@prefix biopax:  <http://www.biopax.org/release/biopax-level3.owl#> .
@prefix cito:    <http://purl.org/spar/cito/> .
@prefix dc:      <http://purl.org/dc/elements/1.1/> .
@prefix dcterms: <http://purl.org/dc/terms/> .
@prefix foaf:    <http://xmlns.com/foaf/0.1/> .
@prefix freq:    <http://purl.org/cld/freq/> .
@prefix gpml:    <http://vocabularies.wikipathways.org/gpml#> .
@prefix obo:     <http://purl.obolibrary.org/obo/> .
@prefix owl:     <http://www.w3.org/2002/07/owl#> .
@prefix pav:     <http://purl.org/pav/> .
@prefix prov:    <http://www.w3.org/ns/prov#> .
@prefix rdf:     <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix rdfs:    <http://www.w3.org/2000/01/rdf-schema#> .
@prefix skos:    <http://www.w3.org/2004/02/skos/core#> .
@prefix void:    <http://rdfs.org/ns/void#> .
@prefix wp:      <http://vocabularies.wikipathways.org/wp#> .
@prefix wprdf:   <http://rdf.wikipathways.org/> .
@prefix xsd:     <http://www.w3.org/2001/XMLSchema#> .

<http://rdf.wikipathways.org/Pathway/WP4357_r140180/ComplexBinding/f0186>
        rdf:type                       wp:Binding , wp:ComplexBinding , wp:Interaction ;
        dcterms:bibliographicCitation  <https://identifiers.org/pubmed/23434765> ;
        dcterms:isPartOf               <https://identifiers.org/wikipathways/WP4357_r140180> ;
        wp:isAbout                     <http://rdf.wikipathways.org/Pathway/WP4357_r140180/Group/f0186> ;
        wp:participants                <https://identifiers.org/ensembl/ENSG00000036257> , <https://identifiers.org/ensembl/ENSG00000100387> , <https://identifiers.org/ncbigene/9817> , <https://identifiers.org/ncbigene/4780> , <http://rdf.wikipathways.org/Pathway/WP4357_r140180/Complex/f0186> .

<http://rdf.wikipathways.org/Pathway/WP4357_r140180/ComplexBinding/fd81c>
        rdf:type          wp:ComplexBinding , wp:Binding , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4357_r140180> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4357_r140180/Group/fd81c> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000036257> , <https://identifiers.org/ensembl/ENSG00000100387> , <https://identifiers.org/ncbigene/9817> , <http://rdf.wikipathways.org/Pathway/WP4357_r140180/Complex/fd81c> .

<http://rdf.wikipathways.org/Pathway/WP4357_r140180/WP/Interaction/id96cf4eb>
        rdf:type            wp:DirectedInteraction , wp:Catalysis , wp:Interaction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4357_r140180> ;
        dcterms:references  <https://identifiers.org/pubmed/22819548> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4357_r140180/Interaction/id96cf4eb> ;
        wp:participants     <http://rdf.wikipathways.org/Pathway/WP4357_r140180/WP/Interaction/id8704cb60> , <http://rdf.wikipathways.org/Pathway/WP4357_r140180/Complex/d4421> ;
        wp:source           <http://rdf.wikipathways.org/Pathway/WP4357_r140180/Complex/d4421> ;
        wp:target           <http://rdf.wikipathways.org/Pathway/WP4357_r140180/WP/Interaction/id8704cb60> .

<https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=svg&pwTitle=Pathway:WP4357&oldid=140180>
        rdf:type        foaf:Image ;
        dcterms:format  "image/svg+xml" .

<https://identifiers.org/ncbigene/2730>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "GCLM" ;
        dc:identifier       <https://identifiers.org/ncbigene/2730> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "2730" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4357_r140180> , <http://rdf.wikipathways.org/Pathway/WP4357_r140180/Complex/dc9de> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000023909> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/2730> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/GCLM> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/P48507> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4357_r140180/DataNode/f5ed1> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P48507> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/2730> .

<https://identifiers.org/wikipathways/WP4357_r140180>
        rdf:type               skos:Collection , wp:Pathway ;
        dc:identifier          <https://identifiers.org/wikipathways/WP4357> ;
        dc:source              "WikiPathways" ;
        dc:title               "NRF2-ARE regulation"@en ;
        dcterms:description    "Under basal conditions, Nrf2 is sequestered to the cytoplasm through binding with Keap1/Cul3/RBX1 and continually degraded via the proteasome. On early response to external stressors, Keap1 is oxidized or Nrf2 is phosphorylated by PKC. Nrf2 then translocates into the nucleus and binds to ARE (antioxidant-responsive) genes in order to increase or decrease transcription. A delayed response to external stressors causes phosphorylation of GSK-3β (by unknown tyrosine kinases), GSK-3β then activates Src kinases, which then translocate to the nucleus. Src kinases phosphorylate Nrf2 (Tyr568) which allows for nuclear export, ubiquitination and degradation of Nrf2. If insulin receptor signaling is initiated, GSK-3β activity is inhibited. Keap1 is also able to regulate Nrf2 activity through sequestration with PGAM5 to the mitochondria. In addition, PI3K also phosphorylates the CEBPB, inducing its translocation to the nucleus where it binds to the CEBPB response element within the xenobiotic response element, in conjunction with NRF2 binding to ARE.\n\nDescription was adapted from Fig 1 in Vomhof-Dekrey et al, and Fig 4 in Surh et al.\nProtein phosphorylation sites were added based on information from [PhosphoSitePlus (R)](https://www.phosphosite.org)." ;
        dcterms:identifier     "WP4357" ;
        dcterms:references     <https://identifiers.org/pubmed/25514926> ;
        cito:cites             <https://identifiers.org/pubmed/14570043> , <https://identifiers.org/pubmed/22819548> , <https://identifiers.org/pubmed/23434765> , <https://identifiers.org/pubmed/25514926> ;
        wp:isAbout             <http://rdf.wikipathways.org/Pathway/WP4357_r140180> ;
        wp:ontologyTag         wp:Curation:ONTOX , obo:PW_0000369 , obo:PW_0000378 , wp:Curation:AnalysisCollection ;
        wp:organism            obo:NCBITaxon_9606 ;
        wp:organismName        "Homo sapiens" ;
        wp:pathwayOntologyTag  obo:PW_0000378 , obo:PW_0000369 ;
        foaf:img               <https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=svg&pwTitle=Pathway:WP4357&oldid=140180> , <https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=png&pwTitle=Pathway:WP4357&oldid=140180> ;
        foaf:page              <http://www.wikipathways.org/instance/WP4357_r140180> .

