@prefix biopax:  <http://www.biopax.org/release/biopax-level3.owl#> .
@prefix cito:    <http://purl.org/spar/cito/> .
@prefix dc:      <http://purl.org/dc/elements/1.1/> .
@prefix dcterms: <http://purl.org/dc/terms/> .
@prefix foaf:    <http://xmlns.com/foaf/0.1/> .
@prefix freq:    <http://purl.org/cld/freq/> .
@prefix gpml:    <http://vocabularies.wikipathways.org/gpml#> .
@prefix obo:     <http://purl.obolibrary.org/obo/> .
@prefix owl:     <http://www.w3.org/2002/07/owl#> .
@prefix pav:     <http://purl.org/pav/> .
@prefix prov:    <http://www.w3.org/ns/prov#> .
@prefix rdf:     <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix rdfs:    <http://www.w3.org/2000/01/rdf-schema#> .
@prefix skos:    <http://www.w3.org/2004/02/skos/core#> .
@prefix void:    <http://rdfs.org/ns/void#> .
@prefix wp:      <http://vocabularies.wikipathways.org/wp#> .
@prefix wprdf:   <http://rdf.wikipathways.org/> .
@prefix xsd:     <http://www.w3.org/2001/XMLSchema#> .

<https://identifiers.org/pmc/PMC12309373>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed Central" ;
        dcterms:identifier  "PMC12309373" ;
        cito:cites          <https://identifiers.org/wikipathways/WP1355> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/PMC12309373> .

<https://identifiers.org/ncbigene/541347>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "zgc:110308" ;
        dc:identifier       <https://identifiers.org/ncbigene/541347> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "541347" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP1355_r116584> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSDARG00000012932> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/541347> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/E9QCP2> , <https://identifiers.org/uniprot/F1RDD5> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP1355_r116584/DataNode/d10> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/E9QCP2> , <http://purl.uniprot.org/uniprot/F1RDD5> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/541347> .

<https://identifiers.org/ncbigene/560667>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "LOC560667" ;
        dc:identifier       <https://identifiers.org/ncbigene/560667> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "560667" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP1355_r116584> ;
        dcterms:references  <https://identifiers.org/pubmed/17389618> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSDARG00000045398> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/560667> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/F8W4Q3> , <https://identifiers.org/uniprot/F1RE28> , <https://identifiers.org/uniprot/A0A2R8QQ95> , <https://identifiers.org/uniprot/A0A0R4IWY4> , <https://identifiers.org/uniprot/F8W423> , <https://identifiers.org/uniprot/A0A0R4IZR6> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP1355_r116584/DataNode/ccb> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A0R4IWY4> , <http://purl.uniprot.org/uniprot/F1RE28> , <http://purl.uniprot.org/uniprot/F8W423> , <http://purl.uniprot.org/uniprot/F8W4Q3> , <http://purl.uniprot.org/uniprot/A0A0R4IZR6> , <http://purl.uniprot.org/uniprot/A0A2R8QQ95> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/560667> .

<https://identifiers.org/ncbigene/100003075>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "LOC100003075" ;
        dc:identifier       <https://identifiers.org/ncbigene/100003075> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "100003075" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP1355_r116584/WP/Interaction/fe74f> , <https://identifiers.org/wikipathways/WP1355_r116584> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/100003075> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP1355_r116584/DataNode/a74> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/100003075> .

<https://identifiers.org/cas/107-43-7>
        rdf:type            wp:Metabolite , wp:DataNode ;
        rdfs:label          "Betaine" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/KWIUHFFTVRNATP-UHFFFAOYSA-N> ;
        dc:identifier       <https://identifiers.org/cas/107-43-7> ;
        dc:source           "CAS" ;
        dcterms:identifier  "107-43-7" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP1355_r116584> , <http://rdf.wikipathways.org/Pathway/WP1355_r116584/WP/Interaction/c5efd> ;
        dcterms:references  <https://identifiers.org/pubmed/17389618> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:17750> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/242> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/KWIUHFFTVRNATP-UHFFFAOYSA-N> ;
        wp:bdbKeggCompound  <https://identifiers.org/kegg.compound/C00719> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID247> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q10860583> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP1355_r116584/DataNode/aeb> ;
        foaf:page           <https://commonchemistry.cas.org/detail?cas_rn=107-43-7> .

