@prefix biopax:  <http://www.biopax.org/release/biopax-level3.owl#> .
@prefix cito:    <http://purl.org/spar/cito/> .
@prefix dc:      <http://purl.org/dc/elements/1.1/> .
@prefix dcterms: <http://purl.org/dc/terms/> .
@prefix foaf:    <http://xmlns.com/foaf/0.1/> .
@prefix freq:    <http://purl.org/cld/freq/> .
@prefix gpml:    <http://vocabularies.wikipathways.org/gpml#> .
@prefix obo:     <http://purl.obolibrary.org/obo/> .
@prefix owl:     <http://www.w3.org/2002/07/owl#> .
@prefix pav:     <http://purl.org/pav/> .
@prefix prov:    <http://www.w3.org/ns/prov#> .
@prefix rdf:     <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix rdfs:    <http://www.w3.org/2000/01/rdf-schema#> .
@prefix skos:    <http://www.w3.org/2004/02/skos/core#> .
@prefix void:    <http://rdfs.org/ns/void#> .
@prefix wp:      <http://vocabularies.wikipathways.org/wp#> .
@prefix wprdf:   <http://rdf.wikipathways.org/> .
@prefix xsd:     <http://www.w3.org/2001/XMLSchema#> .

<http://rdf.wikipathways.org/Pathway/WP3655_r142023/WP/Interaction/id67bb1346>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP3655_r142023> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP3655_r142023/Interaction/id67bb1346> ;
        wp:participants   <https://identifiers.org/hgnc.symbol/RHOA> , <https://identifiers.org/hgnc.symbol/TGFB3> ;
        wp:source         <https://identifiers.org/hgnc.symbol/TGFB3> ;
        wp:target         <https://identifiers.org/hgnc.symbol/RHOA> .

<https://identifiers.org/pmc/PMC12106470>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed Central" ;
        dcterms:identifier  "PMC12106470" ;
        cito:cites          <https://identifiers.org/wikipathways/WP3655> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/PMC12106470> .

<https://identifiers.org/hgnc.symbol/TFAP2A>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "TFAP2A" ;
        dc:identifier       <https://identifiers.org/hgnc.symbol/TFAP2A> ;
        dc:source           "HGNC" ;
        dcterms:identifier  "TFAP2A" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP3655_r142023> , <http://rdf.wikipathways.org/Pathway/WP3655_r142023/WP/Interaction/id6b85dc31> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSOANG00000007183> , <https://identifiers.org/ensembl/ENSSSCG00000001036> , <https://identifiers.org/ensembl/ENSG00000137203> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/100049668> , <https://identifiers.org/ncbigene/7020> , <https://identifiers.org/ncbigene/100082770> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/TFAP2A> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A4X1SH61> , <https://identifiers.org/uniprot/C9JXZ2> , <https://identifiers.org/uniprot/A0A287API9> , <https://identifiers.org/uniprot/A0A287B9K7> , <https://identifiers.org/uniprot/F6XY74> , <https://identifiers.org/uniprot/A0A6E1XE14> , <https://identifiers.org/uniprot/A0A4X1SH68> , <https://identifiers.org/uniprot/H7C5E5> , <https://identifiers.org/uniprot/A0A4X1SHQ0> , <https://identifiers.org/uniprot/F8WDC8> , <https://identifiers.org/uniprot/C9J6N8> , <https://identifiers.org/uniprot/H7C4N4> , <https://identifiers.org/uniprot/F8WEX2> , <https://identifiers.org/uniprot/F6XY47> , <https://identifiers.org/uniprot/A0A480QU30> , <https://identifiers.org/uniprot/C1K3N0> , <https://identifiers.org/uniprot/P05549> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP3655_r142023/DataNode/b8de4> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A287B9K7> , <http://purl.uniprot.org/uniprot/A0A480QU30> , <http://purl.uniprot.org/uniprot/A0A4X1SHQ0> , <http://purl.uniprot.org/uniprot/H7C4N4> , <http://purl.uniprot.org/uniprot/F8WEX2> , <http://purl.uniprot.org/uniprot/F8WDC8> , <http://purl.uniprot.org/uniprot/A0A4X1SH68> , <http://purl.uniprot.org/uniprot/F6XY47> , <http://purl.uniprot.org/uniprot/A0A4X1SH61> , <http://purl.uniprot.org/uniprot/P05549> , <http://purl.uniprot.org/uniprot/A0A6E1XE14> , <http://purl.uniprot.org/uniprot/F6XY74> , <http://purl.uniprot.org/uniprot/C1K3N0> , <http://purl.uniprot.org/uniprot/C9JXZ2> , <http://purl.uniprot.org/uniprot/A0A287API9> , <http://purl.uniprot.org/uniprot/C9J6N8> , <http://purl.uniprot.org/uniprot/H7C5E5> ;
        foaf:page           <https://www.genenames.org/data/gene-symbol-report/#!/symbol/TFAP2A> .

