@prefix biopax:  <http://www.biopax.org/release/biopax-level3.owl#> .
@prefix cito:    <http://purl.org/spar/cito/> .
@prefix dc:      <http://purl.org/dc/elements/1.1/> .
@prefix dcterms: <http://purl.org/dc/terms/> .
@prefix foaf:    <http://xmlns.com/foaf/0.1/> .
@prefix freq:    <http://purl.org/cld/freq/> .
@prefix gpml:    <http://vocabularies.wikipathways.org/gpml#> .
@prefix obo:     <http://purl.obolibrary.org/obo/> .
@prefix owl:     <http://www.w3.org/2002/07/owl#> .
@prefix pav:     <http://purl.org/pav/> .
@prefix prov:    <http://www.w3.org/ns/prov#> .
@prefix rdf:     <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix rdfs:    <http://www.w3.org/2000/01/rdf-schema#> .
@prefix skos:    <http://www.w3.org/2004/02/skos/core#> .
@prefix void:    <http://rdfs.org/ns/void#> .
@prefix wp:      <http://vocabularies.wikipathways.org/wp#> .
@prefix wprdf:   <http://rdf.wikipathways.org/> .
@prefix xsd:     <http://www.w3.org/2001/XMLSchema#> .

<https://identifiers.org/wikipathways/WP4313>
        rdf:type            wp:Pathway , wp:DataNode ;
        rdfs:label          "Ferroptosis" ;
        dc:identifier       <https://identifiers.org/wikipathways/WP4313> ;
        dc:source           "WikiPathways" ;
        dcterms:identifier  "WP4313" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4914_r140858> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4914_r140858/DataNode/da35a> ;
        foaf:page           <https://www.wikipathways.org/instance/WP4313> .

<https://identifiers.org/wikipathways/WP4914>
        pav:hasVersion  <https://identifiers.org/wikipathways/WP4914_r140858> .

<https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=png&pwTitle=Pathway:WP4914&oldid=140858>
        rdf:type        foaf:Image ;
        dcterms:format  "image/png" .

<https://identifiers.org/wikipathways/WP4923>
        rdf:type            wp:Pathway , wp:DataNode ;
        rdfs:label          "Autophagy" ;
        dc:identifier       <https://identifiers.org/wikipathways/WP4923> ;
        dc:source           "WikiPathways" ;
        dcterms:identifier  "WP4923" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4914_r140858> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4914_r140858/DataNode/a32fb> ;
        foaf:page           <https://www.wikipathways.org/instance/WP4923> .

<https://identifiers.org/chebi/CHEBI:4357>
        rdf:type            wp:Metabolite , wp:DataNode ;
        rdfs:label          "Deguelin" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/ORDAZKGHSNRHTD-UXHICEINSA-N> ;
        dc:identifier       <https://identifiers.org/chebi/CHEBI:4357> ;
        dc:source           "ChEBI" ;
        dcterms:identifier  "CHEBI:4357" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4914_r140858> , <http://rdf.wikipathways.org/Pathway/WP4914_r140858/WP/Interaction/idf6c24cf3> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:4357> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/97058> ;
        wp:bdbHmdb          <https://identifiers.org/hmdb/HMDB0302647> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/ORDAZKGHSNRHTD-UXHICEINSA-N> ;
        wp:bdbKeggCompound  <https://identifiers.org/kegg.compound/C10417> ;
        wp:bdbLipidMaps     <https://identifiers.org/lipidmaps/LMPK12060019> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID107935> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q5251862> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4914_r140858/DataNode/c4845> ;
        owl:sameAs          <https://www.lipidmaps.org/rdf/LMPK12060019> ;
        foaf:page           <https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:4357> .

<https://identifiers.org/wikipathways/WP5022>
        rdf:type            wp:Pathway , wp:DataNode ;
        rdfs:label          "Necrosis" ;
        dc:identifier       <https://identifiers.org/wikipathways/WP5022> ;
        dc:source           "WikiPathways" ;
        dcterms:identifier  "WP5022" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4914_r140858> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4914_r140858/DataNode/b849e> ;
        foaf:page           <https://www.wikipathways.org/instance/WP5022> .

