@prefix biopax:  <http://www.biopax.org/release/biopax-level3.owl#> .
@prefix cito:    <http://purl.org/spar/cito/> .
@prefix dc:      <http://purl.org/dc/elements/1.1/> .
@prefix dcterms: <http://purl.org/dc/terms/> .
@prefix foaf:    <http://xmlns.com/foaf/0.1/> .
@prefix freq:    <http://purl.org/cld/freq/> .
@prefix gpml:    <http://vocabularies.wikipathways.org/gpml#> .
@prefix obo:     <http://purl.obolibrary.org/obo/> .
@prefix owl:     <http://www.w3.org/2002/07/owl#> .
@prefix pav:     <http://purl.org/pav/> .
@prefix prov:    <http://www.w3.org/ns/prov#> .
@prefix rdf:     <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix rdfs:    <http://www.w3.org/2000/01/rdf-schema#> .
@prefix skos:    <http://www.w3.org/2004/02/skos/core#> .
@prefix void:    <http://rdfs.org/ns/void#> .
@prefix wp:      <http://vocabularies.wikipathways.org/wp#> .
@prefix wprdf:   <http://rdf.wikipathways.org/> .
@prefix xsd:     <http://www.w3.org/2001/XMLSchema#> .

<http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/e2d6b>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2374_r137995> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2374_r137995/Interaction/e2d6b> ;
        wp:participants   <https://identifiers.org/ncbigene/3265> , <https://identifiers.org/ncbigene/6654> ;
        wp:source         <https://identifiers.org/ncbigene/6654> ;
        wp:target         <https://identifiers.org/ncbigene/3265> .

<https://identifiers.org/ncbigene/5594>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "MAPK1" ;
        dc:identifier       <https://identifiers.org/ncbigene/5594> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "5594" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/b0a67> , <http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/af527> , <http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/eb8ac> , <https://identifiers.org/wikipathways/WP2374_r137995> , <http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/d9c37> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000100030> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/5594> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/MAPK1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q1HBJ4> , <https://identifiers.org/uniprot/P28482> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2374_r137995/DataNode/a43bb> , <http://rdf.wikipathways.org/Pathway/WP2374_r137995/DataNode/fccd5> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P28482> , <http://purl.uniprot.org/uniprot/Q1HBJ4> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/5594> .

<https://identifiers.org/pmc/PMC12174437>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed Central" ;
        dcterms:identifier  "PMC12174437" ;
        cito:cites          <https://identifiers.org/wikipathways/WP2374> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/PMC12174437> .

<http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/f8a05>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2374_r137995> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2374_r137995/Interaction/f8a05> ;
        wp:participants   <https://identifiers.org/ncbigene/3491> , <https://identifiers.org/ncbigene/5970> ;
        wp:source         <https://identifiers.org/ncbigene/5970> ;
        wp:target         <https://identifiers.org/ncbigene/3491> .

<http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/fd987>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2374_r137995> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2374_r137995/Interaction/fd987> ;
        wp:participants   <https://identifiers.org/ncbigene/3717> , <https://identifiers.org/ncbigene/3572> ;
        wp:source         <https://identifiers.org/ncbigene/3572> ;
        wp:target         <https://identifiers.org/ncbigene/3717> .

<https://identifiers.org/pubmed/16459330>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "16459330" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2374_r137995> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/16459330> .

<https://identifiers.org/ncbigene/3716>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "JAK1" ;
        dc:identifier       <https://identifiers.org/ncbigene/3716> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "3716" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/d2dd5> , <http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/cb214> , <http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/a8894> , <http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/daac1> , <http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/idf7c4d4b8> , <https://identifiers.org/wikipathways/WP2374_r137995> , <http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/id2d32c46f> , <http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/d91d1> , <http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/ee28a> , <http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/ed0da> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000162434> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/3716> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/JAK1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A8V8TN11> , <https://identifiers.org/uniprot/A0A5F9ZI01> , <https://identifiers.org/uniprot/A0A8V8TN56> , <https://identifiers.org/uniprot/A0A5F9ZHN8> , <https://identifiers.org/uniprot/A0A5F9ZHI1> , <https://identifiers.org/uniprot/A0A5F9ZH73> , <https://identifiers.org/uniprot/P23458> , <https://identifiers.org/uniprot/A0A8V8TPG3> , <https://identifiers.org/uniprot/A0A5F9ZH07> , <https://identifiers.org/uniprot/A0A8V8TPQ9> , <https://identifiers.org/uniprot/A0A5F9ZHW0> , <https://identifiers.org/uniprot/A0A8V8TMY8> , <https://identifiers.org/uniprot/A0A0A0N0M2> , <https://identifiers.org/uniprot/A0A5F9ZI39> , <https://identifiers.org/uniprot/A0A5F9ZHK2> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2374_r137995/DataNode/d344d> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A8V8TPQ9> , <http://purl.uniprot.org/uniprot/A0A8V8TN11> , <http://purl.uniprot.org/uniprot/A0A5F9ZI01> , <http://purl.uniprot.org/uniprot/A0A5F9ZH07> , <http://purl.uniprot.org/uniprot/A0A8V8TN56> , <http://purl.uniprot.org/uniprot/A0A5F9ZHI1> , <http://purl.uniprot.org/uniprot/A0A0A0N0M2> , <http://purl.uniprot.org/uniprot/A0A5F9ZHN8> , <http://purl.uniprot.org/uniprot/A0A5F9ZHW0> , <http://purl.uniprot.org/uniprot/A0A5F9ZHK2> , <http://purl.uniprot.org/uniprot/A0A5F9ZH73> , <http://purl.uniprot.org/uniprot/P23458> , <http://purl.uniprot.org/uniprot/A0A8V8TPG3> , <http://purl.uniprot.org/uniprot/A0A5F9ZI39> , <http://purl.uniprot.org/uniprot/A0A8V8TMY8> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/3716> .

<http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/daac1>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2374_r137995> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2374_r137995/Interaction/daac1> ;
        wp:participants   <https://identifiers.org/ncbigene/1432> , <https://identifiers.org/ncbigene/3716> ;
        wp:source         <https://identifiers.org/ncbigene/3716> ;
        wp:target         <https://identifiers.org/ncbigene/1432> .

<https://identifiers.org/ncbigene/5581>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "PRKCE" ;
        dc:identifier       <https://identifiers.org/ncbigene/5581> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "5581" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2374_r137995> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000171132> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/5581> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/PRKCE> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/E9PBI2> , <https://identifiers.org/uniprot/C9JR22> , <https://identifiers.org/uniprot/L7RTI5> , <https://identifiers.org/uniprot/Q02156> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2374_r137995/DataNode/b750e> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/C9JR22> , <http://purl.uniprot.org/uniprot/Q02156> , <http://purl.uniprot.org/uniprot/E9PBI2> , <http://purl.uniprot.org/uniprot/L7RTI5> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/5581> .

<http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/d0c0c>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2374_r137995> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2374_r137995/Interaction/d0c0c> ;
        wp:participants   <https://identifiers.org/ncbigene/3572> , <https://identifiers.org/ncbigene/3717> ;
        wp:source         <https://identifiers.org/ncbigene/3717> ;
        wp:target         <https://identifiers.org/ncbigene/3572> .

<https://identifiers.org/ncbigene/5894>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "RAF1" ;
        dc:identifier       <https://identifiers.org/ncbigene/5894> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "5894" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2374_r137995> , <http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/d2dd5> , <http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/a90a6> , <http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/e8e93> , <http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/e0994> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000132155> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/5894> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/RAF1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A8I5KS16> , <https://identifiers.org/uniprot/A0A0S2Z559> , <https://identifiers.org/uniprot/A0A8I5KWA9> , <https://identifiers.org/uniprot/A0A8I5KSV6> , <https://identifiers.org/uniprot/A0A8I5KQV4> , <https://identifiers.org/uniprot/A0A8I5KSB0> , <https://identifiers.org/uniprot/A0A8I5KYP5> , <https://identifiers.org/uniprot/A0A8I5KTK4> , <https://identifiers.org/uniprot/A0A8I5KSM4> , <https://identifiers.org/uniprot/P04049> , <https://identifiers.org/uniprot/A0A8I5KT32> , <https://identifiers.org/uniprot/A0A0B4J1W9> , <https://identifiers.org/uniprot/A0A8I5QKU8> , <https://identifiers.org/uniprot/A0A8I5KWS9> , <https://identifiers.org/uniprot/A0A8I5KUW4> , <https://identifiers.org/uniprot/A0A8I5KQ33> , <https://identifiers.org/uniprot/A0A8I5KX50> , <https://identifiers.org/uniprot/A0A8I5QKZ6> , <https://identifiers.org/uniprot/A0A8I5KWF7> , <https://identifiers.org/uniprot/H7C155> , <https://identifiers.org/uniprot/A0A8I5KRD1> , <https://identifiers.org/uniprot/A0A8I5KYC4> , <https://identifiers.org/uniprot/A0A0S2Z4L5> , <https://identifiers.org/uniprot/A0A8I5QJG5> , <https://identifiers.org/uniprot/A0A8I5KW44> , <https://identifiers.org/uniprot/L7RRS6> , <https://identifiers.org/uniprot/A0A8I5KTA5> , <https://identifiers.org/uniprot/A0A8I5KR46> , <https://identifiers.org/uniprot/A0A8I5KSI1> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2374_r137995/DataNode/e86f0> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A8I5QKU8> , <http://purl.uniprot.org/uniprot/A0A0S2Z4L5> , <http://purl.uniprot.org/uniprot/A0A0B4J1W9> , <http://purl.uniprot.org/uniprot/A0A8I5KT32> , <http://purl.uniprot.org/uniprot/A0A8I5KS16> , <http://purl.uniprot.org/uniprot/A0A8I5KTA5> , <http://purl.uniprot.org/uniprot/A0A0S2Z559> , <http://purl.uniprot.org/uniprot/L7RRS6> , <http://purl.uniprot.org/uniprot/A0A8I5KYC4> , <http://purl.uniprot.org/uniprot/A0A8I5QJG5> , <http://purl.uniprot.org/uniprot/A0A8I5KSI1> , <http://purl.uniprot.org/uniprot/H7C155> , <http://purl.uniprot.org/uniprot/A0A8I5KWF7> , <http://purl.uniprot.org/uniprot/P04049> , <http://purl.uniprot.org/uniprot/A0A8I5KUW4> , <http://purl.uniprot.org/uniprot/A0A8I5KWA9> , <http://purl.uniprot.org/uniprot/A0A8I5KSM4> , <http://purl.uniprot.org/uniprot/A0A8I5KSV6> , <http://purl.uniprot.org/uniprot/A0A8I5KQ33> , <http://purl.uniprot.org/uniprot/A0A8I5QKZ6> , <http://purl.uniprot.org/uniprot/A0A8I5KQV4> , <http://purl.uniprot.org/uniprot/A0A8I5KTK4> , <http://purl.uniprot.org/uniprot/A0A8I5KR46> , <http://purl.uniprot.org/uniprot/A0A8I5KSB0> , <http://purl.uniprot.org/uniprot/A0A8I5KW44> , <http://purl.uniprot.org/uniprot/A0A8I5KYP5> , <http://purl.uniprot.org/uniprot/A0A8I5KX50> , <http://purl.uniprot.org/uniprot/A0A8I5KWS9> , <http://purl.uniprot.org/uniprot/A0A8I5KRD1> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/5894> .

<http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/d18a3>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2374_r137995> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2374_r137995/Interaction/d18a3> ;
        wp:participants   <https://identifiers.org/ncbigene/6774> ;
        wp:source         <https://identifiers.org/ncbigene/6774> ;
        wp:target         <https://identifiers.org/ncbigene/6774> .

<https://identifiers.org/wikipathways/WP2374>
        pav:hasVersion  <https://identifiers.org/wikipathways/WP2374_r137995> .

<http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/b2259>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2374_r137995> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2374_r137995/Interaction/b2259> ;
        wp:participants   <https://identifiers.org/ncbigene/5781> , <https://identifiers.org/ncbigene/3572> ;
        wp:source         <https://identifiers.org/ncbigene/3572> ;
        wp:target         <https://identifiers.org/ncbigene/5781> .

