@prefix biopax:  <http://www.biopax.org/release/biopax-level3.owl#> .
@prefix cito:    <http://purl.org/spar/cito/> .
@prefix dc:      <http://purl.org/dc/elements/1.1/> .
@prefix dcterms: <http://purl.org/dc/terms/> .
@prefix foaf:    <http://xmlns.com/foaf/0.1/> .
@prefix freq:    <http://purl.org/cld/freq/> .
@prefix gpml:    <http://vocabularies.wikipathways.org/gpml#> .
@prefix obo:     <http://purl.obolibrary.org/obo/> .
@prefix owl:     <http://www.w3.org/2002/07/owl#> .
@prefix pav:     <http://purl.org/pav/> .
@prefix prov:    <http://www.w3.org/ns/prov#> .
@prefix rdf:     <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix rdfs:    <http://www.w3.org/2000/01/rdf-schema#> .
@prefix skos:    <http://www.w3.org/2004/02/skos/core#> .
@prefix void:    <http://rdfs.org/ns/void#> .
@prefix wp:      <http://vocabularies.wikipathways.org/wp#> .
@prefix wprdf:   <http://rdf.wikipathways.org/> .
@prefix xsd:     <http://www.w3.org/2001/XMLSchema#> .

<https://identifiers.org/ensembl/ENSG00000166278>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "C2" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000166278> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000166278" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP5560_r139562> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000166278> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/717> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/C2> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/C9JYQ5> , <https://identifiers.org/uniprot/H0Y868> , <https://identifiers.org/uniprot/Q5JP69> , <https://identifiers.org/uniprot/Q8N6L6> , <https://identifiers.org/uniprot/P06681> , <https://identifiers.org/uniprot/A0A8Q3WL70> , <https://identifiers.org/uniprot/A0A8Q3WKM9> , <https://identifiers.org/uniprot/A0A8Q3WKM6> , <https://identifiers.org/uniprot/A0A8Q3WKN5> , <https://identifiers.org/uniprot/Q5ST52> , <https://identifiers.org/uniprot/B4DQI1> , <https://identifiers.org/uniprot/F2Z3N2> , <https://identifiers.org/uniprot/E9PDZ0> , <https://identifiers.org/uniprot/H0Y3H6> , <https://identifiers.org/uniprot/F2Z306> , <https://identifiers.org/uniprot/F8WCJ9> , <https://identifiers.org/uniprot/A2ABG0> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5560_r139562/DataNode/cd115> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/B4DQI1> , <http://purl.uniprot.org/uniprot/A0A8Q3WKN5> , <http://purl.uniprot.org/uniprot/P06681> , <http://purl.uniprot.org/uniprot/F2Z306> , <http://purl.uniprot.org/uniprot/C9JYQ5> , <http://purl.uniprot.org/uniprot/H0Y868> , <http://purl.uniprot.org/uniprot/E9PDZ0> , <http://purl.uniprot.org/uniprot/A0A8Q3WKM6> , <http://purl.uniprot.org/uniprot/Q8N6L6> , <http://purl.uniprot.org/uniprot/Q5ST52> , <http://purl.uniprot.org/uniprot/F2Z3N2> , <http://purl.uniprot.org/uniprot/H0Y3H6> , <http://purl.uniprot.org/uniprot/Q5JP69> , <http://purl.uniprot.org/uniprot/A0A8Q3WKM9> , <http://purl.uniprot.org/uniprot/F8WCJ9> , <http://purl.uniprot.org/uniprot/A2ABG0> , <http://purl.uniprot.org/uniprot/A0A8Q3WL70> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000166278> .

<https://identifiers.org/ensembl/ENSG00000114013>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "CD86" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000114013> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000114013" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP5560_r139562> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000114013> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/942> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/CD86> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/P42081> , <https://identifiers.org/uniprot/C9JXS1> , <https://identifiers.org/uniprot/H7C4F8> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q14907527> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5560_r139562/DataNode/d6b56> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/C9JXS1> , <http://purl.uniprot.org/uniprot/H7C4F8> , <http://purl.uniprot.org/uniprot/P42081> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000114013> .

<https://identifiers.org/drugbank/DB15032>
        rdf:type            wp:DataNode , wp:Metabolite ;
        rdfs:label          "Obexelimab" ;
        dc:identifier       <https://identifiers.org/drugbank/DB15032> ;
        dc:source           "DrugBank" ;
        dcterms:identifier  "DB15032" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP5560_r139562> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q123907237> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5560_r139562/DataNode/f0ff7> ;
        foaf:page           <http://www.drugbank.ca/drugs/DB15032> .