<https://identifiers.org/wikipathways/WP4919>
        rdf:type            wp:Pathway , wp:DataNode ;
        rdfs:label          "Neuroinflammation" ;
        dc:identifier       <https://identifiers.org/wikipathways/WP4919> ;
        dc:source           "WikiPathways" ;
        dcterms:identifier  "WP4919" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4914_r140858> , <http://rdf.wikipathways.org/Pathway/WP4914_r140858/WP/Interaction/idf7526463_2> , <http://rdf.wikipathways.org/Pathway/WP4914_r140858/WP/Interaction/idf7526463_1> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4914_r140858/DataNode/e21ed> ;
        foaf:page           <https://www.wikipathways.org/instance/WP4919> .

<https://identifiers.org/wikipathways/WP2855>
        rdf:type            wp:Pathway , wp:DataNode ;
        rdfs:label          "Degeneration of DA neurons  of nigrostratial pathway" ;
        dc:identifier       <https://identifiers.org/wikipathways/WP2855> ;
        dc:source           "WikiPathways" ;
        dcterms:identifier  "WP2855" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4914_r140858/WP/Interaction/idf7526463_2> , <https://identifiers.org/wikipathways/WP4914_r140858> , <http://rdf.wikipathways.org/Pathway/WP4914_r140858/WP/Interaction/idf7526463_1> , <http://rdf.wikipathways.org/Pathway/WP4914_r140858/WP/Interaction/idb9a7d5a> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4914_r140858/DataNode/c2234> ;
        foaf:page           <https://www.wikipathways.org/instance/WP2855> .

<http://rdf.wikipathways.org/Pathway/WP4914_r140858/WP/Interaction/idb9a7d5a>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4914_r140858> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4914_r140858/Interaction/idb9a7d5a> ;
        wp:participants   <https://identifiers.org/wikipathways/WP2371> , <https://identifiers.org/wikipathways/WP2855> ;
        wp:source         <https://identifiers.org/wikipathways/WP2855> ;
        wp:target         <https://identifiers.org/wikipathways/WP2371> .

<http://rdf.wikipathways.org/Pathway/WP4914_r140858/WP/Interaction/id453b8772>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4914_r140858> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4914_r140858/Interaction/id453b8772> ;
        wp:participants   <https://identifiers.org/wikipathways/WP4925> , <https://identifiers.org/wikipathways/WP4918> ;
        wp:source         <https://identifiers.org/wikipathways/WP4918> ;
        wp:target         <https://identifiers.org/wikipathways/WP4925> .

<https://identifiers.org/wikipathways/WP4918>
        rdf:type            wp:DataNode , wp:Pathway ;
        rdfs:label          "Impaired proteostasis" ;
        dc:identifier       <https://identifiers.org/wikipathways/WP4918> ;
        dc:source           "WikiPathways" ;
        dcterms:identifier  "WP4918" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4914_r140858/WP/Interaction/id453b8772> , <https://identifiers.org/wikipathways/WP4914_r140858> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4914_r140858/DataNode/f0306> ;
        foaf:page           <https://www.wikipathways.org/instance/WP4918> .

<https://identifiers.org/wikipathways/WP2371>
        rdf:type            wp:Pathway , wp:DataNode ;
        rdfs:label          "Parkinsonian motor deficits" ;
        dc:identifier       <https://identifiers.org/wikipathways/WP2371> ;
        dc:source           "WikiPathways" ;
        dcterms:identifier  "WP2371" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4914_r140858/WP/Interaction/idb9a7d5a> , <https://identifiers.org/wikipathways/WP4914_r140858> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4914_r140858/DataNode/c99b3> ;
        foaf:page           <https://www.wikipathways.org/instance/WP2371> .

<http://rdf.wikipathways.org/Pathway/WP4914_r140858/WP/Interaction/id2efc1a5d>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4914_r140858> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4914_r140858/Interaction/id2efc1a5d> ;
        wp:participants   <https://identifiers.org/wikipathways/WP4324> , <https://identifiers.org/chebi/CHEBI:28201> ;
        wp:source         <https://identifiers.org/chebi/CHEBI:28201> ;
        wp:target         <https://identifiers.org/wikipathways/WP4324> .

