml:valign          "Middle" ;
        gpml:width           "157.43807379464124"^^xsd:double ;
        gpml:zorder          "32800"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/DataNode/a7d5e>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:align           "Center" ;
        gpml:centerX         "588.2626198963845"^^xsd:double ;
        gpml:centerY         "334.62826412238564"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "a7d5e" ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "GPCR" ;
        gpml:type            "Protein" ;
        gpml:valign          "Middle" ;
        gpml:width           "90.0"^^xsd:double ;
        gpml:xrefDataSource  "UniProtKB" ;
        gpml:xrefId          "A0A0K0PUW7" ;
        gpml:zorder          "32816"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/ide614247e/Point/5ceef0c2a21c2121de8aebd5da5dc62c>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/ide614247e> ;
        gpml:graphRef     "d7ddc" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "1049.9563325829445"^^xsd:double ;
        gpml:y            "225.7451593432695"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/a5a0b/Point/dbe91860511544b264c1d84d6fb50503>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/a5a0b> ;
        gpml:graphRef     "e2f4a" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "301.64004469889846"^^xsd:double ;
        gpml:y            "964.8920111499142"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Label/ea7c9>
        rdf:type             gpml:Label ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:align           "Center" ;
        gpml:centerX         "325.1352282361001"^^xsd:double ;
        gpml:centerY         "142.49077020520951"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "ea7c9" ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:href            "" ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "None" ;
        gpml:textlabel       "Catalysis" ;
        gpml:valign          "Middle" ;
        gpml:width           "90.0"^^xsd:double ;
        gpml:zorder          "28672"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/bcab1>
        rdf:type                 gpml:Interaction ;
        dcterms:isPartOf         <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:biopaxRef           "c59" ;
        gpml:color               "0" ;
        gpml:connectorType       "Elbow" ;
        gpml:graphId             "bcab1" ;
        gpml:hasPoint            <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/bcab1/Point/593f1b15fd4b1d1801979be75fef2a46> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/bcab1/Point/8a6518d8d1eb2d223097b13c79a0d189> ;
        gpml:hasPublicationXref  <https://identifiers.org/pubmed/26993153> ;
        gpml:lineStyle           "Solid" ;
        gpml:lineThickness       "1.0"^^xsd:double ;
        gpml:zorder              "32790"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Label/f0473>
        rdf:type             gpml:Label ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:align           "Center" ;
        gpml:centerX         "1187.9800075355317"^^xsd:double ;
        gpml:centerY         "622.6772189135779"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "f0473" ;
        gpml:height          "40.819239738806004"^^xsd:double ;
        gpml:href            "" ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "None" ;
        gpml:textlabel       "Structural support in\nconncective tissue" ;
        gpml:valign          "Middle" ;
        gpml:width           "132.78460199613437"^^xsd:double ;
        gpml:zorder          "32798"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/ida340ce1/Anchor/a28e8>
        rdf:type          gpml:Anchor ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/ida340ce1> ;
        gpml:graphId      "a28e8" ;
        gpml:position     "0.4"^^xsd:double ;
        gpml:shape        "None" .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/iddfb5e58b>
        rdf:type                 gpml:Interaction ;
        dcterms:isPartOf         <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:biopaxRef           "e6d" ;
        gpml:color               "0" ;
        gpml:connectorType       "Straight" ;
        gpml:graphId             "iddfb5e58b" ;
        gpml:hasPoint            <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/iddfb5e58b/Point/dffaf95d6d30f8732a052d2c0e548d25> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/iddfb5e58b/Point/f596ddbca609bd72774029fbf718a5d> ;
        gpml:hasPublicationXref  <https://identifiers.org/pubmed/27871366> ;
        gpml:lineStyle           "Solid" ;
        gpml:lineThickness       "1.0"^^xsd:double ;
        gpml:zorder              "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/de018/Point/d8d80f5acbf11e6a8ea6d2dbf4a4ee2c>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/de018> ;
        gpml:graphRef     "d7512" ;
        gpml:relX         "1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "475.3943397270418"^^xsd:double ;
        gpml:y            "919.839688844668"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/a8443/Point/711d7f2c5d60a311edb5ed96f1202dd1>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/a8443> ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "215.795"^^xsd:double ;
        gpml:y            "209.71"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/id2b53a9ce/Point/66c40335250bcbb840a6735c5ac5bc63>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/id2b53a9ce> ;
        gpml:graphRef     "a7d5e" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "588.2626198963845"^^xsd:double ;
        gpml:y            "347.12826412238564"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/DataNode/d0ebe>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Group/b2571> ;
        gpml:align           "Center" ;
        gpml:centerX         "1009.8240136268856"^^xsd:double ;
        gpml:centerY         "791.9005343432679"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "d0ebe" ;
        gpml:groupRef        "b2571" ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "SMAD2" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "90.0"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000175387" ;
        gpml:zorder          "32768"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/ecbee/Point/b931b1f07f47c508ff4dacff8b02b0d3>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/ecbee> ;
        gpml:graphRef     "a1689" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "1256.432582582953"^^xsd:double ;
        gpml:y            "444.3916621814047"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/DataNode/f0234>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Group/b0da8> ;
        gpml:align           "Center" ;
        gpml:centerX         "220.13352255335928"^^xsd:double ;
        gpml:centerY         "414.0331615663448"^^xsd:double ;
        gpml:color           "ff" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "f0234" ;
        gpml:groupRef        "b0da8" ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "CAAX" ;
        gpml:type            "Metabolite" ;
        gpml:valign          "Middle" ;
        gpml:width           "90.0"^^xsd:double ;
        gpml:xrefDataSource  "ChEBI" ;
        gpml:xrefId          "CHEBI:15356" ;
        gpml:zorder          "33072"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/id622c631d>
        rdf:type                 gpml:Interaction ;
        dcterms:isPartOf         <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:biopaxRef           "b52" ;
        gpml:color               "0" ;
        gpml:connectorType       "Straight" ;
        gpml:graphId             "id622c631d" ;
        gpml:hasPoint            <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/id622c631d/Point/4dee1c60801324531078738ca2b1f335> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/id622c631d/Point/c20641eda94c56ed6243dfc7ba6db7ff> ;
        gpml:hasPublicationXref  <https://identifiers.org/pubmed/31796734> ;
        gpml:lineStyle           "Solid" ;
        gpml:lineThickness       "1.0"^^xsd:double ;
        gpml:zorder              "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/id1eace11e>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:color          "0" ;
        gpml:connectorType  "Elbow" ;
        gpml:graphId        "id1eace11e" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/id1eace11e/Point/1ed081588ff9b56e2381d90acbff3236> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/id1eace11e/Point/ddd54ef53264bf3c6e316d8841b75e68> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/a7c8e/Point/499986f8c27b61f118c7c49a51c75dfe>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/a7c8e> ;
