@prefix biopax:  <http://www.biopax.org/release/biopax-level3.owl#> .
@prefix cito:    <http://purl.org/spar/cito/> .
@prefix dc:      <http://purl.org/dc/elements/1.1/> .
@prefix dcterms: <http://purl.org/dc/terms/> .
@prefix foaf:    <http://xmlns.com/foaf/0.1/> .
@prefix freq:    <http://purl.org/cld/freq/> .
@prefix gpml:    <http://vocabularies.wikipathways.org/gpml#> .
@prefix obo:     <http://purl.obolibrary.org/obo/> .
@prefix owl:     <http://www.w3.org/2002/07/owl#> .
@prefix pav:     <http://purl.org/pav/> .
@prefix prov:    <http://www.w3.org/ns/prov#> .
@prefix rdf:     <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix rdfs:    <http://www.w3.org/2000/01/rdf-schema#> .
@prefix skos:    <http://www.w3.org/2004/02/skos/core#> .
@prefix void:    <http://rdfs.org/ns/void#> .
@prefix wp:      <http://vocabularies.wikipathways.org/wp#> .
@prefix wprdf:   <http://rdf.wikipathways.org/> .
@prefix xsd:     <http://www.w3.org/2001/XMLSchema#> .

<https://identifiers.org/ncbigene/171558>
        rdf:type            wp:DataNode , wp:Rna ;
        rdfs:label          "PTCRA" ;
        dc:identifier       <https://identifiers.org/ncbigene/171558> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "171558" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP61_r137144> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000171611> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/171558> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/PTCRA> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q6ISU1> , <https://identifiers.org/uniprot/A0A087WTE9> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP61_r137144/DataNode/bf9b3> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q6ISU1> , <http://purl.uniprot.org/uniprot/A0A087WTE9> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/171558> .

<https://identifiers.org/ncbigene/9541>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "CIR" ;
        dc:identifier       <https://identifiers.org/ncbigene/9541> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "9541" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP61_r137144/WP/Interaction/idc0a55e04> , <https://identifiers.org/wikipathways/WP61_r137144> , <http://rdf.wikipathways.org/Pathway/WP61_r137144/WP/Interaction/id1a79caf> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000138433> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/9541> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/CIR1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q86X95> , <https://identifiers.org/uniprot/H3BLY3> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP61_r137144/DataNode/cfc7e> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q86X95> , <http://purl.uniprot.org/uniprot/H3BLY3> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/9541> .

<https://identifiers.org/ncbigene/83737>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "ITCH" ;
        dc:identifier       <https://identifiers.org/ncbigene/83737> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "83737" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP61_r137144> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000289720> , <https://identifiers.org/ensembl/ENSG00000078747> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/83737> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/ITCH> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A590UJ55> , <https://identifiers.org/uniprot/A0A8V8TKI4> , <https://identifiers.org/uniprot/A0A1W2PNZ8> , <https://identifiers.org/uniprot/Q96J02> , <https://identifiers.org/uniprot/A0A590UJQ1> , <https://identifiers.org/uniprot/A0A8V8TKK4> , <https://identifiers.org/uniprot/A0A590UK44> , <https://identifiers.org/uniprot/A0A590UIY0> , <https://identifiers.org/uniprot/A0A590UK95> , <https://identifiers.org/uniprot/A0A590UJW8> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP61_r137144/DataNode/c9652> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A590UK44> , <http://purl.uniprot.org/uniprot/A0A8V8TKI4> , <http://purl.uniprot.org/uniprot/A0A8V8TKK4> , <http://purl.uniprot.org/uniprot/A0A590UIY0> , <http://purl.uniprot.org/uniprot/A0A590UJQ1> , <http://purl.uniprot.org/uniprot/Q96J02> , <http://purl.uniprot.org/uniprot/A0A590UK95> , <http://purl.uniprot.org/uniprot/A0A590UJW8> , <http://purl.uniprot.org/uniprot/A0A590UJ55> , <http://purl.uniprot.org/uniprot/A0A1W2PNZ8> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/83737> .

<http://rdf.wikipathways.org/Pathway/WP61_r137144/WP/Interaction/id54ed83a>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP61_r137144> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP61_r137144/Interaction/id54ed83a> ;
        wp:participants   <https://identifiers.org/ncbigene/22938> , <https://identifiers.org/ncbigene/4100> ;
        wp:source         <https://identifiers.org/ncbigene/4100> ;
        wp:target         <https://identifiers.org/ncbigene/22938> .

<http://rdf.wikipathways.org/Pathway/WP61_r137144/WP/Interaction/iddf54d7b4>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP61_r137144> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP61_r137144/Interaction/iddf54d7b4> ;
        wp:participants   <https://identifiers.org/ncbigene/2273> , <https://identifiers.org/ncbigene/6015> ;
        wp:source         <https://identifiers.org/ncbigene/6015> ;
        wp:target         <https://identifiers.org/ncbigene/2273> .

<https://identifiers.org/ncbigene/4855>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "NOTCH4" ;
        dc:identifier       <https://identifiers.org/ncbigene/4855> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "4855" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP61_r137144> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000204301> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/4855> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/NOTCH4> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A1U9X983> , <https://identifiers.org/uniprot/Q99466> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP61_r137144/DataNode/b795e> , <http://rdf.wikipathways.org/Pathway/WP61_r137144/DataNode/aac26> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q99466> , <http://purl.uniprot.org/uniprot/A0A1U9X983> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/4855> .

<https://identifiers.org/ncbigene/6500>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "SKP1" ;
        dc:identifier       <https://identifiers.org/ncbigene/6500> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "6500" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP61_r137144> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000113558> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/6500> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/SKP1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/E5RGM4> , <https://identifiers.org/uniprot/E5RHM3> , <https://identifiers.org/uniprot/P63208> , <https://identifiers.org/uniprot/E5RGM3> , <https://identifiers.org/uniprot/F8W8N3> , <https://identifiers.org/uniprot/E7ERH2> , <https://identifiers.org/uniprot/E5RJR5> , <https://identifiers.org/uniprot/E5RK33> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP61_r137144/DataNode/c1c9b> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/E5RGM4> , <http://purl.uniprot.org/uniprot/P63208> , <http://purl.uniprot.org/uniprot/E7ERH2> , <http://purl.uniprot.org/uniprot/E5RGM3> , <http://purl.uniprot.org/uniprot/E5RHM3> , <http://purl.uniprot.org/uniprot/E5RJR5> , <http://purl.uniprot.org/uniprot/F8W8N3> , <http://purl.uniprot.org/uniprot/E5RK33> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/6500> .

<https://identifiers.org/ncbigene/207>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "AKT1" ;
        dc:identifier       <https://identifiers.org/ncbigene/207> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "207" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP61_r137144/WP/Interaction/edbee> , <https://identifiers.org/wikipathways/WP61_r137144> , <http://rdf.wikipathways.org/Pathway/WP61_r137144/WP/Interaction/fce7c> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000142208> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/207> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/AKT1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/P31749> , <https://identifiers.org/uniprot/A0A804HJM6> , <https://identifiers.org/uniprot/B0LPE5> , <https://identifiers.org/uniprot/G3V2I6> , <https://identifiers.org/uniprot/A0A087WY56> , <https://identifiers.org/uniprot/G3V3X1> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP61_r137144/DataNode/a95ef> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/G3V2I6> , <http://purl.uniprot.org/uniprot/B0LPE5> , <http://purl.uniprot.org/uniprot/A0A804HJM6> , <http://purl.uniprot.org/uniprot/A0A087WY56> , <http://purl.uniprot.org/uniprot/P31749> , <http://purl.uniprot.org/uniprot/G3V3X1> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/207> .

<https://identifiers.org/ncbigene/7088>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "TLE1" ;
        dc:identifier       <https://identifiers.org/ncbigene/7088> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "7088" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP61_r137144> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000196781> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/7088> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/TLE1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A669KBB1> , <https://identifiers.org/uniprot/Q04724> , <https://identifiers.org/uniprot/A0A669KBK8> , <https://identifiers.org/uniprot/Q5T3G3> , <https://identifiers.org/uniprot/A0A669KAE5> , <https://identifiers.org/uniprot/Q5T3G2> , <https://identifiers.org/uniprot/F6T2C8> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP61_r137144/DataNode/ecb27> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A669KBK8> , <http://purl.uniprot.org/uniprot/Q04724> , <http://purl.uniprot.org/uniprot/Q5T3G3> , <http://purl.uniprot.org/uniprot/A0A669KBB1> , <http://purl.uniprot.org/uniprot/Q5T3G2> , <http://purl.uniprot.org/uniprot/A0A669KAE5> , <http://purl.uniprot.org/uniprot/F6T2C8> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/7088> .

<https://identifiers.org/ncbigene/55502>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "HES6" ;
        dc:identifier       <https://identifiers.org/ncbigene/55502> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "55502" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP61_r137144> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000144485> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/55502> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/HES6> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/B9A070> , <https://identifiers.org/uniprot/Q96HZ4> , <https://identifiers.org/uniprot/C9JF41> , <https://identifiers.org/uniprot/H7C1R4> , <https://identifiers.org/uniprot/B8ZZP9> , <https://identifiers.org/uniprot/H7C020> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP61_r137144/DataNode/f85b5> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q96HZ4> , <http://purl.uniprot.org/uniprot/H7C1R4> , <http://purl.uniprot.org/uniprot/B8ZZP9> , <http://purl.uniprot.org/uniprot/H7C020> , <http://purl.uniprot.org/uniprot/B9A070> , <http://purl.uniprot.org/uniprot/C9JF41> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/55502> .

<https://identifiers.org/ncbigene/6774>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "STAT3" ;
        dc:identifier       <https://identifiers.org/ncbigene/6774> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "6774" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP61_r137144/WP/Interaction/d574e> , <http://rdf.wikipathways.org/Pathway/WP61_r137144/WP/Interaction/idcb67675b> , <http://rdf.wikipathways.org/Pathway/WP61_r137144/WP/Interaction/id49b25a85> , <https://identifiers.org/wikipathways/WP61_r137144> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000168610> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/6774> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/STAT3> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A7I2V4F6> , <https://identifiers.org/uniprot/A0A7I2YQI1> , <https://identifiers.org/uniprot/A0A7I2V2T1> , <https://identifiers.org/uniprot/A0A7I2V3V0> , <https://identifiers.org/uniprot/A0A7I2V4R2> , <https://identifiers.org/uniprot/A0A7I2V395> , <https://identifiers.org/uniprot/A0A7I2V5N9> , <https://identifiers.org/uniprot/P40763> , <https://identifiers.org/uniprot/A0A7I2V444> , <https://identifiers.org/uniprot/A0A7I2V4C8> , <https://identifiers.org/uniprot/A0A7I2V4R3> , <https://identifiers.org/uniprot/A0A7I2V552> , <https://identifiers.org/uniprot/A0A7I2YQR5> , <https://identifiers.org/uniprot/A0A7I2V2G1> , <https://identifiers.org/uniprot/G8JLH9> , <https://identifiers.org/uniprot/A0A7I2YQD2> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP61_r137144/DataNode/d4e80> , <http://rdf.wikipathways.org/Pathway/WP61_r137144/DataNode/fc7a6> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A7I2YQI1> , <http://purl.uniprot.org/uniprot/P40763> , <http://purl.uniprot.org/uniprot/A0A7I2V5N9> , <http://purl.uniprot.org/uniprot/G8JLH9> , <http://purl.uniprot.org/uniprot/A0A7I2V4R3> , <http://purl.uniprot.org/uniprot/A0A7I2V3V0> , <http://purl.uniprot.org/uniprot/A0A7I2V4F6> , <http://purl.uniprot.org/uniprot/A0A7I2V444> , <http://purl.uniprot.org/uniprot/A0A7I2V395> , <http://purl.uniprot.org/uniprot/A0A7I2V2T1> , <http://purl.uniprot.org/uniprot/A0A7I2V4R2> , <http://purl.uniprot.org/uniprot/A0A7I2YQR5> , <http://purl.uniprot.org/uniprot/A0A7I2V552> , <http://purl.uniprot.org/uniprot/A0A7I2V4C8> , <http://purl.uniprot.org/uniprot/A0A7I2V2G1> , <http://purl.uniprot.org/uniprot/A0A7I2YQD2> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/6774> .