<https://identifiers.org/wikipathways/WP5560_r139562>
        rdf:type                skos:Collection , wp:Pathway ;
        dc:identifier           <https://identifiers.org/wikipathways/WP5560> ;
        dc:source               "WikiPathways" ;
        dc:title                "Lupus therapies"@en ;
        dcterms:description     "Therapeutic approaches in systemic lupus erythematosus (SLE) increasingly focus on modulating B and T cell activity.\n\nB cell–directed therapies involve targeting specific surface receptors such as CD19, CD20, CD22, CD38, and CD40, as well as blocking B cell-related cytokines like BAFF (B-cell activating factor, also known as TNFSF13B).  T cell-focused strategies include blocking co-stimulatory pathways (e.g. CD40–CD40L, CD80/86–CD28, ICOS–ICOSL) and inhibiting pro-inflammatory cytokines, including IL-6, IL-12, IL-17, IL-23, and IFN-γ.\n\nInspired by Figure 1 in [Su et al. (2024)](https://pmc.ncbi.nlm.nih.gov/articles/PMC11522254/)." ;
        dcterms:identifier      "WP5560" ;
        dcterms:references      <https://identifiers.org/pubmed/39472388> ;
        cito:cites              <https://identifiers.org/pubmed/39472388> ;
        wp:cellTypeOntologyTag  obo:CL_0000236 , obo:CL_0000451 , obo:CL_1000746 , obo:CL_0000786 , obo:CL_0000084 , obo:CL_0000775 , obo:CL_0000235 ;
        wp:diseaseOntologyTag   obo:DOID_8857 ;
        wp:isAbout              <http://rdf.wikipathways.org/Pathway/WP5560_r139562> ;
        wp:ontologyTag          obo:CL_0000451 , obo:CL_0000786 , obo:CL_0000775 , obo:DOID_8857 , wp:Curation:AnalysisCollection , obo:CL_0000235 , obo:CL_0000084 , obo:PW_0000754 , obo:CL_1000746 , obo:CL_0000236 ;
        wp:organism             obo:NCBITaxon_9606 ;
        wp:organismName         "Homo sapiens" ;
        wp:pathwayOntologyTag   obo:PW_0000754 ;
        foaf:img                <https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=svg&pwTitle=Pathway:WP5560&oldid=139562> , <https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=png&pwTitle=Pathway:WP5560&oldid=139562> ;
        foaf:page               <http://www.wikipathways.org/instance/WP5560_r139562> .

<https://identifiers.org/drugbank/DB16131>
        rdf:type            wp:DataNode , wp:Metabolite ;
        rdfs:label          "Dapirolizumab pegol" ;
        dc:identifier       <https://identifiers.org/drugbank/DB16131> ;
        dc:source           "DrugBank" ;
        dcterms:identifier  "DB16131" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP5560_r139562> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q123906110> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5560_r139562/DataNode/a668d> ;
        foaf:page           <http://www.drugbank.ca/drugs/DB16131> .

<https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=svg&pwTitle=Pathway:WP5560&oldid=139562>
        rdf:type        foaf:Image ;
        dcterms:format  "image/svg+xml" .

<https://identifiers.org/drugbank/DB06650>
        rdf:type            wp:DataNode , wp:Metabolite ;
        rdfs:label          "Ofatumumab" ;
        dc:identifier       <https://identifiers.org/drugbank/DB06650> ;
        dc:source           "DrugBank" ;
        dcterms:identifier  "DB06650" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP5560_r139562> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q410656> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5560_r139562/DataNode/f7c74> ;
        foaf:page           <http://www.drugbank.ca/drugs/DB06650> .

<https://identifiers.org/ensembl/ENSG00000136244>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "IL6" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000136244> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000136244" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP5560_r139562> , <http://rdf.wikipathways.org/Pathway/WP5560_r139562/WP/Interaction/a1fa9> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000136244> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/3569> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/IL6> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/B5MC21> , <https://identifiers.org/uniprot/P05231> , <https://identifiers.org/uniprot/B4DNV3> , <https://identifiers.org/uniprot/C9J5B0> , <https://identifiers.org/uniprot/B5MCZ3> , <https://identifiers.org/uniprot/A0A8Q3SJL1> , <https://identifiers.org/uniprot/Q75MH2> , <https://identifiers.org/uniprot/B5MC14> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q14865236> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5560_r139562/DataNode/cc953> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/B4DNV3> , <http://purl.uniprot.org/uniprot/Q75MH2> , <http://purl.uniprot.org/uniprot/C9J5B0> , <http://purl.uniprot.org/uniprot/B5MC21> , <http://purl.uniprot.org/uniprot/A0A8Q3SJL1> , <http://purl.uniprot.org/uniprot/B5MC14> , <http://purl.uniprot.org/uniprot/B5MCZ3> , <http://purl.uniprot.org/uniprot/P05231> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000136244> .