        gpml:graphRef     "fc6f0" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "220.13352255335928"^^xsd:double ;
        gpml:y            "333.2679956771355"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Label/c4890>
        rdf:type             gpml:Label ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:align           "Center" ;
        gpml:centerX         "325.1352282361001"^^xsd:double ;
        gpml:centerY         "209.7103597574495"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "c4890" ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:href            "" ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "None" ;
        gpml:textlabel       "Inhibition" ;
        gpml:valign          "Middle" ;
        gpml:width           "90.0"^^xsd:double ;
        gpml:zorder          "28672"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/DataNode/e6172>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Group/d7512> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:align           "Center" ;
        gpml:centerX         "418.3943397270418"^^xsd:double ;
        gpml:centerY         "919.8396888446681"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "e6172" ;
        gpml:groupRef        "d7512" ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "Lamin B1" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "90.0"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000113368" ;
        gpml:zorder          "33187"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Group/e2f4a>
        rdf:type          gpml:Group ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:graphId      "e2f4a" ;
        gpml:groupId      "e2f4a" ;
        gpml:style        "Complex" .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/DataNode/ff0fb>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:align           "Center" ;
        gpml:centerX         "158.38829348851192"^^xsd:double ;
        gpml:centerY         "873.8751881821663"^^xsd:double ;
        gpml:color           "ff" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "ff0fb" ;
        gpml:height          "25.000000000000043"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "Farnesyl-L-cysteine" ;
        gpml:type            "Metabolite" ;
        gpml:valign          "Middle" ;
        gpml:width           "123.29727333743013"^^xsd:double ;
        gpml:xrefDataSource  "ChEBI" ;
        gpml:xrefId          "CHEBI:86019" ;
        gpml:zorder          "33086"^^xsd:long .

<https://identifiers.org/pubmed/32439107>
        rdf:type          gpml:PublicationXref ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/b5342> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/ida223d25e> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/id44122d0> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/id364035b0> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/id2c06b01e> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/id2311ce5b> ;
        gpml:database     "Pubmed" ;
        gpml:id           "32439107" .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/id2b53a9ce/Point/abbe7c3cc24704439bd05bc140af6c29>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/id2b53a9ce> ;
        gpml:graphRef     "aaaed" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "588.2626198963845"^^xsd:double ;
        gpml:y            "381.9405835357905"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/id2b53a9ce>
        rdf:type                 gpml:Interaction ;
        dcterms:isPartOf         <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:biopaxRef           "d50" ;
        gpml:color               "0" ;
        gpml:connectorType       "Straight" ;
        gpml:graphId             "id2b53a9ce" ;
        gpml:hasPoint            <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/id2b53a9ce/Point/abbe7c3cc24704439bd05bc140af6c29> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/id2b53a9ce/Point/66c40335250bcbb840a6735c5ac5bc63> ;
        gpml:hasPublicationXref  <https://identifiers.org/pubmed/25620207> ;
        gpml:lineStyle           "Solid" ;
        gpml:lineThickness       "1.0"^^xsd:double ;
        gpml:zorder              "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/DataNode/f6307>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Group/f219c> ;
        gpml:align           "Center" ;
        gpml:centerX         "1009.8240136268856"^^xsd:double ;
        gpml:centerY         "969.390832850731"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "f6307" ;
        gpml:groupRef        "f219c" ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "SMAD4" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "90.0"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000141646" ;
        gpml:zorder          "33094"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/idab17cda9/Point/17ece6d7131461bf9a8c714950f48eed>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/idab17cda9> ;
        gpml:graphRef     "e8a6f" ;
        gpml:relX         "1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "1154.5009115867033"^^xsd:double ;
        gpml:y            "456.8916621814047"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Label/bf9db>
        rdf:type             gpml:Label ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:align           "Center" ;
        gpml:centerX         "143.54783518657274"^^xsd:double ;
        gpml:centerY         "109.45789536134468"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "bf9db" ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:href            "" ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "None" ;
        gpml:textlabel       "Mutations" ;
        gpml:valign          "Middle" ;
        gpml:width           "55.69741551544408"^^xsd:double ;
        gpml:zorder          "33102"^^xsd:long .

<https://identifiers.org/pubmed/18796515>
        rdf:type          gpml:PublicationXref ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/e87cd> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/f5767> ;
        gpml:database     "Pubmed" ;
        gpml:id           "18796515" .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/id17b91f80/Point/86fe90a2db0ac9ab1875e2e04230639a>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/id17b91f80> ;
        gpml:graphRef     "e8fb3" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "840.1330544445436"^^xsd:double ;
        gpml:y            "181.0285874649378"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/d812e>
        rdf:type            gpml:GraphicalLine ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "d812e" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/d812e/Point/1b14860bb0400ed71ce0d97ad9c695b5> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/d812e/Point/230f48bd3bc54434fdd6ade86b9587a2> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<https://identifiers.org/pubmed/25727005>
        rdf:type          gpml:PublicationXref ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/c363f> ;
        gpml:database     "Pubmed" ;
        gpml:id           "25727005" .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/a5ff1/Point/c9c2796182d59e58bae2d64a34df5188>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/a5ff1> ;
        gpml:graphRef     "eee16" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "220.13352255335928"^^xsd:double ;
        gpml:y            "455.4634810805901"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/bf102/Point/e4d6c28bdb8004dfac4c4783f7791535>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/bf102> ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "587.8262036198581"^^xsd:double ;
        gpml:y            "705.7569296375267"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/bf102>
        rdf:type                 gpml:GraphicalLine ;
        dcterms:isPartOf         <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:biopaxRef           "b52" ;
        gpml:color               "0" ;
        gpml:connectorType       "Elbow" ;
        gpml:graphId             "bf102" ;
        gpml:hasPoint            <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/bf102/Point/e4d6c28bdb8004dfac4c4783f7791535> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/bf102/Point/3c1039fd520c5974a082e3f6261e6132> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/bf102/Point/7bef0423abf60d65ebf7b3ab70991167> ;
        gpml:hasPublicationXref  <https://identifiers.org/pubmed/31796734> ;
        gpml:lineStyle           "Solid" ;
        gpml:lineThickness       "1.0"^^xsd:double ;
        gpml:zorder              "12288"^^xsd:long .