<https://identifiers.org/ncbigene/23493>
        rdf:type            wp:DataNode , wp:Protein , wp:Rna ;
        rdfs:label          "HEY2" ;
        dc:identifier       <https://identifiers.org/ncbigene/23493> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "23493" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP61_r137144> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000135547> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/23493> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/HEY2> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q9UBP5> , <https://identifiers.org/uniprot/Q5TF93> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP61_r137144/DataNode/c80a1> , <http://rdf.wikipathways.org/Pathway/WP61_r137144/DataNode/b1b6c> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q5TF93> , <http://purl.uniprot.org/uniprot/Q9UBP5> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/23493> .

<https://identifiers.org/ncbigene/4790>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "NFKB1" ;
        dc:identifier       <https://identifiers.org/ncbigene/4790> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "4790" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP61_r137144> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000109320> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/4790> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/NFKB1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/D6RH30> , <https://identifiers.org/uniprot/A0A8V8TLB2> , <https://identifiers.org/uniprot/D6RC45> , <https://identifiers.org/uniprot/P19838> , <https://identifiers.org/uniprot/A0A494C1E9> , <https://identifiers.org/uniprot/A0A494C157> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP61_r137144/DataNode/b9c51> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/D6RH30> , <http://purl.uniprot.org/uniprot/P19838> , <http://purl.uniprot.org/uniprot/A0A8V8TLB2> , <http://purl.uniprot.org/uniprot/A0A494C157> , <http://purl.uniprot.org/uniprot/D6RC45> , <http://purl.uniprot.org/uniprot/A0A494C1E9> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/4790> .

<https://identifiers.org/ncbigene/9794>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "MAML1" ;
        dc:identifier       <https://identifiers.org/ncbigene/9794> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "9794" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP61_r137144/WP/Interaction/bc46d> , <https://identifiers.org/wikipathways/WP61_r137144> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000161021> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/9794> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/MAML1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q92585> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP61_r137144/DataNode/e354b> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q92585> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/9794> .

<http://rdf.wikipathways.org/Pathway/WP61_r137144/WP/Interaction/a4a6f>
        rdf:type          wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP61_r137144> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP61_r137144/Interaction/a4a6f> .

<https://identifiers.org/ncbigene/9612>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "NCOR2" ;
        dc:identifier       <https://identifiers.org/ncbigene/9612> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "9612" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP61_r137144> , <http://rdf.wikipathways.org/Pathway/WP61_r137144/WP/Interaction/ida736b519> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000196498> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/9612> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/NCOR2> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/C9JNV9> , <https://identifiers.org/uniprot/C9J330> , <https://identifiers.org/uniprot/H7C1J7> , <https://identifiers.org/uniprot/H7C0P3> , <https://identifiers.org/uniprot/Q9Y618> , <https://identifiers.org/uniprot/H7BZU2> , <https://identifiers.org/uniprot/H0YGK8> , <https://identifiers.org/uniprot/H7C184> , <https://identifiers.org/uniprot/H7C1Y3> , <https://identifiers.org/uniprot/C9JE98> , <https://identifiers.org/uniprot/H7C2R5> , <https://identifiers.org/uniprot/C9J0Q5> , <https://identifiers.org/uniprot/C9JQE8> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP61_r137144/DataNode/f897b> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/C9JNV9> , <http://purl.uniprot.org/uniprot/Q9Y618> , <http://purl.uniprot.org/uniprot/H7BZU2> , <http://purl.uniprot.org/uniprot/C9JE98> , <http://purl.uniprot.org/uniprot/H7C1Y3> , <http://purl.uniprot.org/uniprot/H7C2R5> , <http://purl.uniprot.org/uniprot/C9J330> , <http://purl.uniprot.org/uniprot/C9J0Q5> , <http://purl.uniprot.org/uniprot/C9JQE8> , <http://purl.uniprot.org/uniprot/H0YGK8> , <http://purl.uniprot.org/uniprot/H7C184> , <http://purl.uniprot.org/uniprot/H7C0P3> , <http://purl.uniprot.org/uniprot/H7C1J7> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/9612> .

<https://identifiers.org/ncbigene/5296>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "PIK3R2" ;
        dc:identifier       <https://identifiers.org/ncbigene/5296> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "5296" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP61_r137144> , <http://rdf.wikipathways.org/Pathway/WP61_r137144/WP/Interaction/fce7c> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000105647> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/5296> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/PIK3R2> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/V9GYJ4> , <https://identifiers.org/uniprot/A0A7I2U3A3> , <https://identifiers.org/uniprot/O00459> , <https://identifiers.org/uniprot/A0A087X257> , <https://identifiers.org/uniprot/E9PFP1> , <https://identifiers.org/uniprot/A0A5F9ZHY3> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP61_r137144/DataNode/aef70> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A5F9ZHY3> , <http://purl.uniprot.org/uniprot/A0A7I2U3A3> , <http://purl.uniprot.org/uniprot/O00459> , <http://purl.uniprot.org/uniprot/V9GYJ4> , <http://purl.uniprot.org/uniprot/E9PFP1> , <http://purl.uniprot.org/uniprot/A0A087X257> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/5296> .

<http://rdf.wikipathways.org/Pathway/WP61_r137144/WP/Interaction/idc0a55e04>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP61_r137144> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP61_r137144/Interaction/idc0a55e04> ;
        wp:participants   <https://identifiers.org/ncbigene/9541> , <https://identifiers.org/ncbigene/3066> ;
        wp:source         <https://identifiers.org/ncbigene/3066> ;
        wp:target         <https://identifiers.org/ncbigene/9541> .

<https://identifiers.org/ncbigene/3714>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "JAG2" ;
        dc:identifier       <https://identifiers.org/ncbigene/3714> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "3714" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP61_r137144> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000184916> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/3714> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/JAG2> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q9Y219> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP61_r137144/DataNode/d302b> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q9Y219> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/3714> .

<https://identifiers.org/pubmed/20067622>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "20067622" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP61_r137144> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/20067622> .

<http://rdf.wikipathways.org/Pathway/WP61_r137144/WP/Interaction/id4291f8d7>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP61_r137144> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP61_r137144/Interaction/id4291f8d7> ;
        wp:participants   <https://identifiers.org/ncbigene/5295> , <https://identifiers.org/ncbigene/3932> ;
        wp:source         <https://identifiers.org/ncbigene/3932> ;
        wp:target         <https://identifiers.org/ncbigene/5295> .

<https://identifiers.org/ncbigene/4854>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "NOTCH3" ;
        dc:identifier       <https://identifiers.org/ncbigene/4854> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "4854" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP61_r137144> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000074181> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/4854> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/NOTCH3> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/M0R3C9> , <https://identifiers.org/uniprot/M0QX38> , <https://identifiers.org/uniprot/M0QZN3> , <https://identifiers.org/uniprot/Q9UM47> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP61_r137144/DataNode/dd792> , <http://rdf.wikipathways.org/Pathway/WP61_r137144/DataNode/d25ab> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/M0QZN3> , <http://purl.uniprot.org/uniprot/M0QX38> , <http://purl.uniprot.org/uniprot/M0R3C9> , <http://purl.uniprot.org/uniprot/Q9UM47> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/4854> .

<https://doi.org/10.1016%2Fj.compbiomed.2014.12.003>
        rdf:type            wp:PublicationReference ;
        dc:source           "DOI" ;
        dcterms:identifier  "10.1016/j.compbiomed.2014.12.003" ;
        cito:cites          <https://identifiers.org/wikipathways/WP61> .

<http://rdf.wikipathways.org/Pathway/WP61_r137144/WP/Interaction/idcb67675b>
        rdf:type          wp:TranscriptionTranslation , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP61_r137144> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP61_r137144/Interaction/idcb67675b> ;
        wp:participants   <https://identifiers.org/ncbigene/3091> , <https://identifiers.org/ncbigene/6774> ;
        wp:source         <https://identifiers.org/ncbigene/6774> ;
        wp:target         <https://identifiers.org/ncbigene/3091> .

<https://identifiers.org/ncbigene/595>
        rdf:type            wp:Rna , wp:DataNode ;
        rdfs:label          "CCND1" ;
        dc:identifier       <https://identifiers.org/ncbigene/595> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "595" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP61_r137144> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000110092> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/595> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/CCND1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/F5H437> , <https://identifiers.org/uniprot/Q6FI00> , <https://identifiers.org/uniprot/P24385> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP61_r137144/DataNode/e5d43> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P24385> , <http://purl.uniprot.org/uniprot/Q6FI00> , <http://purl.uniprot.org/uniprot/F5H437> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/595> .

<https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=svg&pwTitle=Pathway:WP61&oldid=137144>
        rdf:type        foaf:Image ;
        dcterms:format  "image/svg+xml" .

