@prefix biopax:  <http://www.biopax.org/release/biopax-level3.owl#> .
@prefix cito:    <http://purl.org/spar/cito/> .
@prefix dc:      <http://purl.org/dc/elements/1.1/> .
@prefix dcterms: <http://purl.org/dc/terms/> .
@prefix foaf:    <http://xmlns.com/foaf/0.1/> .
@prefix freq:    <http://purl.org/cld/freq/> .
@prefix gpml:    <http://vocabularies.wikipathways.org/gpml#> .
@prefix obo:     <http://purl.obolibrary.org/obo/> .
@prefix owl:     <http://www.w3.org/2002/07/owl#> .
@prefix pav:     <http://purl.org/pav/> .
@prefix prov:    <http://www.w3.org/ns/prov#> .
@prefix rdf:     <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix rdfs:    <http://www.w3.org/2000/01/rdf-schema#> .
@prefix skos:    <http://www.w3.org/2004/02/skos/core#> .
@prefix void:    <http://rdfs.org/ns/void#> .
@prefix wp:      <http://vocabularies.wikipathways.org/wp#> .
@prefix wprdf:   <http://rdf.wikipathways.org/> .
@prefix xsd:     <http://www.w3.org/2001/XMLSchema#> .

obo:NCBITaxon_9606  obo:NCIT_C179773  "9606" .

<https://identifiers.org/wikipathways/WP4400>
        pav:hasVersion  <https://identifiers.org/wikipathways/WP4400_r141653> .

<https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=png&pwTitle=Pathway:WP4400&oldid=141653>
        rdf:type        foaf:Image ;
        dcterms:format  "image/png" .

<https://identifiers.org/ensembl/ENSG00000199107>
        rdf:type            wp:Rna , wp:DataNode ;
        rdfs:label          "MIR409" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000199107> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000199107" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4400_r141653> , <http://rdf.wikipathways.org/Pathway/WP4400_r141653/WP/Interaction/id9d7db212> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000199107> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/574413> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/MIR409> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18059157> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4400_r141653/DataNode/d26ef> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000199107> .

<http://rdf.wikipathways.org/Pathway/WP4400_r141653/WP/Interaction/id9d7db212>
        rdf:type          wp:Inhibition , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4400_r141653> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4400_r141653/Interaction/id9d7db212> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000170323> , <https://identifiers.org/ensembl/ENSG00000199107> ;
        wp:source         <https://identifiers.org/ensembl/ENSG00000199107> ;
        wp:target         <https://identifiers.org/ensembl/ENSG00000170323> .

<https://identifiers.org/wikipathways/WP4400_r141653>
        rdf:type                wp:Pathway , skos:Collection ;
        dc:identifier           <https://identifiers.org/wikipathways/WP4400> ;
        dc:source               "WikiPathways" ;
        dc:title                "FABP4 in ovarian cancer"@en ;
        dcterms:description     "Regulation of FABP4 in ovarian cancer. FABP4 (fatty acid binding protein) can substantially increase metastatic potential of ovarian cancer cells, and leads to more aggressive disease. Mir-409-3p negatively regulates FABP4 in ovarian cancer cells, and mir-409-3p is decreased in hypoxic conditions. Pink arrows indicates potential therapuetic therapeutic stratgeies; in Gharpure et al, DOPC nanoliposomes containing either miR-409-3p mimic or FABP4 siRNA was shown to inhibit tumor progression. \nDescription was adapted from Gharpure et al. " ;
        dcterms:identifier      "WP4400" ;
        dcterms:references      <https://identifiers.org/pubmed/30050129> ;
        cito:cites              <https://identifiers.org/pubmed/30050129> ;
        wp:cellTypeOntologyTag  obo:CL_0001063 ;
        wp:diseaseOntologyTag   obo:DOID_2394 ;
        wp:isAbout              <http://rdf.wikipathways.org/Pathway/WP4400_r141653> ;
        wp:ontologyTag          obo:PW_0000808 , wp:Curation:CPTAC , wp:Curation:AnalysisCollection , obo:CL_0001063 , obo:DOID_2394 , wp:Curation:ExRNA , obo:PW_0000605 ;
        wp:organism             obo:NCBITaxon_9606 ;
        wp:organismName         "Homo sapiens" ;
        wp:pathwayOntologyTag   obo:PW_0000605 , obo:PW_0000808 ;
        foaf:img                <https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=svg&pwTitle=Pathway:WP4400&oldid=141653> , <https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=png&pwTitle=Pathway:WP4400&oldid=141653> ;
        foaf:page               <http://www.wikipathways.org/instance/WP4400_r141653> .

<https://identifiers.org/pubmed/30050129>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "30050129" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4400_r141653> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/30050129> .

<https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=svg&pwTitle=Pathway:WP4400&oldid=141653>
        rdf:type        foaf:Image ;
        dcterms:format  "image/svg+xml" .

<https://identifiers.org/ensembl/ENSG00000170323>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "FABP4" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000170323> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000170323" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4400_r141653/WP/Interaction/id9d7db212> , <https://identifiers.org/wikipathways/WP4400_r141653> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000170323> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/2167> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/FABP4> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/E5RIR0> , <https://identifiers.org/uniprot/E7DVW4> , <https://identifiers.org/uniprot/P15090> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q14889263> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4400_r141653/DataNode/cce25> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/E5RIR0> , <http://purl.uniprot.org/uniprot/P15090> , <http://purl.uniprot.org/uniprot/E7DVW4> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000170323> .