<https://identifiers.org/ensembl/ENSG00000125730>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "C3" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000125730> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000125730" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP5560_r139562> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000125730> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/718> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/C3> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A8Q3SI05> , <https://identifiers.org/uniprot/V9HWA9> , <https://identifiers.org/uniprot/A0A8Q3SI45> , <https://identifiers.org/uniprot/A0A8Q3SI22> , <https://identifiers.org/uniprot/M0R0Q9> , <https://identifiers.org/uniprot/A0A8Q3WKN7> , <https://identifiers.org/uniprot/P01024> , <https://identifiers.org/uniprot/M0QYC8> , <https://identifiers.org/uniprot/M0QXZ3> , <https://identifiers.org/uniprot/M0R1Q1> , <https://identifiers.org/uniprot/A0A8Q3SI34> , <https://identifiers.org/uniprot/A0A8Q3WM02> , <https://identifiers.org/uniprot/A0A8Q3WLS3> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q14874317> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5560_r139562/DataNode/df53e> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/M0R0Q9> , <http://purl.uniprot.org/uniprot/P01024> , <http://purl.uniprot.org/uniprot/A0A8Q3SI34> , <http://purl.uniprot.org/uniprot/A0A8Q3WM02> , <http://purl.uniprot.org/uniprot/M0QYC8> , <http://purl.uniprot.org/uniprot/A0A8Q3SI22> , <http://purl.uniprot.org/uniprot/A0A8Q3SI45> , <http://purl.uniprot.org/uniprot/A0A8Q3SI05> , <http://purl.uniprot.org/uniprot/V9HWA9> , <http://purl.uniprot.org/uniprot/A0A8Q3WKN7> , <http://purl.uniprot.org/uniprot/A0A8Q3WLS3> , <http://purl.uniprot.org/uniprot/M0R1Q1> , <http://purl.uniprot.org/uniprot/M0QXZ3> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000125730> .

<https://identifiers.org/ensembl/ENSG00000244731>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "C4A" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000244731> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000244731" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP5560_r139562> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000244731> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/720> , <https://identifiers.org/ncbigene/110384692> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/C4A> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/P0C0L4> , <https://identifiers.org/uniprot/A0A8V8TLP6> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q17854107> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5560_r139562/DataNode/b8084> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P0C0L4> , <http://purl.uniprot.org/uniprot/A0A8V8TLP6> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000244731> .

<https://identifiers.org/ensembl/ENSG00000127743>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "IL17B" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000127743> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000127743" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP5560_r139562> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000127743> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/27190> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/IL17B> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q9UHF5> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18038705> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5560_r139562/DataNode/f4ab7> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q9UHF5> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000127743> .

<http://rdf.wikipathways.org/Pathway/WP5560_r139562/WP/Interaction/a1fa9>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP5560_r139562> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP5560_r139562/Interaction/a1fa9> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000136244> , <https://identifiers.org/drugbank/DB14891> ;
        wp:source         <https://identifiers.org/drugbank/DB14891> ;
        wp:target         <https://identifiers.org/ensembl/ENSG00000136244> .

<https://identifiers.org/ensembl/ENSG00000121594>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "CD80" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000121594> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000121594" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP5560_r139562> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000121594> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/941> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/CD80> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0N0P2> , <https://identifiers.org/uniprot/P33681> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q14907505> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5560_r139562/DataNode/c0875> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0N0P2> , <http://purl.uniprot.org/uniprot/P33681> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000121594> .

<https://identifiers.org/drugbank/DB11657>
        rdf:type            wp:Metabolite , wp:DataNode ;
        rdfs:label          "Tabalumab" ;
        dc:identifier       <https://identifiers.org/drugbank/DB11657> ;
        dc:source           "DrugBank" ;
        dcterms:identifier  "DB11657" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP5560_r139562> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q7672878> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5560_r139562/DataNode/a8b21> ;
        foaf:page           <http://www.drugbank.ca/drugs/DB11657> .

<http://rdf.wikipathways.org/Pathway/WP5560_r139562/ComplexBinding/d283d>
        rdf:type          wp:ComplexBinding , wp:Binding , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP5560_r139562> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP5560_r139562/Group/d283d> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000168811> , <https://identifiers.org/ensembl/ENSG00000113302> , <http://rdf.wikipathways.org/Pathway/WP5560_r139562/Complex/d283d> .

<https://identifiers.org/drugbank/DB12530>
        rdf:type            wp:DataNode , wp:Metabolite ;
        rdfs:label          "Inebilizumab" ;
        dc:identifier       <https://identifiers.org/drugbank/DB12530> ;
        dc:source           "DrugBank" ;
        dcterms:identifier  "DB12530" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP5560_r139562> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q25326696> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5560_r139562/DataNode/bf7e9> ;
        foaf:page           <http://www.drugbank.ca/drugs/DB12530> .

<https://identifiers.org/ensembl/ENSG00000159189>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "C1QC" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000159189> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000159189" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP5560_r139562> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000159189> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/714> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/C1QC> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A8Q3SIZ0> , <https://identifiers.org/uniprot/P02747> , <https://identifiers.org/uniprot/A0A8Q3WKR2> , <https://identifiers.org/uniprot/A0A024RAA7> , <https://identifiers.org/uniprot/A0A8Q3WKR6> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q17854035> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5560_r139562/DataNode/d3728> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A8Q3WKR2> , <http://purl.uniprot.org/uniprot/A0A024RAA7> , <http://purl.uniprot.org/uniprot/A0A8Q3WKR6> , <http://purl.uniprot.org/uniprot/P02747> , <http://purl.uniprot.org/uniprot/A0A8Q3SIZ0> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000159189> .