<https://identifiers.org/ncbigene/23385>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "NCSTN" ;
        dc:identifier       <https://identifiers.org/ncbigene/23385> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "23385" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP61_r137144> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000162736> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/23385> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/NCSTN> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A8V8TNV7> , <https://identifiers.org/uniprot/A0A8V8TQ61> , <https://identifiers.org/uniprot/Q92542> , <https://identifiers.org/uniprot/A0A8V8TPR8> , <https://identifiers.org/uniprot/A0A2U3TZL9> , <https://identifiers.org/uniprot/Q5T210> , <https://identifiers.org/uniprot/H0Y3Z4> , <https://identifiers.org/uniprot/A0A8V8TNU8> , <https://identifiers.org/uniprot/A0A8V8TNI3> , <https://identifiers.org/uniprot/A0A2R8YE20> , <https://identifiers.org/uniprot/Q5T209> , <https://identifiers.org/uniprot/A0A8V8TNC8> , <https://identifiers.org/uniprot/Q5T211> , <https://identifiers.org/uniprot/Q5T205> , <https://identifiers.org/uniprot/A0A2R8YCK1> , <https://identifiers.org/uniprot/A0A8V8TNI9> , <https://identifiers.org/uniprot/A0A8V8TPQ8> , <https://identifiers.org/uniprot/H0Y6T7> , <https://identifiers.org/uniprot/A0A8V8TNV3> , <https://identifiers.org/uniprot/A0A8V8TQ51> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP61_r137144/DataNode/abacd> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A8V8TQ61> , <http://purl.uniprot.org/uniprot/H0Y6T7> , <http://purl.uniprot.org/uniprot/A0A2R8YE20> , <http://purl.uniprot.org/uniprot/A0A8V8TNC8> , <http://purl.uniprot.org/uniprot/Q5T211> , <http://purl.uniprot.org/uniprot/Q5T209> , <http://purl.uniprot.org/uniprot/A0A8V8TNV3> , <http://purl.uniprot.org/uniprot/A0A8V8TNV7> , <http://purl.uniprot.org/uniprot/A0A8V8TNI3> , <http://purl.uniprot.org/uniprot/A0A2R8YCK1> , <http://purl.uniprot.org/uniprot/A0A8V8TQ51> , <http://purl.uniprot.org/uniprot/A0A8V8TPR8> , <http://purl.uniprot.org/uniprot/Q92542> , <http://purl.uniprot.org/uniprot/Q5T205> , <http://purl.uniprot.org/uniprot/A0A8V8TNU8> , <http://purl.uniprot.org/uniprot/A0A2U3TZL9> , <http://purl.uniprot.org/uniprot/Q5T210> , <http://purl.uniprot.org/uniprot/H0Y3Z4> , <http://purl.uniprot.org/uniprot/A0A8V8TPQ8> , <http://purl.uniprot.org/uniprot/A0A8V8TNI9> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/23385> .

<https://identifiers.org/ncbigene/83464>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "APH1B" ;
        dc:identifier       <https://identifiers.org/ncbigene/83464> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "83464" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP61_r137144> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000138613> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/83464> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/APH1B> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/H0YM95> , <https://identifiers.org/uniprot/H0YLT0> , <https://identifiers.org/uniprot/Q4R1J8> , <https://identifiers.org/uniprot/Q8WW43> , <https://identifiers.org/uniprot/H0YKZ9> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP61_r137144/DataNode/f041f> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q8WW43> , <http://purl.uniprot.org/uniprot/H0YM95> , <http://purl.uniprot.org/uniprot/H0YKZ9> , <http://purl.uniprot.org/uniprot/H0YLT0> , <http://purl.uniprot.org/uniprot/Q4R1J8> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/83464> .

<http://rdf.wikipathways.org/Pathway/WP61_r137144/WP/Interaction/id49b25a85>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP61_r137144> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP61_r137144/Interaction/id49b25a85> ;
        wp:participants   <https://identifiers.org/ncbigene/6774> ;
        wp:source         <https://identifiers.org/ncbigene/6774> ;
        wp:target         <https://identifiers.org/ncbigene/6774> .

<https://identifiers.org/ncbigene/9253>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "NUMBL" ;
        dc:identifier       <https://identifiers.org/ncbigene/9253> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "9253" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP61_r137144> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000105245> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/9253> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/NUMBL> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/M0QYC2> , <https://identifiers.org/uniprot/M0QZV7> , <https://identifiers.org/uniprot/M0QXQ4> , <https://identifiers.org/uniprot/M0R0Q4> , <https://identifiers.org/uniprot/Q9Y6R0> , <https://identifiers.org/uniprot/A0A0C4DGH3> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP61_r137144/DataNode/d180c> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q9Y6R0> , <http://purl.uniprot.org/uniprot/M0R0Q4> , <http://purl.uniprot.org/uniprot/A0A0C4DGH3> , <http://purl.uniprot.org/uniprot/M0QYC2> , <http://purl.uniprot.org/uniprot/M0QXQ4> , <http://purl.uniprot.org/uniprot/M0QZV7> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/9253> .

<http://rdf.wikipathways.org/Pathway/WP61_r137144/WP/Interaction/id4f06e241>
        rdf:type          wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP61_r137144> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP61_r137144/Interaction/id4f06e241> .

<https://identifiers.org/ncbigene/3091>
        rdf:type            wp:DataNode , wp:Rna ;
        rdfs:label          "HIF1A" ;
        dc:identifier       <https://identifiers.org/ncbigene/3091> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "3091" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP61_r137144/WP/Interaction/idcb67675b> , <https://identifiers.org/wikipathways/WP61_r137144> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000100644> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/3091> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/HIF1A> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/D0VY79> , <https://identifiers.org/uniprot/Q16665> , <https://identifiers.org/uniprot/A8MYV6> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP61_r137144/DataNode/c0a62> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q16665> , <http://purl.uniprot.org/uniprot/A8MYV6> , <http://purl.uniprot.org/uniprot/D0VY79> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/3091> .

<https://identifiers.org/ncbigene/9611>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "NCOR1" ;
        dc:identifier       <https://identifiers.org/ncbigene/9611> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "9611" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP61_r137144> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000141027> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/9611> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/NCOR1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/J3KS29> , <https://identifiers.org/uniprot/O75376> , <https://identifiers.org/uniprot/A0A024RD47> , <https://identifiers.org/uniprot/E7EVU5> , <https://identifiers.org/uniprot/J3KT44> , <https://identifiers.org/uniprot/J3QKP0> , <https://identifiers.org/uniprot/E7EVK1> , <https://identifiers.org/uniprot/A0A994J5B8> , <https://identifiers.org/uniprot/H0Y459> , <https://identifiers.org/uniprot/E7EW50> , <https://identifiers.org/uniprot/C9JAP0> , <https://identifiers.org/uniprot/S4R380> , <https://identifiers.org/uniprot/J3KRE4> , <https://identifiers.org/uniprot/J3KS51> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP61_r137144/DataNode/f408e> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/H0Y459> , <http://purl.uniprot.org/uniprot/O75376> , <http://purl.uniprot.org/uniprot/E7EVK1> , <http://purl.uniprot.org/uniprot/A0A024RD47> , <http://purl.uniprot.org/uniprot/J3KS51> , <http://purl.uniprot.org/uniprot/A0A994J5B8> , <http://purl.uniprot.org/uniprot/J3KT44> , <http://purl.uniprot.org/uniprot/J3QKP0> , <http://purl.uniprot.org/uniprot/J3KRE4> , <http://purl.uniprot.org/uniprot/E7EW50> , <http://purl.uniprot.org/uniprot/C9JAP0> , <http://purl.uniprot.org/uniprot/E7EVU5> , <http://purl.uniprot.org/uniprot/J3KS29> , <http://purl.uniprot.org/uniprot/S4R380> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/9611> .

<https://identifiers.org/ncbigene/5295>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "PIK3R1" ;
        dc:identifier       <https://identifiers.org/ncbigene/5295> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "5295" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP61_r137144> , <http://rdf.wikipathways.org/Pathway/WP61_r137144/WP/Interaction/id4291f8d7> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000145675> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/5295> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/PIK3R1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/E5RJY0> , <https://identifiers.org/uniprot/H0YB27> , <https://identifiers.org/uniprot/A0A8V8TME9> , <https://identifiers.org/uniprot/P27986> , <https://identifiers.org/uniprot/A0A8V8TL14> , <https://identifiers.org/uniprot/A0A8V8TL31> , <https://identifiers.org/uniprot/E5RGI8> , <https://identifiers.org/uniprot/A0A8V8TLE6> , <https://identifiers.org/uniprot/A0A8V8TLF1> , <https://identifiers.org/uniprot/B3KWZ7> , <https://identifiers.org/uniprot/E5RHI0> , <https://identifiers.org/uniprot/E5RK66> , <https://identifiers.org/uniprot/A0A8V8TMF4> , <https://identifiers.org/uniprot/A0A8V8TLF7> , <https://identifiers.org/uniprot/A0A8V8TMF9> , <https://identifiers.org/uniprot/A0A8V8TL10> , <https://identifiers.org/uniprot/H0YBC2> , <https://identifiers.org/uniprot/A0A2X0SFG1> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP61_r137144/DataNode/d85a7> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A8V8TMF9> , <http://purl.uniprot.org/uniprot/A0A8V8TME9> , <http://purl.uniprot.org/uniprot/A0A8V8TL14> , <http://purl.uniprot.org/uniprot/A0A8V8TL10> , <http://purl.uniprot.org/uniprot/P27986> , <http://purl.uniprot.org/uniprot/A0A8V8TL31> , <http://purl.uniprot.org/uniprot/H0YBC2> , <http://purl.uniprot.org/uniprot/E5RGI8> , <http://purl.uniprot.org/uniprot/A0A8V8TLE6> , <http://purl.uniprot.org/uniprot/A0A8V8TLF7> , <http://purl.uniprot.org/uniprot/B3KWZ7> , <http://purl.uniprot.org/uniprot/E5RHI0> , <http://purl.uniprot.org/uniprot/A0A2X0SFG1> , <http://purl.uniprot.org/uniprot/H0YB27> , <http://purl.uniprot.org/uniprot/A0A8V8TMF4> , <http://purl.uniprot.org/uniprot/A0A8V8TLF1> , <http://purl.uniprot.org/uniprot/E5RK66> , <http://purl.uniprot.org/uniprot/E5RJY0> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/5295> .

<http://rdf.wikipathways.org/Pathway/WP61_r137144/WP/Interaction/c5b88>
        rdf:type          wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP61_r137144> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP61_r137144/Interaction/c5b88> .

<https://identifiers.org/ncbigene/182>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "JAG1" ;
        dc:identifier       <https://identifiers.org/ncbigene/182> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "182" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP61_r137144> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000101384> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/182> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/JAG1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/P78504> , <https://identifiers.org/uniprot/A0A087X1E8> , <https://identifiers.org/uniprot/A0A087WXH5> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP61_r137144/DataNode/c9bc0> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P78504> , <http://purl.uniprot.org/uniprot/A0A087X1E8> , <http://purl.uniprot.org/uniprot/A0A087WXH5> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/182> .

<https://identifiers.org/ncbigene/4853>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "NOTCH2" ;
        dc:identifier       <https://identifiers.org/ncbigene/4853> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "4853" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP61_r137144> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000134250> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/4853> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/NOTCH2> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A494C1H8> , <https://identifiers.org/uniprot/A0A494C1F1> , <https://identifiers.org/uniprot/A0A494C1U9> , <https://identifiers.org/uniprot/Q04721> , <https://identifiers.org/uniprot/A0A1W2PQQ5> , <https://identifiers.org/uniprot/A0A494C049> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP61_r137144/DataNode/b2885> , <http://rdf.wikipathways.org/Pathway/WP61_r137144/DataNode/ea69e> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A1W2PQQ5> , <http://purl.uniprot.org/uniprot/A0A494C049> , <http://purl.uniprot.org/uniprot/Q04721> , <http://purl.uniprot.org/uniprot/A0A494C1F1> , <http://purl.uniprot.org/uniprot/A0A494C1U9> , <http://purl.uniprot.org/uniprot/A0A494C1H8> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/4853> .

<https://identifiers.org/ncbigene/55534>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "MAML3" ;
        dc:identifier       <https://identifiers.org/ncbigene/55534> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "55534" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP61_r137144> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000196782> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/55534> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/MAML3> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q96JK9> , <https://identifiers.org/uniprot/H0Y920> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP61_r137144/DataNode/b52cb> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/H0Y920> , <http://purl.uniprot.org/uniprot/Q96JK9> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/55534> .