<https://identifiers.org/pubmed/32153505>
        rdf:type          gpml:PublicationXref ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/ad194> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/id61369ff8> ;
        gpml:database     "Pubmed" ;
        gpml:id           "32153505" .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/idc66823a3>
        rdf:type            gpml:GraphicalLine ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:color          "0" ;
        gpml:connectorType  "Elbow" ;
        gpml:graphId        "idc66823a3" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/idc66823a3/Point/918f861f1c3347d20427d9a2c0367ccc> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/idc66823a3/Point/195d805478fb4c5a2396ceb99b4fd51c> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/DataNode/e8a6f>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:align           "Center" ;
        gpml:centerX         "1109.5009115867033"^^xsd:double ;
        gpml:centerY         "456.8916621814047"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "e8a6f" ;
        gpml:hasComment      <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Comment/70ea7a58a8a352687d2bfb7e6a7f5431> ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "DPC" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "90.0"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000168631" ;
        gpml:zorder          "32807"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/id42186e6/Point/c36eb8716848fc441a93dd82b326bdc1>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/id42186e6> ;
        gpml:graphRef     "e12e0" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "801.0738325829489"^^xsd:double ;
        gpml:y            "225.7451593432695"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/d812e/Point/1b14860bb0400ed71ce0d97ad9c695b5>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/d812e> ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "218.583803457894"^^xsd:double ;
        gpml:y            "142.491"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/a99e0>
        rdf:type            gpml:Interaction ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:color          "0" ;
        gpml:connectorType  "Elbow" ;
        gpml:graphId        "a99e0" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/a99e0/Point/814d3b90b3c646a699b556684bca1f6f> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/a99e0/Point/a4350e27909f448c9c4d7ac14ce64985> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "33189"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/deba7>
        rdf:type                 gpml:Interaction ;
        dcterms:isPartOf         <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:biopaxRef           "d58" ;
        gpml:color               "0" ;
        gpml:connectorType       "Elbow" ;
        gpml:graphId             "deba7" ;
        gpml:hasPoint            <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/deba7/Point/9f9730260fa59eee9f604777be316b27> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/deba7/Point/57e8ca90e3b7f87577687536fb84f407> ;
        gpml:hasPublicationXref  <https://identifiers.org/pubmed/21639948> ;
        gpml:lineStyle           "Solid" ;
        gpml:lineThickness       "1.0"^^xsd:double ;
        gpml:zorder              "33061"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Label/d1c01>
        rdf:type             gpml:Label ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:align           "Center" ;
        gpml:centerX         "1187.9800075355317"^^xsd:double ;
        gpml:centerY         "532.726077556159"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "d1c01" ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:href            "" ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "None" ;
        gpml:textlabel       "Glucose homeostasis" ;
        gpml:valign          "Middle" ;
        gpml:width           "132.78460199613426"^^xsd:double ;
        gpml:zorder          "32805"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/idab17cda9>
        rdf:type                 gpml:Interaction ;
        dcterms:isPartOf         <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:biopaxRef           "e6d" ;
        gpml:color               "0" ;
        gpml:connectorType       "Straight" ;
        gpml:graphId             "idab17cda9" ;
        gpml:hasPoint            <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/idab17cda9/Point/7fa56b6715d26a66efc5044d86a3d659> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/idab17cda9/Point/17ece6d7131461bf9a8c714950f48eed> ;
        gpml:hasPublicationXref  <https://identifiers.org/pubmed/27871366> ;
        gpml:lineStyle           "Solid" ;
        gpml:lineThickness       "1.0"^^xsd:double ;
        gpml:zorder              "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Group/f219c>
        rdf:type          gpml:Group ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:graphId      "f219c" ;
        gpml:groupId      "f219c" ;
        gpml:style        "Complex" .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/e3c84/Point/337d092ad2f6d7d22089aaa2c12f3249>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/e3c84> ;
        gpml:graphRef     "b8ed0" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "1385.2200825829514"^^xsd:double ;
        gpml:y            "325.634188506874"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/b3ecb/Point/ae4b73b61a4b1be506d6f1670c9033d1>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/b3ecb> ;
        gpml:graphRef     "a762f" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "220.13352255335934"^^xsd:double ;
        gpml:y            "692.6557792395624"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/a8443/Point/6b1dd93a21aa65c009871bf4f848afce>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/a8443> ;
        gpml:graphRef     "c4890" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "280.1352282361001"^^xsd:double ;
        gpml:y            "209.7103597574495"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/bf07c>
        rdf:type            gpml:GraphicalLine ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:color          "0" ;
        gpml:connectorType  "Straight" ;
        gpml:graphId        "bf07c" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/bf07c/Point/9a11a5f75c0e95f15e73713b5b5ade72> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/bf07c/Point/66eea507f23830174f123e4050bddd99> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/bf102/Point/3c1039fd520c5974a082e3f6261e6132>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/bf102> ;
        gpml:graphRef     "bddc5" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "561.3402117836355"^^xsd:double ;
        gpml:y            "765.3742229728698"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/addfd/Point/b9f36a7e84235315951113464cbb3da2>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/addfd> ;
        gpml:graphRef     "b0da8" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "220.13352255335928"^^xsd:double ;
        gpml:y            "438.5331615663448"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/DataNode/d7ddc>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:align           "Center" ;
        gpml:centerX         "1049.9563325829445"^^xsd:double ;
        gpml:centerY         "239.9951593432695"^^xsd:double ;
        gpml:color           "cc3300" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "d7ddc" ;
        gpml:height          "28.5"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "Progeroid features-hepatocellular \ncarcinoma predisposition syndrome " ;
        gpml:type            "Unknown" ;
        gpml:valign          "Middle" ;
        gpml:width           "209.88249999999607"^^xsd:double ;
        gpml:xrefDataSource  "Wikidata" ;
        gpml:xrefId          "Q55784868" ;
        gpml:zorder          "32768"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/addfd/Anchor/eee16>
        rdf:type          gpml:Anchor ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/addfd> ;
        gpml:graphId      "eee16" ;
        gpml:position     "0.4"^^xsd:double ;
        gpml:shape        "None" .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/id2311ce5b>
        rdf:type                 gpml:Interaction ;
        dcterms:isPartOf         <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:biopaxRef           "c20" , "b08" ;