<https://identifiers.org/ensembl/ENSG00000160712>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "IL6R" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000160712> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000160712" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP5560_r139562> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000160712> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/3570> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/IL6R> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/H0Y949> , <https://identifiers.org/uniprot/H0Y9B1> , <https://identifiers.org/uniprot/A0N0L5> , <https://identifiers.org/uniprot/A0A087WTB5> , <https://identifiers.org/uniprot/D6R9R8> , <https://identifiers.org/uniprot/P08887> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18027836> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5560_r139562/DataNode/cb0d8> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0N0L5> , <http://purl.uniprot.org/uniprot/D6R9R8> , <http://purl.uniprot.org/uniprot/A0A087WTB5> , <http://purl.uniprot.org/uniprot/H0Y9B1> , <http://purl.uniprot.org/uniprot/P08887> , <http://purl.uniprot.org/uniprot/H0Y949> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000160712> .

<https://identifiers.org/drugbank/DB08879>
        rdf:type            wp:Metabolite , wp:DataNode ;
        rdfs:label          "Belimumab" ;
        dc:identifier       <https://identifiers.org/drugbank/DB08879> ;
        dc:source           "DrugBank" ;
        dcterms:identifier  "DB08879" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP5560_r139562> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q1996249> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5560_r139562/DataNode/f96fb> ;
        foaf:page           <http://www.drugbank.ca/drugs/DB08879> .

<https://identifiers.org/ensembl/ENSG00000178562>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "CD28" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000178562> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000178562" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP5560_r139562> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000178562> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/940> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/CD28> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/P10747> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q20970073> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5560_r139562/DataNode/ac068> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P10747> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000178562> .

<https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=png&pwTitle=Pathway:WP5560&oldid=139562>
        rdf:type        foaf:Image ;
        dcterms:format  "image/png" .

<https://identifiers.org/drugbank/DB14891>
        rdf:type            wp:DataNode , wp:Metabolite ;
        rdfs:label          "Vobarilizumab" , "Sirukumab" ;
        dc:identifier       <https://identifiers.org/drugbank/DB14891> ;
        dc:source           "DrugBank" ;
        dcterms:identifier  "DB14891" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP5560_r139562> , <http://rdf.wikipathways.org/Pathway/WP5560_r139562/WP/Interaction/a1fa9> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q25326713> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5560_r139562/DataNode/b2d1c> , <http://rdf.wikipathways.org/Pathway/WP5560_r139562/DataNode/cf4f7> ;
        foaf:page           <http://www.drugbank.ca/drugs/DB14891> .

<https://identifiers.org/drugbank/DB16370>
        rdf:type            wp:Metabolite , wp:DataNode ;
        rdfs:label          "Mezagitamab" ;
        dc:identifier       <https://identifiers.org/drugbank/DB16370> ;
        dc:source           "DrugBank" ;
        dcterms:identifier  "DB16370" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP5560_r139562> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5560_r139562/DataNode/af9fa> ;
        foaf:page           <http://www.drugbank.ca/drugs/DB16370> .

<https://identifiers.org/ensembl/ENSG00000102524>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "TNFSF13B" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000102524> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000102524" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP5560_r139562/WP/Interaction/e205a> , <https://identifiers.org/wikipathways/WP5560_r139562> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000102524> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/10673> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/TNFSF13B> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q9Y275> , <https://identifiers.org/uniprot/A0A0U5J7Q1> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q14912856> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5560_r139562/DataNode/c1aed> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q9Y275> , <http://purl.uniprot.org/uniprot/A0A0U5J7Q1> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000102524> .

<https://identifiers.org/ensembl/ENSG00000177455>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "CD19" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000177455> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000177455" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP5560_r139562> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000177455> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/930> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/CD19> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/P15391> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q14907948> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5560_r139562/DataNode/de105> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P15391> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000177455> .

<https://identifiers.org/ensembl/ENSG00000012124>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "CD22" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000012124> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000012124" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP5560_r139562> , <http://rdf.wikipathways.org/Pathway/WP5560_r139562/WP/Interaction/c074a> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000012124> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/933> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/CD22> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/M0QZR7> , <https://identifiers.org/uniprot/M0QYP4> , <https://identifiers.org/uniprot/M0QY14> , <https://identifiers.org/uniprot/A0A087WZQ4> , <https://identifiers.org/uniprot/M0R2M0> , <https://identifiers.org/uniprot/M0QZ01> , <https://identifiers.org/uniprot/M0R0R6> , <https://identifiers.org/uniprot/M0QZP5> , <https://identifiers.org/uniprot/M0QY05> , <https://identifiers.org/uniprot/P20273> , <https://identifiers.org/uniprot/M0R1M2> , <https://identifiers.org/uniprot/M0R2R8> , <https://identifiers.org/uniprot/M0R3H1> , <https://identifiers.org/uniprot/Q0EAF5> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5560_r139562/DataNode/b49f4> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/M0R2R8> , <http://purl.uniprot.org/uniprot/M0QZR7> , <http://purl.uniprot.org/uniprot/A0A087WZQ4> , <http://purl.uniprot.org/uniprot/P20273> , <http://purl.uniprot.org/uniprot/M0QY14> , <http://purl.uniprot.org/uniprot/M0R0R6> , <http://purl.uniprot.org/uniprot/M0R2M0> , <http://purl.uniprot.org/uniprot/Q0EAF5> , <http://purl.uniprot.org/uniprot/M0QZ01> , <http://purl.uniprot.org/uniprot/M0R3H1> , <http://purl.uniprot.org/uniprot/M0QZP5> , <http://purl.uniprot.org/uniprot/M0R1M2> , <http://purl.uniprot.org/uniprot/M0QY05> , <http://purl.uniprot.org/uniprot/M0QYP4> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000012124> .