<https://identifiers.org/ncbigene/4100>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "MAGEA1" ;
        dc:identifier       <https://identifiers.org/ncbigene/4100> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "4100" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP61_r137144> , <http://rdf.wikipathways.org/Pathway/WP61_r137144/WP/Interaction/id54ed83a> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000198681> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/4100> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/MAGEA1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/P43355> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP61_r137144/DataNode/f6904> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P43355> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/4100> .

obo:NCBITaxon_9606  obo:NCIT_C179773  "9606" .

<http://rdf.wikipathways.org/Pathway/WP61_r137144/WP/Interaction/bc46d>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP61_r137144> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP61_r137144/Interaction/bc46d> ;
        wp:participants   <https://identifiers.org/ncbigene/9794> , <https://identifiers.org/ncbigene/2033> ;
        wp:source         <https://identifiers.org/ncbigene/2033> ;
        wp:target         <https://identifiers.org/ncbigene/9794> .

<https://identifiers.org/wikipathways/WP61_r137144>
        rdf:type               skos:Collection , wp:Pathway ;
        dc:identifier          <https://identifiers.org/wikipathways/WP61> ;
        dc:source              "WikiPathways" ;
        dc:title               "Notch signaling"@en ;
        dcterms:description    "The Notch pathway is an evolutionally conserved signaling pathway which plays an important role in diverse developmental and physiological processes. These include cell-fate determination, tissue patterning and morphogenesis, cell differentiation, proliferation and cell death. The Notch pathway is named after the Drosophila mutants that showed irregular notches of missing tissue at the insect wing blade tips. The Notch gene was cloned in 1985. Proteins of the Notch families are single-pass transmembrane proteins that function both as cell surface receptors and nuclear transcriptional regulators. Four Notch receptors (Notch 1-4) have been identified in mammals. Mature Notch receptors are non-covalent heterodimers consisting of an extracellular subunit (NEC) and a transmembrane subunit (NTM). NEC possess multiple EGF-like repeats and three specialized Lin-Notch repeats (LNR) that forms a tight hydrophobic interaction with extracellular stump of NTM. This region masks an A disintegrin and metalloprotease (ADAM) cleavage site. The region where these two subunits interact is called the heterodimerization domain (HD). Notch ligands are also transmembrane proteins with multiple EGF-like repeats, a short cytoplasmic tail and a specialized delta-serrate-lag2 (DSL) domain at the N-terminus. There are five canonical Notch ligands i.e. Jagged (JAG1 and JAG2), Delta-like (DLL1, DLL3, DLL4) in mammals. Notch signaling activation occurs upon ligand-receptor binding, which are expressed on two adjacent cells. Ligand binding causes dissociation of NEC from NTM, unmasking the ADAM cleavage site. The NEC fragment is trans- endocytosed into the ligand expressing cells. The full-length receptor minus the NEC fragment is cleaved at the membrane by ADAM17 generating an intermediate, Notch extracellular truncation (NEXT). This is further cleaved by Î³-secretase that generates an active Notch intracellular fragment (NIC) or Notch intracellular domain (NICD). The Î³-secretase complex is composed of PSEN1, PSEN2, PSENEN, NCSTN and APH1 (A or B). Following these two cleavage steps, the NICD is released into the cytoplasm and translocates into the nucleus to regulate transcription of Notch target genes. Upon translocation into the nucleus, NICD binds to RBPJ which is a constitutive repressor of Notch signaling. RBPJ represses Notch target gene expression by recruiting a co-repressor complex, which includes NCOR1, NCOR2, SNW1, CIR, HDAC1, HDAC2, SPEN and FHL1 and SAP30. NICD binding to RBPJ replaces the co-repressor complex with a co-activator complex which includes MAML1-3, EP300 and SNW1. Primary Notch target genes include two families of transcriptional factors Hes, including HES1 and HES5 as well as Hey including HEY1 and HEY2. Other Notch target genes include CCND1, CDKN1A, GATA3 and PTCRA. CNTN1 acts as a functional ligand of Notch. This trans-extracellular interaction causes Î³-secretase-dependent nuclear translocation of the NICD. This signaling is involved in oligodendrocyte precursor cell differentiation and upregulation of myelin-related protein MAG. In addition to the canonical Notch pathway, there is increasing evidence showing RBPJ independent non-canonical pathways. been fully characterized. Physical interaction of NOTCH-1IC with LCK- PI3K may mediate non-nuclear cross-talk with AKT, leading to survival signaling. Notch stimulation through AKT pathway leads to down regulation of MYC expression. Activation of SRC/STAT3 pathway by Notch signaling is dependent on the expression of Notch effector HES1 transcription factor. The induction of HES1 enhanced SRC phosphorylation. This activated SRC kinase was found to be responsible for the enhanced phosphorylation of STAT3. The HES1 and HES5 proteins associate with and facilitate the complex formation between JAK2 and STAT3, thus promoting STAT3 phosphorylation and activation. The activated STAT3 translocates from the cytoplasm to the nucleus and induces transcriptional activation of target gene expression (including HIF1A).\n\nPlease access this pathway at [NetSlim](http://www.netpath.org/netslim/notch_pathway.html) database.\n\nIf you use this pathway, please cite following paper:\nKandasamy, K., Mohan, S. S., Raju, R., Keerthikumar, S., Kumar, G. S. S., Venugopal, A. K., Telikicherla, D., Navarro, J. D., Mathivanan, S., Pecquet, C., Gollapudi, S. K., Tattikota, S. G., Mohan, S., Padhukasahasram, H., Subbannayya, Y., Goel, R., Jacob, H. K. C., Zhong, J., Sekhar, R., Nanjappa, V., Balakrishnan, L., Subbaiah, R., Ramachandra, Y. L., Rahiman, B. A., Prasad, T. S. K., Lin, J., Houtman, J. C. D., Desiderio, S., Renauld, J., Constantinescu, S. N., Ohara, O., Hirano, T., Kubo, M., Singh, S., Khatri, P., Draghici, S., Bader, G. D., Sander, C., Leonard, W. J. and Pandey, A. (2010). NetPath: A public resource of curated signal transduction pathways. <i>Genome Biology</i>. 11:R3." ;
        dcterms:identifier     "WP61" ;
        dcterms:references     <https://identifiers.org/pubmed/20067622> ;
        cito:cites             <https://identifiers.org/pubmed/20067622> ;
        wp:isAbout             <http://rdf.wikipathways.org/Pathway/WP61_r137144> ;
        wp:ontologyTag         wp:Curation:ONTOX , obo:PW_0000204 , wp:Curation:AnalysisCollection ;
        wp:organism            obo:NCBITaxon_9606 ;
        wp:organismName        "Homo sapiens" ;
        wp:pathwayOntologyTag  obo:PW_0000204 ;
        foaf:img               <https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=svg&pwTitle=Pathway:WP61&oldid=137144> , <https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=png&pwTitle=Pathway:WP61&oldid=137144> ;
        foaf:page              <http://www.wikipathways.org/instance/WP61_r137144> .

<http://rdf.wikipathways.org/Pathway/WP61_r137144/WP/Interaction/edbee>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP61_r137144> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP61_r137144/Interaction/edbee> ;
        wp:participants   <https://identifiers.org/hgnc.symbol/MTOR> , <https://identifiers.org/ncbigene/207> ;
        wp:source         <https://identifiers.org/ncbigene/207> ;
        wp:target         <https://identifiers.org/hgnc.symbol/MTOR> .

<http://rdf.wikipathways.org/Pathway/WP61_r137144/WP/Interaction/e3e6d>
        rdf:type          wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP61_r137144> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP61_r137144/Interaction/e3e6d> ;
        wp:participants   <https://identifiers.org/ncbigene/28514> .

<http://rdf.wikipathways.org/Pathway/WP61_r137144/WP/Interaction/fce7c>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP61_r137144> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP61_r137144/Interaction/fce7c> ;
        wp:participants   <https://identifiers.org/ncbigene/207> , <https://identifiers.org/ncbigene/5296> ;
        wp:source         <https://identifiers.org/ncbigene/5296> ;
        wp:target         <https://identifiers.org/ncbigene/207> .

<https://identifiers.org/ncbigene/3932>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "LCK" ;
        dc:identifier       <https://identifiers.org/ncbigene/3932> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "3932" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP61_r137144> , <http://rdf.wikipathways.org/Pathway/WP61_r137144/WP/Interaction/id4291f8d7> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000182866> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/3932> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/LCK> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/E9PAP0> , <https://identifiers.org/uniprot/E9PJ92> , <https://identifiers.org/uniprot/P06239> , <https://identifiers.org/uniprot/A0A0S2Z3Y8> , <https://identifiers.org/uniprot/A0A0S2Z3T3> , <https://identifiers.org/uniprot/F8W6B9> , <https://identifiers.org/uniprot/A0A8V8TKX3> , <https://identifiers.org/uniprot/E9PQ10> , <https://identifiers.org/uniprot/E9PI33> , <https://identifiers.org/uniprot/E9PKQ8> , <https://identifiers.org/uniprot/A0A8V8TM09> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP61_r137144/DataNode/c59af> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/E9PAP0> , <http://purl.uniprot.org/uniprot/E9PKQ8> , <http://purl.uniprot.org/uniprot/A0A8V8TKX3> , <http://purl.uniprot.org/uniprot/P06239> , <http://purl.uniprot.org/uniprot/A0A0S2Z3Y8> , <http://purl.uniprot.org/uniprot/E9PI33> , <http://purl.uniprot.org/uniprot/A0A8V8TM09> , <http://purl.uniprot.org/uniprot/E9PJ92> , <http://purl.uniprot.org/uniprot/A0A0S2Z3T3> , <http://purl.uniprot.org/uniprot/F8W6B9> , <http://purl.uniprot.org/uniprot/E9PQ10> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/3932> .

<https://identifiers.org/ncbigene/8650>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "NUMB" ;
        dc:identifier       <https://identifiers.org/ncbigene/8650> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "8650" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP61_r137144> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000133961> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/8650> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/NUMB> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A024R684> , <https://identifiers.org/uniprot/G3V433> , <https://identifiers.org/uniprot/G3V3Z8> , <https://identifiers.org/uniprot/A0A024R681> , <https://identifiers.org/uniprot/G3V3R1> , <https://identifiers.org/uniprot/A0A024R6C4> , <https://identifiers.org/uniprot/G3V3M5> , <https://identifiers.org/uniprot/G3V4S6> , <https://identifiers.org/uniprot/A0A024R6F4> , <https://identifiers.org/uniprot/P49757> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP61_r137144/DataNode/c5c4d> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/G3V3Z8> , <http://purl.uniprot.org/uniprot/G3V4S6> , <http://purl.uniprot.org/uniprot/G3V3M5> , <http://purl.uniprot.org/uniprot/A0A024R684> , <http://purl.uniprot.org/uniprot/A0A024R681> , <http://purl.uniprot.org/uniprot/P49757> , <http://purl.uniprot.org/uniprot/A0A024R6C4> , <http://purl.uniprot.org/uniprot/G3V3R1> , <http://purl.uniprot.org/uniprot/G3V433> , <http://purl.uniprot.org/uniprot/A0A024R6F4> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/8650> .