<https://identifiers.org/pubmed/23008150>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "23008150" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP3655_r142023> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/23008150> .

<https://identifiers.org/wikipathways/WP428>
        rdf:type            wp:Pathway , wp:DataNode ;
        rdfs:label          "WNT signaling" ;
        dc:identifier       <https://identifiers.org/wikipathways/WP428> ;
        dc:source           "WikiPathways" ;
        dcterms:identifier  "WP428" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP3655_r142023> , <http://rdf.wikipathways.org/Pathway/WP3655_r142023/WP/Interaction/id15b3d8a7> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP3655_r142023/DataNode/c0888> ;
        foaf:page           <https://www.wikipathways.org/instance/WP428> .

<https://identifiers.org/wikipathways/WP3655>
        pav:hasVersion  <https://identifiers.org/wikipathways/WP3655_r142023> .

<https://identifiers.org/hgnc.symbol/ARHGAP29>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "ARHGAP29" ;
        dc:identifier       <https://identifiers.org/hgnc.symbol/ARHGAP29> ;
        dc:source           "HGNC" ;
        dcterms:identifier  "ARHGAP29" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP3655_r142023/WP/Interaction/ida367b569> , <https://identifiers.org/wikipathways/WP3655_r142023> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSSSCG00000006889> , <https://identifiers.org/ensembl/ENSG00000137962> , <https://identifiers.org/ensembl/ENSCAFG00845015082> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/9411> , <https://identifiers.org/ncbigene/105378858> , <https://identifiers.org/ncbigene/479940> , <https://identifiers.org/ncbigene/100152734> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/ARHGAP29> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/F1S540> , <https://identifiers.org/uniprot/Q52LW3> , <https://identifiers.org/uniprot/A0A4X1TZX6> , <https://identifiers.org/uniprot/F8VWZ8> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP3655_r142023/DataNode/a8d97> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/F1S540> , <http://purl.uniprot.org/uniprot/F8VWZ8> , <http://purl.uniprot.org/uniprot/A0A4X1TZX6> , <http://purl.uniprot.org/uniprot/Q52LW3> ;
        foaf:page           <https://www.genenames.org/data/gene-symbol-report/#!/symbol/ARHGAP29> .

<http://rdf.wikipathways.org/Pathway/WP3655_r142023/ComplexBinding/a1bd3>
        rdf:type          wp:ComplexBinding , wp:Binding , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP3655_r142023> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP3655_r142023/Group/a1bd3> ;
        wp:participants   <https://identifiers.org/hmdb/HMDB0001440> , <https://identifiers.org/hgnc.symbol/RHOA> , <http://rdf.wikipathways.org/Pathway/WP3655_r142023/Complex/a1bd3> .

