@prefix biopax:  <http://www.biopax.org/release/biopax-level3.owl#> .
@prefix cito:    <http://purl.org/spar/cito/> .
@prefix dc:      <http://purl.org/dc/elements/1.1/> .
@prefix dcterms: <http://purl.org/dc/terms/> .
@prefix foaf:    <http://xmlns.com/foaf/0.1/> .
@prefix freq:    <http://purl.org/cld/freq/> .
@prefix gpml:    <http://vocabularies.wikipathways.org/gpml#> .
@prefix obo:     <http://purl.obolibrary.org/obo/> .
@prefix owl:     <http://www.w3.org/2002/07/owl#> .
@prefix pav:     <http://purl.org/pav/> .
@prefix prov:    <http://www.w3.org/ns/prov#> .
@prefix rdf:     <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix rdfs:    <http://www.w3.org/2000/01/rdf-schema#> .
@prefix skos:    <http://www.w3.org/2004/02/skos/core#> .
@prefix void:    <http://rdfs.org/ns/void#> .
@prefix wp:      <http://vocabularies.wikipathways.org/wp#> .
@prefix wprdf:   <http://rdf.wikipathways.org/> .
@prefix xsd:     <http://www.w3.org/2001/XMLSchema#> .

<http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/d3a84>
        rdf:type          wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP286_r142061> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP286_r142061/Interaction/d3a84> .

<http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/f178e>
        rdf:type          wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP286_r142061> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP286_r142061/Interaction/f178e> ;
        wp:participants   <https://identifiers.org/ncbigene/3563> .

<https://identifiers.org/ncbigene/9846>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "GAB2" ;
        dc:identifier       <https://identifiers.org/ncbigene/9846> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "9846" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/idf19f16de> , <https://identifiers.org/wikipathways/WP286_r142061> , <http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/id6825bb72> , <http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/id147d1aac> , <http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/d85c0> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000033327> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/9846> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/GAB2> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q9UQC2> , <https://identifiers.org/uniprot/E9PJE2> , <https://identifiers.org/uniprot/E9PJ26> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP286_r142061/DataNode/b6043> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/E9PJ26> , <http://purl.uniprot.org/uniprot/E9PJE2> , <http://purl.uniprot.org/uniprot/Q9UQC2> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/9846> .

<https://identifiers.org/ncbigene/1232>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "CCR3" ;
        dc:identifier       <https://identifiers.org/ncbigene/1232> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "1232" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP286_r142061> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000183625> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/1232> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/CCR3> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A1LPE5> , <https://identifiers.org/uniprot/Q8TDP5> , <https://identifiers.org/uniprot/Q8TDP4> , <https://identifiers.org/uniprot/P51677> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP286_r142061/DataNode/bb81d> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q8TDP5> , <http://purl.uniprot.org/uniprot/A1LPE5> , <http://purl.uniprot.org/uniprot/P51677> , <http://purl.uniprot.org/uniprot/Q8TDP4> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/1232> .

<https://identifiers.org/ncbigene/5169>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "ENPP3" ;
        dc:identifier       <https://identifiers.org/ncbigene/5169> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "5169" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP286_r142061> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000154269> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/5169> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/ENPP3> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/E7ETI7> , <https://identifiers.org/uniprot/F8W6H5> , <https://identifiers.org/uniprot/O14638> , <https://identifiers.org/uniprot/E9PDB4> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP286_r142061/DataNode/ac7cb> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/E9PDB4> , <http://purl.uniprot.org/uniprot/F8W6H5> , <http://purl.uniprot.org/uniprot/E7ETI7> , <http://purl.uniprot.org/uniprot/O14638> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/5169> .

<https://identifiers.org/ncbigene/1399>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "CRKL" ;
        dc:identifier       <https://identifiers.org/ncbigene/1399> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "1399" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP286_r142061> , <http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/id2b48d3a4> , <http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/ee904> , <http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/idcc4a2fb3> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000099942> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/1399> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/CRKL> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/P46109> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP286_r142061/DataNode/f88e6> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P46109> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/1399> .

<http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/d42f8>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP286_r142061> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP286_r142061/Interaction/d42f8> ;
        wp:participants   <https://identifiers.org/ncbigene/5894> , <https://identifiers.org/ncbigene/3265> ;
        wp:source         <https://identifiers.org/ncbigene/3265> ;
        wp:target         <https://identifiers.org/ncbigene/5894> .

<http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/e9d5e>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP286_r142061> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP286_r142061/Interaction/e9d5e> ;
        wp:participants   <https://identifiers.org/ncbigene/3716> , <https://identifiers.org/ncbigene/3563> ;
        wp:source         <https://identifiers.org/ncbigene/3563> ;
        wp:target         <https://identifiers.org/ncbigene/3716> .

<http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/c8b65>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP286_r142061> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP286_r142061/Interaction/c8b65> ;
        wp:participants   <https://identifiers.org/ncbigene/6774> , <https://identifiers.org/ncbigene/6714> ;
        wp:source         <https://identifiers.org/ncbigene/6714> ;
        wp:target         <https://identifiers.org/ncbigene/6774> .

<https://identifiers.org/ncbigene/6654>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "SOS1" ;
        dc:identifier       <https://identifiers.org/ncbigene/6654> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "6654" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/id925298d1> , <http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/b32e9> , <https://identifiers.org/wikipathways/WP286_r142061> , <http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/d3e2c> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000115904> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/6654> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/SOS1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A8I5QJF3> , <https://identifiers.org/uniprot/A0A8I5QJ77> , <https://identifiers.org/uniprot/A0A8I5KP47> , <https://identifiers.org/uniprot/C9K0N6> , <https://identifiers.org/uniprot/A0A8I5KWL0> , <https://identifiers.org/uniprot/G5E9C8> , <https://identifiers.org/uniprot/A0A8I5KY52> , <https://identifiers.org/uniprot/A0A8I5KV97> , <https://identifiers.org/uniprot/Q07889> , <https://identifiers.org/uniprot/A0A8I5QJD1> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP286_r142061/DataNode/cd169> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A8I5KP47> , <http://purl.uniprot.org/uniprot/A0A8I5KWL0> , <http://purl.uniprot.org/uniprot/A0A8I5QJD1> , <http://purl.uniprot.org/uniprot/G5E9C8> , <http://purl.uniprot.org/uniprot/A0A8I5QJ77> , <http://purl.uniprot.org/uniprot/A0A8I5QJF3> , <http://purl.uniprot.org/uniprot/Q07889> , <http://purl.uniprot.org/uniprot/C9K0N6> , <http://purl.uniprot.org/uniprot/A0A8I5KY52> , <http://purl.uniprot.org/uniprot/A0A8I5KV97> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/6654> .

<https://identifiers.org/ncbigene/596>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "BCL2" ;
        dc:identifier       <https://identifiers.org/ncbigene/596> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "596" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/idf11455c2> , <https://identifiers.org/wikipathways/WP286_r142061> , <http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/ba3bc> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000171791> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/596> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/BCL2> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A7I2V5Q7> , <https://identifiers.org/uniprot/A0A7I2V4W1> , <https://identifiers.org/uniprot/P10415> , <https://identifiers.org/uniprot/A0A024R2C4> , <https://identifiers.org/uniprot/A0A7I2V5Q9> , <https://identifiers.org/uniprot/A0A024R2B3> , <https://identifiers.org/uniprot/A0A7I2V3S7> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP286_r142061/DataNode/afe89> , <http://rdf.wikipathways.org/Pathway/WP286_r142061/DataNode/b2359> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A7I2V3S7> , <http://purl.uniprot.org/uniprot/A0A7I2V5Q9> , <http://purl.uniprot.org/uniprot/A0A024R2C4> , <http://purl.uniprot.org/uniprot/A0A7I2V4W1> , <http://purl.uniprot.org/uniprot/A0A7I2V5Q7> , <http://purl.uniprot.org/uniprot/A0A024R2B3> , <http://purl.uniprot.org/uniprot/P10415> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/596> .

<https://identifiers.org/ncbigene/207>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "AKT1" ;
        dc:identifier       <https://identifiers.org/ncbigene/207> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "207" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/b8f66> , <http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/idf11455c2> , <http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/idbdf5c425> , <http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/bbd5b> , <https://identifiers.org/wikipathways/WP286_r142061> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000142208> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/207> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/AKT1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/P31749> , <https://identifiers.org/uniprot/A0A804HJM6> , <https://identifiers.org/uniprot/B0LPE5> , <https://identifiers.org/uniprot/G3V2I6> , <https://identifiers.org/uniprot/A0A087WY56> , <https://identifiers.org/uniprot/G3V3X1> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP286_r142061/DataNode/cb5e5> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/G3V2I6> , <http://purl.uniprot.org/uniprot/B0LPE5> , <http://purl.uniprot.org/uniprot/A0A804HJM6> , <http://purl.uniprot.org/uniprot/A0A087WY56> , <http://purl.uniprot.org/uniprot/P31749> , <http://purl.uniprot.org/uniprot/G3V3X1> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/207> .

<http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/idd26c2313>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP286_r142061> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP286_r142061/Interaction/idd26c2313> ;
        wp:participants   <https://identifiers.org/ncbigene/5295> , <https://identifiers.org/ncbigene/867> ;
        wp:source         <https://identifiers.org/ncbigene/867> ;
        wp:target         <https://identifiers.org/ncbigene/5295> .

<http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/ad3ab>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP286_r142061> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP286_r142061/Interaction/ad3ab> ;
        wp:participants   <https://identifiers.org/ncbigene/3725> , <https://identifiers.org/ncbigene/5595> ;
        wp:source         <https://identifiers.org/ncbigene/5595> ;
        wp:target         <https://identifiers.org/ncbigene/3725> .

<http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/idc13ff83>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP286_r142061> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP286_r142061/Interaction/idc13ff83> ;
        wp:participants   <https://identifiers.org/ncbigene/5594> , <https://identifiers.org/ncbigene/5604> ;
        wp:source         <https://identifiers.org/ncbigene/5604> ;
        wp:target         <https://identifiers.org/ncbigene/5594> .

