@prefix biopax:  <http://www.biopax.org/release/biopax-level3.owl#> .
@prefix cito:    <http://purl.org/spar/cito/> .
@prefix dc:      <http://purl.org/dc/elements/1.1/> .
@prefix dcterms: <http://purl.org/dc/terms/> .
@prefix foaf:    <http://xmlns.com/foaf/0.1/> .
@prefix freq:    <http://purl.org/cld/freq/> .
@prefix gpml:    <http://vocabularies.wikipathways.org/gpml#> .
@prefix obo:     <http://purl.obolibrary.org/obo/> .
@prefix owl:     <http://www.w3.org/2002/07/owl#> .
@prefix pav:     <http://purl.org/pav/> .
@prefix prov:    <http://www.w3.org/ns/prov#> .
@prefix rdf:     <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix rdfs:    <http://www.w3.org/2000/01/rdf-schema#> .
@prefix skos:    <http://www.w3.org/2004/02/skos/core#> .
@prefix void:    <http://rdfs.org/ns/void#> .
@prefix wp:      <http://vocabularies.wikipathways.org/wp#> .
@prefix wprdf:   <http://rdf.wikipathways.org/> .
@prefix xsd:     <http://www.w3.org/2001/XMLSchema#> .

<https://identifiers.org/pubmed/20167242>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "20167242" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/d2bcd> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/a036f> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/d7286> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/fc91b> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/dfc95> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/af51b> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/e39b8> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/c29dc> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/a08be> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/a5b51> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/dd399> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/f3bf4> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/20167242> .

<https://identifiers.org/ensembl/ENSG00000138593>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "SECISBP2L" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000138593> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000138593" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Complex/b8acc> , <https://identifiers.org/wikipathways/WP4746_r140519> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000138593> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/9728> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/SECISBP2L> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/H0YKY4> , <https://identifiers.org/uniprot/Q93073> , <https://identifiers.org/uniprot/A0A024R5R0> , <https://identifiers.org/uniprot/J3KPI1> , <https://identifiers.org/uniprot/H0YNT4> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18034621> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/fbdf8> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/H0YNT4> , <http://purl.uniprot.org/uniprot/Q93073> , <http://purl.uniprot.org/uniprot/A0A024R5R0> , <http://purl.uniprot.org/uniprot/H0YKY4> , <http://purl.uniprot.org/uniprot/J3KPI1> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000138593> .

<https://identifiers.org/wikipathways/WP3804>
        rdf:type            wp:DataNode , wp:Pathway ;
        rdfs:label          "Cell cycle arrest" ;
        dc:identifier       <https://identifiers.org/wikipathways/WP3804> ;
        dc:source           "WikiPathways" ;
        dcterms:identifier  "WP3804" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/f6278> , <https://identifiers.org/wikipathways/WP4746_r140519> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/d5136> ;
        foaf:page           <https://www.wikipathways.org/instance/WP3804> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/d56a8>
        rdf:type            wp:Interaction , wp:Stimulation , wp:DirectedInteraction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/27681418> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/d56a8> ;
        wp:participants     <https://identifiers.org/ensembl/ENSG00000174775> , <https://identifiers.org/ensembl/ENSG00000072133> ;
        wp:source           <https://identifiers.org/ensembl/ENSG00000174775> ;
        wp:target           <https://identifiers.org/ensembl/ENSG00000072133> .

<https://identifiers.org/ensembl/ENSG00000109819>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "PCG-1" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000109819> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000109819" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/f0352> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/af4ed> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/dc028> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000109819> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/10891> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/PPARGC1A> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A087WVW3> , <https://identifiers.org/uniprot/A0A087WTJ3> , <https://identifiers.org/uniprot/Q9UBK2> , <https://identifiers.org/uniprot/A0A024R9Q9> , <https://identifiers.org/uniprot/D6RBF3> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18035922> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/cfd6f> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/D6RBF3> , <http://purl.uniprot.org/uniprot/A0A087WVW3> , <http://purl.uniprot.org/uniprot/A0A087WTJ3> , <http://purl.uniprot.org/uniprot/Q9UBK2> , <http://purl.uniprot.org/uniprot/A0A024R9Q9> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000109819> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/a1f30>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4746_r140519> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/a1f30> ;
        wp:participants   <https://identifiers.org/chebi/CHEBI:15378> , <https://identifiers.org/ensembl/ENSG00000109424> ;
        wp:source         <https://identifiers.org/ensembl/ENSG00000109424> ;
        wp:target         <https://identifiers.org/chebi/CHEBI:15378> .

<https://identifiers.org/uniprot/Q7LBC6>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "JMJD1B" ;
        dc:identifier       <https://identifiers.org/uniprot/Q7LBC6> ;
        dc:source           "UniProtKB" ;
        dcterms:identifier  "Q7LBC6" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/da923> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/bcb57> , <https://identifiers.org/wikipathways/WP4746_r140519> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000120733> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/51780> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/KDM3B> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q7LBC6> , <https://identifiers.org/uniprot/H0Y946> , <https://identifiers.org/uniprot/H0Y9V5> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/c7970> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/H0Y9V5> , <http://purl.uniprot.org/uniprot/Q7LBC6> , <http://purl.uniprot.org/uniprot/H0Y946> ;
        foaf:page           <http://www.uniprot.org/uniprot/Q7LBC6> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/d7286>
        rdf:type            wp:Interaction , wp:DirectedInteraction , wp:Catalysis ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/20167242> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/d7286> ;
        wp:participants     <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/dfc95> , <https://identifiers.org/ensembl/ENSG00000009765> ;
        wp:source           <https://identifiers.org/ensembl/ENSG00000009765> ;
        wp:target           <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/dfc95> .

<https://identifiers.org/uniprot/A0A140TA56>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "PAX8" ;
        dc:identifier       <https://identifiers.org/uniprot/A0A140TA56> ;
        dc:source           "UniProtKB" ;
        dcterms:identifier  "A0A140TA56" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/f8243> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Complex/ca727> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000125618> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/7849> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/PAX8> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A024R531> , <https://identifiers.org/uniprot/G3V3F3> , <https://identifiers.org/uniprot/A0A140TA56> , <https://identifiers.org/uniprot/H0YJZ5> , <https://identifiers.org/uniprot/A0A7P0T907> , <https://identifiers.org/uniprot/Q06710> , <https://identifiers.org/uniprot/H0YJD1> , <https://identifiers.org/uniprot/R9W7C9> , <https://identifiers.org/uniprot/A0A024R524> , <https://identifiers.org/uniprot/A0A024R4X8> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/e99fc> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A024R4X8> , <http://purl.uniprot.org/uniprot/R9W7C9> , <http://purl.uniprot.org/uniprot/H0YJZ5> , <http://purl.uniprot.org/uniprot/G3V3F3> , <http://purl.uniprot.org/uniprot/A0A140TA56> , <http://purl.uniprot.org/uniprot/A0A7P0T907> , <http://purl.uniprot.org/uniprot/H0YJD1> , <http://purl.uniprot.org/uniprot/A0A024R524> , <http://purl.uniprot.org/uniprot/Q06710> , <http://purl.uniprot.org/uniprot/A0A024R531> ;
        foaf:page           <http://www.uniprot.org/uniprot/A0A140TA56> .

<https://identifiers.org/ensembl/ENSG00000168036>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "B-Catenin" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000168036> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000168036" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/a79b0> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/c8f3a> , <https://identifiers.org/wikipathways/WP4746_r140519> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000168036> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/1499> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/CTNNB1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A2R8Y5C3> , <https://identifiers.org/uniprot/A0A2R8Y804> , <https://identifiers.org/uniprot/C9IZ65> , <https://identifiers.org/uniprot/A0A2R8Y6G0> , <https://identifiers.org/uniprot/A0A024R2Q3> , <https://identifiers.org/uniprot/A0A2R8Y5Z1> , <https://identifiers.org/uniprot/A0A2R8Y750> , <https://identifiers.org/uniprot/A0A2R8Y543> , <https://identifiers.org/uniprot/B4DGU4> , <https://identifiers.org/uniprot/A0A2R8YG06> , <https://identifiers.org/uniprot/A0A2R8YCH5> , <https://identifiers.org/uniprot/P35222> , <https://identifiers.org/uniprot/A0A2R8Y7Z0> , <https://identifiers.org/uniprot/A0A2R8Y815> , <https://identifiers.org/uniprot/A0A2R8Y5A3> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q14902794> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/c6842> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/B4DGU4> , <http://purl.uniprot.org/uniprot/A0A2R8Y6G0> , <http://purl.uniprot.org/uniprot/A0A2R8Y5A3> , <http://purl.uniprot.org/uniprot/A0A2R8Y5Z1> , <http://purl.uniprot.org/uniprot/A0A2R8Y5C3> , <http://purl.uniprot.org/uniprot/A0A2R8Y7Z0> , <http://purl.uniprot.org/uniprot/A0A2R8Y750> , <http://purl.uniprot.org/uniprot/A0A2R8Y815> , <http://purl.uniprot.org/uniprot/A0A2R8YCH5> , <http://purl.uniprot.org/uniprot/P35222> , <http://purl.uniprot.org/uniprot/A0A2R8Y543> , <http://purl.uniprot.org/uniprot/A0A2R8Y804> , <http://purl.uniprot.org/uniprot/A0A2R8YG06> , <http://purl.uniprot.org/uniprot/A0A024R2Q3> , <http://purl.uniprot.org/uniprot/C9IZ65> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000168036> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/bc0ce>
        rdf:type            wp:Interaction , wp:Inhibition , wp:DirectedInteraction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/9346240> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/bc0ce> ;
        wp:participants     <https://identifiers.org/ensembl/ENSG00000117020> , <https://identifiers.org/ensembl/ENSG00000002330> ;
        wp:source           <https://identifiers.org/ensembl/ENSG00000117020> ;
        wp:target           <https://identifiers.org/ensembl/ENSG00000002330> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/a742d>
        rdf:type            wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/11533250> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/a742d> ;
        wp:participants     <https://identifiers.org/kegg.pathway/map04310> , <https://identifiers.org/ensembl/ENSG00000162552> ;
        wp:source           <https://identifiers.org/ensembl/ENSG00000162552> ;
        wp:target           <https://identifiers.org/kegg.pathway/map04310> .

<https://identifiers.org/ensembl/ENSG00000103197>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "TSC2" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000103197> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000103197" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Complex/d5116> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/d0f36> , <https://identifiers.org/wikipathways/WP4746_r140519> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/e8b0f> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000103197> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/7249> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/TSC2> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A2R8Y6C9> , <https://identifiers.org/uniprot/A0A2R8Y7X5> , <https://identifiers.org/uniprot/H3BQY7> , <https://identifiers.org/uniprot/Q5HYF7> , <https://identifiers.org/uniprot/A0A2R8YDR3> , <https://identifiers.org/uniprot/A0A2R8Y5F1> , <https://identifiers.org/uniprot/I3L3B1> , <https://identifiers.org/uniprot/A0A2R8YGU4> , <https://identifiers.org/uniprot/A0A2R8Y670> , <https://identifiers.org/uniprot/H3BMQ0> , <https://identifiers.org/uniprot/X5D7Q2> , <https://identifiers.org/uniprot/I3L134> , <https://identifiers.org/uniprot/A0A2R8YEJ8> , <https://identifiers.org/uniprot/A0A2R8YGE6> , <https://identifiers.org/uniprot/A0A2R8YCR8> , <https://identifiers.org/uniprot/P49815> , <https://identifiers.org/uniprot/A0A2R8YDZ2> , <https://identifiers.org/uniprot/A0A2R8Y692> , <https://identifiers.org/uniprot/H3BQK4> , <https://identifiers.org/uniprot/A0A2R8Y5B2> , <https://identifiers.org/uniprot/X5D2U8> , <https://identifiers.org/uniprot/A0A2R8YHA2> , <https://identifiers.org/uniprot/A0A2R8Y7C8> , <https://identifiers.org/uniprot/A0A2R8YGD6> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18032199> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/d7139> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/a5121> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A2R8Y5B2> , <http://purl.uniprot.org/uniprot/A0A2R8Y670> , <http://purl.uniprot.org/uniprot/A0A2R8Y7X5> , <http://purl.uniprot.org/uniprot/A0A2R8YGE6> , <http://purl.uniprot.org/uniprot/P49815> , <http://purl.uniprot.org/uniprot/A0A2R8YEJ8> , <http://purl.uniprot.org/uniprot/A0A2R8YCR8> , <http://purl.uniprot.org/uniprot/A0A2R8Y5F1> , <http://purl.uniprot.org/uniprot/H3BQY7> , <http://purl.uniprot.org/uniprot/Q5HYF7> , <http://purl.uniprot.org/uniprot/H3BMQ0> , <http://purl.uniprot.org/uniprot/A0A2R8YDR3> , <http://purl.uniprot.org/uniprot/A0A2R8YGD6> , <http://purl.uniprot.org/uniprot/A0A2R8Y7C8> , <http://purl.uniprot.org/uniprot/A0A2R8YHA2> , <http://purl.uniprot.org/uniprot/X5D7Q2> , <http://purl.uniprot.org/uniprot/H3BQK4> , <http://purl.uniprot.org/uniprot/A0A2R8Y6C9> , <http://purl.uniprot.org/uniprot/A0A2R8Y692> , <http://purl.uniprot.org/uniprot/I3L3B1> , <http://purl.uniprot.org/uniprot/A0A2R8YGU4> , <http://purl.uniprot.org/uniprot/I3L134> , <http://purl.uniprot.org/uniprot/A0A2R8YDZ2> , <http://purl.uniprot.org/uniprot/X5D2U8> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000103197> .

<https://identifiers.org/chebi/CHEBI:33569>
        rdf:type            wp:DataNode , wp:Metabolite ;
        rdfs:label          "Norepinephrine" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/SFLSHLFXELFNJZ-UHFFFAOYSA-N> ;
        dc:identifier       <https://identifiers.org/chebi/CHEBI:33569> ;
        dc:source           "ChEBI" ;
        dcterms:identifier  "CHEBI:33569" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/abcb7> , <https://identifiers.org/wikipathways/WP4746_r140519> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/de2da> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/c7250> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:33569> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/926> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/SFLSHLFXELFNJZ-UHFFFAOYSA-N> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID951> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q27087994> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/e3142> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/f8531> ;
        foaf:page           <https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:33569> .

<https://identifiers.org/ensembl/ENSG00000138448>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "ITGA" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000138448> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000138448" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Complex/a0028> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Complex/b6566> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000138448> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/3685> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/ITGAV> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A8V8TKG0> , <https://identifiers.org/uniprot/A0A8V8TKU8> , <https://identifiers.org/uniprot/A0A8V8TLW4> , <https://identifiers.org/uniprot/A0A8V8TKT8> , <https://identifiers.org/uniprot/A0A8V8TLW9> , <https://identifiers.org/uniprot/A0A8V8TKF7> , <https://identifiers.org/uniprot/A0A8V8TLP3> , <https://identifiers.org/uniprot/A0A8V8TLN8> , <https://identifiers.org/uniprot/A0A8V8TKI2> , <https://identifiers.org/uniprot/L7RXH0> , <https://identifiers.org/uniprot/P06756> , <https://identifiers.org/uniprot/H7BZG1> , <https://identifiers.org/uniprot/A0A8V8TKH9> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18028029> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/abe34> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/ae9e4> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A8V8TKI2> , <http://purl.uniprot.org/uniprot/A0A8V8TKU8> , <http://purl.uniprot.org/uniprot/A0A8V8TKT8> , <http://purl.uniprot.org/uniprot/H7BZG1> , <http://purl.uniprot.org/uniprot/A0A8V8TKF7> , <http://purl.uniprot.org/uniprot/A0A8V8TLW4> , <http://purl.uniprot.org/uniprot/A0A8V8TLP3> , <http://purl.uniprot.org/uniprot/L7RXH0> , <http://purl.uniprot.org/uniprot/A0A8V8TLW9> , <http://purl.uniprot.org/uniprot/A0A8V8TKG0> , <http://purl.uniprot.org/uniprot/P06756> , <http://purl.uniprot.org/uniprot/A0A8V8TLN8> , <http://purl.uniprot.org/uniprot/A0A8V8TKH9> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000138448> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/cee71>
        rdf:type          wp:Conversion , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4746_r140519> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/cee71> ;
        wp:participants   <https://identifiers.org/chebi/CHEBI:18258> , <https://identifiers.org/chebi/CHEBI:18332> ;
        wp:source         <https://identifiers.org/chebi/CHEBI:18332> ;
        wp:target         <https://identifiers.org/chebi/CHEBI:18258> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/eac33>
        rdf:type            wp:DirectedInteraction , wp:Interaction , wp:Stimulation ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/27681418> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/eac33> ;
        wp:participants     <https://identifiers.org/ensembl/ENSG00000174775> , <https://identifiers.org/ensembl/ENSG00000177885> ;
        wp:source           <https://identifiers.org/ensembl/ENSG00000177885> ;
        wp:target           <https://identifiers.org/ensembl/ENSG00000174775> .

<https://identifiers.org/ensembl/ENSG00000105550>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "FGF21" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000105550> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000105550" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/d5383> , <https://identifiers.org/wikipathways/WP4746_r140519> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/efc69> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/e0070> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000105550> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/26291> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/FGF21> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A7U3L5M7> , <https://identifiers.org/uniprot/Q9NSA1> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q5425475> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/f7e73> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/fc200> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A7U3L5M7> , <http://purl.uniprot.org/uniprot/Q9NSA1> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000105550> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/e9749>
        rdf:type            wp:Interaction , wp:Binding , wp:DirectedInteraction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/27681418> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/e9749> ;
        wp:participants     <https://identifiers.org/ensembl/ENSG00000177885> , <https://identifiers.org/ensembl/ENSG00000115904> ;
        wp:source           <https://identifiers.org/ensembl/ENSG00000115904> ;
        wp:target           <https://identifiers.org/ensembl/ENSG00000177885> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/d235f>
        rdf:type            wp:Stimulation , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/24872083> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/d235f> ;
        wp:participants     <https://identifiers.org/ensembl/ENSG00000135540> , <https://identifiers.org/uniprot/A0A140VJM3> ;
        wp:source           <https://identifiers.org/uniprot/A0A140VJM3> ;
        wp:target           <https://identifiers.org/ensembl/ENSG00000135540> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/b7bb2>
        rdf:type            wp:DirectedInteraction , wp:Binding , wp:Interaction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/17574010> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/b7bb2> ;
        wp:participants     <https://identifiers.org/chebi/CHEBI:18258> , <https://identifiers.org/uniprot/P36021> ;
        wp:source           <https://identifiers.org/chebi/CHEBI:18258> ;
        wp:target           <https://identifiers.org/uniprot/P36021> .

<https://identifiers.org/ensembl/ENSG00000159723>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "AGRP" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000159723> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000159723" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Complex/dddea> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000159723> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/181> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/AGRP> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/C6SUN5> , <https://identifiers.org/uniprot/O00253> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q14872762> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/a409a> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/O00253> , <http://purl.uniprot.org/uniprot/C6SUN5> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000159723> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/a5f46>
        rdf:type            wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/25330987> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/a5f46> ;
        wp:participants     <https://identifiers.org/kegg.pathway/map04330> , <https://identifiers.org/ensembl/ENSG00000148400> ;
        wp:source           <https://identifiers.org/ensembl/ENSG00000148400> ;
        wp:target           <https://identifiers.org/kegg.pathway/map04330> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/cdb14>
        rdf:type          wp:Binding , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4746_r140519> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/cdb14> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000109424> , <https://identifiers.org/chebi/CHEBI:15378> ;
        wp:source         <https://identifiers.org/chebi/CHEBI:15378> ;
        wp:target         <https://identifiers.org/ensembl/ENSG00000109424> .

<https://identifiers.org/uniprot/P13945>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "Beta-3 AR" ;
        dc:identifier       <https://identifiers.org/uniprot/P13945> ;
        dc:source           "UniProtKB" ;
        dcterms:identifier  "P13945" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/de2da> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/c188b> , <https://identifiers.org/wikipathways/WP4746_r140519> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000188778> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/155> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/ADRB3> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/P13945> , <https://identifiers.org/uniprot/A8KAG8> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/ed3ac> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P13945> , <http://purl.uniprot.org/uniprot/A8KAG8> ;
        foaf:page           <http://www.uniprot.org/uniprot/P13945> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/e56cc>
        rdf:type            wp:Interaction , wp:DirectedInteraction , wp:Binding ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/19196800> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/e56cc> ;
        wp:participants     <https://identifiers.org/chebi/CHEBI:16382> , <https://identifiers.org/ensembl/ENSG00000091137> ;
        wp:source           <https://identifiers.org/chebi/CHEBI:16382> ;
        wp:target           <https://identifiers.org/ensembl/ENSG00000091137> .

<https://identifiers.org/ensembl/ENSG00000186350>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "RXR" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000186350> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000186350" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Complex/b06b4> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Complex/ee028> , <https://identifiers.org/wikipathways/WP4746_r140519> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Complex/c8bdf> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Complex/dce5b> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000186350> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/6256> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/RXRA> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/F1D8Q5> , <https://identifiers.org/uniprot/A0A3B3IS44> , <https://identifiers.org/uniprot/P19793> , <https://identifiers.org/uniprot/A0A5F9ZHH6> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q17516011> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/eca6a> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/e24db> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/ef00e> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/b3521> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P19793> , <http://purl.uniprot.org/uniprot/A0A3B3IS44> , <http://purl.uniprot.org/uniprot/A0A5F9ZHH6> , <http://purl.uniprot.org/uniprot/F1D8Q5> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000186350> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/c586d>
        rdf:type            wp:DirectedInteraction , wp:Stimulation , wp:Interaction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/11149600> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/c586d> ;
        wp:participants     <https://identifiers.org/uniprot/Q15136> , <https://identifiers.org/ensembl/ENSG00000125482> ;
        wp:source           <https://identifiers.org/uniprot/Q15136> ;
        wp:target           <https://identifiers.org/ensembl/ENSG00000125482> .

<https://identifiers.org/chebi/CHEBI:18035>
        rdf:type            wp:Metabolite , wp:DataNode ;
        rdfs:label          "DG" , "DAG" ;
        dc:identifier       <https://identifiers.org/chebi/CHEBI:18035> ;
        dc:source           "ChEBI" ;
        dcterms:identifier  "CHEBI:18035" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/f4a25> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/a37c2> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/c658c> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/e2761> , <https://identifiers.org/wikipathways/WP4746_r140519> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:18035> ;
        wp:bdbKeggCompound  <https://identifiers.org/kegg.compound/C00165> ;
        wp:bdbLipidMaps     <https://identifiers.org/lipidmaps/LMGL0201> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q161466> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/af1a7> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/bd395> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/a273d> ;
        owl:sameAs          <https://www.lipidmaps.org/rdf/LMGL0201> ;
        foaf:page           <https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:18035> .

<https://identifiers.org/uniprot/P10827>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "THR" ;
        dc:identifier       <https://identifiers.org/uniprot/P10827> ;
        dc:source           "UniProtKB" ;
        dcterms:identifier  "P10827" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Complex/ee028> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Complex/c8bdf> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Complex/b06b4> , <https://identifiers.org/wikipathways/WP4746_r140519> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000126351> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/7067> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/THRA> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/J3QRW5> , <https://identifiers.org/uniprot/J3QR26> , <https://identifiers.org/uniprot/Q6FH41> , <https://identifiers.org/uniprot/J3QRA9> , <https://identifiers.org/uniprot/J3KTF3> , <https://identifiers.org/uniprot/P10827> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/b576d> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/b4b8b> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/c0a82> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/J3QRW5> , <http://purl.uniprot.org/uniprot/J3QR26> , <http://purl.uniprot.org/uniprot/J3KTF3> , <http://purl.uniprot.org/uniprot/P10827> , <http://purl.uniprot.org/uniprot/Q6FH41> , <http://purl.uniprot.org/uniprot/J3QRA9> ;
        foaf:page           <http://www.uniprot.org/uniprot/P10827> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/af4ed>
        rdf:type            wp:Interaction , wp:Stimulation , wp:DirectedInteraction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/27693079> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/af4ed> ;
        wp:participants     <https://identifiers.org/ensembl/ENSG00000109819> , <https://identifiers.org/ensembl/ENSG00000109424> ;
        wp:source           <https://identifiers.org/ensembl/ENSG00000109819> ;
        wp:target           <https://identifiers.org/ensembl/ENSG00000109424> .

<https://identifiers.org/chebi/CHEBI:85053>
        rdf:type            wp:Metabolite , wp:DataNode ;
        rdfs:label          "Hypothalamic  AMPK" ;
        dc:identifier       <https://identifiers.org/chebi/CHEBI:85053> ;
        dc:source           "ChEBI" ;
        dcterms:identifier  "CHEBI:85053" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/c0740> , <https://identifiers.org/wikipathways/WP4746_r140519> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/c7250> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:85053> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/cb6b7> ;
        foaf:page           <https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:85053> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/b0d4d>
        rdf:type            wp:DirectedInteraction , wp:Inhibition , wp:Interaction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/29997323> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/b0d4d> ;
        wp:participants     <https://identifiers.org/ensembl/ENSG00000166603> , <https://identifiers.org/uniprot/P36021> ;
        wp:source           <https://identifiers.org/uniprot/P36021> ;
        wp:target           <https://identifiers.org/ensembl/ENSG00000166603> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/d0b9f>
        rdf:type          wp:Conversion , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4746_r140519> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/d0b9f> ;
        wp:participants   <https://identifiers.org/chebi/CHEBI:18258> , <https://identifiers.org/chebi/CHEBI:18332> ;
        wp:source         <https://identifiers.org/chebi/CHEBI:18332> ;
        wp:target         <https://identifiers.org/chebi/CHEBI:18258> .