<https://identifiers.org/wikipathways/WP4917>
        rdf:type            wp:Pathway , wp:DataNode ;
        rdfs:label          "Decreased proximal tubule vectorial transport" ;
        dc:identifier       <https://identifiers.org/wikipathways/WP4917> ;
        dc:source           "WikiPathways" ;
        dcterms:identifier  "WP4917" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4914_r140858> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4914_r140858/DataNode/c8280> ;
        foaf:page           <https://www.wikipathways.org/instance/WP4917> .

<https://identifiers.org/wikipathways/WP3941>
        rdf:type            wp:Pathway , wp:DataNode ;
        rdfs:label          "Increased ROS" ;
        dc:identifier       <https://identifiers.org/wikipathways/WP3941> ;
        dc:source           "WikiPathways" ;
        dcterms:identifier  "WP3941" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4914_r140858> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4914_r140858/DataNode/ee94d> ;
        foaf:page           <https://www.wikipathways.org/instance/WP3941> .

<https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=svg&pwTitle=Pathway:WP4914&oldid=140858>
        rdf:type        foaf:Image ;
        dcterms:format  "image/svg+xml" .

<https://identifiers.org/chebi/CHEBI:28201>
        rdf:type            wp:DataNode , wp:Metabolite ;
        rdfs:label          "Rotenone" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/JUVIOZPCNVVQFO-HBGVWJBISA-N> , <https://identifiers.org/inchikey/XPWRIXBORAHMCD-UHFFFAOYSA-N> ;
        dc:identifier       <https://identifiers.org/chebi/CHEBI:28201> ;
        dc:source           "ChEBI" ;
        dcterms:identifier  "CHEBI:28201" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4914_r140858> , <http://rdf.wikipathways.org/Pathway/WP4914_r140858/WP/Interaction/id2efc1a5d> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:28201> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/6500> ;
        wp:bdbHmdb          <https://identifiers.org/hmdb/HMDB0034436> , <https://identifiers.org/hmdb/HMDB0036799> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/XPWRIXBORAHMCD-UHFFFAOYSA-N> , <https://identifiers.org/inchikey/JUVIOZPCNVVQFO-HBGVWJBISA-N> ;
        wp:bdbKeggCompound  <https://identifiers.org/kegg.compound/C07593> ;
        wp:bdbLipidMaps     <https://identifiers.org/lipidmaps/LMPK12060007> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID6758> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q412388> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4914_r140858/DataNode/ff5c5> ;
        owl:sameAs          <https://www.lipidmaps.org/rdf/LMPK12060007> ;
        foaf:page           <https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:28201> .

<https://identifiers.org/wikipathways/WP4925>
        rdf:type            wp:Pathway , wp:DataNode ;
        rdfs:label          "UPR" ;
        dc:identifier       <https://identifiers.org/wikipathways/WP4925> ;
        dc:source           "WikiPathways" ;
        dcterms:identifier  "WP4925" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4914_r140858> , <http://rdf.wikipathways.org/Pathway/WP4914_r140858/WP/Interaction/id453b8772> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4914_r140858/DataNode/f9989> ;
        foaf:page           <https://www.wikipathways.org/instance/WP4925> .

<https://identifiers.org/wikipathways/WP4914_r140858>
        rdf:type               wp:Pathway , skos:Collection ;
        dc:identifier          <https://identifiers.org/wikipathways/WP4914> ;
        dc:source              "WikiPathways" ;
        dc:title               "Adverse outcome pathway for mitochondrial complex 1 (C1) inhibition"@en ;
        dcterms:description    "Adverse Outcome Pathway (AOP) network for mitochondrial Complex 1 (C1) inhibition leading to adverse outcomes in kidney, brain and liver.\nAdverse Outcome Pathways (AOPs), in general, are defined as a sequence of key events that begins with a molecular initiating event (MIE) and leads to an Adverse Outcome. At that level, AOPs are described in the [AOPWiki](https://aopwiki.org/). This AOP network is based on 3 AOPs: [AOPwiki:3](https://aopwiki.org/aops/3), [AOPwiki:273](https://aopwiki.org/aops/273) and [AOPwiki:276](https://aopwiki.org/aops/276)." ;
        dcterms:identifier     "WP4914" ;
        wp:diseaseOntologyTag  obo:DOID_14330 , obo:DOID_0090066 ;
        wp:isAbout             <http://rdf.wikipathways.org/Pathway/WP4914_r140858> ;
        wp:ontologyTag         obo:PW_0000023 , wp:Curation:AnalysisCollection , obo:DOID_14330 , wp:Curation:ONTOX , wp:Curation:AOP , obo:DOID_0090066 , obo:PW_0001118 ;
        wp:organism            obo:NCBITaxon_9606 ;
        wp:organismName        "Homo sapiens" ;
        wp:pathwayOntologyTag  obo:PW_0001118 , obo:PW_0000023 ;
        foaf:img               <https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=png&pwTitle=Pathway:WP4914&oldid=140858> , <https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=svg&pwTitle=Pathway:WP4914&oldid=140858> ;
        foaf:page              <http://www.wikipathways.org/instance/WP4914_r140858> .

