@prefix biopax:  <http://www.biopax.org/release/biopax-level3.owl#> .
@prefix cito:    <http://purl.org/spar/cito/> .
@prefix dc:      <http://purl.org/dc/elements/1.1/> .
@prefix dcterms: <http://purl.org/dc/terms/> .
@prefix foaf:    <http://xmlns.com/foaf/0.1/> .
@prefix freq:    <http://purl.org/cld/freq/> .
@prefix gpml:    <http://vocabularies.wikipathways.org/gpml#> .
@prefix obo:     <http://purl.obolibrary.org/obo/> .
@prefix owl:     <http://www.w3.org/2002/07/owl#> .
@prefix pav:     <http://purl.org/pav/> .
@prefix prov:    <http://www.w3.org/ns/prov#> .
@prefix rdf:     <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix rdfs:    <http://www.w3.org/2000/01/rdf-schema#> .
@prefix skos:    <http://www.w3.org/2004/02/skos/core#> .
@prefix void:    <http://rdfs.org/ns/void#> .
@prefix wp:      <http://vocabularies.wikipathways.org/wp#> .
@prefix wprdf:   <http://rdf.wikipathways.org/> .
@prefix xsd:     <http://www.w3.org/2001/XMLSchema#> .

<https://identifiers.org/ensembl/ENSMUSG00000070348>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "Ccnd1" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSMUSG00000070348> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSMUSG00000070348" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP3979_r108126> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSMUSG00000070348> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/12443> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/P25322> , <https://identifiers.org/uniprot/Q790L7> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q15311862> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP3979_r108126/DataNode/a2134> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P25322> , <http://purl.uniprot.org/uniprot/Q790L7> ;
        foaf:page           <https://www.ensembl.org/id/ENSMUSG00000070348> .

<https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=png&pwTitle=Pathway:WP3979&oldid=108126>
        rdf:type        foaf:Image ;
        dcterms:format  "image/png" .

<https://identifiers.org/ensembl/ENSMUSG00000027184>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "Caprin1" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSMUSG00000027184> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSMUSG00000027184" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP3979_r108126> , <http://rdf.wikipathways.org/Pathway/WP3979_r108126/WP/Interaction/id170787cc> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSMUSG00000027184> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/53872> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A2BH47> , <https://identifiers.org/uniprot/F6YP03> , <https://identifiers.org/uniprot/F6YLI0> , <https://identifiers.org/uniprot/Q60865> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18257988> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP3979_r108126/DataNode/e4c14> , <http://rdf.wikipathways.org/Pathway/WP3979_r108126/DataNode/e700b> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/F6YP03> , <http://purl.uniprot.org/uniprot/Q60865> , <http://purl.uniprot.org/uniprot/F6YLI0> , <http://purl.uniprot.org/uniprot/A2BH47> ;
        foaf:page           <https://www.ensembl.org/id/ENSMUSG00000027184> .

<https://identifiers.org/wikipathways/WP3979>
        pav:hasVersion  <https://identifiers.org/wikipathways/WP3979_r108126> .

<https://identifiers.org/ensembl/ENSMUSG00000022346>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "Myc" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSMUSG00000022346> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSMUSG00000022346" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP3979_r108126> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSMUSG00000022346> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/17869> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/E0CZD1> , <https://identifiers.org/uniprot/A0A991B922> , <https://identifiers.org/uniprot/A0A991CU09> , <https://identifiers.org/uniprot/P01108> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18252511> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP3979_r108126/DataNode/a853e> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A991CU09> , <http://purl.uniprot.org/uniprot/E0CZD1> , <http://purl.uniprot.org/uniprot/A0A991B922> , <http://purl.uniprot.org/uniprot/P01108> ;
        foaf:page           <https://www.ensembl.org/id/ENSMUSG00000022346> .

<https://identifiers.org/ensembl/ENSMUSG00000018583>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "G3bp1" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSMUSG00000018583> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSMUSG00000018583" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP3979_r108126> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSMUSG00000018583> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/27041> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/P97855> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18255883> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP3979_r108126/DataNode/b536e> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P97855> ;
        foaf:page           <https://www.ensembl.org/id/ENSMUSG00000018583> .

<http://rdf.wikipathways.org/Pathway/WP3979_r108126/WP/Interaction/id170787cc>
        rdf:type          wp:Inhibition , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP3979_r108126> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP3979_r108126/Interaction/id170787cc> ;
        wp:participants   <https://identifiers.org/ensembl/ENSMUSG00000027184> , <https://identifiers.org/ensembl/ENSMUSG00000065395> ;
        wp:source         <https://identifiers.org/ensembl/ENSMUSG00000065395> ;
        wp:target         <https://identifiers.org/ensembl/ENSMUSG00000027184> .

<https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=svg&pwTitle=Pathway:WP3979&oldid=108126>
        rdf:type        foaf:Image ;
        dcterms:format  "image/svg+xml" .