<https://identifiers.org/pubmed/27681418>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "27681418" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/eac33> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/b68fc> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/d5383> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/efc69> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/a3ac8> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/d56a8> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/deb7f> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/e9749> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/27681418> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/Complex/c8bdf>
        rdf:type          wp:Complex , wp:DataNode ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4746_r140519> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Group/c8bdf> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000186350> , <https://identifiers.org/uniprot/P10827> , <https://identifiers.org/chebi/CHEBI:18258> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/d1c5b>
        rdf:type            wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/17574010> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/d1c5b> ;
        wp:participants     <https://identifiers.org/chebi/CHEBI:18258> , <https://identifiers.org/uniprot/P36021> ;
        wp:source           <https://identifiers.org/uniprot/P36021> ;
        wp:target           <https://identifiers.org/chebi/CHEBI:18258> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/c7250>
        rdf:type            wp:DirectedInteraction , wp:Inhibition , wp:Interaction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/20802499> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/c7250> ;
        wp:participants     <https://identifiers.org/chebi/CHEBI:33569> , <https://identifiers.org/chebi/CHEBI:85053> ;
        wp:source           <https://identifiers.org/chebi/CHEBI:85053> ;
        wp:target           <https://identifiers.org/chebi/CHEBI:33569> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/ee727>
        rdf:type            wp:Stimulation , wp:Interaction , wp:DirectedInteraction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/20378719> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/ee727> ;
        wp:participants     <https://identifiers.org/uniprot/A0A0K0K1K3> , <https://identifiers.org/chebi/CHEBI:17489> ;
        wp:source           <https://identifiers.org/uniprot/A0A0K0K1K3> ;
        wp:target           <https://identifiers.org/chebi/CHEBI:17489> .

<https://identifiers.org/kegg.pathway/map00020>
        rdf:type            wp:Pathway , wp:DataNode ;
        rdfs:label          "TCA cycle" ;
        dc:identifier       <https://identifiers.org/kegg.pathway/map00020> ;
        dc:source           "KEGG Pathway" ;
        dcterms:identifier  "map00020" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/b9e67> , <https://identifiers.org/wikipathways/WP4746_r140519> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/fd422> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/dfe23> ;
        foaf:page           <http://www.genome.jp/dbget-bin/www_bget?pathway+map00020> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/a8e9e>
        rdf:type            wp:Interaction , wp:DirectedInteraction , wp:Stimulation ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/21683758> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/a8e9e> ;
        wp:participants     <https://identifiers.org/chebi/CHEBI:29108> , <https://identifiers.org/ensembl/ENSG00000140279> ;
        wp:source           <https://identifiers.org/chebi/CHEBI:29108> ;
        wp:target           <https://identifiers.org/ensembl/ENSG00000140279> .

<https://identifiers.org/ensembl/ENSG00000164690>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "SHH" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000164690> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000164690" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/ddc3d> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/bb9a8> , <https://identifiers.org/wikipathways/WP4746_r140519> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000164690> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/6469> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/SHH> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/F8WEH4> , <https://identifiers.org/uniprot/F8WB84> , <https://identifiers.org/uniprot/Q15465> , <https://identifiers.org/uniprot/C9JC48> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q14860072> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/f51ee> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/f93cc> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/C9JC48> , <http://purl.uniprot.org/uniprot/F8WEH4> , <http://purl.uniprot.org/uniprot/Q15465> , <http://purl.uniprot.org/uniprot/F8WB84> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000164690> .

<https://identifiers.org/chebi/CHEBI:18258>
        rdf:type            wp:Metabolite , wp:DataNode ;
        rdfs:label          "TBG bound T3" , "TTR bound T3" , "T3" , "Albumin bound T3" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/AUYYCJSJGJYCDS-LBPRGKRZSA-N> ;
        dc:identifier       <https://identifiers.org/chebi/CHEBI:18258> ;
        dc:source           "ChEBI" ;
        dcterms:identifier  "CHEBI:18258" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/dc852> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/e64a3> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Complex/ee028> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/d6ae8> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/cdb49> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/d0b9f> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/cee71> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/dd399> , <https://identifiers.org/wikipathways/WP4746_r140519> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Complex/dce5b> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Complex/de5d5> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/c39e7> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/be36b> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/c3b2a> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/c4d63> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Complex/f4317> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Complex/c8bdf> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Complex/b06b4> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/fa15b> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/b7bb2> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/a146f> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/d1c5b> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/b8bcd> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/b9e72> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/d68fa> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/e4011> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/fa968> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/d86d8> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:18258> , <https://identifiers.org/chebi/CHEBI:533015> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/5707> ;
        wp:bdbHmdb          <https://identifiers.org/hmdb/HMDB0000265> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/AUYYCJSJGJYCDS-LBPRGKRZSA-N> ;
        wp:bdbKeggCompound  <https://identifiers.org/kegg.compound/C02465> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID5920> , <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID7048703> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q106345628> , <http://www.wikidata.org/entity/Q327362> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/bc8d8> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/a9d2a> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/a9797> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/d2b6c> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/aa087> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/e7df2> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/d1aac> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/d4370> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/e44d3> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/ca238> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/ac91e> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/b4821> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/ce055> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/ba6f2> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/a527e> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/bd997> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/a7d8b> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/ca49a> ;
        foaf:page           <https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:18258> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/acb64>
        rdf:type            wp:DirectedInteraction , wp:Binding , wp:Interaction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/24463099> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/acb64> ;
        wp:participants     <https://identifiers.org/chebi/CHEBI:17754> , <https://identifiers.org/ensembl/ENSG00000165269> ;
        wp:source           <https://identifiers.org/chebi/CHEBI:17754> ;
        wp:target           <https://identifiers.org/ensembl/ENSG00000165269> .

<https://identifiers.org/chebi/CHEBI:16618>
        rdf:type            wp:Metabolite , wp:DataNode ;
        rdfs:label          "PIP3" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/RQQIRMLGKSPXSE-UQPICLANSA-N> ;
        dc:identifier       <https://identifiers.org/chebi/CHEBI:16618> ;
        dc:source           "ChEBI" ;
        dcterms:identifier  "CHEBI:16618" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/d6efc> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/df053> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:16618> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/34980938> ;
        wp:bdbHmdb          <https://identifiers.org/hmdb/HMDB0004249> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/RQQIRMLGKSPXSE-UQPICLANSA-N> ;
        wp:bdbKeggCompound  <https://identifiers.org/kegg.compound/C05981> ;
        wp:bdbLipidMaps     <https://identifiers.org/lipidmaps/LMGP09010000> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q28797898> , <http://www.wikidata.org/entity/Q130305209> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/c8585> ;
        owl:sameAs          <https://www.lipidmaps.org/rdf/LMGP09010000> ;
        foaf:page           <https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:16618> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/ComplexBinding/b06b4>
        rdf:type          wp:ComplexBinding , wp:Binding , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4746_r140519> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Group/b06b4> ;
        wp:participants   <https://identifiers.org/chebi/CHEBI:18258> , <https://identifiers.org/uniprot/P10827> , <https://identifiers.org/ensembl/ENSG00000186350> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Complex/b06b4> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/b7188>
        rdf:type            wp:DirectedInteraction , wp:Stimulation , wp:Interaction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/18329679> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/b7188> ;
        wp:participants     <https://identifiers.org/uniprot/P28482> , <https://identifiers.org/uniprot/A0A087X0I9> ;
        wp:source           <https://identifiers.org/uniprot/A0A087X0I9> ;
        wp:target           <https://identifiers.org/uniprot/P28482> .

<https://identifiers.org/chebi/CHEBI:17408>
        rdf:type            wp:DataNode , wp:Metabolite ;
        rdfs:label          "MG" ;
        dc:identifier       <https://identifiers.org/chebi/CHEBI:17408> ;
        dc:source           "ChEBI" ;
        dcterms:identifier  "CHEBI:17408" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:17408> ;
        wp:bdbKeggCompound  <https://identifiers.org/kegg.compound/C01885> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q662225> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/e097f> ;
        foaf:page           <https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:17408> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/a3ac8>
        rdf:type            wp:Stimulation , wp:Interaction , wp:DirectedInteraction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/27681418> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/a3ac8> ;
        wp:participants     <https://identifiers.org/ensembl/ENSG00000137154> , <https://identifiers.org/ensembl/ENSG00000108443> ;
        wp:source           <https://identifiers.org/ensembl/ENSG00000108443> ;
        wp:target           <https://identifiers.org/ensembl/ENSG00000137154> .

<https://identifiers.org/ensembl/ENSG00000174775>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "Ras" , "RAS" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000174775> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000174775" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/d56a8> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/cb62d> , <https://identifiers.org/wikipathways/WP4746_r140519> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/eac33> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000174775> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/3265> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/HRAS> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/P01112> , <https://identifiers.org/uniprot/A0A804HJ06> , <https://identifiers.org/uniprot/X5D945> , <https://identifiers.org/uniprot/A0A804HKM6> , <https://identifiers.org/uniprot/A0A8C8MQR2> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/ff3dd> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/fdb8c> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/X5D945> , <http://purl.uniprot.org/uniprot/P01112> , <http://purl.uniprot.org/uniprot/A0A804HJ06> , <http://purl.uniprot.org/uniprot/A0A804HKM6> , <http://purl.uniprot.org/uniprot/A0A8C8MQR2> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000174775> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/f8243>
        rdf:type            wp:Interaction , wp:DirectedInteraction , wp:Stimulation ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/28322461> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/f8243> ;
        wp:participants     <https://identifiers.org/uniprot/A0A140TA56> , <https://identifiers.org/uniprot/A0A087X0I9> ;
        wp:source           <https://identifiers.org/uniprot/A0A087X0I9> ;
        wp:target           <https://identifiers.org/uniprot/A0A140TA56> .

<https://identifiers.org/ensembl/ENSG00000116830>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "TTF2" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000116830> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000116830" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/a744d> , <https://identifiers.org/wikipathways/WP4746_r140519> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Complex/e1401> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000116830> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/8458> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/TTF2> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q9UNY4> , <https://identifiers.org/uniprot/X6RI15> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18032950> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/c764a> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/X6RI15> , <http://purl.uniprot.org/uniprot/Q9UNY4> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000116830> .

<https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=svg&pwTitle=Pathway:WP4746&oldid=140519>
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<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/afd0b>
        rdf:type            wp:Catalysis , wp:Interaction , wp:DirectedInteraction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/28723567> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/afd0b> ;
        wp:participants     <https://identifiers.org/ensembl/ENSG00000077463> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/f0352> ;
        wp:source           <https://identifiers.org/ensembl/ENSG00000077463> ;
        wp:target           <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/f0352> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/b9e67>
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        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/b9e67> ;
        wp:participants     <https://identifiers.org/kegg.pathway/map00020> , <https://identifiers.org/kegg.pathway/map00190> ;
        wp:source           <https://identifiers.org/kegg.pathway/map00020> ;
        wp:target           <https://identifiers.org/kegg.pathway/map00190> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/dd399>
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        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/dd399> ;
        wp:participants     <https://identifiers.org/chebi/CHEBI:18258> , <https://identifiers.org/uniprot/E5RG33> ;
        wp:source           <https://identifiers.org/uniprot/E5RG33> ;
        wp:target           <https://identifiers.org/chebi/CHEBI:18258> .

<https://identifiers.org/pubmed/9346240>
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        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/9346240> .

<https://identifiers.org/ensembl/ENSG00000105641>
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        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000105641> ;
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        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/SLC5A5> ;
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        owl:sameAs          <http://purl.uniprot.org/uniprot/Q92911> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000105641> .

<https://identifiers.org/pubmed/22653837>
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        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/22653837> .

<https://identifiers.org/pubmed/18329679>
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        dc:source           "PubMed" ;
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        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/18329679> .

<https://identifiers.org/pubmed/31076567>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "31076567" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/daf19> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/31076567> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/a146f>
        rdf:type            wp:Interaction , wp:Binding , wp:DirectedInteraction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/8222576> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/a146f> ;
        wp:participants     <https://identifiers.org/uniprot/P36021> , <https://identifiers.org/chebi/CHEBI:18258> ;
        wp:source           <https://identifiers.org/chebi/CHEBI:18258> ;
        wp:target           <https://identifiers.org/uniprot/P36021> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/ae922>
        rdf:type            wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/9346240> , <https://identifiers.org/pubmed/21440011> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/ae922> ;
        wp:participants     <https://identifiers.org/ensembl/ENSG00000132906> , <https://identifiers.org/kegg.pathway/hsa04211> ;
        wp:source           <https://identifiers.org/ensembl/ENSG00000132906> ;
        wp:target           <https://identifiers.org/kegg.pathway/hsa04211> .

<https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=png&pwTitle=Pathway:WP4746&oldid=140519>
        rdf:type        foaf:Image ;
        dcterms:format  "image/png" .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/b8bdc>
        rdf:type            wp:Stimulation , wp:Interaction , wp:DirectedInteraction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
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        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/b8bdc> ;
        wp:participants     <https://identifiers.org/uniprot/A0A087X0I9> , <https://identifiers.org/ensembl/ENSG00000107175> ;
        wp:source           <https://identifiers.org/uniprot/A0A087X0I9> ;
        wp:target           <https://identifiers.org/ensembl/ENSG00000107175> .

<https://identifiers.org/uniprot/Q96AD5>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "ATGL" ;
        dc:identifier       <https://identifiers.org/uniprot/Q96AD5> ;
        dc:source           "UniProtKB" ;
        dcterms:identifier  "Q96AD5" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000177666> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/57104> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/PNPLA2> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q96AD5> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/dd1f4> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q96AD5> ;
        foaf:page           <http://www.uniprot.org/uniprot/Q96AD5> .

<https://identifiers.org/pubmed/8222576>
        rdf:type            wp:PublicationReference ;
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        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/8222576> .

<https://identifiers.org/chebi/CHEBI:75602>
        rdf:type            wp:DataNode , wp:Metabolite ;
        rdfs:label          "TBG bound T4" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/GDPJWJXLKPPEKK-SJAYXVESSA-N> ;
        dc:identifier       <https://identifiers.org/chebi/CHEBI:75602> ;
        dc:source           "ChEBI" ;
        dcterms:identifier  "CHEBI:75602" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/d9f9b> , <https://identifiers.org/wikipathways/WP4746_r140519> ;
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        wp:bdbInChIKey      <https://identifiers.org/inchikey/GDPJWJXLKPPEKK-SJAYXVESSA-N> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID11967651> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q27145419> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/fb04e> ;
        foaf:page           <https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:75602> .

<https://identifiers.org/pubmed/15971998>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "15971998" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/e157f> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/d4a02> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q24536241> ;
        owl:sameAs          <https://doi.org/10.1042%2FBJ20050887> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/15971998> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/d5383>
        rdf:type            wp:DirectedInteraction , wp:Stimulation , wp:Interaction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/27681418> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/d5383> ;
        wp:participants     <https://identifiers.org/ensembl/ENSG00000137154> , <https://identifiers.org/ensembl/ENSG00000105550> ;
        wp:source           <https://identifiers.org/ensembl/ENSG00000137154> ;
        wp:target           <https://identifiers.org/ensembl/ENSG00000105550> .

<https://identifiers.org/chebi/CHEBI:17855>
        rdf:type            wp:Metabolite , wp:DataNode ;
        rdfs:label          "TG" ;
        dc:identifier       <https://identifiers.org/chebi/CHEBI:17855> ;
        dc:source           "ChEBI" ;
        dcterms:identifier  "CHEBI:17855" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:17855> ;
        wp:bdbKeggCompound  <https://identifiers.org/kegg.compound/C00422> ;
        wp:bdbLipidMaps     <https://identifiers.org/lipidmaps/LMGL03010000> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q186319> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/b060c> ;
        owl:sameAs          <https://www.lipidmaps.org/rdf/LMGL03010000> ;
        foaf:page           <https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:17855> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/Complex/c5ef2>
        rdf:type          wp:Complex , wp:DataNode ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4746_r140519> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Group/c5ef2> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000140279> , <https://identifiers.org/ensembl/ENSG00000140274> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/e2761>
        rdf:type            wp:Binding , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
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        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/e2761> ;
        wp:participants     <https://identifiers.org/uniprot/A0A087X0I9> , <https://identifiers.org/chebi/CHEBI:18035> ;
        wp:source           <https://identifiers.org/chebi/CHEBI:18035> ;
        wp:target           <https://identifiers.org/uniprot/A0A087X0I9> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/Complex/e1401>
        rdf:type          wp:Complex , wp:DataNode ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4746_r140519> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Group/e1401> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000116830> , <https://identifiers.org/ensembl/ENSG00000125482> .

<https://identifiers.org/pubmed/29997323>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "29997323" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/fa968> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/bf6ae> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/d9f9b> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/cf0e5> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/b0d4d> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/d6ae8> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/c4d63> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/e4011> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/f3725> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/cac71> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/eea5e> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/29997323> .

<https://identifiers.org/ensembl/ENSG00000167965>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "MLST8" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000167965> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000167965" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Complex/c7580> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000167965> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/64223> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/MLST8> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/H3BPU5> , <https://identifiers.org/uniprot/H3BSZ4> , <https://identifiers.org/uniprot/A0A0A0MR05> , <https://identifiers.org/uniprot/H3BQ74> , <https://identifiers.org/uniprot/Q9BVC4> , <https://identifiers.org/uniprot/H3BR38> , <https://identifiers.org/uniprot/I3L2E7> , <https://identifiers.org/uniprot/H3BR25> , <https://identifiers.org/uniprot/H3BM50> , <https://identifiers.org/uniprot/H3BPT1> , <https://identifiers.org/uniprot/H3BN58> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18045615> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/dc3ae> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/H3BPT1> , <http://purl.uniprot.org/uniprot/I3L2E7> , <http://purl.uniprot.org/uniprot/H3BR38> , <http://purl.uniprot.org/uniprot/H3BSZ4> , <http://purl.uniprot.org/uniprot/H3BR25> , <http://purl.uniprot.org/uniprot/H3BQ74> , <http://purl.uniprot.org/uniprot/A0A0A0MR05> , <http://purl.uniprot.org/uniprot/Q9BVC4> , <http://purl.uniprot.org/uniprot/H3BN58> , <http://purl.uniprot.org/uniprot/H3BPU5> , <http://purl.uniprot.org/uniprot/H3BM50> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000167965> .

<https://identifiers.org/chebi/CHEBI:16474>
        rdf:type            wp:Metabolite , wp:DataNode ;
        rdfs:label          "NADPH" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/ACFIXJIJDZMPPO-NNYOXOHSSA-N> ;
        dc:identifier       <https://identifiers.org/chebi/CHEBI:16474> ;
        dc:source           "ChEBI" ;
        dcterms:identifier  "CHEBI:16474" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/b96dd> , <https://identifiers.org/wikipathways/WP4746_r140519> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:16474> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/5673> ;
        wp:bdbHmdb          <https://identifiers.org/hmdb/HMDB0000221> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/ACFIXJIJDZMPPO-NNYOXOHSSA-N> ;
        wp:bdbKeggCompound  <https://identifiers.org/kegg.compound/C00005> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID5884> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q26841327> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/d8a9e> ;
        foaf:page           <https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:16474> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/a83c5>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4746_r140519> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/a83c5> ;
        wp:participants   <https://identifiers.org/chebi/CHEBI:29101> , <https://identifiers.org/ensembl/ENSG00000105641> ;
        wp:source         <https://identifiers.org/ensembl/ENSG00000105641> ;
        wp:target         <https://identifiers.org/chebi/CHEBI:29101> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/f0518>
        rdf:type            wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/17574010> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/f0518> ;
        wp:participants     <https://identifiers.org/chebi/CHEBI:18332> , <https://identifiers.org/ensembl/ENSG00000139155> ;
        wp:source           <https://identifiers.org/ensembl/ENSG00000139155> ;
        wp:target           <https://identifiers.org/chebi/CHEBI:18332> .

<https://identifiers.org/ensembl/ENSG00000166819>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "PLIN" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000166819> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000166819" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/d3591> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/beb87> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/c5d51> , <https://identifiers.org/wikipathways/WP4746_r140519> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000166819> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/5346> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/PLIN1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/O60240> , <https://identifiers.org/uniprot/H0YM16> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q14897674> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/dd712> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/O60240> , <http://purl.uniprot.org/uniprot/H0YM16> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000166819> .

<https://identifiers.org/pubmed/18467435>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "18467435" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/c8f3a> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/bc893> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/18467435> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/efc69>
        rdf:type            wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/27681418> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/efc69> ;
        wp:participants     <https://identifiers.org/ensembl/ENSG00000105550> ;
        wp:source           <https://identifiers.org/ensembl/ENSG00000105550> ;
        wp:target           <https://identifiers.org/ensembl/ENSG00000105550> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/de2da>
        rdf:type            wp:Binding , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/28448947> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/de2da> ;
        wp:participants     <https://identifiers.org/chebi/CHEBI:33569> , <https://identifiers.org/uniprot/P13945> ;
        wp:source           <https://identifiers.org/chebi/CHEBI:33569> ;
        wp:target           <https://identifiers.org/uniprot/P13945> .

<https://identifiers.org/uniprot/A0A140VJM3>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "PKG" ;
        dc:identifier       <https://identifiers.org/uniprot/A0A140VJM3> ;
        dc:source           "UniProtKB" ;
        dcterms:identifier  "A0A140VJM3" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/c5d51> , <https://identifiers.org/wikipathways/WP4746_r140519> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/ebd7b> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/ebd53> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/d235f> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000138669> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/5593> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/PRKG2> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/B7ZA25> , <https://identifiers.org/uniprot/Q13237> , <https://identifiers.org/uniprot/A0A140VJM3> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/deb28> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A140VJM3> , <http://purl.uniprot.org/uniprot/Q13237> , <http://purl.uniprot.org/uniprot/B7ZA25> ;
        foaf:page           <http://www.uniprot.org/uniprot/A0A140VJM3> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/a6959>
        rdf:type            wp:Stimulation , wp:Interaction , wp:DirectedInteraction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/18329679> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/a6959> ;
        wp:participants     <https://identifiers.org/ensembl/ENSG00000123104> , <https://identifiers.org/chebi/CHEBI:16595> ;
        wp:source           <https://identifiers.org/chebi/CHEBI:16595> ;
        wp:target           <https://identifiers.org/ensembl/ENSG00000123104> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/d2bcd>
        rdf:type            wp:DirectedInteraction , wp:Interaction , wp:Catalysis ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/20167242> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/d2bcd> ;
        wp:participants     <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/f3bf4> , <https://identifiers.org/ensembl/ENSG00000009765> ;
        wp:source           <https://identifiers.org/ensembl/ENSG00000009765> ;
        wp:target           <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/f3bf4> .

<https://identifiers.org/ensembl/ENSG00000077080>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "ACTL6B" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000077080> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000077080" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Complex/e9b9c> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/bcb57> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000077080> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/51412> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/ACTL6B> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/O94805> , <https://identifiers.org/uniprot/C9JQT4> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18040275> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/d1cc8> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/C9JQT4> , <http://purl.uniprot.org/uniprot/O94805> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000077080> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/db5ae>
        rdf:type            wp:DirectedInteraction , wp:Catalysis , wp:Interaction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/27351946> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/db5ae> ;
        wp:participants     <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/d0b9f> , <https://identifiers.org/ensembl/ENSG00000211452> ;
        wp:source           <https://identifiers.org/ensembl/ENSG00000211452> ;
        wp:target           <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/d0b9f> .

<https://identifiers.org/pubmed/20378719>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "20378719" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/ee727> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/fb9fe> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/f2651> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/a37c2> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/f4a25> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/ac99f> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/20378719> .

<https://identifiers.org/pubmed/20802499>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "20802499" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/c0740> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/c7250> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/20802499> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/ca42b>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4746_r140519> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/ca42b> ;
        wp:participants   <https://identifiers.org/chebi/CHEBI:16382> ;
        wp:source         <https://identifiers.org/chebi/CHEBI:16382> ;
        wp:target         <https://identifiers.org/chebi/CHEBI:16382> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/fd422>
        rdf:type            wp:Binding , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/25390014> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/fd422> ;
        wp:participants     <https://identifiers.org/kegg.pathway/map00020> , <https://identifiers.org/chebi/CHEBI:35366> ;
        wp:source           <https://identifiers.org/chebi/CHEBI:35366> ;
        wp:target           <https://identifiers.org/kegg.pathway/map00020> .