<https://identifiers.org/ensembl/ENSG00000102245>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "CD40LG" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000102245> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000102245" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP5560_r139562/WP/Interaction/a8d13> , <https://identifiers.org/wikipathways/WP5560_r139562> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000102245> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/959> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/CD40LG> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q3L8U2> , <https://identifiers.org/uniprot/A0A8Q3WKP2> , <https://identifiers.org/uniprot/P29965> , <https://identifiers.org/uniprot/A0A8Q3WL88> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q14897851> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5560_r139562/DataNode/bdc93> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A8Q3WKP2> , <http://purl.uniprot.org/uniprot/P29965> , <http://purl.uniprot.org/uniprot/A0A8Q3WL88> , <http://purl.uniprot.org/uniprot/Q3L8U2> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000102245> .

<https://identifiers.org/ensembl/ENSG00000172458>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "IL17D" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000172458> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000172458" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP5560_r139562> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000172458> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/53342> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/IL17D> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A087WWZ4> , <https://identifiers.org/uniprot/Q8TAD2> , <https://identifiers.org/uniprot/A0A087WW17> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18040608> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5560_r139562/DataNode/f3e3f> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A087WWZ4> , <http://purl.uniprot.org/uniprot/Q8TAD2> , <http://purl.uniprot.org/uniprot/A0A087WW17> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000172458> .

obo:NCBITaxon_9606  obo:NCIT_C179773  "9606" .

<https://identifiers.org/ensembl/ENSG00000173372>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "C1QA" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000173372> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000173372" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP5560_r139562> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000173372> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/712> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/C1QA> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A8Q3SI63> , <https://identifiers.org/uniprot/A0A024RAG6> , <https://identifiers.org/uniprot/A0A8Q3SI59> , <https://identifiers.org/uniprot/P02745> , <https://identifiers.org/uniprot/A0A8Q3SI41> , <https://identifiers.org/uniprot/A0A8Q3SI08> , <https://identifiers.org/uniprot/X6RLJ0> , <https://identifiers.org/uniprot/A0A8Q3SI02> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q17854024> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5560_r139562/DataNode/deccb> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A024RAG6> , <http://purl.uniprot.org/uniprot/P02745> , <http://purl.uniprot.org/uniprot/A0A8Q3SI59> , <http://purl.uniprot.org/uniprot/A0A8Q3SI63> , <http://purl.uniprot.org/uniprot/A0A8Q3SI08> , <http://purl.uniprot.org/uniprot/A0A8Q3SI02> , <http://purl.uniprot.org/uniprot/X6RLJ0> , <http://purl.uniprot.org/uniprot/A0A8Q3SI41> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000173372> .

<http://rdf.wikipathways.org/Pathway/WP5560_r139562/WP/Interaction/c074a>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP5560_r139562> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP5560_r139562/Interaction/c074a> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000012124> , <https://identifiers.org/drugbank/DB04958> ;
        wp:source         <https://identifiers.org/drugbank/DB04958> ;
        wp:target         <https://identifiers.org/ensembl/ENSG00000012124> .

<https://identifiers.org/ensembl/ENSG00000124391>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "IL17C" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000124391> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000124391" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP5560_r139562> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000124391> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/27189> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/IL17C> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q9P0M4> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18038704> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5560_r139562/DataNode/ef084> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q9P0M4> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000124391> .

<https://identifiers.org/drugbank/DB18312>
        rdf:type            wp:DataNode , wp:Metabolite ;
        rdfs:label          "Telitacicept" ;
        dc:identifier       <https://identifiers.org/drugbank/DB18312> ;
        dc:source           "DrugBank" ;
        dcterms:identifier  "DB18312" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP5560_r139562> , <http://rdf.wikipathways.org/Pathway/WP5560_r139562/WP/Interaction/e205a> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5560_r139562/DataNode/fa873> ;
        foaf:page           <http://www.drugbank.ca/drugs/DB18312> .

<http://rdf.wikipathways.org/Pathway/WP5560_r139562/WP/Interaction/a8d13>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP5560_r139562> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP5560_r139562/Interaction/a8d13> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000102245> , <https://identifiers.org/ensembl/ENSG00000101017> ;
        wp:source         <https://identifiers.org/ensembl/ENSG00000101017> ;
        wp:target         <https://identifiers.org/ensembl/ENSG00000102245> .