<https://identifiers.org/ncbigene/6774>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "STAT3" ;
        dc:identifier       <https://identifiers.org/ncbigene/6774> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "6774" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/c1912> , <http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/ebc24> , <http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/bb6c3> , <http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/d18a3> , <http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/ide9ae73cb> , <http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/c2280> , <https://identifiers.org/wikipathways/WP2374_r137995> , <http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/b0d38> , <http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/dd2df> , <http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/bd195> , <http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/id2a132160> , <http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/id2d32c46f> , <http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/ccceb> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000168610> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/6774> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/STAT3> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A7I2V4F6> , <https://identifiers.org/uniprot/A0A7I2YQI1> , <https://identifiers.org/uniprot/A0A7I2V2T1> , <https://identifiers.org/uniprot/A0A7I2V3V0> , <https://identifiers.org/uniprot/A0A7I2V4R2> , <https://identifiers.org/uniprot/A0A7I2V395> , <https://identifiers.org/uniprot/A0A7I2V5N9> , <https://identifiers.org/uniprot/P40763> , <https://identifiers.org/uniprot/A0A7I2V444> , <https://identifiers.org/uniprot/A0A7I2V4C8> , <https://identifiers.org/uniprot/A0A7I2V4R3> , <https://identifiers.org/uniprot/A0A7I2V552> , <https://identifiers.org/uniprot/A0A7I2YQR5> , <https://identifiers.org/uniprot/A0A7I2V2G1> , <https://identifiers.org/uniprot/G8JLH9> , <https://identifiers.org/uniprot/A0A7I2YQD2> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2374_r137995/DataNode/cec8f> , <http://rdf.wikipathways.org/Pathway/WP2374_r137995/DataNode/c357b> , <http://rdf.wikipathways.org/Pathway/WP2374_r137995/DataNode/b7a85> , <http://rdf.wikipathways.org/Pathway/WP2374_r137995/DataNode/a5326> , <http://rdf.wikipathways.org/Pathway/WP2374_r137995/DataNode/b823f> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A7I2YQI1> , <http://purl.uniprot.org/uniprot/P40763> , <http://purl.uniprot.org/uniprot/A0A7I2V5N9> , <http://purl.uniprot.org/uniprot/G8JLH9> , <http://purl.uniprot.org/uniprot/A0A7I2V4R3> , <http://purl.uniprot.org/uniprot/A0A7I2V3V0> , <http://purl.uniprot.org/uniprot/A0A7I2V4F6> , <http://purl.uniprot.org/uniprot/A0A7I2V444> , <http://purl.uniprot.org/uniprot/A0A7I2V395> , <http://purl.uniprot.org/uniprot/A0A7I2V2T1> , <http://purl.uniprot.org/uniprot/A0A7I2V4R2> , <http://purl.uniprot.org/uniprot/A0A7I2YQR5> , <http://purl.uniprot.org/uniprot/A0A7I2V552> , <http://purl.uniprot.org/uniprot/A0A7I2V4C8> , <http://purl.uniprot.org/uniprot/A0A7I2V2G1> , <http://purl.uniprot.org/uniprot/A0A7I2YQD2> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/6774> .

<https://identifiers.org/ncbigene/4312>
        rdf:type            wp:Rna , wp:DataNode ;
        rdfs:label          "MMP1" ;
        dc:identifier       <https://identifiers.org/ncbigene/4312> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "4312" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2374_r137995> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000196611> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/4312> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/MMP1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/P03956> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2374_r137995/DataNode/d5e62> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P03956> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/4312> .

<https://identifiers.org/ncbigene/5781>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "PTPN11" ;
        dc:identifier       <https://identifiers.org/ncbigene/5781> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "5781" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2374_r137995> , <http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/b2259> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000179295> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/5781> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/PTPN11> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A8I5KW48> , <https://identifiers.org/uniprot/A0A0U1RRI0> , <https://identifiers.org/uniprot/A0A8I5QJ58> , <https://identifiers.org/uniprot/A0A8I5KVS6> , <https://identifiers.org/uniprot/A0A8I5QL30> , <https://identifiers.org/uniprot/A0A8I5KRZ3> , <https://identifiers.org/uniprot/A0A1W2PPU4> , <https://identifiers.org/uniprot/H0YF12> , <https://identifiers.org/uniprot/Q06124> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2374_r137995/DataNode/f7424> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A8I5QJ58> , <http://purl.uniprot.org/uniprot/H0YF12> , <http://purl.uniprot.org/uniprot/Q06124> , <http://purl.uniprot.org/uniprot/A0A8I5KVS6> , <http://purl.uniprot.org/uniprot/A0A1W2PPU4> , <http://purl.uniprot.org/uniprot/A0A0U1RRI0> , <http://purl.uniprot.org/uniprot/A0A8I5KRZ3> , <http://purl.uniprot.org/uniprot/A0A8I5KW48> , <http://purl.uniprot.org/uniprot/A0A8I5QL30> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/5781> .

<https://identifiers.org/ncbigene/3845>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "KRAS" ;
        dc:identifier       <https://identifiers.org/ncbigene/3845> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "3845" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2374_r137995> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000133703> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/3845> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/KRAS> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A8I5KQ21> , <https://identifiers.org/uniprot/A0A8I5KYH6> , <https://identifiers.org/uniprot/P01116> , <https://identifiers.org/uniprot/A0A8I5KUB5> , <https://identifiers.org/uniprot/A0A8I5KXN3> , <https://identifiers.org/uniprot/A0A8I5KR86> , <https://identifiers.org/uniprot/A0A8I5KQU3> , <https://identifiers.org/uniprot/G3V4K2> , <https://identifiers.org/uniprot/A0A024RAV5> , <https://identifiers.org/uniprot/L7RSL8> , <https://identifiers.org/uniprot/G3V5T7> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2374_r137995/DataNode/c1e05> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A8I5KYH6> , <http://purl.uniprot.org/uniprot/A0A8I5KR86> , <http://purl.uniprot.org/uniprot/A0A024RAV5> , <http://purl.uniprot.org/uniprot/A0A8I5KQU3> , <http://purl.uniprot.org/uniprot/G3V5T7> , <http://purl.uniprot.org/uniprot/L7RSL8> , <http://purl.uniprot.org/uniprot/G3V4K2> , <http://purl.uniprot.org/uniprot/A0A8I5KQ21> , <http://purl.uniprot.org/uniprot/A0A8I5KXN3> , <http://purl.uniprot.org/uniprot/P01116> , <http://purl.uniprot.org/uniprot/A0A8I5KUB5> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/3845> .

<https://identifiers.org/ncbigene/836>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "CASP3" ;
        dc:identifier       <https://identifiers.org/ncbigene/836> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "836" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2374_r137995> , <http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/fd1e0> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000164305> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/836> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/CASP3> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A8MVM1> , <https://identifiers.org/uniprot/A0A8V8TPU5> , <https://identifiers.org/uniprot/P42574> , <https://identifiers.org/uniprot/C9JXR7> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2374_r137995/DataNode/eecb8> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P42574> , <http://purl.uniprot.org/uniprot/C9JXR7> , <http://purl.uniprot.org/uniprot/A8MVM1> , <http://purl.uniprot.org/uniprot/A0A8V8TPU5> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/836> .

<https://identifiers.org/pubmed/18430728>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "18430728" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2374_r137995> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/18430728> .

<https://identifiers.org/ncbigene/7078>
        rdf:type            wp:Rna , wp:DataNode ;
        rdfs:label          "TIMP3" ;
        dc:identifier       <https://identifiers.org/ncbigene/7078> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "7078" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2374_r137995> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000100234> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/7078> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/TIMP3> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/P35625> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2374_r137995/DataNode/a179e> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P35625> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/7078> .

<https://identifiers.org/pubmed/18927239>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "18927239" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2374_r137995> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/18927239> .

<http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/c9ab0>
        rdf:type          wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2374_r137995> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2374_r137995/Interaction/c9ab0> .

<https://identifiers.org/ncbigene/7157>
        rdf:type            wp:Rna , wp:DataNode ;
        rdfs:label          "TP53" ;
        dc:identifier       <https://identifiers.org/ncbigene/7157> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "7157" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2374_r137995> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000141510> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/7157> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/TP53> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A087X1Q1> , <https://identifiers.org/uniprot/S4R334> , <https://identifiers.org/uniprot/E9PFT5> , <https://identifiers.org/uniprot/E7EMR6> , <https://identifiers.org/uniprot/A0A087WT22> , <https://identifiers.org/uniprot/K7PPA8> , <https://identifiers.org/uniprot/A0A0U1RQC9> , <https://identifiers.org/uniprot/I3L0W9> , <https://identifiers.org/uniprot/E7ESS1> , <https://identifiers.org/uniprot/E9PCY9> , <https://identifiers.org/uniprot/E7EQX7> , <https://identifiers.org/uniprot/H2EHT1> , <https://identifiers.org/uniprot/J3KP33> , <https://identifiers.org/uniprot/P04637> , <https://identifiers.org/uniprot/A0A087WXZ1> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2374_r137995/DataNode/f6fb5> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/H2EHT1> , <http://purl.uniprot.org/uniprot/A0A0U1RQC9> , <http://purl.uniprot.org/uniprot/S4R334> , <http://purl.uniprot.org/uniprot/E7EMR6> , <http://purl.uniprot.org/uniprot/K7PPA8> , <http://purl.uniprot.org/uniprot/E9PCY9> , <http://purl.uniprot.org/uniprot/P04637> , <http://purl.uniprot.org/uniprot/A0A087WXZ1> , <http://purl.uniprot.org/uniprot/A0A087WT22> , <http://purl.uniprot.org/uniprot/E7ESS1> , <http://purl.uniprot.org/uniprot/A0A087X1Q1> , <http://purl.uniprot.org/uniprot/J3KP33> , <http://purl.uniprot.org/uniprot/E7EQX7> , <http://purl.uniprot.org/uniprot/I3L0W9> , <http://purl.uniprot.org/uniprot/E9PFT5> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/7157> .

<https://identifiers.org/ncbigene/5605>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "MAP2K2" ;
        dc:identifier       <https://identifiers.org/ncbigene/5605> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "5605" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2374_r137995> , <http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/d9c37> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000126934> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/5605> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/MAP2K2> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/M0R1B6> , <https://identifiers.org/uniprot/P36507> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2374_r137995/DataNode/eb5c9> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/M0R1B6> , <http://purl.uniprot.org/uniprot/P36507> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/5605> .

<https://identifiers.org/ncbigene/5008>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "OSM" ;
        dc:identifier       <https://identifiers.org/ncbigene/5008> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "5008" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/b79e8> , <https://identifiers.org/wikipathways/WP2374_r137995> , <http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/c97c2> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000099985> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/5008> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/OSM> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/B5MCX1> , <https://identifiers.org/uniprot/B5MC70> , <https://identifiers.org/uniprot/P13725> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2374_r137995/DataNode/e01b2> , <http://rdf.wikipathways.org/Pathway/WP2374_r137995/DataNode/c58d1> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/B5MCX1> , <http://purl.uniprot.org/uniprot/B5MC70> , <http://purl.uniprot.org/uniprot/P13725> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/5008> .

<http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/a4e18>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2374_r137995> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2374_r137995/Interaction/a4e18> ;
        wp:participants   <https://identifiers.org/ncbigene/6654> , <https://identifiers.org/ncbigene/2885> ;
        wp:source         <https://identifiers.org/ncbigene/2885> ;
        wp:target         <https://identifiers.org/ncbigene/6654> .

<https://identifiers.org/ncbigene/9021>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "SOCS3" ;
        dc:identifier       <https://identifiers.org/ncbigene/9021> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "9021" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2374_r137995> , <http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/cb214> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000184557> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/9021> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/SOCS3> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/O14543> , <https://identifiers.org/uniprot/K7EIF6> , <https://identifiers.org/uniprot/Q6FI39> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2374_r137995/DataNode/ae77e> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q6FI39> , <http://purl.uniprot.org/uniprot/O14543> , <http://purl.uniprot.org/uniprot/K7EIF6> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/9021> .

<https://identifiers.org/pubmed/11038252>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "11038252" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2374_r137995> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/11038252> .

<http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/b0531>
        rdf:type          wp:TranscriptionTranslation , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2374_r137995> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2374_r137995/Interaction/b0531> ;
        wp:participants   <https://identifiers.org/ncbigene/3491> , <https://identifiers.org/ncbigene/1385> ;
        wp:source         <https://identifiers.org/ncbigene/1385> ;
        wp:target         <https://identifiers.org/ncbigene/3491> .

<https://identifiers.org/pubmed/10356359>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "10356359" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2374_r137995> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/10356359> .

<http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/b7e73>
        rdf:type          wp:TranscriptionTranslation , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2374_r137995> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2374_r137995/Interaction/b7e73> ;
        wp:participants   <https://identifiers.org/ncbigene/5054> , <https://identifiers.org/ncbigene/3727> ;
        wp:source         <https://identifiers.org/ncbigene/3727> ;
        wp:target         <https://identifiers.org/ncbigene/5054> .

<http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/ed0da>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2374_r137995> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2374_r137995/Interaction/ed0da> ;
        wp:participants   <https://identifiers.org/ncbigene/5599> , <https://identifiers.org/ncbigene/3716> ;
        wp:source         <https://identifiers.org/ncbigene/3716> ;
        wp:target         <https://identifiers.org/ncbigene/5599> .

<https://identifiers.org/pmc/PMC12470172>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed Central" ;
        dcterms:identifier  "PMC12470172" ;
        cito:cites          <https://identifiers.org/wikipathways/WP2374> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/PMC12470172> .

<http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/b0247>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2374_r137995> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2374_r137995/Interaction/b0247> ;
        wp:participants   <https://identifiers.org/ncbigene/1958> , <https://identifiers.org/ncbigene/1051> ;
        wp:source         <https://identifiers.org/ncbigene/1051> ;
        wp:target         <https://identifiers.org/ncbigene/1958> .

<https://identifiers.org/ncbigene/6464>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "SHC1" ;
        dc:identifier       <https://identifiers.org/ncbigene/6464> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "6464" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2374_r137995> , <http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/add52> , <http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/be230> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000160691> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/6464> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/SHC1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q5T187> , <https://identifiers.org/uniprot/H0Y539> , <https://identifiers.org/uniprot/P29353> , <https://identifiers.org/uniprot/Q5T181> , <https://identifiers.org/uniprot/X6R6D0> , <https://identifiers.org/uniprot/Q5T188> , <https://identifiers.org/uniprot/Q5T182> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2374_r137995/DataNode/b75d3> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q5T182> , <http://purl.uniprot.org/uniprot/X6R6D0> , <http://purl.uniprot.org/uniprot/Q5T187> , <http://purl.uniprot.org/uniprot/H0Y539> , <http://purl.uniprot.org/uniprot/P29353> , <http://purl.uniprot.org/uniprot/Q5T188> , <http://purl.uniprot.org/uniprot/Q5T181> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/6464> .