<https://identifiers.org/wikipathways/WP61>
        pav:hasVersion  <https://identifiers.org/wikipathways/WP61_r137144> .

<https://identifiers.org/ncbigene/84441>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "MAML2" ;
        dc:identifier       <https://identifiers.org/ncbigene/84441> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "84441" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP61_r137144> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000184384> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/84441> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/MAML2> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q8IZL2> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP61_r137144/DataNode/f1f3c> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q8IZL2> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/84441> .

<http://rdf.wikipathways.org/Pathway/WP61_r137144/WP/Interaction/d574e>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP61_r137144> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP61_r137144/Interaction/d574e> ;
        wp:participants   <https://identifiers.org/ncbigene/6774> , <https://identifiers.org/ncbigene/6714> ;
        wp:source         <https://identifiers.org/ncbigene/6714> ;
        wp:target         <https://identifiers.org/ncbigene/6774> .

<https://identifiers.org/ncbigene/54567>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "DLL4" ;
        dc:identifier       <https://identifiers.org/ncbigene/54567> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "54567" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP61_r137144> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000128917> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/54567> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/DLL4> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q9NR61> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP61_r137144/DataNode/ced61> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q9NR61> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/54567> .

<http://rdf.wikipathways.org/Pathway/WP61_r137144/WP/Interaction/af1f7>
        rdf:type          wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP61_r137144> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP61_r137144/Interaction/af1f7> ;
        wp:participants   <https://identifiers.org/ncbigene/4851> .

<https://identifiers.org/ncbigene/388585>
        rdf:type            wp:Protein , wp:DataNode , wp:Rna ;
        rdfs:label          "HES5" ;
        dc:identifier       <https://identifiers.org/ncbigene/388585> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "388585" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP61_r137144> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000197921> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/388585> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/HES5> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q5TA89> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP61_r137144/DataNode/f80e2> , <http://rdf.wikipathways.org/Pathway/WP61_r137144/DataNode/adc2d> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q5TA89> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/388585> .

<https://identifiers.org/ncbigene/3717>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "JAK2" ;
        dc:identifier       <https://identifiers.org/ncbigene/3717> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "3717" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP61_r137144> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000096968> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/3717> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/JAK2> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/O60674> , <https://identifiers.org/uniprot/A0A1B0GVR5> , <https://identifiers.org/uniprot/A0A1B0GTR9> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP61_r137144/DataNode/d3b5e> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A1B0GVR5> , <http://purl.uniprot.org/uniprot/O60674> , <http://purl.uniprot.org/uniprot/A0A1B0GTR9> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/3717> .

<https://identifiers.org/ncbigene/2932>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "GSK3B" ;
        dc:identifier       <https://identifiers.org/ncbigene/2932> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "2932" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP61_r137144> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000082701> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/2932> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/GSK3B> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A7I2V4G2> , <https://identifiers.org/uniprot/A0A7I2V675> , <https://identifiers.org/uniprot/A0A7I2V2V4> , <https://identifiers.org/uniprot/A0A7I2V3K8> , <https://identifiers.org/uniprot/Q6FI27> , <https://identifiers.org/uniprot/A0A7I2V4X2> , <https://identifiers.org/uniprot/A0A7I2YQK2> , <https://identifiers.org/uniprot/A0A7I2YQG6> , <https://identifiers.org/uniprot/P49841> , <https://identifiers.org/uniprot/A0A7I2V441> , <https://identifiers.org/uniprot/A0A7I2V589> , <https://identifiers.org/uniprot/A0A7I2V606> , <https://identifiers.org/uniprot/A0A7I2V2I5> , <https://identifiers.org/uniprot/A0A7I2V3T3> , <https://identifiers.org/uniprot/A0A7I2YQ81> , <https://identifiers.org/uniprot/A0A7I2V3D8> , <https://identifiers.org/uniprot/A0A7I2YQU1> , <https://identifiers.org/uniprot/A0A7I2V2U4> , <https://identifiers.org/uniprot/A0A7I2V5M2> , <https://identifiers.org/uniprot/A0A7I2V3G9> , <https://identifiers.org/uniprot/A0A7I2V3Z5> , <https://identifiers.org/uniprot/A0A7I2YQB0> , <https://identifiers.org/uniprot/A0A7I2V5K9> , <https://identifiers.org/uniprot/A0A7I2V2Y0> , <https://identifiers.org/uniprot/A0A7I2V2T2> , <https://identifiers.org/uniprot/A0A7I2V5P4> , <https://identifiers.org/uniprot/A0A7I2V626> , <https://identifiers.org/uniprot/A0A7I2V432> , <https://identifiers.org/uniprot/A0A7I2V3A4> , <https://identifiers.org/uniprot/A0A7I2V2N4> , <https://identifiers.org/uniprot/A0A7I2V3S5> , <https://identifiers.org/uniprot/A0A7I2V3N7> , <https://identifiers.org/uniprot/A0A7I2V4X3> , <https://identifiers.org/uniprot/A0A7I2V4F3> , <https://identifiers.org/uniprot/A0A7I2V5G5> , <https://identifiers.org/uniprot/A0A7I2V4W7> , <https://identifiers.org/uniprot/A0A7I2V2K7> , <https://identifiers.org/uniprot/A0A7I2V5B5> , <https://identifiers.org/uniprot/A0A3B3ITW1> , <https://identifiers.org/uniprot/A0A7I2YQK0> , <https://identifiers.org/uniprot/A0A7I2V3J4> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP61_r137144/DataNode/e7972> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A7I2V4X3> , <http://purl.uniprot.org/uniprot/A0A7I2V5K9> , <http://purl.uniprot.org/uniprot/Q6FI27> , <http://purl.uniprot.org/uniprot/A0A7I2YQU1> , <http://purl.uniprot.org/uniprot/A0A7I2V3G9> , <http://purl.uniprot.org/uniprot/A0A7I2V3S5> , <http://purl.uniprot.org/uniprot/A0A7I2V2U4> , <http://purl.uniprot.org/uniprot/A0A7I2V626> , <http://purl.uniprot.org/uniprot/A0A7I2V5B5> , <http://purl.uniprot.org/uniprot/A0A7I2V4F3> , <http://purl.uniprot.org/uniprot/A0A7I2V3D8> , <http://purl.uniprot.org/uniprot/A0A7I2V432> , <http://purl.uniprot.org/uniprot/A0A7I2V4G2> , <http://purl.uniprot.org/uniprot/A0A7I2YQB0> , <http://purl.uniprot.org/uniprot/A0A7I2V4X2> , <http://purl.uniprot.org/uniprot/A0A7I2V2I5> , <http://purl.uniprot.org/uniprot/A0A7I2V606> , <http://purl.uniprot.org/uniprot/A0A7I2V3K8> , <http://purl.uniprot.org/uniprot/P49841> , <http://purl.uniprot.org/uniprot/A0A7I2YQK2> , <http://purl.uniprot.org/uniprot/A0A7I2V675> , <http://purl.uniprot.org/uniprot/A0A7I2YQG6> , <http://purl.uniprot.org/uniprot/A0A7I2V5G5> , <http://purl.uniprot.org/uniprot/A0A7I2V4W7> , <http://purl.uniprot.org/uniprot/A0A7I2YQ81> , <http://purl.uniprot.org/uniprot/A0A7I2V3A4> , <http://purl.uniprot.org/uniprot/A0A7I2V3Z5> , <http://purl.uniprot.org/uniprot/A0A7I2V5M2> , <http://purl.uniprot.org/uniprot/A0A7I2V2N4> , <http://purl.uniprot.org/uniprot/A0A7I2V3T3> , <http://purl.uniprot.org/uniprot/A0A7I2V3J4> , <http://purl.uniprot.org/uniprot/A0A7I2YQK0> , <http://purl.uniprot.org/uniprot/A0A7I2V2T2> , <http://purl.uniprot.org/uniprot/A0A7I2V5P4> , <http://purl.uniprot.org/uniprot/A0A3B3ITW1> , <http://purl.uniprot.org/uniprot/A0A7I2V2V4> , <http://purl.uniprot.org/uniprot/A0A7I2V2K7> , <http://purl.uniprot.org/uniprot/A0A7I2V589> , <http://purl.uniprot.org/uniprot/A0A7I2V2Y0> , <http://purl.uniprot.org/uniprot/A0A7I2V441> , <http://purl.uniprot.org/uniprot/A0A7I2V3N7> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/2932> .

<https://identifiers.org/ncbigene/23462>
        rdf:type            wp:Rna , wp:DataNode ;
        rdfs:label          "HEY1" ;
        dc:identifier       <https://identifiers.org/ncbigene/23462> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "23462" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP61_r137144> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000164683> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/23462> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/HEY1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A6I8PRC2> , <https://identifiers.org/uniprot/A0A6I8PRS3> , <https://identifiers.org/uniprot/E5RHK6> , <https://identifiers.org/uniprot/A0A6I8PU82> , <https://identifiers.org/uniprot/A0A6I8PIY0> , <https://identifiers.org/uniprot/Q9Y5J3> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP61_r137144/DataNode/a3b2b> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A6I8PRS3> , <http://purl.uniprot.org/uniprot/A0A6I8PIY0> , <http://purl.uniprot.org/uniprot/Q9Y5J3> , <http://purl.uniprot.org/uniprot/A0A6I8PU82> , <http://purl.uniprot.org/uniprot/E5RHK6> , <http://purl.uniprot.org/uniprot/A0A6I8PRC2> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/23462> .

<https://identifiers.org/ncbigene/4609>
        rdf:type            wp:Rna , wp:DataNode ;
        rdfs:label          "MYC" ;
        dc:identifier       <https://identifiers.org/ncbigene/4609> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "4609" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP61_r137144> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000136997> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/4609> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/MYC> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/P01106> , <https://identifiers.org/uniprot/Q14899> , <https://identifiers.org/uniprot/A0A494C1T8> , <https://identifiers.org/uniprot/Q16591> , <https://identifiers.org/uniprot/A0A0B4J1R1> , <https://identifiers.org/uniprot/H0YBG3> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP61_r137144/DataNode/d03c4> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P01106> , <http://purl.uniprot.org/uniprot/A0A0B4J1R1> , <http://purl.uniprot.org/uniprot/Q16591> , <http://purl.uniprot.org/uniprot/Q14899> , <http://purl.uniprot.org/uniprot/H0YBG3> , <http://purl.uniprot.org/uniprot/A0A494C1T8> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/4609> .

<http://rdf.wikipathways.org/Pathway/WP61_r137144/WP/Interaction/ide264f5a6>
        rdf:type          wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP61_r137144> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP61_r137144/Interaction/ide264f5a6> .

<https://identifiers.org/ncbigene/2625>
        rdf:type            wp:Rna , wp:DataNode ;
        rdfs:label          "GATA3" ;
        dc:identifier       <https://identifiers.org/ncbigene/2625> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "2625" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP61_r137144> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000107485> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/2625> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/GATA3> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A994J6H6> , <https://identifiers.org/uniprot/A0A2R8Y2A9> , <https://identifiers.org/uniprot/A0A2R8Y4T2> , <https://identifiers.org/uniprot/P23771> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP61_r137144/DataNode/fb5c6> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A2R8Y2A9> , <http://purl.uniprot.org/uniprot/A0A994J6H6> , <http://purl.uniprot.org/uniprot/A0A2R8Y4T2> , <http://purl.uniprot.org/uniprot/P23771> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/2625> .

