@prefix biopax:  <http://www.biopax.org/release/biopax-level3.owl#> .
@prefix cito:    <http://purl.org/spar/cito/> .
@prefix dc:      <http://purl.org/dc/elements/1.1/> .
@prefix dcterms: <http://purl.org/dc/terms/> .
@prefix foaf:    <http://xmlns.com/foaf/0.1/> .
@prefix freq:    <http://purl.org/cld/freq/> .
@prefix gpml:    <http://vocabularies.wikipathways.org/gpml#> .
@prefix obo:     <http://purl.obolibrary.org/obo/> .
@prefix owl:     <http://www.w3.org/2002/07/owl#> .
@prefix pav:     <http://purl.org/pav/> .
@prefix prov:    <http://www.w3.org/ns/prov#> .
@prefix rdf:     <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix rdfs:    <http://www.w3.org/2000/01/rdf-schema#> .
@prefix skos:    <http://www.w3.org/2004/02/skos/core#> .
@prefix void:    <http://rdfs.org/ns/void#> .
@prefix wp:      <http://vocabularies.wikipathways.org/wp#> .
@prefix wprdf:   <http://rdf.wikipathways.org/> .
@prefix xsd:     <http://www.w3.org/2001/XMLSchema#> .

<https://identifiers.org/ncbigene/4842>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "NOS1" ;
        dc:identifier       <https://identifiers.org/ncbigene/4842> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "4842" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2447_r139972/WP/Interaction/id1e1bab7c> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/WP/Interaction/id69896d2b> , <https://identifiers.org/wikipathways/WP2447_r139972> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000089250> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/4842> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/NOS1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/P29475> , <https://identifiers.org/uniprot/B3VK56> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/aeb39> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/B3VK56> , <http://purl.uniprot.org/uniprot/P29475> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/4842> .

<https://identifiers.org/wikipathways/WP2267>
        rdf:type            wp:Pathway , wp:DataNode ;
        rdfs:label          "Synaptic transmission, glutamatergic" ;
        dc:identifier       <https://identifiers.org/wikipathways/WP2267> ;
        dc:source           "WikiPathways" ;
        dcterms:identifier  "WP2267" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2447_r139972> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/b5cbd> ;
        foaf:page           <https://www.wikipathways.org/instance/WP2267> .

<https://identifiers.org/uniprot/P01034>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "CYTC" ;
        dc:identifier       <https://identifiers.org/uniprot/P01034> ;
        dc:source           "UniProtKB" ;
        dcterms:identifier  "P01034" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/WP/Interaction/ida90aa669> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000101439> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/1471> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/CST3> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/P01034> , <https://identifiers.org/uniprot/A0A0K0K1J1> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/b06fe> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A0K0K1J1> , <http://purl.uniprot.org/uniprot/P01034> ;
        foaf:page           <http://www.uniprot.org/uniprot/P01034> .

<https://identifiers.org/ncbigene/834>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "CASP1" ;
        dc:identifier       <https://identifiers.org/ncbigene/834> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "834" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2447_r139972/WP/Interaction/idf5c9eb78> , <https://identifiers.org/wikipathways/WP2447_r139972> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000137752> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/834> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/CASP1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A8Q3SI67> , <https://identifiers.org/uniprot/G3V169> , <https://identifiers.org/uniprot/H0YEC7> , <https://identifiers.org/uniprot/A0A8Q3SIY2> , <https://identifiers.org/uniprot/B4DVD8> , <https://identifiers.org/uniprot/Q5FBZ0> , <https://identifiers.org/uniprot/B4DKN4> , <https://identifiers.org/uniprot/A0A8Q3SI00> , <https://identifiers.org/uniprot/P29466> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/e82f7> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q5FBZ0> , <http://purl.uniprot.org/uniprot/A0A8Q3SI67> , <http://purl.uniprot.org/uniprot/G3V169> , <http://purl.uniprot.org/uniprot/A0A8Q3SIY2> , <http://purl.uniprot.org/uniprot/P29466> , <http://purl.uniprot.org/uniprot/A0A8Q3SI00> , <http://purl.uniprot.org/uniprot/B4DKN4> , <http://purl.uniprot.org/uniprot/H0YEC7> , <http://purl.uniprot.org/uniprot/B4DVD8> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/834> .

<https://identifiers.org/ncbigene/847>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "CAT" ;
        dc:identifier       <https://identifiers.org/ncbigene/847> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "847" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2447_r139972> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000121691> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/847> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/CAT> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A3B3ITJ0> , <https://identifiers.org/uniprot/A0A384P5Q0> , <https://identifiers.org/uniprot/P04040> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/dae76> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P04040> , <http://purl.uniprot.org/uniprot/A0A3B3ITJ0> , <http://purl.uniprot.org/uniprot/A0A384P5Q0> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/847> .

<https://identifiers.org/ncbigene/596>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "BCL2" ;
        dc:identifier       <https://identifiers.org/ncbigene/596> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "596" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2447_r139972> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000171791> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/596> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/BCL2> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A7I2V5Q7> , <https://identifiers.org/uniprot/A0A7I2V4W1> , <https://identifiers.org/uniprot/P10415> , <https://identifiers.org/uniprot/A0A024R2C4> , <https://identifiers.org/uniprot/A0A7I2V5Q9> , <https://identifiers.org/uniprot/A0A024R2B3> , <https://identifiers.org/uniprot/A0A7I2V3S7> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/d6fe8> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A7I2V3S7> , <http://purl.uniprot.org/uniprot/A0A7I2V5Q9> , <http://purl.uniprot.org/uniprot/A0A024R2C4> , <http://purl.uniprot.org/uniprot/A0A7I2V4W1> , <http://purl.uniprot.org/uniprot/A0A7I2V5Q7> , <http://purl.uniprot.org/uniprot/A0A024R2B3> , <http://purl.uniprot.org/uniprot/P10415> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/596> .

<https://identifiers.org/ncbigene/1616>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "DAXX" ;
        dc:identifier       <https://identifiers.org/ncbigene/1616> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "1616" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2447_r139972/WP/Interaction/id142719ee> , <https://identifiers.org/wikipathways/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/WP/Interaction/id94a8676c> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000204209> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/113523636> , <https://identifiers.org/ncbigene/1616> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/DAXX> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q9UER7> , <https://identifiers.org/uniprot/A0A994J7Y1> , <https://identifiers.org/uniprot/A2AB94> , <https://identifiers.org/uniprot/B4E1C1> , <https://identifiers.org/uniprot/Q4VX54> , <https://identifiers.org/uniprot/A0A024RCS3> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/f6282> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q9UER7> , <http://purl.uniprot.org/uniprot/A0A994J7Y1> , <http://purl.uniprot.org/uniprot/A2AB94> , <http://purl.uniprot.org/uniprot/A0A024RCS3> , <http://purl.uniprot.org/uniprot/B4E1C1> , <http://purl.uniprot.org/uniprot/Q4VX54> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/1616> .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/WP/Interaction/id9999669c>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2447_r139972> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id9999669c> ;
        wp:participants   <https://identifiers.org/ncbigene/836> , <https://identifiers.org/ncbigene/842> ;
        wp:source         <https://identifiers.org/ncbigene/842> ;
        wp:target         <https://identifiers.org/ncbigene/836> .

<https://identifiers.org/hmdb/HMDB0001039>
        rdf:type            wp:DataNode , wp:Metabolite ;
        rdfs:label          "OH" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/XLYOFNOQVPJJNP-UHFFFAOYSA-N> ;
        dc:identifier       <https://identifiers.org/hmdb/HMDB0001039> ;
        dc:source           "HMDB" ;
        dcterms:identifier  "HMDB0001039" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2447_r139972/WP/Interaction/id117c419f> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/WP/Interaction/id6a75a338> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/WP/Interaction/a5b33> , <https://identifiers.org/wikipathways/WP2447_r139972> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:16234> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/936> ;
        wp:bdbHmdb          <https://identifiers.org/hmdb/HMDB0001039> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/XLYOFNOQVPJJNP-UHFFFAOYSA-M> ;
        wp:bdbKeggCompound  <https://identifiers.org/kegg.compound/C01328> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID961> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q199877> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/e92a9> ;
        foaf:page           <http://www.hmdb.ca/metabolites/HMDB0001039> .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/WP/Interaction/id117c419f>
        rdf:type          wp:Interaction , wp:DirectedInteraction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2447_r139972> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idfbf571ae> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id117c419f> ;
        wp:participants   <https://identifiers.org/hmdb/HMDB0001039> , <https://identifiers.org/ncbigene/6647> , <https://identifiers.org/hmdb/HMDB0003125> ;
        wp:source         <https://identifiers.org/ncbigene/6647> , <https://identifiers.org/hmdb/HMDB0003125> ;
        wp:target         <https://identifiers.org/hmdb/HMDB0001039> .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/WP/Interaction/id719c925>
        rdf:type          wp:Inhibition , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2447_r139972> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id719c925> ;
        wp:participants   <https://identifiers.org/uniprot/P43004> , <https://identifiers.org/chebi/CHEBI:26523> ;
        wp:source         <https://identifiers.org/chebi/CHEBI:26523> ;
        wp:target         <https://identifiers.org/uniprot/P43004> .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/WP/Interaction/id6fcdb47>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2447_r139972> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id6fcdb47> ;
        wp:participants   <https://identifiers.org/hmdb/HMDB0003378> ;
        wp:source         <https://identifiers.org/hmdb/HMDB0003378> ;
        wp:target         <https://identifiers.org/hmdb/HMDB0003378> .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Complex/b3274>
        rdf:type          wp:Complex , wp:DataNode ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2447_r139972> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Group/b3274> ;
        wp:participants   <https://identifiers.org/ncbigene/5605> , <https://identifiers.org/ncbigene/5608> .