<http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/c2280>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2374_r137995> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2374_r137995/Interaction/c2280> ;
        wp:participants   <https://identifiers.org/ncbigene/5970> , <https://identifiers.org/ncbigene/6774> ;
        wp:source         <https://identifiers.org/ncbigene/6774> ;
        wp:target         <https://identifiers.org/ncbigene/5970> .

<http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/id2a132160>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2374_r137995> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2374_r137995/Interaction/id2a132160> ;
        wp:participants   <https://identifiers.org/ncbigene/6774> ;
        wp:source         <https://identifiers.org/ncbigene/6774> ;
        wp:target         <https://identifiers.org/ncbigene/6774> .

<https://identifiers.org/ncbigene/6777>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "STAT5B" ;
        dc:identifier       <https://identifiers.org/ncbigene/6777> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "6777" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/ea7b2> , <https://identifiers.org/wikipathways/WP2374_r137995> , <http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/b1365> , <http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/a8894> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000173757> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/6777> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/STAT5B> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A8V8TMP4> , <https://identifiers.org/uniprot/A0A8V8TP21> , <https://identifiers.org/uniprot/A0A8V8TM91> , <https://identifiers.org/uniprot/A0A8V8TMR0> , <https://identifiers.org/uniprot/A0A8V8TP00> , <https://identifiers.org/uniprot/A0A8V8TMQ6> , <https://identifiers.org/uniprot/A0A8V8TMA6> , <https://identifiers.org/uniprot/P51692> , <https://identifiers.org/uniprot/A0A8V8TM84> , <https://identifiers.org/uniprot/A0A8V8TP16> , <https://identifiers.org/uniprot/C9J4I3> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2374_r137995/DataNode/c2def> , <http://rdf.wikipathways.org/Pathway/WP2374_r137995/DataNode/f562e> , <http://rdf.wikipathways.org/Pathway/WP2374_r137995/DataNode/edf2d> , <http://rdf.wikipathways.org/Pathway/WP2374_r137995/DataNode/f8a75> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A8V8TMR0> , <http://purl.uniprot.org/uniprot/A0A8V8TP00> , <http://purl.uniprot.org/uniprot/C9J4I3> , <http://purl.uniprot.org/uniprot/A0A8V8TMA6> , <http://purl.uniprot.org/uniprot/A0A8V8TMQ6> , <http://purl.uniprot.org/uniprot/A0A8V8TP21> , <http://purl.uniprot.org/uniprot/A0A8V8TMP4> , <http://purl.uniprot.org/uniprot/A0A8V8TP16> , <http://purl.uniprot.org/uniprot/P51692> , <http://purl.uniprot.org/uniprot/A0A8V8TM84> , <http://purl.uniprot.org/uniprot/A0A8V8TM91> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/6777> .

<https://identifiers.org/ncbigene/3727>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "JUND" ;
        dc:identifier       <https://identifiers.org/ncbigene/3727> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "3727" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/b7e73> , <https://identifiers.org/wikipathways/WP2374_r137995> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000130522> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/3727> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/JUND> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/U3KPR5> , <https://identifiers.org/uniprot/P17535> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2374_r137995/DataNode/eaf83> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/U3KPR5> , <http://purl.uniprot.org/uniprot/P17535> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/3727> .

<https://identifiers.org/ensembl/ENSG00000112715>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "VEGFA" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000112715> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000112715" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2374_r137995> , <http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/b0a67> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000112715> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/7422> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/VEGFA> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/H0YBI8> , <https://identifiers.org/uniprot/A0A0A0MSH5> , <https://identifiers.org/uniprot/J3KPA4> , <https://identifiers.org/uniprot/A0A0A0MTB2> , <https://identifiers.org/uniprot/A0A0Y0IMM4> , <https://identifiers.org/uniprot/H3BLW8> , <https://identifiers.org/uniprot/A0A0A0MR43> , <https://identifiers.org/uniprot/P15692> , <https://identifiers.org/uniprot/A2A2V4> , <https://identifiers.org/uniprot/A0A024RD33> , <https://identifiers.org/uniprot/A0A5F9ZH41> , <https://identifiers.org/uniprot/A0A0A0MSI7> , <https://identifiers.org/uniprot/A0A024RD37> , <https://identifiers.org/uniprot/H0YBZ0> , <https://identifiers.org/uniprot/A0A0A0MSH7> , <https://identifiers.org/uniprot/A0A0A0MRQ4> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18032324> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2374_r137995/DataNode/e5901> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/J3KPA4> , <http://purl.uniprot.org/uniprot/A0A024RD33> , <http://purl.uniprot.org/uniprot/H3BLW8> , <http://purl.uniprot.org/uniprot/A0A5F9ZH41> , <http://purl.uniprot.org/uniprot/A0A0A0MTB2> , <http://purl.uniprot.org/uniprot/H0YBZ0> , <http://purl.uniprot.org/uniprot/A0A0A0MSH5> , <http://purl.uniprot.org/uniprot/A2A2V4> , <http://purl.uniprot.org/uniprot/A0A0A0MRQ4> , <http://purl.uniprot.org/uniprot/A0A0A0MR43> , <http://purl.uniprot.org/uniprot/A0A0A0MSI7> , <http://purl.uniprot.org/uniprot/A0A0A0MSH7> , <http://purl.uniprot.org/uniprot/P15692> , <http://purl.uniprot.org/uniprot/A0A0Y0IMM4> , <http://purl.uniprot.org/uniprot/A0A024RD37> , <http://purl.uniprot.org/uniprot/H0YBI8> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000112715> .

<http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/e0994>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2374_r137995> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2374_r137995/Interaction/e0994> ;
        wp:participants   <https://identifiers.org/ncbigene/5894> , <https://identifiers.org/ncbigene/7297> ;
        wp:source         <https://identifiers.org/ncbigene/7297> ;
        wp:target         <https://identifiers.org/ncbigene/5894> .

<https://identifiers.org/ncbigene/6714>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "SRC" ;
        dc:identifier       <https://identifiers.org/ncbigene/6714> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "6714" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/ee28a> , <https://identifiers.org/wikipathways/WP2374_r137995> , <http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/dd2df> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000197122> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/6714> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/SRC> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A8I5KYU4> , <https://identifiers.org/uniprot/P12931> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2374_r137995/DataNode/aa147> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P12931> , <http://purl.uniprot.org/uniprot/A0A8I5KYU4> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/6714> .

<http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/c4332>
        rdf:type          wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2374_r137995> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2374_r137995/Interaction/c4332> .

<http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/fb11b>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2374_r137995> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2374_r137995/Interaction/fb11b> ;
        wp:participants   <https://identifiers.org/ncbigene/5295> , <https://identifiers.org/ncbigene/3718> ;
        wp:source         <https://identifiers.org/ncbigene/3718> ;
        wp:target         <https://identifiers.org/ncbigene/5295> .

<http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/a90a6>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2374_r137995> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2374_r137995/Interaction/a90a6> ;
        wp:participants   <https://identifiers.org/ncbigene/5604> , <https://identifiers.org/ncbigene/5894> ;
        wp:source         <https://identifiers.org/ncbigene/5894> ;
        wp:target         <https://identifiers.org/ncbigene/5604> .

<https://identifiers.org/ncbigene/5579>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "PRKCB" ;
        dc:identifier       <https://identifiers.org/ncbigene/5579> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "5579" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2374_r137995> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000166501> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/5579> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/PRKCB> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/I3L148> , <https://identifiers.org/uniprot/I3L1Z0> , <https://identifiers.org/uniprot/H3BV73> , <https://identifiers.org/uniprot/P05771> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2374_r137995/DataNode/a84f6> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/I3L148> , <http://purl.uniprot.org/uniprot/I3L1Z0> , <http://purl.uniprot.org/uniprot/P05771> , <http://purl.uniprot.org/uniprot/H3BV73> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/5579> .

<http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/f18c5>
        rdf:type          wp:TranscriptionTranslation , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2374_r137995> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2374_r137995/Interaction/f18c5> ;
        wp:participants   <https://identifiers.org/ncbigene/3949> , <https://identifiers.org/ncbigene/1958> ;
        wp:source         <https://identifiers.org/ncbigene/1958> ;
        wp:target         <https://identifiers.org/ncbigene/3949> .

<http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/b79e8>
        rdf:type          wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2374_r137995> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2374_r137995/Interaction/b79e8> ;
        wp:participants   <https://identifiers.org/ncbigene/5008> .

<http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/d8743>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2374_r137995> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2374_r137995/Interaction/d8743> ;
        wp:participants   <https://identifiers.org/ncbigene/5829> , <https://identifiers.org/ncbigene/2185> ;
        wp:source         <https://identifiers.org/ncbigene/2185> ;
        wp:target         <https://identifiers.org/ncbigene/5829> .

<https://identifiers.org/ncbigene/3977>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "LIFR" ;
        dc:identifier       <https://identifiers.org/ncbigene/3977> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "3977" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2374_r137995> , <http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/ca531> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000113594> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/3977> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/LIFR> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/D6RJ94> , <https://identifiers.org/uniprot/D6RF33> , <https://identifiers.org/uniprot/H0YAF2> , <https://identifiers.org/uniprot/P42702> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2374_r137995/DataNode/f7983> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/D6RJ94> , <http://purl.uniprot.org/uniprot/P42702> , <http://purl.uniprot.org/uniprot/H0YAF2> , <http://purl.uniprot.org/uniprot/D6RF33> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/3977> .

<https://identifiers.org/pubmed/11207308>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "11207308" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2374_r137995> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/11207308> .

<https://identifiers.org/ncbigene/3572>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "IL6ST" ;
        dc:identifier       <https://identifiers.org/ncbigene/3572> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "3572" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/ee28a> , <http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/d0c0c> , <http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/b2259> , <http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/fd987> , <http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/d91d1> , <https://identifiers.org/wikipathways/WP2374_r137995> , <http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/f12ab> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000134352> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/3572> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/IL6ST> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q5FC02> , <https://identifiers.org/uniprot/Q5FC05> , <https://identifiers.org/uniprot/A0A8V8TM11> , <https://identifiers.org/uniprot/A0A8V8TNU5> , <https://identifiers.org/uniprot/A0A8V8TMJ4> , <https://identifiers.org/uniprot/Q5FC07> , <https://identifiers.org/uniprot/D6RH03> , <https://identifiers.org/uniprot/A0A494BZU0> , <https://identifiers.org/uniprot/A0A8V8TNI8> , <https://identifiers.org/uniprot/A0A0A0N0L2> , <https://identifiers.org/uniprot/A0A8V8TMJ9> , <https://identifiers.org/uniprot/A0A8V8TNI4> , <https://identifiers.org/uniprot/P40189> , <https://identifiers.org/uniprot/A0A0A0N0L5> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2374_r137995/DataNode/f687e> , <http://rdf.wikipathways.org/Pathway/WP2374_r137995/DataNode/ced2c> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A8V8TNU5> , <http://purl.uniprot.org/uniprot/Q5FC02> , <http://purl.uniprot.org/uniprot/A0A8V8TNI4> , <http://purl.uniprot.org/uniprot/Q5FC07> , <http://purl.uniprot.org/uniprot/A0A494BZU0> , <http://purl.uniprot.org/uniprot/A0A8V8TM11> , <http://purl.uniprot.org/uniprot/A0A8V8TMJ4> , <http://purl.uniprot.org/uniprot/A0A8V8TMJ9> , <http://purl.uniprot.org/uniprot/D6RH03> , <http://purl.uniprot.org/uniprot/A0A0A0N0L2> , <http://purl.uniprot.org/uniprot/A0A8V8TNI8> , <http://purl.uniprot.org/uniprot/P40189> , <http://purl.uniprot.org/uniprot/Q5FC05> , <http://purl.uniprot.org/uniprot/A0A0A0N0L5> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/3572> .

<https://identifiers.org/ncbigene/5829>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "PXN" ;
        dc:identifier       <https://identifiers.org/ncbigene/5829> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "5829" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2374_r137995> , <http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/d8743> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000089159> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/5829> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/PXN> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/F8W0K8> , <https://identifiers.org/uniprot/P49023> , <https://identifiers.org/uniprot/F5H836> , <https://identifiers.org/uniprot/F8W1E0> , <https://identifiers.org/uniprot/A0A140VJQ8> , <https://identifiers.org/uniprot/F5GZ78> , <https://identifiers.org/uniprot/A0A1B0GU60> , <https://identifiers.org/uniprot/F8W0G0> , <https://identifiers.org/uniprot/A0A1B0GV30> , <https://identifiers.org/uniprot/F8VZ39> , <https://identifiers.org/uniprot/A0A1B0GWE7> , <https://identifiers.org/uniprot/A0A1B0GTU4> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2374_r137995/DataNode/e1154> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/F8W1E0> , <http://purl.uniprot.org/uniprot/F5GZ78> , <http://purl.uniprot.org/uniprot/A0A140VJQ8> , <http://purl.uniprot.org/uniprot/F8W0K8> , <http://purl.uniprot.org/uniprot/A0A1B0GV30> , <http://purl.uniprot.org/uniprot/F8VZ39> , <http://purl.uniprot.org/uniprot/A0A1B0GTU4> , <http://purl.uniprot.org/uniprot/F5H836> , <http://purl.uniprot.org/uniprot/P49023> , <http://purl.uniprot.org/uniprot/F8W0G0> , <http://purl.uniprot.org/uniprot/A0A1B0GWE7> , <http://purl.uniprot.org/uniprot/A0A1B0GU60> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/5829> .

