@prefix biopax:  <http://www.biopax.org/release/biopax-level3.owl#> .
@prefix cito:    <http://purl.org/spar/cito/> .
@prefix dc:      <http://purl.org/dc/elements/1.1/> .
@prefix dcterms: <http://purl.org/dc/terms/> .
@prefix foaf:    <http://xmlns.com/foaf/0.1/> .
@prefix freq:    <http://purl.org/cld/freq/> .
@prefix gpml:    <http://vocabularies.wikipathways.org/gpml#> .
@prefix obo:     <http://purl.obolibrary.org/obo/> .
@prefix owl:     <http://www.w3.org/2002/07/owl#> .
@prefix pav:     <http://purl.org/pav/> .
@prefix prov:    <http://www.w3.org/ns/prov#> .
@prefix rdf:     <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix rdfs:    <http://www.w3.org/2000/01/rdf-schema#> .
@prefix skos:    <http://www.w3.org/2004/02/skos/core#> .
@prefix void:    <http://rdfs.org/ns/void#> .
@prefix wp:      <http://vocabularies.wikipathways.org/wp#> .
@prefix wprdf:   <http://rdf.wikipathways.org/> .
@prefix xsd:     <http://www.w3.org/2001/XMLSchema#> .

<https://identifiers.org/hmdb/HMDB0000027>
        rdf:type            wp:Metabolite , wp:DataNode ;
        rdfs:label          "Tetrahydrobiopterin" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/FNKQXYHWGSIFBK-RPDRRWSUSA-N> ;
        dc:identifier       <https://identifiers.org/hmdb/HMDB0000027> ;
        dc:source           "HMDB" ;
        dcterms:identifier  "HMDB0000027" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2436_r139680> , <http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/b1b2f> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:59560> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/40270> ;
        wp:bdbHmdb          <https://identifiers.org/hmdb/HMDB0000027> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/FNKQXYHWGSIFBK-RPDRRWSUSA-N> ;
        wp:bdbKeggCompound  <https://identifiers.org/kegg.compound/C00272> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID44257> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q419808> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2436_r139680/DataNode/ef729> ;
        foaf:page           <http://www.hmdb.ca/metabolites/HMDB0000027> .

<https://identifiers.org/hmdb/HMDB0005784>
        rdf:type            wp:DataNode , wp:Metabolite ;
        rdfs:label          "DOPET" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/JUUBCHWRXWPFFH-UHFFFAOYSA-N> ;
        dc:identifier       <https://identifiers.org/hmdb/HMDB0005784> ;
        dc:source           "HMDB" ;
        dcterms:identifier  "HMDB0005784" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2436_r139680> , <http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/bc675> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:68889> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/74680> ;
        wp:bdbHmdb          <https://identifiers.org/hmdb/HMDB0005784> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/JUUBCHWRXWPFFH-UHFFFAOYSA-N> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID82755> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q744577> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2436_r139680/DataNode/de5a4> ;
        foaf:page           <http://www.hmdb.ca/metabolites/HMDB0005784> .

<https://identifiers.org/hmdb/HMDB0004058>
        rdf:type            wp:DataNode , wp:Metabolite ;
        rdfs:label          "5,6-Dihydroxyindole" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/SGNZYJXNUURYCH-UHFFFAOYSA-N> ;
        dc:identifier       <https://identifiers.org/hmdb/HMDB0004058> ;
        dc:source           "HMDB" ;
        dcterms:identifier  "HMDB0004058" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2436_r139680> , <http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/bcf1b> , <http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/b8a34> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:27404> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/102690> ;
        wp:bdbHmdb          <https://identifiers.org/hmdb/HMDB0004058> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/SGNZYJXNUURYCH-UHFFFAOYSA-N> ;
        wp:bdbKeggCompound  <https://identifiers.org/kegg.compound/C05578> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID114683> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q9207472> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2436_r139680/DataNode/c3ef3> ;
        foaf:page           <http://www.hmdb.ca/metabolites/HMDB0004058> .

<https://identifiers.org/hmdb/HMDB0002281>
        rdf:type            wp:Metabolite , wp:DataNode ;
        rdfs:label          "4a-Hydroxytetrahydrobiopterin" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/KJKIEFUPAPPGBC-XXKOCQOQSA-N> ;
        dc:identifier       <https://identifiers.org/hmdb/HMDB0002281> ;
        dc:source           "HMDB" ;
        dcterms:identifier  "HMDB0002281" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2436_r139680> , <http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/b1b2f> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:15642> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/30792101> ;
        wp:bdbHmdb          <https://identifiers.org/hmdb/HMDB0002281> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/KJKIEFUPAPPGBC-XXKOCQOQSA-N> ;
        wp:bdbKeggCompound  <https://identifiers.org/kegg.compound/C15522> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID135476770> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q24063330> , <http://www.wikidata.org/entity/Q74417390> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2436_r139680/DataNode/eec27> ;
        foaf:page           <http://www.hmdb.ca/metabolites/HMDB0002281> .

<https://identifiers.org/ncbigene/5568>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "PRKACG" ;
        dc:identifier       <https://identifiers.org/ncbigene/5568> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "5568" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2436_r139680> , <http://rdf.wikipathways.org/Pathway/WP2436_r139680/Complex/af0ea> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000165059> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/5568> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/PRKACG> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/P22612> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2436_r139680/DataNode/fec1d> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P22612> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/5568> .

<https://identifiers.org/ncbigene/1644>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "DDC" ;
        dc:identifier       <https://identifiers.org/ncbigene/1644> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "1644" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2436_r139680/Complex/f0966> , <https://identifiers.org/wikipathways/WP2436_r139680> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000132437> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/1644> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/DDC> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/F8WER1> , <https://identifiers.org/uniprot/A0A0S2Z3N4> , <https://identifiers.org/uniprot/A0A087WV24> , <https://identifiers.org/uniprot/A0A087WU57> , <https://identifiers.org/uniprot/P20711> , <https://identifiers.org/uniprot/H7BZF7> , <https://identifiers.org/uniprot/C9JMP0> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2436_r139680/DataNode/b496b> , <http://rdf.wikipathways.org/Pathway/WP2436_r139680/DataNode/b6fce> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P20711> , <http://purl.uniprot.org/uniprot/C9JMP0> , <http://purl.uniprot.org/uniprot/H7BZF7> , <http://purl.uniprot.org/uniprot/A0A087WU57> , <http://purl.uniprot.org/uniprot/A0A087WV24> , <http://purl.uniprot.org/uniprot/A0A0S2Z3N4> , <http://purl.uniprot.org/uniprot/F8WER1> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/1644> .

<https://identifiers.org/pubchem.compound/46173450>
        rdf:type            wp:DataNode , wp:Metabolite ;
        rdfs:label          "ICQA" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/FXURFKFOPCZEKG-UHFFFAOYSA-N> ;
        dc:identifier       <https://identifiers.org/pubchem.compound/46173450> ;
        dc:source           "PubChem-compound" ;
        dcterms:identifier  "46173450" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2436_r139680> , <http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/aff4f> , <http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/b1b84> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:177869> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/FXURFKFOPCZEKG-UHFFFAOYSA-M> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID46173450> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q33625489> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2436_r139680/DataNode/ea6d9> ;
        foaf:page           <http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=46173450> .

<http://rdf.wikipathways.org/Pathway/WP2436_r139680/ComplexBinding/cfdf6>
        rdf:type          wp:ComplexBinding , wp:Binding , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2436_r139680> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2436_r139680/Group/cfdf6> ;
        wp:participants   <https://identifiers.org/ncbigene/5516> , <https://identifiers.org/ncbigene/5515> , <http://rdf.wikipathways.org/Pathway/WP2436_r139680/Complex/cfdf6> .

<http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/e13b9>
        rdf:type          wp:Catalysis , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2436_r139680> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2436_r139680/Interaction/e13b9> ;
        wp:participants   <http://rdf.wikipathways.org/Pathway/WP2436_r139680/Complex/bbcc1> , <http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/b1b2f> ;
        wp:source         <http://rdf.wikipathways.org/Pathway/WP2436_r139680/Complex/bbcc1> ;
        wp:target         <http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/b1b2f> .

<https://identifiers.org/pmc/PMC12448840>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed Central" ;
        dcterms:identifier  "PMC12448840" ;
        cito:cites          <https://identifiers.org/wikipathways/WP2436> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/PMC12448840> .

<http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/b8a34>
        rdf:type          wp:Conversion , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2436_r139680> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2436_r139680/Interaction/b8a34> ;
        wp:participants   <https://identifiers.org/wikidata/Q1981297> , <https://identifiers.org/hmdb/HMDB0004058> ;
        wp:source         <https://identifiers.org/hmdb/HMDB0004058> ;
        wp:target         <https://identifiers.org/wikidata/Q1981297> .