<https://identifiers.org/uniprot/P28482>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "ERK" ;
        dc:identifier       <https://identifiers.org/uniprot/P28482> ;
        dc:source           "UniProtKB" ;
        dcterms:identifier  "P28482" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/b7188> , <https://identifiers.org/wikipathways/WP4746_r140519> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/f55ab> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000100030> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/5594> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/MAPK1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/P28482> , <https://identifiers.org/uniprot/Q1HBJ4> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/f0ffd> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q1HBJ4> , <http://purl.uniprot.org/uniprot/P28482> ;
        foaf:page           <http://www.uniprot.org/uniprot/P28482> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/b0701>
        rdf:type            wp:DirectedInteraction , wp:Interaction , wp:Stimulation ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/18329679> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/b0701> ;
        wp:participants     <https://identifiers.org/ensembl/ENSG00000117020> , <https://identifiers.org/ensembl/ENSG00000135679> ;
        wp:source           <https://identifiers.org/ensembl/ENSG00000117020> ;
        wp:target           <https://identifiers.org/ensembl/ENSG00000135679> .

<https://identifiers.org/chebi/CHEBI:18332>
        rdf:type            wp:Metabolite , wp:DataNode ;
        rdfs:label          "T4" , "Albumin bound T4" , "TTR bound T4" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/XUIIKFGFIJCVMT-LBPRGKRZSA-N> ;
        dc:identifier       <https://identifiers.org/chebi/CHEBI:18332> ;
        dc:source           "ChEBI" ;
        dcterms:identifier  "CHEBI:18332" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/d0b9f> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/d9f9b> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/f3725> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/cbdc8> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/cf0e5> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/fea96> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/c6034> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/c3b2a> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/c29dc> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/b0cae> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/cee71> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/f0518> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/bf6ae> , <https://identifiers.org/wikipathways/WP4746_r140519> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:18332> , <https://identifiers.org/chebi/CHEBI:58448> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/5614> ;
        wp:bdbHmdb          <https://identifiers.org/hmdb/HMDB0000248> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/XUIIKFGFIJCVMT-LBPRGKRZSA-N> ;
        wp:bdbKeggCompound  <https://identifiers.org/kegg.compound/C01829> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID25201348> , <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID5819> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q106345689> , <http://www.wikidata.org/entity/Q773449> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/c8e84> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/fb541> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/ad90b> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/a6d8e> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/c8f03> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/e2be7> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/d62e1> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/fc367> ;
        foaf:page           <https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:18332> .

<https://identifiers.org/ensembl/ENSG00000139155>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "SLCO1C1" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000139155> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000139155" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/c6034> , <https://identifiers.org/wikipathways/WP4746_r140519> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/f0518> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000139155> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/53919> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/SLCO1C1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/F5H6S4> , <https://identifiers.org/uniprot/Q9NYB5> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18040736> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/b88ce> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q9NYB5> , <http://purl.uniprot.org/uniprot/F5H6S4> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000139155> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/dc852>
        rdf:type            wp:DirectedInteraction , wp:Binding , wp:Interaction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/23045339> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/dc852> ;
        wp:participants     <https://identifiers.org/chebi/CHEBI:18258> , <https://identifiers.org/ensembl/ENSG00000112394> ;
        wp:source           <https://identifiers.org/chebi/CHEBI:18258> ;
        wp:target           <https://identifiers.org/ensembl/ENSG00000112394> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/e0065>
        rdf:type            wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/19196800> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/e0065> ;
        wp:participants     <https://identifiers.org/chebi/CHEBI:16382> , <https://identifiers.org/ensembl/ENSG00000091137> ;
        wp:source           <https://identifiers.org/ensembl/ENSG00000091137> ;
        wp:target           <https://identifiers.org/chebi/CHEBI:16382> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/d9f9b>
        rdf:type            wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/29997323> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/d9f9b> ;
        wp:participants     <https://identifiers.org/chebi/CHEBI:18332> , <https://identifiers.org/chebi/CHEBI:75602> ;
        wp:source           <https://identifiers.org/chebi/CHEBI:75602> ;
        wp:target           <https://identifiers.org/chebi/CHEBI:18332> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/ComplexBinding/c8bdf>
        rdf:type          wp:ComplexBinding , wp:Binding , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4746_r140519> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Group/c8bdf> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000186350> , <https://identifiers.org/uniprot/P10827> , <https://identifiers.org/chebi/CHEBI:18258> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Complex/c8bdf> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/b15ce>
        rdf:type            wp:Inhibition , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/21440011> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/b15ce> ;
        wp:participants     <https://identifiers.org/ensembl/ENSG00000150907> , <https://identifiers.org/ensembl/ENSG00000117020> ;
        wp:source           <https://identifiers.org/ensembl/ENSG00000117020> ;
        wp:target           <https://identifiers.org/ensembl/ENSG00000150907> .

<https://identifiers.org/pubmed/23045339>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "23045339" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/dc852> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/be36b> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/23045339> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/a79b0>
        rdf:type            wp:DirectedInteraction , wp:Interaction , wp:Stimulation ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/11533250> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/a79b0> ;
        wp:participants     <https://identifiers.org/ensembl/ENSG00000168036> , <https://identifiers.org/ensembl/ENSG00000162552> ;
        wp:source           <https://identifiers.org/ensembl/ENSG00000168036> ;
        wp:target           <https://identifiers.org/ensembl/ENSG00000162552> .

<https://identifiers.org/ensembl/ENSG00000165269>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "AQP7" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000165269> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000165269" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/acb64> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000165269> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/364> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/AQP7> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q6P5T0> , <https://identifiers.org/uniprot/O14520> , <https://identifiers.org/uniprot/Q5T5M0> , <https://identifiers.org/uniprot/A0A096LNN5> , <https://identifiers.org/uniprot/Q5T5L3> , <https://identifiers.org/uniprot/Q5T5M1> , <https://identifiers.org/uniprot/A0A096LNK2> , <https://identifiers.org/uniprot/B7Z4U2> , <https://identifiers.org/uniprot/A0A096LP23> , <https://identifiers.org/uniprot/A0A096LNU3> , <https://identifiers.org/uniprot/A0A096LP64> , <https://identifiers.org/uniprot/A0A096LNV7> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q17831432> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/f673a> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A096LP23> , <http://purl.uniprot.org/uniprot/B7Z4U2> , <http://purl.uniprot.org/uniprot/A0A096LP64> , <http://purl.uniprot.org/uniprot/Q6P5T0> , <http://purl.uniprot.org/uniprot/A0A096LNU3> , <http://purl.uniprot.org/uniprot/A0A096LNK2> , <http://purl.uniprot.org/uniprot/A0A096LNN5> , <http://purl.uniprot.org/uniprot/Q5T5M1> , <http://purl.uniprot.org/uniprot/A0A096LNV7> , <http://purl.uniprot.org/uniprot/O14520> , <http://purl.uniprot.org/uniprot/Q5T5M0> , <http://purl.uniprot.org/uniprot/Q5T5L3> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000165269> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/c95ba>
        rdf:type            wp:DirectedInteraction , wp:Binding , wp:Interaction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/19196800> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/c95ba> ;
        wp:participants     <https://identifiers.org/ensembl/ENSG00000105641> , <https://identifiers.org/chebi/CHEBI:16382> ;
        wp:source           <https://identifiers.org/chebi/CHEBI:16382> ;
        wp:target           <https://identifiers.org/ensembl/ENSG00000105641> .

<https://identifiers.org/uniprot/G3V4Q4>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "ASK1" ;
        dc:identifier       <https://identifiers.org/uniprot/G3V4Q4> ;
        dc:source           "UniProtKB" ;
        dcterms:identifier  "G3V4Q4" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/d4ed4> , <https://identifiers.org/wikipathways/WP4746_r140519> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/d5821> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000012983> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/11183> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/MAP4K5> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/G3V5C6> , <https://identifiers.org/uniprot/G3V4T8> , <https://identifiers.org/uniprot/G3V4Q4> , <https://identifiers.org/uniprot/A0A804HIS2> , <https://identifiers.org/uniprot/Q9Y4K4> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/f21c6> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/G3V4Q4> , <http://purl.uniprot.org/uniprot/G3V4T8> , <http://purl.uniprot.org/uniprot/A0A804HIS2> , <http://purl.uniprot.org/uniprot/Q9Y4K4> , <http://purl.uniprot.org/uniprot/G3V5C6> ;
        foaf:page           <http://www.uniprot.org/uniprot/G3V4Q4> .

<https://identifiers.org/ensembl/ENSG00000074416>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "MGLL" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000074416> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000074416" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000074416> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/11343> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/MGLL> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/C9JAM4> , <https://identifiers.org/uniprot/H7C4E0> , <https://identifiers.org/uniprot/H7C5K5> , <https://identifiers.org/uniprot/A0A0C4DFN3> , <https://identifiers.org/uniprot/Q99685> , <https://identifiers.org/uniprot/A0A3B3ITT3> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18036488> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/e88cd> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A0C4DFN3> , <http://purl.uniprot.org/uniprot/A0A3B3ITT3> , <http://purl.uniprot.org/uniprot/C9JAM4> , <http://purl.uniprot.org/uniprot/Q99685> , <http://purl.uniprot.org/uniprot/H7C5K5> , <http://purl.uniprot.org/uniprot/H7C4E0> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000074416> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/d6efc>
        rdf:type            wp:DirectedInteraction , wp:Stimulation , wp:Interaction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/18329679> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/d6efc> ;
        wp:participants     <https://identifiers.org/chebi/CHEBI:16618> , <https://identifiers.org/ensembl/ENSG00000117020> ;
        wp:source           <https://identifiers.org/chebi/CHEBI:16618> ;
        wp:target           <https://identifiers.org/ensembl/ENSG00000117020> .

<https://identifiers.org/wikipathways/WP453>
        rdf:type            wp:Pathway , wp:DataNode ;
        rdfs:label          "Inflammation" ;
        dc:identifier       <https://identifiers.org/wikipathways/WP453> ;
        dc:source           "WikiPathways" ;
        dcterms:identifier  "WP453" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/bb638> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/c050d> ;
        foaf:page           <https://www.wikipathways.org/instance/WP453> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/Complex/e9b9c>
        rdf:type          wp:Complex , wp:DataNode ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4746_r140519> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Group/e9b9c> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000132170> , <https://identifiers.org/ensembl/ENSG00000077080> .

<https://identifiers.org/wikipathways/WP4746>
        pav:hasVersion  <https://identifiers.org/wikipathways/WP4746_r140519> .

<https://identifiers.org/ensembl/ENSG00000125482>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "TTF1" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000125482> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000125482" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/c586d> , <https://identifiers.org/wikipathways/WP4746_r140519> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Complex/e1401> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000125482> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/7270> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/TTF1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q15361> , <https://identifiers.org/uniprot/A0A024R8C1> , <https://identifiers.org/uniprot/A0A087WY09> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18032218> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/d3764> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A087WY09> , <http://purl.uniprot.org/uniprot/Q15361> , <http://purl.uniprot.org/uniprot/A0A024R8C1> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000125482> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/df053>
        rdf:type            wp:Interaction , wp:Stimulation , wp:DirectedInteraction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/18329679> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/df053> ;
        wp:participants     <https://identifiers.org/ensembl/ENSG00000121879> , <https://identifiers.org/chebi/CHEBI:16618> ;
        wp:source           <https://identifiers.org/ensembl/ENSG00000121879> ;
        wp:target           <https://identifiers.org/chebi/CHEBI:16618> .

<https://identifiers.org/chebi/CHEBI:16595>
        rdf:type            wp:Metabolite , wp:DataNode ;
        rdfs:label          "IP3" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/MMWCIQZXVOZEGG-XJTPDSDZSA-N> ;
        dc:identifier       <https://identifiers.org/chebi/CHEBI:16595> ;
        dc:source           "ChEBI" ;
        dcterms:identifier  "CHEBI:16595" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/d2708> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/fad79> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/a6959> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/eaf92> , <https://identifiers.org/wikipathways/WP4746_r140519> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:16595> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/388562> ;
        wp:bdbHmdb          <https://identifiers.org/hmdb/HMDB0001498> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/MMWCIQZXVOZEGG-XJTPDSDZSA-N> ;
        wp:bdbKeggCompound  <https://identifiers.org/kegg.compound/C01245> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID439456> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q26998374> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/b1952> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/f35f6> ;
        foaf:page           <https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:16595> .

<https://identifiers.org/ensembl/ENSG00000141510>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "P53" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000141510> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000141510" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/b8a42> , <https://identifiers.org/wikipathways/WP4746_r140519> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/f6278> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000141510> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/7157> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/TP53> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A087X1Q1> , <https://identifiers.org/uniprot/E7ESS1> , <https://identifiers.org/uniprot/H2EHT1> , <https://identifiers.org/uniprot/E9PFT5> , <https://identifiers.org/uniprot/A0A0U1RQC9> , <https://identifiers.org/uniprot/E9PCY9> , <https://identifiers.org/uniprot/I3L0W9> , <https://identifiers.org/uniprot/K7PPA8> , <https://identifiers.org/uniprot/J3KP33> , <https://identifiers.org/uniprot/S4R334> , <https://identifiers.org/uniprot/A0A087WXZ1> , <https://identifiers.org/uniprot/P04637> , <https://identifiers.org/uniprot/E7EMR6> , <https://identifiers.org/uniprot/A0A087WT22> , <https://identifiers.org/uniprot/E7EQX7> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q14818098> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/a2f85> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P04637> , <http://purl.uniprot.org/uniprot/E7EQX7> , <http://purl.uniprot.org/uniprot/E7EMR6> , <http://purl.uniprot.org/uniprot/E9PCY9> , <http://purl.uniprot.org/uniprot/E9PFT5> , <http://purl.uniprot.org/uniprot/K7PPA8> , <http://purl.uniprot.org/uniprot/S4R334> , <http://purl.uniprot.org/uniprot/A0A087WXZ1> , <http://purl.uniprot.org/uniprot/A0A087X1Q1> , <http://purl.uniprot.org/uniprot/I3L0W9> , <http://purl.uniprot.org/uniprot/A0A087WT22> , <http://purl.uniprot.org/uniprot/A0A0U1RQC9> , <http://purl.uniprot.org/uniprot/J3KP33> , <http://purl.uniprot.org/uniprot/E7ESS1> , <http://purl.uniprot.org/uniprot/H2EHT1> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000141510> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/fea96>
        rdf:type            wp:Binding , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/8222576> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/fea96> ;
        wp:participants     <https://identifiers.org/uniprot/P36021> , <https://identifiers.org/chebi/CHEBI:18332> ;
        wp:source           <https://identifiers.org/chebi/CHEBI:18332> ;
        wp:target           <https://identifiers.org/uniprot/P36021> .

<https://identifiers.org/uniprot/Q02750>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "MEK" ;
        dc:identifier       <https://identifiers.org/uniprot/Q02750> ;
        dc:source           "UniProtKB" ;
        dcterms:identifier  "Q02750" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/d9161> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/e4718> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/f55ab> , <https://identifiers.org/wikipathways/WP4746_r140519> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000169032> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/5604> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/MAP2K1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A8I5KRX5> , <https://identifiers.org/uniprot/A0A8I5KYB4> , <https://identifiers.org/uniprot/A4QPA9> , <https://identifiers.org/uniprot/A0A8I5QJP8> , <https://identifiers.org/uniprot/H3BRW9> , <https://identifiers.org/uniprot/A0A8I5KXN4> , <https://identifiers.org/uniprot/A0A8I5QJL9> , <https://identifiers.org/uniprot/A0A8I5QJC1> , <https://identifiers.org/uniprot/B4DFY5> , <https://identifiers.org/uniprot/A0A8I5QJ96> , <https://identifiers.org/uniprot/A0A8I5KVF6> , <https://identifiers.org/uniprot/A0A8I5KYS7> , <https://identifiers.org/uniprot/Q02750> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/b79bb> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A8I5KVF6> , <http://purl.uniprot.org/uniprot/A0A8I5KYS7> , <http://purl.uniprot.org/uniprot/A0A8I5KYB4> , <http://purl.uniprot.org/uniprot/A0A8I5QJP8> , <http://purl.uniprot.org/uniprot/A0A8I5QJ96> , <http://purl.uniprot.org/uniprot/A0A8I5QJL9> , <http://purl.uniprot.org/uniprot/A0A8I5KXN4> , <http://purl.uniprot.org/uniprot/Q02750> , <http://purl.uniprot.org/uniprot/H3BRW9> , <http://purl.uniprot.org/uniprot/A0A8I5QJC1> , <http://purl.uniprot.org/uniprot/A0A8I5KRX5> , <http://purl.uniprot.org/uniprot/A4QPA9> , <http://purl.uniprot.org/uniprot/B4DFY5> ;
        foaf:page           <http://www.uniprot.org/uniprot/Q02750> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/c658c>
        rdf:type            wp:DirectedInteraction , wp:Interaction , wp:Stimulation ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/18329679> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/c658c> ;
        wp:participants     <https://identifiers.org/uniprot/A0A087WT80> , <https://identifiers.org/chebi/CHEBI:18035> ;
        wp:source           <https://identifiers.org/uniprot/A0A087WT80> ;
        wp:target           <https://identifiers.org/chebi/CHEBI:18035> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/d4a02>
        rdf:type            wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/15971998> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/d4a02> ;
        wp:participants     <https://identifiers.org/kegg.pathway/hsa04931> , <https://identifiers.org/ensembl/ENSG00000136111> ;
        wp:source           <https://identifiers.org/ensembl/ENSG00000136111> ;
        wp:target           <https://identifiers.org/kegg.pathway/hsa04931> .

<https://identifiers.org/pubmed/15964803>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "15964803" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/af27e> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/d5821> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/d437f> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/f5893> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/ed87e> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/d4ed4> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/15964803> .

<https://identifiers.org/ensembl/ENSG00000166603>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "MC4R" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000166603> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000166603" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/b0d4d> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/eea5e> , <https://identifiers.org/wikipathways/WP4746_r140519> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000166603> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/4160> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/MC4R> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/P32245> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18028921> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/a62ca> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P32245> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000166603> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/fb9fe>
        rdf:type            wp:DirectedInteraction , wp:Stimulation , wp:Interaction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/20378719> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/fb9fe> ;
        wp:participants     <https://identifiers.org/uniprot/A0A087WT80> , <https://identifiers.org/ensembl/ENSG00000165409> ;
        wp:source           <https://identifiers.org/ensembl/ENSG00000165409> ;
        wp:target           <https://identifiers.org/uniprot/A0A087WT80> .

<https://identifiers.org/kegg.pathway/map00190>
        rdf:type            wp:Pathway , wp:DataNode ;
        rdfs:label          "Oxidative phosphorylation" ;
        dc:identifier       <https://identifiers.org/kegg.pathway/map00190> ;
        dc:source           "KEGG Pathway" ;
        dcterms:identifier  "map00190" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/b9e67> , <https://identifiers.org/wikipathways/WP4746_r140519> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/a4d61> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/cda31> ;
        foaf:page           <http://www.genome.jp/dbget-bin/www_bget?pathway+map00190> .

<https://identifiers.org/ensembl/ENSG00000091137>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "SLC26A4" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000091137> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000091137" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/e56cc> , <https://identifiers.org/wikipathways/WP4746_r140519> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/e0065> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000091137> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/5172> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/SLC26A4> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A2R8Y4W7> , <https://identifiers.org/uniprot/O43511> , <https://identifiers.org/uniprot/C9JQG1> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q14907462> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/af98a> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A2R8Y4W7> , <http://purl.uniprot.org/uniprot/C9JQG1> , <http://purl.uniprot.org/uniprot/O43511> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000091137> .

<https://identifiers.org/pubmed/17720805>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "17720805" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/bb9a8> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/ddc3d> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/17720805> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/c0740>
        rdf:type            wp:DirectedInteraction , wp:Interaction , wp:Inhibition ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/20802499> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/c0740> ;
        wp:participants     <https://identifiers.org/chebi/CHEBI:85053> , <https://identifiers.org/uniprot/P36021> ;
        wp:source           <https://identifiers.org/uniprot/P36021> ;
        wp:target           <https://identifiers.org/chebi/CHEBI:85053> .

<https://identifiers.org/pubmed/21448409>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "21448409" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/d2fd9> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/21448409> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/Complex/dddea>
        rdf:type          wp:Complex , wp:DataNode ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4746_r140519> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Group/dddea> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000122585> , <https://identifiers.org/ensembl/ENSG00000159723> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/Complex/c7580>
        rdf:type          wp:Complex , wp:DataNode ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4746_r140519> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Group/c7580> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000167965> , <https://identifiers.org/ensembl/ENSG00000198793> , <https://identifiers.org/ensembl/ENSG00000141564> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/d2fd9>
        rdf:type            wp:DirectedInteraction , wp:Stimulation , wp:Interaction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/21448409> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/d2fd9> ;
        wp:participants     <https://identifiers.org/ensembl/ENSG00000134200> , <https://identifiers.org/ensembl/ENSG00000165409> ;
        wp:source           <https://identifiers.org/ensembl/ENSG00000134200> ;
        wp:target           <https://identifiers.org/ensembl/ENSG00000165409> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/c4eff>
        rdf:type            wp:DirectedInteraction , wp:Stimulation , wp:Interaction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/27693079> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/c4eff> ;
        wp:participants     <https://identifiers.org/ensembl/ENSG00000109424> , <https://identifiers.org/ensembl/ENSG00000101493> ;
        wp:source           <https://identifiers.org/ensembl/ENSG00000101493> ;
        wp:target           <https://identifiers.org/ensembl/ENSG00000109424> .

<https://identifiers.org/chebi/CHEBI:16240>
        rdf:type            wp:DataNode , wp:Metabolite ;
        rdfs:label          "H2O2" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/MHAJPDPJQMAIIY-UHFFFAOYSA-N> ;
        dc:identifier       <https://identifiers.org/chebi/CHEBI:16240> ;
        dc:source           "ChEBI" ;
        dcterms:identifier  "CHEBI:16240" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/e3b59> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/bfaff> , <https://identifiers.org/wikipathways/WP4746_r140519> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:16240> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/763> ;
        wp:bdbHmdb          <https://identifiers.org/hmdb/HMDB0003125> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/MHAJPDPJQMAIIY-UHFFFAOYSA-N> ;
        wp:bdbKeggCompound  <https://identifiers.org/kegg.compound/C00027> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID784> , <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID22326046> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q171877> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/ac7ff> ;
        foaf:page           <https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:16240> .

<https://identifiers.org/ensembl/ENSG00000151090>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "THRB1" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000151090> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000151090" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/b820f> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Complex/dce5b> , <https://identifiers.org/wikipathways/WP4746_r140519> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Complex/f4317> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000151090> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/7068> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/THRB> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/C9JNQ4> , <https://identifiers.org/uniprot/C9JTN1> , <https://identifiers.org/uniprot/J3KR21> , <https://identifiers.org/uniprot/A0A024R2I8> , <https://identifiers.org/uniprot/C9JZS5> , <https://identifiers.org/uniprot/C9JHC2> , <https://identifiers.org/uniprot/A0A2R8YF24> , <https://identifiers.org/uniprot/P10828> , <https://identifiers.org/uniprot/A0A0C4DG57> , <https://identifiers.org/uniprot/C9JJM3> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18031987> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/c23d8> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/e1422> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P10828> , <http://purl.uniprot.org/uniprot/C9JZS5> , <http://purl.uniprot.org/uniprot/C9JNQ4> , <http://purl.uniprot.org/uniprot/A0A024R2I8> , <http://purl.uniprot.org/uniprot/A0A0C4DG57> , <http://purl.uniprot.org/uniprot/A0A2R8YF24> , <http://purl.uniprot.org/uniprot/C9JTN1> , <http://purl.uniprot.org/uniprot/C9JJM3> , <http://purl.uniprot.org/uniprot/C9JHC2> , <http://purl.uniprot.org/uniprot/J3KR21> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000151090> .

<https://identifiers.org/uniprot/A0A087X094>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "ANP" ;
        dc:identifier       <https://identifiers.org/uniprot/A0A087X094> ;
        dc:source           "UniProtKB" ;
        dcterms:identifier  "A0A087X094" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/e3c81> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A087X094> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/d524f> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A087X094> ;
        foaf:page           <http://www.uniprot.org/uniprot/A0A087X094> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/bb638>
        rdf:type            wp:Stimulation , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/22353746> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/bb638> ;
        wp:participants     <https://identifiers.org/ensembl/ENSG00000211448> , <https://identifiers.org/wikipathways/WP453> ;
        wp:source           <https://identifiers.org/wikipathways/WP453> ;
        wp:target           <https://identifiers.org/ensembl/ENSG00000211448> .

<https://identifiers.org/ensembl/ENSG00000141564>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "RAPTOR" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000141564> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000141564" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Complex/c7580> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000141564> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/57521> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/RPTOR> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A8V8TMD9> , <https://identifiers.org/uniprot/I3L2I3> , <https://identifiers.org/uniprot/I3L436> , <https://identifiers.org/uniprot/Q8N122> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18043110> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/ea219> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q8N122> , <http://purl.uniprot.org/uniprot/I3L2I3> , <http://purl.uniprot.org/uniprot/I3L436> , <http://purl.uniprot.org/uniprot/A0A8V8TMD9> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000141564> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/cae86>
        rdf:type            wp:Catalysis , wp:Interaction , wp:DirectedInteraction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/27351946> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/cae86> ;
        wp:participants     <https://identifiers.org/ensembl/ENSG00000211448> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/d0b9f> ;
        wp:source           <https://identifiers.org/ensembl/ENSG00000211448> ;
        wp:target           <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/d0b9f> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/ComplexBinding/c5ef2>
        rdf:type          wp:ComplexBinding , wp:Binding , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4746_r140519> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Group/c5ef2> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000140279> , <https://identifiers.org/ensembl/ENSG00000140274> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Complex/c5ef2> .