<https://identifiers.org/ncbigene/79139>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "Derlin-1" ;
        dc:identifier       <https://identifiers.org/ncbigene/79139> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "79139" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2447_r139972/WP/Interaction/id751c8da1> , <https://identifiers.org/wikipathways/WP2447_r139972> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000136986> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/79139> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/DERL1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q9BUN8> , <https://identifiers.org/uniprot/B4E1G1> , <https://identifiers.org/uniprot/A0A024R9G3> , <https://identifiers.org/uniprot/E5RGY0> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/a1e19> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A024R9G3> , <http://purl.uniprot.org/uniprot/B4E1G1> , <http://purl.uniprot.org/uniprot/Q9BUN8> , <http://purl.uniprot.org/uniprot/E5RGY0> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/79139> .

<https://identifiers.org/hmdb/HMDB0003378>
        rdf:type            wp:DataNode , wp:Metabolite ;
        rdfs:label          "NO" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/MWUXSHHQAYIFBG-UHFFFAOYSA-N> ;
        dc:identifier       <https://identifiers.org/hmdb/HMDB0003378> ;
        dc:source           "HMDB" ;
        dcterms:identifier  "HMDB0003378" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2447_r139972/WP/Interaction/id6fcdb47> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/WP/Interaction/id8c85cf83> , <https://identifiers.org/wikipathways/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/WP/Interaction/id85aed399> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/WP/Interaction/id2dedab80> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/WP/Interaction/idb3584e45> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/WP/Interaction/id7d4f73cd> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:16480> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/127983> ;
        wp:bdbHmdb          <https://identifiers.org/hmdb/HMDB0003378> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/MWUXSHHQAYIFBG-UHFFFAOYSA-N> ;
        wp:bdbKeggCompound  <https://identifiers.org/kegg.compound/C00533> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID145068> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q207843> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/bd217> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/e8673> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/e9f96> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/bafb8> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/bb36d> ;
        foaf:page           <http://www.hmdb.ca/metabolites/HMDB0003378> .

<https://identifiers.org/uniprot/O96008>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "TOM40" ;
        dc:identifier       <https://identifiers.org/uniprot/O96008> ;
        dc:source           "UniProtKB" ;
        dcterms:identifier  "O96008" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2447_r139972> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000130204> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/10452> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/TOMM40> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/O96008> , <https://identifiers.org/uniprot/K7EKG6> , <https://identifiers.org/uniprot/K7EKG4> , <https://identifiers.org/uniprot/K7EJ57> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/bdd14> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/K7EKG6> , <http://purl.uniprot.org/uniprot/K7EKG4> , <http://purl.uniprot.org/uniprot/K7EJ57> , <http://purl.uniprot.org/uniprot/O96008> ;
        foaf:page           <http://www.uniprot.org/uniprot/O96008> .

<https://identifiers.org/hmdb/HMDB0002179>
        rdf:type            wp:Metabolite , wp:DataNode ;
        rdfs:label          "ONOO-" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/CMFNMSMUKZHDEY-UHFFFAOYSA-N> ;
        dc:identifier       <https://identifiers.org/hmdb/HMDB0002179> ;
        dc:source           "HMDB" ;
        dcterms:identifier  "HMDB0002179" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2447_r139972/WP/Interaction/id4993787b> , <https://identifiers.org/wikipathways/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/WP/Interaction/id7d4f73cd> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/WP/Interaction/id6fc14d0a> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:25942> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/109951> ;
        wp:bdbHmdb          <https://identifiers.org/hmdb/HMDB0002179> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/CMFNMSMUKZHDEY-UHFFFAOYSA-N> ;
        wp:bdbKeggCompound  <https://identifiers.org/kegg.compound/C16845> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID123349> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q7169514> , <http://www.wikidata.org/entity/Q419130> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/e0fcd> ;
        foaf:page           <http://www.hmdb.ca/metabolites/HMDB0002179> .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/WP/Interaction/id8197ddde>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2447_r139972> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id8197ddde> ;
        wp:participants   <https://identifiers.org/chebi/CHEBI:26523> , <https://identifiers.org/ncbigene/6647> ;
        wp:source         <https://identifiers.org/ncbigene/6647> ;
        wp:target         <https://identifiers.org/chebi/CHEBI:26523> .

<https://identifiers.org/ncbigene/9973>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "CCS" ;
        dc:identifier       <https://identifiers.org/ncbigene/9973> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "9973" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/WP/Interaction/idd37d0e73> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000173992> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/9973> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/CCS> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/E9PK03> , <https://identifiers.org/uniprot/O14618> , <https://identifiers.org/uniprot/J3KNF4> , <https://identifiers.org/uniprot/E9PP76> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/ef623> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/O14618> , <http://purl.uniprot.org/uniprot/E9PP76> , <http://purl.uniprot.org/uniprot/E9PK03> , <http://purl.uniprot.org/uniprot/J3KNF4> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/9973> .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/WP/Interaction/idde65c6be>
        rdf:type          wp:Interaction , wp:DirectedInteraction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2447_r139972> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idde65c6be> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id2949d535> ;
        wp:participants   <https://identifiers.org/uniprot/P43004> , <https://identifiers.org/hmdb/HMDB0000148> ;
        wp:source         <https://identifiers.org/uniprot/P43004> , <https://identifiers.org/hmdb/HMDB0000148> ;
        wp:target         <https://identifiers.org/hmdb/HMDB0000148> .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/WP/Interaction/id5d12dff3>
        rdf:type          wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2447_r139972> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id5d12dff3> ;
        wp:participants   <https://identifiers.org/ncbigene/5879> , <https://identifiers.org/ncbigene/57679> .

<https://identifiers.org/wikipathways/WP707>
        rdf:type            wp:Pathway , wp:DataNode ;
        rdfs:label          "p53 signaling pathway" ;
        dc:identifier       <https://identifiers.org/wikipathways/WP707> ;
        dc:source           "WikiPathways" ;
        dcterms:identifier  "WP707" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2447_r139972> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/a67f7> ;
        foaf:page           <https://www.wikipathways.org/instance/WP707> .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/WP/Interaction/id69896d2b>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2447_r139972> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id69896d2b> ;
        wp:participants   <https://identifiers.org/ncbigene/4842> , <https://identifiers.org/hmdb/HMDB0000464> ;
        wp:source         <https://identifiers.org/hmdb/HMDB0000464> ;
        wp:target         <https://identifiers.org/ncbigene/4842> .

<https://identifiers.org/ncbigene/4747>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "NEFL" ;
        dc:identifier       <https://identifiers.org/ncbigene/4747> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "4747" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2447_r139972/WP/Interaction/idb3aea929> , <https://identifiers.org/wikipathways/WP2447_r139972> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000277586> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/4747> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/NEFL> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/P07196> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/fcde2> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P07196> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/4747> .

<https://identifiers.org/ncbigene/2876>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "GPX1" ;
        dc:identifier       <https://identifiers.org/ncbigene/2876> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "2876" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/WP/Interaction/idd6d367a2> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000233276> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/2876> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/GPX1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A994J702> , <https://identifiers.org/uniprot/A0A2R8Y6B6> , <https://identifiers.org/uniprot/A0A994J4E2> , <https://identifiers.org/uniprot/Q7L4Q3> , <https://identifiers.org/uniprot/A0A7I2YMD7> , <https://identifiers.org/uniprot/A0A994J430> , <https://identifiers.org/uniprot/P07203> , <https://identifiers.org/uniprot/A0A994J7E8> , <https://identifiers.org/uniprot/A0A994J4K6> , <https://identifiers.org/uniprot/A0A7I2UQ36> , <https://identifiers.org/uniprot/A0A994J707> , <https://identifiers.org/uniprot/A0A994J4L4> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/f4cf0> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P07203> , <http://purl.uniprot.org/uniprot/A0A2R8Y6B6> , <http://purl.uniprot.org/uniprot/A0A994J4L4> , <http://purl.uniprot.org/uniprot/A0A994J7E8> , <http://purl.uniprot.org/uniprot/A0A994J707> , <http://purl.uniprot.org/uniprot/A0A994J702> , <http://purl.uniprot.org/uniprot/A0A7I2UQ36> , <http://purl.uniprot.org/uniprot/A0A994J4E2> , <http://purl.uniprot.org/uniprot/Q7L4Q3> , <http://purl.uniprot.org/uniprot/A0A994J430> , <http://purl.uniprot.org/uniprot/A0A7I2YMD7> , <http://purl.uniprot.org/uniprot/A0A994J4K6> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/2876> .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/WP/Interaction/id7c9c96e3>
        rdf:type          wp:Interaction , wp:DirectedInteraction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2447_r139972> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id7c9c96e3> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idbf7b8b9> ;
        wp:participants   <https://identifiers.org/ncbigene/6647> , <https://identifiers.org/hmdb/HMDB0003125> , <https://identifiers.org/hmdb/HMDB0002168> ;
        wp:source         <https://identifiers.org/ncbigene/6647> , <https://identifiers.org/hmdb/HMDB0002168> ;
        wp:target         <https://identifiers.org/hmdb/HMDB0003125> .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/WP/Interaction/id2dedab80>
        rdf:type          wp:Conversion , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2447_r139972> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id2dedab80> ;
        wp:participants   <https://identifiers.org/hmdb/HMDB0003378> , <https://identifiers.org/hmdb/HMDB0000517> ;
        wp:source         <https://identifiers.org/hmdb/HMDB0000517> ;
        wp:target         <https://identifiers.org/hmdb/HMDB0003378> .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/Complex/d820d>
        rdf:type          wp:Complex , wp:DataNode ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2447_r139972> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Group/d820d> ;
        wp:participants   <https://identifiers.org/ncbigene/5533> , <https://identifiers.org/ncbigene/5530> , <https://identifiers.org/ncbigene/5532> .