<https://identifiers.org/drugbank/DB00073>
        rdf:type            wp:Metabolite , wp:DataNode ;
        rdfs:label          "Rituximab" ;
        dc:identifier       <https://identifiers.org/drugbank/DB00073> ;
        dc:source           "DrugBank" ;
        dcterms:identifier  "DB00073" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP5560_r139562> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q412323> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5560_r139562/DataNode/df01c> ;
        foaf:page           <http://www.drugbank.ca/drugs/DB00073> .

<https://identifiers.org/ensembl/ENSG00000168811>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "IL12A" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000168811> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000168811" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP5560_r139562> , <http://rdf.wikipathways.org/Pathway/WP5560_r139562/Complex/d283d> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000168811> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/3592> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/IL12A> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/E9PGR3> , <https://identifiers.org/uniprot/O60595> , <https://identifiers.org/uniprot/P29459> , <https://identifiers.org/uniprot/E7ENE1> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18027869> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5560_r139562/DataNode/b41b9> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/E7ENE1> , <http://purl.uniprot.org/uniprot/E9PGR3> , <http://purl.uniprot.org/uniprot/O60595> , <http://purl.uniprot.org/uniprot/P29459> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000168811> .

<http://rdf.wikipathways.org/Pathway/WP5560_r139562/Complex/a059d>
        rdf:type          wp:Complex , wp:DataNode ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP5560_r139562> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP5560_r139562/Group/a059d> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000110944> , <https://identifiers.org/ensembl/ENSG00000113302> .

<https://identifiers.org/ensembl/ENSG00000111537>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "IFNG" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000111537> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000111537" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP5560_r139562> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000111537> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/3458> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/IFNG> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/P01579> , <https://identifiers.org/uniprot/A0A7R8GUN6> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18027639> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5560_r139562/DataNode/d4be2> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A7R8GUN6> , <http://purl.uniprot.org/uniprot/P01579> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000111537> .

<https://identifiers.org/ensembl/ENSG00000101017>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "CD40" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000101017> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000101017" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP5560_r139562/WP/Interaction/a8d13> , <https://identifiers.org/wikipathways/WP5560_r139562> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000101017> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/958> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/CD40> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/P25942> , <https://identifiers.org/uniprot/A0A0S2Z3C7> , <https://identifiers.org/uniprot/H0YE23> , <https://identifiers.org/uniprot/A0A087X1D0> , <https://identifiers.org/uniprot/A0A8Q3WKP3> , <https://identifiers.org/uniprot/A0A8Q3WKP7> , <https://identifiers.org/uniprot/A0A8Q3SI60> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q17859635> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5560_r139562/DataNode/d7226> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A087X1D0> , <http://purl.uniprot.org/uniprot/A0A8Q3WKP3> , <http://purl.uniprot.org/uniprot/A0A8Q3WKP7> , <http://purl.uniprot.org/uniprot/H0YE23> , <http://purl.uniprot.org/uniprot/P25942> , <http://purl.uniprot.org/uniprot/A0A0S2Z3C7> , <http://purl.uniprot.org/uniprot/A0A8Q3SI60> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000101017> .

<https://identifiers.org/drugbank/DB09331>
        rdf:type            wp:Metabolite , wp:DataNode ;
        rdfs:label          "Daratumumab" ;
        dc:identifier       <https://identifiers.org/drugbank/DB09331> ;
        dc:source           "DrugBank" ;
        dcterms:identifier  "DB09331" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP5560_r139562> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q5222113> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5560_r139562/DataNode/b7e52> ;
        foaf:page           <http://www.drugbank.ca/drugs/DB09331> .

<https://identifiers.org/drugbank/DB11988>
        rdf:type            wp:DataNode , wp:Metabolite ;
        rdfs:label          "Ocrelizumab" ;
        dc:identifier       <https://identifiers.org/drugbank/DB11988> ;
        dc:source           "DrugBank" ;
        dcterms:identifier  "DB11988" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP5560_r139562> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q2013780> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5560_r139562/DataNode/a0056> ;
        foaf:page           <http://www.drugbank.ca/drugs/DB11988> .

<https://identifiers.org/drugbank/DB11834>
        rdf:type            wp:Metabolite , wp:DataNode ;
        rdfs:label          "Guselkumab" ;
        dc:identifier       <https://identifiers.org/drugbank/DB11834> ;
        dc:source           "DrugBank" ;
        dcterms:identifier  "DB11834" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP5560_r139562> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q15708315> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5560_r139562/DataNode/d8cef> ;
        foaf:page           <http://www.drugbank.ca/drugs/DB11834> .

<https://identifiers.org/ensembl/ENSG00000166090>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "IL25" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000166090> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000166090" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP5560_r139562> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000166090> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/64806> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/IL25> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q9H293> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q14907251> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5560_r139562/DataNode/f5dfe> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q9H293> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000166090> .