<https://identifiers.org/ncbigene/5295>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "PIK3R1" ;
        dc:identifier       <https://identifiers.org/ncbigene/5295> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "5295" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/cd7ab> , <http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/fb11b> , <https://identifiers.org/wikipathways/WP2374_r137995> , <http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/e7b82> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000145675> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/5295> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/PIK3R1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/E5RJY0> , <https://identifiers.org/uniprot/H0YB27> , <https://identifiers.org/uniprot/A0A8V8TME9> , <https://identifiers.org/uniprot/P27986> , <https://identifiers.org/uniprot/A0A8V8TL14> , <https://identifiers.org/uniprot/A0A8V8TL31> , <https://identifiers.org/uniprot/E5RGI8> , <https://identifiers.org/uniprot/A0A8V8TLE6> , <https://identifiers.org/uniprot/A0A8V8TLF1> , <https://identifiers.org/uniprot/B3KWZ7> , <https://identifiers.org/uniprot/E5RHI0> , <https://identifiers.org/uniprot/E5RK66> , <https://identifiers.org/uniprot/A0A8V8TMF4> , <https://identifiers.org/uniprot/A0A8V8TLF7> , <https://identifiers.org/uniprot/A0A8V8TMF9> , <https://identifiers.org/uniprot/A0A8V8TL10> , <https://identifiers.org/uniprot/H0YBC2> , <https://identifiers.org/uniprot/A0A2X0SFG1> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2374_r137995/DataNode/cfd69> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A8V8TMF9> , <http://purl.uniprot.org/uniprot/A0A8V8TME9> , <http://purl.uniprot.org/uniprot/A0A8V8TL14> , <http://purl.uniprot.org/uniprot/A0A8V8TL10> , <http://purl.uniprot.org/uniprot/P27986> , <http://purl.uniprot.org/uniprot/A0A8V8TL31> , <http://purl.uniprot.org/uniprot/H0YBC2> , <http://purl.uniprot.org/uniprot/E5RGI8> , <http://purl.uniprot.org/uniprot/A0A8V8TLE6> , <http://purl.uniprot.org/uniprot/A0A8V8TLF7> , <http://purl.uniprot.org/uniprot/B3KWZ7> , <http://purl.uniprot.org/uniprot/E5RHI0> , <http://purl.uniprot.org/uniprot/A0A2X0SFG1> , <http://purl.uniprot.org/uniprot/H0YB27> , <http://purl.uniprot.org/uniprot/A0A8V8TMF4> , <http://purl.uniprot.org/uniprot/A0A8V8TLF1> , <http://purl.uniprot.org/uniprot/E5RK66> , <http://purl.uniprot.org/uniprot/E5RJY0> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/5295> .

<https://identifiers.org/ncbigene/6772>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "STAT1" ;
        dc:identifier       <https://identifiers.org/ncbigene/6772> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "6772" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/dd384> , <http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/a56be> , <http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/b0d38> , <http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/d723b> , <https://identifiers.org/wikipathways/WP2374_r137995> , <http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/b5f56> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000115415> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/6772> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/STAT1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A669KB56> , <https://identifiers.org/uniprot/J3KPM9> , <https://identifiers.org/uniprot/A0A8V8TMY9> , <https://identifiers.org/uniprot/A0A669KBK4> , <https://identifiers.org/uniprot/A0A8V8TN81> , <https://identifiers.org/uniprot/D2KFR9> , <https://identifiers.org/uniprot/Q67C41> , <https://identifiers.org/uniprot/A0A8V8TLI6> , <https://identifiers.org/uniprot/A0A669KB17> , <https://identifiers.org/uniprot/E9PH66> , <https://identifiers.org/uniprot/P42224> , <https://identifiers.org/uniprot/A0A669KB52> , <https://identifiers.org/uniprot/A0A669KB68> , <https://identifiers.org/uniprot/A0A669KBI6> , <https://identifiers.org/uniprot/E7ENM1> , <https://identifiers.org/uniprot/A0A669KBA4> , <https://identifiers.org/uniprot/A0A669KB53> , <https://identifiers.org/uniprot/E7EPD2> , <https://identifiers.org/uniprot/A0A669KB75> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2374_r137995/DataNode/f8387> , <http://rdf.wikipathways.org/Pathway/WP2374_r137995/DataNode/c7868> , <http://rdf.wikipathways.org/Pathway/WP2374_r137995/DataNode/ffe5c> , <http://rdf.wikipathways.org/Pathway/WP2374_r137995/DataNode/ab0d8> , <http://rdf.wikipathways.org/Pathway/WP2374_r137995/DataNode/d5331> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A8V8TMY9> , <http://purl.uniprot.org/uniprot/Q67C41> , <http://purl.uniprot.org/uniprot/E7ENM1> , <http://purl.uniprot.org/uniprot/A0A669KB52> , <http://purl.uniprot.org/uniprot/A0A669KB56> , <http://purl.uniprot.org/uniprot/A0A669KB75> , <http://purl.uniprot.org/uniprot/A0A669KB68> , <http://purl.uniprot.org/uniprot/A0A669KBI6> , <http://purl.uniprot.org/uniprot/E9PH66> , <http://purl.uniprot.org/uniprot/P42224> , <http://purl.uniprot.org/uniprot/A0A669KB53> , <http://purl.uniprot.org/uniprot/A0A669KB17> , <http://purl.uniprot.org/uniprot/A0A8V8TN81> , <http://purl.uniprot.org/uniprot/E7EPD2> , <http://purl.uniprot.org/uniprot/A0A669KBK4> , <http://purl.uniprot.org/uniprot/J3KPM9> , <http://purl.uniprot.org/uniprot/D2KFR9> , <http://purl.uniprot.org/uniprot/A0A8V8TLI6> , <http://purl.uniprot.org/uniprot/A0A669KBA4> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/6772> .

<http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/cf4c8>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2374_r137995> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2374_r137995/Interaction/cf4c8> ;
        wp:participants   <https://identifiers.org/ncbigene/5970> , <https://identifiers.org/ncbigene/207> ;
        wp:source         <https://identifiers.org/ncbigene/207> ;
        wp:target         <https://identifiers.org/ncbigene/5970> .

<https://identifiers.org/pubmed/21548952>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "21548952" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2374_r137995> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/21548952> .

<https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=png&pwTitle=Pathway:WP2374&oldid=137995>
        rdf:type        foaf:Image ;
        dcterms:format  "image/png" .

<http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/ide9ae73cb>
        rdf:type          wp:Inhibition , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2374_r137995> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2374_r137995/Interaction/ide9ae73cb> ;
        wp:participants   <https://identifiers.org/ncbigene/6774> , <https://identifiers.org/ncbigene/10401> ;
        wp:source         <https://identifiers.org/ncbigene/10401> ;
        wp:target         <https://identifiers.org/ncbigene/6774> .

<https://identifiers.org/ncbigene/5595>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "MAPK3" ;
        dc:identifier       <https://identifiers.org/ncbigene/5595> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "5595" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/f7ad3> , <https://identifiers.org/wikipathways/WP2374_r137995> , <http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/af527> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000102882> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/5595> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/MAPK3> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/E9PQW4> , <https://identifiers.org/uniprot/H0YDH9> , <https://identifiers.org/uniprot/H0YEX6> , <https://identifiers.org/uniprot/B3KR49> , <https://identifiers.org/uniprot/E9PRH7> , <https://identifiers.org/uniprot/L7RXH5> , <https://identifiers.org/uniprot/E9PJF0> , <https://identifiers.org/uniprot/E9PBK7> , <https://identifiers.org/uniprot/P27361> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2374_r137995/DataNode/a50ce> , <http://rdf.wikipathways.org/Pathway/WP2374_r137995/DataNode/ad840> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/E9PBK7> , <http://purl.uniprot.org/uniprot/B3KR49> , <http://purl.uniprot.org/uniprot/L7RXH5> , <http://purl.uniprot.org/uniprot/H0YDH9> , <http://purl.uniprot.org/uniprot/E9PJF0> , <http://purl.uniprot.org/uniprot/E9PQW4> , <http://purl.uniprot.org/uniprot/P27361> , <http://purl.uniprot.org/uniprot/H0YEX6> , <http://purl.uniprot.org/uniprot/E9PRH7> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/5595> .

<http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/ee28a>
        rdf:type          wp:Interaction , wp:DirectedInteraction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2374_r137995> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2374_r137995/Interaction/cf28c> , <http://rdf.wikipathways.org/Pathway/WP2374_r137995/Interaction/ee28a> ;
        wp:participants   <https://identifiers.org/ncbigene/3716> , <https://identifiers.org/ncbigene/3572> , <https://identifiers.org/ncbigene/6714> ;
        wp:source         <https://identifiers.org/ncbigene/3572> ;
        wp:target         <https://identifiers.org/ncbigene/3716> , <https://identifiers.org/ncbigene/6714> .

<https://identifiers.org/ncbigene/7297>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "TYK2" ;
        dc:identifier       <https://identifiers.org/ncbigene/7297> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "7297" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/e0994> , <http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/f12ab> , <https://identifiers.org/wikipathways/WP2374_r137995> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000105397> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/7297> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/TYK2> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A8V8TPX5> , <https://identifiers.org/uniprot/A0A8V8TPJ3> , <https://identifiers.org/uniprot/H0YE24> , <https://identifiers.org/uniprot/A0A8V8TN95> , <https://identifiers.org/uniprot/A0A8V8TPJ0> , <https://identifiers.org/uniprot/P29597> , <https://identifiers.org/uniprot/H0YE41> , <https://identifiers.org/uniprot/H0YCT7> , <https://identifiers.org/uniprot/E9PQE9> , <https://identifiers.org/uniprot/A0A8V8TPH2> , <https://identifiers.org/uniprot/A0A8V8TN50> , <https://identifiers.org/uniprot/K7EM33> , <https://identifiers.org/uniprot/A0A8V8TN89> , <https://identifiers.org/uniprot/E9PM19> , <https://identifiers.org/uniprot/A0A8V8TNM9> , <https://identifiers.org/uniprot/A0A8V8TN55> , <https://identifiers.org/uniprot/K7EJR6> , <https://identifiers.org/uniprot/E9PQL2> , <https://identifiers.org/uniprot/A0A024R7E4> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2374_r137995/DataNode/c588b> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A8V8TPH2> , <http://purl.uniprot.org/uniprot/E9PQL2> , <http://purl.uniprot.org/uniprot/A0A8V8TN89> , <http://purl.uniprot.org/uniprot/A0A8V8TN95> , <http://purl.uniprot.org/uniprot/H0YCT7> , <http://purl.uniprot.org/uniprot/H0YE41> , <http://purl.uniprot.org/uniprot/A0A8V8TPJ3> , <http://purl.uniprot.org/uniprot/P29597> , <http://purl.uniprot.org/uniprot/A0A024R7E4> , <http://purl.uniprot.org/uniprot/A0A8V8TN55> , <http://purl.uniprot.org/uniprot/K7EM33> , <http://purl.uniprot.org/uniprot/A0A8V8TPJ0> , <http://purl.uniprot.org/uniprot/H0YE24> , <http://purl.uniprot.org/uniprot/K7EJR6> , <http://purl.uniprot.org/uniprot/A0A8V8TPX5> , <http://purl.uniprot.org/uniprot/A0A8V8TN50> , <http://purl.uniprot.org/uniprot/A0A8V8TNM9> , <http://purl.uniprot.org/uniprot/E9PM19> , <http://purl.uniprot.org/uniprot/E9PQE9> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/7297> .

<https://identifiers.org/ncbigene/2353>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "FOS" ;
        dc:identifier       <https://identifiers.org/ncbigene/2353> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "2353" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/ab515> , <http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/c1912> , <https://identifiers.org/wikipathways/WP2374_r137995> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000170345> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/2353> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/FOS> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/G3V5N9> , <https://identifiers.org/uniprot/G3V2V7> , <https://identifiers.org/uniprot/Q6FG41> , <https://identifiers.org/uniprot/P01100> , <https://identifiers.org/uniprot/H0YJM3> , <https://identifiers.org/uniprot/G3V5J9> , <https://identifiers.org/uniprot/G3V5N7> , <https://identifiers.org/uniprot/G3V289> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2374_r137995/DataNode/fa965> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/G3V5N7> , <http://purl.uniprot.org/uniprot/G3V2V7> , <http://purl.uniprot.org/uniprot/G3V289> , <http://purl.uniprot.org/uniprot/P01100> , <http://purl.uniprot.org/uniprot/Q6FG41> , <http://purl.uniprot.org/uniprot/H0YJM3> , <http://purl.uniprot.org/uniprot/G3V5J9> , <http://purl.uniprot.org/uniprot/G3V5N9> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/2353> .

<http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/b212e>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2374_r137995> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2374_r137995/Interaction/b212e> ;
        wp:participants   <https://identifiers.org/ncbigene/5970> ;
        wp:source         <https://identifiers.org/ncbigene/5970> ;
        wp:target         <https://identifiers.org/ncbigene/5970> .

<http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/eb8ac>
        rdf:type          wp:TranscriptionTranslation , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2374_r137995> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2374_r137995/Interaction/eb8ac> ;
        wp:participants   <https://identifiers.org/ncbigene/1958> , <https://identifiers.org/ncbigene/5594> ;
        wp:source         <https://identifiers.org/ncbigene/5594> ;
        wp:target         <https://identifiers.org/ncbigene/1958> .

<https://identifiers.org/pubmed/16547273>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "16547273" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2374_r137995> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/16547273> .