<http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/id7307129b>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP286_r142061> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP286_r142061/Interaction/id7307129b> ;
        wp:participants   <https://identifiers.org/ncbigene/6776> , <https://identifiers.org/ncbigene/5781> ;
        wp:source         <https://identifiers.org/ncbigene/5781> ;
        wp:target         <https://identifiers.org/ncbigene/6776> .

<http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/ee904>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP286_r142061> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP286_r142061/Interaction/ee904> ;
        wp:participants   <https://identifiers.org/ncbigene/867> , <https://identifiers.org/ncbigene/1399> ;
        wp:source         <https://identifiers.org/ncbigene/1399> ;
        wp:target         <https://identifiers.org/ncbigene/867> .

<http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/ced91>
        rdf:type          wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP286_r142061> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP286_r142061/Interaction/ced91> ;
        wp:participants   <https://identifiers.org/ncbigene/3562> .

<https://identifiers.org/ncbigene/6774>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "STAT3" ;
        dc:identifier       <https://identifiers.org/ncbigene/6774> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "6774" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/ee3a8> , <http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/c8b65> , <https://identifiers.org/wikipathways/WP286_r142061> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000168610> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/6774> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/STAT3> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A7I2V4F6> , <https://identifiers.org/uniprot/A0A7I2YQI1> , <https://identifiers.org/uniprot/A0A7I2V2T1> , <https://identifiers.org/uniprot/A0A7I2V3V0> , <https://identifiers.org/uniprot/A0A7I2V4R2> , <https://identifiers.org/uniprot/A0A7I2V395> , <https://identifiers.org/uniprot/A0A7I2V5N9> , <https://identifiers.org/uniprot/P40763> , <https://identifiers.org/uniprot/A0A7I2V444> , <https://identifiers.org/uniprot/A0A7I2V4C8> , <https://identifiers.org/uniprot/A0A7I2V4R3> , <https://identifiers.org/uniprot/A0A7I2V552> , <https://identifiers.org/uniprot/A0A7I2YQR5> , <https://identifiers.org/uniprot/A0A7I2V2G1> , <https://identifiers.org/uniprot/G8JLH9> , <https://identifiers.org/uniprot/A0A7I2YQD2> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP286_r142061/DataNode/b903f> , <http://rdf.wikipathways.org/Pathway/WP286_r142061/DataNode/ea24f> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A7I2YQI1> , <http://purl.uniprot.org/uniprot/P40763> , <http://purl.uniprot.org/uniprot/A0A7I2V5N9> , <http://purl.uniprot.org/uniprot/G8JLH9> , <http://purl.uniprot.org/uniprot/A0A7I2V4R3> , <http://purl.uniprot.org/uniprot/A0A7I2V3V0> , <http://purl.uniprot.org/uniprot/A0A7I2V4F6> , <http://purl.uniprot.org/uniprot/A0A7I2V444> , <http://purl.uniprot.org/uniprot/A0A7I2V395> , <http://purl.uniprot.org/uniprot/A0A7I2V2T1> , <http://purl.uniprot.org/uniprot/A0A7I2V4R2> , <http://purl.uniprot.org/uniprot/A0A7I2YQR5> , <http://purl.uniprot.org/uniprot/A0A7I2V552> , <http://purl.uniprot.org/uniprot/A0A7I2V4C8> , <http://purl.uniprot.org/uniprot/A0A7I2V2G1> , <http://purl.uniprot.org/uniprot/A0A7I2YQD2> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/6774> .

<https://identifiers.org/ncbigene/3635>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "INPP5D" ;
        dc:identifier       <https://identifiers.org/ncbigene/3635> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "3635" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP286_r142061> , <http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/idcc4a2fb3> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000168918> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/3635> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/INPP5D> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/H7C403> , <https://identifiers.org/uniprot/R4GMN8> , <https://identifiers.org/uniprot/Q92835> , <https://identifiers.org/uniprot/H0Y5Q9> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP286_r142061/DataNode/e8c00> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/R4GMN8> , <http://purl.uniprot.org/uniprot/H7C403> , <http://purl.uniprot.org/uniprot/H0Y5Q9> , <http://purl.uniprot.org/uniprot/Q92835> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/3635> .

<https://identifiers.org/ncbigene/867>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "CBL" ;
        dc:identifier       <https://identifiers.org/ncbigene/867> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "867" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/idd26c2313> , <http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/c9ff4> , <https://identifiers.org/wikipathways/WP286_r142061> , <http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/ee904> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000110395> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/867> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/CBL> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A0U1RRJ5> , <https://identifiers.org/uniprot/P22681> , <https://identifiers.org/uniprot/A0A8V8TQA9> , <https://identifiers.org/uniprot/A0A1B0GW38> , <https://identifiers.org/uniprot/A0A0U1RQX8> , <https://identifiers.org/uniprot/A0A0U1RR39> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP286_r142061/DataNode/a4d05> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A0U1RRJ5> , <http://purl.uniprot.org/uniprot/A0A1B0GW38> , <http://purl.uniprot.org/uniprot/A0A8V8TQA9> , <http://purl.uniprot.org/uniprot/A0A0U1RQX8> , <http://purl.uniprot.org/uniprot/A0A0U1RR39> , <http://purl.uniprot.org/uniprot/P22681> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/867> .

<https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=png&pwTitle=Pathway:WP286&oldid=142061>
        rdf:type        foaf:Image ;
        dcterms:format  "image/png" .

<https://identifiers.org/ncbigene/3563>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "IL3RA" ;
        dc:identifier       <https://identifiers.org/ncbigene/3563> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "3563" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/e9d5e> , <https://identifiers.org/wikipathways/WP286_r142061> , <http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/f178e> , <http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/ide95b63c5> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000292332> , <https://identifiers.org/ensembl/ENSG00000185291> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/3563> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/IL3RA> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/J3JS34> , <https://identifiers.org/uniprot/P26951> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP286_r142061/DataNode/ab432> , <http://rdf.wikipathways.org/Pathway/WP286_r142061/DataNode/d97eb> , <http://rdf.wikipathways.org/Pathway/WP286_r142061/DataNode/a1480> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P26951> , <http://purl.uniprot.org/uniprot/J3JS34> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/3563> .

<https://identifiers.org/ncbigene/5296>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "PIK3R2" ;
        dc:identifier       <https://identifiers.org/ncbigene/5296> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "5296" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/idbdf5c425> , <https://identifiers.org/wikipathways/WP286_r142061> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000105647> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/5296> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/PIK3R2> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/V9GYJ4> , <https://identifiers.org/uniprot/A0A7I2U3A3> , <https://identifiers.org/uniprot/O00459> , <https://identifiers.org/uniprot/A0A087X257> , <https://identifiers.org/uniprot/E9PFP1> , <https://identifiers.org/uniprot/A0A5F9ZHY3> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP286_r142061/DataNode/f92cd> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A5F9ZHY3> , <http://purl.uniprot.org/uniprot/A0A7I2U3A3> , <http://purl.uniprot.org/uniprot/O00459> , <http://purl.uniprot.org/uniprot/V9GYJ4> , <http://purl.uniprot.org/uniprot/E9PFP1> , <http://purl.uniprot.org/uniprot/A0A087X257> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/5296> .

<https://identifiers.org/pmc/PMC7339012>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed Central" ;
        dcterms:identifier  "PMC7339012" ;
        cito:cites          <https://identifiers.org/wikipathways/WP286> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/PMC7339012> .

<https://identifiers.org/ncbigene/3576>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "IL8" ;
        dc:identifier       <https://identifiers.org/ncbigene/3576> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "3576" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP286_r142061> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000169429> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/3576> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/CXCL8> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A8Q3SIG6> , <https://identifiers.org/uniprot/P10145> , <https://identifiers.org/uniprot/A0A024RDA5> , <https://identifiers.org/uniprot/C9J4T6> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP286_r142061/DataNode/d5545> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/C9J4T6> , <http://purl.uniprot.org/uniprot/P10145> , <http://purl.uniprot.org/uniprot/A0A024RDA5> , <http://purl.uniprot.org/uniprot/A0A8Q3SIG6> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/3576> .

<https://identifiers.org/pubmed/20067622>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "20067622" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP286_r142061> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/20067622> .

<https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=svg&pwTitle=Pathway:WP286&oldid=142061>
        rdf:type        foaf:Image ;
        dcterms:format  "image/svg+xml" .

<https://identifiers.org/ncbigene/2889>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "RAPGEF1" ;
        dc:identifier       <https://identifiers.org/ncbigene/2889> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "2889" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/id2b48d3a4> , <https://identifiers.org/wikipathways/WP286_r142061> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000107263> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/2889> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/RAPGEF1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/H0Y6R4> , <https://identifiers.org/uniprot/A0A804HL87> , <https://identifiers.org/uniprot/Q5JUE9> , <https://identifiers.org/uniprot/Q13905> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP286_r142061/DataNode/e68fc> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q13905> , <http://purl.uniprot.org/uniprot/H0Y6R4> , <http://purl.uniprot.org/uniprot/A0A804HL87> , <http://purl.uniprot.org/uniprot/Q5JUE9> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/2889> .