<https://identifiers.org/uniprot/P43004>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "EAAT2" ;
        dc:identifier       <https://identifiers.org/uniprot/P43004> ;
        dc:source           "UniProtKB" ;
        dcterms:identifier  "P43004" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2447_r139972/WP/Interaction/idde65c6be> , <https://identifiers.org/wikipathways/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/WP/Interaction/id719c925> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000110436> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/6506> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/SLC1A2> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A2R8YG01> , <https://identifiers.org/uniprot/A0A2U3U0E3> , <https://identifiers.org/uniprot/A0A2R8YH93> , <https://identifiers.org/uniprot/A0A2R8Y862> , <https://identifiers.org/uniprot/A0A2R8Y642> , <https://identifiers.org/uniprot/A0A2R8Y4N0> , <https://identifiers.org/uniprot/A0A2R8Y4W1> , <https://identifiers.org/uniprot/A0A2U3TZS7> , <https://identifiers.org/uniprot/C9J9N5> , <https://identifiers.org/uniprot/H0YEK4> , <https://identifiers.org/uniprot/A0A2R8Y6J5> , <https://identifiers.org/uniprot/A0A2R8Y4D1> , <https://identifiers.org/uniprot/A0A2R8Y860> , <https://identifiers.org/uniprot/P43004> , <https://identifiers.org/uniprot/H0YEB1> , <https://identifiers.org/uniprot/A0A2R8YCL7> , <https://identifiers.org/uniprot/A0A2R8Y6B8> , <https://identifiers.org/uniprot/A0A2R8Y5Y1> , <https://identifiers.org/uniprot/A0A163QEF0> , <https://identifiers.org/uniprot/A0A2R8YHI4> , <https://identifiers.org/uniprot/A0A2R8YFE3> , <https://identifiers.org/uniprot/A0A2R8Y740> , <https://identifiers.org/uniprot/A2A2U1> , <https://identifiers.org/uniprot/A0A2R8YD46> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/c93d3> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A2R8YG01> , <http://purl.uniprot.org/uniprot/A2A2U1> , <http://purl.uniprot.org/uniprot/A0A163QEF0> , <http://purl.uniprot.org/uniprot/C9J9N5> , <http://purl.uniprot.org/uniprot/A0A2R8YCL7> , <http://purl.uniprot.org/uniprot/A0A2R8Y862> , <http://purl.uniprot.org/uniprot/A0A2R8Y740> , <http://purl.uniprot.org/uniprot/A0A2U3TZS7> , <http://purl.uniprot.org/uniprot/A0A2R8Y4N0> , <http://purl.uniprot.org/uniprot/A0A2R8YHI4> , <http://purl.uniprot.org/uniprot/A0A2R8Y5Y1> , <http://purl.uniprot.org/uniprot/A0A2R8Y860> , <http://purl.uniprot.org/uniprot/A0A2R8YFE3> , <http://purl.uniprot.org/uniprot/A0A2R8YH93> , <http://purl.uniprot.org/uniprot/A0A2R8Y6J5> , <http://purl.uniprot.org/uniprot/H0YEB1> , <http://purl.uniprot.org/uniprot/A0A2R8Y642> , <http://purl.uniprot.org/uniprot/A0A2R8Y6B8> , <http://purl.uniprot.org/uniprot/A0A2R8Y4D1> , <http://purl.uniprot.org/uniprot/A0A2R8Y4W1> , <http://purl.uniprot.org/uniprot/P43004> , <http://purl.uniprot.org/uniprot/A0A2R8YD46> , <http://purl.uniprot.org/uniprot/A0A2U3U0E3> , <http://purl.uniprot.org/uniprot/H0YEK4> ;
        foaf:page           <http://www.uniprot.org/uniprot/P43004> .

<https://identifiers.org/ncbigene/4741>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "NEFM" ;
        dc:identifier       <https://identifiers.org/ncbigene/4741> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "4741" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2447_r139972/WP/Interaction/id4993787b> , <https://identifiers.org/wikipathways/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/WP/Interaction/id6a75a338> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000104722> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/4741> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/NEFM> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/E7EMV2> , <https://identifiers.org/uniprot/E7ESP9> , <https://identifiers.org/uniprot/P07197> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/d4a30> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P07197> , <http://purl.uniprot.org/uniprot/E7ESP9> , <http://purl.uniprot.org/uniprot/E7EMV2> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/4741> .

<https://identifiers.org/kegg.compound/C00076>
        rdf:type            wp:DataNode , wp:Metabolite ;
        rdfs:label          "Ca²⁺" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/OYPRJOBELJOOCE-UHFFFAOYSA-N> , <https://identifiers.org/inchikey/BHPQYMZQTOCNFJ-UHFFFAOYSA-N> ;
        dc:identifier       <https://identifiers.org/kegg.compound/C00076> ;
        dc:source           "KEGG Compound" ;
        dcterms:identifier  "C00076" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2447_r139972/WP/Interaction/idd46b0994> , <https://identifiers.org/wikipathways/WP2447_r139972> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:29320> , <https://identifiers.org/chebi/CHEBI:22984> , <https://identifiers.org/chebi/CHEBI:29108> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/266> , <https://identifiers.org/chemspider/4573905> ;
        wp:bdbHmdb          <https://identifiers.org/hmdb/HMDB0000464> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/OYPRJOBELJOOCE-UHFFFAOYSA-N> , <https://identifiers.org/inchikey/BHPQYMZQTOCNFJ-UHFFFAOYSA-N> ;
        wp:bdbKeggCompound  <https://identifiers.org/kegg.compound/C00076> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID5460341> , <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID271> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q706> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/aa8a3> ;
        foaf:page           <http://www.genome.jp/dbget-bin/www_bget?cpd:C00076> .

<https://identifiers.org/hmdb/HMDB0002111>
        rdf:type            wp:Metabolite , wp:DataNode ;
        rdfs:label          "H₂O" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/XLYOFNOQVPJJNP-UHFFFAOYSA-N> ;
        dc:identifier       <https://identifiers.org/hmdb/HMDB0002111> ;
        dc:source           "HMDB" ;
        dcterms:identifier  "HMDB0002111" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/WP/Interaction/id69b8a250> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:15377> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/937> ;
        wp:bdbHmdb          <https://identifiers.org/hmdb/HMDB0002111> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/XLYOFNOQVPJJNP-UHFFFAOYSA-N> ;
        wp:bdbKeggCompound  <https://identifiers.org/kegg.compound/C00001> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID962> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q283> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/d81a7> ;
        foaf:page           <http://www.hmdb.ca/metabolites/HMDB0002111> .

<https://identifiers.org/ncbigene/5605>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "MKK3" ;
        dc:identifier       <https://identifiers.org/ncbigene/5605> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "5605" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Complex/b3274> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000126934> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/5605> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/MAP2K2> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/M0R1B6> , <https://identifiers.org/uniprot/P36507> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/dea3c> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/M0R1B6> , <http://purl.uniprot.org/uniprot/P36507> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/5605> .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/WP/Interaction/id1de00d7a>
        rdf:type          wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2447_r139972> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idd75808de> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id1de00d7a> ;
        wp:participants   <https://identifiers.org/ncbigene/1432> , <https://identifiers.org/ncbigene/4217> .

<https://identifiers.org/hmdb/HMDB0000517>
        rdf:type            wp:Metabolite , wp:DataNode ;
        rdfs:label          "L-Arginine" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/ODKSFYDXXFIFQN-BYPYZUCNSA-N> ;
        dc:identifier       <https://identifiers.org/hmdb/HMDB0000517> ;
        dc:source           "HMDB" ;
        dcterms:identifier  "HMDB0000517" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2447_r139972/WP/Interaction/id2dedab80> , <https://identifiers.org/wikipathways/WP2447_r139972> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:16467> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/6082> ;
        wp:bdbHmdb          <https://identifiers.org/hmdb/HMDB0000517> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/ODKSFYDXXFIFQN-BYPYZUCNSA-N> ;
        wp:bdbKeggCompound  <https://identifiers.org/kegg.compound/C00062> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID6322> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q173670> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/f2d32> ;
        foaf:page           <http://www.hmdb.ca/metabolites/HMDB0000517> .