<http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/id86ee17e3>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2374_r137995> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2374_r137995/Interaction/id86ee17e3> ;
        wp:participants   <https://identifiers.org/ncbigene/2885> , <https://identifiers.org/ncbigene/3717> ;
        wp:source         <https://identifiers.org/ncbigene/3717> ;
        wp:target         <https://identifiers.org/ncbigene/2885> .

<https://identifiers.org/ncbigene/3717>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "JAK2" ;
        dc:identifier       <https://identifiers.org/ncbigene/3717> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "3717" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2374_r137995> , <http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/fd987> , <http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/ebc24> , <http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/id86ee17e3> , <http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/fd1e0> , <http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/d0c0c> , <http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/be230> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000096968> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/3717> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/JAK2> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/O60674> , <https://identifiers.org/uniprot/A0A1B0GVR5> , <https://identifiers.org/uniprot/A0A1B0GTR9> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2374_r137995/DataNode/c98b7> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A1B0GVR5> , <http://purl.uniprot.org/uniprot/O60674> , <http://purl.uniprot.org/uniprot/A0A1B0GTR9> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/3717> .

<https://identifiers.org/ncbigene/3667>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "IRS1" ;
        dc:identifier       <https://identifiers.org/ncbigene/3667> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "3667" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/idf7c4d4b8> , <https://identifiers.org/wikipathways/WP2374_r137995> , <http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/e7b82> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000169047> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/3667> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/IRS1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/P35568> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2374_r137995/DataNode/d83b9> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P35568> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/3667> .

<http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/b5f56>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2374_r137995> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2374_r137995/Interaction/b5f56> ;
        wp:participants   <https://identifiers.org/ncbigene/6772> ;
        wp:source         <https://identifiers.org/ncbigene/6772> ;
        wp:target         <https://identifiers.org/ncbigene/6772> .

<https://identifiers.org/ncbigene/6654>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "SOS1" ;
        dc:identifier       <https://identifiers.org/ncbigene/6654> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "6654" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/e2d6b> , <http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/a4e18> , <https://identifiers.org/wikipathways/WP2374_r137995> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000115904> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/6654> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/SOS1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A8I5QJF3> , <https://identifiers.org/uniprot/A0A8I5QJ77> , <https://identifiers.org/uniprot/A0A8I5KP47> , <https://identifiers.org/uniprot/C9K0N6> , <https://identifiers.org/uniprot/A0A8I5KWL0> , <https://identifiers.org/uniprot/G5E9C8> , <https://identifiers.org/uniprot/A0A8I5KY52> , <https://identifiers.org/uniprot/A0A8I5KV97> , <https://identifiers.org/uniprot/Q07889> , <https://identifiers.org/uniprot/A0A8I5QJD1> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2374_r137995/DataNode/d460f> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A8I5KP47> , <http://purl.uniprot.org/uniprot/A0A8I5KWL0> , <http://purl.uniprot.org/uniprot/A0A8I5QJD1> , <http://purl.uniprot.org/uniprot/G5E9C8> , <http://purl.uniprot.org/uniprot/A0A8I5QJ77> , <http://purl.uniprot.org/uniprot/A0A8I5QJF3> , <http://purl.uniprot.org/uniprot/Q07889> , <http://purl.uniprot.org/uniprot/C9K0N6> , <http://purl.uniprot.org/uniprot/A0A8I5KY52> , <http://purl.uniprot.org/uniprot/A0A8I5KV97> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/6654> .

<http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/dd2df>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2374_r137995> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2374_r137995/Interaction/dd2df> ;
        wp:participants   <https://identifiers.org/ncbigene/6774> , <https://identifiers.org/ncbigene/6714> ;
        wp:source         <https://identifiers.org/ncbigene/6714> ;
        wp:target         <https://identifiers.org/ncbigene/6774> .

obo:NCBITaxon_9606  obo:NCIT_C179773  "9606" .

<http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/e8e93>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2374_r137995> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2374_r137995/Interaction/e8e93> ;
        wp:participants   <https://identifiers.org/ncbigene/5894> , <https://identifiers.org/ncbigene/3265> ;
        wp:source         <https://identifiers.org/ncbigene/3265> ;
        wp:target         <https://identifiers.org/ncbigene/5894> .

<http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/d90ba>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2374_r137995> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2374_r137995/Interaction/d90ba> ;
        wp:participants   <https://identifiers.org/ncbigene/6194> , <https://identifiers.org/ncbigene/207> ;
        wp:source         <https://identifiers.org/ncbigene/207> ;
        wp:target         <https://identifiers.org/ncbigene/6194> .

<http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/cd7ab>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2374_r137995> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2374_r137995/Interaction/cd7ab> ;
        wp:participants   <https://identifiers.org/ncbigene/207> , <https://identifiers.org/ncbigene/5295> ;
        wp:source         <https://identifiers.org/ncbigene/5295> ;
        wp:target         <https://identifiers.org/ncbigene/207> .

<http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/ebc24>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2374_r137995> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2374_r137995/Interaction/ebc24> ;
        wp:participants   <https://identifiers.org/ncbigene/6774> , <https://identifiers.org/ncbigene/3717> ;
        wp:source         <https://identifiers.org/ncbigene/3717> ;
        wp:target         <https://identifiers.org/ncbigene/6774> .

<http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/a56be>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2374_r137995> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2374_r137995/Interaction/a56be> ;
        wp:participants   <https://identifiers.org/ncbigene/6772> ;
        wp:source         <https://identifiers.org/ncbigene/6772> ;
        wp:target         <https://identifiers.org/ncbigene/6772> .

<https://identifiers.org/pubmed/17471233>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "17471233" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2374_r137995> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/17471233> .

<http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/fd1e0>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2374_r137995> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2374_r137995/Interaction/fd1e0> ;
        wp:participants   <https://identifiers.org/ncbigene/836> , <https://identifiers.org/ncbigene/3717> ;
        wp:source         <https://identifiers.org/ncbigene/3717> ;
        wp:target         <https://identifiers.org/ncbigene/836> .

<https://identifiers.org/ncbigene/3491>
        rdf:type            wp:Rna , wp:DataNode ;
        rdfs:label          "CYR61" ;
        dc:identifier       <https://identifiers.org/ncbigene/3491> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "3491" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/b0531> , <https://identifiers.org/wikipathways/WP2374_r137995> , <http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/f8a05> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000142871> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/3491> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/CCN1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A6Q8PGQ1> , <https://identifiers.org/uniprot/O00622> , <https://identifiers.org/uniprot/Q6FI18> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2374_r137995/DataNode/c50b0> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q6FI18> , <http://purl.uniprot.org/uniprot/O00622> , <http://purl.uniprot.org/uniprot/A0A6Q8PGQ1> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/3491> .

<https://identifiers.org/ncbigene/2185>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "PTK2B" ;
        dc:identifier       <https://identifiers.org/ncbigene/2185> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "2185" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2374_r137995> , <http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/f5b39> , <http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/d8743> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000120899> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/2185> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/PTK2B> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q14289> , <https://identifiers.org/uniprot/E5RJ77> , <https://identifiers.org/uniprot/E5RHL2> , <https://identifiers.org/uniprot/H0YB74> , <https://identifiers.org/uniprot/C9JHV9> , <https://identifiers.org/uniprot/E5RK84> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2374_r137995/DataNode/b50ba> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/C9JHV9> , <http://purl.uniprot.org/uniprot/E5RK84> , <http://purl.uniprot.org/uniprot/H0YB74> , <http://purl.uniprot.org/uniprot/E5RHL2> , <http://purl.uniprot.org/uniprot/E5RJ77> , <http://purl.uniprot.org/uniprot/Q14289> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/2185> .

<https://identifiers.org/pmc/PMC5085087>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed Central" ;
        dcterms:identifier  "PMC5085087" ;
        cito:cites          <https://identifiers.org/wikipathways/WP2374> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/PMC5085087> .

<http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/e7b82>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2374_r137995> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2374_r137995/Interaction/e7b82> ;
        wp:participants   <https://identifiers.org/ncbigene/5295> , <https://identifiers.org/ncbigene/3667> ;
        wp:source         <https://identifiers.org/ncbigene/3667> ;
        wp:target         <https://identifiers.org/ncbigene/5295> .

<https://identifiers.org/pmc/PMC11726005>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed Central" ;
        dcterms:identifier  "PMC11726005" ;
        cito:cites          <https://identifiers.org/wikipathways/WP2374> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/PMC11726005> .

<https://identifiers.org/ncbigene/253260>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "RICTOR" ;
        dc:identifier       <https://identifiers.org/ncbigene/253260> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "253260" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2374_r137995> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000164327> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/253260> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/RICTOR> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/D6R9S6> , <https://identifiers.org/uniprot/Q6R327> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2374_r137995/DataNode/c27e9> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q6R327> , <http://purl.uniprot.org/uniprot/D6R9S6> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/253260> .

<https://doi.org/10.1016%2Fj.humgen.2022.201135>
        rdf:type            wp:PublicationReference ;
        dc:source           "DOI" ;
        dcterms:identifier  "10.1016/j.humgen.2022.201135" ;
        cito:cites          <https://identifiers.org/wikipathways/WP2374> .

<https://identifiers.org/ncbigene/6194>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "RPS6" ;
        dc:identifier       <https://identifiers.org/ncbigene/6194> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "6194" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2374_r137995> , <http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/d90ba> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000137154> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/6194> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/RPS6> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A2A3R5> , <https://identifiers.org/uniprot/P62753> , <https://identifiers.org/uniprot/A2A3R6> , <https://identifiers.org/uniprot/A2A3R7> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2374_r137995/DataNode/f68e0> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A2A3R6> , <http://purl.uniprot.org/uniprot/P62753> , <http://purl.uniprot.org/uniprot/A2A3R5> , <http://purl.uniprot.org/uniprot/A2A3R7> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/6194> .

<http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/f7ad3>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2374_r137995> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2374_r137995/Interaction/f7ad3> ;
        wp:participants   <https://identifiers.org/ncbigene/1051> , <https://identifiers.org/ncbigene/5595> ;
        wp:source         <https://identifiers.org/ncbigene/5595> ;
        wp:target         <https://identifiers.org/ncbigene/1051> .

<http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/f5b39>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2374_r137995> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2374_r137995/Interaction/f5b39> ;
        wp:participants   <https://identifiers.org/ncbigene/2185> , <https://identifiers.org/ncbigene/9180> ;
        wp:source         <https://identifiers.org/ncbigene/9180> ;
        wp:target         <https://identifiers.org/ncbigene/2185> .

<http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/af527>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2374_r137995> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2374_r137995/Interaction/af527> ;
        wp:participants   <https://identifiers.org/ncbigene/5594> , <https://identifiers.org/ncbigene/5595> ;
        wp:source         <https://identifiers.org/ncbigene/5595> ;
        wp:target         <https://identifiers.org/ncbigene/5594> .

<http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/id9cf4b402>
        rdf:type          wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2374_r137995> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2374_r137995/Interaction/id9cf4b402> .

<https://identifiers.org/ncbigene/3265>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "HRAS" ;
        dc:identifier       <https://identifiers.org/ncbigene/3265> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "3265" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/e8e93> , <http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/e2d6b> , <https://identifiers.org/wikipathways/WP2374_r137995> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000174775> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/3265> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/HRAS> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A804HKM6> , <https://identifiers.org/uniprot/A0A804HJ06> , <https://identifiers.org/uniprot/X5D945> , <https://identifiers.org/uniprot/P01112> , <https://identifiers.org/uniprot/A0A8C8MQR2> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2374_r137995/DataNode/abb33> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A8C8MQR2> , <http://purl.uniprot.org/uniprot/X5D945> , <http://purl.uniprot.org/uniprot/P01112> , <http://purl.uniprot.org/uniprot/A0A804HJ06> , <http://purl.uniprot.org/uniprot/A0A804HKM6> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/3265> .

<https://identifiers.org/pubmed/9388184>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "9388184" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2374_r137995> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/9388184> .

<http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/d9c37>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2374_r137995> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2374_r137995/Interaction/d9c37> ;
        wp:participants   <https://identifiers.org/ncbigene/5594> , <https://identifiers.org/ncbigene/5605> ;
        wp:source         <https://identifiers.org/ncbigene/5605> ;
        wp:target         <https://identifiers.org/ncbigene/5594> .

<https://identifiers.org/pubmed/12911774>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "12911774" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2374_r137995> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/12911774> .

<https://identifiers.org/ncbigene/5601>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "MAPK9" ;
        dc:identifier       <https://identifiers.org/ncbigene/5601> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "5601" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2374_r137995> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000050748> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/5601> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/MAPK9> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/P45984> , <https://identifiers.org/uniprot/D7R525> , <https://identifiers.org/uniprot/D7R528> , <https://identifiers.org/uniprot/E5RJ57> , <https://identifiers.org/uniprot/J3KNK1> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2374_r137995/DataNode/b5dd4> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/E5RJ57> , <http://purl.uniprot.org/uniprot/D7R525> , <http://purl.uniprot.org/uniprot/J3KNK1> , <http://purl.uniprot.org/uniprot/P45984> , <http://purl.uniprot.org/uniprot/D7R528> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/5601> .