<http://rdf.wikipathways.org/Pathway/WP4357_r140180/Complex/c2358>
        rdf:type          wp:Complex , wp:DataNode ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4357_r140180> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4357_r140180/Group/c2358> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000197122> , <https://identifiers.org/ensembl/ENSG00000010810> , <https://identifiers.org/ensembl/ENSG00000176105> .

<https://identifiers.org/ensembl/ENSG00000036257>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "CUL3" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000036257> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000036257" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4357_r140180> , <http://rdf.wikipathways.org/Pathway/WP4357_r140180/Complex/fd81c> , <http://rdf.wikipathways.org/Pathway/WP4357_r140180/Complex/f0186> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000036257> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/8452> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/CUL3> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q13618> , <https://identifiers.org/uniprot/A0A024R475> , <https://identifiers.org/uniprot/H7C399> , <https://identifiers.org/uniprot/A0A087X1R9> , <https://identifiers.org/uniprot/H7C1L6> , <https://identifiers.org/uniprot/H7C1J0> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18032944> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4357_r140180/DataNode/c99d1> , <http://rdf.wikipathways.org/Pathway/WP4357_r140180/DataNode/b40c9> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A087X1R9> , <http://purl.uniprot.org/uniprot/A0A024R475> , <http://purl.uniprot.org/uniprot/H7C1J0> , <http://purl.uniprot.org/uniprot/Q13618> , <http://purl.uniprot.org/uniprot/H7C1L6> , <http://purl.uniprot.org/uniprot/H7C399> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000036257> .

<http://rdf.wikipathways.org/Pathway/WP4357_r140180/WP/Interaction/idd08f0d74>
        rdf:type            wp:DirectedInteraction , wp:Interaction , wp:Inhibition ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4357_r140180> ;
        dcterms:references  <https://identifiers.org/pubmed/22819548> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4357_r140180/Interaction/idd08f0d74> ;
        wp:participants     <https://identifiers.org/ensembl/ENSG00000171105> , <https://identifiers.org/ensembl/ENSG00000082701> ;
        wp:source           <https://identifiers.org/ensembl/ENSG00000171105> ;
        wp:target           <https://identifiers.org/ensembl/ENSG00000082701> .

<http://rdf.wikipathways.org/Pathway/WP4357_r140180/ComplexBinding/d4421>
        rdf:type          wp:ComplexBinding , wp:Binding , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4357_r140180> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4357_r140180/Group/d4421> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000197122> , <https://identifiers.org/ensembl/ENSG00000176105> , <https://identifiers.org/ensembl/ENSG00000010810> , <http://rdf.wikipathways.org/Pathway/WP4357_r140180/Complex/d4421> .

<https://identifiers.org/ncbigene/9817>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "KEAP1" ;
        dc:identifier       <https://identifiers.org/ncbigene/9817> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "9817" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4357_r140180> , <http://rdf.wikipathways.org/Pathway/WP4357_r140180/Complex/fd81c> , <http://rdf.wikipathways.org/Pathway/WP4357_r140180/Complex/f0186> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000079999> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/9817> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/KEAP1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/K7EQX2> , <https://identifiers.org/uniprot/K7ESE0> , <https://identifiers.org/uniprot/Q14145> , <https://identifiers.org/uniprot/K7EPZ3> , <https://identifiers.org/uniprot/K7EJ49> , <https://identifiers.org/uniprot/K7EJD8> , <https://identifiers.org/uniprot/A0A024R7C0> , <https://identifiers.org/uniprot/K7EMY1> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4357_r140180/DataNode/e3f69> , <http://rdf.wikipathways.org/Pathway/WP4357_r140180/DataNode/da326> , <http://rdf.wikipathways.org/Pathway/WP4357_r140180/DataNode/a6716> , <http://rdf.wikipathways.org/Pathway/WP4357_r140180/DataNode/fe1e6> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q14145> , <http://purl.uniprot.org/uniprot/K7EJD8> , <http://purl.uniprot.org/uniprot/K7EJ49> , <http://purl.uniprot.org/uniprot/K7EQX2> , <http://purl.uniprot.org/uniprot/K7EMY1> , <http://purl.uniprot.org/uniprot/K7ESE0> , <http://purl.uniprot.org/uniprot/A0A024R7C0> , <http://purl.uniprot.org/uniprot/K7EPZ3> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/9817> .