<https://identifiers.org/ncbigene/5533>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "PPP3CC" ;
        dc:identifier       <https://identifiers.org/ncbigene/5533> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "5533" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Complex/d820d> , <https://identifiers.org/wikipathways/WP2447_r139972> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000120910> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/5533> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/PPP3CC> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/H0YB04> , <https://identifiers.org/uniprot/H0YB02> , <https://identifiers.org/uniprot/E5RJH4> , <https://identifiers.org/uniprot/P48454> , <https://identifiers.org/uniprot/H0YC26> , <https://identifiers.org/uniprot/G3V111> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/ed0c3> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/H0YB04> , <http://purl.uniprot.org/uniprot/P48454> , <http://purl.uniprot.org/uniprot/H0YC26> , <http://purl.uniprot.org/uniprot/H0YB02> , <http://purl.uniprot.org/uniprot/G3V111> , <http://purl.uniprot.org/uniprot/E5RJH4> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/5533> .

<https://identifiers.org/ncbigene/5879>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "RAC1" ;
        dc:identifier       <https://identifiers.org/ncbigene/5879> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "5879" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2447_r139972/WP/Interaction/id5d12dff3> , <https://identifiers.org/wikipathways/WP2447_r139972> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000136238> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/5879> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/RAC1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A4D2P1> , <https://identifiers.org/uniprot/A0A994J4S4> , <https://identifiers.org/uniprot/A0A994J6T1> , <https://identifiers.org/uniprot/P63000> , <https://identifiers.org/uniprot/A4D2P0> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/e81dd> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A4D2P0> , <http://purl.uniprot.org/uniprot/A0A994J4S4> , <http://purl.uniprot.org/uniprot/P63000> , <http://purl.uniprot.org/uniprot/A0A994J6T1> , <http://purl.uniprot.org/uniprot/A4D2P1> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/5879> .

<https://doi.org/10.1016%2Fj.softx.2024.101701>
        rdf:type            wp:PublicationReference ;
        dc:source           "DOI" ;
        dcterms:identifier  "10.1016/j.softx.2024.101701" ;
        cito:cites          <https://identifiers.org/wikipathways/WP2447> .

<https://identifiers.org/ncbigene/2890>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "GRIA1" ;
        dc:identifier       <https://identifiers.org/ncbigene/2890> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "2890" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/WP/Interaction/ide9959d31> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000155511> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/2890> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/GRIA1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/P42261> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/f7616> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P42261> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/2890> .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/WP/Interaction/idf5c9eb78>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2447_r139972> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idf5c9eb78> ;
        wp:participants   <https://identifiers.org/ncbigene/637> , <https://identifiers.org/ncbigene/834> ;
        wp:source         <https://identifiers.org/ncbigene/834> ;
        wp:target         <https://identifiers.org/ncbigene/637> .

<https://identifiers.org/ncbigene/7132>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "TNFR" ;
        dc:identifier       <https://identifiers.org/ncbigene/7132> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "7132" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2447_r139972/WP/Interaction/id94a8676c> , <https://identifiers.org/wikipathways/WP2447_r139972> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000067182> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/7132> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/TNFRSF1A> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/F5H7N1> , <https://identifiers.org/uniprot/P19438> , <https://identifiers.org/uniprot/F5H8A6> , <https://identifiers.org/uniprot/A0A8V8TLL5> , <https://identifiers.org/uniprot/F5H061> , <https://identifiers.org/uniprot/F5H6Z2> , <https://identifiers.org/uniprot/F5H4T5> , <https://identifiers.org/uniprot/F5H6V7> , <https://identifiers.org/uniprot/F5GWJ4> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/c620a> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/F5H6Z2> , <http://purl.uniprot.org/uniprot/F5H7N1> , <http://purl.uniprot.org/uniprot/F5H4T5> , <http://purl.uniprot.org/uniprot/F5H6V7> , <http://purl.uniprot.org/uniprot/A0A8V8TLL5> , <http://purl.uniprot.org/uniprot/F5H061> , <http://purl.uniprot.org/uniprot/F5GWJ4> , <http://purl.uniprot.org/uniprot/P19438> , <http://purl.uniprot.org/uniprot/F5H8A6> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/7132> .

<https://identifiers.org/ncbigene/581>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "BAX" ;
        dc:identifier       <https://identifiers.org/ncbigene/581> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "581" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2447_r139972> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000087088> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/581> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/BAX> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/H0YA56> , <https://identifiers.org/uniprot/I6LPK7> , <https://identifiers.org/uniprot/Q07812> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/a0d6a> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/H0YA56> , <http://purl.uniprot.org/uniprot/I6LPK7> , <http://purl.uniprot.org/uniprot/Q07812> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/581> .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/WP/Interaction/id69b8a250>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2447_r139972> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id69b8a250> ;
        wp:participants   <https://identifiers.org/hmdb/HMDB0002111> , <https://identifiers.org/hmdb/HMDB0003125> ;
        wp:source         <https://identifiers.org/hmdb/HMDB0003125> ;
        wp:target         <https://identifiers.org/hmdb/HMDB0002111> .

<https://identifiers.org/hmdb/HMDB0000657>
        rdf:type            wp:Metabolite , wp:DataNode ;
        rdfs:label          "Cu" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/JPVYNHNXODAKFH-UHFFFAOYSA-N> ;
        dc:identifier       <https://identifiers.org/hmdb/HMDB0000657> ;
        dc:source           "HMDB" ;
        dcterms:identifier  "HMDB0000657" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/WP/Interaction/idd37d0e73> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:29036> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/25221> ;
        wp:bdbHmdb          <https://identifiers.org/hmdb/HMDB0000657> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/JPVYNHNXODAKFH-UHFFFAOYSA-N> ;
        wp:bdbKeggCompound  <https://identifiers.org/kegg.compound/C00070> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID27099> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q27094182> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/a6118> ;
        foaf:page           <http://www.hmdb.ca/metabolites/HMDB0000657> .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/WP/Interaction/bcc7f>
        rdf:type          wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2447_r139972> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/bcc7f> ;
        wp:participants   <https://identifiers.org/chebi/CHEBI:26523> , <https://identifiers.org/hmdb/HMDB0002168> .

obo:NCBITaxon_9606  obo:NCIT_C179773  "9606" .

<https://identifiers.org/ensembl/ENSG00000204403>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "CASP12" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000204403> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000204403" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2447_r139972> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000204403> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/100506742> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/CASP12> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q6UXS9> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18068044> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/e257e> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q6UXS9> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000204403> .

<https://identifiers.org/ncbigene/57679>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "ALS2" ;
        dc:identifier       <https://identifiers.org/ncbigene/57679> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "57679" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/WP/Interaction/id5d12dff3> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/WP/Interaction/id8d950ddc> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000003393> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/57679> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/ALS2> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A7P0T980> , <https://identifiers.org/uniprot/A0A0S2Z5I4> , <https://identifiers.org/uniprot/A0A7P0TAH8> , <https://identifiers.org/uniprot/A0A7P0T958> , <https://identifiers.org/uniprot/J3KQ43> , <https://identifiers.org/uniprot/Q96Q42> , <https://identifiers.org/uniprot/A0A7P0TAM1> , <https://identifiers.org/uniprot/A0A7P0T9P3> , <https://identifiers.org/uniprot/H0Y696> , <https://identifiers.org/uniprot/A0A7P0T9R1> , <https://identifiers.org/uniprot/A0A7P0T8F3> , <https://identifiers.org/uniprot/A0A7P0Z4M6> , <https://identifiers.org/uniprot/A0A7P0T8W6> , <https://identifiers.org/uniprot/A0A7P0T993> , <https://identifiers.org/uniprot/A0A7P0TBK0> , <https://identifiers.org/uniprot/A0A7P0Z4J9> , <https://identifiers.org/uniprot/A0A7P0T9U5> , <https://identifiers.org/uniprot/A0A7P0TAC4> , <https://identifiers.org/uniprot/A0A7P0T8R1> , <https://identifiers.org/uniprot/A0A7P0T813> , <https://identifiers.org/uniprot/A0A7P0Z4F3> , <https://identifiers.org/uniprot/A0A7P0T951> , <https://identifiers.org/uniprot/A0A0S2Z5Q7> , <https://identifiers.org/uniprot/A0A7P0T976> , <https://identifiers.org/uniprot/A0A7P0T8P3> , <https://identifiers.org/uniprot/A0A7P0T9K3> , <https://identifiers.org/uniprot/A0A7P0T8T2> , <https://identifiers.org/uniprot/A0A7P0TBB0> , <https://identifiers.org/uniprot/A0A7P0Z4I4> , <https://identifiers.org/uniprot/A0A7P0Z499> , <https://identifiers.org/uniprot/J3KQ33> , <https://identifiers.org/uniprot/A0A7P0T9V4> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/d1b7a> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A7P0T9R1> , <http://purl.uniprot.org/uniprot/A0A7P0T980> , <http://purl.uniprot.org/uniprot/A0A7P0T9U5> , <http://purl.uniprot.org/uniprot/A0A7P0Z499> , <http://purl.uniprot.org/uniprot/A0A7P0T958> , <http://purl.uniprot.org/uniprot/A0A7P0T8T2> , <http://purl.uniprot.org/uniprot/A0A7P0T9K3> , <http://purl.uniprot.org/uniprot/A0A7P0T993> , <http://purl.uniprot.org/uniprot/A0A7P0TAC4> , <http://purl.uniprot.org/uniprot/A0A7P0T8P3> , <http://purl.uniprot.org/uniprot/A0A7P0TAM1> , <http://purl.uniprot.org/uniprot/J3KQ43> , <http://purl.uniprot.org/uniprot/A0A7P0Z4J9> , <http://purl.uniprot.org/uniprot/H0Y696> , <http://purl.uniprot.org/uniprot/A0A0S2Z5I4> , <http://purl.uniprot.org/uniprot/A0A7P0T8R1> , <http://purl.uniprot.org/uniprot/A0A7P0T9V4> , <http://purl.uniprot.org/uniprot/A0A0S2Z5Q7> , <http://purl.uniprot.org/uniprot/A0A7P0TBK0> , <http://purl.uniprot.org/uniprot/A0A7P0T813> , <http://purl.uniprot.org/uniprot/A0A7P0T951> , <http://purl.uniprot.org/uniprot/J3KQ33> , <http://purl.uniprot.org/uniprot/A0A7P0TBB0> , <http://purl.uniprot.org/uniprot/Q96Q42> , <http://purl.uniprot.org/uniprot/A0A7P0T9P3> , <http://purl.uniprot.org/uniprot/A0A7P0T8F3> , <http://purl.uniprot.org/uniprot/A0A7P0Z4I4> , <http://purl.uniprot.org/uniprot/A0A7P0T976> , <http://purl.uniprot.org/uniprot/A0A7P0Z4M6> , <http://purl.uniprot.org/uniprot/A0A7P0Z4F3> , <http://purl.uniprot.org/uniprot/A0A7P0TAH8> , <http://purl.uniprot.org/uniprot/A0A7P0T8W6> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/57679> .