<https://identifiers.org/ncbigene/1840>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "DTX1" ;
        dc:identifier       <https://identifiers.org/ncbigene/1840> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "1840" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP61_r137144> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000135144> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/1840> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/DTX1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q86Y01> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP61_r137144/DataNode/a216b> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q86Y01> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/1840> .

<https://identifiers.org/ncbigene/8819>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "SAP30" ;
        dc:identifier       <https://identifiers.org/ncbigene/8819> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "8819" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP61_r137144> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000164105> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/8819> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/SAP30> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/O75446> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP61_r137144/DataNode/fe31e> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/O75446> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/8819> .

<https://identifiers.org/ncbigene/5664>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "PSEN1" ;
        dc:identifier       <https://identifiers.org/ncbigene/5664> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "5664" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP61_r137144> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000143801> , <https://identifiers.org/ensembl/ENSG00000288674> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/5664> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/PSEN2> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A7I2V5L1> , <https://identifiers.org/uniprot/A0A7I2V551> , <https://identifiers.org/uniprot/A0A7I2YQG9> , <https://identifiers.org/uniprot/P49810> , <https://identifiers.org/uniprot/E5RJM5> , <https://identifiers.org/uniprot/B1AP22> , <https://identifiers.org/uniprot/A0A7I2V5Y0> , <https://identifiers.org/uniprot/A0A7I2V4T4> , <https://identifiers.org/uniprot/A0A7I2V4Y6> , <https://identifiers.org/uniprot/A0A7I2V4D0> , <https://identifiers.org/uniprot/E5RHT1> , <https://identifiers.org/uniprot/A0A7I2V5S6> , <https://identifiers.org/uniprot/A0A7I2V3R9> , <https://identifiers.org/uniprot/A0A7I2V2W1> , <https://identifiers.org/uniprot/E5RFW4> , <https://identifiers.org/uniprot/A0A7I2V5Q3> , <https://identifiers.org/uniprot/E5RG63> , <https://identifiers.org/uniprot/A0A7I2V355> , <https://identifiers.org/uniprot/A0A7I2V3Y8> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP61_r137144/DataNode/a1fd0> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A7I2YQG9> , <http://purl.uniprot.org/uniprot/A0A7I2V5L1> , <http://purl.uniprot.org/uniprot/A0A7I2V3Y8> , <http://purl.uniprot.org/uniprot/A0A7I2V4Y6> , <http://purl.uniprot.org/uniprot/A0A7I2V5Y0> , <http://purl.uniprot.org/uniprot/A0A7I2V4D0> , <http://purl.uniprot.org/uniprot/E5RG63> , <http://purl.uniprot.org/uniprot/A0A7I2V5Q3> , <http://purl.uniprot.org/uniprot/P49810> , <http://purl.uniprot.org/uniprot/A0A7I2V4T4> , <http://purl.uniprot.org/uniprot/A0A7I2V551> , <http://purl.uniprot.org/uniprot/B1AP22> , <http://purl.uniprot.org/uniprot/A0A7I2V355> , <http://purl.uniprot.org/uniprot/E5RFW4> , <http://purl.uniprot.org/uniprot/E5RHT1> , <http://purl.uniprot.org/uniprot/A0A7I2V2W1> , <http://purl.uniprot.org/uniprot/A0A7I2V3R9> , <http://purl.uniprot.org/uniprot/A0A7I2V5S6> , <http://purl.uniprot.org/uniprot/E5RJM5> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/5664> .

<http://rdf.wikipathways.org/Pathway/WP61_r137144/WP/Interaction/ida736b519>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP61_r137144> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP61_r137144/Interaction/ida736b519> ;
        wp:participants   <https://identifiers.org/ncbigene/9612> , <https://identifiers.org/ncbigene/3065> ;
        wp:source         <https://identifiers.org/ncbigene/3065> ;
        wp:target         <https://identifiers.org/ncbigene/9612> .

<https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=png&pwTitle=Pathway:WP61&oldid=137144>
        rdf:type        foaf:Image ;
        dcterms:format  "image/png" .

<https://identifiers.org/ncbigene/4851>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "NOTCH1" ;
        dc:identifier       <https://identifiers.org/ncbigene/4851> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "4851" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP61_r137144> , <http://rdf.wikipathways.org/Pathway/WP61_r137144/WP/Interaction/af1f7> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000148400> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/4851> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/NOTCH1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A7P0Z4H9> , <https://identifiers.org/uniprot/P46531> , <https://identifiers.org/uniprot/A0A7P0TAK8> , <https://identifiers.org/uniprot/A0A7P0TBG2> , <https://identifiers.org/uniprot/A0A7P0T8U6> , <https://identifiers.org/uniprot/A0A7P0TA56> , <https://identifiers.org/uniprot/A0A7P0T9V1> , <https://identifiers.org/uniprot/A0A7P0T8W1> , <https://identifiers.org/uniprot/A0A7P0TB20> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP61_r137144/DataNode/b887c> , <http://rdf.wikipathways.org/Pathway/WP61_r137144/DataNode/adb30> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A7P0TA56> , <http://purl.uniprot.org/uniprot/A0A7P0T8U6> , <http://purl.uniprot.org/uniprot/A0A7P0TBG2> , <http://purl.uniprot.org/uniprot/A0A7P0TB20> , <http://purl.uniprot.org/uniprot/A0A7P0Z4H9> , <http://purl.uniprot.org/uniprot/A0A7P0T9V1> , <http://purl.uniprot.org/uniprot/A0A7P0T8W1> , <http://purl.uniprot.org/uniprot/P46531> , <http://purl.uniprot.org/uniprot/A0A7P0TAK8> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/4851> .

<https://identifiers.org/ncbigene/10683>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "DLL3" ;
        dc:identifier       <https://identifiers.org/ncbigene/10683> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "10683" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP61_r137144> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000090932> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/10683> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/DLL3> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q9NYJ7> , <https://identifiers.org/uniprot/M0R177> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP61_r137144/DataNode/becf0> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/M0R177> , <http://purl.uniprot.org/uniprot/Q9NYJ7> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/10683> .

<https://identifiers.org/ncbigene/55294>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "FBXW7" ;
        dc:identifier       <https://identifiers.org/ncbigene/55294> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "55294" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP61_r137144> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000109670> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/55294> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/FBXW7> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/S4R3N3> , <https://identifiers.org/uniprot/A0A994J497> , <https://identifiers.org/uniprot/A0A994J6T8> , <https://identifiers.org/uniprot/A0A994J3V4> , <https://identifiers.org/uniprot/G0Z2K0> , <https://identifiers.org/uniprot/Q969H0> , <https://identifiers.org/uniprot/A0A994J6F2> , <https://identifiers.org/uniprot/A0A994J3P3> , <https://identifiers.org/uniprot/S4R3U4> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP61_r137144/DataNode/b339f> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A994J6T8> , <http://purl.uniprot.org/uniprot/G0Z2K0> , <http://purl.uniprot.org/uniprot/A0A994J3V4> , <http://purl.uniprot.org/uniprot/S4R3N3> , <http://purl.uniprot.org/uniprot/A0A994J6F2> , <http://purl.uniprot.org/uniprot/S4R3U4> , <http://purl.uniprot.org/uniprot/Q969H0> , <http://purl.uniprot.org/uniprot/A0A994J3P3> , <http://purl.uniprot.org/uniprot/A0A994J497> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/55294> .

<https://identifiers.org/ncbigene/2033>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "EP300" ;
        dc:identifier       <https://identifiers.org/ncbigene/2033> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "2033" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP61_r137144/WP/Interaction/bc46d> , <https://identifiers.org/wikipathways/WP61_r137144> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000100393> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/2033> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/EP300> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A994J6T4> , <https://identifiers.org/uniprot/A0A994J3N7> , <https://identifiers.org/uniprot/A0A669KB12> , <https://identifiers.org/uniprot/A0A0U1RR87> , <https://identifiers.org/uniprot/Q09472> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP61_r137144/DataNode/f69d9> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q09472> , <http://purl.uniprot.org/uniprot/A0A0U1RR87> , <http://purl.uniprot.org/uniprot/A0A994J3N7> , <http://purl.uniprot.org/uniprot/A0A669KB12> , <http://purl.uniprot.org/uniprot/A0A994J6T4> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/2033> .

<https://identifiers.org/ncbigene/3066>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "HDAC2" ;
        dc:identifier       <https://identifiers.org/ncbigene/3066> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "3066" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP61_r137144> , <http://rdf.wikipathways.org/Pathway/WP61_r137144/WP/Interaction/idc0a55e04> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000196591> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/3066> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/HDAC2> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q92769> , <https://identifiers.org/uniprot/E5RHE7> , <https://identifiers.org/uniprot/E5RGV4> , <https://identifiers.org/uniprot/E5RJ04> , <https://identifiers.org/uniprot/E5RH52> , <https://identifiers.org/uniprot/E5RFP9> , <https://identifiers.org/uniprot/H3BM24> , <https://identifiers.org/uniprot/E5RK19> , <https://identifiers.org/uniprot/E5RFI6> , <https://identifiers.org/uniprot/E5RG37> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP61_r137144/DataNode/a4860> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/E5RG37> , <http://purl.uniprot.org/uniprot/E5RFI6> , <http://purl.uniprot.org/uniprot/H3BM24> , <http://purl.uniprot.org/uniprot/E5RJ04> , <http://purl.uniprot.org/uniprot/E5RH52> , <http://purl.uniprot.org/uniprot/E5RGV4> , <http://purl.uniprot.org/uniprot/E5RFP9> , <http://purl.uniprot.org/uniprot/Q92769> , <http://purl.uniprot.org/uniprot/E5RHE7> , <http://purl.uniprot.org/uniprot/E5RK19> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/3066> .

<https://identifiers.org/ncbigene/51107>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "APH1A" ;
        dc:identifier       <https://identifiers.org/ncbigene/51107> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "51107" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP61_r137144> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000117362> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/51107> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/APH1A> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q5TB21> , <https://identifiers.org/uniprot/Q96BI3> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP61_r137144/DataNode/ab0aa> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q5TB21> , <http://purl.uniprot.org/uniprot/Q96BI3> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/51107> .

<https://identifiers.org/ncbigene/6714>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "SRC" ;
        dc:identifier       <https://identifiers.org/ncbigene/6714> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "6714" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP61_r137144> , <http://rdf.wikipathways.org/Pathway/WP61_r137144/WP/Interaction/d574e> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000197122> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/6714> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/SRC> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A8I5KYU4> , <https://identifiers.org/uniprot/P12931> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP61_r137144/DataNode/dfd8e> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P12931> , <http://purl.uniprot.org/uniprot/A0A8I5KYU4> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/6714> .