<https://identifiers.org/pubmed/28211508>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "28211508" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP3979_r108126> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/28211508> .

<https://identifiers.org/ensembl/ENSMUSG00000065395>
        rdf:type            wp:DataNode ;
        rdfs:label          "mir193a" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSMUSG00000065395> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSMUSG00000065395" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP3979_r108126/WP/Interaction/id170787cc> , <https://identifiers.org/wikipathways/WP3979_r108126> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP3979_r108126/DataNode/dc565> , <http://rdf.wikipathways.org/Pathway/WP3979_r108126/DataNode/c4642> , <http://rdf.wikipathways.org/Pathway/WP3979_r108126/DataNode/d91b0> , <http://rdf.wikipathways.org/Pathway/WP3979_r108126/DataNode/feda0> , <http://rdf.wikipathways.org/Pathway/WP3979_r108126/DataNode/b2cbd> , <http://rdf.wikipathways.org/Pathway/WP3979_r108126/DataNode/eba4e> ;
        foaf:page           <https://www.ensembl.org/id/ENSMUSG00000065395> .

<https://identifiers.org/ensembl/ENSMUSG00000000184>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "Ccnd2" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSMUSG00000000184> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSMUSG00000000184" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP3979_r108126> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSMUSG00000000184> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/12444> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A0J9YU51> , <https://identifiers.org/uniprot/Q9D8L9> , <https://identifiers.org/uniprot/Q4FK45> , <https://identifiers.org/uniprot/P30280> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18248164> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP3979_r108126/DataNode/e4c84> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P30280> , <http://purl.uniprot.org/uniprot/Q9D8L9> , <http://purl.uniprot.org/uniprot/A0A0J9YU51> , <http://purl.uniprot.org/uniprot/Q4FK45> ;
        foaf:page           <https://www.ensembl.org/id/ENSMUSG00000000184> .

<https://identifiers.org/ensembl/ENSMUSG00000030681>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "Mvp" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSMUSG00000030681> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSMUSG00000030681" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP3979_r108126> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSMUSG00000030681> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/78388> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/D3Z2N7> , <https://identifiers.org/uniprot/E9Q3X0> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18269298> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP3979_r108126/DataNode/e3ee7> , <http://rdf.wikipathways.org/Pathway/WP3979_r108126/DataNode/d1867> , <http://rdf.wikipathways.org/Pathway/WP3979_r108126/DataNode/b6b40> , <http://rdf.wikipathways.org/Pathway/WP3979_r108126/DataNode/b0fa7> , <http://rdf.wikipathways.org/Pathway/WP3979_r108126/DataNode/d2f66> , <http://rdf.wikipathways.org/Pathway/WP3979_r108126/DataNode/fb94f> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/D3Z2N7> , <http://purl.uniprot.org/uniprot/E9Q3X0> ;
        foaf:page           <https://www.ensembl.org/id/ENSMUSG00000030681> .

obo:NCBITaxon_10090  obo:NCIT_C179773  "10090" .

<https://identifiers.org/wikipathways/WP3979_r108126>
        rdf:type               wp:Pathway , skos:Collection ;
        dc:identifier          <https://identifiers.org/wikipathways/WP3979> ;
        dc:source              "WikiPathways" ;
        dc:title               "mir-193a and MVP in colon cancer metastasis"@en ;
        dcterms:description    "Proposed model for the mechanism of colon cancer metastasis to the liver involves exporting miR-193a via exosomes sorted by major vault protein (MVP). \nIn pre-metastatic cells miR-193a suppresses mouse colon cancer progression by directly targeting Caprin1, which is known to positively regulate the cell cycle and cell proliferation. Higher levels of miR-193a in tumor cells causes of cell cycle G1 arrest and cell proliferation repression  through reduction of Caprin1 expression. In metatstatic cells, increased levels of MVP leads to MVP-mediated selective sorting of tumor suppressor miRNA into exosomes, which promotes tumor progression." ;
        dcterms:identifier     "WP3979" ;
        dcterms:references     <https://identifiers.org/pubmed/28211508> ;
        cito:cites             <https://identifiers.org/pubmed/28211508> ;
        wp:diseaseOntologyTag  obo:DOID_219 ;
        wp:isAbout             <http://rdf.wikipathways.org/Pathway/WP3979_r108126> ;
        wp:ontologyTag         obo:PW_0001551 , wp:Curation:ExRNA , obo:PW_0000605 , obo:PW_0000808 , wp:Curation:AnalysisCollection , obo:DOID_219 ;
        wp:organism            obo:NCBITaxon_10090 ;
        wp:organismName        "Mus musculus" ;
        wp:pathwayOntologyTag  obo:PW_0000605 , obo:PW_0001551 , obo:PW_0000808 ;
        foaf:img               <https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=png&pwTitle=Pathway:WP3979&oldid=108126> , <https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=svg&pwTitle=Pathway:WP3979&oldid=108126> ;
        foaf:page              <http://www.wikipathways.org/instance/WP3979_r108126> .