<https://identifiers.org/wikipathways/WP183>
        rdf:type            wp:Pathway , wp:DataNode ;
        rdfs:label          "Proteasome" ;
        dc:identifier       <https://identifiers.org/wikipathways/WP183> ;
        dc:source           "WikiPathways" ;
        dcterms:identifier  "WP183" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2447_r139972> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/b69ab> ;
        foaf:page           <https://www.wikipathways.org/instance/WP183> .

<https://identifiers.org/ncbigene/5532>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "PPP3CB" ;
        dc:identifier       <https://identifiers.org/ncbigene/5532> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "5532" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Complex/d820d> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000107758> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/5532> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/PPP3CB> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q5F2F8> , <https://identifiers.org/uniprot/P16298> , <https://identifiers.org/uniprot/Q5F2G0> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/b0f78> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q5F2G0> , <http://purl.uniprot.org/uniprot/P16298> , <http://purl.uniprot.org/uniprot/Q5F2F8> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/5532> .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/WP/Interaction/id136847e9>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2447_r139972> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id136847e9> ;
        wp:participants   <https://identifiers.org/ncbigene/842> , <https://identifiers.org/ncbigene/317> ;
        wp:source         <https://identifiers.org/ncbigene/317> ;
        wp:target         <https://identifiers.org/ncbigene/842> .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/WP/Interaction/idd46b0994>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2447_r139972> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idd46b0994> ;
        wp:participants   <https://identifiers.org/kegg.compound/C00076> , <https://identifiers.org/hmdb/HMDB0000464> ;
        wp:source         <https://identifiers.org/hmdb/HMDB0000464> ;
        wp:target         <https://identifiers.org/kegg.compound/C00076> .

<https://identifiers.org/ncbigene/7124>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "TNFalpha" ;
        dc:identifier       <https://identifiers.org/ncbigene/7124> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "7124" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2447_r139972/WP/Interaction/ida7f01dcb> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/WP/Interaction/id94a8676c> , <https://identifiers.org/wikipathways/WP2447_r139972> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000232810> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/7124> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/TNF> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q5STB3> , <https://identifiers.org/uniprot/P01375> , <https://identifiers.org/uniprot/A0A8V8TNL2> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/c5456> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/d3da2> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P01375> , <http://purl.uniprot.org/uniprot/Q5STB3> , <http://purl.uniprot.org/uniprot/A0A8V8TNL2> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/7124> .

<https://identifiers.org/pubmed/21569822>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "21569822" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2447_r139972> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/21569822> .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/WP/Interaction/a5b33>
        rdf:type          wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2447_r139972> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/a5b33> ;
        wp:participants   <https://identifiers.org/chebi/CHEBI:26523> , <https://identifiers.org/hmdb/HMDB0001039> .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/WP/Interaction/id751c8da1>
        rdf:type          wp:Inhibition , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2447_r139972> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id751c8da1> ;
        wp:participants   <https://identifiers.org/ncbigene/79139> , <https://identifiers.org/ncbigene/6647> ;
        wp:source         <https://identifiers.org/ncbigene/6647> ;
        wp:target         <https://identifiers.org/ncbigene/79139> .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/WP/Interaction/idd6d367a2>
        rdf:type          wp:Catalysis , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2447_r139972> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idd6d367a2> ;
        wp:participants   <https://identifiers.org/ncbigene/2876> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/WP/Interaction/id69b8a250> ;
        wp:source         <https://identifiers.org/ncbigene/2876> ;
        wp:target         <http://rdf.wikipathways.org/Pathway/WP2447_r139972/WP/Interaction/id69b8a250> .

<https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=svg&pwTitle=Pathway:WP2447&oldid=139972>
        rdf:type        foaf:Image ;
        dcterms:format  "image/svg+xml" .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/WP/Interaction/id2bad9ea5>
        rdf:type          wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2447_r139972> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id2bad9ea5> ;
        wp:participants   <https://identifiers.org/ncbigene/5630> , <https://identifiers.org/ncbigene/4744> .

<https://identifiers.org/wikipathways/WP382>
        rdf:type            wp:Pathway , wp:DataNode ;
        rdfs:label          "MAPK signaling pathway" ;
        dc:identifier       <https://identifiers.org/wikipathways/WP382> ;
        dc:source           "WikiPathways" ;
        dcterms:identifier  "WP382" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2447_r139972> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/f2714> ;
        foaf:page           <https://www.wikipathways.org/instance/WP382> .

<https://identifiers.org/ncbigene/637>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "BID" ;
        dc:identifier       <https://identifiers.org/ncbigene/637> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "637" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/WP/Interaction/idf5c9eb78> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000015475> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/637> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/BID> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A8ASI8> , <https://identifiers.org/uniprot/B2ZP79> , <https://identifiers.org/uniprot/P55957> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/e5005> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A8ASI8> , <http://purl.uniprot.org/uniprot/P55957> , <http://purl.uniprot.org/uniprot/B2ZP79> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/637> .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/WP/Interaction/id85aed399>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2447_r139972> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id85aed399> ;
        wp:participants   <https://identifiers.org/hmdb/HMDB0003378> ;
        wp:source         <https://identifiers.org/hmdb/HMDB0003378> ;
        wp:target         <https://identifiers.org/hmdb/HMDB0003378> .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/ComplexBinding/b3274>
        rdf:type          wp:ComplexBinding , wp:Binding , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2447_r139972> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Group/b3274> ;
        wp:participants   <https://identifiers.org/ncbigene/5605> , <https://identifiers.org/ncbigene/5608> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Complex/b3274> .

<https://identifiers.org/hmdb/HMDB0000464>
        rdf:type            wp:DataNode , wp:Metabolite ;
        rdfs:label          "Ca²⁺" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/BHPQYMZQTOCNFJ-UHFFFAOYSA-N> ;
        dc:identifier       <https://identifiers.org/hmdb/HMDB0000464> ;
        dc:source           "HMDB" ;
        dcterms:identifier  "HMDB0000464" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2447_r139972/WP/Interaction/idd46b0994> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/WP/Interaction/ide9959d31> , <https://identifiers.org/wikipathways/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/WP/Interaction/id69896d2b> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:29108> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/266> ;
        wp:bdbHmdb          <https://identifiers.org/hmdb/HMDB0000464> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/BHPQYMZQTOCNFJ-UHFFFAOYSA-N> ;
        wp:bdbKeggCompound  <https://identifiers.org/kegg.compound/C00076> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID271> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q23905776> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/e777d> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/ff83a> ;
        foaf:page           <http://www.hmdb.ca/metabolites/HMDB0000464> .

<https://identifiers.org/ncbigene/317>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "APAF1" ;
        dc:identifier       <https://identifiers.org/ncbigene/317> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "317" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2447_r139972/WP/Interaction/id136847e9> , <https://identifiers.org/wikipathways/WP2447_r139972> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000120868> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/317> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/APAF1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/O14727> , <https://identifiers.org/uniprot/F8VNZ0> , <https://identifiers.org/uniprot/C9JLV4> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/b676b> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/O14727> , <http://purl.uniprot.org/uniprot/F8VNZ0> , <http://purl.uniprot.org/uniprot/C9JLV4> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/317> .