<https://identifiers.org/ncbigene/5595>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "MAPK3" ;
        dc:identifier       <https://identifiers.org/ncbigene/5595> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "5595" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/ad3ab> , <http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/a0d99> , <http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/f3dae> , <https://identifiers.org/wikipathways/WP286_r142061> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000102882> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/5595> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/MAPK3> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/E9PQW4> , <https://identifiers.org/uniprot/H0YDH9> , <https://identifiers.org/uniprot/H0YEX6> , <https://identifiers.org/uniprot/B3KR49> , <https://identifiers.org/uniprot/E9PRH7> , <https://identifiers.org/uniprot/L7RXH5> , <https://identifiers.org/uniprot/E9PJF0> , <https://identifiers.org/uniprot/E9PBK7> , <https://identifiers.org/uniprot/P27361> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP286_r142061/DataNode/d3c8c> , <http://rdf.wikipathways.org/Pathway/WP286_r142061/DataNode/e291b> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/E9PBK7> , <http://purl.uniprot.org/uniprot/B3KR49> , <http://purl.uniprot.org/uniprot/L7RXH5> , <http://purl.uniprot.org/uniprot/H0YDH9> , <http://purl.uniprot.org/uniprot/E9PJF0> , <http://purl.uniprot.org/uniprot/E9PQW4> , <http://purl.uniprot.org/uniprot/P27361> , <http://purl.uniprot.org/uniprot/H0YEX6> , <http://purl.uniprot.org/uniprot/E9PRH7> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/5595> .

<http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/id2b48d3a4>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP286_r142061> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP286_r142061/Interaction/id2b48d3a4> ;
        wp:participants   <https://identifiers.org/ncbigene/2889> , <https://identifiers.org/ncbigene/1399> ;
        wp:source         <https://identifiers.org/ncbigene/1399> ;
        wp:target         <https://identifiers.org/ncbigene/2889> .

<https://doi.org/10.1016%2Fj.compbiomed.2014.12.003>
        rdf:type            wp:PublicationReference ;
        dc:source           "DOI" ;
        dcterms:identifier  "10.1016/j.compbiomed.2014.12.003" ;
        cito:cites          <https://identifiers.org/wikipathways/WP286> .

<http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/ide95b63c5>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP286_r142061> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP286_r142061/Interaction/ide95b63c5> ;
        wp:participants   <https://identifiers.org/ncbigene/3717> , <https://identifiers.org/ncbigene/3563> ;
        wp:source         <https://identifiers.org/ncbigene/3563> ;
        wp:target         <https://identifiers.org/ncbigene/3717> .

<http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/c9ff4>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP286_r142061> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP286_r142061/Interaction/c9ff4> ;
        wp:participants   <https://identifiers.org/ncbigene/867> , <https://identifiers.org/ncbigene/2534> ;
        wp:source         <https://identifiers.org/ncbigene/2534> ;
        wp:target         <https://identifiers.org/ncbigene/867> .

<http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/d85c0>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP286_r142061> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP286_r142061/Interaction/d85c0> ;
        wp:participants   <https://identifiers.org/ncbigene/9846> , <https://identifiers.org/ncbigene/6464> ;
        wp:source         <https://identifiers.org/ncbigene/6464> ;
        wp:target         <https://identifiers.org/ncbigene/9846> .

<http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/b32e9>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP286_r142061> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP286_r142061/Interaction/b32e9> ;
        wp:participants   <https://identifiers.org/ncbigene/3265> , <https://identifiers.org/ncbigene/6654> ;
        wp:source         <https://identifiers.org/ncbigene/6654> ;
        wp:target         <https://identifiers.org/ncbigene/3265> .

<https://identifiers.org/ncbigene/3568>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "IL5RA" ;
        dc:identifier       <https://identifiers.org/ncbigene/3568> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "3568" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP286_r142061> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000091181> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/3568> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/IL5RA> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/E7ERY4> , <https://identifiers.org/uniprot/C9J3K8> , <https://identifiers.org/uniprot/C9J6C4> , <https://identifiers.org/uniprot/Q01344> , <https://identifiers.org/uniprot/A0A024R2E8> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP286_r142061/DataNode/a71ec> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/C9J3K8> , <http://purl.uniprot.org/uniprot/E7ERY4> , <http://purl.uniprot.org/uniprot/C9J6C4> , <http://purl.uniprot.org/uniprot/A0A024R2E8> , <http://purl.uniprot.org/uniprot/Q01344> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/3568> .

<https://identifiers.org/ncbigene/5894>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "RAF1" ;
        dc:identifier       <https://identifiers.org/ncbigene/5894> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "5894" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP286_r142061> , <http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/d42f8> , <http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/idd4e467bf> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000132155> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/5894> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/RAF1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A8I5KS16> , <https://identifiers.org/uniprot/A0A0S2Z559> , <https://identifiers.org/uniprot/A0A8I5KWA9> , <https://identifiers.org/uniprot/A0A8I5KSV6> , <https://identifiers.org/uniprot/A0A8I5KQV4> , <https://identifiers.org/uniprot/A0A8I5KSB0> , <https://identifiers.org/uniprot/A0A8I5KYP5> , <https://identifiers.org/uniprot/A0A8I5KTK4> , <https://identifiers.org/uniprot/A0A8I5KSM4> , <https://identifiers.org/uniprot/P04049> , <https://identifiers.org/uniprot/A0A8I5KT32> , <https://identifiers.org/uniprot/A0A0B4J1W9> , <https://identifiers.org/uniprot/A0A8I5QKU8> , <https://identifiers.org/uniprot/A0A8I5KWS9> , <https://identifiers.org/uniprot/A0A8I5KUW4> , <https://identifiers.org/uniprot/A0A8I5KQ33> , <https://identifiers.org/uniprot/A0A8I5KX50> , <https://identifiers.org/uniprot/A0A8I5QKZ6> , <https://identifiers.org/uniprot/A0A8I5KWF7> , <https://identifiers.org/uniprot/H7C155> , <https://identifiers.org/uniprot/A0A8I5KRD1> , <https://identifiers.org/uniprot/A0A8I5KYC4> , <https://identifiers.org/uniprot/A0A0S2Z4L5> , <https://identifiers.org/uniprot/A0A8I5QJG5> , <https://identifiers.org/uniprot/A0A8I5KW44> , <https://identifiers.org/uniprot/L7RRS6> , <https://identifiers.org/uniprot/A0A8I5KTA5> , <https://identifiers.org/uniprot/A0A8I5KR46> , <https://identifiers.org/uniprot/A0A8I5KSI1> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP286_r142061/DataNode/a1257> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A8I5QKU8> , <http://purl.uniprot.org/uniprot/A0A0S2Z4L5> , <http://purl.uniprot.org/uniprot/A0A0B4J1W9> , <http://purl.uniprot.org/uniprot/A0A8I5KT32> , <http://purl.uniprot.org/uniprot/A0A8I5KS16> , <http://purl.uniprot.org/uniprot/A0A8I5KTA5> , <http://purl.uniprot.org/uniprot/A0A0S2Z559> , <http://purl.uniprot.org/uniprot/L7RRS6> , <http://purl.uniprot.org/uniprot/A0A8I5KYC4> , <http://purl.uniprot.org/uniprot/A0A8I5QJG5> , <http://purl.uniprot.org/uniprot/A0A8I5KSI1> , <http://purl.uniprot.org/uniprot/H7C155> , <http://purl.uniprot.org/uniprot/A0A8I5KWF7> , <http://purl.uniprot.org/uniprot/P04049> , <http://purl.uniprot.org/uniprot/A0A8I5KUW4> , <http://purl.uniprot.org/uniprot/A0A8I5KWA9> , <http://purl.uniprot.org/uniprot/A0A8I5KSM4> , <http://purl.uniprot.org/uniprot/A0A8I5KSV6> , <http://purl.uniprot.org/uniprot/A0A8I5KQ33> , <http://purl.uniprot.org/uniprot/A0A8I5QKZ6> , <http://purl.uniprot.org/uniprot/A0A8I5KQV4> , <http://purl.uniprot.org/uniprot/A0A8I5KTK4> , <http://purl.uniprot.org/uniprot/A0A8I5KR46> , <http://purl.uniprot.org/uniprot/A0A8I5KSB0> , <http://purl.uniprot.org/uniprot/A0A8I5KW44> , <http://purl.uniprot.org/uniprot/A0A8I5KYP5> , <http://purl.uniprot.org/uniprot/A0A8I5KX50> , <http://purl.uniprot.org/uniprot/A0A8I5KWS9> , <http://purl.uniprot.org/uniprot/A0A8I5KRD1> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/5894> .

<http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/d3e2c>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP286_r142061> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP286_r142061/Interaction/d3e2c> ;
        wp:participants   <https://identifiers.org/ncbigene/6654> , <https://identifiers.org/ncbigene/2885> ;
        wp:source         <https://identifiers.org/ncbigene/2885> ;
        wp:target         <https://identifiers.org/ncbigene/6654> .

<https://identifiers.org/ncbigene/5781>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "PTPN11" ;
        dc:identifier       <https://identifiers.org/ncbigene/5781> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "5781" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/id7307129b> , <https://identifiers.org/wikipathways/WP286_r142061> , <http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/id925298d1> , <http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/idf19f16de> , <http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/id147d1aac> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000179295> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/5781> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/PTPN11> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A8I5KW48> , <https://identifiers.org/uniprot/A0A0U1RRI0> , <https://identifiers.org/uniprot/A0A8I5QJ58> , <https://identifiers.org/uniprot/A0A8I5KVS6> , <https://identifiers.org/uniprot/A0A8I5QL30> , <https://identifiers.org/uniprot/A0A8I5KRZ3> , <https://identifiers.org/uniprot/A0A1W2PPU4> , <https://identifiers.org/uniprot/H0YF12> , <https://identifiers.org/uniprot/Q06124> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP286_r142061/DataNode/b61c5> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A8I5QJ58> , <http://purl.uniprot.org/uniprot/H0YF12> , <http://purl.uniprot.org/uniprot/Q06124> , <http://purl.uniprot.org/uniprot/A0A8I5KVS6> , <http://purl.uniprot.org/uniprot/A0A1W2PPU4> , <http://purl.uniprot.org/uniprot/A0A0U1RRI0> , <http://purl.uniprot.org/uniprot/A0A8I5KRZ3> , <http://purl.uniprot.org/uniprot/A0A8I5KW48> , <http://purl.uniprot.org/uniprot/A0A8I5QL30> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/5781> .

