@prefix biopax:  <http://www.biopax.org/release/biopax-level3.owl#> .
@prefix cito:    <http://purl.org/spar/cito/> .
@prefix dc:      <http://purl.org/dc/elements/1.1/> .
@prefix dcterms: <http://purl.org/dc/terms/> .
@prefix foaf:    <http://xmlns.com/foaf/0.1/> .
@prefix freq:    <http://purl.org/cld/freq/> .
@prefix gpml:    <http://vocabularies.wikipathways.org/gpml#> .
@prefix obo:     <http://purl.obolibrary.org/obo/> .
@prefix owl:     <http://www.w3.org/2002/07/owl#> .
@prefix pav:     <http://purl.org/pav/> .
@prefix prov:    <http://www.w3.org/ns/prov#> .
@prefix rdf:     <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix rdfs:    <http://www.w3.org/2000/01/rdf-schema#> .
@prefix skos:    <http://www.w3.org/2004/02/skos/core#> .
@prefix void:    <http://rdfs.org/ns/void#> .
@prefix wp:      <http://vocabularies.wikipathways.org/wp#> .
@prefix wprdf:   <http://rdf.wikipathways.org/> .
@prefix xsd:     <http://www.w3.org/2001/XMLSchema#> .

<https://identifiers.org/wikipathways/WP3962>
        pav:hasVersion  <https://identifiers.org/wikipathways/WP3962_r135410> .

<http://rdf.wikipathways.org/Pathway/WP3962_r135410/WP/Interaction/acbb8>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP3962_r135410> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP3962_r135410/Interaction/acbb8> ;
        wp:participants   <https://identifiers.org/chebi/CHEBI:23378> , <https://identifiers.org/ensembl/WBGene00000834> ;
        wp:source         <https://identifiers.org/ensembl/WBGene00000834> ;
        wp:target         <https://identifiers.org/chebi/CHEBI:23378> .

<http://rdf.wikipathways.org/Pathway/WP3962_r135410/WP/Interaction/id55938d53>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP3962_r135410> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP3962_r135410/Interaction/id55938d53> ;
        wp:participants   <https://identifiers.org/chebi/CHEBI:23378> , <https://identifiers.org/ensembl/WBGene00000834> ;
        wp:source         <https://identifiers.org/ensembl/WBGene00000834> ;
        wp:target         <https://identifiers.org/chebi/CHEBI:23378> .

<https://identifiers.org/ensembl/WBGene00000835>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "CUC-1" ;
        dc:identifier       <https://identifiers.org/ensembl/WBGene00000835> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "WBGene00000835" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP3962_r135410> , <http://rdf.wikipathways.org/Pathway/WP3962_r135410/WP/Interaction/id162bad2b> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/WBGene00000835> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/176102> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/G5EE41> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q29670625> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP3962_r135410/DataNode/f16ba> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/G5EE41> ;
        foaf:page           <https://www.ensembl.org/id/WBGene00000835> .

<https://identifiers.org/pubmed/27881675>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "27881675" ;
        dcterms:isPartOf    <https://identifiers.org/ensembl/WBGene00000834> , <https://identifiers.org/wikipathways/WP3962_r135410> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/27881675> .

<http://rdf.wikipathways.org/Pathway/WP3962_r135410/WP/Interaction/idd445f655>
        rdf:type          wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP3962_r135410> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP3962_r135410/Interaction/idd445f655> .

<http://rdf.wikipathways.org/Pathway/WP3962_r135410/WP/Interaction/f8892>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP3962_r135410> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP3962_r135410/Interaction/f8892> ;
        wp:participants   <https://identifiers.org/chebi/CHEBI:23378> , <https://identifiers.org/ensembl/WBGene00000834> ;
        wp:source         <https://identifiers.org/ensembl/WBGene00000834> ;
        wp:target         <https://identifiers.org/chebi/CHEBI:23378> .

obo:NCBITaxon_6239  obo:NCIT_C179773  "6239" .