<https://identifiers.org/ncbigene/4128>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "MAOA" ;
        dc:identifier       <https://identifiers.org/ncbigene/4128> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "4128" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2436_r139680/Complex/c4d5f> , <https://identifiers.org/wikipathways/WP2436_r139680> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000189221> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/4128> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/MAOA> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q53YE7> , <https://identifiers.org/uniprot/P21397> , <https://identifiers.org/uniprot/A0A8I5KP93> , <https://identifiers.org/uniprot/A0A8I5KUC3> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2436_r139680/DataNode/ae37d> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P21397> , <http://purl.uniprot.org/uniprot/A0A8I5KUC3> , <http://purl.uniprot.org/uniprot/Q53YE7> , <http://purl.uniprot.org/uniprot/A0A8I5KP93> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/4128> .

<http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/e8bab>
        rdf:type          wp:Catalysis , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2436_r139680> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2436_r139680/Interaction/e8bab> ;
        wp:participants   <http://rdf.wikipathways.org/Pathway/WP2436_r139680/Complex/f0e09> , <http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/ded6b> ;
        wp:source         <http://rdf.wikipathways.org/Pathway/WP2436_r139680/Complex/f0e09> ;
        wp:target         <http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/ded6b> .

<http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/a19ed>
        rdf:type          wp:Conversion , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2436_r139680> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2436_r139680/Interaction/a19ed> ;
        wp:participants   <https://identifiers.org/hmdb/HMDB0000022> , <https://identifiers.org/hmdb/HMDB0000073> ;
        wp:source         <https://identifiers.org/hmdb/HMDB0000073> ;
        wp:target         <https://identifiers.org/hmdb/HMDB0000022> .

<https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=png&pwTitle=Pathway:WP2436&oldid=139680>
        rdf:type        foaf:Image ;
        dcterms:format  "image/png" .

<https://identifiers.org/ncbigene/7054>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "TH" ;
        dc:identifier       <https://identifiers.org/ncbigene/7054> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "7054" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2436_r139680> , <http://rdf.wikipathways.org/Pathway/WP2436_r139680/Complex/bbcc1> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000180176> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/7054> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/TH> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/P07101> , <https://identifiers.org/uniprot/E7EQI0> , <https://identifiers.org/uniprot/H0Y677> , <https://identifiers.org/uniprot/H0Y670> , <https://identifiers.org/uniprot/F8W8M5> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2436_r139680/DataNode/c6b80> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/E7EQI0> , <http://purl.uniprot.org/uniprot/F8W8M5> , <http://purl.uniprot.org/uniprot/H0Y670> , <http://purl.uniprot.org/uniprot/P07101> , <http://purl.uniprot.org/uniprot/H0Y677> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/7054> .

<https://identifiers.org/hmdb/HMDB0001253>
        rdf:type            wp:DataNode , wp:Metabolite ;
        rdfs:label          "DHICA" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/YFTGOBNOJKXZJC-UHFFFAOYSA-N> ;
        dc:identifier       <https://identifiers.org/hmdb/HMDB0001253> ;
        dc:source           "HMDB" ;
        dcterms:identifier  "HMDB0001253" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2436_r139680> , <http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/b1b84> , <http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/fb2de> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:2003> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/106648> ;
        wp:bdbHmdb          <https://identifiers.org/hmdb/HMDB0001253> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/YFTGOBNOJKXZJC-UHFFFAOYSA-N> ;
        wp:bdbKeggCompound  <https://identifiers.org/kegg.compound/C04185> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID119405> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q5205021> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2436_r139680/DataNode/ae573> ;
        foaf:page           <http://www.hmdb.ca/metabolites/HMDB0001253> .

<http://rdf.wikipathways.org/Pathway/WP2436_r139680/ComplexBinding/f0e09>
        rdf:type          wp:ComplexBinding , wp:Binding , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2436_r139680> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2436_r139680/Group/f0e09> ;
        wp:participants   <https://identifiers.org/hmdb/HMDB0001248> , <https://identifiers.org/ncbigene/4129> , <http://rdf.wikipathways.org/Pathway/WP2436_r139680/Complex/f0e09> .

<http://rdf.wikipathways.org/Pathway/WP2436_r139680/Complex/f0966>
        rdf:type          wp:Complex , wp:DataNode ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/ae7ba> , <https://identifiers.org/wikipathways/WP2436_r139680> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2436_r139680/Group/f0966> ;
        wp:participants   <https://identifiers.org/ncbigene/1644> .

<http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/cf41a>
        rdf:type          wp:Conversion , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2436_r139680> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2436_r139680/Interaction/cf41a> ;
        wp:participants   <https://identifiers.org/hmdb/HMDB0012992> , <https://identifiers.org/hmdb/HMDB0012219> ;
        wp:source         <https://identifiers.org/hmdb/HMDB0012219> ;
        wp:target         <https://identifiers.org/hmdb/HMDB0012992> .

<https://identifiers.org/ncbigene/5567>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "PRKACB" ;
        dc:identifier       <https://identifiers.org/ncbigene/5567> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "5567" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2436_r139680/Complex/af0ea> , <https://identifiers.org/wikipathways/WP2436_r139680> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000142875> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/5567> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/PRKACB> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/P22694> , <https://identifiers.org/uniprot/B1APF9> , <https://identifiers.org/uniprot/B1APG2> , <https://identifiers.org/uniprot/B1APF7> , <https://identifiers.org/uniprot/B1APG3> , <https://identifiers.org/uniprot/A0A087WVC4> , <https://identifiers.org/uniprot/B1APF8> , <https://identifiers.org/uniprot/B1APG0> , <https://identifiers.org/uniprot/B2RB89> , <https://identifiers.org/uniprot/B1APG1> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2436_r139680/DataNode/cd881> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/B1APG2> , <http://purl.uniprot.org/uniprot/B2RB89> , <http://purl.uniprot.org/uniprot/B1APG0> , <http://purl.uniprot.org/uniprot/B1APF8> , <http://purl.uniprot.org/uniprot/B1APG1> , <http://purl.uniprot.org/uniprot/B1APF9> , <http://purl.uniprot.org/uniprot/P22694> , <http://purl.uniprot.org/uniprot/B1APG3> , <http://purl.uniprot.org/uniprot/A0A087WVC4> , <http://purl.uniprot.org/uniprot/B1APF7> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/5567> .

<http://rdf.wikipathways.org/Pathway/WP2436_r139680/Complex/c4d5f>
        rdf:type          wp:Complex , wp:DataNode ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/a07f7> , <http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/efc07> , <http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/af572> , <https://identifiers.org/wikipathways/WP2436_r139680> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2436_r139680/Group/c4d5f> ;
        wp:participants   <https://identifiers.org/ncbigene/4128> , <https://identifiers.org/hmdb/HMDB0001248> .

<https://identifiers.org/ncbigene/1728>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "NQO1" ;
        dc:identifier       <https://identifiers.org/ncbigene/1728> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "1728" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2436_r139680> , <http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/e9793> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000181019> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/1728> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/NQO1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/H3BRK3> , <https://identifiers.org/uniprot/H3BNV2> , <https://identifiers.org/uniprot/P15559> , <https://identifiers.org/uniprot/B4DLR8> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2436_r139680/DataNode/c3b60> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/H3BNV2> , <http://purl.uniprot.org/uniprot/H3BRK3> , <http://purl.uniprot.org/uniprot/P15559> , <http://purl.uniprot.org/uniprot/B4DLR8> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/1728> .

<http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/ded6b>
        rdf:type          wp:Conversion , wp:Interaction , wp:DirectedInteraction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2436_r139680> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2436_r139680/Interaction/ded6b> , <http://rdf.wikipathways.org/Pathway/WP2436_r139680/Interaction/f8638> , <http://rdf.wikipathways.org/Pathway/WP2436_r139680/Interaction/f2128> , <http://rdf.wikipathways.org/Pathway/WP2436_r139680/Interaction/a95be> ;
        wp:participants   <https://identifiers.org/hmdb/HMDB0001377> , <https://identifiers.org/hmdb/HMDB0003791> , <https://identifiers.org/hmdb/HMDB0000073> , <https://identifiers.org/hmdb/HMDB0003125> , <https://identifiers.org/hmdb/HMDB0002111> ;
        wp:source         <https://identifiers.org/hmdb/HMDB0002111> , <https://identifiers.org/hmdb/HMDB0000073> , <https://identifiers.org/hmdb/HMDB0001377> ;
        wp:target         <https://identifiers.org/hmdb/HMDB0003791> , <https://identifiers.org/hmdb/HMDB0003125> .