<https://identifiers.org/hgnc.symbol/ARHGEF2>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "GEF" ;
        dc:identifier       <https://identifiers.org/hgnc.symbol/ARHGEF2> ;
        dc:source           "HGNC" ;
        dcterms:identifier  "ARHGEF2" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP3655_r142023> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSSSCG00000006502> , <https://identifiers.org/ensembl/ENSOANG00000047409> , <https://identifiers.org/ensembl/ENSG00000116584> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/100145887> , <https://identifiers.org/ncbigene/9181> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/ARHGEF2> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A1Y8EN19> , <https://identifiers.org/uniprot/Q92974> , <https://identifiers.org/uniprot/A0A287ATI0> , <https://identifiers.org/uniprot/V9GYF0> , <https://identifiers.org/uniprot/A0A5F9ZI21> , <https://identifiers.org/uniprot/A0A287ACU3> , <https://identifiers.org/uniprot/A0A8Q3SIV8> , <https://identifiers.org/uniprot/V9GY94> , <https://identifiers.org/uniprot/A0A287APM0> , <https://identifiers.org/uniprot/V9GYG5> , <https://identifiers.org/uniprot/A0A8Q3SIN5> , <https://identifiers.org/uniprot/V9GYF5> , <https://identifiers.org/uniprot/V9GZ58> , <https://identifiers.org/uniprot/F1RLP5> , <https://identifiers.org/uniprot/A0A287B6A9> , <https://identifiers.org/uniprot/A0A287A2N8> , <https://identifiers.org/uniprot/V9GYM8> , <https://identifiers.org/uniprot/V9GZ14> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP3655_r142023/DataNode/b2267> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A287ACU3> , <http://purl.uniprot.org/uniprot/A0A8Q3SIN5> , <http://purl.uniprot.org/uniprot/A0A8Q3SIV8> , <http://purl.uniprot.org/uniprot/A0A287ATI0> , <http://purl.uniprot.org/uniprot/A0A1Y8EN19> , <http://purl.uniprot.org/uniprot/V9GYM8> , <http://purl.uniprot.org/uniprot/A0A5F9ZI21> , <http://purl.uniprot.org/uniprot/V9GYF0> , <http://purl.uniprot.org/uniprot/V9GZ58> , <http://purl.uniprot.org/uniprot/A0A287A2N8> , <http://purl.uniprot.org/uniprot/V9GYG5> , <http://purl.uniprot.org/uniprot/A0A287APM0> , <http://purl.uniprot.org/uniprot/Q92974> , <http://purl.uniprot.org/uniprot/F1RLP5> , <http://purl.uniprot.org/uniprot/V9GY94> , <http://purl.uniprot.org/uniprot/V9GZ14> , <http://purl.uniprot.org/uniprot/A0A287B6A9> , <http://purl.uniprot.org/uniprot/V9GYF5> ;
        foaf:page           <https://www.genenames.org/data/gene-symbol-report/#!/symbol/ARHGEF2> .

<http://rdf.wikipathways.org/Pathway/WP3655_r142023/WP/Interaction/idb4368bec>
        rdf:type          wp:Inhibition , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP3655_r142023> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP3655_r142023/Interaction/idb4368bec> ;
        wp:participants   <https://identifiers.org/hgnc.symbol/TP63> , <https://identifiers.org/hgnc.symbol/IRF6> ;
        wp:source         <https://identifiers.org/hgnc.symbol/IRF6> ;
        wp:target         <https://identifiers.org/hgnc.symbol/TP63> .

<http://rdf.wikipathways.org/Pathway/WP3655_r142023/Complex/a1bd3>
        rdf:type          wp:Complex , wp:DataNode ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP3655_r142023> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP3655_r142023/Group/a1bd3> ;
        wp:participants   <https://identifiers.org/hmdb/HMDB0001440> , <https://identifiers.org/hgnc.symbol/RHOA> .

<https://identifiers.org/hgnc.symbol/TGFB3>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "TGFB3" ;
        dc:identifier       <https://identifiers.org/hgnc.symbol/TGFB3> ;
        dc:source           "HGNC" ;
        dcterms:identifier  "TGFB3" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP3655_r142023/WP/Interaction/id67bb1346> , <https://identifiers.org/wikipathways/WP3655_r142023> , <http://rdf.wikipathways.org/Pathway/WP3655_r142023/WP/Interaction/id69972f6c> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSSSCG00000002385> , <https://identifiers.org/ensembl/ENSG00000119699> , <https://identifiers.org/ensembl/ENSOANG00000046243> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/397400> , <https://identifiers.org/ncbigene/7043> , <https://identifiers.org/ncbigene/100074840> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/TGFB3> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A5YM40> , <https://identifiers.org/uniprot/A0A6Q8PGK5> , <https://identifiers.org/uniprot/A0A8D1N627> , <https://identifiers.org/uniprot/K7GSJ9> , <https://identifiers.org/uniprot/P10600> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP3655_r142023/DataNode/e8c22> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P10600> , <http://purl.uniprot.org/uniprot/A0A6Q8PGK5> , <http://purl.uniprot.org/uniprot/A5YM40> , <http://purl.uniprot.org/uniprot/K7GSJ9> , <http://purl.uniprot.org/uniprot/A0A8D1N627> ;
        foaf:page           <https://www.genenames.org/data/gene-symbol-report/#!/symbol/TGFB3> .