<https://identifiers.org/ensembl/ENSG00000247077>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "PGAM5" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000247077> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000247077" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4357_r140180> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000247077> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/192111> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/PGAM5> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A994J4Y8> , <https://identifiers.org/uniprot/Q96HS1> , <https://identifiers.org/uniprot/F5GXG4> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18053024> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4357_r140180/DataNode/c5372> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A994J4Y8> , <http://purl.uniprot.org/uniprot/F5GXG4> , <http://purl.uniprot.org/uniprot/Q96HS1> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000247077> .

<https://identifiers.org/pubmed/22819548>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "22819548" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4357_r140180/WP/Interaction/idd08f0d74> , <http://rdf.wikipathways.org/Pathway/WP4357_r140180/WP/Interaction/id96cf4eb> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/22819548> .

<https://identifiers.org/ncbigene/5290>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "PI3K" ;
        dc:identifier       <https://identifiers.org/ncbigene/5290> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "5290" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4357_r140180> , <http://rdf.wikipathways.org/Pathway/WP4357_r140180/WP/Interaction/bff9c> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000121879> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/5290> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/PIK3CA> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A2R8Y2F6> , <https://identifiers.org/uniprot/A0A6Q8PGN9> , <https://identifiers.org/uniprot/A0A6Q8PGV1> , <https://identifiers.org/uniprot/C9JAM9> , <https://identifiers.org/uniprot/C9J951> , <https://identifiers.org/uniprot/P42336> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4357_r140180/DataNode/dea4c> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A6Q8PGN9> , <http://purl.uniprot.org/uniprot/A0A6Q8PGV1> , <http://purl.uniprot.org/uniprot/P42336> , <http://purl.uniprot.org/uniprot/C9JAM9> , <http://purl.uniprot.org/uniprot/A0A2R8Y2F6> , <http://purl.uniprot.org/uniprot/C9J951> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/5290> .

<https://identifiers.org/wikipathways/WP4357>
        pav:hasVersion  <https://identifiers.org/wikipathways/WP4357_r140180> .

<https://identifiers.org/ncbigene/7965>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "P38" ;
        dc:identifier       <https://identifiers.org/ncbigene/7965> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "7965" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4357_r140180/Complex/a7754> , <https://identifiers.org/wikipathways/WP4357_r140180> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000106305> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/7965> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/AIMP2> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A024QZY1> , <https://identifiers.org/uniprot/Q13155> , <https://identifiers.org/uniprot/F8WCL2> , <https://identifiers.org/uniprot/A8MU58> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4357_r140180/DataNode/b06bd> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A8MU58> , <http://purl.uniprot.org/uniprot/Q13155> , <http://purl.uniprot.org/uniprot/F8WCL2> , <http://purl.uniprot.org/uniprot/A0A024QZY1> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/7965> .

<https://identifiers.org/ncbigene/1728>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "NQO1" ;
        dc:identifier       <https://identifiers.org/ncbigene/1728> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "1728" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4357_r140180/Complex/dc9de> , <https://identifiers.org/wikipathways/WP4357_r140180> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000181019> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/1728> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/NQO1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/H3BRK3> , <https://identifiers.org/uniprot/H3BNV2> , <https://identifiers.org/uniprot/P15559> , <https://identifiers.org/uniprot/B4DLR8> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4357_r140180/DataNode/f553c> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/H3BNV2> , <http://purl.uniprot.org/uniprot/H3BRK3> , <http://purl.uniprot.org/uniprot/P15559> , <http://purl.uniprot.org/uniprot/B4DLR8> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/1728> .

<http://rdf.wikipathways.org/Pathway/WP4357_r140180/Complex/a7754>
        rdf:type          wp:Complex , wp:DataNode ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4357_r140180> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4357_r140180/Group/a7754> ;
        wp:participants   <https://identifiers.org/ncbigene/5578> , <https://identifiers.org/ncbigene/7965> , <https://identifiers.org/ncbigene/5599> , <https://identifiers.org/ncbigene/2048> .

<https://identifiers.org/ensembl/ENSG00000197122>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "SRC" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000197122> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000197122" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4357_r140180/Complex/d4421> , <http://rdf.wikipathways.org/Pathway/WP4357_r140180/Complex/c2358> , <https://identifiers.org/wikipathways/WP4357_r140180> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000197122> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/6714> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/SRC> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A8I5KYU4> , <https://identifiers.org/uniprot/P12931> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q424737> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4357_r140180/DataNode/ec035> , <http://rdf.wikipathways.org/Pathway/WP4357_r140180/DataNode/cae04> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A8I5KYU4> , <http://purl.uniprot.org/uniprot/P12931> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000197122> .

<https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=png&pwTitle=Pathway:WP4357&oldid=140180>
        rdf:type        foaf:Image ;
        dcterms:format  "image/png" .

<https://identifiers.org/ensembl/ENSG00000151012>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "SLC7A11" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000151012> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000151012" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4357_r140180/Complex/dc9de> , <https://identifiers.org/wikipathways/WP4357_r140180> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000151012> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/23657> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/SLC7A11> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/H0Y9F9> , <https://identifiers.org/uniprot/Q9UPY5> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18037569> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4357_r140180/DataNode/a1b6d> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q9UPY5> , <http://purl.uniprot.org/uniprot/H0Y9F9> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000151012> .