<http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/b1b2f>
        rdf:type          wp:Conversion , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2436_r139680> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2436_r139680/Interaction/ab0f3> , <http://rdf.wikipathways.org/Pathway/WP2436_r139680/Interaction/b1b2f> , <http://rdf.wikipathways.org/Pathway/WP2436_r139680/Interaction/dcd0d> ;
        wp:participants   <https://identifiers.org/hmdb/HMDB0002281> , <https://identifiers.org/hmdb/HMDB0000027> , <https://identifiers.org/hmdb/HMDB0000158> , <https://identifiers.org/hmdb/HMDB0000181> ;
        wp:source         <https://identifiers.org/hmdb/HMDB0000158> , <https://identifiers.org/hmdb/HMDB0000027> ;
        wp:target         <https://identifiers.org/hmdb/HMDB0000181> , <https://identifiers.org/hmdb/HMDB0002281> .

<https://identifiers.org/hmdb/HMDB0000118>
        rdf:type            wp:Metabolite , wp:DataNode ;
        rdfs:label          "Homovanillic acid" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/QRMZSPFSDQBLIX-UHFFFAOYSA-N> ;
        dc:identifier       <https://identifiers.org/hmdb/HMDB0000118> ;
        dc:source           "HMDB" ;
        dcterms:identifier  "HMDB0000118" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/d29f2> , <https://identifiers.org/wikipathways/WP2436_r139680> , <http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/cfd80> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:545959> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/1675> ;
        wp:bdbHmdb          <https://identifiers.org/hmdb/HMDB0000118> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/QRMZSPFSDQBLIX-UHFFFAOYSA-N> ;
        wp:bdbKeggCompound  <https://identifiers.org/kegg.compound/C05582> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID1738> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q903566> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2436_r139680/DataNode/af4b4> ;
        foaf:page           <http://www.hmdb.ca/metabolites/HMDB0000118> .

<https://identifiers.org/hmdb/HMDB0012992>
        rdf:type            wp:Metabolite , wp:DataNode ;
        rdfs:label          "Leukoaminochrome" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/VGSVNUGKHOVSPK-UHFFFAOYSA-N> ;
        dc:identifier       <https://identifiers.org/hmdb/HMDB0012992> ;
        dc:source           "HMDB" ;
        dcterms:identifier  "HMDB0012992" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2436_r139680> , <http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/e306e> , <http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/cf41a> , <http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/e2a8b> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:74683> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/129893> ;
        wp:bdbHmdb          <https://identifiers.org/hmdb/HMDB0012992> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/VGSVNUGKHOVSPK-UHFFFAOYSA-N> ;
        wp:bdbKeggCompound  <https://identifiers.org/kegg.compound/C17756> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID147311> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q27144821> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2436_r139680/DataNode/fbd1e> ;
        foaf:page           <http://www.hmdb.ca/metabolites/HMDB0012992> .

<https://identifiers.org/hmdb/HMDB0002111>
        rdf:type            wp:Metabolite , wp:DataNode ;
        rdfs:label          "H₂O" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/XLYOFNOQVPJJNP-UHFFFAOYSA-N> ;
        dc:identifier       <https://identifiers.org/hmdb/HMDB0002111> ;
        dc:source           "HMDB" ;
        dcterms:identifier  "HMDB0002111" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2436_r139680> , <http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/ded6b> , <http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/b9f7e> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:15377> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/937> ;
        wp:bdbHmdb          <https://identifiers.org/hmdb/HMDB0002111> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/XLYOFNOQVPJJNP-UHFFFAOYSA-N> ;
        wp:bdbKeggCompound  <https://identifiers.org/kegg.compound/C00001> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID962> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q283> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2436_r139680/DataNode/c0681> ;
        foaf:page           <http://www.hmdb.ca/metabolites/HMDB0002111> .

<http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/efc07>
        rdf:type          wp:Catalysis , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2436_r139680> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2436_r139680/Interaction/efc07> ;
        wp:participants   <http://rdf.wikipathways.org/Pathway/WP2436_r139680/Complex/c4d5f> , <http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/d3e94> ;
        wp:source         <http://rdf.wikipathways.org/Pathway/WP2436_r139680/Complex/c4d5f> ;
        wp:target         <http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/d3e94> .

<http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/aff4f>
        rdf:type          wp:Conversion , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2436_r139680> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2436_r139680/Interaction/aff4f> ;
        wp:participants   <https://identifiers.org/wikidata/Q1981297> , <https://identifiers.org/pubchem.compound/46173450> ;
        wp:source         <https://identifiers.org/pubchem.compound/46173450> ;
        wp:target         <https://identifiers.org/wikidata/Q1981297> .

<https://identifiers.org/hmdb/HMDB0004369>
        rdf:type            wp:DataNode , wp:Metabolite ;
        rdfs:label          "N-Methylserotonin" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/ASUSBMNYRHGZIG-UHFFFAOYSA-N> ;
        dc:identifier       <https://identifiers.org/hmdb/HMDB0004369> ;
        dc:source           "HMDB" ;
        dcterms:identifier  "HMDB0004369" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2436_r139680> , <http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/b9f7e> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:48294> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/132989> ;
        wp:bdbHmdb          <https://identifiers.org/hmdb/HMDB0004369> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/ASUSBMNYRHGZIG-UHFFFAOYSA-N> ;
        wp:bdbKeggCompound  <https://identifiers.org/kegg.compound/C06212> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID150885> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q855403> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2436_r139680/DataNode/bb8d8> ;
        foaf:page           <http://www.hmdb.ca/metabolites/HMDB0004369> .

<https://identifiers.org/hmdb/HMDB0003791>
        rdf:type            wp:Metabolite , wp:DataNode ;
        rdfs:label          "DOPAL" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/IADQVXRMSNIUEL-UHFFFAOYSA-N> ;
        dc:identifier       <https://identifiers.org/hmdb/HMDB0003791> ;
        dc:source           "HMDB" ;
        dcterms:identifier  "HMDB0003791" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/ded6b> , <http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/e7a51> , <http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/bc675> , <https://identifiers.org/wikipathways/WP2436_r139680> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:27978> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/106504> ;
        wp:bdbHmdb          <https://identifiers.org/hmdb/HMDB0003791> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/IADQVXRMSNIUEL-UHFFFAOYSA-N> ;
        wp:bdbKeggCompound  <https://identifiers.org/kegg.compound/C04043> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID119219> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q4634065> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2436_r139680/DataNode/db9a2> ;
        foaf:page           <http://www.hmdb.ca/metabolites/HMDB0003791> .

<https://identifiers.org/hmdb/HMDB0000181>
        rdf:type            wp:Metabolite , wp:DataNode ;
        rdfs:label          "L-Dopa" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/WTDRDQBEARUVNC-LURJTMIESA-N> ;
        dc:identifier       <https://identifiers.org/hmdb/HMDB0000181> ;
        dc:source           "HMDB" ;
        dcterms:identifier  "HMDB0000181" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/df957> , <http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/b1b2f> , <https://identifiers.org/wikipathways/WP2436_r139680> , <http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/da696> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:15765> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/5824> ;
        wp:bdbHmdb          <https://identifiers.org/hmdb/HMDB0000181> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/WTDRDQBEARUVNC-LURJTMIESA-N> ;
        wp:bdbKeggCompound  <https://identifiers.org/kegg.compound/C00355> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID6047> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q106345614> , <http://www.wikidata.org/entity/Q300989> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2436_r139680/DataNode/a8073> ;
        foaf:page           <http://www.hmdb.ca/metabolites/HMDB0000181> .

<http://rdf.wikipathways.org/Pathway/WP2436_r139680/Complex/af0ea>
        rdf:type          wp:Complex , wp:DataNode ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2436_r139680> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2436_r139680/Group/af0ea> ;
        wp:participants   <https://identifiers.org/ncbigene/5568> , <https://identifiers.org/ncbigene/5567> , <https://identifiers.org/ncbigene/5566> .

<https://identifiers.org/chebi/CHEBI:29033>
        rdf:type            wp:Metabolite , wp:DataNode ;
        rdfs:label          "iron(2+)" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/CWYNVVGOOAEACU-UHFFFAOYSA-N> ;
        dc:identifier       <https://identifiers.org/chebi/CHEBI:29033> ;
        dc:source           "ChEBI" ;
        dcterms:identifier  "CHEBI:29033" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2436_r139680> , <http://rdf.wikipathways.org/Pathway/WP2436_r139680/Complex/bbcc1> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:29033> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/25394> ;
        wp:bdbHmdb          <https://identifiers.org/hmdb/HMDB0000692> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/CWYNVVGOOAEACU-UHFFFAOYSA-N> ;
        wp:bdbKeggCompound  <https://identifiers.org/kegg.compound/C14818> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID27284> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q428946> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2436_r139680/DataNode/e1c50> ;
        foaf:page           <https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:29033> .