<https://identifiers.org/uniprot/P16860>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "BNP" ;
        dc:identifier       <https://identifiers.org/uniprot/P16860> ;
        dc:source           "UniProtKB" ;
        dcterms:identifier  "P16860" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/e02af> , <https://identifiers.org/wikipathways/WP4746_r140519> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000120937> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/4879> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/NPPB> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/P16860> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/f3c11> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P16860> ;
        foaf:page           <http://www.uniprot.org/uniprot/P16860> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/a744d>
        rdf:type            wp:DirectedInteraction , wp:Stimulation , wp:Interaction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/16428285> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/a744d> ;
        wp:participants     <https://identifiers.org/uniprot/Q15136> , <https://identifiers.org/ensembl/ENSG00000116830> ;
        wp:source           <https://identifiers.org/uniprot/Q15136> ;
        wp:target           <https://identifiers.org/ensembl/ENSG00000116830> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/ComplexBinding/e1401>
        rdf:type          wp:ComplexBinding , wp:Binding , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4746_r140519> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Group/e1401> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000116830> , <https://identifiers.org/ensembl/ENSG00000125482> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Complex/e1401> .

<https://identifiers.org/ensembl/ENSG00000123836>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "PFKFB2" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000123836> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000123836" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/aad88> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/e1b11> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000123836> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/5208> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/PFKFB2> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A087X2H4> , <https://identifiers.org/uniprot/F6RAZ1> , <https://identifiers.org/uniprot/F6XNB3> , <https://identifiers.org/uniprot/A0A087X278> , <https://identifiers.org/uniprot/O60825> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18030481> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/a4ded> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/F6XNB3> , <http://purl.uniprot.org/uniprot/A0A087X2H4> , <http://purl.uniprot.org/uniprot/A0A087X278> , <http://purl.uniprot.org/uniprot/F6RAZ1> , <http://purl.uniprot.org/uniprot/O60825> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000123836> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/c3b2a>
        rdf:type          wp:Conversion , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4746_r140519> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/c3b2a> ;
        wp:participants   <https://identifiers.org/chebi/CHEBI:18258> , <https://identifiers.org/chebi/CHEBI:18332> ;
        wp:source         <https://identifiers.org/chebi/CHEBI:18332> ;
        wp:target         <https://identifiers.org/chebi/CHEBI:18258> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/c5d51>
        rdf:type            wp:DirectedInteraction , wp:Interaction , wp:Stimulation ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/24872083> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/c5d51> ;
        wp:participants     <https://identifiers.org/ensembl/ENSG00000166819> , <https://identifiers.org/uniprot/A0A140VJM3> ;
        wp:source           <https://identifiers.org/uniprot/A0A140VJM3> ;
        wp:target           <https://identifiers.org/ensembl/ENSG00000166819> .

<https://identifiers.org/ensembl/ENSG00000140279>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "DUOX2" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000140279> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000140279" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Complex/c5ef2> , <https://identifiers.org/wikipathways/WP4746_r140519> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/a8e9e> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/bd79b> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000140279> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/50506> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/DUOX2> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/X6RAN8> , <https://identifiers.org/uniprot/Q9NRD8> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18039811> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/fb990> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q9NRD8> , <http://purl.uniprot.org/uniprot/X6RAN8> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000140279> .

<https://identifiers.org/ensembl/ENSG00000170893>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "TRH" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000170893> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000170893" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000170893> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/7200> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/TRH> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/D6RFM1> , <https://identifiers.org/uniprot/P20396> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18032104> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/f7648> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/D6RFM1> , <http://purl.uniprot.org/uniprot/P20396> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000170893> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/da923>
        rdf:type          wp:Stimulation , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4746_r140519> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/da923> ;
        wp:participants   <https://identifiers.org/uniprot/Q7LBC6> , <https://identifiers.org/uniprot/Q15136> ;
        wp:source         <https://identifiers.org/uniprot/Q15136> ;
        wp:target         <https://identifiers.org/uniprot/Q7LBC6> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/f6278>
        rdf:type            wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/18329679> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/f6278> ;
        wp:participants     <https://identifiers.org/wikipathways/WP3804> , <https://identifiers.org/ensembl/ENSG00000141510> ;
        wp:source           <https://identifiers.org/ensembl/ENSG00000141510> ;
        wp:target           <https://identifiers.org/wikipathways/WP3804> .

<https://identifiers.org/pubmed/12172553>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "12172553" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/e8b0f> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/dda4f> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/b4f20> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/d0f36> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q28131740> ;
        owl:sameAs          <https://doi.org/10.1038%2FNCB839> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/12172553> .

<https://identifiers.org/kegg.pathway/hsa04211>
        rdf:type            wp:DataNode , wp:Pathway ;
        rdfs:label          "Cell survival" ;
        dc:identifier       <https://identifiers.org/kegg.pathway/hsa04211> ;
        dc:source           "KEGG Pathway" ;
        dcterms:identifier  "hsa04211" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/dc595> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/ae922> , <https://identifiers.org/wikipathways/WP4746_r140519> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/c65ca> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/a71bb> ;
        foaf:page           <http://www.genome.jp/dbget-bin/www_bget?pathway+hsa04211> .

<https://identifiers.org/pubmed/24820868>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "24820868" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/e02af> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/e3c81> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/ebd53> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/ef13e> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/ebd7b> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/24820868> .

<https://identifiers.org/ensembl/ENSG00000101493>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "ZNF516" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000101493> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000101493" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/c4eff> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Complex/ae4e2> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000101493> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/9658> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/ZNF516> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/H0YH41> , <https://identifiers.org/uniprot/Q92618> , <https://identifiers.org/uniprot/F5H2K2> , <https://identifiers.org/uniprot/A0A087WUJ4> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18034559> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/a1168> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q92618> , <http://purl.uniprot.org/uniprot/A0A087WUJ4> , <http://purl.uniprot.org/uniprot/F5H2K2> , <http://purl.uniprot.org/uniprot/H0YH41> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000101493> .

<https://identifiers.org/pubmed/17574010>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "17574010" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/d68fa> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/c6034> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/d1c5b> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/b9e72> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/f0518> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/b7bb2> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/be8be> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/e64a3> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/17574010> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/fc91b>
        rdf:type            wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/20167242> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/fc91b> ;
        wp:participants     <https://identifiers.org/uniprot/E5RG33> ;
        wp:source           <https://identifiers.org/uniprot/E5RG33> ;
        wp:target           <https://identifiers.org/uniprot/E5RG33> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/c194f>
        rdf:type            wp:Interaction , wp:DirectedInteraction , wp:Stimulation ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/18329679> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/c194f> ;
        wp:participants     <https://identifiers.org/ensembl/ENSG00000123104> , <https://identifiers.org/chebi/CHEBI:29108> ;
        wp:source           <https://identifiers.org/ensembl/ENSG00000123104> ;
        wp:target           <https://identifiers.org/chebi/CHEBI:29108> .

<https://identifiers.org/ensembl/ENSG00000136111>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "AS160" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000136111> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000136111" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/e157f> , <https://identifiers.org/wikipathways/WP4746_r140519> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/d4a02> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000136111> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/9882> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/TBC1D4> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q5JU47> , <https://identifiers.org/uniprot/O60343> , <https://identifiers.org/uniprot/A0A3B3IRT3> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18034838> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/ca8db> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q5JU47> , <http://purl.uniprot.org/uniprot/A0A3B3IRT3> , <http://purl.uniprot.org/uniprot/O60343> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000136111> .

<https://identifiers.org/pubmed/19196800>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "19196800" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/b1649> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/e56cc> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/c95ba> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/e0065> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/19196800> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/Complex/dce5b>
        rdf:type          wp:Complex , wp:DataNode ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4746_r140519> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Group/dce5b> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000186350> , <https://identifiers.org/chebi/CHEBI:18258> , <https://identifiers.org/ensembl/ENSG00000151090> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/fa968>
        rdf:type            wp:Interaction , wp:DirectedInteraction , wp:Binding ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/29997323> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/fa968> ;
        wp:participants     <https://identifiers.org/uniprot/P36021> , <https://identifiers.org/chebi/CHEBI:18258> ;
        wp:source           <https://identifiers.org/chebi/CHEBI:18258> ;
        wp:target           <https://identifiers.org/uniprot/P36021> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/c8f3a>
        rdf:type            wp:Inhibition , wp:Interaction , wp:DirectedInteraction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/18467435> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/c8f3a> ;
        wp:participants     <https://identifiers.org/ensembl/ENSG00000168036> , <https://identifiers.org/ensembl/ENSG00000082701> ;
        wp:source           <https://identifiers.org/ensembl/ENSG00000082701> ;
        wp:target           <https://identifiers.org/ensembl/ENSG00000168036> .

<https://identifiers.org/chebi/CHEBI:17754>
        rdf:type            wp:DataNode , wp:Metabolite ;
        rdfs:label          "Glycerol" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/PEDCQBHIVMGVHV-UHFFFAOYSA-N> ;
        dc:identifier       <https://identifiers.org/chebi/CHEBI:17754> ;
        dc:source           "ChEBI" ;
        dcterms:identifier  "CHEBI:17754" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/acb64> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:17754> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/733> ;
        wp:bdbHmdb          <https://identifiers.org/hmdb/HMDB0000131> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/PEDCQBHIVMGVHV-UHFFFAOYSA-N> ;
        wp:bdbKeggCompound  <https://identifiers.org/kegg.compound/C00116> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID753> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q132501> , <http://www.wikidata.org/entity/Q72501434> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/c604f> ;
        foaf:page           <https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:17754> .

<https://identifiers.org/kegg.pathway/map04310>
        rdf:type            wp:DataNode , wp:Pathway ;
        rdfs:label          "Wnt signaling" ;
        dc:identifier       <https://identifiers.org/kegg.pathway/map04310> ;
        dc:source           "KEGG Pathway" ;
        dcterms:identifier  "map04310" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/a742d> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/e562a> ;
        foaf:page           <http://www.genome.jp/dbget-bin/www_bget?pathway+map04310> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/f5893>
        rdf:type            wp:Stimulation , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/15964803> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/f5893> ;
        wp:participants     <https://identifiers.org/uniprot/Q16539> , <https://identifiers.org/uniprot/A0A024R2W7> ;
        wp:source           <https://identifiers.org/uniprot/A0A024R2W7> ;
        wp:target           <https://identifiers.org/uniprot/Q16539> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/e90a1>
        rdf:type          wp:Stimulation , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4746_r140519> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/e90a1> ;
        wp:participants   <https://identifiers.org/kegg.pathway/map04150> , <https://identifiers.org/uniprot/P36021> ;
        wp:source         <https://identifiers.org/uniprot/P36021> ;
        wp:target         <https://identifiers.org/kegg.pathway/map04150> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/Complex/b6566>
        rdf:type          wp:Complex , wp:DataNode ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4746_r140519> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Group/b6566> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000259207> , <https://identifiers.org/ensembl/ENSG00000138448> .

<https://identifiers.org/ensembl/ENSG00000137154>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "S6" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000137154> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000137154" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/d5383> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/b68fc> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/a3ac8> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000137154> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/6194> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/RPS6> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A2A3R5> , <https://identifiers.org/uniprot/P62753> , <https://identifiers.org/uniprot/A2A3R6> , <https://identifiers.org/uniprot/A2A3R7> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q7322419> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/fa037> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A2A3R5> , <http://purl.uniprot.org/uniprot/A2A3R7> , <http://purl.uniprot.org/uniprot/A2A3R6> , <http://purl.uniprot.org/uniprot/P62753> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000137154> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/Complex/de5d5>
        rdf:type          wp:Complex , wp:DataNode ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4746_r140519> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Group/de5d5> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000126351> , <https://identifiers.org/chebi/CHEBI:18258> .

<https://identifiers.org/ensembl/ENSG00000165409>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "TSHR" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000165409> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000165409" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/f2651> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/d2fd9> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/fb9fe> , <https://identifiers.org/wikipathways/WP4746_r140519> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000165409> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/7253> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/TSHR> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q0VAP8> , <https://identifiers.org/uniprot/A0A1B0GUJ5> , <https://identifiers.org/uniprot/A0A0A0MTJ0> , <https://identifiers.org/uniprot/G3V381> , <https://identifiers.org/uniprot/P16473> , <https://identifiers.org/uniprot/A0A2R8Y709> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q14904941> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/cf03d> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/G3V381> , <http://purl.uniprot.org/uniprot/P16473> , <http://purl.uniprot.org/uniprot/A0A0A0MTJ0> , <http://purl.uniprot.org/uniprot/A0A2R8Y709> , <http://purl.uniprot.org/uniprot/A0A1B0GUJ5> , <http://purl.uniprot.org/uniprot/Q0VAP8> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000165409> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/Complex/f4317>
        rdf:type          wp:Complex , wp:DataNode ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4746_r140519> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Group/f4317> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000151090> , <https://identifiers.org/chebi/CHEBI:18258> .

<https://identifiers.org/pubmed/27693079>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "27693079" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/c4eff> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/bcb57> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/af4ed> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/27693079> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/b6ec1>
        rdf:type            wp:Interaction , wp:DirectedInteraction , wp:Stimulation ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/25390014> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/b6ec1> ;
        wp:participants     <https://identifiers.org/chebi/CHEBI:35366> , <https://identifiers.org/ensembl/ENSG00000109424> ;
        wp:source           <https://identifiers.org/chebi/CHEBI:35366> ;
        wp:target           <https://identifiers.org/ensembl/ENSG00000109424> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/Complex/b8acc>
        rdf:type          wp:Complex , wp:DataNode ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4746_r140519> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Group/b8acc> ;
        wp:participants   <https://identifiers.org/chebi/CHEBI:29264> , <https://identifiers.org/ensembl/ENSG00000138593> .

<https://identifiers.org/pubmed/17452290>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "17452290" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/b8bdc> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/17452290> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/bd79b>
        rdf:type            wp:Interaction , wp:Stimulation , wp:DirectedInteraction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/21683758> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/bd79b> ;
        wp:participants     <https://identifiers.org/ensembl/ENSG00000140279> , <https://identifiers.org/uniprot/A0A087X0I9> ;
        wp:source           <https://identifiers.org/uniprot/A0A087X0I9> ;
        wp:target           <https://identifiers.org/ensembl/ENSG00000140279> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/Complex/d5116>
        rdf:type          wp:Complex , wp:DataNode ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4746_r140519> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Group/d5116> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000165699> , <https://identifiers.org/ensembl/ENSG00000103197> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/d6ae8>
        rdf:type            wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/29997323> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/d6ae8> ;
        wp:participants     <https://identifiers.org/chebi/CHEBI:18258> ;
        wp:source           <https://identifiers.org/chebi/CHEBI:18258> ;
        wp:target           <https://identifiers.org/chebi/CHEBI:18258> .

<https://identifiers.org/ensembl/ENSG00000140274>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "DUOXA2" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000140274> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000140274" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Complex/c5ef2> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000140274> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/405753> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/DUOXA2> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q1HG44> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18057992> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/ae19c> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q1HG44> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000140274> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/beb87>
        rdf:type            wp:Stimulation , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/24872083> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/beb87> ;
        wp:participants     <https://identifiers.org/uniprot/Q15136> , <https://identifiers.org/ensembl/ENSG00000166819> ;
        wp:source           <https://identifiers.org/uniprot/Q15136> ;
        wp:target           <https://identifiers.org/ensembl/ENSG00000166819> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/dda4f>
        rdf:type            wp:Interaction , wp:Stimulation , wp:DirectedInteraction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/12172553> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/dda4f> ;
        wp:participants     <https://identifiers.org/ensembl/ENSG00000198793> , <https://identifiers.org/ensembl/ENSG00000106615> ;
        wp:source           <https://identifiers.org/ensembl/ENSG00000106615> ;
        wp:target           <https://identifiers.org/ensembl/ENSG00000198793> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/c65ca>
        rdf:type            wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/21440011> , <https://identifiers.org/pubmed/9346240> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/c65ca> ;
        wp:participants     <https://identifiers.org/kegg.pathway/hsa04211> , <https://identifiers.org/ensembl/ENSG00000150907> ;
        wp:source           <https://identifiers.org/ensembl/ENSG00000150907> ;
        wp:target           <https://identifiers.org/kegg.pathway/hsa04211> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/e4011>
        rdf:type            wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/29997323> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/e4011> ;
        wp:participants     <https://identifiers.org/chebi/CHEBI:18258> ;
        wp:source           <https://identifiers.org/chebi/CHEBI:18258> ;
        wp:target           <https://identifiers.org/chebi/CHEBI:18258> .

<https://identifiers.org/ensembl/ENSG00000109424>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "UCP1" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000109424> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000109424" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/af4ed> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/c4eff> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/b6ec1> , <https://identifiers.org/wikipathways/WP4746_r140519> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/a1f30> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/b68fc> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/d0a5e> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/cde4d> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/cdb14> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000109424> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/7350> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/UCP1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/P25874> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q14860933> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/f291d> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/fb07f> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P25874> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000109424> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/d4ed4>
        rdf:type            wp:Interaction , wp:Stimulation , wp:DirectedInteraction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/15964803> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/d4ed4> ;
        wp:participants     <https://identifiers.org/uniprot/A0A024R2W7> , <https://identifiers.org/uniprot/G3V4Q4> ;
        wp:source           <https://identifiers.org/uniprot/G3V4Q4> ;
        wp:target           <https://identifiers.org/uniprot/A0A024R2W7> .

<https://identifiers.org/ensembl/ENSG00000211452>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "DIO1" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000211452> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000211452" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/db5ae> , <https://identifiers.org/wikipathways/WP4746_r140519> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000211452> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/1733> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/DIO1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/E9PM07> , <https://identifiers.org/uniprot/C6ZRC2> , <https://identifiers.org/uniprot/F6RP93> , <https://identifiers.org/uniprot/E9PI35> , <https://identifiers.org/uniprot/A0A182DWI2> , <https://identifiers.org/uniprot/P49895> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q17914000> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/aae3f> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P49895> , <http://purl.uniprot.org/uniprot/E9PM07> , <http://purl.uniprot.org/uniprot/A0A182DWI2> , <http://purl.uniprot.org/uniprot/F6RP93> , <http://purl.uniprot.org/uniprot/E9PI35> , <http://purl.uniprot.org/uniprot/C6ZRC2> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000211452> .

<https://identifiers.org/ensembl/ENSG00000182759>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "MAFA" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000182759> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000182759" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000182759> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/389692> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/MAFA> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q8NHW3> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18056700> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/a63b2> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q8NHW3> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000182759> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/cbdc8>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4746_r140519> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/cbdc8> ;
        wp:participants   <https://identifiers.org/chebi/CHEBI:18332> , <https://identifiers.org/uniprot/P36021> ;
        wp:source         <https://identifiers.org/uniprot/P36021> ;
        wp:target         <https://identifiers.org/chebi/CHEBI:18332> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/Complex/a0028>
        rdf:type          wp:Complex , wp:DataNode ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4746_r140519> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Group/a0028> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000259207> , <https://identifiers.org/ensembl/ENSG00000138448> .

<https://identifiers.org/ensembl/ENSG00000134200>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "TSH" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000134200> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000134200" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/d2fd9> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000134200> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/7252> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/TSHB> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/P01222> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18032201> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/a443a> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P01222> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000134200> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/e64f6>
        rdf:type            wp:Interaction , wp:Stimulation , wp:DirectedInteraction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/21317437> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/e64f6> ;
        wp:participants     <https://identifiers.org/ensembl/ENSG00000115966> , <https://identifiers.org/uniprot/Q16539> ;
        wp:source           <https://identifiers.org/uniprot/Q16539> ;
        wp:target           <https://identifiers.org/ensembl/ENSG00000115966> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/ComplexBinding/c7580>
        rdf:type          wp:ComplexBinding , wp:Binding , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4746_r140519> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Group/c7580> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000167965> , <https://identifiers.org/ensembl/ENSG00000198793> , <https://identifiers.org/ensembl/ENSG00000141564> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Complex/c7580> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/ComplexBinding/dddea>
        rdf:type          wp:ComplexBinding , wp:Binding , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4746_r140519> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Group/dddea> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000122585> , <https://identifiers.org/ensembl/ENSG00000159723> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Complex/dddea> .

<https://doi.org/10.1042%2FBJ20050887>
        dc:source           "DOI" ;
        dcterms:identifier  "10.1042/BJ20050887" .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/a4d61>
        rdf:type            wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/25390014> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/a4d61> ;
        wp:participants     <https://identifiers.org/chebi/CHEBI:15378> , <https://identifiers.org/kegg.pathway/map00190> ;
        wp:source           <https://identifiers.org/kegg.pathway/map00190> ;
        wp:target           <https://identifiers.org/chebi/CHEBI:15378> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/e8b0f>
        rdf:type            wp:Inhibition , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/12172553> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/e8b0f> ;
        wp:participants     <https://identifiers.org/ensembl/ENSG00000103197> , <https://identifiers.org/ensembl/ENSG00000117020> ;
        wp:source           <https://identifiers.org/ensembl/ENSG00000117020> ;
        wp:target           <https://identifiers.org/ensembl/ENSG00000103197> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/a5b51>
        rdf:type            wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/20167242> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/a5b51> ;
        wp:participants     <https://identifiers.org/chebi/CHEBI:23796> , <https://identifiers.org/uniprot/E5RG33> ;
        wp:source           <https://identifiers.org/uniprot/E5RG33> ;
        wp:target           <https://identifiers.org/chebi/CHEBI:23796> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/e3b59>
        rdf:type          wp:Binding , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4746_r140519> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/e3b59> ;
        wp:participants   <https://identifiers.org/uniprot/E5RG33> , <https://identifiers.org/chebi/CHEBI:16240> ;
        wp:source         <https://identifiers.org/chebi/CHEBI:16240> ;
        wp:target         <https://identifiers.org/uniprot/E5RG33> .