<https://identifiers.org/ncbigene/1051>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "CEBPB" ;
        dc:identifier       <https://identifiers.org/ncbigene/1051> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "1051" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4357_r140180/WP/Interaction/bd859> , <https://identifiers.org/wikipathways/WP4357_r140180> , <http://rdf.wikipathways.org/Pathway/WP4357_r140180/WP/Interaction/bff9c> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000172216> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/1051> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/CEBPB> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/P17676> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4357_r140180/DataNode/b3620> , <http://rdf.wikipathways.org/Pathway/WP4357_r140180/DataNode/c9ebb> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P17676> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/1051> .

<https://identifiers.org/ensembl/ENSG00000171105>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "INSR" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000171105> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000171105" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4357_r140180> , <http://rdf.wikipathways.org/Pathway/WP4357_r140180/WP/Interaction/idd08f0d74> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000171105> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/3643> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/INSR> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/P06213> , <https://identifiers.org/uniprot/M0R3E6> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q14863356> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4357_r140180/DataNode/fd069> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/M0R3E6> , <http://purl.uniprot.org/uniprot/P06213> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000171105> .

<https://identifiers.org/ensembl/ENSG00000100387>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "RBX1" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000100387> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000100387" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4357_r140180/Complex/f0186> , <http://rdf.wikipathways.org/Pathway/WP4357_r140180/Complex/fd81c> , <https://identifiers.org/wikipathways/WP4357_r140180> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000100387> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/9978> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/RBX1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/P62877> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18034928> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4357_r140180/DataNode/c33b5> , <http://rdf.wikipathways.org/Pathway/WP4357_r140180/DataNode/d4a6f> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P62877> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000100387> .

<http://rdf.wikipathways.org/Pathway/WP4357_r140180/Complex/f0186>
        rdf:type                       wp:DataNode , wp:Complex ;
        dcterms:bibliographicCitation  <https://identifiers.org/pubmed/23434765> ;
        dcterms:isPartOf               <https://identifiers.org/wikipathways/WP4357_r140180> ;
        dcterms:references             <https://identifiers.org/pubmed/23434765> ;
        wp:isAbout                     <http://rdf.wikipathways.org/Pathway/WP4357_r140180/Group/f0186> ;
        wp:participants                <https://identifiers.org/ensembl/ENSG00000100387> , <https://identifiers.org/ensembl/ENSG00000036257> , <https://identifiers.org/ncbigene/4780> , <https://identifiers.org/ncbigene/9817> .

<http://rdf.wikipathways.org/Pathway/WP4357_r140180/Complex/fd81c>
        rdf:type          wp:Complex , wp:DataNode ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4357_r140180> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4357_r140180/Group/fd81c> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000036257> , <https://identifiers.org/ensembl/ENSG00000100387> , <https://identifiers.org/ncbigene/9817> .

<https://identifiers.org/ncbigene/2939>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "GSTA2" ;
        dc:identifier       <https://identifiers.org/ncbigene/2939> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "2939" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4357_r140180/Complex/dc9de> , <https://identifiers.org/wikipathways/WP4357_r140180> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000244067> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/2939> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/GSTA2> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/P09210> , <https://identifiers.org/uniprot/A0A140VKE2> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4357_r140180/DataNode/dfa5a> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P09210> , <http://purl.uniprot.org/uniprot/A0A140VKE2> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/2939> .

obo:NCBITaxon_9606  obo:NCIT_C179773  "9606" .

<http://rdf.wikipathways.org/Pathway/WP4357_r140180/WP/Interaction/id8704cb60>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4357_r140180> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4357_r140180/Interaction/id8704cb60> ;
        wp:participants   <https://identifiers.org/ncbigene/4780> ;
        wp:source         <https://identifiers.org/ncbigene/4780> ;
        wp:target         <https://identifiers.org/ncbigene/4780> .

<http://rdf.wikipathways.org/Pathway/WP4357_r140180/WP/Interaction/bff9c>
        rdf:type            wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4357_r140180> ;
        dcterms:references  <https://identifiers.org/pubmed/14570043> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4357_r140180/Interaction/bff9c> ;
        wp:participants     <https://identifiers.org/ncbigene/1051> , <https://identifiers.org/ncbigene/5290> ;
        wp:source           <https://identifiers.org/ncbigene/5290> ;
        wp:target           <https://identifiers.org/ncbigene/1051> .

<https://identifiers.org/ncbigene/2048>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "ERK" ;
        dc:identifier       <https://identifiers.org/ncbigene/2048> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "2048" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4357_r140180/Complex/a7754> , <https://identifiers.org/wikipathways/WP4357_r140180> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000133216> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/2048> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/EPHB2> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q6NVW1> , <https://identifiers.org/uniprot/P29323> , <https://identifiers.org/uniprot/B1AKC9> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4357_r140180/DataNode/dbe12> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q6NVW1> , <http://purl.uniprot.org/uniprot/B1AKC9> , <http://purl.uniprot.org/uniprot/P29323> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/2048> .

<https://identifiers.org/ncbigene/3162>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "HO-1" ;
        dc:identifier       <https://identifiers.org/ncbigene/3162> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "3162" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4357_r140180> , <http://rdf.wikipathways.org/Pathway/WP4357_r140180/Complex/dc9de> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000100292> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/3162> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/HMOX1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/B1AHA8> , <https://identifiers.org/uniprot/A0A7I2YQL9> , <https://identifiers.org/uniprot/Q6FH11> , <https://identifiers.org/uniprot/A0A7I2V3M0> , <https://identifiers.org/uniprot/A0A7I2V277> , <https://identifiers.org/uniprot/A0A7I2V3I1> , <https://identifiers.org/uniprot/P09601> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4357_r140180/DataNode/d4c77> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A7I2V277> , <http://purl.uniprot.org/uniprot/A0A7I2V3M0> , <http://purl.uniprot.org/uniprot/A0A7I2YQL9> , <http://purl.uniprot.org/uniprot/A0A7I2V3I1> , <http://purl.uniprot.org/uniprot/B1AHA8> , <http://purl.uniprot.org/uniprot/Q6FH11> , <http://purl.uniprot.org/uniprot/P09601> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/3162> .