<https://identifiers.org/hmdb/HMDB0001440>
        rdf:type            wp:Metabolite , wp:DataNode ;
        rdfs:label          "GTP" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/HAAZLUGHYHWQIW-KVQBGUIXSA-N> ;
        dc:identifier       <https://identifiers.org/hmdb/HMDB0001440> ;
        dc:source           "HMDB" ;
        dcterms:identifier  "HMDB0001440" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP3655_r142023/Complex/a1bd3> , <https://identifiers.org/wikipathways/WP3655_r142023> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:16497> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/58613> ;
        wp:bdbHmdb          <https://identifiers.org/hmdb/HMDB0001440> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/HAAZLUGHYHWQIW-KVQBGUIXSA-N> ;
        wp:bdbKeggCompound  <https://identifiers.org/kegg.compound/C00286> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID65103> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q424586> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP3655_r142023/DataNode/d8cd5> ;
        foaf:page           <http://www.hmdb.ca/metabolites/HMDB0001440> .

<https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=png&pwTitle=Pathway:WP3655&oldid=142023>
        rdf:type        foaf:Image ;
        dcterms:format  "image/png" .

<https://identifiers.org/hgnc.symbol/RHOA>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "RHOA" ;
        dc:identifier       <https://identifiers.org/hgnc.symbol/RHOA> ;
        dc:source           "HGNC" ;
        dcterms:identifier  "RHOA" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP3655_r142023/WP/Interaction/id67bb1346> , <http://rdf.wikipathways.org/Pathway/WP3655_r142023/Complex/b236e> , <http://rdf.wikipathways.org/Pathway/WP3655_r142023/WP/Interaction/id15b3d8a7> , <https://identifiers.org/wikipathways/WP3655_r142023> , <http://rdf.wikipathways.org/Pathway/WP3655_r142023/Complex/a1bd3> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSSSCG00000022080> , <https://identifiers.org/ensembl/ENSG00000067560> , <https://identifiers.org/ensembl/ENSOANG00000013807> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/387> , <https://identifiers.org/ncbigene/100073519> , <https://identifiers.org/ncbigene/396849> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/RHOA> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/C9JNR4> , <https://identifiers.org/uniprot/A0A7I2YQV1> , <https://identifiers.org/uniprot/A0A7I2V3G1> , <https://identifiers.org/uniprot/A0A024R324> , <https://identifiers.org/uniprot/C9JX21> , <https://identifiers.org/uniprot/A0A7I2V5E6> , <https://identifiers.org/uniprot/P61586> , <https://identifiers.org/uniprot/I3LVS7> , <https://identifiers.org/uniprot/F7DKX6> , <https://identifiers.org/uniprot/A0A4X1ST20> , <https://identifiers.org/uniprot/C9JRM1> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP3655_r142023/DataNode/a4e9f> , <http://rdf.wikipathways.org/Pathway/WP3655_r142023/DataNode/d0426> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/I3LVS7> , <http://purl.uniprot.org/uniprot/A0A024R324> , <http://purl.uniprot.org/uniprot/C9JRM1> , <http://purl.uniprot.org/uniprot/C9JX21> , <http://purl.uniprot.org/uniprot/A0A4X1ST20> , <http://purl.uniprot.org/uniprot/A0A7I2V5E6> , <http://purl.uniprot.org/uniprot/A0A7I2YQV1> , <http://purl.uniprot.org/uniprot/A0A7I2V3G1> , <http://purl.uniprot.org/uniprot/C9JNR4> , <http://purl.uniprot.org/uniprot/P61586> , <http://purl.uniprot.org/uniprot/F7DKX6> ;
        foaf:page           <https://www.genenames.org/data/gene-symbol-report/#!/symbol/RHOA> .