<https://identifiers.org/ensembl/ENSG00000132155>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "RAF1" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000132155> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000132155" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/d9161> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/cb62d> , <https://identifiers.org/wikipathways/WP4746_r140519> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000132155> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/5894> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/RAF1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A8I5KSM4> , <https://identifiers.org/uniprot/A0A8I5KWS9> , <https://identifiers.org/uniprot/A0A8I5KQV4> , <https://identifiers.org/uniprot/A0A8I5KSB0> , <https://identifiers.org/uniprot/A0A8I5KTK4> , <https://identifiers.org/uniprot/A0A8I5KSV6> , <https://identifiers.org/uniprot/P04049> , <https://identifiers.org/uniprot/H7C155> , <https://identifiers.org/uniprot/A0A8I5KYC4> , <https://identifiers.org/uniprot/A0A8I5KR46> , <https://identifiers.org/uniprot/A0A8I5KWA9> , <https://identifiers.org/uniprot/A0A8I5QJG5> , <https://identifiers.org/uniprot/A0A8I5KS16> , <https://identifiers.org/uniprot/A0A8I5KSI1> , <https://identifiers.org/uniprot/A0A8I5KTA5> , <https://identifiers.org/uniprot/A0A0B4J1W9> , <https://identifiers.org/uniprot/A0A8I5QKZ6> , <https://identifiers.org/uniprot/A0A8I5KW44> , <https://identifiers.org/uniprot/A0A8I5KRD1> , <https://identifiers.org/uniprot/A0A8I5QKU8> , <https://identifiers.org/uniprot/L7RRS6> , <https://identifiers.org/uniprot/A0A8I5KQ33> , <https://identifiers.org/uniprot/A0A0S2Z559> , <https://identifiers.org/uniprot/A0A8I5KYP5> , <https://identifiers.org/uniprot/A0A8I5KWF7> , <https://identifiers.org/uniprot/A0A8I5KUW4> , <https://identifiers.org/uniprot/A0A8I5KT32> , <https://identifiers.org/uniprot/A0A8I5KX50> , <https://identifiers.org/uniprot/A0A0S2Z4L5> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q14903573> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/bfecd> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A8I5KTK4> , <http://purl.uniprot.org/uniprot/A0A8I5KQ33> , <http://purl.uniprot.org/uniprot/A0A8I5QKZ6> , <http://purl.uniprot.org/uniprot/A0A8I5KYP5> , <http://purl.uniprot.org/uniprot/H7C155> , <http://purl.uniprot.org/uniprot/A0A8I5KSI1> , <http://purl.uniprot.org/uniprot/A0A8I5KWA9> , <http://purl.uniprot.org/uniprot/A0A0S2Z559> , <http://purl.uniprot.org/uniprot/A0A8I5KSM4> , <http://purl.uniprot.org/uniprot/A0A8I5KSV6> , <http://purl.uniprot.org/uniprot/A0A8I5KWF7> , <http://purl.uniprot.org/uniprot/A0A8I5KUW4> , <http://purl.uniprot.org/uniprot/A0A8I5QJG5> , <http://purl.uniprot.org/uniprot/A0A0S2Z4L5> , <http://purl.uniprot.org/uniprot/A0A0B4J1W9> , <http://purl.uniprot.org/uniprot/L7RRS6> , <http://purl.uniprot.org/uniprot/A0A8I5KYC4> , <http://purl.uniprot.org/uniprot/A0A8I5KS16> , <http://purl.uniprot.org/uniprot/P04049> , <http://purl.uniprot.org/uniprot/A0A8I5KTA5> , <http://purl.uniprot.org/uniprot/A0A8I5KRD1> , <http://purl.uniprot.org/uniprot/A0A8I5KT32> , <http://purl.uniprot.org/uniprot/A0A8I5QKU8> , <http://purl.uniprot.org/uniprot/A0A8I5KWS9> , <http://purl.uniprot.org/uniprot/A0A8I5KSB0> , <http://purl.uniprot.org/uniprot/A0A8I5KR46> , <http://purl.uniprot.org/uniprot/A0A8I5KX50> , <http://purl.uniprot.org/uniprot/A0A8I5KW44> , <http://purl.uniprot.org/uniprot/A0A8I5KQV4> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000132155> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/c6034>
        rdf:type            wp:DirectedInteraction , wp:Interaction , wp:Binding ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/17574010> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/c6034> ;
        wp:participants     <https://identifiers.org/ensembl/ENSG00000139155> , <https://identifiers.org/chebi/CHEBI:18332> ;
        wp:source           <https://identifiers.org/chebi/CHEBI:18332> ;
        wp:target           <https://identifiers.org/ensembl/ENSG00000139155> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/ef13e>
        rdf:type            wp:Stimulation , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/24820868> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/ef13e> ;
        wp:participants     <https://identifiers.org/chebi/CHEBI:16356> , <https://identifiers.org/uniprot/P16066> ;
        wp:source           <https://identifiers.org/uniprot/P16066> ;
        wp:target           <https://identifiers.org/chebi/CHEBI:16356> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/Complex/ee028>
        rdf:type          wp:Complex , wp:DataNode ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4746_r140519> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Group/ee028> ;
        wp:participants   <https://identifiers.org/uniprot/P10827> , <https://identifiers.org/chebi/CHEBI:18258> , <https://identifiers.org/ensembl/ENSG00000186350> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/c29dc>
        rdf:type            wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/20167242> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/c29dc> ;
        wp:participants     <https://identifiers.org/chebi/CHEBI:18332> , <https://identifiers.org/uniprot/E5RG33> ;
        wp:source           <https://identifiers.org/uniprot/E5RG33> ;
        wp:target           <https://identifiers.org/chebi/CHEBI:18332> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/ded54>
        rdf:type            wp:Binding , wp:Interaction , wp:DirectedInteraction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/22653837> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/ded54> ;
        wp:participants     <https://identifiers.org/chebi/CHEBI:17489> , <https://identifiers.org/uniprot/Q15136> ;
        wp:source           <https://identifiers.org/chebi/CHEBI:17489> ;
        wp:target           <https://identifiers.org/uniprot/Q15136> .

<https://identifiers.org/wikipathways/WP3318>
        rdf:type            wp:Pathway , wp:DataNode ;
        rdfs:label          "mTOR" , "Cell growth, proliferation and protein synthesis" ;
        dc:identifier       <https://identifiers.org/wikipathways/WP3318> ;
        dc:source           "WikiPathways" ;
        dcterms:identifier  "WP3318" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/b4f20> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/d521a> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/f2dae> ;
        foaf:page           <https://www.wikipathways.org/instance/WP3318> .

<https://identifiers.org/chebi/CHEBI:15378>
        rdf:type            wp:Metabolite , wp:DataNode ;
        rdfs:label          "H⁺" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/GPRLSGONYQIRFK-UHFFFAOYSA-N> ;
        dc:identifier       <https://identifiers.org/chebi/CHEBI:15378> ;
        dc:source           "ChEBI" ;
        dcterms:identifier  "CHEBI:15378" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/cdb14> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/a4d61> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/a1f30> , <https://identifiers.org/wikipathways/WP4746_r140519> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:15378> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/1010> ;
        wp:bdbHmdb          <https://identifiers.org/hmdb/HMDB0059597> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/GPRLSGONYQIRFK-UHFFFAOYSA-N> ;
        wp:bdbKeggCompound  <https://identifiers.org/kegg.compound/C00080> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID1038> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q506710> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/d4b5d> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/faa2e> ;
        foaf:page           <https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:15378> .

<https://identifiers.org/pubmed/16428285>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "16428285" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/a744d> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/16428285> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/cde4d>
        rdf:type            wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/25390014> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/cde4d> ;
        wp:participants     <https://identifiers.org/ensembl/ENSG00000109424> ;
        wp:source           <https://identifiers.org/ensembl/ENSG00000109424> ;
        wp:target           <https://identifiers.org/ensembl/ENSG00000109424> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/b0cae>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4746_r140519> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/b0cae> ;
        wp:participants   <https://identifiers.org/chebi/CHEBI:18332> ;
        wp:source         <https://identifiers.org/chebi/CHEBI:18332> ;
        wp:target         <https://identifiers.org/chebi/CHEBI:18332> .

<https://identifiers.org/ensembl/ENSG00000165699>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "TSC1" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000165699> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000165699" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Complex/d5116> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000165699> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/7248> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/TSC1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A2R8Y419> , <https://identifiers.org/uniprot/A0A2R8Y5U8> , <https://identifiers.org/uniprot/A0A2R8Y6W1> , <https://identifiers.org/uniprot/A0A2R8Y756> , <https://identifiers.org/uniprot/A0A2R8Y6T5> , <https://identifiers.org/uniprot/A0A2R8Y5F8> , <https://identifiers.org/uniprot/A0A2R8Y6S8> , <https://identifiers.org/uniprot/A0A2R8YGL0> , <https://identifiers.org/uniprot/Q92574> , <https://identifiers.org/uniprot/A0A2R8YD74> , <https://identifiers.org/uniprot/A0A2R8Y6N1> , <https://identifiers.org/uniprot/A0A2R8Y5M3> , <https://identifiers.org/uniprot/A0A2R8Y5J1> , <https://identifiers.org/uniprot/A0A2R8Y5S3> , <https://identifiers.org/uniprot/Q59IT9> , <https://identifiers.org/uniprot/A0A2R8Y5Q4> , <https://identifiers.org/uniprot/A0A2R8YGX7> , <https://identifiers.org/uniprot/A0A2R8Y6S1> , <https://identifiers.org/uniprot/X5D9D2> , <https://identifiers.org/uniprot/Q86WV8> , <https://identifiers.org/uniprot/A0A2R8YFV7> , <https://identifiers.org/uniprot/A0A2R8YEH9> , <https://identifiers.org/uniprot/A0A2R8Y7E9> , <https://identifiers.org/uniprot/A0A2R8Y5N2> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q14908113> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/c2ebb> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A2R8YD74> , <http://purl.uniprot.org/uniprot/Q86WV8> , <http://purl.uniprot.org/uniprot/Q92574> , <http://purl.uniprot.org/uniprot/A0A2R8Y7E9> , <http://purl.uniprot.org/uniprot/A0A2R8YGL0> , <http://purl.uniprot.org/uniprot/X5D9D2> , <http://purl.uniprot.org/uniprot/A0A2R8YFV7> , <http://purl.uniprot.org/uniprot/A0A2R8Y6S8> , <http://purl.uniprot.org/uniprot/A0A2R8Y6W1> , <http://purl.uniprot.org/uniprot/A0A2R8YGX7> , <http://purl.uniprot.org/uniprot/A0A2R8Y5M3> , <http://purl.uniprot.org/uniprot/A0A2R8Y419> , <http://purl.uniprot.org/uniprot/A0A2R8Y756> , <http://purl.uniprot.org/uniprot/A0A2R8Y6S1> , <http://purl.uniprot.org/uniprot/A0A2R8Y6N1> , <http://purl.uniprot.org/uniprot/Q59IT9> , <http://purl.uniprot.org/uniprot/A0A2R8Y6T5> , <http://purl.uniprot.org/uniprot/A0A2R8Y5U8> , <http://purl.uniprot.org/uniprot/A0A2R8Y5S3> , <http://purl.uniprot.org/uniprot/A0A2R8Y5N2> , <http://purl.uniprot.org/uniprot/A0A2R8Y5J1> , <http://purl.uniprot.org/uniprot/A0A2R8Y5Q4> , <http://purl.uniprot.org/uniprot/A0A2R8Y5F8> , <http://purl.uniprot.org/uniprot/A0A2R8YEH9> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000165699> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/e157f>
        rdf:type            wp:Interaction , wp:Stimulation , wp:DirectedInteraction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/15971998> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/e157f> ;
        wp:participants     <https://identifiers.org/ensembl/ENSG00000117020> , <https://identifiers.org/ensembl/ENSG00000136111> ;
        wp:source           <https://identifiers.org/ensembl/ENSG00000117020> ;
        wp:target           <https://identifiers.org/ensembl/ENSG00000136111> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/eaf92>
        rdf:type            wp:Binding , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/17666482> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/eaf92> ;
        wp:participants     <https://identifiers.org/ensembl/ENSG00000123104> , <https://identifiers.org/chebi/CHEBI:16595> ;
        wp:source           <https://identifiers.org/chebi/CHEBI:16595> ;
        wp:target           <https://identifiers.org/ensembl/ENSG00000123104> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/ed87e>
        rdf:type            wp:Stimulation , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/15964803> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/ed87e> ;
        wp:participants     <https://identifiers.org/chebi/CHEBI:17489> , <https://identifiers.org/uniprot/A0A0A0MSC1> ;
        wp:source           <https://identifiers.org/uniprot/A0A0A0MSC1> ;
        wp:target           <https://identifiers.org/chebi/CHEBI:17489> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/cb62d>
        rdf:type            wp:DirectedInteraction , wp:Interaction , wp:Stimulation ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/18329679> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/cb62d> ;
        wp:participants     <https://identifiers.org/ensembl/ENSG00000174775> , <https://identifiers.org/ensembl/ENSG00000132155> ;
        wp:source           <https://identifiers.org/ensembl/ENSG00000174775> ;
        wp:target           <https://identifiers.org/ensembl/ENSG00000132155> .

obo:NCBITaxon_9606  obo:NCIT_C179773  "9606" .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/af27e>
        rdf:type            wp:DirectedInteraction , wp:Interaction , wp:Stimulation ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/15964803> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/af27e> ;
        wp:participants     <https://identifiers.org/ensembl/ENSG00000107175> , <https://identifiers.org/uniprot/Q15136> ;
        wp:source           <https://identifiers.org/uniprot/Q15136> ;
        wp:target           <https://identifiers.org/ensembl/ENSG00000107175> .

<https://identifiers.org/uniprot/A0A024R2W7>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "MKK3" ;
        dc:identifier       <https://identifiers.org/uniprot/A0A024R2W7> ;
        dc:source           "UniProtKB" ;
        dcterms:identifier  "A0A024R2W7" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/f5893> , <https://identifiers.org/wikipathways/WP4746_r140519> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/d4ed4> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000114738> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/7867> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/MAPKAPK3> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A024R2W7> , <https://identifiers.org/uniprot/C9J8E1> , <https://identifiers.org/uniprot/C9JPW3> , <https://identifiers.org/uniprot/H7C0G6> , <https://identifiers.org/uniprot/Q16644> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/fbfe1> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/C9JPW3> , <http://purl.uniprot.org/uniprot/Q16644> , <http://purl.uniprot.org/uniprot/H7C0G6> , <http://purl.uniprot.org/uniprot/C9J8E1> , <http://purl.uniprot.org/uniprot/A0A024R2W7> ;
        foaf:page           <http://www.uniprot.org/uniprot/A0A024R2W7> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/bb990>
        rdf:type            wp:Interaction , wp:Stimulation , wp:DirectedInteraction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/17666482> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/bb990> ;
        wp:participants     <https://identifiers.org/chebi/CHEBI:29108> , <https://identifiers.org/ensembl/ENSG00000123104> ;
        wp:source           <https://identifiers.org/ensembl/ENSG00000123104> ;
        wp:target           <https://identifiers.org/chebi/CHEBI:29108> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/c4d63>
        rdf:type            wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/29997323> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/c4d63> ;
        wp:participants     <https://identifiers.org/chebi/CHEBI:18258> ;
        wp:source           <https://identifiers.org/chebi/CHEBI:18258> ;
        wp:target           <https://identifiers.org/chebi/CHEBI:18258> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/ComplexBinding/dce5b>
        rdf:type          wp:ComplexBinding , wp:Binding , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4746_r140519> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Group/dce5b> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000186350> , <https://identifiers.org/chebi/CHEBI:18258> , <https://identifiers.org/ensembl/ENSG00000151090> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Complex/dce5b> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/ddc3d>
        rdf:type            wp:Inhibition , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/17720805> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/ddc3d> ;
        wp:participants     <https://identifiers.org/ensembl/ENSG00000164690> , <https://identifiers.org/ensembl/ENSG00000211448> ;
        wp:source           <https://identifiers.org/ensembl/ENSG00000164690> ;
        wp:target           <https://identifiers.org/ensembl/ENSG00000211448> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/bb9a8>
        rdf:type            wp:Interaction , wp:Stimulation , wp:DirectedInteraction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/17720805> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/bb9a8> ;
        wp:participants     <https://identifiers.org/ensembl/ENSG00000164690> , <https://identifiers.org/ensembl/ENSG00000197406> ;
        wp:source           <https://identifiers.org/ensembl/ENSG00000164690> ;
        wp:target           <https://identifiers.org/ensembl/ENSG00000197406> .

<https://identifiers.org/pubmed/28322461>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "28322461" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/f8243> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/28322461> .

<https://identifiers.org/ensembl/ENSG00000162552>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "Wnt" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000162552> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000162552" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/a79b0> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/a742d> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000162552> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/54361> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/WNT4> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/P56705> , <https://identifiers.org/uniprot/B1AJZ6> , <https://identifiers.org/uniprot/H0Y663> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q15321841> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/fc11b> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P56705> , <http://purl.uniprot.org/uniprot/H0Y663> , <http://purl.uniprot.org/uniprot/B1AJZ6> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000162552> .

<https://identifiers.org/uniprot/Q16539>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "p38" ;
        dc:identifier       <https://identifiers.org/uniprot/Q16539> ;
        dc:source           "UniProtKB" ;
        dcterms:identifier  "Q16539" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/e64f6> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/ebd7b> , <https://identifiers.org/wikipathways/WP4746_r140519> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/f5893> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/dc028> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000112062> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/1432> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/MAPK14> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/E7EX54> , <https://identifiers.org/uniprot/B4E0K5> , <https://identifiers.org/uniprot/B5TY33> , <https://identifiers.org/uniprot/H7C4E2> , <https://identifiers.org/uniprot/L7RSM2> , <https://identifiers.org/uniprot/A0A024RD15> , <https://identifiers.org/uniprot/Q16539> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/e061d> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/B4E0K5> , <http://purl.uniprot.org/uniprot/Q16539> , <http://purl.uniprot.org/uniprot/E7EX54> , <http://purl.uniprot.org/uniprot/A0A024RD15> , <http://purl.uniprot.org/uniprot/H7C4E2> , <http://purl.uniprot.org/uniprot/B5TY33> , <http://purl.uniprot.org/uniprot/L7RSM2> ;
        foaf:page           <http://www.uniprot.org/uniprot/Q16539> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/b820f>
        rdf:type          wp:Stimulation , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4746_r140519> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/b820f> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000121879> , <https://identifiers.org/ensembl/ENSG00000151090> ;
        wp:source         <https://identifiers.org/ensembl/ENSG00000151090> ;
        wp:target         <https://identifiers.org/ensembl/ENSG00000121879> .

<https://identifiers.org/chebi/CHEBI:29101>
        rdf:type            wp:Metabolite , wp:DataNode ;
        rdfs:label          "Na⁺" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/FKNQFGJONOIPTF-UHFFFAOYSA-N> ;
        dc:identifier       <https://identifiers.org/chebi/CHEBI:29101> ;
        dc:source           "ChEBI" ;
        dcterms:identifier  "CHEBI:29101" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/f12e2> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/a83c5> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:29101> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/899> ;
        wp:bdbHmdb          <https://identifiers.org/hmdb/HMDB0000588> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/FKNQFGJONOIPTF-UHFFFAOYSA-N> ;
        wp:bdbKeggCompound  <https://identifiers.org/kegg.compound/C01330> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID923> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q3154110> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/ba458> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/a4404> ;
        foaf:page           <https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:29101> .

<https://identifiers.org/pubmed/22353746>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "22353746" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/bb638> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/22353746> .

<https://identifiers.org/chebi/CHEBI:17489>
        rdf:type            wp:Metabolite , wp:DataNode ;
        rdfs:label          "cAMP" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/IVOMOUWHDPKRLL-KQYNXXCUSA-N> ;
        dc:identifier       <https://identifiers.org/chebi/CHEBI:17489> ;
        dc:source           "ChEBI" ;
        dcterms:identifier  "CHEBI:17489" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/ee727> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/d437f> , <https://identifiers.org/wikipathways/WP4746_r140519> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/ac99f> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/ded54> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/ed87e> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:17489> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/5851> ;
        wp:bdbHmdb          <https://identifiers.org/hmdb/HMDB0000058> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/IVOMOUWHDPKRLL-KQYNXXCUSA-N> ;
        wp:bdbKeggCompound  <https://identifiers.org/kegg.compound/C00575> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID6076> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q210041> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/cda95> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/d21a8> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/d3252> ;
        foaf:page           <https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:17489> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/ComplexBinding/b6566>
        rdf:type          wp:ComplexBinding , wp:Binding , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4746_r140519> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Group/b6566> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000259207> , <https://identifiers.org/ensembl/ENSG00000138448> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Complex/b6566> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/b1649>
        rdf:type            wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/19196800> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/b1649> ;
        wp:participants     <https://identifiers.org/chebi/CHEBI:16382> , <https://identifiers.org/ensembl/ENSG00000105641> ;
        wp:source           <https://identifiers.org/ensembl/ENSG00000105641> ;
        wp:target           <https://identifiers.org/chebi/CHEBI:16382> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/a9728>
        rdf:type            wp:DirectedInteraction , wp:Interaction , wp:Stimulation ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/18329679> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/a9728> ;
        wp:participants     <https://identifiers.org/ensembl/ENSG00000121879> , <https://identifiers.org/ensembl/ENSG00000197122> ;
        wp:source           <https://identifiers.org/ensembl/ENSG00000197122> ;
        wp:target           <https://identifiers.org/ensembl/ENSG00000121879> .

<https://identifiers.org/ensembl/ENSG00000126351>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "THRA1" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000126351> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000126351" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Complex/de5d5> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000126351> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/7067> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/THRA> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/P10827> , <https://identifiers.org/uniprot/J3QRW5> , <https://identifiers.org/uniprot/J3QR26> , <https://identifiers.org/uniprot/J3QRA9> , <https://identifiers.org/uniprot/J3KTF3> , <https://identifiers.org/uniprot/Q6FH41> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18031986> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/ed9cd> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/J3QRW5> , <http://purl.uniprot.org/uniprot/J3KTF3> , <http://purl.uniprot.org/uniprot/J3QRA9> , <http://purl.uniprot.org/uniprot/J3QR26> , <http://purl.uniprot.org/uniprot/P10827> , <http://purl.uniprot.org/uniprot/Q6FH41> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000126351> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/be8be>
        rdf:type            wp:DirectedInteraction , wp:Interaction , wp:Catalysis ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/17574010> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/be8be> ;
        wp:participants     <https://identifiers.org/ensembl/ENSG00000197406> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/c39e7> ;
        wp:source           <https://identifiers.org/ensembl/ENSG00000197406> ;
        wp:target           <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/c39e7> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/abcb7>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4746_r140519> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/abcb7> ;
        wp:participants   <https://identifiers.org/chebi/CHEBI:33569> ;
        wp:source         <https://identifiers.org/chebi/CHEBI:33569> ;
        wp:target         <https://identifiers.org/chebi/CHEBI:33569> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/ComplexBinding/de5d5>
        rdf:type          wp:ComplexBinding , wp:Binding , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4746_r140519> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Group/de5d5> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000126351> , <https://identifiers.org/chebi/CHEBI:18258> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Complex/de5d5> .

<https://identifiers.org/ensembl/ENSG00000115904>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "SOS" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000115904> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000115904" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/e9749> , <https://identifiers.org/wikipathways/WP4746_r140519> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000115904> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/6654> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/SOS1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q07889> , <https://identifiers.org/uniprot/A0A8I5KP47> , <https://identifiers.org/uniprot/G5E9C8> , <https://identifiers.org/uniprot/A0A8I5QJD1> , <https://identifiers.org/uniprot/A0A8I5KV97> , <https://identifiers.org/uniprot/A0A8I5QJ77> , <https://identifiers.org/uniprot/A0A8I5KY52> , <https://identifiers.org/uniprot/A0A8I5KWL0> , <https://identifiers.org/uniprot/C9K0N6> , <https://identifiers.org/uniprot/A0A8I5QJF3> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q14908123> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/d9eb6> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A8I5QJF3> , <http://purl.uniprot.org/uniprot/C9K0N6> , <http://purl.uniprot.org/uniprot/A0A8I5QJ77> , <http://purl.uniprot.org/uniprot/Q07889> , <http://purl.uniprot.org/uniprot/A0A8I5KWL0> , <http://purl.uniprot.org/uniprot/G5E9C8> , <http://purl.uniprot.org/uniprot/A0A8I5KV97> , <http://purl.uniprot.org/uniprot/A0A8I5KP47> , <http://purl.uniprot.org/uniprot/A0A8I5KY52> , <http://purl.uniprot.org/uniprot/A0A8I5QJD1> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000115904> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/bf6ae>
        rdf:type            wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/29997323> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/bf6ae> ;
        wp:participants     <https://identifiers.org/chebi/CHEBI:18332> , <https://identifiers.org/uniprot/P36021> ;
        wp:source           <https://identifiers.org/uniprot/P36021> ;
        wp:target           <https://identifiers.org/chebi/CHEBI:18332> .

<https://identifiers.org/ensembl/ENSG00000077782>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "FGFR1" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000077782> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000077782" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Complex/c5bc4> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000077782> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/2260> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/FGFR1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/E9PN14> , <https://identifiers.org/uniprot/P11362> , <https://identifiers.org/uniprot/C9J205> , <https://identifiers.org/uniprot/A0A6I8PRY1> , <https://identifiers.org/uniprot/H0YE20> , <https://identifiers.org/uniprot/E9PKX3> , <https://identifiers.org/uniprot/A0A994J419> , <https://identifiers.org/uniprot/A0A8I3B1S4> , <https://identifiers.org/uniprot/A0A0S2Z3Q6> , <https://identifiers.org/uniprot/E9PKF2> , <https://identifiers.org/uniprot/C9J1L5> , <https://identifiers.org/uniprot/A0A0S2Z3T4> , <https://identifiers.org/uniprot/A0A6I8PTV4> , <https://identifiers.org/uniprot/E9PQ40> , <https://identifiers.org/uniprot/B5A958> , <https://identifiers.org/uniprot/E9PNM3> , <https://identifiers.org/uniprot/A0A804HIF1> , <https://identifiers.org/uniprot/A0A3B3ISD1> , <https://identifiers.org/uniprot/E9PKV7> , <https://identifiers.org/uniprot/E7EU09> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q14914258> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/b0f67> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/C9J205> , <http://purl.uniprot.org/uniprot/E9PNM3> , <http://purl.uniprot.org/uniprot/A0A0S2Z3Q6> , <http://purl.uniprot.org/uniprot/A0A8I3B1S4> , <http://purl.uniprot.org/uniprot/B5A958> , <http://purl.uniprot.org/uniprot/A0A804HIF1> , <http://purl.uniprot.org/uniprot/A0A0S2Z3T4> , <http://purl.uniprot.org/uniprot/A0A6I8PTV4> , <http://purl.uniprot.org/uniprot/E9PKF2> , <http://purl.uniprot.org/uniprot/A0A994J419> , <http://purl.uniprot.org/uniprot/A0A6I8PRY1> , <http://purl.uniprot.org/uniprot/E9PN14> , <http://purl.uniprot.org/uniprot/P11362> , <http://purl.uniprot.org/uniprot/E9PKV7> , <http://purl.uniprot.org/uniprot/H0YE20> , <http://purl.uniprot.org/uniprot/A0A3B3ISD1> , <http://purl.uniprot.org/uniprot/E9PQ40> , <http://purl.uniprot.org/uniprot/E9PKX3> , <http://purl.uniprot.org/uniprot/C9J1L5> , <http://purl.uniprot.org/uniprot/E7EU09> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000077782> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/cac71>
        rdf:type            wp:Inhibition , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/29997323> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/cac71> ;
        wp:participants     <https://identifiers.org/kegg.pathway/map04150> , <https://identifiers.org/ensembl/ENSG00000115138> ;
        wp:source           <https://identifiers.org/kegg.pathway/map04150> ;
        wp:target           <https://identifiers.org/ensembl/ENSG00000115138> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/e3c81>
        rdf:type            wp:Interaction , wp:DirectedInteraction , wp:Binding ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/24820868> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/e3c81> ;
        wp:participants     <https://identifiers.org/uniprot/A0A087X094> , <https://identifiers.org/uniprot/P16066> ;
        wp:source           <https://identifiers.org/uniprot/A0A087X094> ;
        wp:target           <https://identifiers.org/uniprot/P16066> .