<https://identifiers.org/ensembl/ENSG00000010810>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "FYN" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000010810> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000010810" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4357_r140180/Complex/d4421> , <https://identifiers.org/wikipathways/WP4357_r140180> , <http://rdf.wikipathways.org/Pathway/WP4357_r140180/Complex/c2358> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000010810> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/2534> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/FYN> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/E5RI25> , <https://identifiers.org/uniprot/E5RFM0> , <https://identifiers.org/uniprot/E5RFM4> , <https://identifiers.org/uniprot/P06241> , <https://identifiers.org/uniprot/E5RFS5> , <https://identifiers.org/uniprot/E5RHX7> , <https://identifiers.org/uniprot/E5RGM6> , <https://identifiers.org/uniprot/E5RGT0> , <https://identifiers.org/uniprot/E5RIX5> , <https://identifiers.org/uniprot/E5RK23> , <https://identifiers.org/uniprot/E5RFM6> , <https://identifiers.org/uniprot/E5RJX7> , <https://identifiers.org/uniprot/E5RHF7> , <https://identifiers.org/uniprot/E5RH71> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18024903> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4357_r140180/DataNode/a2105> , <http://rdf.wikipathways.org/Pathway/WP4357_r140180/DataNode/df177> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/E5RGM6> , <http://purl.uniprot.org/uniprot/E5RHF7> , <http://purl.uniprot.org/uniprot/E5RFM6> , <http://purl.uniprot.org/uniprot/E5RIX5> , <http://purl.uniprot.org/uniprot/E5RFM0> , <http://purl.uniprot.org/uniprot/P06241> , <http://purl.uniprot.org/uniprot/E5RK23> , <http://purl.uniprot.org/uniprot/E5RFS5> , <http://purl.uniprot.org/uniprot/E5RFM4> , <http://purl.uniprot.org/uniprot/E5RHX7> , <http://purl.uniprot.org/uniprot/E5RGT0> , <http://purl.uniprot.org/uniprot/E5RJX7> , <http://purl.uniprot.org/uniprot/E5RH71> , <http://purl.uniprot.org/uniprot/E5RI25> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000010810> .

<https://identifiers.org/pubmed/23434765>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "23434765" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4357_r140180/Complex/f0186> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/23434765> .

<https://identifiers.org/ncbigene/5599>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "JNK" ;
        dc:identifier       <https://identifiers.org/ncbigene/5599> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "5599" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4357_r140180> , <http://rdf.wikipathways.org/Pathway/WP4357_r140180/Complex/a7754> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000107643> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/5599> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/MAPK8> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A3B3IRW7> , <https://identifiers.org/uniprot/C9J762> , <https://identifiers.org/uniprot/A1L4K2> , <https://identifiers.org/uniprot/C9JWQ4> , <https://identifiers.org/uniprot/P45983> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4357_r140180/DataNode/a859f> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/C9JWQ4> , <http://purl.uniprot.org/uniprot/C9J762> , <http://purl.uniprot.org/uniprot/A0A3B3IRW7> , <http://purl.uniprot.org/uniprot/P45983> , <http://purl.uniprot.org/uniprot/A1L4K2> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/5599> .

<http://rdf.wikipathways.org/Pathway/WP4357_r140180/WP/Interaction/bd859>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4357_r140180> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4357_r140180/Interaction/bd859> ;
        wp:participants   <https://identifiers.org/ncbigene/1051> ;
        wp:source         <https://identifiers.org/ncbigene/1051> ;
        wp:target         <https://identifiers.org/ncbigene/1051> .

<http://rdf.wikipathways.org/Pathway/WP4357_r140180/Complex/d4421>
        rdf:type          wp:Complex , wp:DataNode ;
        dcterms:isPartOf  <http://rdf.wikipathways.org/Pathway/WP4357_r140180/WP/Interaction/id96cf4eb> , <https://identifiers.org/wikipathways/WP4357_r140180> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4357_r140180/Group/d4421> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000197122> , <https://identifiers.org/ensembl/ENSG00000176105> , <https://identifiers.org/ensembl/ENSG00000010810> .

<https://identifiers.org/pmc/PMC9116376>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed Central" ;
        dcterms:identifier  "PMC9116376" ;
        cito:cites          <https://identifiers.org/wikipathways/WP4357> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/PMC9116376> .