<http://rdf.wikipathways.org/Pathway/WP1355_r116584/WP/Interaction/c422d>
        rdf:type          wp:Interaction , wp:DirectedInteraction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP1355_r116584> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP1355_r116584/Interaction/f2928> , <http://rdf.wikipathways.org/Pathway/WP1355_r116584/Interaction/c422d> ;
        wp:participants   <https://identifiers.org/cas/59-30-3> , <https://identifiers.org/cas/4033-27-6> , <https://identifiers.org/ncbigene/81882> ;
        wp:source         <https://identifiers.org/cas/59-30-3> , <https://identifiers.org/ncbigene/81882> ;
        wp:target         <https://identifiers.org/cas/4033-27-6> .

<https://identifiers.org/cas/25513-46-6>
        rdf:type            wp:DataNode , wp:Metabolite ;
        rdfs:label          "Polyglutamate" ;
        dc:identifier       <https://identifiers.org/cas/25513-46-6> ;
        dc:source           "CAS" ;
        dcterms:identifier  "25513-46-6" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP1355_r116584/WP/Interaction/a846a> , <https://identifiers.org/wikipathways/WP1355_r116584> ;
        dcterms:references  <https://identifiers.org/pubmed/17389618> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:53374> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q26995368> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP1355_r116584/DataNode/fed> ;
        foaf:page           <https://commonchemistry.cas.org/detail?cas_rn=25513-46-6> .

<https://identifiers.org/ncbigene/81540>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "tyms" ;
        dc:identifier       <https://identifiers.org/ncbigene/81540> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "81540" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP1355_r116584/WP/Interaction/f04fe> , <https://identifiers.org/wikipathways/WP1355_r116584> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSDARG00000042894> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/81540> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q6P045> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP1355_r116584/DataNode/df4> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q6P045> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/81540> .

<https://identifiers.org/cas/59-30-3>
        rdf:type            wp:DataNode , wp:Metabolite ;
        rdfs:label          "Monoglutamate" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/OVBPIULPVIDEAO-LBPRGKRZSA-N> ;
        dc:identifier       <https://identifiers.org/cas/59-30-3> ;
        dc:source           "CAS" ;
        dcterms:identifier  "59-30-3" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP1355_r116584/WP/Interaction/f808b> , <http://rdf.wikipathways.org/Pathway/WP1355_r116584/WP/Interaction/c422d> , <http://rdf.wikipathways.org/Pathway/WP1355_r116584/WP/Interaction/a846a> , <https://identifiers.org/wikipathways/WP1355_r116584> ;
        dcterms:references  <https://identifiers.org/pubmed/17389618> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:27470> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/5815> ;
        wp:bdbHmdb          <https://identifiers.org/hmdb/HMDB0000121> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/OVBPIULPVIDEAO-LBPRGKRZSA-N> ;
        wp:bdbKeggCompound  <https://identifiers.org/kegg.compound/C00504> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID135398658> , <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID6037> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q127060> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP1355_r116584/DataNode/ccf> ;
        foaf:page           <https://commonchemistry.cas.org/detail?cas_rn=59-30-3> .

<https://identifiers.org/cas/29908-03-0>
        rdf:type            wp:DataNode , wp:Metabolite ;
        rdfs:label          "S-Adenosylmethionine" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/MEFKEPWMEQBLKI-AIRLBKTGSA-N> ;
        dc:identifier       <https://identifiers.org/cas/29908-03-0> ;
        dc:source           "CAS" ;
        dcterms:identifier  "29908-03-0" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP1355_r116584/WP/Interaction/ba331> , <http://rdf.wikipathways.org/Pathway/WP1355_r116584/WP/Interaction/c8d69> , <https://identifiers.org/wikipathways/WP1355_r116584> ;
        dcterms:references  <https://identifiers.org/pubmed/17389618> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:67040> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/31982> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/MEFKEPWMEQBLKI-AIRLBKTGSA-N> ;
        wp:bdbKeggCompound  <https://identifiers.org/kegg.compound/C00019> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID34755> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q27135598> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP1355_r116584/DataNode/dd1> ;
        foaf:page           <https://commonchemistry.cas.org/detail?cas_rn=29908-03-0> .