<https://identifiers.org/hmdb/HMDB0000125>
        rdf:type            wp:Metabolite , wp:DataNode ;
        rdfs:label          "Glutathione" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/RWSXRVCMGQZWBV-WDSKDSINSA-N> ;
        dc:identifier       <https://identifiers.org/hmdb/HMDB0000125> ;
        dc:source           "HMDB" ;
        dcterms:identifier  "HMDB0000125" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2436_r139680> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:16856> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/111188> ;
        wp:bdbHmdb          <https://identifiers.org/hmdb/HMDB0000125> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/RWSXRVCMGQZWBV-WDSKDSINSA-N> ;
        wp:bdbKeggCompound  <https://identifiers.org/kegg.compound/C00051> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID124886> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q116907> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2436_r139680/DataNode/dfa22> ;
        foaf:page           <http://www.hmdb.ca/metabolites/HMDB0000125> .

<http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/b1b84>
        rdf:type          wp:Conversion , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2436_r139680> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2436_r139680/Interaction/b1b84> ;
        wp:participants   <https://identifiers.org/pubchem.compound/46173450> , <https://identifiers.org/hmdb/HMDB0001253> ;
        wp:source         <https://identifiers.org/hmdb/HMDB0001253> ;
        wp:target         <https://identifiers.org/pubchem.compound/46173450> .

<http://rdf.wikipathways.org/Pathway/WP2436_r139680/Complex/bbcc1>
        rdf:type          wp:Complex , wp:DataNode ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/e13b9> , <https://identifiers.org/wikipathways/WP2436_r139680> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2436_r139680/Group/bbcc1> ;
        wp:participants   <https://identifiers.org/ncbigene/7054> , <https://identifiers.org/chebi/CHEBI:29033> .

<http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/d29f2>
        rdf:type          wp:Conversion , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2436_r139680> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2436_r139680/Interaction/d29f2> ;
        wp:participants   <https://identifiers.org/hmdb/HMDB0000118> , <https://identifiers.org/hmdb/HMDB0005175> ;
        wp:source         <https://identifiers.org/hmdb/HMDB0005175> ;
        wp:target         <https://identifiers.org/hmdb/HMDB0000118> .

<http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/d6472>
        rdf:type          wp:Conversion , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2436_r139680> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2436_r139680/Interaction/d6472> ;
        wp:participants   <https://identifiers.org/hmdb/HMDB0001430> , <https://identifiers.org/hmdb/HMDB0004067> ;
        wp:source         <https://identifiers.org/hmdb/HMDB0004067> ;
        wp:target         <https://identifiers.org/hmdb/HMDB0001430> .

<http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/b9f7e>
        rdf:type          wp:Interaction , wp:DirectedInteraction , wp:Conversion ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2436_r139680> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2436_r139680/Interaction/d9f90> , <http://rdf.wikipathways.org/Pathway/WP2436_r139680/Interaction/e5641> , <http://rdf.wikipathways.org/Pathway/WP2436_r139680/Interaction/d9d59> , <http://rdf.wikipathways.org/Pathway/WP2436_r139680/Interaction/b9f7e> ;
        wp:participants   <https://identifiers.org/chebi/CHEBI:34718> , <https://identifiers.org/hmdb/HMDB0001377> , <https://identifiers.org/hmdb/HMDB0002111> , <https://identifiers.org/hmdb/HMDB0004369> , <https://identifiers.org/hmdb/HMDB0003125> ;
        wp:source         <https://identifiers.org/chebi/CHEBI:34718> , <https://identifiers.org/hmdb/HMDB0001377> , <https://identifiers.org/hmdb/HMDB0002111> ;
        wp:target         <https://identifiers.org/hmdb/HMDB0003125> , <https://identifiers.org/hmdb/HMDB0004369> .

<http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/e2a8b>
        rdf:type          wp:Conversion , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2436_r139680> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2436_r139680/Interaction/e2a8b> ;
        wp:participants   <https://identifiers.org/pubchem.compound/170262> , <https://identifiers.org/hmdb/HMDB0012992> ;
        wp:source         <https://identifiers.org/hmdb/HMDB0012992> ;
        wp:target         <https://identifiers.org/pubchem.compound/170262> .

<https://identifiers.org/ncbigene/7299>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "TYR" ;
        dc:identifier       <https://identifiers.org/ncbigene/7299> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "7299" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/e17bb> , <https://identifiers.org/wikipathways/WP2436_r139680> , <http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/ac472> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000077498> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/7299> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/TYR> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/P14679> , <https://identifiers.org/uniprot/L8B082> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2436_r139680/DataNode/dfece> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P14679> , <http://purl.uniprot.org/uniprot/L8B082> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/7299> .

<https://identifiers.org/ncbigene/5566>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "PRKACA" ;
        dc:identifier       <https://identifiers.org/ncbigene/5566> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "5566" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2436_r139680> , <http://rdf.wikipathways.org/Pathway/WP2436_r139680/Complex/af0ea> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000072062> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/5566> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/PRKACA> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A024R7J0> , <https://identifiers.org/uniprot/K7ERP6> , <https://identifiers.org/uniprot/Q15136> , <https://identifiers.org/uniprot/A0A7I2YQ82> , <https://identifiers.org/uniprot/P17612> , <https://identifiers.org/uniprot/K7ENJ5> , <https://identifiers.org/uniprot/A0A7I2V5J4> , <https://identifiers.org/uniprot/A0A8V8TL59> , <https://identifiers.org/uniprot/K7EMV1> , <https://identifiers.org/uniprot/B7Z708> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2436_r139680/DataNode/b64a9> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A8V8TL59> , <http://purl.uniprot.org/uniprot/P17612> , <http://purl.uniprot.org/uniprot/K7EMV1> , <http://purl.uniprot.org/uniprot/B7Z708> , <http://purl.uniprot.org/uniprot/K7ENJ5> , <http://purl.uniprot.org/uniprot/Q15136> , <http://purl.uniprot.org/uniprot/K7ERP6> , <http://purl.uniprot.org/uniprot/A0A7I2V5J4> , <http://purl.uniprot.org/uniprot/A0A024R7J0> , <http://purl.uniprot.org/uniprot/A0A7I2YQ82> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/5566> .

<http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/bc675>
        rdf:type          wp:Conversion , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2436_r139680> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2436_r139680/Interaction/bc675> ;
        wp:participants   <https://identifiers.org/hmdb/HMDB0005784> , <https://identifiers.org/hmdb/HMDB0003791> ;
        wp:source         <https://identifiers.org/hmdb/HMDB0003791> ;
        wp:target         <https://identifiers.org/hmdb/HMDB0005784> .

<http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/e306e>
        rdf:type          wp:Conversion , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2436_r139680> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2436_r139680/Interaction/e306e> ;
        wp:participants   <https://identifiers.org/hmdb/HMDB0012992> , <https://identifiers.org/pubchem.compound/170262> ;
        wp:source         <https://identifiers.org/pubchem.compound/170262> ;
        wp:target         <https://identifiers.org/hmdb/HMDB0012992> .

<https://identifiers.org/hmdb/HMDB0000158>
        rdf:type            wp:Metabolite , wp:DataNode ;
        rdfs:label          "L-Tyrosine" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/OUYCCCASQSFEME-QMMMGPOBSA-N> ;
        dc:identifier       <https://identifiers.org/hmdb/HMDB0000158> ;
        dc:source           "HMDB" ;
        dcterms:identifier  "HMDB0000158" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/b1b2f> , <https://identifiers.org/wikipathways/WP2436_r139680> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:17895> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/5833> ;
        wp:bdbHmdb          <https://identifiers.org/hmdb/HMDB0000158> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/OUYCCCASQSFEME-QMMMGPOBSA-N> ;
        wp:bdbKeggCompound  <https://identifiers.org/kegg.compound/C00082> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID6057> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q188017> , <http://www.wikidata.org/entity/Q106345477> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2436_r139680/DataNode/d9e3c> ;
        foaf:page           <http://www.hmdb.ca/metabolites/HMDB0000158> .

obo:NCBITaxon_9606  obo:NCIT_C179773  "9606" .

<https://identifiers.org/hmdb/HMDB0000073>
        rdf:type            wp:Metabolite , wp:DataNode ;
        rdfs:label          "Dopamine" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/VYFYYTLLBUKUHU-UHFFFAOYSA-N> ;
        dc:identifier       <https://identifiers.org/hmdb/HMDB0000073> ;
        dc:source           "HMDB" ;
        dcterms:identifier  "HMDB0000073" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/da696> , <http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/ded6b> , <http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/ea31a> , <https://identifiers.org/wikipathways/WP2436_r139680> , <http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/a19ed> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:18243> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/661> ;
        wp:bdbHmdb          <https://identifiers.org/hmdb/HMDB0000073> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/VYFYYTLLBUKUHU-UHFFFAOYSA-N> ;
        wp:bdbKeggCompound  <https://identifiers.org/kegg.compound/C03758> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID681> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q170304> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2436_r139680/DataNode/a8e83> ;
        foaf:page           <http://www.hmdb.ca/metabolites/HMDB0000073> .