<https://identifiers.org/ncbigene/4780>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "NRF2" ;
        dc:identifier       <https://identifiers.org/ncbigene/4780> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "4780" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4357_r140180/WP/Interaction/id8704cb60> , <https://identifiers.org/wikipathways/WP4357_r140180> , <http://rdf.wikipathways.org/Pathway/WP4357_r140180/Complex/f0186> , <http://rdf.wikipathways.org/Pathway/WP4357_r140180/WP/Interaction/bcfe7> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000116044> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/4780> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/NFE2L2> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A8V8TNS1> , <https://identifiers.org/uniprot/A0A8V8TN41> , <https://identifiers.org/uniprot/A0A8V8TN31> , <https://identifiers.org/uniprot/A0A8V8TNI6> , <https://identifiers.org/uniprot/A0A8V8TN51> , <https://identifiers.org/uniprot/A0A8V8TNM5> , <https://identifiers.org/uniprot/A0A8V8TPT8> , <https://identifiers.org/uniprot/A0A8V8TN14> , <https://identifiers.org/uniprot/A0A8V8TNQ8> , <https://identifiers.org/uniprot/A0A8V8TNJ6> , <https://identifiers.org/uniprot/C9J1A8> , <https://identifiers.org/uniprot/A0A8V8TN85> , <https://identifiers.org/uniprot/A0A8V8TPC8> , <https://identifiers.org/uniprot/K7EIW5> , <https://identifiers.org/uniprot/Q16236> , <https://identifiers.org/uniprot/C9J0Y1> , <https://identifiers.org/uniprot/A0A8V8TPA8> , <https://identifiers.org/uniprot/A0A8V8TPN5> , <https://identifiers.org/uniprot/A0A8V8TPM0> , <https://identifiers.org/uniprot/A0A8V8TQ20> , <https://identifiers.org/uniprot/A0A8V8TPL6> , <https://identifiers.org/uniprot/A0A8V8TN40> , <https://identifiers.org/uniprot/A0A8V8TPF4> , <https://identifiers.org/uniprot/A0A8V8TPX0> , <https://identifiers.org/uniprot/A0A8V8TND9> , <https://identifiers.org/uniprot/A0A8V8TNM0> , <https://identifiers.org/uniprot/K7ER33> , <https://identifiers.org/uniprot/H7C498> , <https://identifiers.org/uniprot/A0A8V8TPF0> , <https://identifiers.org/uniprot/A0A8V8TPI5> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4357_r140180/DataNode/e9e98> , <http://rdf.wikipathways.org/Pathway/WP4357_r140180/DataNode/b2519> , <http://rdf.wikipathways.org/Pathway/WP4357_r140180/DataNode/b5bb9> , <http://rdf.wikipathways.org/Pathway/WP4357_r140180/DataNode/ac76f> , <http://rdf.wikipathways.org/Pathway/WP4357_r140180/DataNode/b68db> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A8V8TPC8> , <http://purl.uniprot.org/uniprot/A0A8V8TNQ8> , <http://purl.uniprot.org/uniprot/A0A8V8TNI6> , <http://purl.uniprot.org/uniprot/A0A8V8TPA8> , <http://purl.uniprot.org/uniprot/A0A8V8TN85> , <http://purl.uniprot.org/uniprot/A0A8V8TQ20> , <http://purl.uniprot.org/uniprot/A0A8V8TN31> , <http://purl.uniprot.org/uniprot/A0A8V8TNM5> , <http://purl.uniprot.org/uniprot/A0A8V8TPF0> , <http://purl.uniprot.org/uniprot/A0A8V8TPI5> , <http://purl.uniprot.org/uniprot/A0A8V8TNS1> , <http://purl.uniprot.org/uniprot/A0A8V8TPT8> , <http://purl.uniprot.org/uniprot/A0A8V8TPL6> , <http://purl.uniprot.org/uniprot/C9J0Y1> , <http://purl.uniprot.org/uniprot/K7EIW5> , <http://purl.uniprot.org/uniprot/A0A8V8TNJ6> , <http://purl.uniprot.org/uniprot/A0A8V8TN14> , <http://purl.uniprot.org/uniprot/H7C498> , <http://purl.uniprot.org/uniprot/A0A8V8TNM0> , <http://purl.uniprot.org/uniprot/A0A8V8TND9> , <http://purl.uniprot.org/uniprot/A0A8V8TPX0> , <http://purl.uniprot.org/uniprot/A0A8V8TPM0> , <http://purl.uniprot.org/uniprot/A0A8V8TN51> , <http://purl.uniprot.org/uniprot/C9J1A8> , <http://purl.uniprot.org/uniprot/A0A8V8TN41> , <http://purl.uniprot.org/uniprot/A0A8V8TPF4> , <http://purl.uniprot.org/uniprot/A0A8V8TN40> , <http://purl.uniprot.org/uniprot/K7ER33> , <http://purl.uniprot.org/uniprot/A0A8V8TPN5> , <http://purl.uniprot.org/uniprot/Q16236> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/4780> .

<https://identifiers.org/ncbigene/5578>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "PKC" ;
        dc:identifier       <https://identifiers.org/ncbigene/5578> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "5578" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4357_r140180> , <http://rdf.wikipathways.org/Pathway/WP4357_r140180/Complex/a7754> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000154229> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/5578> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/PRKCA> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/L7RSM7> , <https://identifiers.org/uniprot/J3KN97> , <https://identifiers.org/uniprot/P17252> , <https://identifiers.org/uniprot/J3KRN5> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4357_r140180/DataNode/a62fe> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P17252> , <http://purl.uniprot.org/uniprot/J3KRN5> , <http://purl.uniprot.org/uniprot/J3KN97> , <http://purl.uniprot.org/uniprot/L7RSM7> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/5578> .

<https://identifiers.org/pubmed/14570043>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "14570043" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4357_r140180/WP/Interaction/bff9c> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/14570043> .

<http://rdf.wikipathways.org/Pathway/WP4357_r140180/WP/Interaction/bcfe7>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4357_r140180> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4357_r140180/Interaction/bcfe7> ;
        wp:participants   <https://identifiers.org/ncbigene/4780> ;
        wp:source         <https://identifiers.org/ncbigene/4780> ;
        wp:target         <https://identifiers.org/ncbigene/4780> .