<https://identifiers.org/wikidata/Q785022>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "Autoantibodies" ;
        dc:identifier       <https://identifiers.org/wikidata/Q785022> ;
        dc:source           "Wikidata" ;
        dcterms:identifier  "Q785022" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP5560_r139562> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q785022> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5560_r139562/DataNode/c1843> ;
        foaf:page           <https://scholia.toolforge.org/Q785022> .

<https://identifiers.org/ensembl/ENSG00000110944>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "IL23A" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000110944> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000110944" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP5560_r139562> , <http://rdf.wikipathways.org/Pathway/WP5560_r139562/Complex/a059d> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000110944> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/51561> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/IL23A> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q9NPF7> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18040395> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5560_r139562/DataNode/cf751> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q9NPF7> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000110944> .

<https://identifiers.org/drugbank/DB16666>
        rdf:type            wp:DataNode , wp:Metabolite ;
        rdfs:label          "Ianalumab" ;
        dc:identifier       <https://identifiers.org/drugbank/DB16666> ;
        dc:source           "DrugBank" ;
        dcterms:identifier  "DB16666" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP5560_r139562> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5560_r139562/DataNode/c5d73> , <http://rdf.wikipathways.org/Pathway/WP5560_r139562/DataNode/bb464> ;
        foaf:page           <http://www.drugbank.ca/drugs/DB16666> .

<https://identifiers.org/ensembl/ENSG00000113302>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "IL12B" , "IL23B" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000113302> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000113302" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP5560_r139562> , <http://rdf.wikipathways.org/Pathway/WP5560_r139562/Complex/a059d> , <http://rdf.wikipathways.org/Pathway/WP5560_r139562/Complex/d283d> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000113302> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/3593> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/IL12B> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/P29460> , <https://identifiers.org/uniprot/A0A8Q3SJ12> , <https://identifiers.org/uniprot/A0A8Q3WML5> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18027872> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5560_r139562/DataNode/ea5a6> , <http://rdf.wikipathways.org/Pathway/WP5560_r139562/DataNode/e9b83> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P29460> , <http://purl.uniprot.org/uniprot/A0A8Q3WML5> , <http://purl.uniprot.org/uniprot/A0A8Q3SJ12> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000113302> .

<https://identifiers.org/ensembl/ENSG00000173369>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "C1QB" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000173369> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000173369" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP5560_r139562> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000173369> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/713> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/C1QB> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A8Q3SI50> , <https://identifiers.org/uniprot/A0A8Q3WM25> , <https://identifiers.org/uniprot/D6RGJ1> , <https://identifiers.org/uniprot/A0A0A0MSV6> , <https://identifiers.org/uniprot/D6R934> , <https://identifiers.org/uniprot/A0A8Q3SI33> , <https://identifiers.org/uniprot/A0A8Q3SI72> , <https://identifiers.org/uniprot/A0A8Q3WKR5> , <https://identifiers.org/uniprot/A0A8Q3WLT6> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q17854030> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5560_r139562/DataNode/a3a34> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A8Q3SI33> , <http://purl.uniprot.org/uniprot/A0A8Q3SI72> , <http://purl.uniprot.org/uniprot/A0A8Q3SI50> , <http://purl.uniprot.org/uniprot/A0A0A0MSV6> , <http://purl.uniprot.org/uniprot/D6R934> , <http://purl.uniprot.org/uniprot/A0A8Q3WLT6> , <http://purl.uniprot.org/uniprot/A0A8Q3WKR5> , <http://purl.uniprot.org/uniprot/D6RGJ1> , <http://purl.uniprot.org/uniprot/A0A8Q3WM25> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000173369> .

<https://identifiers.org/ensembl/ENSG00000112116>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "IL17F" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000112116> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000112116" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP5560_r139562> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000112116> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/112744> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/IL17F> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q96PD4> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18048865> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5560_r139562/DataNode/d6cc7> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q96PD4> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000112116> .

<https://identifiers.org/drugbank/DB05679>
        rdf:type            wp:Metabolite , wp:DataNode ;
        rdfs:label          "Ustekinumab" ;
        dc:identifier       <https://identifiers.org/drugbank/DB05679> ;
        dc:source           "DrugBank" ;
        dcterms:identifier  "DB05679" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP5560_r139562> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q420305> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5560_r139562/DataNode/ff089> ;
        foaf:page           <http://www.drugbank.ca/drugs/DB05679> .

<https://identifiers.org/ensembl/ENSG00000004468>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "CD38" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000004468> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000004468" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP5560_r139562> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000004468> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/952> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/CD38> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/H0Y950> , <https://identifiers.org/uniprot/P28907> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q14885119> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5560_r139562/DataNode/c3097> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P28907> , <http://purl.uniprot.org/uniprot/H0Y950> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000004468> .

<https://identifiers.org/ensembl/ENSG00000224389>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "C4B" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000224389> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000224389" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP5560_r139562> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000224389> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/721> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/C4B> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A3B3ISD7> , <https://identifiers.org/uniprot/A0A3B3ISA6> , <https://identifiers.org/uniprot/F5GXS0> , <https://identifiers.org/uniprot/P0C0L5> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5560_r139562/DataNode/bf55c> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P0C0L5> , <http://purl.uniprot.org/uniprot/A0A3B3ISA6> , <http://purl.uniprot.org/uniprot/F5GXS0> , <http://purl.uniprot.org/uniprot/A0A3B3ISD7> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000224389> .