<https://identifiers.org/pmc/PMC3677916>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed Central" ;
        dcterms:identifier  "PMC3677916" ;
        cito:cites          <https://identifiers.org/wikipathways/WP1355> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/PMC3677916> .

<https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=png&pwTitle=Pathway:WP1355&oldid=116584>
        rdf:type        foaf:Image ;
        dcterms:format  "image/png" .

<https://identifiers.org/ncbigene/450000>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "amt" ;
        dc:identifier       <https://identifiers.org/ncbigene/450000> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "450000" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP1355_r116584> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSDARG00000010862> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/450000> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A9C3Q7> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP1355_r116584/DataNode/d76> , <http://rdf.wikipathways.org/Pathway/WP1355_r116584/DataNode/cc5> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A9C3Q7> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/450000> .

<http://rdf.wikipathways.org/Pathway/WP1355_r116584/WP/Interaction/baa8e>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP1355_r116584> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP1355_r116584/Interaction/baa8e> , <http://rdf.wikipathways.org/Pathway/WP1355_r116584/Interaction/e0952> ;
        wp:participants   <https://identifiers.org/cas/135-16-0> , <https://identifiers.org/ncbigene/58141> , <https://identifiers.org/cas/7444-29-3> ;
        wp:source         <https://identifiers.org/cas/7444-29-3> , <https://identifiers.org/ncbigene/58141> ;
        wp:target         <https://identifiers.org/cas/135-16-0> .

<https://identifiers.org/ncbigene/394052>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "zgc:63647" ;
        dc:identifier       <https://identifiers.org/ncbigene/394052> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "394052" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP1355_r116584/WP/Interaction/afaf6> , <https://identifiers.org/wikipathways/WP1355_r116584> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSDARG00000007421> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/394052> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/F1QZ40> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP1355_r116584/DataNode/d37> , <http://rdf.wikipathways.org/Pathway/WP1355_r116584/DataNode/c5a> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/F1QZ40> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/394052> .

<http://rdf.wikipathways.org/Pathway/WP1355_r116584/WP/Interaction/bfd35>
        rdf:type          wp:Interaction , wp:DirectedInteraction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP1355_r116584> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP1355_r116584/Interaction/ecf5e> , <http://rdf.wikipathways.org/Pathway/WP1355_r116584/Interaction/bfd35> ;
        wp:participants   <https://identifiers.org/ncbigene/260441> , <https://identifiers.org/cas/7444-29-3> , <https://identifiers.org/chebi/CHEBI:12071> ;
        wp:source         <https://identifiers.org/ncbigene/260441> , <https://identifiers.org/cas/7444-29-3> ;
        wp:target         <https://identifiers.org/chebi/CHEBI:12071> .

<https://identifiers.org/cas/134-35-0>
        rdf:type            wp:Metabolite , wp:DataNode ;
        rdfs:label          "5-Methyl Tetrahydrofolate" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/ZNOVTXRBGFNYRX-ZGTCLIOFSA-N> , <https://identifiers.org/inchikey/ZNOVTXRBGFNYRX-ABLWVSNPSA-N> ;
        dc:identifier       <https://identifiers.org/cas/134-35-0> ;
        dc:source           "CAS" ;
        dcterms:identifier  "134-35-0" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP1355_r116584> , <http://rdf.wikipathways.org/Pathway/WP1355_r116584/WP/Interaction/daba8> , <http://rdf.wikipathways.org/Pathway/WP1355_r116584/WP/Interaction/fad8c> ;
        dcterms:references  <https://identifiers.org/pubmed/17389618> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:15641> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/388371> , <https://identifiers.org/chemspider/8001181> ;
        wp:bdbHmdb          <https://identifiers.org/hmdb/HMDB0001396> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/ZNOVTXRBGFNYRX-ABLWVSNPSA-N> , <https://identifiers.org/inchikey/ZNOVTXRBGFNYRX-ZGTCLIOFSA-N> ;
        wp:bdbKeggCompound  <https://identifiers.org/kegg.compound/C00440> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID135415868> , <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID9825434> , <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID439234> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q27290485> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP1355_r116584/DataNode/a42> ;
        foaf:page           <https://commonchemistry.cas.org/detail?cas_rn=134-35-0> .