<https://identifiers.org/ensembl/ENSG00000082701>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "GSK3B" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000082701> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000082701" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4357_r140180/WP/Interaction/idd08f0d74> , <https://identifiers.org/wikipathways/WP4357_r140180> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000082701> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/2932> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/GSK3B> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A7I2YQK2> , <https://identifiers.org/uniprot/A0A7I2V4X2> , <https://identifiers.org/uniprot/A0A7I2V5P4> , <https://identifiers.org/uniprot/A0A7I2V3S5> , <https://identifiers.org/uniprot/A0A7I2V4F3> , <https://identifiers.org/uniprot/A0A7I2V441> , <https://identifiers.org/uniprot/A0A7I2V675> , <https://identifiers.org/uniprot/A0A7I2V3J4> , <https://identifiers.org/uniprot/A0A7I2V432> , <https://identifiers.org/uniprot/A0A7I2V589> , <https://identifiers.org/uniprot/A0A3B3ITW1> , <https://identifiers.org/uniprot/A0A7I2YQ81> , <https://identifiers.org/uniprot/Q6FI27> , <https://identifiers.org/uniprot/A0A7I2V2N4> , <https://identifiers.org/uniprot/A0A7I2YQK0> , <https://identifiers.org/uniprot/A0A7I2V4X3> , <https://identifiers.org/uniprot/A0A7I2V2I5> , <https://identifiers.org/uniprot/A0A7I2V5B5> , <https://identifiers.org/uniprot/A0A7I2V606> , <https://identifiers.org/uniprot/A0A7I2V3K8> , <https://identifiers.org/uniprot/A0A7I2V2V4> , <https://identifiers.org/uniprot/A0A7I2V5K9> , <https://identifiers.org/uniprot/A0A7I2V5M2> , <https://identifiers.org/uniprot/A0A7I2V3A4> , <https://identifiers.org/uniprot/A0A7I2V2Y0> , <https://identifiers.org/uniprot/A0A7I2YQB0> , <https://identifiers.org/uniprot/A0A7I2V2U4> , <https://identifiers.org/uniprot/A0A7I2V4G2> , <https://identifiers.org/uniprot/A0A7I2V3D8> , <https://identifiers.org/uniprot/A0A7I2V626> , <https://identifiers.org/uniprot/P49841> , <https://identifiers.org/uniprot/A0A7I2YQG6> , <https://identifiers.org/uniprot/A0A7I2V2K7> , <https://identifiers.org/uniprot/A0A7I2V5G5> , <https://identifiers.org/uniprot/A0A7I2V3T3> , <https://identifiers.org/uniprot/A0A7I2V3G9> , <https://identifiers.org/uniprot/A0A7I2YQU1> , <https://identifiers.org/uniprot/A0A7I2V4W7> , <https://identifiers.org/uniprot/A0A7I2V3N7> , <https://identifiers.org/uniprot/A0A7I2V2T2> , <https://identifiers.org/uniprot/A0A7I2V3Z5> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18258585> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4357_r140180/DataNode/be7b8> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A7I2V3D8> , <http://purl.uniprot.org/uniprot/P49841> , <http://purl.uniprot.org/uniprot/A0A7I2V675> , <http://purl.uniprot.org/uniprot/A0A7I2YQK2> , <http://purl.uniprot.org/uniprot/A0A7I2V2U4> , <http://purl.uniprot.org/uniprot/A0A7I2V3G9> , <http://purl.uniprot.org/uniprot/A0A7I2V2T2> , <http://purl.uniprot.org/uniprot/A0A7I2V3N7> , <http://purl.uniprot.org/uniprot/A0A3B3ITW1> , <http://purl.uniprot.org/uniprot/A0A7I2V4X3> , <http://purl.uniprot.org/uniprot/A0A7I2YQG6> , <http://purl.uniprot.org/uniprot/A0A7I2V2N4> , <http://purl.uniprot.org/uniprot/A0A7I2V2V4> , <http://purl.uniprot.org/uniprot/A0A7I2V441> , <http://purl.uniprot.org/uniprot/A0A7I2V4F3> , <http://purl.uniprot.org/uniprot/A0A7I2V3Z5> , <http://purl.uniprot.org/uniprot/Q6FI27> , <http://purl.uniprot.org/uniprot/A0A7I2V3T3> , <http://purl.uniprot.org/uniprot/A0A7I2V3J4> , <http://purl.uniprot.org/uniprot/A0A7I2V4G2> , <http://purl.uniprot.org/uniprot/A0A7I2V4X2> , <http://purl.uniprot.org/uniprot/A0A7I2V2Y0> , <http://purl.uniprot.org/uniprot/A0A7I2V3A4> , <http://purl.uniprot.org/uniprot/A0A7I2V3S5> , <http://purl.uniprot.org/uniprot/A0A7I2V432> , <http://purl.uniprot.org/uniprot/A0A7I2V4W7> , <http://purl.uniprot.org/uniprot/A0A7I2V5M2> , <http://purl.uniprot.org/uniprot/A0A7I2YQB0> , <http://purl.uniprot.org/uniprot/A0A7I2V626> , <http://purl.uniprot.org/uniprot/A0A7I2V589> , <http://purl.uniprot.org/uniprot/A0A7I2V2K7> , <http://purl.uniprot.org/uniprot/A0A7I2V3K8> , <http://purl.uniprot.org/uniprot/A0A7I2YQU1> , <http://purl.uniprot.org/uniprot/A0A7I2V5G5> , <http://purl.uniprot.org/uniprot/A0A7I2V2I5> , <http://purl.uniprot.org/uniprot/A0A7I2V606> , <http://purl.uniprot.org/uniprot/A0A7I2V5K9> , <http://purl.uniprot.org/uniprot/A0A7I2YQ81> , <http://purl.uniprot.org/uniprot/A0A7I2V5B5> , <http://purl.uniprot.org/uniprot/A0A7I2YQK0> , <http://purl.uniprot.org/uniprot/A0A7I2V5P4> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000082701> .