<https://identifiers.org/pmc/PMC12593800>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed Central" ;
        dcterms:identifier  "PMC12593800" ;
        cito:cites          <https://identifiers.org/wikipathways/WP286> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/PMC12593800> .

<https://identifiers.org/ncbigene/7040>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "TGFB1" ;
        dc:identifier       <https://identifiers.org/ncbigene/7040> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "7040" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP286_r142061> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000105329> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/7040> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/TGFB1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A499FJK2> , <https://identifiers.org/uniprot/A0A7I2V5Z9> , <https://identifiers.org/uniprot/A0A7I2YQL8> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP286_r142061/DataNode/d4255> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A7I2YQL8> , <http://purl.uniprot.org/uniprot/A0A7I2V5Z9> , <http://purl.uniprot.org/uniprot/A0A499FJK2> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/7040> .

<https://identifiers.org/ncbigene/3562>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "IL3" ;
        dc:identifier       <https://identifiers.org/ncbigene/3562> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "3562" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/ced91> , <https://identifiers.org/wikipathways/WP286_r142061> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000164399> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/3562> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/IL3> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/P08700> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP286_r142061/DataNode/d2959> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P08700> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/3562> .

<https://identifiers.org/ncbigene/5295>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "PIK3R1" ;
        dc:identifier       <https://identifiers.org/ncbigene/5295> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "5295" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/id6825bb72> , <http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/id2bf42474> , <http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/idd26c2313> , <https://identifiers.org/wikipathways/WP286_r142061> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000145675> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/5295> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/PIK3R1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/E5RJY0> , <https://identifiers.org/uniprot/H0YB27> , <https://identifiers.org/uniprot/A0A8V8TME9> , <https://identifiers.org/uniprot/P27986> , <https://identifiers.org/uniprot/A0A8V8TL14> , <https://identifiers.org/uniprot/A0A8V8TL31> , <https://identifiers.org/uniprot/E5RGI8> , <https://identifiers.org/uniprot/A0A8V8TLE6> , <https://identifiers.org/uniprot/A0A8V8TLF1> , <https://identifiers.org/uniprot/B3KWZ7> , <https://identifiers.org/uniprot/E5RHI0> , <https://identifiers.org/uniprot/E5RK66> , <https://identifiers.org/uniprot/A0A8V8TMF4> , <https://identifiers.org/uniprot/A0A8V8TLF7> , <https://identifiers.org/uniprot/A0A8V8TMF9> , <https://identifiers.org/uniprot/A0A8V8TL10> , <https://identifiers.org/uniprot/H0YBC2> , <https://identifiers.org/uniprot/A0A2X0SFG1> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP286_r142061/DataNode/c1d7b> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A8V8TMF9> , <http://purl.uniprot.org/uniprot/A0A8V8TME9> , <http://purl.uniprot.org/uniprot/A0A8V8TL14> , <http://purl.uniprot.org/uniprot/A0A8V8TL10> , <http://purl.uniprot.org/uniprot/P27986> , <http://purl.uniprot.org/uniprot/A0A8V8TL31> , <http://purl.uniprot.org/uniprot/H0YBC2> , <http://purl.uniprot.org/uniprot/E5RGI8> , <http://purl.uniprot.org/uniprot/A0A8V8TLE6> , <http://purl.uniprot.org/uniprot/A0A8V8TLF7> , <http://purl.uniprot.org/uniprot/B3KWZ7> , <http://purl.uniprot.org/uniprot/E5RHI0> , <http://purl.uniprot.org/uniprot/A0A2X0SFG1> , <http://purl.uniprot.org/uniprot/H0YB27> , <http://purl.uniprot.org/uniprot/A0A8V8TMF4> , <http://purl.uniprot.org/uniprot/A0A8V8TLF1> , <http://purl.uniprot.org/uniprot/E5RK66> , <http://purl.uniprot.org/uniprot/E5RJY0> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/5295> .

<http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/d9687>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP286_r142061> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP286_r142061/Interaction/d9687> ;
        wp:participants   <https://identifiers.org/ncbigene/572> , <https://identifiers.org/ncbigene/598> ;
        wp:source         <https://identifiers.org/ncbigene/598> ;
        wp:target         <https://identifiers.org/ncbigene/572> .

<https://identifiers.org/pmc/PMC7561109>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed Central" ;
        dcterms:identifier  "PMC7561109" ;
        cito:cites          <https://identifiers.org/wikipathways/WP286> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/PMC7561109> .

<http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/e2331>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP286_r142061> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP286_r142061/Interaction/e2331> ;
        wp:participants   <https://identifiers.org/ncbigene/10971> , <https://identifiers.org/ncbigene/572> ;
        wp:source         <https://identifiers.org/ncbigene/572> ;
        wp:target         <https://identifiers.org/ncbigene/10971> .

<https://identifiers.org/ncbigene/5594>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "MAPK1" ;
        dc:identifier       <https://identifiers.org/ncbigene/5594> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "5594" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP286_r142061> , <http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/idc13ff83> , <http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/a0d99> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000100030> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/5594> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/MAPK1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q1HBJ4> , <https://identifiers.org/uniprot/P28482> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP286_r142061/DataNode/cddd0> , <http://rdf.wikipathways.org/Pathway/WP286_r142061/DataNode/c7ad6> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P28482> , <http://purl.uniprot.org/uniprot/Q1HBJ4> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/5594> .

<https://identifiers.org/ncbigene/5566>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "PRKACA" ;
        dc:identifier       <https://identifiers.org/ncbigene/5566> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "5566" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/ba3bc> , <https://identifiers.org/wikipathways/WP286_r142061> , <http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/f9251> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000072062> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/5566> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/PRKACA> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A024R7J0> , <https://identifiers.org/uniprot/K7ERP6> , <https://identifiers.org/uniprot/Q15136> , <https://identifiers.org/uniprot/A0A7I2YQ82> , <https://identifiers.org/uniprot/P17612> , <https://identifiers.org/uniprot/K7ENJ5> , <https://identifiers.org/uniprot/A0A7I2V5J4> , <https://identifiers.org/uniprot/A0A8V8TL59> , <https://identifiers.org/uniprot/K7EMV1> , <https://identifiers.org/uniprot/B7Z708> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP286_r142061/DataNode/a79f3> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A8V8TL59> , <http://purl.uniprot.org/uniprot/P17612> , <http://purl.uniprot.org/uniprot/K7EMV1> , <http://purl.uniprot.org/uniprot/B7Z708> , <http://purl.uniprot.org/uniprot/K7ENJ5> , <http://purl.uniprot.org/uniprot/Q15136> , <http://purl.uniprot.org/uniprot/K7ERP6> , <http://purl.uniprot.org/uniprot/A0A7I2V5J4> , <http://purl.uniprot.org/uniprot/A0A024R7J0> , <http://purl.uniprot.org/uniprot/A0A7I2YQ82> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/5566> .

<https://identifiers.org/ncbigene/7409>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "VAV1" ;
        dc:identifier       <https://identifiers.org/ncbigene/7409> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "7409" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/id2bf42474> , <https://identifiers.org/wikipathways/WP286_r142061> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000141968> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/7409> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/VAV1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/P15498> , <https://identifiers.org/uniprot/A0A0A0MR07> , <https://identifiers.org/uniprot/Q96D37> , <https://identifiers.org/uniprot/F5H5P4> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP286_r142061/DataNode/ad5c7> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/F5H5P4> , <http://purl.uniprot.org/uniprot/Q96D37> , <http://purl.uniprot.org/uniprot/P15498> , <http://purl.uniprot.org/uniprot/A0A0A0MR07> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/7409> .

<http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/idd4e467bf>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP286_r142061> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP286_r142061/Interaction/idd4e467bf> ;
        wp:participants   <https://identifiers.org/ncbigene/5604> , <https://identifiers.org/ncbigene/5894> ;
        wp:source         <https://identifiers.org/ncbigene/5894> ;
        wp:target         <https://identifiers.org/ncbigene/5604> .

<https://doi.org/10.1016%2Fj.tiv.2016.03.009>
        rdf:type            wp:PublicationReference ;
        dc:source           "DOI" ;
        dcterms:identifier  "10.1016/j.tiv.2016.03.009" ;
        cito:cites          <https://identifiers.org/wikipathways/WP286> .

<https://identifiers.org/ncbigene/3055>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "HCK" ;
        dc:identifier       <https://identifiers.org/ncbigene/3055> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "3055" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP286_r142061> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000101336> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/3055> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/HCK> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/P08631> , <https://identifiers.org/uniprot/H7C5P9> , <https://identifiers.org/uniprot/H7BXG4> , <https://identifiers.org/uniprot/J3KPD6> , <https://identifiers.org/uniprot/H0Y3C5> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP286_r142061/DataNode/f58b9> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/H0Y3C5> , <http://purl.uniprot.org/uniprot/P08631> , <http://purl.uniprot.org/uniprot/H7BXG4> , <http://purl.uniprot.org/uniprot/J3KPD6> , <http://purl.uniprot.org/uniprot/H7C5P9> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/3055> .