        gpml:color               "0" ;
        gpml:connectorType       "Straight" ;
        gpml:graphId             "id2311ce5b" ;
        gpml:hasPoint            <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/id2311ce5b/Point/e93c6510633a9fecde87080ef20ec4c2> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/id2311ce5b/Point/6e0a8d43aa2518213fff16c96db46c6a> ;
        gpml:hasPublicationXref  <https://identifiers.org/pubmed/32439107> , <https://identifiers.org/pubmed/29381406> ;
        gpml:lineStyle           "Solid" ;
        gpml:lineThickness       "1.0"^^xsd:double ;
        gpml:zorder              "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/id2699c0dc>
        rdf:type                 gpml:Interaction ;
        dcterms:isPartOf         <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:biopaxRef           "c3c" ;
        gpml:color               "0" ;
        gpml:connectorType       "Straight" ;
        gpml:graphId             "id2699c0dc" ;
        gpml:hasPoint            <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/id2699c0dc/Point/51d28491277458fbe1fa2043d5db3d45> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/id2699c0dc/Point/53b07c85dfa2d58118444c5b51c8c0d3> ;
        gpml:hasPublicationXref  <https://identifiers.org/pubmed/30742913> ;
        gpml:lineStyle           "Solid" ;
        gpml:lineThickness       "1.0"^^xsd:double ;
        gpml:zorder              "12288"^^xsd:long .

<https://identifiers.org/pubmed/28476236>
        rdf:type          gpml:PublicationXref ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/dea16> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/a1db9> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/dd30c> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/e87cd> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/ba127> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/ecbee> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/f5767> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/a507b> ;
        gpml:database     "Pubmed" ;
        gpml:id           "28476236" .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/ida340ce1>
        rdf:type                 gpml:Interaction ;
        dcterms:isPartOf         <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:biopaxRef           "b52" ;
        gpml:color               "0" ;
        gpml:connectorType       "Straight" ;
        gpml:graphId             "ida340ce1" ;
        gpml:hasAnchor           <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/ida340ce1/Anchor/a28e8> ;
        gpml:hasPoint            <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/ida340ce1/Point/fce0343460a8f27d9aa7232526b25d2e> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/ida340ce1/Point/8b94c069feb24a28d87ac9e05d356f15> ;
        gpml:hasPublicationXref  <https://identifiers.org/pubmed/31796734> ;
        gpml:lineStyle           "Solid" ;
        gpml:lineThickness       "1.0"^^xsd:double ;
        gpml:zorder              "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/DataNode/c5a96>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:align           "Center" ;
        gpml:centerX         "1177.5724325474075"^^xsd:double ;
        gpml:centerY         "804.2613740776685"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "c5a96" ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "SMAD4" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "90.0"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000141646" ;
        gpml:zorder          "32768"^^xsd:long .

<https://identifiers.org/pubmed/27320729>
        rdf:type          gpml:PublicationXref ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/e6b93> ;
        gpml:database     "Pubmed" ;
        gpml:id           "27320729" .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/c4c53/Point/286bdf29084ea006b9ff877bbbe856f3>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/c4c53> ;
        gpml:graphRef     "a762f" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "220.13352255335934"^^xsd:double ;
        gpml:y            "618.6557792395638"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/State/e38e4>
        rdf:type            gpml:State ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:color          "0" ;
        gpml:fillColor      "ffffff" ;
        gpml:graphId        "e38e4" ;
        gpml:graphRef       "ff0fb" ;
        gpml:height         "15.0"^^xsd:double ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:relX           "1.0"^^xsd:double ;
        gpml:relY           "1.0"^^xsd:double ;
        gpml:shapeType      "Oval" ;
        gpml:stateOf        <http://rdf.wikipathways.org/Pathway/WP5103_r119170/DataNode/ff0fb> ;
        gpml:stateType      "Unknown" ;
        gpml:textlabel      "" ;
        gpml:width          "15.0"^^xsd:double ;
        gpml:zorder         "33087"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/a1db9>
        rdf:type                 gpml:GraphicalLine ;
        dcterms:isPartOf         <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:biopaxRef           "fcf" , "d72" ;
        gpml:color               "ff0000" ;
        gpml:connectorType       "Elbow" ;
        gpml:graphId             "a1db9" ;
        gpml:hasPoint            <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/a1db9/Point/57b16759870b55cb4dda2db1aa040508> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/a1db9/Point/d5f76d66e7b3d33af8e305b841f558c8> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/a1db9/Point/51a9f235e8273c54696656dd3113328> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/a1db9/Point/a387153ecbb09e1e1be7cebb7e730bb5> ;
        gpml:hasPublicationXref  <https://identifiers.org/pubmed/28476236> , <https://identifiers.org/pubmed/29989768> ;
        gpml:lineStyle           "Solid" ;
        gpml:lineThickness       "1.0"^^xsd:double ;
        gpml:zorder              "32787"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/a99e0/Point/a4350e27909f448c9c4d7ac14ce64985>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/a99e0> ;
        gpml:graphRef     "d6538" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "579.0150825829472"^^xsd:double ;
        gpml:y            "225.7451593432695"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/a7c8e/Point/5400321cc0a77118071bc3d54f1dc570>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/a7c8e> ;
        gpml:graphRef     "b0da8" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "220.13352255335928"^^xsd:double ;
        gpml:y            "364.53316156634435"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/de018>
        rdf:type                 gpml:GraphicalLine ;
        dcterms:isPartOf         <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:biopaxRef           "d58" ;
        gpml:color               "0" ;
        gpml:connectorType       "Straight" ;
        gpml:graphId             "de018" ;
        gpml:hasPoint            <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/de018/Point/d8d80f5acbf11e6a8ea6d2dbf4a4ee2c> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/de018/Point/5f24139ac797977fa701c963bb38cd71> ;
        gpml:hasPublicationXref  <https://identifiers.org/pubmed/21639948> ;
        gpml:lineStyle           "Solid" ;
        gpml:lineThickness       "1.0"^^xsd:double ;
        gpml:zorder              "33056"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/id2699c0dc/Point/53b07c85dfa2d58118444c5b51c8c0d3>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/id2699c0dc> ;
        gpml:graphRef     "a51ed" ;
        gpml:relX         "1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "633.2626198963845"^^xsd:double ;
        gpml:y            "577.1992040844311"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/dea16/Point/bf59eecfe5956b2eda2b525cb8a05617>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/dea16> ;
        gpml:graphRef     "df33d" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "870.2545825829528"^^xsd:double ;
        gpml:y            "564.3216088443393"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/bf07c/Point/66eea507f23830174f123e4050bddd99>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/bf07c> ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "221.21662499999996"^^xsd:double ;
        gpml:y            "81.964"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/deba7/Point/9f9730260fa59eee9f604777be316b27>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/deba7> ;