<https://identifiers.org/ncbigene/4094>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "MAF" ;
        dc:identifier       <https://identifiers.org/ncbigene/4094> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "4094" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4357_r140180> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000178573> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/4094> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/MAF> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/O75444> , <https://identifiers.org/uniprot/H3BP11> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4357_r140180/DataNode/d79c3> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/O75444> , <http://purl.uniprot.org/uniprot/H3BP11> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/4094> .

<http://rdf.wikipathways.org/Pathway/WP4357_r140180/ComplexBinding/c2358>
        rdf:type          wp:ComplexBinding , wp:Binding , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4357_r140180> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4357_r140180/Group/c2358> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000197122> , <https://identifiers.org/ensembl/ENSG00000010810> , <https://identifiers.org/ensembl/ENSG00000176105> , <http://rdf.wikipathways.org/Pathway/WP4357_r140180/Complex/c2358> .

<http://rdf.wikipathways.org/Pathway/WP4357_r140180/ComplexBinding/dc9de>
        rdf:type          wp:Interaction , wp:ComplexBinding , wp:Binding ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4357_r140180> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4357_r140180/Group/dc9de> ;
        wp:participants   <http://rdf.wikipathways.org/Pathway/WP4357_r140180/Complex/dc9de> , <https://identifiers.org/ensembl/ENSG00000151012> , <https://identifiers.org/ncbigene/3162> , <https://identifiers.org/ncbigene/2730> , <https://identifiers.org/ncbigene/2939> , <https://identifiers.org/ncbigene/1728> , <https://identifiers.org/ncbigene/2729> .

<https://identifiers.org/pubmed/25514926>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "25514926" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4357_r140180> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/25514926> .

<https://identifiers.org/ensembl/ENSG00000176105>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "YES1" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000176105> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000176105" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4357_r140180/Complex/d4421> , <http://rdf.wikipathways.org/Pathway/WP4357_r140180/Complex/c2358> , <https://identifiers.org/wikipathways/WP4357_r140180> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000176105> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/7525> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/YES1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/J3QRU1> , <https://identifiers.org/uniprot/P07947> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18032403> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4357_r140180/DataNode/aa321> , <http://rdf.wikipathways.org/Pathway/WP4357_r140180/DataNode/b8bc4> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P07947> , <http://purl.uniprot.org/uniprot/J3QRU1> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000176105> .

<http://rdf.wikipathways.org/Pathway/WP4357_r140180/ComplexBinding/a7754>
        rdf:type          wp:Interaction , wp:ComplexBinding , wp:Binding ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4357_r140180> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4357_r140180/Group/a7754> ;
        wp:participants   <https://identifiers.org/ncbigene/7965> , <https://identifiers.org/ncbigene/5599> , <http://rdf.wikipathways.org/Pathway/WP4357_r140180/Complex/a7754> , <https://identifiers.org/ncbigene/2048> , <https://identifiers.org/ncbigene/5578> .

<http://rdf.wikipathways.org/Pathway/WP4357_r140180/Complex/dc9de>
        rdf:type          wp:Complex , wp:DataNode ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4357_r140180> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4357_r140180/Group/dc9de> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000151012> , <https://identifiers.org/ncbigene/2730> , <https://identifiers.org/ncbigene/1728> , <https://identifiers.org/ncbigene/2939> , <https://identifiers.org/ncbigene/3162> , <https://identifiers.org/ncbigene/2729> .

<https://identifiers.org/pmc/PMC11191590>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed Central" ;
        dcterms:identifier  "PMC11191590" ;
        cito:cites          <https://identifiers.org/wikipathways/WP4357> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/PMC11191590> .

<https://identifiers.org/ncbigene/2729>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "GCLC" ;
        dc:identifier       <https://identifiers.org/ncbigene/2729> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "2729" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4357_r140180> , <http://rdf.wikipathways.org/Pathway/WP4357_r140180/Complex/dc9de> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000001084> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/2729> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/GCLC> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/D6RGF8> , <https://identifiers.org/uniprot/A0A0C4DGB2> , <https://identifiers.org/uniprot/P48506> , <https://identifiers.org/uniprot/D6RIT4> , <https://identifiers.org/uniprot/B4E2I4> , <https://identifiers.org/uniprot/E1CEI4> , <https://identifiers.org/uniprot/A0A2R8Y648> , <https://identifiers.org/uniprot/Q14TF0> , <https://identifiers.org/uniprot/A0A2R8YEL6> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4357_r140180/DataNode/cecad> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/E1CEI4> , <http://purl.uniprot.org/uniprot/A0A2R8YEL6> , <http://purl.uniprot.org/uniprot/D6RIT4> , <http://purl.uniprot.org/uniprot/P48506> , <http://purl.uniprot.org/uniprot/Q14TF0> , <http://purl.uniprot.org/uniprot/A0A0C4DGB2> , <http://purl.uniprot.org/uniprot/D6RGF8> , <http://purl.uniprot.org/uniprot/A0A2R8Y648> , <http://purl.uniprot.org/uniprot/B4E2I4> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/2729> .