<https://identifiers.org/ncbigene/5604>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "MAP2K1" ;
        dc:identifier       <https://identifiers.org/ncbigene/5604> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "5604" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/idc13ff83> , <https://identifiers.org/wikipathways/WP286_r142061> , <http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/idd4e467bf> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000169032> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/5604> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/MAP2K1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A8I5KYS7> , <https://identifiers.org/uniprot/A0A8I5QJ96> , <https://identifiers.org/uniprot/A0A8I5QJP8> , <https://identifiers.org/uniprot/A0A8I5KYB4> , <https://identifiers.org/uniprot/H3BRW9> , <https://identifiers.org/uniprot/A0A8I5KVF6> , <https://identifiers.org/uniprot/A0A8I5KXN4> , <https://identifiers.org/uniprot/B4DFY5> , <https://identifiers.org/uniprot/A4QPA9> , <https://identifiers.org/uniprot/A0A8I5KRX5> , <https://identifiers.org/uniprot/A0A8I5QJL9> , <https://identifiers.org/uniprot/Q02750> , <https://identifiers.org/uniprot/A0A8I5QJC1> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP286_r142061/DataNode/b024b> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A8I5QJL9> , <http://purl.uniprot.org/uniprot/H3BRW9> , <http://purl.uniprot.org/uniprot/A0A8I5QJC1> , <http://purl.uniprot.org/uniprot/A0A8I5KYS7> , <http://purl.uniprot.org/uniprot/A0A8I5KYB4> , <http://purl.uniprot.org/uniprot/A0A8I5KVF6> , <http://purl.uniprot.org/uniprot/B4DFY5> , <http://purl.uniprot.org/uniprot/A0A8I5KXN4> , <http://purl.uniprot.org/uniprot/A0A8I5KRX5> , <http://purl.uniprot.org/uniprot/A4QPA9> , <http://purl.uniprot.org/uniprot/A0A8I5QJ96> , <http://purl.uniprot.org/uniprot/A0A8I5QJP8> , <http://purl.uniprot.org/uniprot/Q02750> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/5604> .

<http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/ee3a8>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP286_r142061> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP286_r142061/Interaction/ee3a8> ;
        wp:participants   <https://identifiers.org/ncbigene/6774> ;
        wp:source         <https://identifiers.org/ncbigene/6774> ;
        wp:target         <https://identifiers.org/ncbigene/6774> .

obo:NCBITaxon_9606  obo:NCIT_C179773  "9606" .

<https://identifiers.org/ncbigene/2534>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "FYN" ;
        dc:identifier       <https://identifiers.org/ncbigene/2534> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "2534" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/c9ff4> , <https://identifiers.org/wikipathways/WP286_r142061> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000010810> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/2534> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/FYN> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/E5RFS5> , <https://identifiers.org/uniprot/E5RI25> , <https://identifiers.org/uniprot/E5RIX5> , <https://identifiers.org/uniprot/E5RK23> , <https://identifiers.org/uniprot/E5RFM4> , <https://identifiers.org/uniprot/E5RGT0> , <https://identifiers.org/uniprot/E5RJX7> , <https://identifiers.org/uniprot/E5RH71> , <https://identifiers.org/uniprot/E5RFM0> , <https://identifiers.org/uniprot/E5RFM6> , <https://identifiers.org/uniprot/E5RGM6> , <https://identifiers.org/uniprot/P06241> , <https://identifiers.org/uniprot/E5RHX7> , <https://identifiers.org/uniprot/E5RHF7> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP286_r142061/DataNode/d97f5> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P06241> , <http://purl.uniprot.org/uniprot/E5RIX5> , <http://purl.uniprot.org/uniprot/E5RI25> , <http://purl.uniprot.org/uniprot/E5RH71> , <http://purl.uniprot.org/uniprot/E5RGT0> , <http://purl.uniprot.org/uniprot/E5RFM6> , <http://purl.uniprot.org/uniprot/E5RHF7> , <http://purl.uniprot.org/uniprot/E5RHX7> , <http://purl.uniprot.org/uniprot/E5RFM0> , <http://purl.uniprot.org/uniprot/E5RJX7> , <http://purl.uniprot.org/uniprot/E5RFS5> , <http://purl.uniprot.org/uniprot/E5RK23> , <http://purl.uniprot.org/uniprot/E5RFM4> , <http://purl.uniprot.org/uniprot/E5RGM6> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/2534> .

<https://identifiers.org/ncbigene/10971>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "YWHAQ" ;
        dc:identifier       <https://identifiers.org/ncbigene/10971> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "10971" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP286_r142061> , <http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/e2331> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000134308> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/10971> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/YWHAQ> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/E9PG15> , <https://identifiers.org/uniprot/P27348> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP286_r142061/DataNode/e0ac3> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/E9PG15> , <http://purl.uniprot.org/uniprot/P27348> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/10971> .

<https://identifiers.org/pmc/PMC8751594>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed Central" ;
        dcterms:identifier  "PMC8751594" ;
        cito:cites          <https://identifiers.org/wikipathways/WP286> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/PMC8751594> .

<https://identifiers.org/ncbigene/7529>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "YWHAB" ;
        dc:identifier       <https://identifiers.org/ncbigene/7529> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "7529" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP286_r142061> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000166913> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/7529> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/YWHAB> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A0J9YWE8> , <https://identifiers.org/uniprot/P31946> , <https://identifiers.org/uniprot/A0A0J9YWZ2> , <https://identifiers.org/uniprot/Q4VY19> , <https://identifiers.org/uniprot/V9HWD6> , <https://identifiers.org/uniprot/Q4VY20> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP286_r142061/DataNode/d4052> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q4VY20> , <http://purl.uniprot.org/uniprot/V9HWD6> , <http://purl.uniprot.org/uniprot/P31946> , <http://purl.uniprot.org/uniprot/A0A0J9YWE8> , <http://purl.uniprot.org/uniprot/Q4VY19> , <http://purl.uniprot.org/uniprot/A0A0J9YWZ2> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/7529> .

<http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/idcc4a2fb3>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP286_r142061> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP286_r142061/Interaction/idcc4a2fb3> , <http://rdf.wikipathways.org/Pathway/WP286_r142061/Interaction/id26378499> ;
        wp:participants   <https://identifiers.org/ncbigene/6464> , <https://identifiers.org/ncbigene/1399> , <https://identifiers.org/ncbigene/3635> ;
        wp:source         <https://identifiers.org/ncbigene/6464> ;
        wp:target         <https://identifiers.org/ncbigene/3635> , <https://identifiers.org/ncbigene/1399> .

<https://identifiers.org/wikipathways/WP286_r142061>
        rdf:type               skos:Collection , wp:Pathway ;
        dc:identifier          <https://identifiers.org/wikipathways/WP286> ;
        dc:source              "WikiPathways" ;
        dc:title               "IL3 signaling"@en ;
        dcterms:description    "Interleukin 3 (IL-3) is a potent growth factor belonging to the super family of cytokines. IL-3 is a 20- 32kDa glycoprotein involved in the process of hematopoiesis. It is involved in the proliferation and differentiation of pleuripotent hematopoietic stem cells, progenitor cells and their mature progeny. IL-3 is a growth factor for B lymphocytes. It also activates monocytes and augments survival and propagation of mast cells, eosinophils and stromal cells. IL-3 is secreted predominantly by activated T lymphocytes in response to immunological stimuli and to a lesser extent by mast cells and eosinophils. IL-3 exerts influence on different biological activities, primarily hematopoiesis by associating with the IL-3 receptor. This receptor is a heterodimeric complex and consists of an alpha chain- IL3RA and a beta chain CSF2RB, shared with the receptors for granulocyte macrophage colony stimulating factor and Interleukin-5. When IL-3 binds to CSF2RB receptor, adapter proteins like SHC1, GRB2 and SOS1 are recruited to activate HRAS. HRAS stimulates RAF1 which further activates MAP2K1 and finally MAPK1 and MAPK3. The signals generated through this pathway are then transmitted to the nucleus leading to the activation of various transcription factors such as JUN and FOS which are involved in the regulation of cell growth and differentiation. IL-3 mediated activation of HRAS also inhibits apoptosis through phosphatidyl inositol 3 kinase/ AKT pathway. The activation of AKT1 in response to IL-3 stimulation leads to the phosphorylation of the apoptotic regulator, BCL2-associated agonist of cell death (BAD), its binding to 14-3-3 and sequestration into the cytoplasm. IL-3 stimulation activates Janus kinase 2 (JAK2) by its phosphorylation. JAK2 in turn phosphorylates signal transducer and activator of transcription 5A and 5B. These translocate to the nucleus, serving the purpose of transcription factor for early genes as well as a feedback inhibitor of the JAK-STAT pathway. IL-3, in addition, is known to activate various tyrosine kinases such as LYN, FYN, SRC, SYK, TEC1 and HCK. The interactions and intersections between canonical and noncanonical IL-3 signaling systems are depicted in the pathway map.\n\n\nPlease access this pathway at [NetSlim](http://www.netpath.org/netslim/IL_3_pathway.html) database.\n\nIf you use this pathway, please cite following paper:\nKandasamy, K., Mohan, S. S., Raju, R., Keerthikumar, S., Kumar, G. S. S., Venugopal, A. K., Telikicherla, D., Navarro, J. D., Mathivanan, S., Pecquet, C., Gollapudi, S. K., Tattikota, S. G., Mohan, S., Padhukasahasram, H., Subbannayya, Y., Goel, R., Jacob, H. K. C., Zhong, J., Sekhar, R., Nanjappa, V., Balakrishnan, L., Subbaiah, R., Ramachandra, Y. L., Rahiman, B. A., Prasad, T. S. K., Lin, J., Houtman, J. C. D., Desiderio, S., Renauld, J., Constantinescu, S. N., Ohara, O., Hirano, T., Kubo, M., Singh, S., Khatri, P., Draghici, S., Bader, G. D., Sander, C., Leonard, W. J. and Pandey, A. (2010). NetPath: A public resource of curated signal transduction pathways. <i>Genome Biology</i>. 11:R3." ;
        dcterms:identifier     "WP286" ;
        dcterms:references     <https://identifiers.org/pubmed/20067622> ;
        cito:cites             <https://identifiers.org/pubmed/20067622> ;
        wp:isAbout             <http://rdf.wikipathways.org/Pathway/WP286_r142061> ;
        wp:ontologyTag         obo:PW_0000968 , wp:Curation:AnalysisCollection , obo:PW_0000512 ;
        wp:organism            obo:NCBITaxon_9606 ;
        wp:organismName        "Homo sapiens" ;
        wp:pathwayOntologyTag  obo:PW_0000512 , obo:PW_0000968 ;
        foaf:img               <https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=png&pwTitle=Pathway:WP286&oldid=142061> , <https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=svg&pwTitle=Pathway:WP286&oldid=142061> ;
        foaf:page              <http://www.wikipathways.org/instance/WP286_r142061> .