<https://identifiers.org/ncbigene/6868>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "ADAM17" ;
        dc:identifier       <https://identifiers.org/ncbigene/6868> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "6868" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP61_r137144> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000151694> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/6868> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/ADAM17> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A8V8TPG8> , <https://identifiers.org/uniprot/A0A3B3ITB5> , <https://identifiers.org/uniprot/A0A8V8TNK2> , <https://identifiers.org/uniprot/A0A8V8TPV7> , <https://identifiers.org/uniprot/A0A8V8TN27> , <https://identifiers.org/uniprot/A0A3B3ISQ1> , <https://identifiers.org/uniprot/B2RNB2> , <https://identifiers.org/uniprot/A0A3B3IST4> , <https://identifiers.org/uniprot/A8K1B4> , <https://identifiers.org/uniprot/A6H8L4> , <https://identifiers.org/uniprot/P78536> , <https://identifiers.org/uniprot/A0A3B3ITW9> , <https://identifiers.org/uniprot/A0A8V8TNK7> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP61_r137144/DataNode/a98cf> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A8V8TPV7> , <http://purl.uniprot.org/uniprot/A6H8L4> , <http://purl.uniprot.org/uniprot/A0A3B3ITB5> , <http://purl.uniprot.org/uniprot/A0A8V8TNK2> , <http://purl.uniprot.org/uniprot/A0A3B3ITW9> , <http://purl.uniprot.org/uniprot/B2RNB2> , <http://purl.uniprot.org/uniprot/A8K1B4> , <http://purl.uniprot.org/uniprot/P78536> , <http://purl.uniprot.org/uniprot/A0A8V8TPG8> , <http://purl.uniprot.org/uniprot/A0A8V8TN27> , <http://purl.uniprot.org/uniprot/A0A3B3IST4> , <http://purl.uniprot.org/uniprot/A0A8V8TNK7> , <http://purl.uniprot.org/uniprot/A0A3B3ISQ1> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/6868> .

<https://identifiers.org/ncbigene/1026>
        rdf:type            wp:DataNode , wp:Rna ;
        rdfs:label          "CDKN1A" ;
        dc:identifier       <https://identifiers.org/ncbigene/1026> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "1026" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP61_r137144> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000124762> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/1026> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/CDKN1A> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/P38936> , <https://identifiers.org/uniprot/A0A024RCX5> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP61_r137144/DataNode/ca2b1> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P38936> , <http://purl.uniprot.org/uniprot/A0A024RCX5> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/1026> .

<https://identifiers.org/ncbigene/3280>
        rdf:type            wp:Protein , wp:Rna , wp:DataNode ;
        rdfs:label          "HEY1" , "HES1" ;
        dc:identifier       <https://identifiers.org/ncbigene/3280> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "3280" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP61_r137144> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000114315> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/3280> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/HES1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q14469> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP61_r137144/DataNode/cec0f> , <http://rdf.wikipathways.org/Pathway/WP61_r137144/DataNode/eca18> , <http://rdf.wikipathways.org/Pathway/WP61_r137144/DataNode/a3bbc> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q14469> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/3280> .

<https://identifiers.org/ncbigene/3516>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "RBPJ" ;
        dc:identifier       <https://identifiers.org/ncbigene/3516> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "3516" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP61_r137144> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000168214> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/3516> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/RBPJ> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/D6RB37> , <https://identifiers.org/uniprot/D6R9K5> , <https://identifiers.org/uniprot/A0A7P0T848> , <https://identifiers.org/uniprot/A0A7P0T806> , <https://identifiers.org/uniprot/D6R946> , <https://identifiers.org/uniprot/A0A7P0T821> , <https://identifiers.org/uniprot/A0A7P0Z4N7> , <https://identifiers.org/uniprot/D6RCM1> , <https://identifiers.org/uniprot/D6REC2> , <https://identifiers.org/uniprot/A0A7P0T9Y9> , <https://identifiers.org/uniprot/Q06330> , <https://identifiers.org/uniprot/D6RF98> , <https://identifiers.org/uniprot/A0A7P0T947> , <https://identifiers.org/uniprot/A0A7P0T7Z3> , <https://identifiers.org/uniprot/D6RIZ8> , <https://identifiers.org/uniprot/A0A7P0TBJ4> , <https://identifiers.org/uniprot/A0A7P0T9W9> , <https://identifiers.org/uniprot/D6RIV8> , <https://identifiers.org/uniprot/H0Y8R3> , <https://identifiers.org/uniprot/A0A7P0T964> , <https://identifiers.org/uniprot/D6RBQ8> , <https://identifiers.org/uniprot/D6R927> , <https://identifiers.org/uniprot/D6RA45> , <https://identifiers.org/uniprot/A0A7P0TA33> , <https://identifiers.org/uniprot/D6RAT2> , <https://identifiers.org/uniprot/D6R9X3> , <https://identifiers.org/uniprot/D6REP3> , <https://identifiers.org/uniprot/D6RE93> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP61_r137144/DataNode/b3463> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/D6RBQ8> , <http://purl.uniprot.org/uniprot/D6RCM1> , <http://purl.uniprot.org/uniprot/D6R927> , <http://purl.uniprot.org/uniprot/H0Y8R3> , <http://purl.uniprot.org/uniprot/A0A7P0T806> , <http://purl.uniprot.org/uniprot/D6R9K5> , <http://purl.uniprot.org/uniprot/A0A7P0TBJ4> , <http://purl.uniprot.org/uniprot/Q06330> , <http://purl.uniprot.org/uniprot/A0A7P0Z4N7> , <http://purl.uniprot.org/uniprot/A0A7P0T821> , <http://purl.uniprot.org/uniprot/D6REC2> , <http://purl.uniprot.org/uniprot/D6RIZ8> , <http://purl.uniprot.org/uniprot/D6RE93> , <http://purl.uniprot.org/uniprot/D6REP3> , <http://purl.uniprot.org/uniprot/A0A7P0T9W9> , <http://purl.uniprot.org/uniprot/D6RAT2> , <http://purl.uniprot.org/uniprot/D6RF98> , <http://purl.uniprot.org/uniprot/A0A7P0T848> , <http://purl.uniprot.org/uniprot/D6RA45> , <http://purl.uniprot.org/uniprot/A0A7P0T964> , <http://purl.uniprot.org/uniprot/D6RIV8> , <http://purl.uniprot.org/uniprot/D6R946> , <http://purl.uniprot.org/uniprot/A0A7P0T7Z3> , <http://purl.uniprot.org/uniprot/A0A7P0TA33> , <http://purl.uniprot.org/uniprot/D6RB37> , <http://purl.uniprot.org/uniprot/A0A7P0T9Y9> , <http://purl.uniprot.org/uniprot/D6R9X3> , <http://purl.uniprot.org/uniprot/A0A7P0T947> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/3516> .

<https://identifiers.org/ncbigene/5663>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "PSEN2" ;
        dc:identifier       <https://identifiers.org/ncbigene/5663> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "5663" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP61_r137144> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000080815> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/5663> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/PSEN1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/G3V490> , <https://identifiers.org/uniprot/A0A8V8TPL5> , <https://identifiers.org/uniprot/A0A8V8TQ90> , <https://identifiers.org/uniprot/A0A8V8TQ53> , <https://identifiers.org/uniprot/P49768> , <https://identifiers.org/uniprot/G3V449> , <https://identifiers.org/uniprot/A0A8V8TPK5> , <https://identifiers.org/uniprot/H0YM52> , <https://identifiers.org/uniprot/A0A8V8TQT3> , <https://identifiers.org/uniprot/A0A8V8TQU9> , <https://identifiers.org/uniprot/A0A8V8TQV2> , <https://identifiers.org/uniprot/A0A0S2Z4D2> , <https://identifiers.org/uniprot/A0A8V8TQ36> , <https://identifiers.org/uniprot/H0YNU4> , <https://identifiers.org/uniprot/G3V519> , <https://identifiers.org/uniprot/A0A024R6A3> , <https://identifiers.org/uniprot/A0A8V8TPL0> , <https://identifiers.org/uniprot/A0A8V8TQ93> , <https://identifiers.org/uniprot/A0A8V8TQ54> , <https://identifiers.org/uniprot/A0A8V8TLT5> , <https://identifiers.org/uniprot/A0A8V8TQU7> , <https://identifiers.org/uniprot/A0A8V8TR55> , <https://identifiers.org/uniprot/G3V4M0> , <https://identifiers.org/uniprot/G3V2G7> , <https://identifiers.org/uniprot/G3V3P0> , <https://identifiers.org/uniprot/A0A8V8TR50> , <https://identifiers.org/uniprot/G3V3Z0> , <https://identifiers.org/uniprot/A0A8V8TR52> , <https://identifiers.org/uniprot/A0A8V8TQ58> , <https://identifiers.org/uniprot/A0A8V8TQ30> , <https://identifiers.org/uniprot/G3V4P4> , <https://identifiers.org/uniprot/G3V2B1> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP61_r137144/DataNode/f0084> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A8V8TQ30> , <http://purl.uniprot.org/uniprot/G3V4M0> , <http://purl.uniprot.org/uniprot/G3V449> , <http://purl.uniprot.org/uniprot/A0A8V8TQV2> , <http://purl.uniprot.org/uniprot/A0A8V8TPK5> , <http://purl.uniprot.org/uniprot/A0A8V8TR55> , <http://purl.uniprot.org/uniprot/H0YNU4> , <http://purl.uniprot.org/uniprot/A0A8V8TQ53> , <http://purl.uniprot.org/uniprot/A0A8V8TQ54> , <http://purl.uniprot.org/uniprot/A0A8V8TQ93> , <http://purl.uniprot.org/uniprot/G3V2B1> , <http://purl.uniprot.org/uniprot/G3V3Z0> , <http://purl.uniprot.org/uniprot/A0A8V8TPL5> , <http://purl.uniprot.org/uniprot/A0A8V8TR52> , <http://purl.uniprot.org/uniprot/A0A8V8TQT3> , <http://purl.uniprot.org/uniprot/H0YM52> , <http://purl.uniprot.org/uniprot/G3V519> , <http://purl.uniprot.org/uniprot/G3V490> , <http://purl.uniprot.org/uniprot/G3V2G7> , <http://purl.uniprot.org/uniprot/G3V3P0> , <http://purl.uniprot.org/uniprot/A0A8V8TQU7> , <http://purl.uniprot.org/uniprot/A0A8V8TLT5> , <http://purl.uniprot.org/uniprot/A0A8V8TQ58> , <http://purl.uniprot.org/uniprot/A0A8V8TQ90> , <http://purl.uniprot.org/uniprot/P49768> , <http://purl.uniprot.org/uniprot/A0A8V8TPL0> , <http://purl.uniprot.org/uniprot/A0A024R6A3> , <http://purl.uniprot.org/uniprot/A0A8V8TQ36> , <http://purl.uniprot.org/uniprot/A0A8V8TR50> , <http://purl.uniprot.org/uniprot/G3V4P4> , <http://purl.uniprot.org/uniprot/A0A0S2Z4D2> , <http://purl.uniprot.org/uniprot/A0A8V8TQU9> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/5663> .