<http://rdf.wikipathways.org/Pathway/WP3655_r142023/WP/Interaction/ida367b569>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP3655_r142023> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP3655_r142023/Interaction/ida367b569> ;
        wp:participants   <https://identifiers.org/hgnc.symbol/ARHGAP29> , <https://identifiers.org/hgnc.symbol/IRF6> ;
        wp:source         <https://identifiers.org/hgnc.symbol/IRF6> ;
        wp:target         <https://identifiers.org/hgnc.symbol/ARHGAP29> .

<http://rdf.wikipathways.org/Pathway/WP3655_r142023/WP/Interaction/id69972f6c>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP3655_r142023> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP3655_r142023/Interaction/id69972f6c> ;
        wp:participants   <https://identifiers.org/hgnc.symbol/IRF6> , <https://identifiers.org/hgnc.symbol/TGFB3> ;
        wp:source         <https://identifiers.org/hgnc.symbol/TGFB3> ;
        wp:target         <https://identifiers.org/hgnc.symbol/IRF6> .

<https://identifiers.org/hgnc.symbol/TP63>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "TP63" ;
        dc:identifier       <https://identifiers.org/hgnc.symbol/TP63> ;
        dc:source           "HGNC" ;
        dcterms:identifier  "TP63" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP3655_r142023/WP/Interaction/idb4368bec> , <https://identifiers.org/wikipathways/WP3655_r142023> , <http://rdf.wikipathways.org/Pathway/WP3655_r142023/WP/Interaction/id8c81ce6b> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSOANG00000013795> , <https://identifiers.org/ensembl/ENSG00000073282> , <https://identifiers.org/ensembl/ENSSSCG00000025592> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/100081838> , <https://identifiers.org/ncbigene/8626> , <https://identifiers.org/ncbigene/100625258> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/TP63> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A8D0N5U6> , <https://identifiers.org/uniprot/A0A4X1UBD5> , <https://identifiers.org/uniprot/A0A287BET2> , <https://identifiers.org/uniprot/A0A480T7V4> , <https://identifiers.org/uniprot/A0A481AE05> , <https://identifiers.org/uniprot/A0A0S2Z4N6> , <https://identifiers.org/uniprot/A0A5G2QYI3> , <https://identifiers.org/uniprot/A0A4X1U8X5> , <https://identifiers.org/uniprot/A0A8D1EWR0> , <https://identifiers.org/uniprot/I3LPD4> , <https://identifiers.org/uniprot/C9JW72> , <https://identifiers.org/uniprot/C9D7D0> , <https://identifiers.org/uniprot/Q9H3D4> , <https://identifiers.org/uniprot/A0A4X1UD52> , <https://identifiers.org/uniprot/A0A5G2Q965> , <https://identifiers.org/uniprot/A0A0S2Z4N5> , <https://identifiers.org/uniprot/A0A4X1UD21> , <https://identifiers.org/uniprot/F7DUR2> , <https://identifiers.org/uniprot/A0A287BN74> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP3655_r142023/DataNode/b9a7c> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/C9JW72> , <http://purl.uniprot.org/uniprot/A0A287BET2> , <http://purl.uniprot.org/uniprot/A0A4X1U8X5> , <http://purl.uniprot.org/uniprot/C9D7D0> , <http://purl.uniprot.org/uniprot/A0A5G2Q965> , <http://purl.uniprot.org/uniprot/Q9H3D4> , <http://purl.uniprot.org/uniprot/A0A4X1UD52> , <http://purl.uniprot.org/uniprot/A0A4X1UBD5> , <http://purl.uniprot.org/uniprot/A0A8D0N5U6> , <http://purl.uniprot.org/uniprot/A0A8D1EWR0> , <http://purl.uniprot.org/uniprot/A0A4X1UD21> , <http://purl.uniprot.org/uniprot/A0A287BN74> , <http://purl.uniprot.org/uniprot/A0A0S2Z4N5> , <http://purl.uniprot.org/uniprot/F7DUR2> , <http://purl.uniprot.org/uniprot/A0A480T7V4> , <http://purl.uniprot.org/uniprot/A0A5G2QYI3> , <http://purl.uniprot.org/uniprot/A0A481AE05> , <http://purl.uniprot.org/uniprot/I3LPD4> , <http://purl.uniprot.org/uniprot/A0A0S2Z4N6> ;
        foaf:page           <https://www.genenames.org/data/gene-symbol-report/#!/symbol/TP63> .