<http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/id2b420992>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP286_r142061> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP286_r142061/Interaction/id2b420992> ;
        wp:participants   <https://identifiers.org/ncbigene/1439> , <https://identifiers.org/ncbigene/4067> ;
        wp:source         <https://identifiers.org/ncbigene/4067> ;
        wp:target         <https://identifiers.org/ncbigene/1439> .

<http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/e25ad>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP286_r142061> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP286_r142061/Interaction/e25ad> ;
        wp:participants   <https://identifiers.org/ncbigene/6777> ;
        wp:source         <https://identifiers.org/ncbigene/6777> ;
        wp:target         <https://identifiers.org/ncbigene/6777> .

<http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/idb37fa84c>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP286_r142061> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP286_r142061/Interaction/idb37fa84c> ;
        wp:participants   <https://identifiers.org/ncbigene/6777> , <https://identifiers.org/ncbigene/3717> ;
        wp:source         <https://identifiers.org/ncbigene/3717> ;
        wp:target         <https://identifiers.org/ncbigene/6777> .

<https://identifiers.org/ncbigene/5599>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "MAPK8" ;
        dc:identifier       <https://identifiers.org/ncbigene/5599> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "5599" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP286_r142061> , <http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/ida9a93400> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000107643> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/5599> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/MAPK8> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A3B3IRW7> , <https://identifiers.org/uniprot/C9J762> , <https://identifiers.org/uniprot/A1L4K2> , <https://identifiers.org/uniprot/C9JWQ4> , <https://identifiers.org/uniprot/P45983> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP286_r142061/DataNode/f6e0c> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/C9JWQ4> , <http://purl.uniprot.org/uniprot/C9J762> , <http://purl.uniprot.org/uniprot/A0A3B3IRW7> , <http://purl.uniprot.org/uniprot/P45983> , <http://purl.uniprot.org/uniprot/A1L4K2> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/5599> .

<https://identifiers.org/ncbigene/4067>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "LYN" ;
        dc:identifier       <https://identifiers.org/ncbigene/4067> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "4067" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/id2b420992> , <https://identifiers.org/wikipathways/WP286_r142061> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000254087> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/4067> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/LYN> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/P07948> , <https://identifiers.org/uniprot/E5RJ37> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP286_r142061/DataNode/d3049> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P07948> , <http://purl.uniprot.org/uniprot/E5RJ37> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/4067> .

<https://doi.org/10.3389%2Ffimmu.2021.769011>
        rdf:type            wp:PublicationReference ;
        dc:source           "DOI" ;
        dcterms:identifier  "10.3389/fimmu.2021.769011" ;
        cito:cites          <https://identifiers.org/wikipathways/WP286> .

<https://identifiers.org/ncbigene/3725>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "JUN" ;
        dc:identifier       <https://identifiers.org/ncbigene/3725> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "3725" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/ad3ab> , <https://identifiers.org/wikipathways/WP286_r142061> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000177606> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/3725> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/JUN> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/P05412> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP286_r142061/DataNode/a4075> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P05412> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/3725> .

<http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/c760b>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP286_r142061> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP286_r142061/Interaction/c760b> ;
        wp:participants   <https://identifiers.org/ncbigene/6776> , <https://identifiers.org/ncbigene/3717> ;
        wp:source         <https://identifiers.org/ncbigene/3717> ;
        wp:target         <https://identifiers.org/ncbigene/6776> .

<http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/id34a92d86>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP286_r142061> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP286_r142061/Interaction/id34a92d86> ;
        wp:participants   <https://identifiers.org/ncbigene/6714> , <https://identifiers.org/ncbigene/1439> ;
        wp:source         <https://identifiers.org/ncbigene/1439> ;
        wp:target         <https://identifiers.org/ncbigene/6714> .

<http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/bbd5b>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP286_r142061> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP286_r142061/Interaction/bbd5b> ;
        wp:participants   <https://identifiers.org/ncbigene/572> , <https://identifiers.org/ncbigene/207> ;
        wp:source         <https://identifiers.org/ncbigene/207> ;
        wp:target         <https://identifiers.org/ncbigene/572> .

<http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/a3d99>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP286_r142061> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP286_r142061/Interaction/a3d99> ;
        wp:participants   <https://identifiers.org/ncbigene/6776> ;
        wp:source         <https://identifiers.org/ncbigene/6776> ;
        wp:target         <https://identifiers.org/ncbigene/6776> .

<http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/id6825bb72>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP286_r142061> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP286_r142061/Interaction/id6825bb72> ;
        wp:participants   <https://identifiers.org/ncbigene/5295> , <https://identifiers.org/ncbigene/9846> ;
        wp:source         <https://identifiers.org/ncbigene/9846> ;
        wp:target         <https://identifiers.org/ncbigene/5295> .

<https://identifiers.org/ncbigene/6777>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "STAT5B" ;
        dc:identifier       <https://identifiers.org/ncbigene/6777> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "6777" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/e25ad> , <https://identifiers.org/wikipathways/WP286_r142061> , <http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/idb37fa84c> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000173757> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/6777> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/STAT5B> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A8V8TMP4> , <https://identifiers.org/uniprot/A0A8V8TMQ6> , <https://identifiers.org/uniprot/C9J4I3> , <https://identifiers.org/uniprot/A0A8V8TM84> , <https://identifiers.org/uniprot/A0A8V8TM91> , <https://identifiers.org/uniprot/A0A8V8TP16> , <https://identifiers.org/uniprot/A0A8V8TMR0> , <https://identifiers.org/uniprot/A0A8V8TP21> , <https://identifiers.org/uniprot/A0A8V8TMA6> , <https://identifiers.org/uniprot/A0A8V8TP00> , <https://identifiers.org/uniprot/P51692> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP286_r142061/DataNode/a68ce> , <http://rdf.wikipathways.org/Pathway/WP286_r142061/DataNode/edea7> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A8V8TMR0> , <http://purl.uniprot.org/uniprot/A0A8V8TM84> , <http://purl.uniprot.org/uniprot/A0A8V8TM91> , <http://purl.uniprot.org/uniprot/A0A8V8TMQ6> , <http://purl.uniprot.org/uniprot/A0A8V8TMP4> , <http://purl.uniprot.org/uniprot/P51692> , <http://purl.uniprot.org/uniprot/C9J4I3> , <http://purl.uniprot.org/uniprot/A0A8V8TP00> , <http://purl.uniprot.org/uniprot/A0A8V8TP21> , <http://purl.uniprot.org/uniprot/A0A8V8TMA6> , <http://purl.uniprot.org/uniprot/A0A8V8TP16> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/6777> .

<http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/idbdf5c425>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP286_r142061> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP286_r142061/Interaction/idbdf5c425> ;
        wp:participants   <https://identifiers.org/ncbigene/207> , <https://identifiers.org/ncbigene/5296> ;
        wp:source         <https://identifiers.org/ncbigene/5296> ;
        wp:target         <https://identifiers.org/ncbigene/207> .

<http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/f3dae>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP286_r142061> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP286_r142061/Interaction/f3dae> ;
        wp:participants   <https://identifiers.org/ncbigene/2353> , <https://identifiers.org/ncbigene/5595> ;
        wp:source         <https://identifiers.org/ncbigene/5595> ;
        wp:target         <https://identifiers.org/ncbigene/2353> .

<http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/id875cb34c>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP286_r142061> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP286_r142061/Interaction/id875cb34c> ;
        wp:participants   <https://identifiers.org/ncbigene/1439> , <https://identifiers.org/ncbigene/5777> ;
        wp:source         <https://identifiers.org/ncbigene/5777> ;
        wp:target         <https://identifiers.org/ncbigene/1439> .

<http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/id925298d1>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP286_r142061> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP286_r142061/Interaction/id925298d1> ;
        wp:participants   <https://identifiers.org/ncbigene/5781> , <https://identifiers.org/ncbigene/6654> ;
        wp:source         <https://identifiers.org/ncbigene/6654> ;
        wp:target         <https://identifiers.org/ncbigene/5781> .

<https://identifiers.org/pmc/PMC9524193>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed Central" ;
        dcterms:identifier  "PMC9524193" ;
        cito:cites          <https://identifiers.org/wikipathways/WP286> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/PMC9524193> .

<http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/idf19f16de>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP286_r142061> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP286_r142061/Interaction/idf19f16de> ;
        wp:participants   <https://identifiers.org/ncbigene/9846> , <https://identifiers.org/ncbigene/5781> ;
        wp:source         <https://identifiers.org/ncbigene/5781> ;
        wp:target         <https://identifiers.org/ncbigene/9846> .

<http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/id2bf42474>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP286_r142061> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP286_r142061/Interaction/id2bf42474> ;
        wp:participants   <https://identifiers.org/ncbigene/5295> , <https://identifiers.org/ncbigene/7409> ;
        wp:source         <https://identifiers.org/ncbigene/7409> ;
        wp:target         <https://identifiers.org/ncbigene/5295> .

<https://identifiers.org/ncbigene/3717>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "JAK2" ;
        dc:identifier       <https://identifiers.org/ncbigene/3717> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "3717" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/idb37fa84c> , <http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/id9edb602> , <http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/c760b> , <http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/ide95b63c5> , <https://identifiers.org/wikipathways/WP286_r142061> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000096968> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/3717> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/JAK2> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/O60674> , <https://identifiers.org/uniprot/A0A1B0GVR5> , <https://identifiers.org/uniprot/A0A1B0GTR9> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP286_r142061/DataNode/e2b29> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A1B0GVR5> , <http://purl.uniprot.org/uniprot/O60674> , <http://purl.uniprot.org/uniprot/A0A1B0GTR9> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/3717> .

<http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/a00e3>
        rdf:type          wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP286_r142061> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP286_r142061/Interaction/a00e3> .

