@prefix biopax:  <http://www.biopax.org/release/biopax-level3.owl#> .
@prefix cito:    <http://purl.org/spar/cito/> .
@prefix dc:      <http://purl.org/dc/elements/1.1/> .
@prefix dcterms: <http://purl.org/dc/terms/> .
@prefix foaf:    <http://xmlns.com/foaf/0.1/> .
@prefix freq:    <http://purl.org/cld/freq/> .
@prefix gpml:    <http://vocabularies.wikipathways.org/gpml#> .
@prefix obo:     <http://purl.obolibrary.org/obo/> .
@prefix owl:     <http://www.w3.org/2002/07/owl#> .
@prefix pav:     <http://purl.org/pav/> .
@prefix prov:    <http://www.w3.org/ns/prov#> .
@prefix rdf:     <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix rdfs:    <http://www.w3.org/2000/01/rdf-schema#> .
@prefix skos:    <http://www.w3.org/2004/02/skos/core#> .
@prefix void:    <http://rdfs.org/ns/void#> .
@prefix wp:      <http://vocabularies.wikipathways.org/wp#> .
@prefix wprdf:   <http://rdf.wikipathways.org/> .
@prefix xsd:     <http://www.w3.org/2001/XMLSchema#> .

<https://identifiers.org/wikipathways/WP608>
        pav:hasVersion  <https://identifiers.org/wikipathways/WP608_r142078> .

<https://identifiers.org/mirbase/MI0000652>
        rdf:type            wp:DataNode , wp:Rna ;
        rdfs:label          "mmu-mir-1-2" ;
        dc:identifier       <https://identifiers.org/mirbase/MI0000652> ;
        dc:source           "miRBase Sequence" ;
        dcterms:identifier  "MI0000652" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP608_r142078> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSMUSG00000106348> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/723959> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP608_r142078/DataNode/a18de> ;
        foaf:page           <https://www.mirbase.org/cgi-bin/mirna_entry.pl?acc=MI0000652> .

<https://identifiers.org/ncbigene/54352>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "Irx5" ;
        dc:identifier       <https://identifiers.org/ncbigene/54352> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "54352" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP608_r142078> , <http://rdf.wikipathways.org/Pathway/WP608_r142078/WP/Interaction/c5eb9> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSMUSG00000031737> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/54352> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A1B0GR17> , <https://identifiers.org/uniprot/Q9JKQ4> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP608_r142078/DataNode/e352b> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A1B0GR17> , <http://purl.uniprot.org/uniprot/Q9JKQ4> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/54352> .

<https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=png&pwTitle=Pathway:WP608&oldid=142078>
        rdf:type        foaf:Image ;
        dcterms:format  "image/png" .

<http://rdf.wikipathways.org/Pathway/WP608_r142078/WP/Interaction/c5eb9>
        rdf:type          wp:Inhibition , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP608_r142078> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP608_r142078/Interaction/c5eb9> ;
        wp:participants   <https://identifiers.org/ncbigene/16508> , <https://identifiers.org/ncbigene/54352> ;
        wp:source         <https://identifiers.org/ncbigene/54352> ;
        wp:target         <https://identifiers.org/ncbigene/16508> .

<https://identifiers.org/ncbigene/15111>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "Hand2" ;
        dc:identifier       <https://identifiers.org/ncbigene/15111> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "15111" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP608_r142078> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSMUSG00000038193> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/15111> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q61039> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP608_r142078/DataNode/f3a5a> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q61039> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/15111> .

<https://identifiers.org/ncbigene/16508>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "Kcnd2" ;
        dc:identifier       <https://identifiers.org/ncbigene/16508> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "16508" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP608_r142078> , <http://rdf.wikipathways.org/Pathway/WP608_r142078/WP/Interaction/c5eb9> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSMUSG00000060882> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/16508> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q9Z0V2> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP608_r142078/DataNode/d7557> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q9Z0V2> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/16508> .

<https://identifiers.org/pubmed/18270516>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "18270516" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP608_r142078> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/18270516> .

<https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=svg&pwTitle=Pathway:WP608&oldid=142078>
        rdf:type        foaf:Image ;
        dcterms:format  "image/svg+xml" .

obo:NCBITaxon_10090  obo:NCIT_C179773  "10090" .

<https://identifiers.org/wikipathways/WP608_r142078>
        rdf:type               wp:Pathway , skos:Collection ;
        dc:identifier          <https://identifiers.org/wikipathways/WP608> ;
        dc:source              "WikiPathways" ;
        dc:title               "miR-1 in cardiac development"@en ;
        dcterms:description    "This pathway is an adaptation from Figure 2.a in Stefani et al. (2008). miR-1 regulates cardiac morphogenesis by optimizing the level of the HAND2 transcription factor. Electric conduction is abnormal in mice that lack miR-1 as a consequence of de-inhibition of IRX5, a homeodomain-containing transcription factor that represses the expression of the KCND2 potassium channel." ;
        dcterms:identifier     "WP608" ;
        dcterms:references     <https://identifiers.org/pubmed/18270516> ;
        cito:cites             <https://identifiers.org/pubmed/18270516> ;
        wp:isAbout             <http://rdf.wikipathways.org/Pathway/WP608_r142078> ;
        wp:ontologyTag         obo:PW_0000808 , wp:Curation:AnalysisCollection ;
        wp:organism            obo:NCBITaxon_10090 ;
        wp:organismName        "Mus musculus" ;
        wp:pathwayOntologyTag  obo:PW_0000808 ;
        foaf:img               <https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=svg&pwTitle=Pathway:WP608&oldid=142078> , <https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=png&pwTitle=Pathway:WP608&oldid=142078> ;
        foaf:page              <http://www.wikipathways.org/instance/WP608_r142078> .

<https://identifiers.org/mirbase/MI0000139>
        rdf:type            wp:Rna , wp:DataNode ;
        rdfs:label          "mmu-mir-1-1" ;
        dc:identifier       <https://identifiers.org/mirbase/MI0000139> ;
        dc:source           "miRBase Sequence" ;
        dcterms:identifier  "MI0000139" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP608_r142078> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSMUSG00000070144> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/387136> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP608_r142078/DataNode/bdc06> ;
        foaf:page           <https://www.mirbase.org/cgi-bin/mirna_entry.pl?acc=MI0000139> .