<https://identifiers.org/chebi/CHEBI:23378>
        rdf:type            wp:DataNode , wp:Metabolite ;
        rdfs:label          "Cu" , "elemental copper" ;
        dc:identifier       <https://identifiers.org/chebi/CHEBI:23378> ;
        dc:source           "ChEBI" ;
        dcterms:identifier  "CHEBI:23378" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP3962_r135410/WP/Interaction/f8892> , <http://rdf.wikipathways.org/Pathway/WP3962_r135410/WP/Interaction/dcfa5> , <http://rdf.wikipathways.org/Pathway/WP3962_r135410/WP/Interaction/id55938d53> , <http://rdf.wikipathways.org/Pathway/WP3962_r135410/WP/Interaction/acbb8> , <https://identifiers.org/wikipathways/WP3962_r135410> , <http://rdf.wikipathways.org/Pathway/WP3962_r135410/WP/Interaction/f6272> , <http://rdf.wikipathways.org/Pathway/WP3962_r135410/WP/Interaction/id162bad2b> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:23378> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q71275796> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP3962_r135410/DataNode/ff5d7> , <http://rdf.wikipathways.org/Pathway/WP3962_r135410/DataNode/de144> , <http://rdf.wikipathways.org/Pathway/WP3962_r135410/DataNode/b279a> , <http://rdf.wikipathways.org/Pathway/WP3962_r135410/DataNode/e9a16> , <http://rdf.wikipathways.org/Pathway/WP3962_r135410/DataNode/bc2cd> , <http://rdf.wikipathways.org/Pathway/WP3962_r135410/DataNode/f9c0c> , <http://rdf.wikipathways.org/Pathway/WP3962_r135410/DataNode/cf863> , <http://rdf.wikipathways.org/Pathway/WP3962_r135410/DataNode/e2d88> , <http://rdf.wikipathways.org/Pathway/WP3962_r135410/DataNode/fae63> , <http://rdf.wikipathways.org/Pathway/WP3962_r135410/DataNode/e8ea2> , <http://rdf.wikipathways.org/Pathway/WP3962_r135410/DataNode/f0b3a> ;
        foaf:page           <https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:23378> .

<https://identifiers.org/wikipathways/WP3962_r135410>
        rdf:type                wp:Pathway , skos:Collection ;
        dc:identifier           <https://identifiers.org/wikipathways/WP3962> ;
        dc:source               "WikiPathways" ;
        dc:title                "Copper homeostasis"@en ;
        dcterms:description     "Adapted from figure 7 from Chun et al (see Bibliography). Cu homeostasis in worms is maintained by distinctly localized intestinal CUA-1 isoforms.\nA model of Cu homeostasis in C. elegans is shown. Dietary Cu ions are transported from the lumen of the intestine to the enterocytes by an unidentified Cu importer, and CUC-1 delivers Cu to CUA-1. Under basal Cu or Cu-deficient conditions, CUA-1.1 isoform localizes to the basolateral membrane and Golgi to either export Cu ions to peripheral tissues, or to direct Cu into the secretory pathway. CUA-1.2 consistently localizes to the basolateral membrane of enterocytes regardless of Cu conditions. CUA-1.1 is redistributed to the gut-granule membranes in response to elevated Cu levels in order to promote Cu detoxification in C. elegans.\"" ;
        dcterms:identifier      "WP3962" ;
        dcterms:references      <https://identifiers.org/pubmed/27881675> ;
        cito:cites              <https://identifiers.org/pubmed/27881675> ;
        wp:cellTypeOntologyTag  obo:CL_0002563 ;
        wp:isAbout              <http://rdf.wikipathways.org/Pathway/WP3962_r135410> ;
        wp:ontologyTag          wp:Curation:WormBase_Approved , obo:PW_0001002 , wp:Curation:AnalysisCollection , obo:CL_0002563 ;
        wp:organism             obo:NCBITaxon_6239 ;
        wp:organismName         "Caenorhabditis elegans" ;
        wp:pathwayOntologyTag   obo:PW_0001002 ;
        foaf:img                <https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=svg&pwTitle=Pathway:WP3962&oldid=135410> , <https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=png&pwTitle=Pathway:WP3962&oldid=135410> ;
        foaf:page               <http://www.wikipathways.org/instance/WP3962_r135410> .