<http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/a0d99>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP286_r142061> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP286_r142061/Interaction/a0d99> ;
        wp:participants   <https://identifiers.org/ncbigene/5594> , <https://identifiers.org/ncbigene/5595> ;
        wp:source         <https://identifiers.org/ncbigene/5595> ;
        wp:target         <https://identifiers.org/ncbigene/5594> .

<http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/idf2fb1ff8>
        rdf:type          wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP286_r142061> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP286_r142061/Interaction/idf2fb1ff8> .

<http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/id147d1aac>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP286_r142061> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP286_r142061/Interaction/idb2840288> , <http://rdf.wikipathways.org/Pathway/WP286_r142061/Interaction/id147d1aac> ;
        wp:participants   <https://identifiers.org/ncbigene/5781> , <https://identifiers.org/ncbigene/9846> , <https://identifiers.org/ncbigene/2885> ;
        wp:source         <https://identifiers.org/ncbigene/2885> ;
        wp:target         <https://identifiers.org/ncbigene/5781> , <https://identifiers.org/ncbigene/9846> .

<https://identifiers.org/ncbigene/572>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "BAD" ;
        dc:identifier       <https://identifiers.org/ncbigene/572> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "572" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP286_r142061> , <http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/bbd5b> , <http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/ida9a93400> , <http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/d9687> , <http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/e2331> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000002330> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/572> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/BAD> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/F5H1R6> , <https://identifiers.org/uniprot/Q92934> , <https://identifiers.org/uniprot/F5H3B1> , <https://identifiers.org/uniprot/F5GYS3> , <https://identifiers.org/uniprot/A8MXU7> , <https://identifiers.org/uniprot/A0A024R562> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP286_r142061/DataNode/a70e2> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A8MXU7> , <http://purl.uniprot.org/uniprot/F5H1R6> , <http://purl.uniprot.org/uniprot/A0A024R562> , <http://purl.uniprot.org/uniprot/F5GYS3> , <http://purl.uniprot.org/uniprot/Q92934> , <http://purl.uniprot.org/uniprot/F5H3B1> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/572> .

<https://identifiers.org/ncbigene/5293>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "PIK3CD" ;
        dc:identifier       <https://identifiers.org/ncbigene/5293> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "5293" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP286_r142061> , <http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/f9251> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000171608> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/5293> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/PIK3CD> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A8V8TML5> , <https://identifiers.org/uniprot/B7ZM44> , <https://identifiers.org/uniprot/O00329> , <https://identifiers.org/uniprot/A0A8V8TMM0> , <https://identifiers.org/uniprot/A0A2K8FKV1> , <https://identifiers.org/uniprot/A0A8V8TNW9> , <https://identifiers.org/uniprot/A0A8V8TNP1> , <https://identifiers.org/uniprot/F8W9P4> , <https://identifiers.org/uniprot/A0A8V8TM62> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP286_r142061/DataNode/c7ffc> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/F8W9P4> , <http://purl.uniprot.org/uniprot/O00329> , <http://purl.uniprot.org/uniprot/A0A8V8TMM0> , <http://purl.uniprot.org/uniprot/A0A8V8TML5> , <http://purl.uniprot.org/uniprot/A0A2K8FKV1> , <http://purl.uniprot.org/uniprot/A0A8V8TM62> , <http://purl.uniprot.org/uniprot/B7ZM44> , <http://purl.uniprot.org/uniprot/A0A8V8TNW9> , <http://purl.uniprot.org/uniprot/A0A8V8TNP1> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/5293> .

<https://identifiers.org/ncbigene/6464>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "SHC1" ;
        dc:identifier       <https://identifiers.org/ncbigene/6464> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "6464" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/idcc4a2fb3> , <http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/idd4ae3113> , <http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/d85c0> , <https://identifiers.org/wikipathways/WP286_r142061> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000160691> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/6464> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/SHC1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q5T187> , <https://identifiers.org/uniprot/H0Y539> , <https://identifiers.org/uniprot/P29353> , <https://identifiers.org/uniprot/Q5T181> , <https://identifiers.org/uniprot/X6R6D0> , <https://identifiers.org/uniprot/Q5T188> , <https://identifiers.org/uniprot/Q5T182> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP286_r142061/DataNode/d41aa> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q5T182> , <http://purl.uniprot.org/uniprot/X6R6D0> , <http://purl.uniprot.org/uniprot/Q5T187> , <http://purl.uniprot.org/uniprot/H0Y539> , <http://purl.uniprot.org/uniprot/P29353> , <http://purl.uniprot.org/uniprot/Q5T188> , <http://purl.uniprot.org/uniprot/Q5T181> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/6464> .

<https://identifiers.org/ncbigene/6850>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "SYK" ;
        dc:identifier       <https://identifiers.org/ncbigene/6850> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "6850" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP286_r142061> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000165025> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/6850> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/SYK> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A024R244> , <https://identifiers.org/uniprot/P43405> , <https://identifiers.org/uniprot/A0A024R273> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP286_r142061/DataNode/d72bd> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A024R273> , <http://purl.uniprot.org/uniprot/P43405> , <http://purl.uniprot.org/uniprot/A0A024R244> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/6850> .

<https://identifiers.org/ncbigene/5777>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "PTPN6" ;
        dc:identifier       <https://identifiers.org/ncbigene/5777> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "5777" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/id875cb34c> , <https://identifiers.org/wikipathways/WP286_r142061> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000111679> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/5777> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/PTPN6> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/U3KQS1> , <https://identifiers.org/uniprot/Q53XS4> , <https://identifiers.org/uniprot/F5H0N8> , <https://identifiers.org/uniprot/F5H1Z8> , <https://identifiers.org/uniprot/F5H4Z1> , <https://identifiers.org/uniprot/F5H1V7> , <https://identifiers.org/uniprot/F5GXD4> , <https://identifiers.org/uniprot/P29350> , <https://identifiers.org/uniprot/F5GY79> , <https://identifiers.org/uniprot/F5H5H9> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP286_r142061/DataNode/cfb9a> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P29350> , <http://purl.uniprot.org/uniprot/U3KQS1> , <http://purl.uniprot.org/uniprot/F5H1Z8> , <http://purl.uniprot.org/uniprot/Q53XS4> , <http://purl.uniprot.org/uniprot/F5H5H9> , <http://purl.uniprot.org/uniprot/F5H4Z1> , <http://purl.uniprot.org/uniprot/F5GXD4> , <http://purl.uniprot.org/uniprot/F5H0N8> , <http://purl.uniprot.org/uniprot/F5H1V7> , <http://purl.uniprot.org/uniprot/F5GY79> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/5777> .

<https://identifiers.org/ncbigene/1439>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "CSF2RB" ;
        dc:identifier       <https://identifiers.org/ncbigene/1439> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "1439" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/id2b420992> , <http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/c4de7> , <http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/id875cb34c> , <http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/id34a92d86> , <https://identifiers.org/wikipathways/WP286_r142061> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000100368> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/1439> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/CSF2RB> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/P32927> , <https://identifiers.org/uniprot/B0QY07> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP286_r142061/DataNode/a385f> , <http://rdf.wikipathways.org/Pathway/WP286_r142061/DataNode/a13c0> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P32927> , <http://purl.uniprot.org/uniprot/B0QY07> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/1439> .

<https://identifiers.org/ncbigene/598>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "BCL2L1" ;
        dc:identifier       <https://identifiers.org/ncbigene/598> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "598" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/b8f66> , <http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/d9687> , <https://identifiers.org/wikipathways/WP286_r142061> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000171552> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/598> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/BCL2L1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A7I2V597> , <https://identifiers.org/uniprot/A0A0S2Z3C5> , <https://identifiers.org/uniprot/Q5TE63> , <https://identifiers.org/uniprot/Q5QP56> , <https://identifiers.org/uniprot/Q9H1R6> , <https://identifiers.org/uniprot/Q5TE64> , <https://identifiers.org/uniprot/Q5QP59> , <https://identifiers.org/uniprot/Q07817> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP286_r142061/DataNode/a78f7> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A7I2V597> , <http://purl.uniprot.org/uniprot/Q5TE63> , <http://purl.uniprot.org/uniprot/Q5TE64> , <http://purl.uniprot.org/uniprot/Q9H1R6> , <http://purl.uniprot.org/uniprot/Q5QP59> , <http://purl.uniprot.org/uniprot/Q5QP56> , <http://purl.uniprot.org/uniprot/A0A0S2Z3C5> , <http://purl.uniprot.org/uniprot/Q07817> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/598> .

<https://identifiers.org/ncbigene/969>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "CD69" ;
        dc:identifier       <https://identifiers.org/ncbigene/969> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "969" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP286_r142061> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000110848> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/969> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/CD69> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q07108> , <https://identifiers.org/uniprot/Q53ZX0> , <https://identifiers.org/uniprot/B4E009> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP286_r142061/DataNode/b7e2f> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q53ZX0> , <http://purl.uniprot.org/uniprot/Q07108> , <http://purl.uniprot.org/uniprot/B4E009> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/969> .

<https://identifiers.org/ncbigene/6776>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "STAT5A" ;
        dc:identifier       <https://identifiers.org/ncbigene/6776> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "6776" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/id7307129b> , <http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/c760b> , <https://identifiers.org/wikipathways/WP286_r142061> , <http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/a3d99> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000126561> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/6776> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/STAT5A> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A7I2V380> , <https://identifiers.org/uniprot/A0A384N5W4> , <https://identifiers.org/uniprot/A0A7I2YQY3> , <https://identifiers.org/uniprot/K7EK35> , <https://identifiers.org/uniprot/A0A7I2YQF1> , <https://identifiers.org/uniprot/P42229> , <https://identifiers.org/uniprot/K7EIF9> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP286_r142061/DataNode/a9973> , <http://rdf.wikipathways.org/Pathway/WP286_r142061/DataNode/e75d1> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A7I2YQF1> , <http://purl.uniprot.org/uniprot/A0A384N5W4> , <http://purl.uniprot.org/uniprot/A0A7I2YQY3> , <http://purl.uniprot.org/uniprot/K7EIF9> , <http://purl.uniprot.org/uniprot/K7EK35> , <http://purl.uniprot.org/uniprot/P42229> , <http://purl.uniprot.org/uniprot/A0A7I2V380> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/6776> .