<https://identifiers.org/wikipathways/WP4324>
        rdf:type            wp:Pathway , wp:DataNode ;
        rdfs:label          "Inhibition of mitochondrial Complex I" ;
        dc:identifier       <https://identifiers.org/wikipathways/WP4324> ;
        dc:source           "WikiPathways" ;
        dcterms:identifier  "WP4324" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4914_r140858/WP/Interaction/id2efc1a5d> , <http://rdf.wikipathways.org/Pathway/WP4914_r140858/WP/Interaction/idf6c24cf3> , <https://identifiers.org/wikipathways/WP4914_r140858> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4914_r140858/DataNode/e9c7d> ;
        foaf:page           <https://www.wikipathways.org/instance/WP4324> .

obo:NCBITaxon_9606  obo:NCIT_C179773  "9606" .

<http://rdf.wikipathways.org/Pathway/WP4914_r140858/WP/Interaction/idf7526463_2>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4914_r140858> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4914_r140858/Interaction/idf7526463> ;
        wp:participants   <https://identifiers.org/wikipathways/WP4919> , <https://identifiers.org/wikipathways/WP2855> ;
        wp:source         <https://identifiers.org/wikipathways/WP4919> ;
        wp:target         <https://identifiers.org/wikipathways/WP2855> .

<https://identifiers.org/wikipathways/WP111>
        rdf:type            wp:Pathway , wp:DataNode ;
        rdfs:label          "Decreased mitochondrial oxidative phosphorylation" ;
        dc:identifier       <https://identifiers.org/wikipathways/WP111> ;
        dc:source           "WikiPathways" ;
        dcterms:identifier  "WP111" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4914_r140858> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4914_r140858/DataNode/c850d> ;
        foaf:page           <https://www.wikipathways.org/instance/WP111> .

<http://rdf.wikipathways.org/Pathway/WP4914_r140858/WP/Interaction/idf6c24cf3>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4914_r140858> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4914_r140858/Interaction/idf6c24cf3> ;
        wp:participants   <https://identifiers.org/wikipathways/WP4324> , <https://identifiers.org/chebi/CHEBI:4357> ;
        wp:source         <https://identifiers.org/chebi/CHEBI:4357> ;
        wp:target         <https://identifiers.org/wikipathways/WP4324> .

<http://rdf.wikipathways.org/Pathway/WP4914_r140858/WP/Interaction/idf7526463_1>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4914_r140858> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4914_r140858/Interaction/idf7526463> ;
        wp:participants   <https://identifiers.org/wikipathways/WP4919> , <https://identifiers.org/wikipathways/WP2855> ;
        wp:source         <https://identifiers.org/wikipathways/WP2855> ;
        wp:target         <https://identifiers.org/wikipathways/WP4919> .

<https://identifiers.org/wikipathways/WP1772>
        rdf:type            wp:Pathway , wp:DataNode ;
        rdfs:label          "Apoptosis" ;
        dc:identifier       <https://identifiers.org/wikipathways/WP1772> ;
        dc:source           "WikiPathways" ;
        dcterms:identifier  "WP1772" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4914_r140858> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4914_r140858/DataNode/d4c18> ;
        foaf:page           <https://www.wikipathways.org/instance/WP1772> .