<http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/da696>
        rdf:type          wp:Conversion , wp:Interaction , wp:DirectedInteraction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2436_r139680> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2436_r139680/Interaction/d9cb4> , <http://rdf.wikipathways.org/Pathway/WP2436_r139680/Interaction/da696> ;
        wp:participants   <https://identifiers.org/hmdb/HMDB0000073> , <https://identifiers.org/hmdb/HMDB0001967> , <https://identifiers.org/hmdb/HMDB0000181> ;
        wp:source         <https://identifiers.org/hmdb/HMDB0001967> , <https://identifiers.org/hmdb/HMDB0000181> ;
        wp:target         <https://identifiers.org/hmdb/HMDB0000073> .

<http://rdf.wikipathways.org/Pathway/WP2436_r139680/Complex/cfdf6>
        rdf:type          wp:Complex , wp:DataNode ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2436_r139680> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2436_r139680/Group/cfdf6> ;
        wp:participants   <https://identifiers.org/ncbigene/5516> , <https://identifiers.org/ncbigene/5515> .

<https://identifiers.org/chebi/CHEBI:34718>
        rdf:type            wp:Metabolite , wp:DataNode ;
        rdfs:label          "1-chloro-2,4-dinitrobenzene" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/VYZAHLCBVHPDDF-UHFFFAOYSA-N> ;
        dc:identifier       <https://identifiers.org/chebi/CHEBI:34718> ;
        dc:source           "ChEBI" ;
        dcterms:identifier  "CHEBI:34718" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2436_r139680> , <http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/b9f7e> , <http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/ea31a> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:34718> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/13868426> ;
        wp:bdbHmdb          <https://identifiers.org/hmdb/HMDB0243844> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/VYZAHLCBVHPDDF-UHFFFAOYSA-N> ;
        wp:bdbKeggCompound  <https://identifiers.org/kegg.compound/C14397> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID6> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q209216> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2436_r139680/DataNode/ef211> ;
        foaf:page           <https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:34718> .

<https://identifiers.org/wikipathways/WP2436>
        pav:hasVersion  <https://identifiers.org/wikipathways/WP2436_r139680> .

<http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/ed31f>
        rdf:type          wp:Stimulation , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2436_r139680> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2436_r139680/Interaction/ed31f> ;
        wp:participants   <https://identifiers.org/chebi/CHEBI:26523> , <https://identifiers.org/hmdb/HMDB0003125> ;
        wp:source         <https://identifiers.org/hmdb/HMDB0003125> ;
        wp:target         <https://identifiers.org/chebi/CHEBI:26523> .

<http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/bcf1b>
        rdf:type          wp:Conversion , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2436_r139680> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2436_r139680/Interaction/bcf1b> ;
        wp:participants   <https://identifiers.org/hmdb/HMDB0004058> , <https://identifiers.org/hmdb/HMDB0001430> ;
        wp:source         <https://identifiers.org/hmdb/HMDB0001430> ;
        wp:target         <https://identifiers.org/hmdb/HMDB0004058> .

<https://identifiers.org/hmdb/HMDB0001185>
        rdf:type            wp:Metabolite , wp:DataNode ;
        rdfs:label          "S-Adenosylmethionine" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/MEFKEPWMEQBLKI-AIRLBKTGSA-N> ;
        dc:identifier       <https://identifiers.org/hmdb/HMDB0001185> ;
        dc:source           "HMDB" ;
        dcterms:identifier  "HMDB0001185" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2436_r139680> , <http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/ea31a> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:15414> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/21169292> ;
        wp:bdbHmdb          <https://identifiers.org/hmdb/HMDB0001185> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/MEFKEPWMEQBLKI-AIRLBKTGSA-O> ;
        wp:bdbKeggCompound  <https://identifiers.org/kegg.compound/C00019> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID34756> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q106314841> , <http://www.wikidata.org/entity/Q56071634> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2436_r139680/DataNode/c982b> ;
        foaf:page           <http://www.hmdb.ca/metabolites/HMDB0001185> .

<https://identifiers.org/hmdb/HMDB0005175>
        rdf:type            wp:Metabolite , wp:DataNode ;
        rdfs:label          "Homovanillin" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/GOQGGGANVKPMNH-UHFFFAOYSA-N> ;
        dc:identifier       <https://identifiers.org/hmdb/HMDB0005175> ;
        dc:source           "HMDB" ;
        dcterms:identifier  "HMDB0005175" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/d29f2> , <https://identifiers.org/wikipathways/WP2436_r139680> , <http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/d3e94> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:28111> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/133331> ;
        wp:bdbHmdb          <https://identifiers.org/hmdb/HMDB0005175> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/GOQGGGANVKPMNH-UHFFFAOYSA-N> ;
        wp:bdbKeggCompound  <https://identifiers.org/kegg.compound/C05581> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID151276> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q27103508> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2436_r139680/DataNode/a16d9> ;
        foaf:page           <http://www.hmdb.ca/metabolites/HMDB0005175> .

<https://identifiers.org/hmdb/HMDB0001377>
        rdf:type            wp:DataNode , wp:Metabolite ;
        rdfs:label          "O₂" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/MYMOFIZGZYHOMD-UHFFFAOYSA-N> ;
        dc:identifier       <https://identifiers.org/hmdb/HMDB0001377> ;
        dc:source           "HMDB" ;
        dcterms:identifier  "HMDB0001377" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/b9f7e> , <https://identifiers.org/wikipathways/WP2436_r139680> , <http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/ded6b> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:15379> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/952> ;
        wp:bdbHmdb          <https://identifiers.org/hmdb/HMDB0001377> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/MYMOFIZGZYHOMD-UHFFFAOYSA-N> ;
        wp:bdbKeggCompound  <https://identifiers.org/kegg.compound/C00007> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID977> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q5203615> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2436_r139680/DataNode/ee731> ;
        foaf:page           <http://www.hmdb.ca/metabolites/HMDB0001377> .

<https://identifiers.org/pmc/PMC9015122>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed Central" ;
        dcterms:identifier  "PMC9015122" ;
        cito:cites          <https://identifiers.org/wikipathways/WP2436> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/PMC9015122> .

<https://identifiers.org/hmdb/HMDB0001430>
        rdf:type            wp:DataNode , wp:Metabolite ;
        rdfs:label          "L-Dopachrome" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/VJNCICVKUHKIIV-LURJTMIESA-N> ;
        dc:identifier       <https://identifiers.org/hmdb/HMDB0001430> ;
        dc:source           "HMDB" ;
        dcterms:identifier  "HMDB0001430" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/bcf1b> , <https://identifiers.org/wikipathways/WP2436_r139680> , <http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/fb2de> , <http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/d6472> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:15772> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/4573572> ;
        wp:bdbHmdb          <https://identifiers.org/hmdb/HMDB0001430> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/VJNCICVKUHKIIV-LURJTMIESA-N> ;
        wp:bdbKeggCompound  <https://identifiers.org/kegg.compound/C01693> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID5459802> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q27098224> , <http://www.wikidata.org/entity/Q47459671> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2436_r139680/DataNode/c5d27> ;
        foaf:page           <http://www.hmdb.ca/metabolites/HMDB0001430> .

<https://identifiers.org/chebi/CHEBI:16852>
        rdf:type            wp:DataNode , wp:Metabolite ;
        rdfs:label          "L-Dopa quinone" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/AHMIDUVKSGCHAU-LURJTMIESA-N> ;
        dc:identifier       <https://identifiers.org/chebi/CHEBI:16852> ;
        dc:source           "ChEBI" ;
        dcterms:identifier  "CHEBI:16852" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/df957> , <http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/c432e> , <https://identifiers.org/wikipathways/WP2436_r139680> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:16852> , <https://identifiers.org/chebi/CHEBI:57924> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/388447> ;
        wp:bdbHmdb          <https://identifiers.org/hmdb/HMDB0001229> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/AHMIDUVKSGCHAU-LURJTMIESA-N> ;
        wp:bdbKeggCompound  <https://identifiers.org/kegg.compound/C00822> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID439316> , <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID44229226> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q11694846> , <http://www.wikidata.org/entity/Q106315140> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2436_r139680/DataNode/c9aca> ;
        foaf:page           <https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:16852> .