<https://identifiers.org/ncbigene/2353>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "FOS" ;
        dc:identifier       <https://identifiers.org/ncbigene/2353> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "2353" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/f3dae> , <https://identifiers.org/wikipathways/WP286_r142061> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000170345> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/2353> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/FOS> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/G3V5N9> , <https://identifiers.org/uniprot/G3V2V7> , <https://identifiers.org/uniprot/Q6FG41> , <https://identifiers.org/uniprot/P01100> , <https://identifiers.org/uniprot/H0YJM3> , <https://identifiers.org/uniprot/G3V5J9> , <https://identifiers.org/uniprot/G3V5N7> , <https://identifiers.org/uniprot/G3V289> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP286_r142061/DataNode/fa00b> , <http://rdf.wikipathways.org/Pathway/WP286_r142061/DataNode/dc8a9> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/G3V5N7> , <http://purl.uniprot.org/uniprot/G3V2V7> , <http://purl.uniprot.org/uniprot/G3V289> , <http://purl.uniprot.org/uniprot/P01100> , <http://purl.uniprot.org/uniprot/Q6FG41> , <http://purl.uniprot.org/uniprot/H0YJM3> , <http://purl.uniprot.org/uniprot/G3V5J9> , <http://purl.uniprot.org/uniprot/G3V5N9> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/2353> .

<http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/c4de7>
        rdf:type          wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP286_r142061> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP286_r142061/Interaction/c4de7> ;
        wp:participants   <https://identifiers.org/ncbigene/1439> .

<http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/idf11455c2>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP286_r142061> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP286_r142061/Interaction/idf11455c2> ;
        wp:participants   <https://identifiers.org/ncbigene/596> , <https://identifiers.org/ncbigene/207> ;
        wp:source         <https://identifiers.org/ncbigene/207> ;
        wp:target         <https://identifiers.org/ncbigene/596> .

<http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/f9251>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP286_r142061> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP286_r142061/Interaction/f9251> ;
        wp:participants   <https://identifiers.org/ncbigene/5566> , <https://identifiers.org/ncbigene/5293> ;
        wp:source         <https://identifiers.org/ncbigene/5293> ;
        wp:target         <https://identifiers.org/ncbigene/5566> .

<http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/id9edb602>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP286_r142061> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP286_r142061/Interaction/id9edb602> ;
        wp:participants   <https://identifiers.org/ncbigene/3716> , <https://identifiers.org/ncbigene/3717> ;
        wp:source         <https://identifiers.org/ncbigene/3717> ;
        wp:target         <https://identifiers.org/ncbigene/3716> .

<https://identifiers.org/ncbigene/3716>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "JAK1" ;
        dc:identifier       <https://identifiers.org/ncbigene/3716> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "3716" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/e9d5e> , <https://identifiers.org/wikipathways/WP286_r142061> , <http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/id9edb602> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000162434> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/3716> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/JAK1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A8V8TN11> , <https://identifiers.org/uniprot/A0A5F9ZI01> , <https://identifiers.org/uniprot/A0A8V8TN56> , <https://identifiers.org/uniprot/A0A5F9ZHN8> , <https://identifiers.org/uniprot/A0A5F9ZHI1> , <https://identifiers.org/uniprot/A0A5F9ZH73> , <https://identifiers.org/uniprot/P23458> , <https://identifiers.org/uniprot/A0A8V8TPG3> , <https://identifiers.org/uniprot/A0A5F9ZH07> , <https://identifiers.org/uniprot/A0A8V8TPQ9> , <https://identifiers.org/uniprot/A0A5F9ZHW0> , <https://identifiers.org/uniprot/A0A8V8TMY8> , <https://identifiers.org/uniprot/A0A0A0N0M2> , <https://identifiers.org/uniprot/A0A5F9ZI39> , <https://identifiers.org/uniprot/A0A5F9ZHK2> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP286_r142061/DataNode/f407b> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A8V8TPQ9> , <http://purl.uniprot.org/uniprot/A0A8V8TN11> , <http://purl.uniprot.org/uniprot/A0A5F9ZI01> , <http://purl.uniprot.org/uniprot/A0A5F9ZH07> , <http://purl.uniprot.org/uniprot/A0A8V8TN56> , <http://purl.uniprot.org/uniprot/A0A5F9ZHI1> , <http://purl.uniprot.org/uniprot/A0A0A0N0M2> , <http://purl.uniprot.org/uniprot/A0A5F9ZHN8> , <http://purl.uniprot.org/uniprot/A0A5F9ZHW0> , <http://purl.uniprot.org/uniprot/A0A5F9ZHK2> , <http://purl.uniprot.org/uniprot/A0A5F9ZH73> , <http://purl.uniprot.org/uniprot/P23458> , <http://purl.uniprot.org/uniprot/A0A8V8TPG3> , <http://purl.uniprot.org/uniprot/A0A5F9ZI39> , <http://purl.uniprot.org/uniprot/A0A8V8TMY8> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/3716> .

<https://identifiers.org/ncbigene/6714>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "SRC" ;
        dc:identifier       <https://identifiers.org/ncbigene/6714> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "6714" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/id34a92d86> , <http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/c8b65> , <https://identifiers.org/wikipathways/WP286_r142061> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000197122> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/6714> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/SRC> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A8I5KYU4> , <https://identifiers.org/uniprot/P12931> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP286_r142061/DataNode/df872> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P12931> , <http://purl.uniprot.org/uniprot/A0A8I5KYU4> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/6714> .

<https://identifiers.org/pmc/PMC9646470>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed Central" ;
        dcterms:identifier  "PMC9646470" ;
        cito:cites          <https://identifiers.org/wikipathways/WP286> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/PMC9646470> .

<http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/ba3bc>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP286_r142061> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP286_r142061/Interaction/ba3bc> ;
        wp:participants   <https://identifiers.org/ncbigene/596> , <https://identifiers.org/ncbigene/5566> ;
        wp:source         <https://identifiers.org/ncbigene/5566> ;
        wp:target         <https://identifiers.org/ncbigene/596> .

<https://identifiers.org/ncbigene/942>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "CD86" ;
        dc:identifier       <https://identifiers.org/ncbigene/942> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "942" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP286_r142061> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000114013> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/942> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/CD86> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/C9JXS1> , <https://identifiers.org/uniprot/P42081> , <https://identifiers.org/uniprot/H7C4F8> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP286_r142061/DataNode/e8333> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/H7C4F8> , <http://purl.uniprot.org/uniprot/C9JXS1> , <http://purl.uniprot.org/uniprot/P42081> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/942> .

<http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/ida9a93400>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP286_r142061> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP286_r142061/Interaction/ida9a93400> ;
        wp:participants   <https://identifiers.org/ncbigene/572> , <https://identifiers.org/ncbigene/5599> ;
        wp:source         <https://identifiers.org/ncbigene/5599> ;
        wp:target         <https://identifiers.org/ncbigene/572> .

<https://identifiers.org/wikipathways/WP286>
        pav:hasVersion  <https://identifiers.org/wikipathways/WP286_r142061> .

<https://identifiers.org/ncbigene/2885>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "GRB2" ;
        dc:identifier       <https://identifiers.org/ncbigene/2885> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "2885" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/d3e2c> , <https://identifiers.org/wikipathways/WP286_r142061> , <http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/id147d1aac> , <http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/idd4ae3113> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000177885> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/2885> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/GRB2> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/J3KT38> , <https://identifiers.org/uniprot/B0LPF3> , <https://identifiers.org/uniprot/J3QRL5> , <https://identifiers.org/uniprot/P62993> , <https://identifiers.org/uniprot/J3QLF6> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP286_r142061/DataNode/fc176> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/B0LPF3> , <http://purl.uniprot.org/uniprot/J3KT38> , <http://purl.uniprot.org/uniprot/J3QRL5> , <http://purl.uniprot.org/uniprot/J3QLF6> , <http://purl.uniprot.org/uniprot/P62993> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/2885> .

<https://identifiers.org/ncbigene/3265>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "HRAS" ;
        dc:identifier       <https://identifiers.org/ncbigene/3265> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "3265" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/b32e9> , <http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/d42f8> , <https://identifiers.org/wikipathways/WP286_r142061> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000174775> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/3265> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/HRAS> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A804HKM6> , <https://identifiers.org/uniprot/A0A804HJ06> , <https://identifiers.org/uniprot/X5D945> , <https://identifiers.org/uniprot/P01112> , <https://identifiers.org/uniprot/A0A8C8MQR2> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP286_r142061/DataNode/cc2e0> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A8C8MQR2> , <http://purl.uniprot.org/uniprot/X5D945> , <http://purl.uniprot.org/uniprot/P01112> , <http://purl.uniprot.org/uniprot/A0A804HJ06> , <http://purl.uniprot.org/uniprot/A0A804HKM6> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/3265> .

<http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/b8f66>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP286_r142061> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP286_r142061/Interaction/b8f66> ;
        wp:participants   <https://identifiers.org/ncbigene/598> , <https://identifiers.org/ncbigene/207> ;
        wp:source         <https://identifiers.org/ncbigene/207> ;
        wp:target         <https://identifiers.org/ncbigene/598> .

<http://rdf.wikipathways.org/Pathway/WP286_r142061/WP/Interaction/idd4ae3113>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP286_r142061> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP286_r142061/Interaction/idd4ae3113> ;
        wp:participants   <https://identifiers.org/ncbigene/2885> , <https://identifiers.org/ncbigene/6464> ;
        wp:source         <https://identifiers.org/ncbigene/6464> ;
        wp:target         <https://identifiers.org/ncbigene/2885> .