<https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=png&pwTitle=Pathway:WP3962&oldid=135410>
        rdf:type        foaf:Image ;
        dcterms:format  "image/png" .

<https://identifiers.org/ensembl/WBGene00000834>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "CUA-1.1" , "CUA-1.2" ;
        dc:identifier       <https://identifiers.org/ensembl/WBGene00000834> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "WBGene00000834" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP3962_r135410/WP/Interaction/acbb8> , <http://rdf.wikipathways.org/Pathway/WP3962_r135410/WP/Interaction/f8892> , <http://rdf.wikipathways.org/Pathway/WP3962_r135410/WP/Interaction/id55938d53> , <https://identifiers.org/wikipathways/WP3962_r135410> , <http://rdf.wikipathways.org/Pathway/WP3962_r135410/WP/Interaction/dcfa5> ;
        dcterms:references  <https://identifiers.org/pubmed/27881675> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/WBGene00000834> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/176770> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/G5EE14> , <https://identifiers.org/uniprot/G5ED40> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q29686324> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP3962_r135410/DataNode/cb747> , <http://rdf.wikipathways.org/Pathway/WP3962_r135410/DataNode/caac2> , <http://rdf.wikipathways.org/Pathway/WP3962_r135410/DataNode/b5977> , <http://rdf.wikipathways.org/Pathway/WP3962_r135410/DataNode/ee286> , <http://rdf.wikipathways.org/Pathway/WP3962_r135410/DataNode/f3cb8> , <http://rdf.wikipathways.org/Pathway/WP3962_r135410/DataNode/aa2e7> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/G5EE14> , <http://purl.uniprot.org/uniprot/G5ED40> ;
        foaf:page           <https://www.ensembl.org/id/WBGene00000834> .

<http://rdf.wikipathways.org/Pathway/WP3962_r135410/WP/Interaction/f6272>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP3962_r135410> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP3962_r135410/Interaction/f6272> ;
        wp:participants   <https://identifiers.org/chebi/CHEBI:23378> ;
        wp:source         <https://identifiers.org/chebi/CHEBI:23378> ;
        wp:target         <https://identifiers.org/chebi/CHEBI:23378> .

<http://rdf.wikipathways.org/Pathway/WP3962_r135410/WP/Interaction/id162bad2b>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP3962_r135410> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP3962_r135410/Interaction/id162bad2b> ;
        wp:participants   <https://identifiers.org/ensembl/WBGene00000835> , <https://identifiers.org/chebi/CHEBI:23378> ;
        wp:source         <https://identifiers.org/chebi/CHEBI:23378> ;
        wp:target         <https://identifiers.org/ensembl/WBGene00000835> .

<http://rdf.wikipathways.org/Pathway/WP3962_r135410/WP/Interaction/dcfa5>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP3962_r135410> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP3962_r135410/Interaction/dcfa5> ;
        wp:participants   <https://identifiers.org/chebi/CHEBI:23378> , <https://identifiers.org/ensembl/WBGene00000834> ;
        wp:source         <https://identifiers.org/ensembl/WBGene00000834> ;
        wp:target         <https://identifiers.org/chebi/CHEBI:23378> .

<http://rdf.wikipathways.org/Pathway/WP3962_r135410/WP/Interaction/id495f922e>
        rdf:type          wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP3962_r135410> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP3962_r135410/Interaction/id495f922e> .

<https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=svg&pwTitle=Pathway:WP3962&oldid=135410>
        rdf:type        foaf:Image ;
        dcterms:format  "image/svg+xml" .