<http://rdf.wikipathways.org/Pathway/WP3655_r142023/Complex/b236e>
        rdf:type          wp:Complex , wp:DataNode ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP3655_r142023> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP3655_r142023/Group/b236e> ;
        wp:participants   <https://identifiers.org/hmdb/HMDB0000960> , <https://identifiers.org/hgnc.symbol/RHOA> .

<https://identifiers.org/hgnc.symbol/IRF6>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "IRF6" ;
        dc:identifier       <https://identifiers.org/hgnc.symbol/IRF6> ;
        dc:source           "HGNC" ;
        dcterms:identifier  "IRF6" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP3655_r142023/WP/Interaction/id8c81ce6b> , <https://identifiers.org/wikipathways/WP3655_r142023> , <http://rdf.wikipathways.org/Pathway/WP3655_r142023/WP/Interaction/ida367b569> , <http://rdf.wikipathways.org/Pathway/WP3655_r142023/WP/Interaction/id6b85dc31> , <http://rdf.wikipathways.org/Pathway/WP3655_r142023/WP/Interaction/id69972f6c> , <http://rdf.wikipathways.org/Pathway/WP3655_r142023/WP/Interaction/idb4368bec> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSGALG00010027212> , <https://identifiers.org/ensembl/ENSG00000117595> , <https://identifiers.org/ensembl/ENSOANG00000013718> , <https://identifiers.org/ensembl/ENSSSCG00000015612> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/419863> , <https://identifiers.org/ncbigene/397521> , <https://identifiers.org/ncbigene/3664> , <https://identifiers.org/ncbigene/100084667> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/IRF6> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/O14896> , <https://identifiers.org/uniprot/F7FV91> , <https://identifiers.org/uniprot/B1AJU4> , <https://identifiers.org/uniprot/E9LK28> , <https://identifiers.org/uniprot/G0Z349> , <https://identifiers.org/uniprot/A0A2R8YHF3> , <https://identifiers.org/uniprot/A0A8Q3WL17> , <https://identifiers.org/uniprot/A0A4X1TG90> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP3655_r142023/DataNode/b1d3c> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/E9LK28> , <http://purl.uniprot.org/uniprot/G0Z349> , <http://purl.uniprot.org/uniprot/A0A8Q3WL17> , <http://purl.uniprot.org/uniprot/O14896> , <http://purl.uniprot.org/uniprot/A0A4X1TG90> , <http://purl.uniprot.org/uniprot/A0A2R8YHF3> , <http://purl.uniprot.org/uniprot/F7FV91> , <http://purl.uniprot.org/uniprot/B1AJU4> ;
        foaf:page           <https://www.genenames.org/data/gene-symbol-report/#!/symbol/IRF6> .

<https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=svg&pwTitle=Pathway:WP3655&oldid=142023>
        rdf:type        foaf:Image ;
        dcterms:format  "image/svg+xml" .

<http://rdf.wikipathways.org/Pathway/WP3655_r142023/WP/Interaction/id15b3d8a7>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP3655_r142023> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP3655_r142023/Interaction/id15b3d8a7> ;
        wp:participants   <https://identifiers.org/hgnc.symbol/RHOA> , <https://identifiers.org/wikipathways/WP428> ;
        wp:source         <https://identifiers.org/wikipathways/WP428> ;
        wp:target         <https://identifiers.org/hgnc.symbol/RHOA> .