        gpml:graphRef     "d7512" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "361.3943397270418"^^xsd:double ;
        gpml:y            "919.839688844668"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/ad194>
        rdf:type                 gpml:GraphicalLine ;
        dcterms:isPartOf         <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:biopaxRef           "ec8" ;
        gpml:color               "0" ;
        gpml:connectorType       "Straight" ;
        gpml:graphId             "ad194" ;
        gpml:hasPoint            <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/ad194/Point/47892db9c36e660fc38bd4f9bdb1a266> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/ad194/Point/8ca3ff53bd86da17111fc88ef0ec3507> ;
        gpml:hasPublicationXref  <https://identifiers.org/pubmed/32153505> ;
        gpml:lineStyle           "Solid" ;
        gpml:lineThickness       "1.0"^^xsd:double ;
        gpml:zorder              "32786"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/DataNode/ec575>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Group/e2f4a> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:align           "Center" ;
        gpml:centerX         "301.64004469889846"^^xsd:double ;
        gpml:centerY         "989.3920111499141"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "ec575" ;
        gpml:groupRef        "e2f4a" ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "LMNB1" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "90.0"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000113368" ;
        gpml:zorder          "33058"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Group/a762f>
        rdf:type          gpml:Group ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:graphId      "a762f" ;
        gpml:groupId      "a762f" ;
        gpml:style        "Complex" .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Label/ffc08>
        rdf:type             gpml:Label ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:align           "Center" ;
        gpml:centerX         "458.0113763333112"^^xsd:double ;
        gpml:centerY         "320.76799567713556"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "ffc08" ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:href            "" ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "None" ;
        gpml:textlabel       "non-matured Lamin A" ;
        gpml:valign          "Middle" ;
        gpml:width           "154.21479646410256"^^xsd:double ;
        gpml:zorder          "33068"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/DataNode/c7166>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Group/b0da8> ;
        gpml:align           "Center" ;
        gpml:centerX         "220.13352255335928"^^xsd:double ;
        gpml:centerY         "389.0331615663443"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "c7166" ;
        gpml:groupRef        "b0da8" ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "Prelamin-A/C" ;
        gpml:type            "Protein" ;
        gpml:valign          "Middle" ;
        gpml:width           "90.0"^^xsd:double ;
        gpml:xrefDataSource  "UniProtKB" ;
        gpml:xrefId          "P02545" ;
        gpml:zorder          "33069"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/deba7/Point/57e8ca90e3b7f87577687536fb84f407>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/deba7> ;
        gpml:graphRef     "ec7b0" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "301.64004469889846"^^xsd:double ;
        gpml:y            "886.3751881821663"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/id750caaa3/Point/1797fdd1848738bed129019640e6ae74>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/id750caaa3> ;
        gpml:graphRef     "ebb99" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "588.2626198963845"^^xsd:double ;
        gpml:y            "504.93825824041596"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/DataNode/aec98>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:align           "Center" ;
        gpml:centerX         "363.62816970558765"^^xsd:double ;
        gpml:centerY         "455.9013127404641"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "aec98" ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "FNTA" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "90.0"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000168522" ;
        gpml:zorder          "33074"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/a14a3/Point/9f8907a1555355b335444189567271b2>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/a14a3> ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "92.04066286836853"^^xsd:double ;
        gpml:y            "109.023"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/DataNode/d1975>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Group/e2c06> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:align           "Center" ;
        gpml:centerX         "220.13352255335928"^^xsd:double ;
        gpml:centerY         "505.358960351958"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "d1975" ;
        gpml:groupRef        "e2c06" ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "Prelamin-A/C" ;
        gpml:type            "Protein" ;
        gpml:valign          "Middle" ;
        gpml:width           "90.0"^^xsd:double ;
        gpml:xrefDataSource  "UniProtKB" ;
        gpml:xrefId          "P02545" ;
        gpml:zorder          "33079"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/b5342/Point/d48832eea947bb479e6158ed415db27b>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/b5342> ;
        gpml:graphRef     "f0473" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "1121.5877065374646"^^xsd:double ;
        gpml:y            "622.6772189135779"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/b8dbb>
        rdf:type                 gpml:GraphicalLine ;
        dcterms:isPartOf         <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:biopaxRef           "d72" ;
        gpml:color               "ff0000" ;
        gpml:connectorType       "Elbow" ;
        gpml:graphId             "b8dbb" ;
        gpml:hasPoint            <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/b8dbb/Point/7152a79482257e21237e8d61557e9b30> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/b8dbb/Point/2e5cd9a7156e1e6a79a03f17e9b7142d> ;
        gpml:hasPublicationXref  <https://identifiers.org/pubmed/29989768> ;
        gpml:lineStyle           "Solid" ;
        gpml:lineThickness       "1.0"^^xsd:double ;
        gpml:zorder              "33062"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/ba127>
        rdf:type                 gpml:GraphicalLine ;
        dcterms:isPartOf         <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:biopaxRef           "d72" , "fcf" ;
        gpml:color               "ff0000" ;
        gpml:connectorType       "Elbow" ;
        gpml:graphId             "ba127" ;
        gpml:hasPoint            <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/ba127/Point/ba25feaa2387d0f3494dfcae9eb6e61c> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/ba127/Point/ebf9ad7d6116a6a33d8fdfd3e7e36035> ;
        gpml:hasPublicationXref  <https://identifiers.org/pubmed/28476236> , <https://identifiers.org/pubmed/29989768> ;
        gpml:lineStyle           "Solid" ;
        gpml:lineThickness       "1.0"^^xsd:double ;
        gpml:zorder              "32783"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/a5ff1/Point/aa96088af772e47dd775523e4a46249b>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/a5ff1> ;
        gpml:graphRef     "aec98" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "318.62816970558765"^^xsd:double ;
        gpml:y            "455.9013127404641"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/DataNode/e8061>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Group/f219c> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:align           "Center" ;
        gpml:centerX         "1009.8240136268856"^^xsd:double ;
        gpml:centerY         "944.390832850731"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "e8061" ;
        gpml:groupRef        "f219c" ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "SMAD3" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "90.0"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000166949" ;
        gpml:zorder          "33092"^^xsd:long .