<https://identifiers.org/ncbigene/7157>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "TP53" ;
        dc:identifier       <https://identifiers.org/ncbigene/7157> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "7157" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2447_r139972> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000141510> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/7157> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/TP53> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A087X1Q1> , <https://identifiers.org/uniprot/S4R334> , <https://identifiers.org/uniprot/E9PFT5> , <https://identifiers.org/uniprot/E7EMR6> , <https://identifiers.org/uniprot/A0A087WT22> , <https://identifiers.org/uniprot/K7PPA8> , <https://identifiers.org/uniprot/A0A0U1RQC9> , <https://identifiers.org/uniprot/I3L0W9> , <https://identifiers.org/uniprot/E7ESS1> , <https://identifiers.org/uniprot/E9PCY9> , <https://identifiers.org/uniprot/E7EQX7> , <https://identifiers.org/uniprot/H2EHT1> , <https://identifiers.org/uniprot/J3KP33> , <https://identifiers.org/uniprot/P04637> , <https://identifiers.org/uniprot/A0A087WXZ1> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/b6e6e> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/H2EHT1> , <http://purl.uniprot.org/uniprot/A0A0U1RQC9> , <http://purl.uniprot.org/uniprot/S4R334> , <http://purl.uniprot.org/uniprot/E7EMR6> , <http://purl.uniprot.org/uniprot/K7PPA8> , <http://purl.uniprot.org/uniprot/E9PCY9> , <http://purl.uniprot.org/uniprot/P04637> , <http://purl.uniprot.org/uniprot/A0A087WXZ1> , <http://purl.uniprot.org/uniprot/A0A087WT22> , <http://purl.uniprot.org/uniprot/E7ESS1> , <http://purl.uniprot.org/uniprot/A0A087X1Q1> , <http://purl.uniprot.org/uniprot/J3KP33> , <http://purl.uniprot.org/uniprot/E7EQX7> , <http://purl.uniprot.org/uniprot/I3L0W9> , <http://purl.uniprot.org/uniprot/E9PFT5> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/7157> .

<https://identifiers.org/wikipathways/WP254>
        rdf:type            wp:DataNode , wp:Pathway ;
        rdfs:label          "Apoptosis" ;
        dc:identifier       <https://identifiers.org/wikipathways/WP254> ;
        dc:source           "WikiPathways" ;
        dcterms:identifier  "WP254" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2447_r139972> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/abf1b> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/e3646> ;
        foaf:page           <https://www.wikipathways.org/instance/WP254> .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/WP/Interaction/idb3aea929>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2447_r139972> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idb3aea929> ;
        wp:participants   <https://identifiers.org/ncbigene/4747> , <https://identifiers.org/ncbigene/1432> ;
        wp:source         <https://identifiers.org/ncbigene/1432> ;
        wp:target         <https://identifiers.org/ncbigene/4747> .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/WP/Interaction/id3cd23c9>
        rdf:type          wp:Conversion , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2447_r139972> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id3cd23c9> ;
        wp:participants   <https://identifiers.org/hmdb/HMDB0000148> ;
        wp:source         <https://identifiers.org/hmdb/HMDB0000148> ;
        wp:target         <https://identifiers.org/hmdb/HMDB0000148> .

<https://identifiers.org/pmc/PMC8170991>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed Central" ;
        dcterms:identifier  "PMC8170991" ;
        cito:cites          <https://identifiers.org/wikipathways/WP2447> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/PMC8170991> .

<https://identifiers.org/pmc/PMC9524193>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed Central" ;
        dcterms:identifier  "PMC9524193" ;
        cito:cites          <https://identifiers.org/wikipathways/WP2447> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/PMC9524193> .

<https://doi.org/10.1016%2Fj.compbiomed.2021.104243>
        rdf:type            wp:PublicationReference ;
        dc:source           "DOI" ;
        dcterms:identifier  "10.1016/j.compbiomed.2021.104243" ;
        cito:cites          <https://identifiers.org/wikipathways/WP2447> .

<https://identifiers.org/ncbigene/572>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "BAD" ;
        dc:identifier       <https://identifiers.org/ncbigene/572> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "572" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2447_r139972> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000002330> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/572> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/BAD> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/F5H1R6> , <https://identifiers.org/uniprot/Q92934> , <https://identifiers.org/uniprot/F5H3B1> , <https://identifiers.org/uniprot/F5GYS3> , <https://identifiers.org/uniprot/A8MXU7> , <https://identifiers.org/uniprot/A0A024R562> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/e66bb> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A8MXU7> , <http://purl.uniprot.org/uniprot/F5H1R6> , <http://purl.uniprot.org/uniprot/A0A024R562> , <http://purl.uniprot.org/uniprot/F5GYS3> , <http://purl.uniprot.org/uniprot/Q92934> , <http://purl.uniprot.org/uniprot/F5H3B1> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/572> .

<https://identifiers.org/ncbigene/836>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "CASP3" ;
        dc:identifier       <https://identifiers.org/ncbigene/836> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "836" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/WP/Interaction/id9999669c> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000164305> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/836> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/CASP3> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A8MVM1> , <https://identifiers.org/uniprot/A0A8V8TPU5> , <https://identifiers.org/uniprot/P42574> , <https://identifiers.org/uniprot/C9JXR7> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/a20e1> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P42574> , <http://purl.uniprot.org/uniprot/C9JXR7> , <http://purl.uniprot.org/uniprot/A8MVM1> , <http://purl.uniprot.org/uniprot/A0A8V8TPU5> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/836> .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/WP/Interaction/ide9959d31>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2447_r139972> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/ide9959d31> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/e9754> ;
        wp:participants   <https://identifiers.org/hmdb/HMDB0000464> , <https://identifiers.org/hmdb/HMDB0000148> , <https://identifiers.org/ncbigene/2890> ;
        wp:source         <https://identifiers.org/hmdb/HMDB0000148> , <https://identifiers.org/ncbigene/2890> ;
        wp:target         <https://identifiers.org/hmdb/HMDB0000464> .

<https://identifiers.org/ncbigene/4744>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "NEFH" ;
        dc:identifier       <https://identifiers.org/ncbigene/4744> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "4744" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/WP/Interaction/id2bad9ea5> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000100285> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/4744> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/NEFH> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/P12036> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/c4c17> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P12036> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/4744> .

<https://identifiers.org/ncbigene/4217>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "ASK1" ;
        dc:identifier       <https://identifiers.org/ncbigene/4217> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "4217" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2447_r139972/WP/Interaction/id1de00d7a> , <https://identifiers.org/wikipathways/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/WP/Interaction/id142719ee> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000197442> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/4217> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/MAP3K5> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A8V8TMH5> , <https://identifiers.org/uniprot/Q99683> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/f3615> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/fbdfc> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q99683> , <http://purl.uniprot.org/uniprot/A0A8V8TMH5> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/4217> .

<https://identifiers.org/ncbigene/598>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "BCL2L1" ;
        dc:identifier       <https://identifiers.org/ncbigene/598> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "598" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2447_r139972> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000171552> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/598> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/BCL2L1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A7I2V597> , <https://identifiers.org/uniprot/A0A0S2Z3C5> , <https://identifiers.org/uniprot/Q5TE63> , <https://identifiers.org/uniprot/Q5QP56> , <https://identifiers.org/uniprot/Q9H1R6> , <https://identifiers.org/uniprot/Q5TE64> , <https://identifiers.org/uniprot/Q5QP59> , <https://identifiers.org/uniprot/Q07817> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/fd4bd> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A7I2V597> , <http://purl.uniprot.org/uniprot/Q5TE63> , <http://purl.uniprot.org/uniprot/Q5TE64> , <http://purl.uniprot.org/uniprot/Q9H1R6> , <http://purl.uniprot.org/uniprot/Q5QP59> , <http://purl.uniprot.org/uniprot/Q5QP56> , <http://purl.uniprot.org/uniprot/A0A0S2Z3C5> , <http://purl.uniprot.org/uniprot/Q07817> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/598> .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/WP/Interaction/ida7f01dcb>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2447_r139972> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/ida7f01dcb> ;
        wp:participants   <https://identifiers.org/ncbigene/7124> ;
        wp:source         <https://identifiers.org/ncbigene/7124> ;
        wp:target         <https://identifiers.org/ncbigene/7124> .