<https://identifiers.org/ensembl/ENSG00000107175>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "CREB" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000107175> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000107175" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/b8bdc> , <https://identifiers.org/wikipathways/WP4746_r140519> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Complex/ca727> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/af27e> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000107175> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/10488> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/CREB3> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/O43889> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18035427> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/a2f91> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/a88ea> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/O43889> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000107175> .

<https://identifiers.org/chebi/CHEBI:25400>
        rdf:type            wp:DataNode , wp:Metabolite ;
        rdfs:label          "MIT" ;
        dc:identifier       <https://identifiers.org/chebi/CHEBI:25400> ;
        dc:source           "ChEBI" ;
        dcterms:identifier  "CHEBI:25400" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/dfc95> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:25400> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/e9d20> ;
        foaf:page           <https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:25400> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/bc893>
        rdf:type            wp:DirectedInteraction , wp:Interaction , wp:Inhibition ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/18467435> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/bc893> ;
        wp:participants     <https://identifiers.org/ensembl/ENSG00000082701> , <https://identifiers.org/ensembl/ENSG00000117020> ;
        wp:source           <https://identifiers.org/ensembl/ENSG00000117020> ;
        wp:target           <https://identifiers.org/ensembl/ENSG00000082701> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/f0352>
        rdf:type          wp:Stimulation , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4746_r140519> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/f0352> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000109819> , <https://identifiers.org/ensembl/ENSG00000115966> ;
        wp:source         <https://identifiers.org/ensembl/ENSG00000115966> ;
        wp:target         <https://identifiers.org/ensembl/ENSG00000109819> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/dfc95>
        rdf:type            wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/20167242> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/dfc95> ;
        wp:participants     <https://identifiers.org/chebi/CHEBI:16382> , <https://identifiers.org/chebi/CHEBI:25400> ;
        wp:source           <https://identifiers.org/chebi/CHEBI:25400> ;
        wp:target           <https://identifiers.org/chebi/CHEBI:16382> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/d2708>
        rdf:type          wp:Stimulation , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4746_r140519> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/d2708> ;
        wp:participants   <https://identifiers.org/chebi/CHEBI:16595> , <https://identifiers.org/uniprot/A0A087WT80> ;
        wp:source         <https://identifiers.org/uniprot/A0A087WT80> ;
        wp:target         <https://identifiers.org/chebi/CHEBI:16595> .

<https://identifiers.org/uniprot/A0A0A0MSC1>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "Adenylate cyclase" ;
        dc:identifier       <https://identifiers.org/uniprot/A0A0A0MSC1> ;
        dc:source           "UniProtKB" ;
        dcterms:identifier  "A0A0A0MSC1" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/c188b> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/ed87e> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000138031> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/109> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/ADCY3> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/O60266> , <https://identifiers.org/uniprot/U3KQR1> , <https://identifiers.org/uniprot/U3KQ91> , <https://identifiers.org/uniprot/C9JYB5> , <https://identifiers.org/uniprot/C9JLX3> , <https://identifiers.org/uniprot/C9J969> , <https://identifiers.org/uniprot/H7C1A6> , <https://identifiers.org/uniprot/A0A0A0MSC1> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/d195d> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/H7C1A6> , <http://purl.uniprot.org/uniprot/A0A0A0MSC1> , <http://purl.uniprot.org/uniprot/C9JLX3> , <http://purl.uniprot.org/uniprot/C9J969> , <http://purl.uniprot.org/uniprot/U3KQ91> , <http://purl.uniprot.org/uniprot/C9JYB5> , <http://purl.uniprot.org/uniprot/U3KQR1> , <http://purl.uniprot.org/uniprot/O60266> ;
        foaf:page           <http://www.uniprot.org/uniprot/A0A0A0MSC1> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/eea5e>
        rdf:type            wp:Interaction , wp:Stimulation , wp:DirectedInteraction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/29997323> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/eea5e> ;
        wp:participants     <https://identifiers.org/ensembl/ENSG00000166603> , <https://identifiers.org/ensembl/ENSG00000115138> ;
        wp:source           <https://identifiers.org/ensembl/ENSG00000115138> ;
        wp:target           <https://identifiers.org/ensembl/ENSG00000166603> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/d0f36>
        rdf:type            wp:DirectedInteraction , wp:Inhibition , wp:Interaction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/12172553> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/d0f36> ;
        wp:participants     <https://identifiers.org/ensembl/ENSG00000103197> , <https://identifiers.org/ensembl/ENSG00000106615> ;
        wp:source           <https://identifiers.org/ensembl/ENSG00000103197> ;
        wp:target           <https://identifiers.org/ensembl/ENSG00000106615> .

<https://identifiers.org/pubmed/24872083>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "24872083" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/bfea0> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/d235f> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/beb87> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/c5d51> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/24872083> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/e39b8>
        rdf:type            wp:Binding , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/20167242> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/e39b8> ;
        wp:participants     <https://identifiers.org/uniprot/E5RG33> ;
        wp:source           <https://identifiers.org/uniprot/E5RG33> ;
        wp:target           <https://identifiers.org/uniprot/E5RG33> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/Complex/ca727>
        rdf:type          wp:Complex , wp:DataNode ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4746_r140519> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Group/ca727> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000107175> , <https://identifiers.org/uniprot/A0A140TA56> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/e64a3>
        rdf:type            wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/17574010> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/e64a3> ;
        wp:participants     <https://identifiers.org/chebi/CHEBI:18258> , <https://identifiers.org/uniprot/P36021> ;
        wp:source           <https://identifiers.org/uniprot/P36021> ;
        wp:target           <https://identifiers.org/chebi/CHEBI:18258> .

<https://identifiers.org/pubmed/25330987>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "25330987" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/a5f46> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/25330987> .

<https://identifiers.org/ensembl/ENSG00000082701>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "GSK3B" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000082701> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000082701" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/c8f3a> , <https://identifiers.org/wikipathways/WP4746_r140519> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/bc893> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000082701> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/2932> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/GSK3B> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A7I2YQK2> , <https://identifiers.org/uniprot/A0A7I2V4X2> , <https://identifiers.org/uniprot/A0A7I2V5P4> , <https://identifiers.org/uniprot/A0A7I2V3S5> , <https://identifiers.org/uniprot/A0A7I2V4F3> , <https://identifiers.org/uniprot/A0A7I2V441> , <https://identifiers.org/uniprot/A0A7I2V675> , <https://identifiers.org/uniprot/A0A7I2V3J4> , <https://identifiers.org/uniprot/A0A7I2V432> , <https://identifiers.org/uniprot/A0A7I2V589> , <https://identifiers.org/uniprot/A0A3B3ITW1> , <https://identifiers.org/uniprot/A0A7I2YQ81> , <https://identifiers.org/uniprot/Q6FI27> , <https://identifiers.org/uniprot/A0A7I2V2N4> , <https://identifiers.org/uniprot/A0A7I2YQK0> , <https://identifiers.org/uniprot/A0A7I2V4X3> , <https://identifiers.org/uniprot/A0A7I2V2I5> , <https://identifiers.org/uniprot/A0A7I2V5B5> , <https://identifiers.org/uniprot/A0A7I2V606> , <https://identifiers.org/uniprot/A0A7I2V3K8> , <https://identifiers.org/uniprot/A0A7I2V2V4> , <https://identifiers.org/uniprot/A0A7I2V5K9> , <https://identifiers.org/uniprot/A0A7I2V5M2> , <https://identifiers.org/uniprot/A0A7I2V3A4> , <https://identifiers.org/uniprot/A0A7I2V2Y0> , <https://identifiers.org/uniprot/A0A7I2YQB0> , <https://identifiers.org/uniprot/A0A7I2V2U4> , <https://identifiers.org/uniprot/A0A7I2V4G2> , <https://identifiers.org/uniprot/A0A7I2V3D8> , <https://identifiers.org/uniprot/A0A7I2V626> , <https://identifiers.org/uniprot/P49841> , <https://identifiers.org/uniprot/A0A7I2YQG6> , <https://identifiers.org/uniprot/A0A7I2V2K7> , <https://identifiers.org/uniprot/A0A7I2V5G5> , <https://identifiers.org/uniprot/A0A7I2V3T3> , <https://identifiers.org/uniprot/A0A7I2V3G9> , <https://identifiers.org/uniprot/A0A7I2YQU1> , <https://identifiers.org/uniprot/A0A7I2V4W7> , <https://identifiers.org/uniprot/A0A7I2V3N7> , <https://identifiers.org/uniprot/A0A7I2V2T2> , <https://identifiers.org/uniprot/A0A7I2V3Z5> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18258585> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/cbb6f> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A7I2V3D8> , <http://purl.uniprot.org/uniprot/P49841> , <http://purl.uniprot.org/uniprot/A0A7I2V675> , <http://purl.uniprot.org/uniprot/A0A7I2YQK2> , <http://purl.uniprot.org/uniprot/A0A7I2V2U4> , <http://purl.uniprot.org/uniprot/A0A7I2V3G9> , <http://purl.uniprot.org/uniprot/A0A7I2V2T2> , <http://purl.uniprot.org/uniprot/A0A7I2V3N7> , <http://purl.uniprot.org/uniprot/A0A3B3ITW1> , <http://purl.uniprot.org/uniprot/A0A7I2V4X3> , <http://purl.uniprot.org/uniprot/A0A7I2YQG6> , <http://purl.uniprot.org/uniprot/A0A7I2V2N4> , <http://purl.uniprot.org/uniprot/A0A7I2V2V4> , <http://purl.uniprot.org/uniprot/A0A7I2V441> , <http://purl.uniprot.org/uniprot/A0A7I2V4F3> , <http://purl.uniprot.org/uniprot/A0A7I2V3Z5> , <http://purl.uniprot.org/uniprot/Q6FI27> , <http://purl.uniprot.org/uniprot/A0A7I2V3T3> , <http://purl.uniprot.org/uniprot/A0A7I2V3J4> , <http://purl.uniprot.org/uniprot/A0A7I2V4G2> , <http://purl.uniprot.org/uniprot/A0A7I2V4X2> , <http://purl.uniprot.org/uniprot/A0A7I2V2Y0> , <http://purl.uniprot.org/uniprot/A0A7I2V3A4> , <http://purl.uniprot.org/uniprot/A0A7I2V3S5> , <http://purl.uniprot.org/uniprot/A0A7I2V432> , <http://purl.uniprot.org/uniprot/A0A7I2V4W7> , <http://purl.uniprot.org/uniprot/A0A7I2V5M2> , <http://purl.uniprot.org/uniprot/A0A7I2YQB0> , <http://purl.uniprot.org/uniprot/A0A7I2V626> , <http://purl.uniprot.org/uniprot/A0A7I2V589> , <http://purl.uniprot.org/uniprot/A0A7I2V2K7> , <http://purl.uniprot.org/uniprot/A0A7I2V3K8> , <http://purl.uniprot.org/uniprot/A0A7I2YQU1> , <http://purl.uniprot.org/uniprot/A0A7I2V5G5> , <http://purl.uniprot.org/uniprot/A0A7I2V2I5> , <http://purl.uniprot.org/uniprot/A0A7I2V606> , <http://purl.uniprot.org/uniprot/A0A7I2V5K9> , <http://purl.uniprot.org/uniprot/A0A7I2YQ81> , <http://purl.uniprot.org/uniprot/A0A7I2V5B5> , <http://purl.uniprot.org/uniprot/A0A7I2YQK0> , <http://purl.uniprot.org/uniprot/A0A7I2V5P4> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000082701> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/a08be>
        rdf:type            wp:DirectedInteraction , wp:Interaction , wp:Catalysis ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/20167242> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/a08be> ;
        wp:participants     <https://identifiers.org/uniprot/E9PFM6> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/e3b59> ;
        wp:source           <https://identifiers.org/uniprot/E9PFM6> ;
        wp:target           <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/e3b59> .

<https://identifiers.org/ensembl/ENSG00000259207>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "ITGB" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000259207> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000259207" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Complex/b6566> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Complex/a0028> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000259207> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/3690> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/ITGB3> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/P05106> , <https://identifiers.org/uniprot/Q16157> , <https://identifiers.org/uniprot/I3L4X8> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q14913635> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/ec128> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/afe86> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/I3L4X8> , <http://purl.uniprot.org/uniprot/P05106> , <http://purl.uniprot.org/uniprot/Q16157> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000259207> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/Complex/ae4e2>
        rdf:type          wp:Complex , wp:DataNode ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4746_r140519> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Group/ae4e2> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000142611> , <https://identifiers.org/ensembl/ENSG00000004487> , <https://identifiers.org/ensembl/ENSG00000101493> .

<https://identifiers.org/pubmed/21683758>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "21683758" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/a8e9e> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/bd79b> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/21683758> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/cf0e5>
        rdf:type            wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/29997323> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/cf0e5> ;
        wp:participants     <https://identifiers.org/chebi/CHEBI:18332> ;
        wp:source           <https://identifiers.org/chebi/CHEBI:18332> ;
        wp:target           <https://identifiers.org/chebi/CHEBI:18332> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/ac99f>
        rdf:type            wp:Binding , wp:Interaction , wp:DirectedInteraction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/20378719> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/ac99f> ;
        wp:participants     <https://identifiers.org/chebi/CHEBI:17489> , <https://identifiers.org/uniprot/Q15136> ;
        wp:source           <https://identifiers.org/chebi/CHEBI:17489> ;
        wp:target           <https://identifiers.org/uniprot/Q15136> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/aad88>
        rdf:type            wp:Interaction , wp:DirectedInteraction , wp:Stimulation ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/28235572> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/aad88> ;
        wp:participants     <https://identifiers.org/ensembl/ENSG00000123836> , <https://identifiers.org/ensembl/ENSG00000117020> ;
        wp:source           <https://identifiers.org/ensembl/ENSG00000117020> ;
        wp:target           <https://identifiers.org/ensembl/ENSG00000123836> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/d0a5e>
        rdf:type          wp:Stimulation , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4746_r140519> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/d0a5e> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000109424> , <https://identifiers.org/ensembl/ENSG00000115966> ;
        wp:source         <https://identifiers.org/ensembl/ENSG00000115966> ;
        wp:target         <https://identifiers.org/ensembl/ENSG00000109424> .

<https://identifiers.org/ensembl/ENSG00000117020>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "AKT" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000117020> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000117020" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/e8b0f> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/d6efc> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/aad88> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/daf19> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/e157f> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/bc893> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/bc0ce> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/b0701> , <https://identifiers.org/wikipathways/WP4746_r140519> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/b15ce> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000117020> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/10000> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/AKT3> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q9Y243> , <https://identifiers.org/uniprot/A0A7P0TB29> , <https://identifiers.org/uniprot/A0A7P0TBJ6> , <https://identifiers.org/uniprot/A0A5F9ZHA9> , <https://identifiers.org/uniprot/A0A5K1VW74> , <https://identifiers.org/uniprot/A0A7P0T8T9> , <https://identifiers.org/uniprot/A0A7P0T872> , <https://identifiers.org/uniprot/A0A7P0TB32> , <https://identifiers.org/uniprot/A0A5F9ZHU3> , <https://identifiers.org/uniprot/A0A5F9ZGY0> , <https://identifiers.org/uniprot/A0A5F9ZGZ4> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18034943> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/e0a73> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q9Y243> , <http://purl.uniprot.org/uniprot/A0A5F9ZGZ4> , <http://purl.uniprot.org/uniprot/A0A7P0T8T9> , <http://purl.uniprot.org/uniprot/A0A7P0TBJ6> , <http://purl.uniprot.org/uniprot/A0A5F9ZHU3> , <http://purl.uniprot.org/uniprot/A0A5K1VW74> , <http://purl.uniprot.org/uniprot/A0A7P0TB32> , <http://purl.uniprot.org/uniprot/A0A5F9ZHA9> , <http://purl.uniprot.org/uniprot/A0A7P0T872> , <http://purl.uniprot.org/uniprot/A0A5F9ZGY0> , <http://purl.uniprot.org/uniprot/A0A7P0TB29> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000117020> .

<https://identifiers.org/chebi/CHEBI:16356>
        rdf:type            wp:DataNode , wp:Metabolite ;
        rdfs:label          "cGMP" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/ZOOGRGPOEVQQDX-UUOKFMHZSA-N> ;
        dc:identifier       <https://identifiers.org/chebi/CHEBI:16356> ;
        dc:source           "ChEBI" ;
        dcterms:identifier  "CHEBI:16356" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/ebd53> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/ef13e> , <https://identifiers.org/wikipathways/WP4746_r140519> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:16356> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/22734> ;
        wp:bdbHmdb          <https://identifiers.org/hmdb/HMDB0001314> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/ZOOGRGPOEVQQDX-UUOKFMHZSA-N> ;
        wp:bdbKeggCompound  <https://identifiers.org/kegg.compound/C00942> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID24316> , <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID135398570> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q422511> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/f108a> ;
        foaf:page           <https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:16356> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/b8bcd>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4746_r140519> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/b8bcd> ;
        wp:participants   <https://identifiers.org/chebi/CHEBI:18258> , <https://identifiers.org/uniprot/P36021> ;
        wp:source         <https://identifiers.org/uniprot/P36021> ;
        wp:target         <https://identifiers.org/chebi/CHEBI:18258> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/b4f20>
        rdf:type            wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/12172553> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/b4f20> ;
        wp:participants     <https://identifiers.org/wikipathways/WP3318> , <https://identifiers.org/ensembl/ENSG00000198793> ;
        wp:source           <https://identifiers.org/ensembl/ENSG00000198793> ;
        wp:target           <https://identifiers.org/wikipathways/WP3318> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/ComplexBinding/a0028>
        rdf:type          wp:ComplexBinding , wp:Binding , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4746_r140519> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Group/a0028> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000259207> , <https://identifiers.org/ensembl/ENSG00000138448> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Complex/a0028> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/ebd7b>
        rdf:type            wp:Interaction , wp:Stimulation , wp:DirectedInteraction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/24820868> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/ebd7b> ;
        wp:participants     <https://identifiers.org/uniprot/A0A140VJM3> , <https://identifiers.org/uniprot/Q16539> ;
        wp:source           <https://identifiers.org/uniprot/A0A140VJM3> ;
        wp:target           <https://identifiers.org/uniprot/Q16539> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/daf19>
        rdf:type            wp:Interaction , wp:DirectedInteraction , wp:Inhibition ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/31076567> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/daf19> ;
        wp:participants     <https://identifiers.org/ensembl/ENSG00000117020> , <https://identifiers.org/ensembl/ENSG00000132906> ;
        wp:source           <https://identifiers.org/ensembl/ENSG00000117020> ;
        wp:target           <https://identifiers.org/ensembl/ENSG00000132906> .

<https://identifiers.org/ensembl/ENSG00000112394>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "SLC16A10" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000112394> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000112394" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/be36b> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/dc852> , <https://identifiers.org/wikipathways/WP4746_r140519> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000112394> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/117247> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/SLC16A10> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q8TF71> , <https://identifiers.org/uniprot/H0Y5M8> , <https://identifiers.org/uniprot/H0Y3W8> , <https://identifiers.org/uniprot/Q9P1I2> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18049291> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/c7693> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/dd7ed> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/H0Y5M8> , <http://purl.uniprot.org/uniprot/H0Y3W8> , <http://purl.uniprot.org/uniprot/Q9P1I2> , <http://purl.uniprot.org/uniprot/Q8TF71> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000112394> .

<https://identifiers.org/uniprot/E9PFM6>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "TPO" ;
        dc:identifier       <https://identifiers.org/uniprot/E9PFM6> ;
        dc:source           "UniProtKB" ;
        dcterms:identifier  "E9PFM6" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/a08be> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000115705> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/7173> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/TPO> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/H7C1F5> , <https://identifiers.org/uniprot/H0Y6H4> , <https://identifiers.org/uniprot/H7C5B6> , <https://identifiers.org/uniprot/E9PFM6> , <https://identifiers.org/uniprot/C9J511> , <https://identifiers.org/uniprot/P07202> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/dd68f> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/E9PFM6> , <http://purl.uniprot.org/uniprot/C9J511> , <http://purl.uniprot.org/uniprot/H7C1F5> , <http://purl.uniprot.org/uniprot/H7C5B6> , <http://purl.uniprot.org/uniprot/H0Y6H4> , <http://purl.uniprot.org/uniprot/P07202> ;
        foaf:page           <http://www.uniprot.org/uniprot/E9PFM6> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/Complex/b06b4>
        rdf:type          wp:Complex , wp:DataNode ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4746_r140519> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Group/b06b4> ;
        wp:participants   <https://identifiers.org/chebi/CHEBI:18258> , <https://identifiers.org/uniprot/P10827> , <https://identifiers.org/ensembl/ENSG00000186350> .

<https://identifiers.org/pubmed/21440011>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "21440011" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/ae922> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/dc595> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/b15ce> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/c65ca> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/21440011> .

<https://identifiers.org/ensembl/ENSG00000106615>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "RHEB" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000106615> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000106615" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/d0f36> , <https://identifiers.org/wikipathways/WP4746_r140519> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/dda4f> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000106615> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/6009> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/RHEB> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q15382> , <https://identifiers.org/uniprot/C9J469> , <https://identifiers.org/uniprot/C9J931> , <https://identifiers.org/uniprot/A0A090N900> , <https://identifiers.org/uniprot/F8WBL3> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18031127> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/b532f> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/fbd49> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q15382> , <http://purl.uniprot.org/uniprot/A0A090N900> , <http://purl.uniprot.org/uniprot/C9J469> , <http://purl.uniprot.org/uniprot/F8WBL3> , <http://purl.uniprot.org/uniprot/C9J931> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000106615> .

<https://identifiers.org/ensembl/ENSG00000072133>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "RPS6KA6" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000072133> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000072133" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/d56a8> , <https://identifiers.org/wikipathways/WP4746_r140519> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000072133> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/27330> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/RPS6KA6> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q9UK32> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/af80c> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q9UK32> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000072133> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/b5914>
        rdf:type            wp:Stimulation , wp:Interaction , wp:DirectedInteraction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/18329679> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/b5914> ;
        wp:participants     <https://identifiers.org/uniprot/A0A087X0I9> , <https://identifiers.org/chebi/CHEBI:29108> ;
        wp:source           <https://identifiers.org/chebi/CHEBI:29108> ;
        wp:target           <https://identifiers.org/uniprot/A0A087X0I9> .

<https://identifiers.org/ensembl/ENSG00000135540>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "NHSL" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000135540> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000135540" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/d235f> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/bfea0> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/d3591> , <https://identifiers.org/wikipathways/WP4746_r140519> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000135540> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/57224> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/NHSL1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/E9PMJ0> , <https://identifiers.org/uniprot/H0YDF6> , <https://identifiers.org/uniprot/Q5SYE7> , <https://identifiers.org/uniprot/E9PAK2> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18042990> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/f79e4> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/H0YDF6> , <http://purl.uniprot.org/uniprot/E9PAK2> , <http://purl.uniprot.org/uniprot/E9PMJ0> , <http://purl.uniprot.org/uniprot/Q5SYE7> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000135540> .

<https://identifiers.org/ensembl/ENSG00000166225>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "FRS2" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000166225> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000166225" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/deb7f> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000166225> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/10818> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/FRS2> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/F8VS98> , <https://identifiers.org/uniprot/L7RTG7> , <https://identifiers.org/uniprot/F8VX65> , <https://identifiers.org/uniprot/F8VP54> , <https://identifiers.org/uniprot/F8VZ12> , <https://identifiers.org/uniprot/F8VZI4> , <https://identifiers.org/uniprot/Q8WU20> , <https://identifiers.org/uniprot/F8VW66> , <https://identifiers.org/uniprot/A0A0G2JL00> , <https://identifiers.org/uniprot/F8VYZ7> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18035859> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/b6412> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A0G2JL00> , <http://purl.uniprot.org/uniprot/L7RTG7> , <http://purl.uniprot.org/uniprot/F8VP54> , <http://purl.uniprot.org/uniprot/F8VW66> , <http://purl.uniprot.org/uniprot/F8VZI4> , <http://purl.uniprot.org/uniprot/Q8WU20> , <http://purl.uniprot.org/uniprot/F8VYZ7> , <http://purl.uniprot.org/uniprot/F8VS98> , <http://purl.uniprot.org/uniprot/F8VZ12> , <http://purl.uniprot.org/uniprot/F8VX65> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000166225> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/d5821>
        rdf:type            wp:Stimulation , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/15964803> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/d5821> ;
        wp:participants     <https://identifiers.org/uniprot/G3V4Q4> , <https://identifiers.org/uniprot/Q15136> ;
        wp:source           <https://identifiers.org/uniprot/Q15136> ;
        wp:target           <https://identifiers.org/uniprot/G3V4Q4> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/b68fc>
        rdf:type            wp:DirectedInteraction , wp:Stimulation , wp:Interaction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/27681418> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/b68fc> ;
        wp:participants     <https://identifiers.org/ensembl/ENSG00000137154> , <https://identifiers.org/ensembl/ENSG00000109424> ;
        wp:source           <https://identifiers.org/ensembl/ENSG00000137154> ;
        wp:target           <https://identifiers.org/ensembl/ENSG00000109424> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/ComplexBinding/e9b9c>
        rdf:type          wp:ComplexBinding , wp:Binding , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4746_r140519> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Group/e9b9c> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000132170> , <https://identifiers.org/ensembl/ENSG00000077080> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Complex/e9b9c> .