<http://rdf.wikipathways.org/Pathway/WP2436_r139680/ComplexBinding/f0966>
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<https://identifiers.org/wikipathways/WP2436_r139680>
        rdf:type                skos:Collection , wp:Pathway ;
        dc:identifier           <https://identifiers.org/wikipathways/WP2436> ;
        dc:source               "WikiPathways" ;
        dc:title                "Dopamine metabolism"@en ;
        dcterms:description     "Dopamine is an organic chemical of the catecholamine and phenethylamine families that plays several important roles in the brain and body. It is an amine synthesized by removing a carboxyl group from a molecule of its precursor chemical L-DOPA, which is synthesized in the brain and kidneys. Dopamine is also synthesized in plants and most animals. \nThe dopamine system plays a central role in several significant medical conditions, including Parkinson's disease. Parkinson's disease is an age-related disorder characterized by movement disorders such as stiffness of the body, slowing of movement, and trembling of limbs when they are not in use. The main symptoms are caused by the loss of dopamine-secreting cells in the substantia nigra. These dopamine cells are especially vulnerable to damage, and a variety of insults, including encephalitis (as depicted in the book and movie \"Awakenings\"), repeated sports-related concussions, and some forms of chemical poisoning such as MPTP, can lead to substantial cell loss, producing a parkinsonian syndrome that is similar in its main features to Parkinson's disease.\nThe most widely used treatment for parkinsonism is administration of L-DOPA, the metabolic precursor for dopamine. L-DOPA is converted to dopamine in the brain and various parts of the body by the enzyme DOPA decarboxylase. L-DOPA is used rather than dopamine itself because, unlike dopamine, it is capable of crossing the blood-brain barrier.\nDescription source: [Wikipedia](https://en.wikipedia.org/wiki/Dopamine).\n\nProteins on this pathway have targeted assays available via the [CPTAC Assay Portal](https://assays.cancer.gov/available_assays?wp_id=WP2436)." ;
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        dcterms:references      <https://identifiers.org/pubmed/24409201> ;
        cito:cites              <https://identifiers.org/pubmed/24409201> ;
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        wp:isAbout              <http://rdf.wikipathways.org/Pathway/WP2436_r139680> ;
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        wp:organism             obo:NCBITaxon_9606 ;
        wp:organismName         "Homo sapiens" ;
        wp:pathwayOntologyTag   obo:PW_0002511 , obo:PW_0000002 , obo:PW_0000802 , obo:PW_0000394 , obo:PW_0000409 ;
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<https://identifiers.org/pmc/PMC9524193>
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        cito:cites          <https://identifiers.org/wikipathways/WP2436> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/PMC9524193> .

<https://identifiers.org/ncbigene/5516>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "PPP2CB" ;
        dc:identifier       <https://identifiers.org/ncbigene/5516> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "5516" ;
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        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000104695> ;
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        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A140VJS0> , <https://identifiers.org/uniprot/P62714> , <https://identifiers.org/uniprot/E5RJX4> , <https://identifiers.org/uniprot/H0YC23> , <https://identifiers.org/uniprot/H0YBN9> , <https://identifiers.org/uniprot/E5RHC1> , <https://identifiers.org/uniprot/E5RFI3> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2436_r139680/DataNode/a97fa> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A140VJS0> , <http://purl.uniprot.org/uniprot/E5RFI3> , <http://purl.uniprot.org/uniprot/E5RHC1> , <http://purl.uniprot.org/uniprot/H0YC23> , <http://purl.uniprot.org/uniprot/E5RJX4> , <http://purl.uniprot.org/uniprot/H0YBN9> , <http://purl.uniprot.org/uniprot/P62714> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/5516> .

<https://identifiers.org/wikidata/Q1981297>
        rdf:type            wp:DataNode , wp:Metabolite ;
        rdfs:label          "Neuromelanin" ;
        dc:identifier       <https://identifiers.org/wikidata/Q1981297> ;
        dc:source           "Wikidata" ;
        dcterms:identifier  "Q1981297" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/aff4f> , <http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/b8a34> , <https://identifiers.org/wikipathways/WP2436_r139680> ;
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        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2436_r139680/DataNode/f81cf> ;
        foaf:page           <https://scholia.toolforge.org/Q1981297> .

<https://identifiers.org/chebi/CHEBI:41941>
        rdf:type            wp:DataNode , wp:Metabolite ;
        rdfs:label          "DOPAC" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/CFFZDZCDUFSOFZ-UHFFFAOYSA-N> ;
        dc:identifier       <https://identifiers.org/chebi/CHEBI:41941> ;
        dc:source           "ChEBI" ;
        dcterms:identifier  "CHEBI:41941" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/cfd80> , <https://identifiers.org/wikipathways/WP2436_r139680> , <http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/e7a51> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:41941> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/532> ;
        wp:bdbHmdb          <https://identifiers.org/hmdb/HMDB0001336> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/CFFZDZCDUFSOFZ-UHFFFAOYSA-N> ;
        wp:bdbKeggCompound  <https://identifiers.org/kegg.compound/C01161> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID547> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q4634071> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2436_r139680/DataNode/d9e04> ;
        foaf:page           <https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:41941> .

<http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/df957>
        rdf:type          wp:Conversion , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2436_r139680> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2436_r139680/Interaction/df957> ;
        wp:participants   <https://identifiers.org/chebi/CHEBI:16852> , <https://identifiers.org/hmdb/HMDB0000181> ;
        wp:source         <https://identifiers.org/hmdb/HMDB0000181> ;
        wp:target         <https://identifiers.org/chebi/CHEBI:16852> .

<http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/ea31a>
        rdf:type          wp:DirectedInteraction , wp:Conversion , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2436_r139680> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2436_r139680/Interaction/bfd26> , <http://rdf.wikipathways.org/Pathway/WP2436_r139680/Interaction/ea31a> , <http://rdf.wikipathways.org/Pathway/WP2436_r139680/Interaction/e8fb3> ;
        wp:participants   <https://identifiers.org/chebi/CHEBI:34718> , <https://identifiers.org/hmdb/HMDB0000939> , <https://identifiers.org/hmdb/HMDB0001185> , <https://identifiers.org/hmdb/HMDB0000073> ;
        wp:source         <https://identifiers.org/hmdb/HMDB0000073> , <https://identifiers.org/hmdb/HMDB0001185> ;
        wp:target         <https://identifiers.org/hmdb/HMDB0000939> , <https://identifiers.org/chebi/CHEBI:34718> .

<https://identifiers.org/hmdb/HMDB0000051>
        rdf:type            wp:DataNode , wp:Metabolite ;
        rdfs:label          "Ammonia" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/QGZKDVFQNNGYKY-UHFFFAOYSA-N> ;
        dc:identifier       <https://identifiers.org/hmdb/HMDB0000051> ;
        dc:source           "HMDB" ;
        dcterms:identifier  "HMDB0000051" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2436_r139680> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:16134> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/217> ;
        wp:bdbHmdb          <https://identifiers.org/hmdb/HMDB0000051> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/QGZKDVFQNNGYKY-UHFFFAOYSA-N> ;
        wp:bdbKeggCompound  <https://identifiers.org/kegg.compound/C00014> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID222> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q4087> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2436_r139680/DataNode/d2ff5> ;
        foaf:page           <http://www.hmdb.ca/metabolites/HMDB0000051> .

<http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/d3e94>
        rdf:type          wp:Conversion , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2436_r139680> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2436_r139680/Interaction/d3e94> ;
        wp:participants   <https://identifiers.org/hmdb/HMDB0005175> , <https://identifiers.org/hmdb/HMDB0000022> ;
        wp:source         <https://identifiers.org/hmdb/HMDB0000022> ;
        wp:target         <https://identifiers.org/hmdb/HMDB0005175> .

<https://identifiers.org/pubchem.compound/170262>
        rdf:type            wp:Metabolite , wp:DataNode ;
        rdfs:label          "Dopaminochrome" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/XDEURYRPQDIBSL-UHFFFAOYSA-N> ;
        dc:identifier       <https://identifiers.org/pubchem.compound/170262> ;
        dc:source           "PubChem-compound" ;
        dcterms:identifier  "170262" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/e2a8b> , <https://identifiers.org/wikipathways/WP2436_r139680> , <http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/e306e> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:189002> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/148871> ;
        wp:bdbHmdb          <https://identifiers.org/hmdb/HMDB0248311> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/XDEURYRPQDIBSL-UHFFFAOYSA-N> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID170262> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q33624244> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2436_r139680/DataNode/fdd3b> ;
        foaf:page           <http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=170262> .

<http://rdf.wikipathways.org/Pathway/WP2436_r139680/ComplexBinding/bbcc1>
        rdf:type          wp:ComplexBinding , wp:Binding , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2436_r139680> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2436_r139680/Group/bbcc1> ;
        wp:participants   <https://identifiers.org/ncbigene/7054> , <https://identifiers.org/chebi/CHEBI:29033> , <http://rdf.wikipathways.org/Pathway/WP2436_r139680/Complex/bbcc1> .