<https://identifiers.org/drugbank/DB09029>
        rdf:type            wp:DataNode , wp:Metabolite ;
        rdfs:label          "Secukinumab" ;
        dc:identifier       <https://identifiers.org/drugbank/DB09029> ;
        dc:source           "DrugBank" ;
        dcterms:identifier  "DB09029" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP5560_r139562> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q7444755> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5560_r139562/DataNode/badd6> ;
        foaf:page           <http://www.drugbank.ca/drugs/DB09029> .

<https://identifiers.org/drugbank/DB08935>
        rdf:type            wp:Metabolite , wp:DataNode ;
        rdfs:label          "Obinutuzumab" ;
        dc:identifier       <https://identifiers.org/drugbank/DB08935> ;
        dc:source           "DrugBank" ;
        dcterms:identifier  "DB08935" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP5560_r139562> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q389496> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5560_r139562/DataNode/a2534> ;
        foaf:page           <http://www.drugbank.ca/drugs/DB08935> .

<https://identifiers.org/drugbank/DB04958>
        rdf:type            wp:DataNode , wp:Metabolite ;
        rdfs:label          "Epratuzumab" ;
        dc:identifier       <https://identifiers.org/drugbank/DB04958> ;
        dc:source           "DrugBank" ;
        dcterms:identifier  "DB04958" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP5560_r139562> , <http://rdf.wikipathways.org/Pathway/WP5560_r139562/WP/Interaction/c074a> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q3730737> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5560_r139562/DataNode/c034d> ;
        foaf:page           <http://www.drugbank.ca/drugs/DB04958> .

<https://identifiers.org/drugbank/DB06273>
        rdf:type            wp:Metabolite , wp:DataNode ;
        rdfs:label          "Tocilizumab" ;
        dc:identifier       <https://identifiers.org/drugbank/DB06273> ;
        dc:source           "DrugBank" ;
        dcterms:identifier  "DB06273" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP5560_r139562> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q425154> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5560_r139562/DataNode/de466> ;
        foaf:page           <http://www.drugbank.ca/drugs/DB06273> .

<https://identifiers.org/drugbank/DB06399>
        rdf:type            wp:DataNode , wp:Metabolite ;
        rdfs:label          "Atacicept" ;
        dc:identifier       <https://identifiers.org/drugbank/DB06399> ;
        dc:source           "DrugBank" ;
        dcterms:identifier  "DB06399" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP5560_r139562> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q426122> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5560_r139562/DataNode/ec834> ;
        foaf:page           <http://www.drugbank.ca/drugs/DB06399> .

<https://identifiers.org/pubmed/39472388>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "39472388" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP5560_r139562> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/39472388> .

<https://identifiers.org/wikipathways/WP5560>
        pav:hasVersion  <https://identifiers.org/wikipathways/WP5560_r139562> .

<https://identifiers.org/ensembl/ENSG00000156738>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "MS4A1" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000156738> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000156738" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP5560_r139562> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000156738> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/931> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/MS4A1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/E9PKH8> , <https://identifiers.org/uniprot/A0A024R507> , <https://identifiers.org/uniprot/P11836> , <https://identifiers.org/uniprot/E9PPL6> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q14906101> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5560_r139562/DataNode/e932f> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P11836> , <http://purl.uniprot.org/uniprot/E9PPL6> , <http://purl.uniprot.org/uniprot/A0A024R507> , <http://purl.uniprot.org/uniprot/E9PKH8> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000156738> .

<https://identifiers.org/ensembl/ENSG00000112115>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "IL17A" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000112115> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000112115" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP5560_r139562> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000112115> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/3605> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/IL17A> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q16552> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18027889> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5560_r139562/DataNode/f4b8b> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q16552> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000112115> .

<http://rdf.wikipathways.org/Pathway/WP5560_r139562/ComplexBinding/a059d>
        rdf:type          wp:ComplexBinding , wp:Binding , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP5560_r139562> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP5560_r139562/Group/a059d> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000110944> , <https://identifiers.org/ensembl/ENSG00000113302> , <http://rdf.wikipathways.org/Pathway/WP5560_r139562/Complex/a059d> .

<http://rdf.wikipathways.org/Pathway/WP5560_r139562/Complex/d283d>
        rdf:type          wp:Complex , wp:DataNode ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP5560_r139562> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP5560_r139562/Group/d283d> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000168811> , <https://identifiers.org/ensembl/ENSG00000113302> .

<http://rdf.wikipathways.org/Pathway/WP5560_r139562/WP/Interaction/e205a>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP5560_r139562> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP5560_r139562/Interaction/e205a> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000102524> , <https://identifiers.org/drugbank/DB18312> ;
        wp:source         <https://identifiers.org/drugbank/DB18312> ;
        wp:target         <https://identifiers.org/ensembl/ENSG00000102524> .