<https://identifiers.org/wikipathways/WP3655_r142023>
        rdf:type               skos:Collection , wp:Pathway ;
        dc:identifier          <https://identifiers.org/wikipathways/WP3655> ;
        dc:source              "WikiPathways" ;
        dc:title               "Hypothetical craniofacial development pathway"@en ;
        dcterms:description    "Hypothetical pathway linking cranio-facial development pathway (IRF6, TP63, TFAP2A, and TGFB3) to Rho signaling pathway through ARHGAP29 regulation. Authors of literature suspect that a decrease of ARHGAP29 concentration would result in more active form, Rho-GTP, which would down-regulate cranio-facial development genes. An implication of this active Rho-GTP may be the formation of cleft lip. This pathway is based on figure 4 from Leslie et al." ;
        dcterms:identifier     "WP3655" ;
        dcterms:references     <https://identifiers.org/pubmed/23008150> ;
        cito:cites             <https://identifiers.org/pubmed/23008150> ;
        wp:diseaseOntologyTag  obo:DOID_9296 ;
        wp:isAbout             <http://rdf.wikipathways.org/Pathway/WP3655_r142023> ;
        wp:ontologyTag         obo:PW_0000650 , obo:DOID_9296 , wp:Curation:AnalysisCollection , obo:PW_0000003 ;
        wp:organism            obo:NCBITaxon_9606 ;
        wp:organismName        "Homo sapiens" ;
        wp:pathwayOntologyTag  obo:PW_0000650 , obo:PW_0000003 ;
        foaf:img               <https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=png&pwTitle=Pathway:WP3655&oldid=142023> , <https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=svg&pwTitle=Pathway:WP3655&oldid=142023> ;
        foaf:page              <http://www.wikipathways.org/instance/WP3655_r142023> .

<https://identifiers.org/hmdb/HMDB0000960>
        rdf:type            wp:Metabolite , wp:DataNode ;
        rdfs:label          "GDP" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/CIKGWCTVFSRMJU-KVQBGUIXSA-N> ;
        dc:identifier       <https://identifiers.org/hmdb/HMDB0000960> ;
        dc:source           "HMDB" ;
        dcterms:identifier  "HMDB0000960" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP3655_r142023/Complex/b236e> , <https://identifiers.org/wikipathways/WP3655_r142023> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:28862> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/388359> ;
        wp:bdbHmdb          <https://identifiers.org/hmdb/HMDB0000960> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/CIKGWCTVFSRMJU-KVQBGUIXSA-N> ;
        wp:bdbKeggCompound  <https://identifiers.org/kegg.compound/C00361> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID439220> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q27103932> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP3655_r142023/DataNode/e98ab> ;
        foaf:page           <http://www.hmdb.ca/metabolites/HMDB0000960> .

<http://rdf.wikipathways.org/Pathway/WP3655_r142023/ComplexBinding/b236e>
        rdf:type          wp:ComplexBinding , wp:Binding , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP3655_r142023> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP3655_r142023/Group/b236e> ;
        wp:participants   <https://identifiers.org/hmdb/HMDB0000960> , <https://identifiers.org/hgnc.symbol/RHOA> , <http://rdf.wikipathways.org/Pathway/WP3655_r142023/Complex/b236e> .

obo:NCBITaxon_9606  obo:NCIT_C179773  "9606" .

<http://rdf.wikipathways.org/Pathway/WP3655_r142023/WP/Interaction/id6b85dc31>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP3655_r142023> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP3655_r142023/Interaction/id6b85dc31> ;
        wp:participants   <https://identifiers.org/hgnc.symbol/IRF6> , <https://identifiers.org/hgnc.symbol/TFAP2A> ;
        wp:source         <https://identifiers.org/hgnc.symbol/TFAP2A> ;
        wp:target         <https://identifiers.org/hgnc.symbol/IRF6> .

<http://rdf.wikipathways.org/Pathway/WP3655_r142023/WP/Interaction/id8c81ce6b>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP3655_r142023> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP3655_r142023/Interaction/id8c81ce6b> ;
        wp:participants   <https://identifiers.org/hgnc.symbol/IRF6> , <https://identifiers.org/hgnc.symbol/TP63> ;
        wp:source         <https://identifiers.org/hgnc.symbol/TP63> ;
        wp:target         <https://identifiers.org/hgnc.symbol/IRF6> .