<https://identifiers.org/chebi/CHEBI:29264>
        rdf:type            wp:DataNode , wp:Metabolite ;
        rdfs:label          "tRNAsec" ;
        dc:identifier       <https://identifiers.org/chebi/CHEBI:29264> ;
        dc:source           "ChEBI" ;
        dcterms:identifier  "CHEBI:29264" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Complex/b8acc> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:29264> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/a08fb> ;
        foaf:page           <https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:29264> .

<https://identifiers.org/ensembl/ENSG00000197122>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "SRC" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000197122> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000197122" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/a9728> , <https://identifiers.org/wikipathways/WP4746_r140519> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000197122> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/6714> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/SRC> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A8I5KYU4> , <https://identifiers.org/uniprot/P12931> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q424737> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/bd878> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A8I5KYU4> , <http://purl.uniprot.org/uniprot/P12931> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000197122> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/d86d8>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4746_r140519> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/d86d8> ;
        wp:participants   <https://identifiers.org/chebi/CHEBI:18258> , <https://identifiers.org/uniprot/P36021> ;
        wp:source         <https://identifiers.org/uniprot/P36021> ;
        wp:target         <https://identifiers.org/chebi/CHEBI:18258> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/f12e2>
        rdf:type          wp:Binding , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4746_r140519> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/f12e2> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000105641> , <https://identifiers.org/chebi/CHEBI:29101> ;
        wp:source         <https://identifiers.org/chebi/CHEBI:29101> ;
        wp:target         <https://identifiers.org/ensembl/ENSG00000105641> .

<https://identifiers.org/wikipathways/WP661>
        rdf:type            wp:DataNode , wp:Pathway ;
        rdfs:label          "Glucose metabolism" ;
        dc:identifier       <https://identifiers.org/wikipathways/WP661> ;
        dc:source           "WikiPathways" ;
        dcterms:identifier  "WP661" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/e1b11> , <https://identifiers.org/wikipathways/WP4746_r140519> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/f4707> ;
        foaf:page           <https://www.wikipathways.org/instance/WP661> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/dc595>
        rdf:type            wp:Interaction , wp:DirectedInteraction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/21440011> , <https://identifiers.org/pubmed/9346240> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/dc595> ;
        wp:participants     <https://identifiers.org/kegg.pathway/hsa04211> , <https://identifiers.org/ensembl/ENSG00000002330> ;
        wp:source           <https://identifiers.org/ensembl/ENSG00000002330> ;
        wp:target           <https://identifiers.org/kegg.pathway/hsa04211> .

<https://identifiers.org/ensembl/ENSG00000115138>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "POMC" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000115138> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000115138" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/cac71> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/eea5e> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000115138> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/5443> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/POMC> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/E9PHK5> , <https://identifiers.org/uniprot/P01189> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q14819793> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/e8363> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P01189> , <http://purl.uniprot.org/uniprot/E9PHK5> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000115138> .

<https://identifiers.org/kegg.pathway/hsa04931>
        rdf:type            wp:Pathway , wp:DataNode ;
        rdfs:label          "Glucose transport" ;
        dc:identifier       <https://identifiers.org/kegg.pathway/hsa04931> ;
        dc:source           "KEGG Pathway" ;
        dcterms:identifier  "hsa04931" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/d4a02> , <https://identifiers.org/wikipathways/WP4746_r140519> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/e0286> ;
        foaf:page           <http://www.genome.jp/dbget-bin/www_bget?pathway+hsa04931> .

<https://identifiers.org/ensembl/ENSG00000077463>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "SIRT6" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000077463> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000077463" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/afd0b> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000077463> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/51548> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/SIRT6> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/M0QZ09> , <https://identifiers.org/uniprot/Q8N6T7> , <https://identifiers.org/uniprot/M0R0B2> , <https://identifiers.org/uniprot/M0R1N9> , <https://identifiers.org/uniprot/M0R1F6> , <https://identifiers.org/uniprot/M0QXA0> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18040385> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/ce78c> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/M0QXA0> , <http://purl.uniprot.org/uniprot/M0R1F6> , <http://purl.uniprot.org/uniprot/M0R1N9> , <http://purl.uniprot.org/uniprot/M0QZ09> , <http://purl.uniprot.org/uniprot/Q8N6T7> , <http://purl.uniprot.org/uniprot/M0R0B2> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000077463> .

<https://identifiers.org/pubmed/21317437>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "21317437" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/e0070> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/dc028> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/e64f6> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/21317437> .

<https://identifiers.org/kegg.pathway/map04330>
        rdf:type            wp:Pathway , wp:DataNode ;
        rdfs:label          "NOTCH signaling" ;
        dc:identifier       <https://identifiers.org/kegg.pathway/map04330> ;
        dc:source           "KEGG Pathway" ;
        dcterms:identifier  "map04330" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/a5f46> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/f346c> ;
        foaf:page           <http://www.genome.jp/dbget-bin/www_bget?pathway+map04330> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/a036f>
        rdf:type            wp:Binding , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/20167242> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/a036f> ;
        wp:participants     <https://identifiers.org/uniprot/E5RG33> ;
        wp:source           <https://identifiers.org/uniprot/E5RG33> ;
        wp:target           <https://identifiers.org/uniprot/E5RG33> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/c188b>
        rdf:type            wp:Interaction , wp:DirectedInteraction , wp:Stimulation ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/28448947> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/c188b> ;
        wp:participants     <https://identifiers.org/uniprot/A0A0A0MSC1> , <https://identifiers.org/uniprot/P13945> ;
        wp:source           <https://identifiers.org/uniprot/P13945> ;
        wp:target           <https://identifiers.org/uniprot/A0A0A0MSC1> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/dc028>
        rdf:type            wp:Stimulation , wp:Interaction , wp:DirectedInteraction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/21317437> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/dc028> ;
        wp:participants     <https://identifiers.org/ensembl/ENSG00000109819> , <https://identifiers.org/uniprot/Q16539> ;
        wp:source           <https://identifiers.org/uniprot/Q16539> ;
        wp:target           <https://identifiers.org/ensembl/ENSG00000109819> .

<https://identifiers.org/pubmed/11149600>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "11149600" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/c586d> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/11149600> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/ebd53>
        rdf:type            wp:DirectedInteraction , wp:Interaction , wp:Binding ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/24820868> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/ebd53> ;
        wp:participants     <https://identifiers.org/uniprot/A0A140VJM3> , <https://identifiers.org/chebi/CHEBI:16356> ;
        wp:source           <https://identifiers.org/chebi/CHEBI:16356> ;
        wp:target           <https://identifiers.org/uniprot/A0A140VJM3> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/e1b11>
        rdf:type            wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/28235572> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/e1b11> ;
        wp:participants     <https://identifiers.org/wikipathways/WP661> , <https://identifiers.org/ensembl/ENSG00000123836> ;
        wp:source           <https://identifiers.org/ensembl/ENSG00000123836> ;
        wp:target           <https://identifiers.org/wikipathways/WP661> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/b8a42>
        rdf:type            wp:Interaction , wp:DirectedInteraction , wp:Inhibition ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/18329679> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/b8a42> ;
        wp:participants     <https://identifiers.org/ensembl/ENSG00000135679> , <https://identifiers.org/ensembl/ENSG00000141510> ;
        wp:source           <https://identifiers.org/ensembl/ENSG00000135679> ;
        wp:target           <https://identifiers.org/ensembl/ENSG00000141510> .

<https://identifiers.org/pubmed/11533250>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "11533250" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/a742d> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/a79b0> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/11533250> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/af51b>
        rdf:type            wp:Interaction , wp:Binding , wp:DirectedInteraction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/20167242> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/af51b> ;
        wp:participants     <https://identifiers.org/uniprot/E5RG33> , <https://identifiers.org/chebi/CHEBI:16382> ;
        wp:source           <https://identifiers.org/chebi/CHEBI:16382> ;
        wp:target           <https://identifiers.org/uniprot/E5RG33> .

<https://identifiers.org/chebi/CHEBI:23796>
        rdf:type            wp:DataNode , wp:Metabolite ;
        rdfs:label          "DIT" ;
        dc:identifier       <https://identifiers.org/chebi/CHEBI:23796> ;
        dc:source           "ChEBI" ;
        dcterms:identifier  "CHEBI:23796" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/a5b51> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/f3bf4> , <https://identifiers.org/wikipathways/WP4746_r140519> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:23796> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/ef7ae> ;
        foaf:page           <https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:23796> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/e4718>
        rdf:type            wp:Interaction , wp:DirectedInteraction , wp:Stimulation ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/22653837> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/e4718> ;
        wp:participants     <https://identifiers.org/uniprot/Q02750> , <https://identifiers.org/uniprot/Q15136> ;
        wp:source           <https://identifiers.org/uniprot/Q15136> ;
        wp:target           <https://identifiers.org/uniprot/Q02750> .

<https://identifiers.org/ensembl/ENSG00000148400>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "NOTCH" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000148400> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000148400" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/a5f46> , <https://identifiers.org/wikipathways/WP4746_r140519> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000148400> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/4851> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/NOTCH1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A7P0T9V1> , <https://identifiers.org/uniprot/A0A7P0Z4H9> , <https://identifiers.org/uniprot/A0A7P0TBG2> , <https://identifiers.org/uniprot/A0A7P0TB20> , <https://identifiers.org/uniprot/A0A7P0T8U6> , <https://identifiers.org/uniprot/A0A7P0TA56> , <https://identifiers.org/uniprot/P46531> , <https://identifiers.org/uniprot/A0A7P0TAK8> , <https://identifiers.org/uniprot/A0A7P0T8W1> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18252685> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/c3895> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P46531> , <http://purl.uniprot.org/uniprot/A0A7P0TB20> , <http://purl.uniprot.org/uniprot/A0A7P0TAK8> , <http://purl.uniprot.org/uniprot/A0A7P0TBG2> , <http://purl.uniprot.org/uniprot/A0A7P0T9V1> , <http://purl.uniprot.org/uniprot/A0A7P0TA56> , <http://purl.uniprot.org/uniprot/A0A7P0T8U6> , <http://purl.uniprot.org/uniprot/A0A7P0T8W1> , <http://purl.uniprot.org/uniprot/A0A7P0Z4H9> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000148400> .

<https://identifiers.org/ensembl/ENSG00000002330>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "BAD" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000002330> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000002330" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/bc0ce> , <https://identifiers.org/wikipathways/WP4746_r140519> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/dc595> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000002330> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/572> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/BAD> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q92934> , <https://identifiers.org/uniprot/F5H3B1> , <https://identifiers.org/uniprot/A8MXU7> , <https://identifiers.org/uniprot/F5H1R6> , <https://identifiers.org/uniprot/F5GYS3> , <https://identifiers.org/uniprot/A0A024R562> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q14907705> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/c13f0> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q92934> , <http://purl.uniprot.org/uniprot/F5H1R6> , <http://purl.uniprot.org/uniprot/F5GYS3> , <http://purl.uniprot.org/uniprot/A8MXU7> , <http://purl.uniprot.org/uniprot/F5H3B1> , <http://purl.uniprot.org/uniprot/A0A024R562> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000002330> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/f2651>
        rdf:type            wp:Interaction , wp:Stimulation , wp:DirectedInteraction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/20378719> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/f2651> ;
        wp:participants     <https://identifiers.org/uniprot/A0A0K0K1K3> , <https://identifiers.org/ensembl/ENSG00000165409> ;
        wp:source           <https://identifiers.org/ensembl/ENSG00000165409> ;
        wp:target           <https://identifiers.org/uniprot/A0A0K0K1K3> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/d68fa>
        rdf:type            wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/17574010> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/d68fa> ;
        wp:participants     <https://identifiers.org/chebi/CHEBI:18258> ;
        wp:source           <https://identifiers.org/chebi/CHEBI:18258> ;
        wp:target           <https://identifiers.org/chebi/CHEBI:18258> .

<https://identifiers.org/ensembl/ENSG00000177885>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "GRB2" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000177885> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000177885" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/e9749> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/eac33> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/deb7f> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000177885> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/2885> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/GRB2> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/P62993> , <https://identifiers.org/uniprot/J3KT38> , <https://identifiers.org/uniprot/B0LPF3> , <https://identifiers.org/uniprot/J3QLF6> , <https://identifiers.org/uniprot/J3QRL5> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q14905188> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/ea3c8> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/J3QRL5> , <http://purl.uniprot.org/uniprot/B0LPF3> , <http://purl.uniprot.org/uniprot/P62993> , <http://purl.uniprot.org/uniprot/J3QLF6> , <http://purl.uniprot.org/uniprot/J3KT38> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000177885> .

<https://identifiers.org/ensembl/ENSG00000108443>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "RPS6KB1" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000108443> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000108443" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/a3ac8> , <https://identifiers.org/wikipathways/WP4746_r140519> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000108443> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/6198> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/RPS6KB1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/K7EIM2> , <https://identifiers.org/uniprot/P23443> , <https://identifiers.org/uniprot/K7ER06> , <https://identifiers.org/uniprot/K7EMM2> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18031289> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/b1b70> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/K7ER06> , <http://purl.uniprot.org/uniprot/K7EIM2> , <http://purl.uniprot.org/uniprot/K7EMM2> , <http://purl.uniprot.org/uniprot/P23443> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000108443> .

<https://identifiers.org/pubmed/17666482>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "17666482" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/fad79> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/eaf92> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/bb990> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/17666482> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/ComplexBinding/ca727>
        rdf:type          wp:ComplexBinding , wp:Binding , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4746_r140519> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Group/ca727> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000107175> , <https://identifiers.org/uniprot/A0A140TA56> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Complex/ca727> .

<https://identifiers.org/ensembl/ENSG00000198793>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "mTOR" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000198793> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000198793" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/dda4f> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Complex/c7580> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/b4f20> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000198793> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/2475> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/MTOR> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A8V8TRG9> , <https://identifiers.org/uniprot/A0A8V8TR74> , <https://identifiers.org/uniprot/A0A8V8TQN3> , <https://identifiers.org/uniprot/A0A8V8TQM6> , <https://identifiers.org/uniprot/A0A8V8TQ52> , <https://identifiers.org/uniprot/P42345> , <https://identifiers.org/uniprot/A0A8V8TQP2> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q14876086> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/dcdb5> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/de8c2> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P42345> , <http://purl.uniprot.org/uniprot/A0A8V8TQP2> , <http://purl.uniprot.org/uniprot/A0A8V8TQ52> , <http://purl.uniprot.org/uniprot/A0A8V8TQM6> , <http://purl.uniprot.org/uniprot/A0A8V8TRG9> , <http://purl.uniprot.org/uniprot/A0A8V8TR74> , <http://purl.uniprot.org/uniprot/A0A8V8TQN3> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000198793> .

<https://identifiers.org/chebi/CHEBI:18009>
        rdf:type            wp:DataNode , wp:Metabolite ;
        rdfs:label          "NADP+" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/XJLXINKUBYWONI-NNYOXOHSSA-N> ;
        dc:identifier       <https://identifiers.org/chebi/CHEBI:18009> ;
        dc:source           "ChEBI" ;
        dcterms:identifier  "CHEBI:18009" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/b96dd> , <https://identifiers.org/wikipathways/WP4746_r140519> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:18009> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/5675> ;
        wp:bdbHmdb          <https://identifiers.org/hmdb/HMDB0304435> , <https://identifiers.org/hmdb/HMDB0000217> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/XJLXINKUBYWONI-NNYOXOHSSA-O> ;
        wp:bdbKeggCompound  <https://identifiers.org/kegg.compound/C00006> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID5886> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q26987754> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/f3485> ;
        foaf:page           <https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:18009> .

<https://identifiers.org/pubmed/27351946>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "27351946" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/db5ae> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/cae86> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/27351946> .

<https://identifiers.org/uniprot/A0A087WT80>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "PLC" ;
        dc:identifier       <https://identifiers.org/uniprot/A0A087WT80> ;
        dc:source           "UniProtKB" ;
        dcterms:identifier  "A0A087WT80" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/a37c2> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/d2708> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/fb9fe> , <https://identifiers.org/wikipathways/WP4746_r140519> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/c658c> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/fad79> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A087WT80> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/caadd> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/f0fdb> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A087WT80> ;
        foaf:page           <http://www.uniprot.org/uniprot/A0A087WT80> .

<https://identifiers.org/wikipathways/WP4746_r140519>
        rdf:type                wp:Pathway , skos:Collection ;
        dc:identifier           <https://identifiers.org/wikipathways/WP4746> ;
        dc:source               "WikiPathways" ;
        dc:title                "Thyroid hormones production and peripheral downstream signaling effects"@en ;
        dcterms:description     "Congenital hypothyroidism is a genetic hormonal disorder of the thyroid hormone. Due to dyshormonogenesis, the production of the thyroid hormones is impaired resulting in increased birth weight, reduced LDL breakdown, decreased lipolysis, impaired glucose metabolism and decreased body temperature. This pathway diagram shows an overview of thyroid hormones production in thyroid gland and their relevant downstream signaling. Genes affected by mutations leading to congenital hypothyroidism are colored red." ;
        dcterms:identifier      "WP4746" ;
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        wp:organism             obo:NCBITaxon_9606 ;
        wp:organismName         "Homo sapiens" ;
        wp:pathwayOntologyTag   obo:PW_0000013 , obo:PW_0001200 ;
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<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/bcb57>
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<https://identifiers.org/pubmed/28723567>
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<https://identifiers.org/ensembl/ENSG00000197406>
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<https://identifiers.org/pubmed/24463099>
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        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/24463099> .

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        wp:source           <https://identifiers.org/ensembl/ENSG00000132155> ;
        wp:target           <https://identifiers.org/uniprot/Q02750> .

<https://identifiers.org/ensembl/ENSG00000004487>
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        foaf:page           <https://www.ensembl.org/id/ENSG00000004487> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/deb7f>
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        wp:participants     <https://identifiers.org/ensembl/ENSG00000177885> , <https://identifiers.org/ensembl/ENSG00000166225> ;
        wp:source           <https://identifiers.org/ensembl/ENSG00000166225> ;
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<https://identifiers.org/uniprot/P16066>
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<http://rdf.wikipathways.org/Pathway/WP4746_r140519/ComplexBinding/f4317>
        rdf:type          wp:ComplexBinding , wp:Binding , wp:Interaction ;
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        wp:participants   <https://identifiers.org/ensembl/ENSG00000151090> , <https://identifiers.org/chebi/CHEBI:18258> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Complex/f4317> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/b96dd>
        rdf:type          wp:Conversion , wp:DirectedInteraction , wp:Interaction ;
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        wp:participants   <https://identifiers.org/chebi/CHEBI:18009> , <https://identifiers.org/chebi/CHEBI:16474> ;
        wp:source         <https://identifiers.org/chebi/CHEBI:16474> ;
        wp:target         <https://identifiers.org/chebi/CHEBI:18009> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/ComplexBinding/b8acc>
        rdf:type          wp:ComplexBinding , wp:Binding , wp:Interaction ;
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        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Group/b8acc> ;
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<https://identifiers.org/ensembl/ENSG00000142611>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "PRDM16" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000142611> ;
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        dcterms:identifier  "ENSG00000142611" ;
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        foaf:page           <https://www.ensembl.org/id/ENSG00000142611> .

<https://identifiers.org/uniprot/A0A087X0I9>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "PKC" ;
        dc:identifier       <https://identifiers.org/uniprot/A0A087X0I9> ;
        dc:source           "UniProtKB" ;
        dcterms:identifier  "A0A087X0I9" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/b8bdc> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/b5914> , <https://identifiers.org/wikipathways/WP4746_r140519> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/f4a25> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/b7188> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/f8243> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/e2761> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/bd79b> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A087X0I9> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/ba430> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/bd896> ;
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        foaf:page           <http://www.uniprot.org/uniprot/A0A087X0I9> .

<https://identifiers.org/ensembl/ENSG00000134962>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "KLB" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000134962> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000134962" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Complex/c5bc4> , <https://identifiers.org/wikipathways/WP4746_r140519> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000134962> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/152831> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/KLB> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q86Z14> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18052211> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/e78ce> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q86Z14> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000134962> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/a37c2>
        rdf:type            wp:Stimulation , wp:Interaction , wp:DirectedInteraction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/20378719> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/a37c2> ;
        wp:participants     <https://identifiers.org/chebi/CHEBI:18035> , <https://identifiers.org/uniprot/A0A087WT80> ;
        wp:source           <https://identifiers.org/uniprot/A0A087WT80> ;
        wp:target           <https://identifiers.org/chebi/CHEBI:18035> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/b9e72>
        rdf:type            wp:Interaction , wp:DirectedInteraction , wp:Binding ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/17574010> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/b9e72> ;
        wp:participants     <https://identifiers.org/chebi/CHEBI:18258> , <https://identifiers.org/uniprot/P36021> ;
        wp:source           <https://identifiers.org/chebi/CHEBI:18258> ;
        wp:target           <https://identifiers.org/uniprot/P36021> .

<https://identifiers.org/chebi/CHEBI:29108>
        rdf:type            wp:DataNode , wp:Metabolite ;
        rdfs:label          "Ca²⁺" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/BHPQYMZQTOCNFJ-UHFFFAOYSA-N> ;
        dc:identifier       <https://identifiers.org/chebi/CHEBI:29108> ;
        dc:source           "ChEBI" ;
        dcterms:identifier  "CHEBI:29108" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/c194f> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/a8e9e> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/bb990> , <https://identifiers.org/wikipathways/WP4746_r140519> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/b5914> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:29108> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/266> ;
        wp:bdbHmdb          <https://identifiers.org/hmdb/HMDB0000464> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/BHPQYMZQTOCNFJ-UHFFFAOYSA-N> ;
        wp:bdbKeggCompound  <https://identifiers.org/kegg.compound/C00076> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID271> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q23905776> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/e29d3> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/eaf33> ;
        foaf:page           <https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:29108> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/ComplexBinding/d5116>
        rdf:type          wp:ComplexBinding , wp:Binding , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4746_r140519> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Group/d5116> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000165699> , <https://identifiers.org/ensembl/ENSG00000103197> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Complex/d5116> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/f4a25>
        rdf:type            wp:DirectedInteraction , wp:Binding , wp:Interaction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/20378719> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/f4a25> ;
        wp:participants     <https://identifiers.org/chebi/CHEBI:18035> , <https://identifiers.org/uniprot/A0A087X0I9> ;
        wp:source           <https://identifiers.org/chebi/CHEBI:18035> ;
        wp:target           <https://identifiers.org/uniprot/A0A087X0I9> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/e02af>
        rdf:type            wp:Interaction , wp:DirectedInteraction , wp:Binding ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/24820868> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/e02af> ;
        wp:participants     <https://identifiers.org/uniprot/P16860> , <https://identifiers.org/uniprot/P16066> ;
        wp:source           <https://identifiers.org/uniprot/P16860> ;
        wp:target           <https://identifiers.org/uniprot/P16066> .

<https://identifiers.org/wikipathways/WP1403>
        rdf:type            wp:Pathway , wp:DataNode ;
        rdfs:label          "MAPK signalling" ;
        dc:identifier       <https://identifiers.org/wikipathways/WP1403> ;
        dc:source           "WikiPathways" ;
        dcterms:identifier  "WP1403" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/ecd71> ;
        foaf:page           <https://www.wikipathways.org/instance/WP1403> .