<https://identifiers.org/pubmed/29989768>
        rdf:type          gpml:PublicationXref ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/b8dbb> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/a1db9> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/e87cd> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/dd30c> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/cb3ec> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/f5767> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/dea16> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/a507b> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/cb43d> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/ba127> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/ecbee> ;
        gpml:database     "Pubmed" ;
        gpml:id           "29989768" .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Label/d71b4>
        rdf:type             gpml:Label ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:align           "Center" ;
        gpml:centerX         "150.3807087696028"^^xsd:double ;
        gpml:centerY         "206.2272560739182"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "d71b4" ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:href            "" ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "None" ;
        gpml:textlabel       "Gene/protein" ;
        gpml:valign          "Middle" ;
        gpml:width           "70.72181859618681"^^xsd:double ;
        gpml:zorder          "28672"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Label/bddc5>
        rdf:type             gpml:Label ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:align           "Center" ;
        gpml:centerX         "561.3402117836355"^^xsd:double ;
        gpml:centerY         "777.8742229728698"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "bddc5" ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:href            "" ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "None" ;
        gpml:textlabel       "DNA damage repair" ;
        gpml:valign          "Middle" ;
        gpml:width           "119.87126865671641"^^xsd:double ;
        gpml:zorder          "28672"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/DataNode/e0bcb>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:align           "Center" ;
        gpml:centerX         "734.8600303517707"^^xsd:double ;
        gpml:centerY         "675.0261901268501"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "e0bcb" ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "PARP1" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "90.0"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000143799" ;
        gpml:zorder          "32768"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/b3ecb/Point/c1fcedeff16048c020bf6dddfa66d0e8>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/b3ecb> ;
        gpml:graphRef     "aa473" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "220.13352255336065"^^xsd:double ;
        gpml:y            "728.1392493777371"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/iddaec0a84>
        rdf:type            gpml:GraphicalLine ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:color          "0" ;
        gpml:connectorType  "Elbow" ;
        gpml:graphId        "iddaec0a84" ;
        gpml:hasPoint       <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/iddaec0a84/Point/b32473ce3a15e4b373abaf33051c2f17> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/iddaec0a84/Point/5297978759bbe30b2b9df7a0030a0524> ;
        gpml:lineStyle      "Solid" ;
        gpml:lineThickness  "1.0"^^xsd:double ;
        gpml:zorder         "12288"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/e88d6/Point/f512247ccea238e9dde9cac0b131f28e>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/e88d6> ;
        gpml:graphRef     "fcbf9" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "595.0412415321109"^^xsd:double ;
        gpml:y            "932.3396888446678"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/dd30c>
        rdf:type                 gpml:GraphicalLine ;
        dcterms:isPartOf         <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:biopaxRef           "d72" , "fcf" ;
        gpml:color               "ff0000" ;
        gpml:connectorType       "Straight" ;
        gpml:graphId             "dd30c" ;
        gpml:hasPoint            <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/dd30c/Point/ac156fcf6d52b7a479347e1aefcd5581> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/dd30c/Point/409f5a69e6a521d5a3b266b4a5af7880> ;
        gpml:hasPublicationXref  <https://identifiers.org/pubmed/28476236> , <https://identifiers.org/pubmed/29989768> ;
        gpml:lineStyle           "Solid" ;
        gpml:lineThickness       "1.0"^^xsd:double ;
        gpml:zorder              "32788"^^xsd:long .