<https://identifiers.org/hmdb/HMDB0001248>
        rdf:type            wp:DataNode , wp:Metabolite ;
        rdfs:label          "FAD" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/VWWQXMAJTJZDQX-UYBVJOGSSA-N> ;
        dc:identifier       <https://identifiers.org/hmdb/HMDB0001248> ;
        dc:source           "HMDB" ;
        dcterms:identifier  "HMDB0001248" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2436_r139680> , <http://rdf.wikipathways.org/Pathway/WP2436_r139680/Complex/f0e09> , <http://rdf.wikipathways.org/Pathway/WP2436_r139680/Complex/c4d5f> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:16238> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/559059> ;
        wp:bdbHmdb          <https://identifiers.org/hmdb/HMDB0001248> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/VWWQXMAJTJZDQX-UYBVJOGSSA-N> ;
        wp:bdbKeggCompound  <https://identifiers.org/kegg.compound/C00016> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID643975> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q28746> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2436_r139680/DataNode/c0777> , <http://rdf.wikipathways.org/Pathway/WP2436_r139680/DataNode/fd81f> ;
        foaf:page           <http://www.hmdb.ca/metabolites/HMDB0001248> .

<http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/e17bb>
        rdf:type          wp:Catalysis , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2436_r139680> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2436_r139680/Interaction/e17bb> ;
        wp:participants   <https://identifiers.org/ncbigene/7299> , <http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/b1b2f> ;
        wp:source         <https://identifiers.org/ncbigene/7299> ;
        wp:target         <http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/b1b2f> .

<https://identifiers.org/hmdb/HMDB0004067>
        rdf:type            wp:Metabolite , wp:DataNode ;
        rdfs:label          "Leucodopachrome" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/JDWYRSDDJVCWPB-LURJTMIESA-N> ;
        dc:identifier       <https://identifiers.org/hmdb/HMDB0004067> ;
        dc:source           "HMDB" ;
        dcterms:identifier  "HMDB0004067" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2436_r139680> , <http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/d6472> , <http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/c432e> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:60872> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/141655> ;
        wp:bdbHmdb          <https://identifiers.org/hmdb/HMDB0004067> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/JDWYRSDDJVCWPB-LURJTMIESA-N> ;
        wp:bdbKeggCompound  <https://identifiers.org/kegg.compound/C05604> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID161255> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q15491505> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2436_r139680/DataNode/b02d5> ;
        foaf:page           <http://www.hmdb.ca/metabolites/HMDB0004067> .

<https://identifiers.org/hmdb/HMDB0001967>
        rdf:type            wp:DataNode , wp:Metabolite ;
        rdfs:label          "CO₂" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/CURLTUGMZLYLDI-UHFFFAOYSA-N> ;
        dc:identifier       <https://identifiers.org/hmdb/HMDB0001967> ;
        dc:source           "HMDB" ;
        dcterms:identifier  "HMDB0001967" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/da696> , <https://identifiers.org/wikipathways/WP2436_r139680> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:16526> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/274> ;
        wp:bdbHmdb          <https://identifiers.org/hmdb/HMDB0001967> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/CURLTUGMZLYLDI-UHFFFAOYSA-N> ;
        wp:bdbKeggCompound  <https://identifiers.org/kegg.compound/C00011> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID280> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q1997> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2436_r139680/DataNode/f257f> ;
        foaf:page           <http://www.hmdb.ca/metabolites/HMDB0001967> .

<https://identifiers.org/pmc/PMC12854766>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed Central" ;
        dcterms:identifier  "PMC12854766" ;
        cito:cites          <https://identifiers.org/wikipathways/WP2436> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/PMC12854766> .

<http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/e3be5>
        rdf:type          wp:Catalysis , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2436_r139680> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2436_r139680/Interaction/e3be5> ;
        wp:participants   <https://identifiers.org/ncbigene/1312> , <http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/ea31a> ;
        wp:source         <https://identifiers.org/ncbigene/1312> ;
        wp:target         <http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/ea31a> .

<http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/a07f7>
        rdf:type          wp:Catalysis , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2436_r139680> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2436_r139680/Interaction/a07f7> ;
        wp:participants   <http://rdf.wikipathways.org/Pathway/WP2436_r139680/Complex/c4d5f> , <http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/b9f7e> ;
        wp:source         <http://rdf.wikipathways.org/Pathway/WP2436_r139680/Complex/c4d5f> ;
        wp:target         <http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/b9f7e> .

<http://rdf.wikipathways.org/Pathway/WP2436_r139680/Complex/f0e09>
        rdf:type          wp:Complex , wp:DataNode ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/a8d6e> , <http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/e8bab> , <https://identifiers.org/wikipathways/WP2436_r139680> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2436_r139680/Group/f0e09> ;
        wp:participants   <https://identifiers.org/hmdb/HMDB0001248> , <https://identifiers.org/ncbigene/4129> .

<http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/af572>
        rdf:type          wp:Catalysis , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2436_r139680> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2436_r139680/Interaction/af572> ;
        wp:participants   <http://rdf.wikipathways.org/Pathway/WP2436_r139680/Complex/c4d5f> , <http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/ded6b> ;
        wp:source         <http://rdf.wikipathways.org/Pathway/WP2436_r139680/Complex/c4d5f> ;
        wp:target         <http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/ded6b> .

<http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/a1345>
        rdf:type          wp:Catalysis , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2436_r139680> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2436_r139680/Interaction/a1345> ;
        wp:participants   <https://identifiers.org/ncbigene/1312> , <http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/a19ed> ;
        wp:source         <https://identifiers.org/ncbigene/1312> ;
        wp:target         <http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/a19ed> .

<http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/e7a51>
        rdf:type          wp:Conversion , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2436_r139680> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2436_r139680/Interaction/e7a51> ;
        wp:participants   <https://identifiers.org/chebi/CHEBI:41941> , <https://identifiers.org/hmdb/HMDB0003791> ;
        wp:source         <https://identifiers.org/hmdb/HMDB0003791> ;
        wp:target         <https://identifiers.org/chebi/CHEBI:41941> .

<https://identifiers.org/ncbigene/5515>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "PPP2CA" ;
        dc:identifier       <https://identifiers.org/ncbigene/5515> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "5515" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2436_r139680/Complex/cfdf6> , <https://identifiers.org/wikipathways/WP2436_r139680> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000113575> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/5515> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/PPP2CA> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/B3KQ51> , <https://identifiers.org/uniprot/A0A8V8TRA6> , <https://identifiers.org/uniprot/A0A8V8TQA1> , <https://identifiers.org/uniprot/E7ESG8> , <https://identifiers.org/uniprot/P67775> , <https://identifiers.org/uniprot/A0A8V8TQU8> , <https://identifiers.org/uniprot/A0A8V8TRB3> , <https://identifiers.org/uniprot/B3KUN1> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2436_r139680/DataNode/f4e0d> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A8V8TQA1> , <http://purl.uniprot.org/uniprot/A0A8V8TRB3> , <http://purl.uniprot.org/uniprot/P67775> , <http://purl.uniprot.org/uniprot/B3KUN1> , <http://purl.uniprot.org/uniprot/A0A8V8TQU8> , <http://purl.uniprot.org/uniprot/A0A8V8TRA6> , <http://purl.uniprot.org/uniprot/B3KQ51> , <http://purl.uniprot.org/uniprot/E7ESG8> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/5515> .

<http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/c432e>
        rdf:type          wp:Conversion , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2436_r139680> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2436_r139680/Interaction/c432e> ;
        wp:participants   <https://identifiers.org/hmdb/HMDB0004067> , <https://identifiers.org/chebi/CHEBI:16852> ;
        wp:source         <https://identifiers.org/chebi/CHEBI:16852> ;
        wp:target         <https://identifiers.org/hmdb/HMDB0004067> .

<http://rdf.wikipathways.org/Pathway/WP2436_r139680/ComplexBinding/c4d5f>
        rdf:type          wp:ComplexBinding , wp:Binding , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2436_r139680> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2436_r139680/Group/c4d5f> ;
        wp:participants   <https://identifiers.org/ncbigene/4128> , <https://identifiers.org/hmdb/HMDB0001248> , <http://rdf.wikipathways.org/Pathway/WP2436_r139680/Complex/c4d5f> .

<http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/ae7ba>
        rdf:type          wp:Catalysis , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2436_r139680> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2436_r139680/Interaction/ae7ba> ;
        wp:participants   <http://rdf.wikipathways.org/Pathway/WP2436_r139680/Complex/f0966> , <http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/da696> ;
        wp:source         <http://rdf.wikipathways.org/Pathway/WP2436_r139680/Complex/f0966> ;
        wp:target         <http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/da696> .

<https://identifiers.org/hmdb/HMDB0000939>
        rdf:type            wp:DataNode , wp:Metabolite ;
        rdfs:label          "S-Adenosylhomocysteine" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/ZJUKTBDSGOFHSH-WFMPWKQPSA-N> ;
        dc:identifier       <https://identifiers.org/hmdb/HMDB0000939> ;
        dc:source           "HMDB" ;
        dcterms:identifier  "HMDB0000939" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2436_r139680> , <http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/ea31a> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:16680> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/388301> ;
        wp:bdbHmdb          <https://identifiers.org/hmdb/HMDB0000939> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/ZJUKTBDSGOFHSH-WFMPWKQPSA-N> ;
        wp:bdbKeggCompound  <https://identifiers.org/kegg.compound/C00021> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID439155> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q307434> , <http://www.wikidata.org/entity/Q106345616> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2436_r139680/DataNode/b870c> ;
        foaf:page           <http://www.hmdb.ca/metabolites/HMDB0000939> .