<https://identifiers.org/ncbigene/23013>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "SPEN" ;
        dc:identifier       <https://identifiers.org/ncbigene/23013> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "23013" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP61_r137144> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000065526> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/23013> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/SPEN> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A669KB49> , <https://identifiers.org/uniprot/Q96T58> , <https://identifiers.org/uniprot/H0Y5U7> , <https://identifiers.org/uniprot/F6WRY4> , <https://identifiers.org/uniprot/A0A994J7B7> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP61_r137144/DataNode/f6495> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A669KB49> , <http://purl.uniprot.org/uniprot/H0Y5U7> , <http://purl.uniprot.org/uniprot/F6WRY4> , <http://purl.uniprot.org/uniprot/A0A994J7B7> , <http://purl.uniprot.org/uniprot/Q96T58> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/23013> .

<https://identifiers.org/ncbigene/22938>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "SNW1" ;
        dc:identifier       <https://identifiers.org/ncbigene/22938> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "22938" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP61_r137144> , <http://rdf.wikipathways.org/Pathway/WP61_r137144/WP/Interaction/id54ed83a> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000100603> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/22938> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/SNW1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/G3V4X8> , <https://identifiers.org/uniprot/G3V5R3> , <https://identifiers.org/uniprot/G3V4E0> , <https://identifiers.org/uniprot/Q13573> , <https://identifiers.org/uniprot/G3V3A4> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP61_r137144/DataNode/aab34> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/G3V4X8> , <http://purl.uniprot.org/uniprot/G3V5R3> , <http://purl.uniprot.org/uniprot/Q13573> , <http://purl.uniprot.org/uniprot/G3V4E0> , <http://purl.uniprot.org/uniprot/G3V3A4> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/22938> .

<https://identifiers.org/ncbigene/8454>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "CUL1" ;
        dc:identifier       <https://identifiers.org/ncbigene/8454> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "8454" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP61_r137144> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000055130> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/8454> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/CUL1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A590UJ50> , <https://identifiers.org/uniprot/A0A590UJM8> , <https://identifiers.org/uniprot/A0A090N7U0> , <https://identifiers.org/uniprot/A0A590UJ59> , <https://identifiers.org/uniprot/A0A590UJA0> , <https://identifiers.org/uniprot/A0A590UJ97> , <https://identifiers.org/uniprot/A0A590UJC4> , <https://identifiers.org/uniprot/A0A590UJR3> , <https://identifiers.org/uniprot/A0A590UK34> , <https://identifiers.org/uniprot/A0A590UJ56> , <https://identifiers.org/uniprot/Q13616> , <https://identifiers.org/uniprot/A0A590UJ21> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP61_r137144/DataNode/f3bb9> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A590UJA0> , <http://purl.uniprot.org/uniprot/A0A590UJ59> , <http://purl.uniprot.org/uniprot/A0A590UJC4> , <http://purl.uniprot.org/uniprot/Q13616> , <http://purl.uniprot.org/uniprot/A0A590UJ97> , <http://purl.uniprot.org/uniprot/A0A590UK34> , <http://purl.uniprot.org/uniprot/A0A590UJ50> , <http://purl.uniprot.org/uniprot/A0A590UJ21> , <http://purl.uniprot.org/uniprot/A0A590UJ56> , <http://purl.uniprot.org/uniprot/A0A590UJM8> , <http://purl.uniprot.org/uniprot/A0A590UJR3> , <http://purl.uniprot.org/uniprot/A0A090N7U0> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/8454> .

<https://identifiers.org/ncbigene/6015>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "RING1" ;
        dc:identifier       <https://identifiers.org/ncbigene/6015> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "6015" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP61_r137144> , <http://rdf.wikipathways.org/Pathway/WP61_r137144/WP/Interaction/iddf54d7b4> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000204227> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/6015> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/RING1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A1U9X8F2> , <https://identifiers.org/uniprot/Q06587> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP61_r137144/DataNode/aa7fa> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A1U9X8F2> , <http://purl.uniprot.org/uniprot/Q06587> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/6015> .

<https://identifiers.org/ncbigene/55851>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "PSENEN" ;
        dc:identifier       <https://identifiers.org/ncbigene/55851> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "55851" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP61_r137144> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000205155> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/55851> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/PSENEN> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/K7ES79> , <https://identifiers.org/uniprot/Q9NZ42> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP61_r137144/DataNode/ed9ff> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q9NZ42> , <http://purl.uniprot.org/uniprot/K7ES79> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/55851> .

<https://identifiers.org/ncbigene/2273>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "FHL1" ;
        dc:identifier       <https://identifiers.org/ncbigene/2273> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "2273" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP61_r137144> , <http://rdf.wikipathways.org/Pathway/WP61_r137144/WP/Interaction/iddf54d7b4> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000022267> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/2273> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/FHL1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q13642> , <https://identifiers.org/uniprot/A0A0D9SGB2> , <https://identifiers.org/uniprot/A0A0D9SFZ9> , <https://identifiers.org/uniprot/Q5JXI8> , <https://identifiers.org/uniprot/Q5JXH8> , <https://identifiers.org/uniprot/A0A494C1G1> , <https://identifiers.org/uniprot/A0A0D9SFI6> , <https://identifiers.org/uniprot/A0A0D9SEY7> , <https://identifiers.org/uniprot/A0A494C0D6> , <https://identifiers.org/uniprot/A0A0D9SGD1> , <https://identifiers.org/uniprot/Q5JXI3> , <https://identifiers.org/uniprot/Q5JXI0> , <https://identifiers.org/uniprot/Q5JXI2> , <https://identifiers.org/uniprot/Q5JXH7> , <https://identifiers.org/uniprot/A0A0D9SGC5> , <https://identifiers.org/uniprot/A0A0D9SFB0> , <https://identifiers.org/uniprot/A0A494C0J3> , <https://identifiers.org/uniprot/Q5JXH9> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP61_r137144/DataNode/df1db> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q5JXI3> , <http://purl.uniprot.org/uniprot/A0A0D9SFZ9> , <http://purl.uniprot.org/uniprot/A0A0D9SFI6> , <http://purl.uniprot.org/uniprot/A0A0D9SEY7> , <http://purl.uniprot.org/uniprot/Q5JXH7> , <http://purl.uniprot.org/uniprot/A0A494C1G1> , <http://purl.uniprot.org/uniprot/A0A0D9SGB2> , <http://purl.uniprot.org/uniprot/A0A0D9SGD1> , <http://purl.uniprot.org/uniprot/Q5JXI0> , <http://purl.uniprot.org/uniprot/A0A0D9SGC5> , <http://purl.uniprot.org/uniprot/Q5JXH8> , <http://purl.uniprot.org/uniprot/A0A494C0J3> , <http://purl.uniprot.org/uniprot/Q5JXI2> , <http://purl.uniprot.org/uniprot/A0A0D9SFB0> , <http://purl.uniprot.org/uniprot/Q5JXI8> , <http://purl.uniprot.org/uniprot/A0A494C0D6> , <http://purl.uniprot.org/uniprot/Q5JXH9> , <http://purl.uniprot.org/uniprot/Q13642> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/2273> .

<https://identifiers.org/hgnc.symbol/MTOR>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "MTOR" ;
        dc:identifier       <https://identifiers.org/hgnc.symbol/MTOR> ;
        dc:source           "HGNC" ;
        dcterms:identifier  "MTOR" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP61_r137144> , <http://rdf.wikipathways.org/Pathway/WP61_r137144/WP/Interaction/edbee> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSOANG00000021332> , <https://identifiers.org/ensembl/ENSG00000198793> , <https://identifiers.org/ensembl/ENSSSCG00000003413> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/100079751> , <https://identifiers.org/ncbigene/2475> , <https://identifiers.org/ncbigene/100127359> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/MTOR> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A8V8TQP2> , <https://identifiers.org/uniprot/A0A287BKJ8> , <https://identifiers.org/uniprot/A0A8V8TQ52> , <https://identifiers.org/uniprot/A0A8V8TQN3> , <https://identifiers.org/uniprot/F1RHR8> , <https://identifiers.org/uniprot/A0A8V8TR74> , <https://identifiers.org/uniprot/A0A4X1W882> , <https://identifiers.org/uniprot/P42345> , <https://identifiers.org/uniprot/A0A8V8TRG9> , <https://identifiers.org/uniprot/F6S221> , <https://identifiers.org/uniprot/A0A8V8TQM6> , <https://identifiers.org/uniprot/A0A287BMJ2> , <https://identifiers.org/uniprot/A0A4X1W7H7> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP61_r137144/DataNode/d7647> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A287BKJ8> , <http://purl.uniprot.org/uniprot/A0A8V8TR74> , <http://purl.uniprot.org/uniprot/A0A4X1W7H7> , <http://purl.uniprot.org/uniprot/A0A8V8TQM6> , <http://purl.uniprot.org/uniprot/A0A8V8TRG9> , <http://purl.uniprot.org/uniprot/A0A4X1W882> , <http://purl.uniprot.org/uniprot/A0A8V8TQN3> , <http://purl.uniprot.org/uniprot/F1RHR8> , <http://purl.uniprot.org/uniprot/P42345> , <http://purl.uniprot.org/uniprot/F6S221> , <http://purl.uniprot.org/uniprot/A0A8V8TQ52> , <http://purl.uniprot.org/uniprot/A0A287BMJ2> , <http://purl.uniprot.org/uniprot/A0A8V8TQP2> ;
        foaf:page           <https://www.genenames.org/data/gene-symbol-report/#!/symbol/MTOR> .

<https://identifiers.org/pmc/PMC9317794>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed Central" ;
        dcterms:identifier  "PMC9317794" ;
        cito:cites          <https://identifiers.org/wikipathways/WP61> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/PMC9317794> .

<http://rdf.wikipathways.org/Pathway/WP61_r137144/WP/Interaction/id1a79caf>
        rdf:type          wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP61_r137144> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP61_r137144/Interaction/id1a79caf> ;
        wp:participants   <https://identifiers.org/ncbigene/9541> .

<http://rdf.wikipathways.org/Pathway/WP61_r137144/WP/Interaction/ida3d454b5>
        rdf:type          wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP61_r137144> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP61_r137144/Interaction/ida3d454b5> .

<https://identifiers.org/ncbigene/3065>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "HDAC1" ;
        dc:identifier       <https://identifiers.org/ncbigene/3065> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "3065" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP61_r137144/WP/Interaction/ida736b519> , <https://identifiers.org/wikipathways/WP61_r137144> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000116478> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/3065> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/HDAC1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q5TEE2> , <https://identifiers.org/uniprot/Q13547> , <https://identifiers.org/uniprot/Q6IT96> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP61_r137144/DataNode/d6d1f> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q6IT96> , <http://purl.uniprot.org/uniprot/Q13547> , <http://purl.uniprot.org/uniprot/Q5TEE2> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/3065> .

<https://identifiers.org/ncbigene/28514>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "DLL1" ;
        dc:identifier       <https://identifiers.org/ncbigene/28514> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "28514" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP61_r137144/WP/Interaction/e3e6d> , <https://identifiers.org/wikipathways/WP61_r137144> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000198719> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/28514> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/DLL1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/O00548> , <https://identifiers.org/uniprot/A0A384P5C6> , <https://identifiers.org/uniprot/A0A0D9SF76> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP61_r137144/DataNode/fe22a> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A384P5C6> , <http://purl.uniprot.org/uniprot/A0A0D9SF76> , <http://purl.uniprot.org/uniprot/O00548> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/28514> .