<https://identifiers.org/ncbigene/4792>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "NFKBIA" ;
        dc:identifier       <https://identifiers.org/ncbigene/4792> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "4792" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/id64fa041c> , <https://identifiers.org/wikipathways/WP2374_r137995> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000100906> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/4792> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/NFKBIA> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/G3V2A2> , <https://identifiers.org/uniprot/G3V286> , <https://identifiers.org/uniprot/G3V3I4> , <https://identifiers.org/uniprot/G3V3K1> , <https://identifiers.org/uniprot/P25963> , <https://identifiers.org/uniprot/A0A8V8TLE7> , <https://identifiers.org/uniprot/A0A8V8TLC3> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2374_r137995/DataNode/a233a> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/G3V286> , <http://purl.uniprot.org/uniprot/P25963> , <http://purl.uniprot.org/uniprot/G3V3K1> , <http://purl.uniprot.org/uniprot/G3V2A2> , <http://purl.uniprot.org/uniprot/A0A8V8TLE7> , <http://purl.uniprot.org/uniprot/A0A8V8TLC3> , <http://purl.uniprot.org/uniprot/G3V3I4> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/4792> .

<https://identifiers.org/ncbigene/840>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "CASP9" , "CASP7" ;
        dc:identifier       <https://identifiers.org/ncbigene/840> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "840" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2374_r137995> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000165806> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/840> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/CASP7> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A5F9ZHZ6> , <https://identifiers.org/uniprot/Q5SVL2> , <https://identifiers.org/uniprot/A0A0A0MRL7> , <https://identifiers.org/uniprot/P55210> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2374_r137995/DataNode/b9557> , <http://rdf.wikipathways.org/Pathway/WP2374_r137995/DataNode/afd61> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P55210> , <http://purl.uniprot.org/uniprot/Q5SVL2> , <http://purl.uniprot.org/uniprot/A0A0A0MRL7> , <http://purl.uniprot.org/uniprot/A0A5F9ZHZ6> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/840> .

<http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/d723b>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2374_r137995> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2374_r137995/Interaction/d723b> ;
        wp:participants   <https://identifiers.org/ncbigene/6772> , <https://identifiers.org/ncbigene/3718> ;
        wp:source         <https://identifiers.org/ncbigene/3718> ;
        wp:target         <https://identifiers.org/ncbigene/6772> .

<https://identifiers.org/ncbigene/3949>
        rdf:type            wp:Rna , wp:DataNode ;
        rdfs:label          "LDLR" ;
        dc:identifier       <https://identifiers.org/ncbigene/3949> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "3949" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/f18c5> , <https://identifiers.org/wikipathways/WP2374_r137995> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000130164> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/3949> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/LDLR> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/H0YM92> , <https://identifiers.org/uniprot/P01130> , <https://identifiers.org/uniprot/H0YMQ3> , <https://identifiers.org/uniprot/H0YMD1> , <https://identifiers.org/uniprot/A0A024R7D5> , <https://identifiers.org/uniprot/J3KMZ9> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2374_r137995/DataNode/e46ec> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/J3KMZ9> , <http://purl.uniprot.org/uniprot/A0A024R7D5> , <http://purl.uniprot.org/uniprot/H0YM92> , <http://purl.uniprot.org/uniprot/P01130> , <http://purl.uniprot.org/uniprot/H0YMD1> , <http://purl.uniprot.org/uniprot/H0YMQ3> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/3949> .

<https://identifiers.org/ncbigene/9180>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "OSMR" ;
        dc:identifier       <https://identifiers.org/ncbigene/9180> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "9180" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2374_r137995> , <http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/f5b39> , <http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/c40e5> , <http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/ea7b2> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000145623> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/9180> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/OSMR> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/H0YAD1> , <https://identifiers.org/uniprot/Q99650> , <https://identifiers.org/uniprot/H0Y8W9> , <https://identifiers.org/uniprot/H0Y9E3> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2374_r137995/DataNode/c3011> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q99650> , <http://purl.uniprot.org/uniprot/H0YAD1> , <http://purl.uniprot.org/uniprot/H0Y8W9> , <http://purl.uniprot.org/uniprot/H0Y9E3> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/9180> .

<https://identifiers.org/ncbigene/5054>
        rdf:type            wp:DataNode , wp:Rna ;
        rdfs:label          "SERPINE1" ;
        dc:identifier       <https://identifiers.org/ncbigene/5054> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "5054" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2374_r137995> , <http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/b7e73> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000106366> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/5054> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/SERPINE1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/P05121> , <https://identifiers.org/uniprot/A0A024QYT5> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2374_r137995/DataNode/cfb48> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P05121> , <http://purl.uniprot.org/uniprot/A0A024QYT5> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/5054> .

<https://identifiers.org/ncbigene/5580>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "PRKCD" ;
        dc:identifier       <https://identifiers.org/ncbigene/5580> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "5580" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2374_r137995> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000163932> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/5580> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/PRKCD> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A8V8TMH8> , <https://identifiers.org/uniprot/C9JZU8> , <https://identifiers.org/uniprot/C9K0E3> , <https://identifiers.org/uniprot/Q05655> , <https://identifiers.org/uniprot/A0A494BZX2> , <https://identifiers.org/uniprot/C9J9P1> , <https://identifiers.org/uniprot/A0A494C1T7> , <https://identifiers.org/uniprot/A0A494C125> , <https://identifiers.org/uniprot/A0A024R328> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2374_r137995/DataNode/fc81f> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/C9JZU8> , <http://purl.uniprot.org/uniprot/A0A024R328> , <http://purl.uniprot.org/uniprot/C9J9P1> , <http://purl.uniprot.org/uniprot/A0A494C1T7> , <http://purl.uniprot.org/uniprot/Q05655> , <http://purl.uniprot.org/uniprot/C9K0E3> , <http://purl.uniprot.org/uniprot/A0A494C125> , <http://purl.uniprot.org/uniprot/A0A494BZX2> , <http://purl.uniprot.org/uniprot/A0A8V8TMH8> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/5580> .

<http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/ca531>
        rdf:type          wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2374_r137995> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2374_r137995/Interaction/ca531> ;
        wp:participants   <https://identifiers.org/ncbigene/3977> .

<https://identifiers.org/ncbigene/2885>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "GRB2" ;
        dc:identifier       <https://identifiers.org/ncbigene/2885> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "2885" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/add52> , <http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/id86ee17e3> , <https://identifiers.org/wikipathways/WP2374_r137995> , <http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/a4e18> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000177885> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/2885> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/GRB2> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/J3KT38> , <https://identifiers.org/uniprot/B0LPF3> , <https://identifiers.org/uniprot/J3QRL5> , <https://identifiers.org/uniprot/P62993> , <https://identifiers.org/uniprot/J3QLF6> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2374_r137995/DataNode/a4ea6> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/B0LPF3> , <http://purl.uniprot.org/uniprot/J3KT38> , <http://purl.uniprot.org/uniprot/J3QRL5> , <http://purl.uniprot.org/uniprot/J3QLF6> , <http://purl.uniprot.org/uniprot/P62993> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/2885> .

<http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/f12ab>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2374_r137995> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2374_r137995/Interaction/f12ab> ;
        wp:participants   <https://identifiers.org/ncbigene/3572> , <https://identifiers.org/ncbigene/7297> ;
        wp:source         <https://identifiers.org/ncbigene/7297> ;
        wp:target         <https://identifiers.org/ncbigene/3572> .

<http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/be230>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2374_r137995> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2374_r137995/Interaction/be230> ;
        wp:participants   <https://identifiers.org/ncbigene/6464> , <https://identifiers.org/ncbigene/3717> ;
        wp:source         <https://identifiers.org/ncbigene/3717> ;
        wp:target         <https://identifiers.org/ncbigene/6464> .

<http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/bb6c3>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2374_r137995> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2374_r137995/Interaction/bb6c3> ;
        wp:participants   <https://identifiers.org/ncbigene/6774> , <https://identifiers.org/ncbigene/3718> ;
        wp:source         <https://identifiers.org/ncbigene/3718> ;
        wp:target         <https://identifiers.org/ncbigene/6774> .

<http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/c40e5>
        rdf:type          wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2374_r137995> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2374_r137995/Interaction/c40e5> ;
        wp:participants   <https://identifiers.org/ncbigene/9180> .

<http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/id46666ce5>
        rdf:type          wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2374_r137995> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2374_r137995/Interaction/id46666ce5> .

<https://identifiers.org/ncbigene/6347>
        rdf:type            wp:DataNode , wp:Rna ;
        rdfs:label          "CCL2" ;
        dc:identifier       <https://identifiers.org/ncbigene/6347> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "6347" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/ab515> , <http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/dd384> , <https://identifiers.org/wikipathways/WP2374_r137995> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000108691> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/6347> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/CCL2> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/J3KRT7> , <https://identifiers.org/uniprot/P13500> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2374_r137995/DataNode/f67ea> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P13500> , <http://purl.uniprot.org/uniprot/J3KRT7> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/6347> .

<http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/b1365>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2374_r137995> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2374_r137995/Interaction/b1365> ;
        wp:participants   <https://identifiers.org/ncbigene/6777> ;
        wp:source         <https://identifiers.org/ncbigene/6777> ;
        wp:target         <https://identifiers.org/ncbigene/6777> .

<https://doi.org/10.3389%2Ffimmu.2021.769011>
        rdf:type            wp:PublicationReference ;
        dc:source           "DOI" ;
        dcterms:identifier  "10.3389/fimmu.2021.769011" ;
        cito:cites          <https://identifiers.org/wikipathways/WP2374> .

<https://identifiers.org/pubmed/18505913>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "18505913" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2374_r137995> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/18505913> .

<http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/a8894>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2374_r137995> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2374_r137995/Interaction/a8894> ;
        wp:participants   <https://identifiers.org/ncbigene/6777> , <https://identifiers.org/ncbigene/3716> ;
        wp:source         <https://identifiers.org/ncbigene/3716> ;
        wp:target         <https://identifiers.org/ncbigene/6777> .

<http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/idf7c4d4b8>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2374_r137995> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2374_r137995/Interaction/idf7c4d4b8> ;
        wp:participants   <https://identifiers.org/ncbigene/3667> , <https://identifiers.org/ncbigene/3716> ;
        wp:source         <https://identifiers.org/ncbigene/3716> ;
        wp:target         <https://identifiers.org/ncbigene/3667> .

<https://identifiers.org/ncbigene/5604>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "MAP2K1" ;
        dc:identifier       <https://identifiers.org/ncbigene/5604> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "5604" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/a90a6> , <https://identifiers.org/wikipathways/WP2374_r137995> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000169032> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/5604> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/MAP2K1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A8I5QJ96> , <https://identifiers.org/uniprot/H3BRW9> , <https://identifiers.org/uniprot/A0A8I5KYS7> , <https://identifiers.org/uniprot/B4DFY5> , <https://identifiers.org/uniprot/A0A8I5QJL9> , <https://identifiers.org/uniprot/A4QPA9> , <https://identifiers.org/uniprot/A0A8I5KXN4> , <https://identifiers.org/uniprot/A0A8I5QJP8> , <https://identifiers.org/uniprot/A0A8I5KRX5> , <https://identifiers.org/uniprot/A0A8I5KVF6> , <https://identifiers.org/uniprot/A0A8I5QJC1> , <https://identifiers.org/uniprot/A0A8I5KYB4> , <https://identifiers.org/uniprot/Q02750> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2374_r137995/DataNode/c07a2> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A8I5QJP8> , <http://purl.uniprot.org/uniprot/A0A8I5QJC1> , <http://purl.uniprot.org/uniprot/A4QPA9> , <http://purl.uniprot.org/uniprot/A0A8I5QJ96> , <http://purl.uniprot.org/uniprot/A0A8I5KVF6> , <http://purl.uniprot.org/uniprot/A0A8I5KYS7> , <http://purl.uniprot.org/uniprot/A0A8I5KXN4> , <http://purl.uniprot.org/uniprot/H3BRW9> , <http://purl.uniprot.org/uniprot/A0A8I5QJL9> , <http://purl.uniprot.org/uniprot/A0A8I5KYB4> , <http://purl.uniprot.org/uniprot/A0A8I5KRX5> , <http://purl.uniprot.org/uniprot/Q02750> , <http://purl.uniprot.org/uniprot/B4DFY5> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/5604> .

<https://identifiers.org/ncbigene/1432>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "MAPK14" ;
        dc:identifier       <https://identifiers.org/ncbigene/1432> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "1432" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/daac1> , <https://identifiers.org/wikipathways/WP2374_r137995> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000112062> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/1432> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/MAPK14> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/H7C4E2> , <https://identifiers.org/uniprot/E7EX54> , <https://identifiers.org/uniprot/Q16539> , <https://identifiers.org/uniprot/B5TY33> , <https://identifiers.org/uniprot/B4E0K5> , <https://identifiers.org/uniprot/L7RSM2> , <https://identifiers.org/uniprot/A0A024RD15> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2374_r137995/DataNode/cffe7> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/H7C4E2> , <http://purl.uniprot.org/uniprot/L7RSM2> , <http://purl.uniprot.org/uniprot/B5TY33> , <http://purl.uniprot.org/uniprot/B4E0K5> , <http://purl.uniprot.org/uniprot/A0A024RD15> , <http://purl.uniprot.org/uniprot/E7EX54> , <http://purl.uniprot.org/uniprot/Q16539> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/1432> .

<https://identifiers.org/ncbigene/1958>
        rdf:type            wp:Rna , wp:DataNode , wp:Protein ;
        rdfs:label          "EGR1" ;
        dc:identifier       <https://identifiers.org/ncbigene/1958> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "1958" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/b0247> , <https://identifiers.org/wikipathways/WP2374_r137995> , <http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/eb8ac> , <http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/f18c5> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000120738> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/1958> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/EGR1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/P18146> , <https://identifiers.org/uniprot/Q546S1> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2374_r137995/DataNode/a32d8> , <http://rdf.wikipathways.org/Pathway/WP2374_r137995/DataNode/fb447> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q546S1> , <http://purl.uniprot.org/uniprot/P18146> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/1958> .