<https://identifiers.org/pubmed/7796919>
        rdf:type          gpml:PublicationXref ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/id750caaa3> ;
        gpml:database     "Pubmed" ;
        gpml:id           "7796919" .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Shape/c3413>
        rdf:type             gpml:shape ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:align           "Center" ;
        gpml:centerX         "67.80402985074642"^^xsd:double ;
        gpml:centerY         "202.3039738805968"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "c3413" ;
        gpml:height          "21.77026119402891"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shape           "0.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "x" ;
        gpml:valign          "Middle" ;
        gpml:width           "80.32429104477606"^^xsd:double ;
        gpml:zorder          "33190"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/e2019/Point/3acd59a38467fc8ef55d3631d24f6579>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/e2019> ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "220.50000000000003"^^xsd:double ;
        gpml:y            "114.319"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/DataNode/ebb99>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:align           "Center" ;
        gpml:centerX         "588.2626198963845"^^xsd:double ;
        gpml:centerY         "517.438258240416"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "ebb99" ;
        gpml:height          "25.000000000000114"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "Insulin" ;
        gpml:type            "Protein" ;
        gpml:valign          "Middle" ;
        gpml:width           "90.0"^^xsd:double ;
        gpml:xrefDataSource  "UniProtKB" ;
        gpml:xrefId          "A6XGL2" ;
        gpml:zorder          "32820"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/e5979/Point/5999a36205813a6f52935867a22375a4>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/e5979> ;
        gpml:graphRef     "e2665" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "318.62816970558765"^^xsd:double ;
        gpml:y            "815.508908317835"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/c4c53>
        rdf:type                 gpml:Interaction ;
        dcterms:isPartOf         <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:biopaxRef           "d01" ;
        gpml:color               "0" ;
        gpml:connectorType       "Straight" ;
        gpml:graphId             "c4c53" ;
        gpml:hasAnchor           <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/c4c53/Anchor/c6b9d> ;
        gpml:hasPoint            <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/c4c53/Point/69af5a964a34b796364d4121fc80151e> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/c4c53/Point/286bdf29084ea006b9ff877bbbe856f3> ;
        gpml:hasPublicationXref  <https://identifiers.org/pubmed/17660942> ;
        gpml:lineStyle           "Solid" ;
        gpml:lineThickness       "1.0"^^xsd:double ;
        gpml:zorder              "33054"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Group/b0da8>
        rdf:type          gpml:Group ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:graphId      "b0da8" ;
        gpml:groupId      "b0da8" ;
        gpml:style        "Complex" .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/DataNode/fdf9f>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Group/a762f> ;
        gpml:align           "Center" ;
        gpml:centerX         "220.13352255336207"^^xsd:double ;
        gpml:centerY         "643.1557792395637"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "fdf9f" ;
        gpml:groupRef        "a762f" ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "Prelamin-A/C" ;
        gpml:type            "Protein" ;
        gpml:valign          "Middle" ;
        gpml:width           "90.83837121212142"^^xsd:double ;
        gpml:xrefDataSource  "UniProtKB" ;
        gpml:xrefId          "P02545" ;
        gpml:zorder          "33081"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/id2311ce5b/Point/e93c6510633a9fecde87080ef20ec4c2>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/id2311ce5b> ;
        gpml:graphRef     "b2571" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "1009.8240136268855"^^xsd:double ;
        gpml:y            "841.4005343432679"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/ba127/Point/ebf9ad7d6116a6a33d8fdfd3e7e36035>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/ba127> ;
        gpml:graphRef     "e440d" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "692.573832582949"^^xsd:double ;
        gpml:y            "254.2451593432695"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/b5342>
        rdf:type                 gpml:GraphicalLine ;
        dcterms:isPartOf         <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:biopaxRef           "c20" , "d31" ;
        gpml:color               "0" ;
        gpml:connectorType       "Straight" ;
        gpml:graphId             "b5342" ;
        gpml:hasPoint            <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/b5342/Point/3d7ba9a912ae2f5630210ce51e069e04> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/b5342/Point/d48832eea947bb479e6158ed415db27b> ;
        gpml:hasPublicationXref  <https://identifiers.org/pubmed/32439107> , <https://identifiers.org/pubmed/27437668> ;
        gpml:lineStyle           "Solid" ;
        gpml:lineThickness       "1.0"^^xsd:double ;
        gpml:zorder              "32775"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/ecbee/Point/54aa78206794b3bcbcb7c8e052acf1b0>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/ecbee> ;
        gpml:graphRef     "efb22" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "1190.3388325829412"^^xsd:double ;
        gpml:y            "254.2451593432695"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/id1eace11e/Point/1ed081588ff9b56e2381d90acbff3236>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/id1eace11e> ;
        gpml:graphRef     "f4495" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "475.01508258294723"^^xsd:double ;
        gpml:y            "225.7451593432695"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/DataNode/f626b>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:align           "Center" ;
        gpml:centerX         "900.015082582947"^^xsd:double ;
        gpml:centerY         "239.9951593432695"^^xsd:double ;
        gpml:color           "cc3300" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "f626b" ;
        gpml:height          "28.5"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "Marfan \nsyndrome" ;
        gpml:type            "Unknown" ;
        gpml:valign          "Middle" ;
        gpml:width           "90.0"^^xsd:double ;
        gpml:xrefDataSource  "Wikidata" ;
        gpml:xrefId          "Q208562" ;
        gpml:zorder          "32768"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Label/a1d7d>
        rdf:type             gpml:Label ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:align           "Center" ;
        gpml:centerX         "325.1352282361001"^^xsd:double ;
        gpml:centerY         "175.1543896081954"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "a1d7d" ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:href            "" ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "None" ;
        gpml:textlabel       "Binding" ;
        gpml:valign          "Middle" ;
        gpml:width           "90.0"^^xsd:double ;
        gpml:zorder          "28672"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/dd30c/Point/ac156fcf6d52b7a479347e1aefcd5581>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/dd30c> ;
        gpml:graphRef     "eb3f8" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "1262.7213325829373"^^xsd:double ;
        gpml:y            "254.2451593432695"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/bf07c/Point/9a11a5f75c0e95f15e73713b5b5ade72>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/bf07c> ;
        gpml:graphRef     "cb80e" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "280.1352282361001"^^xsd:double ;
        gpml:y            "81.96438789743581"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/bcab1/Point/8a6518d8d1eb2d223097b13c79a0d189>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/bcab1> ;
        gpml:graphRef     "d9f15" ;
        gpml:relX         "1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "1307.7213325829373"^^xsd:double ;
        gpml:y            "313.134188506874"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Label/d8c2b>
        rdf:type             gpml:Label ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:align           "Center" ;
        gpml:centerX         "64.06495350806594"^^xsd:double ;
        gpml:centerY         "135.92081369546312"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "d8c2b" ;