<https://identifiers.org/ncbigene/5608>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "MKK6" ;
        dc:identifier       <https://identifiers.org/ncbigene/5608> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "5608" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Complex/b3274> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000108984> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/5608> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/MAP2K6> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A8K3Y2> , <https://identifiers.org/uniprot/A0A0A0MRF7> , <https://identifiers.org/uniprot/P52564> , <https://identifiers.org/uniprot/A0A024R8K3> , <https://identifiers.org/uniprot/K7ELM6> , <https://identifiers.org/uniprot/K7EIW3> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/c1091> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A0A0MRF7> , <http://purl.uniprot.org/uniprot/P52564> , <http://purl.uniprot.org/uniprot/A8K3Y2> , <http://purl.uniprot.org/uniprot/A0A024R8K3> , <http://purl.uniprot.org/uniprot/K7ELM6> , <http://purl.uniprot.org/uniprot/K7EIW3> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/5608> .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/WP/Interaction/idb3584e45>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2447_r139972> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idb3584e45> ;
        wp:participants   <https://identifiers.org/hmdb/HMDB0003378> ;
        wp:source         <https://identifiers.org/hmdb/HMDB0003378> ;
        wp:target         <https://identifiers.org/hmdb/HMDB0003378> .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/WP/Interaction/id1e1bab7c>
        rdf:type          wp:Catalysis , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2447_r139972> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id1e1bab7c> ;
        wp:participants   <https://identifiers.org/ncbigene/4842> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/WP/Interaction/id2dedab80> ;
        wp:source         <https://identifiers.org/ncbigene/4842> ;
        wp:target         <http://rdf.wikipathways.org/Pathway/WP2447_r139972/WP/Interaction/id2dedab80> .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/WP/Interaction/idd37d0e73>
        rdf:type          wp:Interaction , wp:DirectedInteraction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2447_r139972> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id676d67d3> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/idd37d0e73> ;
        wp:participants   <https://identifiers.org/hmdb/HMDB0000657> , <https://identifiers.org/ncbigene/6647> , <https://identifiers.org/ncbigene/9973> ;
        wp:source         <https://identifiers.org/hmdb/HMDB0000657> , <https://identifiers.org/ncbigene/9973> ;
        wp:target         <https://identifiers.org/ncbigene/6647> .

<https://identifiers.org/hmdb/HMDB0002168>
        rdf:type            wp:DataNode , wp:Metabolite ;
        rdfs:label          "O2-" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/OUUQCZGPVNCOIJ-UHFFFAOYSA-N> ;
        dc:identifier       <https://identifiers.org/hmdb/HMDB0002168> ;
        dc:source           "HMDB" ;
        dcterms:identifier  "HMDB0002168" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2447_r139972/WP/Interaction/id7c9c96e3> , <https://identifiers.org/wikipathways/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/WP/Interaction/id7d4f73cd> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/WP/Interaction/bcc7f> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:18421> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/4514331> ;
        wp:bdbHmdb          <https://identifiers.org/hmdb/HMDB0002168> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/OUUQCZGPVNCOIJ-UHFFFAOYSA-M> ;
        wp:bdbKeggCompound  <https://identifiers.org/kegg.compound/C00704> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID5359597> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q69521260> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/f6deb> ;
        foaf:page           <http://www.hmdb.ca/metabolites/HMDB0002168> .

<https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=png&pwTitle=Pathway:WP2447&oldid=139972>
        rdf:type        foaf:Image ;
        dcterms:format  "image/png" .

<https://identifiers.org/ncbigene/5630>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "PRPH" ;
        dc:identifier       <https://identifiers.org/ncbigene/5630> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "5630" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/WP/Interaction/id2bad9ea5> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000135406> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/5630> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/PRPH> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/F8W835> , <https://identifiers.org/uniprot/P41219> , <https://identifiers.org/uniprot/H7C5W5> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/ffa60> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P41219> , <http://purl.uniprot.org/uniprot/H7C5W5> , <http://purl.uniprot.org/uniprot/F8W835> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/5630> .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/WP/Interaction/id94a8676c>
        rdf:type          wp:Interaction , wp:DirectedInteraction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2447_r139972> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id28b00f54> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id94a8676c> ;
        wp:participants   <https://identifiers.org/ncbigene/7124> , <https://identifiers.org/ncbigene/1616> , <https://identifiers.org/ncbigene/7132> ;
        wp:source         <https://identifiers.org/ncbigene/7132> , <https://identifiers.org/ncbigene/7124> ;
        wp:target         <https://identifiers.org/ncbigene/1616> .

<https://identifiers.org/ncbigene/5530>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "PPP3CA" ;
        dc:identifier       <https://identifiers.org/ncbigene/5530> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "5530" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Complex/d820d> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000138814> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/5530> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/PPP3CA> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/E9PPC8> , <https://identifiers.org/uniprot/E7ETC2> , <https://identifiers.org/uniprot/A0A0S2Z4B5> , <https://identifiers.org/uniprot/Q08209> , <https://identifiers.org/uniprot/E9PK68> , <https://identifiers.org/uniprot/H0YAB4> , <https://identifiers.org/uniprot/A0A0S2Z4C6> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/a173c> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A0S2Z4C6> , <http://purl.uniprot.org/uniprot/E9PK68> , <http://purl.uniprot.org/uniprot/Q08209> , <http://purl.uniprot.org/uniprot/E9PPC8> , <http://purl.uniprot.org/uniprot/A0A0S2Z4B5> , <http://purl.uniprot.org/uniprot/E7ETC2> , <http://purl.uniprot.org/uniprot/H0YAB4> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/5530> .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/WP/Interaction/id8c85cf83>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2447_r139972> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id8c85cf83> ;
        wp:participants   <https://identifiers.org/hmdb/HMDB0003378> ;
        wp:source         <https://identifiers.org/hmdb/HMDB0003378> ;
        wp:target         <https://identifiers.org/hmdb/HMDB0003378> .

<https://identifiers.org/wikipathways/WP2447>
        pav:hasVersion  <https://identifiers.org/wikipathways/WP2447_r139972> .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/WP/Interaction/id7d4f73cd>
        rdf:type          wp:Conversion , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2447_r139972> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id7d4f73cd> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/ida154c80d> ;
        wp:participants   <https://identifiers.org/hmdb/HMDB0002179> , <https://identifiers.org/hmdb/HMDB0003378> , <https://identifiers.org/hmdb/HMDB0002168> ;
        wp:source         <https://identifiers.org/hmdb/HMDB0002168> , <https://identifiers.org/hmdb/HMDB0003378> ;
        wp:target         <https://identifiers.org/hmdb/HMDB0002179> .

<https://identifiers.org/wikipathways/WP2447_r139972>
        rdf:type                skos:Collection , wp:Pathway ;
        dc:identifier           <https://identifiers.org/wikipathways/WP2447> ;
        dc:source               "WikiPathways" ;
        dc:title                "Amyotrophic lateral sclerosis (ALS)"@en ;
        dcterms:description     "Amyotrophic lateral sclerosis (ALS) is a progressive, lethal, degenerative disorder of motor neurons. The hallmark of this disease is the selective death of motor neurons in the brain and spinal cord, leading to paralysis of voluntary muscles. Mutant superoxide dismutase 1 (SOD1), as seen in some familial ALS (FALS) cases, is unstable, forming aggregates in the motor neuron cytoplasm, axoplasm and mitochondria. Within mitochondria, mutant SOD1 may interfere with the anti-apoptotic function of Bcl-2, affect mitochondrial import by interfering with the translocation machinery (TOM/TIM), and generate toxic free radicals (ROS). Reactive oxygen species (ROS), produced within mitochondria, inhibit the function of EAAT2, the main glial glutamate transporter protein, responsible for most of the reuptake of synaptically released glutamate. Glutamate excess increases intracellular calcium, which enhances oxidative stress and mitochondrial damage. Mutant SOD1 can also trigger oxidative reactions , which can then cause damage through the formation of hydroxyl radicals or via nitration of tyrosine residues on proteins. Nitration may target neurofilament proteins, affecting axonal transport. Collectively, these mechanisms are predicted to disturb cellular homeostasis, ultimately triggering motor neuron death.\n\nProteins on this pathway have targeted assays available via the [CPTAC Assay Portal](https://assays.cancer.gov/available_assays?wp_id=WP2447)." ;
        dcterms:identifier      "WP2447" ;
        dcterms:references      <https://identifiers.org/pubmed/21569822> ;
        cito:cites              <https://identifiers.org/pubmed/21569822> ;
        wp:cellTypeOntologyTag  obo:CL_0000127 , obo:CL_0000129 , obo:CL_0000540 ;
        wp:diseaseOntologyTag   obo:DOID_332 ;
        wp:isAbout              <http://rdf.wikipathways.org/Pathway/WP2447_r139972> ;
        wp:ontologyTag          wp:Curation:RareDiseases , obo:DOID_332 , wp:Curation:AnalysisCollection , obo:PW_0000013 , obo:CL_0000540 , obo:CL_0000127 , obo:CL_0000129 ;
        wp:organism             obo:NCBITaxon_9606 ;
        wp:organismName         "Homo sapiens" ;
        wp:pathwayOntologyTag   obo:PW_0000013 ;
        foaf:img                <https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=png&pwTitle=Pathway:WP2447&oldid=139972> , <https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=svg&pwTitle=Pathway:WP2447&oldid=139972> ;
        foaf:page               <http://www.wikipathways.org/instance/WP2447_r139972> .