<https://identifiers.org/ncbigene/1312>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "COMT" ;
        dc:identifier       <https://identifiers.org/ncbigene/1312> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "1312" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/e3be5> , <http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/a1345> , <https://identifiers.org/wikipathways/WP2436_r139680> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000093010> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/1312> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/COMT> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A7I2V370> , <https://identifiers.org/uniprot/A0A140VJG8> , <https://identifiers.org/uniprot/H7BZ45> , <https://identifiers.org/uniprot/E7EMS6> , <https://identifiers.org/uniprot/E7EUU8> , <https://identifiers.org/uniprot/A0A7I2V3G7> , <https://identifiers.org/uniprot/P21964> , <https://identifiers.org/uniprot/F8WBW9> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2436_r139680/DataNode/d4a71> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/F8WBW9> , <http://purl.uniprot.org/uniprot/A0A7I2V370> , <http://purl.uniprot.org/uniprot/E7EUU8> , <http://purl.uniprot.org/uniprot/A0A7I2V3G7> , <http://purl.uniprot.org/uniprot/H7BZ45> , <http://purl.uniprot.org/uniprot/E7EMS6> , <http://purl.uniprot.org/uniprot/P21964> , <http://purl.uniprot.org/uniprot/A0A140VJG8> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/1312> .

<https://identifiers.org/hmdb/HMDB0000022>
        rdf:type            wp:Metabolite , wp:DataNode ;
        rdfs:label          "3-Methoxytyramine" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/DIVQKHQLANKJQO-UHFFFAOYSA-N> ;
        dc:identifier       <https://identifiers.org/hmdb/HMDB0000022> ;
        dc:source           "HMDB" ;
        dcterms:identifier  "HMDB0000022" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/a19ed> , <http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/d3e94> , <https://identifiers.org/wikipathways/WP2436_r139680> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:742324> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/1606> ;
        wp:bdbHmdb          <https://identifiers.org/hmdb/HMDB0000022> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/DIVQKHQLANKJQO-UHFFFAOYSA-N> ;
        wp:bdbKeggCompound  <https://identifiers.org/kegg.compound/C05587> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID1669> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q4634167> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2436_r139680/DataNode/f098a> ;
        foaf:page           <http://www.hmdb.ca/metabolites/HMDB0000022> .

<https://identifiers.org/hmdb/HMDB0012219>
        rdf:type            wp:DataNode , wp:Metabolite ;
        rdfs:label          "Dopamine quinone" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/PQPXZWUZIOASKS-UHFFFAOYSA-N> ;
        dc:identifier       <https://identifiers.org/hmdb/HMDB0012219> ;
        dc:source           "HMDB" ;
        dcterms:identifier  "HMDB0012219" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2436_r139680> , <http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/cf41a> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:74684> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/142759> ;
        wp:bdbHmdb          <https://identifiers.org/hmdb/HMDB0012219> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/PQPXZWUZIOASKS-UHFFFAOYSA-N> ;
        wp:bdbKeggCompound  <https://identifiers.org/kegg.compound/C17755> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID162602> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q27144822> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2436_r139680/DataNode/edc51> ;
        foaf:page           <http://www.hmdb.ca/metabolites/HMDB0012219> .

<https://identifiers.org/pubmed/24409201>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "24409201" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2436_r139680> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/24409201> .

<http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/fb2de>
        rdf:type          wp:Conversion , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2436_r139680> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2436_r139680/Interaction/fb2de> ;
        wp:participants   <https://identifiers.org/hmdb/HMDB0001253> , <https://identifiers.org/hmdb/HMDB0001430> ;
        wp:source         <https://identifiers.org/hmdb/HMDB0001430> ;
        wp:target         <https://identifiers.org/hmdb/HMDB0001253> .

<https://identifiers.org/chebi/CHEBI:26523>
        rdf:type            wp:DataNode , wp:Metabolite ;
        rdfs:label          "ROS" ;
        dc:identifier       <https://identifiers.org/chebi/CHEBI:26523> ;
        dc:source           "ChEBI" ;
        dcterms:identifier  "CHEBI:26523" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2436_r139680> , <http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/ed31f> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:26523> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q424361> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2436_r139680/DataNode/c6a9b> ;
        foaf:page           <https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:26523> .

<https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=svg&pwTitle=Pathway:WP2436&oldid=139680>
        rdf:type        foaf:Image ;
        dcterms:format  "image/svg+xml" .

<http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/ac472>
        rdf:type          wp:Catalysis , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2436_r139680> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2436_r139680/Interaction/ac472> ;
        wp:participants   <https://identifiers.org/ncbigene/7299> , <http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/df957> ;
        wp:source         <https://identifiers.org/ncbigene/7299> ;
        wp:target         <http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/df957> .

<http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/a8d6e>
        rdf:type          wp:Catalysis , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2436_r139680> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2436_r139680/Interaction/a8d6e> ;
        wp:participants   <http://rdf.wikipathways.org/Pathway/WP2436_r139680/Complex/f0e09> , <http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/d3e94> ;
        wp:source         <http://rdf.wikipathways.org/Pathway/WP2436_r139680/Complex/f0e09> ;
        wp:target         <http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/d3e94> .

<http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/cfd80>
        rdf:type          wp:Conversion , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2436_r139680> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2436_r139680/Interaction/cfd80> ;
        wp:participants   <https://identifiers.org/hmdb/HMDB0000118> , <https://identifiers.org/chebi/CHEBI:41941> ;
        wp:source         <https://identifiers.org/chebi/CHEBI:41941> ;
        wp:target         <https://identifiers.org/hmdb/HMDB0000118> .

<http://rdf.wikipathways.org/Pathway/WP2436_r139680/ComplexBinding/af0ea>
        rdf:type          wp:ComplexBinding , wp:Binding , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2436_r139680> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2436_r139680/Group/af0ea> ;
        wp:participants   <https://identifiers.org/ncbigene/5568> , <https://identifiers.org/ncbigene/5567> , <https://identifiers.org/ncbigene/5566> , <http://rdf.wikipathways.org/Pathway/WP2436_r139680/Complex/af0ea> .

<https://identifiers.org/ncbigene/4129>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "MAOB" ;
        dc:identifier       <https://identifiers.org/ncbigene/4129> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "4129" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2436_r139680> , <http://rdf.wikipathways.org/Pathway/WP2436_r139680/Complex/f0e09> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000069535> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/4129> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/MAOB> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/P27338> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2436_r139680/DataNode/f4f6e> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P27338> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/4129> .

<http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/e9793>
        rdf:type          wp:Catalysis , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2436_r139680> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2436_r139680/Interaction/e9793> ;
        wp:participants   <https://identifiers.org/ncbigene/1728> , <http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/e306e> ;
        wp:source         <https://identifiers.org/ncbigene/1728> ;
        wp:target         <http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/e306e> .

<https://identifiers.org/ncbigene/6647>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "SOD1" ;
        dc:identifier       <https://identifiers.org/ncbigene/6647> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "6647" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2436_r139680> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000142168> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/6647> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/SOD1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/V9HWC9> , <https://identifiers.org/uniprot/H7BYH4> , <https://identifiers.org/uniprot/P00441> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2436_r139680/DataNode/c2161> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P00441> , <http://purl.uniprot.org/uniprot/V9HWC9> , <http://purl.uniprot.org/uniprot/H7BYH4> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/6647> .

<https://identifiers.org/hmdb/HMDB0003125>
        rdf:type            wp:Metabolite , wp:DataNode ;
        rdfs:label          "H₂O₂" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/MHAJPDPJQMAIIY-UHFFFAOYSA-N> ;
        dc:identifier       <https://identifiers.org/hmdb/HMDB0003125> ;
        dc:source           "HMDB" ;
        dcterms:identifier  "HMDB0003125" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/ded6b> , <http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/ed31f> , <https://identifiers.org/wikipathways/WP2436_r139680> , <http://rdf.wikipathways.org/Pathway/WP2436_r139680/WP/Interaction/b9f7e> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:16240> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/763> ;
        wp:bdbHmdb          <https://identifiers.org/hmdb/HMDB0003125> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/MHAJPDPJQMAIIY-UHFFFAOYSA-N> ;
        wp:bdbKeggCompound  <https://identifiers.org/kegg.compound/C00027> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID784> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q171877> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2436_r139680/DataNode/f4c52> ;
        foaf:page           <http://www.hmdb.ca/metabolites/HMDB0003125> .