<http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/bd195>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2374_r137995> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2374_r137995/Interaction/bd195> ;
        wp:participants   <https://identifiers.org/ncbigene/1027> , <https://identifiers.org/ncbigene/6774> ;
        wp:source         <https://identifiers.org/ncbigene/6774> ;
        wp:target         <https://identifiers.org/ncbigene/1027> .

<https://identifiers.org/ncbigene/1027>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "CDKN1B" ;
        dc:identifier       <https://identifiers.org/ncbigene/1027> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "1027" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2374_r137995> , <http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/bd195> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000111276> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/1027> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/CDKN1B> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q6I9V6> , <https://identifiers.org/uniprot/E7ES52> , <https://identifiers.org/uniprot/H7C2T1> , <https://identifiers.org/uniprot/P46527> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2374_r137995/DataNode/aeb0d> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/E7ES52> , <http://purl.uniprot.org/uniprot/P46527> , <http://purl.uniprot.org/uniprot/H7C2T1> , <http://purl.uniprot.org/uniprot/Q6I9V6> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/1027> .

<http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/add52>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2374_r137995> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2374_r137995/Interaction/add52> ;
        wp:participants   <https://identifiers.org/ncbigene/6464> , <https://identifiers.org/ncbigene/2885> ;
        wp:source         <https://identifiers.org/ncbigene/2885> ;
        wp:target         <https://identifiers.org/ncbigene/6464> .

<https://identifiers.org/ncbigene/2475>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "MTOR" ;
        dc:identifier       <https://identifiers.org/ncbigene/2475> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "2475" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2374_r137995> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000198793> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/2475> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/MTOR> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A8V8TR74> , <https://identifiers.org/uniprot/A0A8V8TQM6> , <https://identifiers.org/uniprot/A0A8V8TRG9> , <https://identifiers.org/uniprot/A0A8V8TQN3> , <https://identifiers.org/uniprot/A0A8V8TQ52> , <https://identifiers.org/uniprot/P42345> , <https://identifiers.org/uniprot/A0A8V8TQP2> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2374_r137995/DataNode/a57b4> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A8V8TQM6> , <http://purl.uniprot.org/uniprot/A0A8V8TQ52> , <http://purl.uniprot.org/uniprot/A0A8V8TQN3> , <http://purl.uniprot.org/uniprot/A0A8V8TR74> , <http://purl.uniprot.org/uniprot/A0A8V8TRG9> , <http://purl.uniprot.org/uniprot/A0A8V8TQP2> , <http://purl.uniprot.org/uniprot/P42345> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/2475> .

<http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/id2d32c46f>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2374_r137995> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2374_r137995/Interaction/id2d32c46f> ;
        wp:participants   <https://identifiers.org/ncbigene/6774> , <https://identifiers.org/ncbigene/3716> ;
        wp:source         <https://identifiers.org/ncbigene/3716> ;
        wp:target         <https://identifiers.org/ncbigene/6774> .

<http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/cb214>
        rdf:type          wp:Inhibition , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2374_r137995> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2374_r137995/Interaction/cb214> ;
        wp:participants   <https://identifiers.org/ncbigene/3716> , <https://identifiers.org/ncbigene/9021> ;
        wp:source         <https://identifiers.org/ncbigene/9021> ;
        wp:target         <https://identifiers.org/ncbigene/3716> .

<https://identifiers.org/wikipathways/WP2374_r137995>
        rdf:type                wp:Pathway , skos:Collection ;
        dc:identifier           <https://identifiers.org/wikipathways/WP2374> ;
        dc:source               "WikiPathways" ;
        dc:title                "Oncostatin M signaling"@en ;
        dcterms:description     "Oncostatin M (OSM) is a member of the multifunctional cytokine interleukin 6 (IL6) - type cytokine family. It is mainly produced in activated T lymphocytes, macrophages, monocytes, neutrophils, and microglial cells. OSM signaling is initiated by the interaction of the cytokine to either: the type I LIFR-gp130 receptor complex, or to the type II OSMR-gp130 receptor (O’Hara et al). The major downstream signaling pathways that are activated in OSM signaling are JAK/STAT, Ras/Raf/MAPK and PI3K pathways (Halfter, Halfter, Stross, Brantley). As the receptors lack intrinsic tyrosine kinase activity, associated JAKs (JAK1, JAK2, JAK3 and TYK2) phosphorylate OSM receptor complex and STATs (STAT1, STAT3, STAT5A, STAT5B, STAT6) (O’Hara, Fritz, Migita, Hintzen). Phosphorylated STATs form homodimeric complexes (STAT1, STAT3, STAT5B) or heterodimeric complex (STAT1-STAT3) and translocate to the nucleus. Once inside nucleus STAT proteins bind to regulatory elements in the promoter of OSM-responsive genes and regulate the gene expression (O’Hara, Halfter, Halfter, Hintzen). Alternatively, OSM induced phosphorylation of PTPN11, GRB2, SHC1, Ras/Raf molecules can bring about the activation of ERK1/2 signaling module (O’Hara). Oncostatin M -through ERK1/2 signaling module induces the phosphorylation of CEBPB, both CEBPB and EGR1 stimulates the transcription of genes involved in lipid metabolism (Zhang). Although OSM also causes induced phosphorylation in MAPK family members (MAPK8/9/14) the functional importance of this is at present not well understood (O’Hara, Li). OSM mediated signaling cascade is negatively regulated by JAK1 inhibition by SOCS3 and STAT3 inhibition by PIAS3 (Stross, Brantley, Chung). OSM also induces the activation of caspase family members (CASP3, CASP7, CASP9) through the JAK2 module and regulates apoptosis (Auernhammer, Tiffen, Chipoy). In osteosarcoma cells, OSM mediates apoptosis through a less understood STAT5B signaling module (Chipoy). " ;
        dcterms:identifier      "WP2374" ;
        dcterms:references      <https://identifiers.org/pubmed/21548952> , <https://identifiers.org/pubmed/12911774> , <https://identifiers.org/pubmed/11207308> , <https://identifiers.org/pubmed/17471233> , <https://identifiers.org/pubmed/16547273> , <https://identifiers.org/pubmed/10356359> , <https://identifiers.org/pubmed/18927239> , <https://identifiers.org/pubmed/16459330> , <https://identifiers.org/pubmed/18505913> , <https://identifiers.org/pubmed/9388184> , <https://identifiers.org/pubmed/12947119> , <https://identifiers.org/pubmed/15012602> , <https://identifiers.org/pubmed/11038252> , <https://identifiers.org/pubmed/18430728> ;
        cito:cites              <https://identifiers.org/pubmed/16459330> , <https://identifiers.org/pubmed/16547273> , <https://identifiers.org/pubmed/11038252> , <https://identifiers.org/pubmed/9388184> , <https://identifiers.org/pubmed/18430728> , <https://identifiers.org/pubmed/17471233> , <https://identifiers.org/pubmed/11207308> , <https://identifiers.org/pubmed/21548952> , <https://identifiers.org/pubmed/15012602> , <https://identifiers.org/pubmed/12947119> , <https://identifiers.org/pubmed/18505913> , <https://identifiers.org/pubmed/10356359> , <https://identifiers.org/pubmed/12911774> , <https://identifiers.org/pubmed/18927239> ;
        wp:cellTypeOntologyTag  obo:CL_0002097 , obo:CL_0002539 , obo:CL_0002326 , obo:CL_0000127 , obo:CL_0000062 , obo:CL_0002327 ;
        wp:diseaseOntologyTag   obo:DOID_3347 , obo:DOID_3905 ;
        wp:isAbout              <http://rdf.wikipathways.org/Pathway/WP2374_r137995> ;
        wp:ontologyTag          obo:CL_0002327 , obo:CL_0000127 , obo:DOID_3905 , obo:CL_0002326 , obo:CL_0002539 , obo:DOID_3347 , obo:CL_0000062 , wp:Curation:AnalysisCollection , obo:CL_0002097 , obo:PW_0000905 ;
        wp:organism             obo:NCBITaxon_9606 ;
        wp:organismName         "Homo sapiens" ;
        wp:pathwayOntologyTag   obo:PW_0000905 ;
        foaf:img                <https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=svg&pwTitle=Pathway:WP2374&oldid=137995> , <https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=png&pwTitle=Pathway:WP2374&oldid=137995> ;
        foaf:page               <http://www.wikipathways.org/instance/WP2374_r137995> .

<https://identifiers.org/ensembl/ENSG00000100644>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "HIF1A" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000100644> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000100644" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2374_r137995> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000100644> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/3091> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/HIF1A> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q16665> , <https://identifiers.org/uniprot/A8MYV6> , <https://identifiers.org/uniprot/D0VY79> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q20970095> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2374_r137995/DataNode/bb721> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q16665> , <http://purl.uniprot.org/uniprot/D0VY79> , <http://purl.uniprot.org/uniprot/A8MYV6> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000100644> .

<https://identifiers.org/ncbigene/3718>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "JAK3" ;
        dc:identifier       <https://identifiers.org/ncbigene/3718> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "3718" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/fb11b> , <https://identifiers.org/wikipathways/WP2374_r137995> , <http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/d723b> , <http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/bb6c3> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000105639> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/3718> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/JAK3> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/P52333> , <https://identifiers.org/uniprot/A0A0S2Z4R7> , <https://identifiers.org/uniprot/A0A024R7M7> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2374_r137995/DataNode/a5d1b> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P52333> , <http://purl.uniprot.org/uniprot/A0A024R7M7> , <http://purl.uniprot.org/uniprot/A0A0S2Z4R7> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/3718> .

<http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/d91d1>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2374_r137995> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2374_r137995/Interaction/d91d1> ;
        wp:participants   <https://identifiers.org/ncbigene/3572> , <https://identifiers.org/ncbigene/3716> ;
        wp:source         <https://identifiers.org/ncbigene/3716> ;
        wp:target         <https://identifiers.org/ncbigene/3572> .

<http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/b0a67>
        rdf:type          wp:TranscriptionTranslation , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2374_r137995> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2374_r137995/Interaction/b0a67> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000112715> , <https://identifiers.org/ncbigene/5594> ;
        wp:source         <https://identifiers.org/ncbigene/5594> ;
        wp:target         <https://identifiers.org/ensembl/ENSG00000112715> .

<https://identifiers.org/ncbigene/5583>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "PRKCH" ;
        dc:identifier       <https://identifiers.org/ncbigene/5583> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "5583" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2374_r137995> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000027075> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/5583> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/PRKCH> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/P24723> , <https://identifiers.org/uniprot/G3V4Q9> , <https://identifiers.org/uniprot/G3V3E7> , <https://identifiers.org/uniprot/G3V4X4> , <https://identifiers.org/uniprot/G3V304> , <https://identifiers.org/uniprot/G3V4Q6> , <https://identifiers.org/uniprot/G3V5U5> , <https://identifiers.org/uniprot/G3V4H0> , <https://identifiers.org/uniprot/G3V5F8> , <https://identifiers.org/uniprot/G3V520> , <https://identifiers.org/uniprot/G3V4G6> , <https://identifiers.org/uniprot/G3V5Y6> , <https://identifiers.org/uniprot/G3V4L3> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2374_r137995/DataNode/f2f61> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/G3V4Q9> , <http://purl.uniprot.org/uniprot/G3V520> , <http://purl.uniprot.org/uniprot/G3V5U5> , <http://purl.uniprot.org/uniprot/G3V5F8> , <http://purl.uniprot.org/uniprot/G3V304> , <http://purl.uniprot.org/uniprot/G3V4H0> , <http://purl.uniprot.org/uniprot/G3V5Y6> , <http://purl.uniprot.org/uniprot/G3V4G6> , <http://purl.uniprot.org/uniprot/G3V4L3> , <http://purl.uniprot.org/uniprot/G3V4X4> , <http://purl.uniprot.org/uniprot/G3V3E7> , <http://purl.uniprot.org/uniprot/P24723> , <http://purl.uniprot.org/uniprot/G3V4Q6> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/5583> .

<http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/id64fa041c>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2374_r137995> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2374_r137995/Interaction/id64fa041c> ;
        wp:participants   <https://identifiers.org/ncbigene/5970> , <https://identifiers.org/ncbigene/4792> ;
        wp:source         <https://identifiers.org/ncbigene/4792> ;
        wp:target         <https://identifiers.org/ncbigene/5970> .

<http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/c97c2>
        rdf:type          wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2374_r137995> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2374_r137995/Interaction/c97c2> ;
        wp:participants   <https://identifiers.org/ncbigene/5008> .

<http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/c1912>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2374_r137995> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2374_r137995/Interaction/c1912> ;
        wp:participants   <https://identifiers.org/ncbigene/2353> , <https://identifiers.org/ncbigene/6774> ;
        wp:source         <https://identifiers.org/ncbigene/6774> ;
        wp:target         <https://identifiers.org/ncbigene/2353> .

<https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=svg&pwTitle=Pathway:WP2374&oldid=137995>
        rdf:type        foaf:Image ;
        dcterms:format  "image/svg+xml" .

<https://identifiers.org/pmc/PMC3660694>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed Central" ;
        dcterms:identifier  "PMC3660694" ;
        cito:cites          <https://identifiers.org/wikipathways/WP2374> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/PMC3660694> .

<http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/fd9c2>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2374_r137995> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2374_r137995/Interaction/fd9c2> ;
        wp:participants   <https://identifiers.org/ncbigene/4790> ;
        wp:source         <https://identifiers.org/ncbigene/4790> ;
        wp:target         <https://identifiers.org/ncbigene/4790> .