<https://identifiers.org/hmdb/HMDB0000148>
        rdf:type            wp:Metabolite , wp:DataNode ;
        rdfs:label          "L-Glutamic acid" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/WHUUTDBJXJRKMK-VKHMYHEASA-N> ;
        dc:identifier       <https://identifiers.org/hmdb/HMDB0000148> ;
        dc:source           "HMDB" ;
        dcterms:identifier  "HMDB0000148" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2447_r139972/WP/Interaction/ide9959d31> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/WP/Interaction/id3cd23c9> , <https://identifiers.org/wikipathways/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/WP/Interaction/idde65c6be> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:16015> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/30572> ;
        wp:bdbHmdb          <https://identifiers.org/hmdb/HMDB0000148> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/WHUUTDBJXJRKMK-VKHMYHEASA-N> ;
        wp:bdbKeggCompound  <https://identifiers.org/kegg.compound/C00025> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID33032> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q26995161> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/ba994> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/f04ac> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/f9d1b> ;
        foaf:page           <http://www.hmdb.ca/metabolites/HMDB0000148> .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/WP/Interaction/ida90aa669>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2447_r139972> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/ida90aa669> ;
        wp:participants   <https://identifiers.org/ncbigene/842> , <https://identifiers.org/uniprot/P01034> ;
        wp:source         <https://identifiers.org/uniprot/P01034> ;
        wp:target         <https://identifiers.org/ncbigene/842> .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/ComplexBinding/d820d>
        rdf:type          wp:ComplexBinding , wp:Binding , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2447_r139972> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Group/d820d> ;
        wp:participants   <https://identifiers.org/ncbigene/5533> , <https://identifiers.org/ncbigene/5530> , <https://identifiers.org/ncbigene/5532> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Complex/d820d> .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/WP/Interaction/id6a75a338>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2447_r139972> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id6a75a338> ;
        wp:participants   <https://identifiers.org/ncbigene/4741> , <https://identifiers.org/hmdb/HMDB0001039> ;
        wp:source         <https://identifiers.org/hmdb/HMDB0001039> ;
        wp:target         <https://identifiers.org/ncbigene/4741> .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/WP/Interaction/id4993787b>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2447_r139972> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id4993787b> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id8abdb052> ;
        wp:participants   <https://identifiers.org/ncbigene/6647> , <https://identifiers.org/ncbigene/4741> , <https://identifiers.org/hmdb/HMDB0002179> ;
        wp:source         <https://identifiers.org/hmdb/HMDB0002179> , <https://identifiers.org/ncbigene/6647> ;
        wp:target         <https://identifiers.org/ncbigene/4741> .

<https://identifiers.org/chebi/CHEBI:26523>
        rdf:type            wp:DataNode , wp:Metabolite ;
        rdfs:label          "Reactive oxygen species (ROS)" , "Reactive oxygen species  (ROS)" ;
        dc:identifier       <https://identifiers.org/chebi/CHEBI:26523> ;
        dc:source           "ChEBI" ;
        dcterms:identifier  "CHEBI:26523" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2447_r139972/WP/Interaction/a5b33> , <https://identifiers.org/wikipathways/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/WP/Interaction/id8197ddde> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/WP/Interaction/id719c925> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/WP/Interaction/bcc7f> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/WP/Interaction/id6fc14d0a> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:26523> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q424361> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/b24b0> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/de780> ;
        foaf:page           <https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:26523> .

<https://identifiers.org/ncbigene/842>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "CASP9" ;
        dc:identifier       <https://identifiers.org/ncbigene/842> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "842" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2447_r139972/WP/Interaction/id136847e9> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/WP/Interaction/ida90aa669> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/WP/Interaction/id9999669c> , <https://identifiers.org/wikipathways/WP2447_r139972> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000132906> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/842> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/CASP9> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/F8VVS7> , <https://identifiers.org/uniprot/A0A087WX72> , <https://identifiers.org/uniprot/F8VWA5> , <https://identifiers.org/uniprot/Q5JRU8> , <https://identifiers.org/uniprot/Q5JRU2> , <https://identifiers.org/uniprot/H0Y3S8> , <https://identifiers.org/uniprot/P55211> , <https://identifiers.org/uniprot/H0Y6Y2> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/b7cd3> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/H0Y3S8> , <http://purl.uniprot.org/uniprot/A0A087WX72> , <http://purl.uniprot.org/uniprot/P55211> , <http://purl.uniprot.org/uniprot/F8VVS7> , <http://purl.uniprot.org/uniprot/F8VWA5> , <http://purl.uniprot.org/uniprot/Q5JRU2> , <http://purl.uniprot.org/uniprot/Q5JRU8> , <http://purl.uniprot.org/uniprot/H0Y6Y2> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/842> .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/WP/Interaction/id142719ee>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2447_r139972> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id142719ee> ;
        wp:participants   <https://identifiers.org/ncbigene/4217> , <https://identifiers.org/ncbigene/1616> ;
        wp:source         <https://identifiers.org/ncbigene/1616> ;
        wp:target         <https://identifiers.org/ncbigene/4217> .

<https://identifiers.org/ncbigene/1432>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "p38" ;
        dc:identifier       <https://identifiers.org/ncbigene/1432> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "1432" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2447_r139972/WP/Interaction/idb3aea929> , <https://identifiers.org/wikipathways/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/WP/Interaction/id1de00d7a> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000112062> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/1432> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/MAPK14> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/H7C4E2> , <https://identifiers.org/uniprot/E7EX54> , <https://identifiers.org/uniprot/Q16539> , <https://identifiers.org/uniprot/B5TY33> , <https://identifiers.org/uniprot/B4E0K5> , <https://identifiers.org/uniprot/L7RSM2> , <https://identifiers.org/uniprot/A0A024RD15> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/a22a5> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/H7C4E2> , <http://purl.uniprot.org/uniprot/L7RSM2> , <http://purl.uniprot.org/uniprot/B5TY33> , <http://purl.uniprot.org/uniprot/B4E0K5> , <http://purl.uniprot.org/uniprot/A0A024RD15> , <http://purl.uniprot.org/uniprot/E7EX54> , <http://purl.uniprot.org/uniprot/Q16539> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/1432> .

<https://identifiers.org/ncbigene/5868>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "RAB5A" ;
        dc:identifier       <https://identifiers.org/ncbigene/5868> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "5868" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2447_r139972/WP/Interaction/id8d950ddc> , <https://identifiers.org/wikipathways/WP2447_r139972> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000144566> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/5868> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/RAB5A> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/F8WD79> , <https://identifiers.org/uniprot/A0A024R2K1> , <https://identifiers.org/uniprot/F8WCY6> , <https://identifiers.org/uniprot/P20339> , <https://identifiers.org/uniprot/C9J3X8> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/b4635> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/C9J3X8> , <http://purl.uniprot.org/uniprot/F8WD79> , <http://purl.uniprot.org/uniprot/F8WCY6> , <http://purl.uniprot.org/uniprot/A0A024R2K1> , <http://purl.uniprot.org/uniprot/P20339> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/5868> .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/WP/Interaction/id6fc14d0a>
        rdf:type          wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2447_r139972> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id6fc14d0a> ;
        wp:participants   <https://identifiers.org/chebi/CHEBI:26523> , <https://identifiers.org/hmdb/HMDB0002179> .

<http://rdf.wikipathways.org/Pathway/WP2447_r139972/WP/Interaction/id8d950ddc>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2447_r139972> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2447_r139972/Interaction/id8d950ddc> ;
        wp:participants   <https://identifiers.org/ncbigene/5868> , <https://identifiers.org/ncbigene/57679> ;
        wp:source         <https://identifiers.org/ncbigene/57679> ;
        wp:target         <https://identifiers.org/ncbigene/5868> .

<https://identifiers.org/ncbigene/6647>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "SOD1" ;
        dc:identifier       <https://identifiers.org/ncbigene/6647> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "6647" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2447_r139972/WP/Interaction/id7c9c96e3> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/WP/Interaction/id117c419f> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/WP/Interaction/id8197ddde> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/WP/Interaction/id751c8da1> , <https://identifiers.org/wikipathways/WP2447_r139972> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/WP/Interaction/id4993787b> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/WP/Interaction/idd37d0e73> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000142168> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/6647> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/SOD1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/V9HWC9> , <https://identifiers.org/uniprot/H7BYH4> , <https://identifiers.org/uniprot/P00441> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/bcd7f> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/f8e7a> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/a14b7> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/fefdb> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P00441> , <http://purl.uniprot.org/uniprot/V9HWC9> , <http://purl.uniprot.org/uniprot/H7BYH4> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/6647> .

<https://identifiers.org/hmdb/HMDB0003125>
        rdf:type            wp:Metabolite , wp:DataNode ;
        rdfs:label          "H₂O₂" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/MHAJPDPJQMAIIY-UHFFFAOYSA-N> ;
        dc:identifier       <https://identifiers.org/hmdb/HMDB0003125> ;
        dc:source           "HMDB" ;
        dcterms:identifier  "HMDB0003125" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2447_r139972/WP/Interaction/id69b8a250> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/WP/Interaction/id117c419f> , <http://rdf.wikipathways.org/Pathway/WP2447_r139972/WP/Interaction/id7c9c96e3> , <https://identifiers.org/wikipathways/WP2447_r139972> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:16240> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/763> ;
        wp:bdbHmdb          <https://identifiers.org/hmdb/HMDB0003125> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/MHAJPDPJQMAIIY-UHFFFAOYSA-N> ;
        wp:bdbKeggCompound  <https://identifiers.org/kegg.compound/C00027> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID784> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q171877> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2447_r139972/DataNode/a0090> ;
        foaf:page           <http://www.hmdb.ca/metabolites/HMDB0003125> .