        gpml:height          "15.094004758680285"^^xsd:double ;
        gpml:href            "" ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "None" ;
        gpml:textlabel       "M" ;
        gpml:valign          "Middle" ;
        gpml:width           "17.585921862903895"^^xsd:double ;
        gpml:zorder          "33099"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/idc66823a3/Point/918f861f1c3347d20427d9a2c0367ccc>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/idc66823a3> ;
        gpml:graphRef     "e8fb3" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "840.1330544445436"^^xsd:double ;
        gpml:y            "181.0285874649378"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/e654c/Point/ee8ca04ab66111fe203738b9c4b40a08>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/e654c> ;
        gpml:graphRef     "a1d7d" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "280.1352282361001"^^xsd:double ;
        gpml:y            "175.1543896081954"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/dea16/Point/a9ae11b97d40ed5e22759c23f4edcfab>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/dea16> ;
        gpml:graphRef     "f626b" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "900.015082582947"^^xsd:double ;
        gpml:y            "254.2451593432695"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/abc5a>
        rdf:type                 gpml:Interaction ;
        dcterms:isPartOf         <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:biopaxRef           "d01" ;
        gpml:color               "0" ;
        gpml:connectorType       "Elbow" ;
        gpml:graphId             "abc5a" ;
        gpml:hasAnchor           <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/abc5a/Anchor/d0a52> ;
        gpml:hasPoint            <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/abc5a/Point/88cf3bbafe1c06a7e51e7d8be6f42a66> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/abc5a/Point/398abce50fb957bd1fe8b67cfbe1de98> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/abc5a/Point/c7154b6dffc0f2ea2c7d142691a09d90> ;
        gpml:hasPublicationXref  <https://identifiers.org/pubmed/17660942> ;
        gpml:lineStyle           "Solid" ;
        gpml:lineThickness       "1.0"^^xsd:double ;
        gpml:zorder              "33090"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Comment/8fa6ba8ead2ae3a877f73697c5e5bbc8>
        rdf:type          gpml:Comment ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170/DataNode/aaaed> ;
        gpml:commentText  "GIRK2" .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/bf102/Point/7bef0423abf60d65ebf7b3ab70991167>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/bf102> ;
        gpml:graphRef     "e8159" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "1.0"^^xsd:double ;
        gpml:x            "614.3121954560808"^^xsd:double ;
        gpml:y            "631.1444067062661"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/id2311ce5b/Point/6e0a8d43aa2518213fff16c96db46c6a>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/id2311ce5b> ;
        gpml:graphRef     "f219c" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "1009.8240136268855"^^xsd:double ;
        gpml:y            "894.890832850731"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/a5a0b/Point/45d31ed9a88a424a27c9ff702d35a73a>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/a5a0b> ;
        gpml:graphRef     "d7512" ;
        gpml:relX         "-1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "361.3943397270418"^^xsd:double ;
        gpml:y            "919.839688844668"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/b2689/Point/7009047e4f3eb7f38bc05f42c398f156>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/b2689> ;
        gpml:graphRef     "e8159" ;
        gpml:relX         "1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "662.7802411650356"^^xsd:double ;
        gpml:y            "618.6444067062661"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/DataNode/c9144>
        rdf:type             gpml:DataNode ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Group/b2571> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:align           "Center" ;
        gpml:centerX         "1009.8240136268856"^^xsd:double ;
        gpml:centerY         "816.9005343432679"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "c9144" ;
        gpml:groupRef        "b2571" ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "Rectangle" ;
        gpml:textlabel       "SMAD3" ;
        gpml:type            "GeneProduct" ;
        gpml:valign          "Middle" ;
        gpml:width           "90.0"^^xsd:double ;
        gpml:xrefDataSource  "Ensembl" ;
        gpml:xrefId          "ENSG00000166949" ;
        gpml:zorder          "32768"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/e88d6/Point/8aede580e571abbe2daeffe3b52bc571>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/e88d6> ;
        gpml:graphRef     "f3f7f" ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "-1.0"^^xsd:double ;
        gpml:x            "595.0412415321124"^^xsd:double ;
        gpml:y            "1001.2022321525121"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/dd30c/Point/409f5a69e6a521d5a3b266b4a5af7880>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/dd30c> ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "1262.7213325829373"^^xsd:double ;
        gpml:y            "300.634188506874"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Label/b5337>
        rdf:type             gpml:Label ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:align           "Center" ;
        gpml:centerX         "220.12340527162095"^^xsd:double ;
        gpml:centerY         "886.5993796033185"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "b5337" ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:href            "" ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "None" ;
        gpml:textlabel       "M" ;
        gpml:valign          "Middle" ;
        gpml:width           "90.0"^^xsd:double ;
        gpml:zorder          "33088"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/a507b/Point/f18096f0c077e8b5df2d44493b5a552>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/a507b> ;
        gpml:relX         "0.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "1010.5444575829478"^^xsd:double ;
        gpml:y            "372.4235963041934"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/a7c8e>
        rdf:type                 gpml:Interaction ;
        dcterms:isPartOf         <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:biopaxRef           "d01" , "f21" ;
        gpml:color               "0" ;
        gpml:connectorType       "Straight" ;
        gpml:graphId             "a7c8e" ;
        gpml:hasPoint            <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/a7c8e/Point/5400321cc0a77118071bc3d54f1dc570> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/Interaction/a7c8e/Point/499986f8c27b61f118c7c49a51c75dfe> ;
        gpml:hasPublicationXref  <https://identifiers.org/pubmed/19956441> , <https://identifiers.org/pubmed/17660942> ;
        gpml:lineStyle           "Solid" ;
        gpml:lineThickness       "1.0"^^xsd:double ;
        gpml:zorder              "33049"^^xsd:long .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/c363f/Point/c8bac20697a75afd636f353874987899>
        rdf:type          gpml:Point ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP5103_r119170> , <http://rdf.wikipathways.org/Pathway/WP5103_r119170/GraphicalLine/c363f> ;
        gpml:graphRef     "f219c" ;
        gpml:relX         "1.0"^^xsd:double ;
        gpml:relY         "0.0"^^xsd:double ;
        gpml:x            "1066.8240136268855"^^xsd:double ;
        gpml:y            "944.390832850731"^^xsd:double .

<http://rdf.wikipathways.org/Pathway/WP5103_r119170/Label/e228e>
        rdf:type             gpml:Label ;
        dcterms:isPartOf     <http://rdf.wikipathways.org/Pathway/WP5103_r119170> ;
        gpml:align           "Center" ;
        gpml:centerX         "325.13522823610015"^^xsd:double ;
        gpml:centerY         "241.48824787082964"^^xsd:double ;
        gpml:color           "0" ;
        gpml:fillColor       "ffffff" ;
        gpml:fontDecoration  "Normal" ;
        gpml:fontName        "Arial" ;
        gpml:fontSize        "12.0"^^xsd:double ;
        gpml:fontStrikethru  "Normal" ;
        gpml:fontStyle       "Normal" ;
        gpml:fontWeight      "Normal" ;
        gpml:graphId         "e228e" ;
        gpml:height          "25.0"^^xsd:double ;
        gpml:href            "" ;
        gpml:lineStyle       "Solid" ;
        gpml:lineThickness   "1.0"^^xsd:double ;
        gpml:shapeType       "None" ;
        gpml:textlabel       "Transcription" ;
        gpml:valign          "Middle" ;
        gpml:width           "90.0"^^xsd:double ;
        gpml:zorder          "28672"^^xsd:long .