<http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/b0d38>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2374_r137995> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2374_r137995/Interaction/b0d38> ;
        wp:participants   <https://identifiers.org/ncbigene/6774> , <https://identifiers.org/ncbigene/6772> ;
        wp:source         <https://identifiers.org/ncbigene/6772> ;
        wp:target         <https://identifiers.org/ncbigene/6774> .

<https://identifiers.org/ncbigene/10401>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "PIAS3" ;
        dc:identifier       <https://identifiers.org/ncbigene/10401> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "10401" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2374_r137995> , <http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/ide9ae73cb> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000131788> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/10401> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/PIAS3> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/E7ESB4> , <https://identifiers.org/uniprot/U3KQV1> , <https://identifiers.org/uniprot/E9PHH8> , <https://identifiers.org/uniprot/Q9Y6X2> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2374_r137995/DataNode/cc27e> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/E7ESB4> , <http://purl.uniprot.org/uniprot/U3KQV1> , <http://purl.uniprot.org/uniprot/E9PHH8> , <http://purl.uniprot.org/uniprot/Q9Y6X2> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/10401> .

<http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/d2dd5>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2374_r137995> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2374_r137995/Interaction/d2dd5> ;
        wp:participants   <https://identifiers.org/ncbigene/5894> , <https://identifiers.org/ncbigene/3716> ;
        wp:source         <https://identifiers.org/ncbigene/3716> ;
        wp:target         <https://identifiers.org/ncbigene/5894> .

<https://identifiers.org/ncbigene/3726>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "JUNB" ;
        dc:identifier       <https://identifiers.org/ncbigene/3726> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "3726" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2374_r137995> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000171223> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/3726> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/JUNB> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q5U079> , <https://identifiers.org/uniprot/P17275> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2374_r137995/DataNode/d9f0e> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q5U079> , <http://purl.uniprot.org/uniprot/P17275> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/3726> .

<https://identifiers.org/ncbigene/4314>
        rdf:type            wp:DataNode , wp:Rna ;
        rdfs:label          "MMP3" ;
        dc:identifier       <https://identifiers.org/ncbigene/4314> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "4314" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2374_r137995> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000149968> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/4314> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/MMP3> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/H7C139> , <https://identifiers.org/uniprot/P08254> , <https://identifiers.org/uniprot/E9PKX2> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2374_r137995/DataNode/b414f> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P08254> , <http://purl.uniprot.org/uniprot/H7C139> , <http://purl.uniprot.org/uniprot/E9PKX2> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/4314> .

<https://identifiers.org/ncbigene/4790>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "NFKB1" ;
        dc:identifier       <https://identifiers.org/ncbigene/4790> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "4790" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/fd9c2> , <https://identifiers.org/wikipathways/WP2374_r137995> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000109320> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/4790> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/NFKB1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/D6RH30> , <https://identifiers.org/uniprot/A0A8V8TLB2> , <https://identifiers.org/uniprot/D6RC45> , <https://identifiers.org/uniprot/P19838> , <https://identifiers.org/uniprot/A0A494C1E9> , <https://identifiers.org/uniprot/A0A494C157> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2374_r137995/DataNode/c33d2> , <http://rdf.wikipathways.org/Pathway/WP2374_r137995/DataNode/a2d29> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/D6RH30> , <http://purl.uniprot.org/uniprot/P19838> , <http://purl.uniprot.org/uniprot/A0A8V8TLB2> , <http://purl.uniprot.org/uniprot/A0A494C157> , <http://purl.uniprot.org/uniprot/D6RC45> , <http://purl.uniprot.org/uniprot/A0A494C1E9> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/4790> .

<http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/ea7b2>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2374_r137995> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2374_r137995/Interaction/ea7b2> ;
        wp:participants   <https://identifiers.org/ncbigene/6777> , <https://identifiers.org/ncbigene/9180> ;
        wp:source         <https://identifiers.org/ncbigene/9180> ;
        wp:target         <https://identifiers.org/ncbigene/6777> .

<https://identifiers.org/ncbigene/4322>
        rdf:type            wp:Rna , wp:DataNode ;
        rdfs:label          "MMP13" ;
        dc:identifier       <https://identifiers.org/ncbigene/4322> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "4322" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2374_r137995> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000137745> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/4322> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/MMP13> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/P45452> , <https://identifiers.org/uniprot/G5E971> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2374_r137995/DataNode/b3a56> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P45452> , <http://purl.uniprot.org/uniprot/G5E971> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/4322> .

<https://identifiers.org/pubmed/12947119>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "12947119" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2374_r137995> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/12947119> .

<https://identifiers.org/ncbigene/5599>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "MAPK8" ;
        dc:identifier       <https://identifiers.org/ncbigene/5599> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "5599" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2374_r137995> , <http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/ed0da> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000107643> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/5599> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/MAPK8> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A3B3IRW7> , <https://identifiers.org/uniprot/C9J762> , <https://identifiers.org/uniprot/A1L4K2> , <https://identifiers.org/uniprot/C9JWQ4> , <https://identifiers.org/uniprot/P45983> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2374_r137995/DataNode/af899> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/C9JWQ4> , <http://purl.uniprot.org/uniprot/C9J762> , <http://purl.uniprot.org/uniprot/A0A3B3IRW7> , <http://purl.uniprot.org/uniprot/P45983> , <http://purl.uniprot.org/uniprot/A1L4K2> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/5599> .

<https://identifiers.org/ncbigene/5578>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "PRKCA" ;
        dc:identifier       <https://identifiers.org/ncbigene/5578> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "5578" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2374_r137995> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000154229> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/5578> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/PRKCA> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/L7RSM7> , <https://identifiers.org/uniprot/J3KN97> , <https://identifiers.org/uniprot/P17252> , <https://identifiers.org/uniprot/J3KRN5> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2374_r137995/DataNode/a9f88> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P17252> , <http://purl.uniprot.org/uniprot/J3KRN5> , <http://purl.uniprot.org/uniprot/J3KN97> , <http://purl.uniprot.org/uniprot/L7RSM7> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/5578> .

<https://identifiers.org/ncbigene/1051>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "CEBPB" ;
        dc:identifier       <https://identifiers.org/ncbigene/1051> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "1051" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/b0247> , <https://identifiers.org/wikipathways/WP2374_r137995> , <http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/f7ad3> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000172216> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/1051> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/CEBPB> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/P17676> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2374_r137995/DataNode/ea814> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P17676> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/1051> .

<http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/dd384>
        rdf:type          wp:Interaction , wp:DirectedInteraction , wp:TranscriptionTranslation ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2374_r137995> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2374_r137995/Interaction/dd384> , <http://rdf.wikipathways.org/Pathway/WP2374_r137995/Interaction/fa2f7> ;
        wp:participants   <https://identifiers.org/ncbigene/6347> , <https://identifiers.org/ncbigene/6772> ;
        wp:source         <https://identifiers.org/ncbigene/6772> ;
        wp:target         <https://identifiers.org/ncbigene/6347> .

<https://identifiers.org/ncbigene/1385>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "CREB1" ;
        dc:identifier       <https://identifiers.org/ncbigene/1385> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "1385" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2374_r137995> , <http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/b0531> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000118260> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/1385> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/CREB1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/P16220> , <https://identifiers.org/uniprot/C9J4L5> , <https://identifiers.org/uniprot/H7C3I0> , <https://identifiers.org/uniprot/C9JCI4> , <https://identifiers.org/uniprot/C9J276> , <https://identifiers.org/uniprot/H7C1R5> , <https://identifiers.org/uniprot/E7EWP8> , <https://identifiers.org/uniprot/Q53X93> , <https://identifiers.org/uniprot/Q5U0J5> , <https://identifiers.org/uniprot/C9JBT4> , <https://identifiers.org/uniprot/C9J896> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2374_r137995/DataNode/e6d5b> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/C9JBT4> , <http://purl.uniprot.org/uniprot/H7C1R5> , <http://purl.uniprot.org/uniprot/C9J4L5> , <http://purl.uniprot.org/uniprot/C9JCI4> , <http://purl.uniprot.org/uniprot/E7EWP8> , <http://purl.uniprot.org/uniprot/P16220> , <http://purl.uniprot.org/uniprot/C9J276> , <http://purl.uniprot.org/uniprot/Q53X93> , <http://purl.uniprot.org/uniprot/C9J896> , <http://purl.uniprot.org/uniprot/H7C3I0> , <http://purl.uniprot.org/uniprot/Q5U0J5> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/1385> .

<https://identifiers.org/ncbigene/207>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "AKT1" ;
        dc:identifier       <https://identifiers.org/ncbigene/207> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "207" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/cf4c8> , <http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/ccceb> , <http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/d90ba> , <http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/cd7ab> , <https://identifiers.org/wikipathways/WP2374_r137995> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000142208> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/207> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/AKT1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/P31749> , <https://identifiers.org/uniprot/A0A804HJM6> , <https://identifiers.org/uniprot/B0LPE5> , <https://identifiers.org/uniprot/G3V2I6> , <https://identifiers.org/uniprot/A0A087WY56> , <https://identifiers.org/uniprot/G3V3X1> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2374_r137995/DataNode/a2298> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/G3V2I6> , <http://purl.uniprot.org/uniprot/B0LPE5> , <http://purl.uniprot.org/uniprot/A0A804HJM6> , <http://purl.uniprot.org/uniprot/A0A087WY56> , <http://purl.uniprot.org/uniprot/P31749> , <http://purl.uniprot.org/uniprot/G3V3X1> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/207> .

<http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/ab515>
        rdf:type          wp:TranscriptionTranslation , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2374_r137995> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2374_r137995/Interaction/ab515> ;
        wp:participants   <https://identifiers.org/ncbigene/6347> , <https://identifiers.org/ncbigene/2353> ;
        wp:source         <https://identifiers.org/ncbigene/2353> ;
        wp:target         <https://identifiers.org/ncbigene/6347> .

<https://identifiers.org/ncbigene/5970>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "RELA" ;
        dc:identifier       <https://identifiers.org/ncbigene/5970> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "5970" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/f8a05> , <http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/b212e> , <http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/c2280> , <https://identifiers.org/wikipathways/WP2374_r137995> , <http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/cf4c8> , <http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/id64fa041c> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000173039> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/5970> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/RELA> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A087X0W8> , <https://identifiers.org/uniprot/E9PSE4> , <https://identifiers.org/uniprot/E9PQS6> , <https://identifiers.org/uniprot/E9PKH5> , <https://identifiers.org/uniprot/E9PMD5> , <https://identifiers.org/uniprot/H0YCB4> , <https://identifiers.org/uniprot/E9PI38> , <https://identifiers.org/uniprot/E9PKV4> , <https://identifiers.org/uniprot/Q2TAM5> , <https://identifiers.org/uniprot/E9PM47> , <https://identifiers.org/uniprot/Q04206> , <https://identifiers.org/uniprot/E9PJR1> , <https://identifiers.org/uniprot/E9PNV4> , <https://identifiers.org/uniprot/E9PNK5> , <https://identifiers.org/uniprot/E9PRX2> , <https://identifiers.org/uniprot/E9PJZ9> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2374_r137995/DataNode/bb53d> , <http://rdf.wikipathways.org/Pathway/WP2374_r137995/DataNode/d52b4> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/E9PJZ9> , <http://purl.uniprot.org/uniprot/E9PJR1> , <http://purl.uniprot.org/uniprot/E9PKH5> , <http://purl.uniprot.org/uniprot/H0YCB4> , <http://purl.uniprot.org/uniprot/E9PNK5> , <http://purl.uniprot.org/uniprot/Q04206> , <http://purl.uniprot.org/uniprot/E9PMD5> , <http://purl.uniprot.org/uniprot/E9PM47> , <http://purl.uniprot.org/uniprot/E9PSE4> , <http://purl.uniprot.org/uniprot/A0A087X0W8> , <http://purl.uniprot.org/uniprot/Q2TAM5> , <http://purl.uniprot.org/uniprot/E9PQS6> , <http://purl.uniprot.org/uniprot/E9PKV4> , <http://purl.uniprot.org/uniprot/E9PI38> , <http://purl.uniprot.org/uniprot/E9PRX2> , <http://purl.uniprot.org/uniprot/E9PNV4> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/5970> .

<https://identifiers.org/pubmed/15012602>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "15012602" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2374_r137995> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/15012602> .

<https://identifiers.org/ncbigene/1017>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "CDK2" ;
        dc:identifier       <https://identifiers.org/ncbigene/1017> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "1017" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2374_r137995> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000123374> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/1017> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/CDK2> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A024RB10> , <https://identifiers.org/uniprot/G3V317> , <https://identifiers.org/uniprot/P24941> , <https://identifiers.org/uniprot/E7ESI2> , <https://identifiers.org/uniprot/G3V5T9> , <https://identifiers.org/uniprot/A0A024RB77> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2374_r137995/DataNode/a22a5> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/G3V317> , <http://purl.uniprot.org/uniprot/P24941> , <http://purl.uniprot.org/uniprot/G3V5T9> , <http://purl.uniprot.org/uniprot/E7ESI2> , <http://purl.uniprot.org/uniprot/A0A024RB10> , <http://purl.uniprot.org/uniprot/A0A024RB77> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/1017> .

<http://rdf.wikipathways.org/Pathway/WP2374_r137995/WP/Interaction/ccceb>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2374_r137995> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2374_r137995/Interaction/ccceb> ;
        wp:participants   <https://identifiers.org/ncbigene/6774> , <https://identifiers.org/ncbigene/207> ;
        wp:source         <https://identifiers.org/ncbigene/207> ;
        wp:target         <https://identifiers.org/ncbigene/6774> .