<https://identifiers.org/ensembl/ENSG00000135679>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "MDM2" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000135679> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000135679" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/b0701> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/b8a42> , <https://identifiers.org/wikipathways/WP4746_r140519> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000135679> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/4193> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/MDM2> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/E7EMW5> , <https://identifiers.org/uniprot/F5H4Q8> , <https://identifiers.org/uniprot/Q9H4C5> , <https://identifiers.org/uniprot/F5GWH7> , <https://identifiers.org/uniprot/G3XA89> , <https://identifiers.org/uniprot/A7UKX8> , <https://identifiers.org/uniprot/J3KN53> , <https://identifiers.org/uniprot/E7EPE2> , <https://identifiers.org/uniprot/A0A0C4DFR5> , <https://identifiers.org/uniprot/E5RJQ0> , <https://identifiers.org/uniprot/F6UXB6> , <https://identifiers.org/uniprot/Q96DS5> , <https://identifiers.org/uniprot/A0A0A8KB88> , <https://identifiers.org/uniprot/A0A0A8K986> , <https://identifiers.org/uniprot/J3QST1> , <https://identifiers.org/uniprot/Q9H4C3> , <https://identifiers.org/uniprot/A0A0A8KBA1> , <https://identifiers.org/uniprot/F5GZB0> , <https://identifiers.org/uniprot/Q00987> , <https://identifiers.org/uniprot/E5RHE2> , <https://identifiers.org/uniprot/F5GZC3> , <https://identifiers.org/uniprot/A0A1B0GXJ6> , <https://identifiers.org/uniprot/F5H1M7> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18028978> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/b824e> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/F5H1M7> , <http://purl.uniprot.org/uniprot/Q9H4C5> , <http://purl.uniprot.org/uniprot/E7EMW5> , <http://purl.uniprot.org/uniprot/A0A0A8KBA1> , <http://purl.uniprot.org/uniprot/A0A0C4DFR5> , <http://purl.uniprot.org/uniprot/F5GWH7> , <http://purl.uniprot.org/uniprot/J3QST1> , <http://purl.uniprot.org/uniprot/F5GZB0> , <http://purl.uniprot.org/uniprot/E5RJQ0> , <http://purl.uniprot.org/uniprot/E5RHE2> , <http://purl.uniprot.org/uniprot/A0A0A8KB88> , <http://purl.uniprot.org/uniprot/F5GZC3> , <http://purl.uniprot.org/uniprot/Q9H4C3> , <http://purl.uniprot.org/uniprot/A0A0A8K986> , <http://purl.uniprot.org/uniprot/G3XA89> , <http://purl.uniprot.org/uniprot/F6UXB6> , <http://purl.uniprot.org/uniprot/J3KN53> , <http://purl.uniprot.org/uniprot/Q96DS5> , <http://purl.uniprot.org/uniprot/Q00987> , <http://purl.uniprot.org/uniprot/A0A1B0GXJ6> , <http://purl.uniprot.org/uniprot/F5H4Q8> , <http://purl.uniprot.org/uniprot/A7UKX8> , <http://purl.uniprot.org/uniprot/E7EPE2> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000135679> .

<https://identifiers.org/uniprot/E5RG33>
        rdf:type            wp:Protein , wp:Complex , wp:DataNode ;
        rdfs:label          "TG bound MIT, DIT, T3 and T4" , "TG bound MIT and DIT" , "TG" ;
        dc:identifier       <https://identifiers.org/uniprot/E5RG33> ;
        dc:source           "UniProtKB" ;
        dcterms:identifier  "E5RG33" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/e3b59> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/fc91b> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/af51b> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/dd399> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/a5b51> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/c29dc> , <https://identifiers.org/wikipathways/WP4746_r140519> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/e39b8> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/a036f> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000042832> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/7038> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/TG> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/H0YB42> , <https://identifiers.org/uniprot/P01266> , <https://identifiers.org/uniprot/H0YBL4> , <https://identifiers.org/uniprot/E7EVM0> , <https://identifiers.org/uniprot/H0YBJ2> , <https://identifiers.org/uniprot/E5RG33> , <https://identifiers.org/uniprot/H0YBY1> , <https://identifiers.org/uniprot/H0YBQ6> , <https://identifiers.org/uniprot/H0YBR7> , <https://identifiers.org/uniprot/H0YBC5> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/fef60> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/bd07d> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/a4dab> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/a2fe9> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/H0YBY1> , <http://purl.uniprot.org/uniprot/E5RG33> , <http://purl.uniprot.org/uniprot/H0YBC5> , <http://purl.uniprot.org/uniprot/H0YBQ6> , <http://purl.uniprot.org/uniprot/P01266> , <http://purl.uniprot.org/uniprot/H0YBR7> , <http://purl.uniprot.org/uniprot/H0YBL4> , <http://purl.uniprot.org/uniprot/E7EVM0> , <http://purl.uniprot.org/uniprot/H0YBJ2> , <http://purl.uniprot.org/uniprot/H0YB42> ;
        foaf:page           <http://www.uniprot.org/uniprot/E5RG33> .

<https://identifiers.org/ensembl/ENSG00000211448>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "DIO2" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000211448> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000211448" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/bb638> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/ddc3d> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/cae86> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000211448> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/1734> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/DIO2> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/H0YJ42> , <https://identifiers.org/uniprot/Q92813> , <https://identifiers.org/uniprot/G3V3A8> , <https://identifiers.org/uniprot/H0YJQ8> , <https://identifiers.org/uniprot/G3V2A7> , <https://identifiers.org/uniprot/A0A024R6J8> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q17914005> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/c8f85> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/fd450> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/e50cf> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/G3V2A7> , <http://purl.uniprot.org/uniprot/H0YJQ8> , <http://purl.uniprot.org/uniprot/G3V3A8> , <http://purl.uniprot.org/uniprot/A0A024R6J8> , <http://purl.uniprot.org/uniprot/H0YJ42> , <http://purl.uniprot.org/uniprot/Q92813> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000211448> .

<https://doi.org/10.1016%2Fj.softx.2024.101701>
        rdf:type            wp:PublicationReference ;
        dc:source           "DOI" ;
        dcterms:identifier  "10.1016/j.softx.2024.101701" ;
        cito:cites          <https://identifiers.org/wikipathways/WP4746> .

<https://identifiers.org/chebi/CHEBI:89575>
        rdf:type            wp:Metabolite , wp:DataNode ;
        rdfs:label          "T2" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/ZHSOTLOTTDYIIK-UHFFFAOYSA-N> ;
        dc:identifier       <https://identifiers.org/chebi/CHEBI:89575> ;
        dc:source           "ChEBI" ;
        dcterms:identifier  "CHEBI:89575" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/c39e7> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:89575> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/110252> ;
        wp:bdbHmdb          <https://identifiers.org/hmdb/HMDB0000582> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/ZHSOTLOTTDYIIK-UHFFFAOYSA-N> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID123675> , <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID44366756> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q20888848> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/d0eec> ;
        foaf:page           <https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:89575> .

<https://identifiers.org/pubmed/25390014>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "25390014" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/cde4d> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/a4d61> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/b6ec1> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/fd422> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/b9e67> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/25390014> .

<https://identifiers.org/pubmed/28448947>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "28448947" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/c188b> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/de2da> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/28448947> .

<https://identifiers.org/kegg.pathway/map04150>
        rdf:type            wp:Pathway , wp:DataNode ;
        rdfs:label          "mTOR" ;
        dc:identifier       <https://identifiers.org/kegg.pathway/map04150> ;
        dc:source           "KEGG Pathway" ;
        dcterms:identifier  "map04150" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/cac71> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/e90a1> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/c4245> ;
        foaf:page           <http://www.genome.jp/dbget-bin/www_bget?pathway+map04150> .

<https://identifiers.org/chebi/CHEBI:16382>
        rdf:type            wp:DataNode , wp:Metabolite ;
        rdfs:label          "iodide" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/XMBWDFGMSWQBCA-UHFFFAOYSA-N> ;
        dc:identifier       <https://identifiers.org/chebi/CHEBI:16382> ;
        dc:source           "ChEBI" ;
        dcterms:identifier  "CHEBI:16382" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/af51b> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/c95ba> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/e56cc> , <https://identifiers.org/wikipathways/WP4746_r140519> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/dfc95> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/b1649> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/f3bf4> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/e0065> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/ca42b> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:16382> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/28015> ;
        wp:bdbHmdb          <https://identifiers.org/hmdb/HMDB0012238> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/XMBWDFGMSWQBCA-UHFFFAOYSA-M> ;
        wp:bdbKeggCompound  <https://identifiers.org/kegg.compound/C00708> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID30165> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q407654> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/a7392> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/e88d9> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/f1f4f> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/dd0aa> ;
        foaf:page           <https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:16382> .

<https://identifiers.org/ensembl/ENSG00000121879>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "PI3K" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000121879> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000121879" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/b820f> , <https://identifiers.org/wikipathways/WP4746_r140519> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/df053> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/a9728> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000121879> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/5290> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/PIK3CA> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/P42336> , <https://identifiers.org/uniprot/A0A2R8Y2F6> , <https://identifiers.org/uniprot/A0A6Q8PGV1> , <https://identifiers.org/uniprot/C9JAM9> , <https://identifiers.org/uniprot/C9J951> , <https://identifiers.org/uniprot/A0A6Q8PGN9> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q14887700> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/f4dd0> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/C9J951> , <http://purl.uniprot.org/uniprot/C9JAM9> , <http://purl.uniprot.org/uniprot/P42336> , <http://purl.uniprot.org/uniprot/A0A2R8Y2F6> , <http://purl.uniprot.org/uniprot/A0A6Q8PGV1> , <http://purl.uniprot.org/uniprot/A0A6Q8PGN9> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000121879> .

<https://identifiers.org/uniprot/Q15136>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "PKA" ;
        dc:identifier       <https://identifiers.org/uniprot/Q15136> ;
        dc:source           "UniProtKB" ;
        dcterms:identifier  "Q15136" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/e4718> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/d5821> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/beb87> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/d437f> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/a744d> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/da923> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/af27e> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/ded54> , <https://identifiers.org/wikipathways/WP4746_r140519> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/c586d> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/ac99f> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/bfea0> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000072062> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/5566> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/PRKACA> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A7I2V5J4> , <https://identifiers.org/uniprot/P17612> , <https://identifiers.org/uniprot/Q15136> , <https://identifiers.org/uniprot/K7ENJ5> , <https://identifiers.org/uniprot/A0A8V8TL59> , <https://identifiers.org/uniprot/A0A024R7J0> , <https://identifiers.org/uniprot/K7EMV1> , <https://identifiers.org/uniprot/B7Z708> , <https://identifiers.org/uniprot/A0A7I2YQ82> , <https://identifiers.org/uniprot/K7ERP6> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/cac9e> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/cedbb> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/eb98d> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A024R7J0> , <http://purl.uniprot.org/uniprot/A0A8V8TL59> , <http://purl.uniprot.org/uniprot/K7EMV1> , <http://purl.uniprot.org/uniprot/B7Z708> , <http://purl.uniprot.org/uniprot/Q15136> , <http://purl.uniprot.org/uniprot/P17612> , <http://purl.uniprot.org/uniprot/K7ERP6> , <http://purl.uniprot.org/uniprot/A0A7I2YQ82> , <http://purl.uniprot.org/uniprot/K7ENJ5> , <http://purl.uniprot.org/uniprot/A0A7I2V5J4> ;
        foaf:page           <http://www.uniprot.org/uniprot/Q15136> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/f3725>
        rdf:type            wp:Interaction , wp:Binding , wp:DirectedInteraction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/29997323> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/f3725> ;
        wp:participants     <https://identifiers.org/chebi/CHEBI:18332> , <https://identifiers.org/uniprot/P36021> ;
        wp:source           <https://identifiers.org/chebi/CHEBI:18332> ;
        wp:target           <https://identifiers.org/uniprot/P36021> .

<https://identifiers.org/ensembl/ENSG00000132170>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "PPARG" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000132170> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000132170" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Complex/e9b9c> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000132170> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/5468> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/PPARG> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/E9PFV2> , <https://identifiers.org/uniprot/A0A494C012> , <https://identifiers.org/uniprot/A0A499FIV4> , <https://identifiers.org/uniprot/A0A804HIG1> , <https://identifiers.org/uniprot/A0A494C0T3> , <https://identifiers.org/uniprot/E7EU07> , <https://identifiers.org/uniprot/E9PFV3> , <https://identifiers.org/uniprot/A0A804HJN2> , <https://identifiers.org/uniprot/A0A494C0D9> , <https://identifiers.org/uniprot/A0A3P3ZKM0> , <https://identifiers.org/uniprot/A0A804HLH1> , <https://identifiers.org/uniprot/P37231> , <https://identifiers.org/uniprot/E9PFX5> , <https://identifiers.org/uniprot/A0A804HL89> , <https://identifiers.org/uniprot/Q6L9M1> , <https://identifiers.org/uniprot/E7EUD1> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q20970208> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/e11e4> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/E9PFX5> , <http://purl.uniprot.org/uniprot/A0A499FIV4> , <http://purl.uniprot.org/uniprot/A0A804HL89> , <http://purl.uniprot.org/uniprot/A0A804HLH1> , <http://purl.uniprot.org/uniprot/P37231> , <http://purl.uniprot.org/uniprot/E9PFV2> , <http://purl.uniprot.org/uniprot/A0A804HJN2> , <http://purl.uniprot.org/uniprot/E9PFV3> , <http://purl.uniprot.org/uniprot/E7EU07> , <http://purl.uniprot.org/uniprot/A0A494C0T3> , <http://purl.uniprot.org/uniprot/A0A494C012> , <http://purl.uniprot.org/uniprot/A0A494C0D9> , <http://purl.uniprot.org/uniprot/A0A804HIG1> , <http://purl.uniprot.org/uniprot/A0A3P3ZKM0> , <http://purl.uniprot.org/uniprot/Q6L9M1> , <http://purl.uniprot.org/uniprot/E7EUD1> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000132170> .

<https://doi.org/10.1016%2FS0092-8674%2800%2980405-5>
        dc:source           "DOI" ;
        dcterms:identifier  "10.1016/S0092-8674(00)80405-5" .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/bfea0>
        rdf:type            wp:Stimulation , wp:Interaction , wp:DirectedInteraction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/24872083> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/bfea0> ;
        wp:participants     <https://identifiers.org/uniprot/Q15136> , <https://identifiers.org/ensembl/ENSG00000135540> ;
        wp:source           <https://identifiers.org/uniprot/Q15136> ;
        wp:target           <https://identifiers.org/ensembl/ENSG00000135540> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/ComplexBinding/ee028>
        rdf:type          wp:ComplexBinding , wp:Binding , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4746_r140519> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Group/ee028> ;
        wp:participants   <https://identifiers.org/uniprot/P10827> , <https://identifiers.org/chebi/CHEBI:18258> , <https://identifiers.org/ensembl/ENSG00000186350> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Complex/ee028> .

<https://identifiers.org/ensembl/ENSG00000115966>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "ATF2" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000115966> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000115966" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/f0352> , <https://identifiers.org/wikipathways/WP4746_r140519> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/e0070> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/d0a5e> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/e64f6> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000115966> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/1386> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/ATF2> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/E9PEK8> , <https://identifiers.org/uniprot/F2Z2K2> , <https://identifiers.org/uniprot/P15336> , <https://identifiers.org/uniprot/C9JCI8> , <https://identifiers.org/uniprot/H7C2N6> , <https://identifiers.org/uniprot/B8ZZU6> , <https://identifiers.org/uniprot/E9PBF9> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q4677462> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/b0886> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/H7C2N6> , <http://purl.uniprot.org/uniprot/B8ZZU6> , <http://purl.uniprot.org/uniprot/C9JCI8> , <http://purl.uniprot.org/uniprot/F2Z2K2> , <http://purl.uniprot.org/uniprot/E9PBF9> , <http://purl.uniprot.org/uniprot/E9PEK8> , <http://purl.uniprot.org/uniprot/P15336> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000115966> .

<https://identifiers.org/ensembl/ENSG00000122585>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "NPY" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000122585> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000122585" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Complex/dddea> , <https://identifiers.org/wikipathways/WP4746_r140519> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000122585> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/4852> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/NPY> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/P01303> , <https://identifiers.org/uniprot/A4D158> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q14864369> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/b9331> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P01303> , <http://purl.uniprot.org/uniprot/A4D158> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000122585> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/cdb49>
        rdf:type          wp:Binding , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4746_r140519> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/cdb49> ;
        wp:participants   <https://identifiers.org/uniprot/P36021> , <https://identifiers.org/chebi/CHEBI:18258> ;
        wp:source         <https://identifiers.org/chebi/CHEBI:18258> ;
        wp:target         <https://identifiers.org/uniprot/P36021> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/fad79>
        rdf:type            wp:Stimulation , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/17666482> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/fad79> ;
        wp:participants     <https://identifiers.org/chebi/CHEBI:16595> , <https://identifiers.org/uniprot/A0A087WT80> ;
        wp:source           <https://identifiers.org/uniprot/A0A087WT80> ;
        wp:target           <https://identifiers.org/chebi/CHEBI:16595> .

<https://identifiers.org/ensembl/ENSG00000009765>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "IYD" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000009765> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000009765" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/d7286> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/d2bcd> , <https://identifiers.org/wikipathways/WP4746_r140519> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000009765> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/389434> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/IYD> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/H7C0X6> , <https://identifiers.org/uniprot/C9JXJ9> , <https://identifiers.org/uniprot/Q6PHW0> , <https://identifiers.org/uniprot/F6VN83> , <https://identifiers.org/uniprot/F5H543> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q4342226> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/a6065> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/H7C0X6> , <http://purl.uniprot.org/uniprot/C9JXJ9> , <http://purl.uniprot.org/uniprot/F5H543> , <http://purl.uniprot.org/uniprot/F6VN83> , <http://purl.uniprot.org/uniprot/Q6PHW0> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000009765> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/c39e7>
        rdf:type          wp:Conversion , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4746_r140519> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/c39e7> ;
        wp:participants   <https://identifiers.org/chebi/CHEBI:89575> , <https://identifiers.org/chebi/CHEBI:18258> ;
        wp:source         <https://identifiers.org/chebi/CHEBI:18258> ;
        wp:target         <https://identifiers.org/chebi/CHEBI:89575> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/f3bf4>
        rdf:type            wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/20167242> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/f3bf4> ;
        wp:participants     <https://identifiers.org/chebi/CHEBI:16382> , <https://identifiers.org/chebi/CHEBI:23796> ;
        wp:source           <https://identifiers.org/chebi/CHEBI:23796> ;
        wp:target           <https://identifiers.org/chebi/CHEBI:16382> .

<https://doi.org/10.1038%2FNCB839>
        dc:source           "DOI" ;
        dcterms:identifier  "10.1038/NCB839" .

<https://identifiers.org/chebi/CHEBI:35366>
        rdf:type            wp:DataNode , wp:Metabolite ;
        rdfs:label          "FFA" ;
        dc:identifier       <https://identifiers.org/chebi/CHEBI:35366> ;
        dc:source           "ChEBI" ;
        dcterms:identifier  "CHEBI:35366" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/fd422> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/b6ec1> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:35366> ;
        wp:bdbKeggCompound  <https://identifiers.org/kegg.compound/C00162> ;
        wp:bdbLipidMaps     <https://identifiers.org/lipidmaps/LMFA01010000> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q61476> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/f869e> ;
        owl:sameAs          <https://www.lipidmaps.org/rdf/LMFA01010000> ;
        foaf:page           <https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:35366> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/be36b>
        rdf:type            wp:Interaction , wp:DirectedInteraction , wp:Binding ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/23045339> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/be36b> ;
        wp:participants     <https://identifiers.org/ensembl/ENSG00000112394> , <https://identifiers.org/chebi/CHEBI:18258> ;
        wp:source           <https://identifiers.org/chebi/CHEBI:18258> ;
        wp:target           <https://identifiers.org/ensembl/ENSG00000112394> .

<https://identifiers.org/ensembl/ENSG00000123104>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "IP3R" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000123104> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000123104" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/bb990> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/eaf92> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/c194f> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/a6959> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000123104> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/3709> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/ITPR2> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q14571> , <https://identifiers.org/uniprot/H7C2X9> , <https://identifiers.org/uniprot/F5GYT5> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18028076> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/ce6ba> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/f872b> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/H7C2X9> , <http://purl.uniprot.org/uniprot/F5GYT5> , <http://purl.uniprot.org/uniprot/Q14571> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000123104> .

<https://identifiers.org/ensembl/ENSG00000132906>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "CASP9" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000132906> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000132906" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/daf19> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/ae922> , <https://identifiers.org/wikipathways/WP4746_r140519> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000132906> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/842> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/CASP9> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/H0Y3S8> , <https://identifiers.org/uniprot/Q5JRU8> , <https://identifiers.org/uniprot/F8VWA5> , <https://identifiers.org/uniprot/Q5JRU2> , <https://identifiers.org/uniprot/H0Y6Y2> , <https://identifiers.org/uniprot/A0A087WX72> , <https://identifiers.org/uniprot/P55211> , <https://identifiers.org/uniprot/F8VVS7> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q14907714> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/b5a7f> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q5JRU8> , <http://purl.uniprot.org/uniprot/H0Y3S8> , <http://purl.uniprot.org/uniprot/H0Y6Y2> , <http://purl.uniprot.org/uniprot/F8VWA5> , <http://purl.uniprot.org/uniprot/P55211> , <http://purl.uniprot.org/uniprot/F8VVS7> , <http://purl.uniprot.org/uniprot/A0A087WX72> , <http://purl.uniprot.org/uniprot/Q5JRU2> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000132906> .

<https://identifiers.org/ensembl/ENSG00000204673>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "PRAS40" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000204673> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000204673" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000204673> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/84335> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/AKT1S1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/M0R2V8> , <https://identifiers.org/uniprot/H9KV91> , <https://identifiers.org/uniprot/A0A024QZF6> , <https://identifiers.org/uniprot/Q96B36> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18047581> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/e5f4c> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A024QZF6> , <http://purl.uniprot.org/uniprot/Q96B36> , <http://purl.uniprot.org/uniprot/H9KV91> , <http://purl.uniprot.org/uniprot/M0R2V8> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000204673> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/d3591>
        rdf:type          wp:Stimulation , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4746_r140519> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/d3591> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000135540> , <https://identifiers.org/ensembl/ENSG00000166819> ;
        wp:source         <https://identifiers.org/ensembl/ENSG00000166819> ;
        wp:target         <https://identifiers.org/ensembl/ENSG00000135540> .

<https://identifiers.org/ensembl/ENSG00000150907>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "FOXO1" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000150907> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000150907" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/b15ce> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/c65ca> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000150907> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/2308> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/FOXO1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q12778> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q17928793> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/cb74d> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q12778> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000150907> .

<https://identifiers.org/uniprot/P36021>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "MCT8" ;
        dc:identifier       <https://identifiers.org/uniprot/P36021> ;
        dc:source           "UniProtKB" ;
        dcterms:identifier  "P36021" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/e90a1> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/b9e72> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/bf6ae> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/d1c5b> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/fea96> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/c0740> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/a146f> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/b8bcd> , <https://identifiers.org/wikipathways/WP4746_r140519> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/b7bb2> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/f3725> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/d86d8> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/fa968> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/fa15b> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/cbdc8> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/cdb49> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/e64a3> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/b0d4d> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000147100> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/6567> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/SLC16A2> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/P36021> , <https://identifiers.org/uniprot/K7ELT4> , <https://identifiers.org/uniprot/A0A1B0GVB4> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/dcd9a> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/a1357> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/a172c> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/c500c> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/e9320> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/c942a> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/a0f2c> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/ad0f9> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/K7ELT4> , <http://purl.uniprot.org/uniprot/P36021> , <http://purl.uniprot.org/uniprot/A0A1B0GVB4> ;
        foaf:page           <http://www.uniprot.org/uniprot/P36021> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/e0070>
        rdf:type            wp:Interaction , wp:DirectedInteraction , wp:Stimulation ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/21317437> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/e0070> ;
        wp:participants     <https://identifiers.org/ensembl/ENSG00000115966> , <https://identifiers.org/ensembl/ENSG00000105550> ;
        wp:source           <https://identifiers.org/ensembl/ENSG00000115966> ;
        wp:target           <https://identifiers.org/ensembl/ENSG00000105550> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/ComplexBinding/c5bc4>
        rdf:type          wp:ComplexBinding , wp:Binding , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4746_r140519> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Group/c5bc4> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000077782> , <https://identifiers.org/ensembl/ENSG00000134962> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Complex/c5bc4> .

<http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/d437f>
        rdf:type            wp:Interaction , wp:Binding , wp:DirectedInteraction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4746_r140519> ;
        dcterms:references  <https://identifiers.org/pubmed/15964803> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/Interaction/d437f> ;
        wp:participants     <https://identifiers.org/chebi/CHEBI:17489> , <https://identifiers.org/uniprot/Q15136> ;
        wp:source           <https://identifiers.org/chebi/CHEBI:17489> ;
        wp:target           <https://identifiers.org/uniprot/Q15136> .

<https://identifiers.org/pubmed/28235572>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "28235572" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/aad88> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/e1b11> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/28235572> .

<https://identifiers.org/uniprot/A0A0K0K1K3>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "AC" ;
        dc:identifier       <https://identifiers.org/uniprot/A0A0K0K1K3> ;
        dc:source           "UniProtKB" ;
        dcterms:identifier  "A0A0K0K1K3" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/ee727> , <https://identifiers.org/wikipathways/WP4746_r140519> , <http://rdf.wikipathways.org/Pathway/WP4746_r140519/WP/Interaction/f2651> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000155897> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/114> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/ADCY8> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A0K0K1K3> , <https://identifiers.org/uniprot/E7EVL1> , <https://identifiers.org/uniprot/E5RFR2> , <https://identifiers.org/uniprot/P40145> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4746_r140519/DataNode/e1b50> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A0K0K1K3> , <http://purl.uniprot.org/uniprot/E7EVL1> , <http://purl.uniprot.org/uniprot/P40145> , <http://purl.uniprot.org/uniprot/E5RFR2> ;
        foaf:page           <http://www.uniprot.org/uniprot/A0A0K0K1K3> .