<https://identifiers.org/ncbigene/100004977>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "mthfd2" ;
        dc:identifier       <https://identifiers.org/ncbigene/100004977> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "100004977" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP1355_r116584> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSDARG00000098646> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/100004977> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q6GMK2> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP1355_r116584/DataNode/a7b> , <http://rdf.wikipathways.org/Pathway/WP1355_r116584/DataNode/f83> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q6GMK2> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/100004977> .

<http://rdf.wikipathways.org/Pathway/WP1355_r116584/WP/Interaction/ba331>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP1355_r116584> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP1355_r116584/Interaction/a054a> , <http://rdf.wikipathways.org/Pathway/WP1355_r116584/Interaction/ba331> ;
        wp:participants   <https://identifiers.org/cas/29908-03-0> , <https://identifiers.org/cas/63-68-3> ;
        wp:source         <https://identifiers.org/cas/63-68-3> ;
        wp:target         <https://identifiers.org/cas/29908-03-0> .

<http://rdf.wikipathways.org/Pathway/WP1355_r116584/WP/Interaction/afaf6>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP1355_r116584> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP1355_r116584/Interaction/e84a0> , <http://rdf.wikipathways.org/Pathway/WP1355_r116584/Interaction/afaf6> ;
        wp:participants   <https://identifiers.org/cas/7444-29-3> , <https://identifiers.org/ncbigene/394052> ;
        wp:source         <https://identifiers.org/ncbigene/394052> ;
        wp:target         <https://identifiers.org/cas/7444-29-3> .

<https://identifiers.org/ncbigene/58141>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "gart" ;
        dc:identifier       <https://identifiers.org/ncbigene/58141> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "58141" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP1355_r116584> , <http://rdf.wikipathways.org/Pathway/WP1355_r116584/WP/Interaction/baa8e> ;
        dcterms:references  <https://identifiers.org/pubmed/17389618> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSDARG00000101089> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/58141> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A0G2KKC3> , <https://identifiers.org/uniprot/A0A0G2KGL2> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP1355_r116584/DataNode/e4e> , <http://rdf.wikipathways.org/Pathway/WP1355_r116584/DataNode/fd1> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A0G2KGL2> , <http://purl.uniprot.org/uniprot/A0A0G2KKC3> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/58141> .

<https://identifiers.org/cas/4033-27-6>
        rdf:type            wp:DataNode , wp:Metabolite ;
        rdfs:label          "Dihydrofolate" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/OZRNSSUDZOLUSN-LBPRGKRZSA-N> ;
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        foaf:page           <https://commonchemistry.cas.org/detail?cas_rn=4033-27-6> .

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        rdfs:label          "5,10-Methenyl Tetrahydrofolate" ;
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<https://identifiers.org/cas/135-16-0>
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        foaf:page           <https://commonchemistry.cas.org/detail?cas_rn=135-16-0> .

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        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/795928> .

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        dc:identifier       <https://identifiers.org/ncbigene/407646> ;
        dc:source           "Entrez Gene" ;
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        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/407646> .

<http://rdf.wikipathways.org/Pathway/WP1355_r116584/WP/Interaction/daba8>
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<https://identifiers.org/ncbigene/569433>
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        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/569433> .

<http://rdf.wikipathways.org/Pathway/WP1355_r116584/WP/Interaction/cefe1>
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        wp:source         <https://identifiers.org/ncbigene/81882> , <https://identifiers.org/cas/4033-27-6> ;
        wp:target         <https://identifiers.org/cas/135-16-0> .

obo:NCBITaxon_7955  obo:NCIT_C179773  "7955" .

<https://identifiers.org/ncbigene/140622>
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        rdfs:label          "atic" ;
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        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/140622> .

<http://rdf.wikipathways.org/Pathway/WP1355_r116584/WP/Interaction/fad8c>
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        wp:target         <https://identifiers.org/cas/134-35-0> .

<https://identifiers.org/ncbigene/30430>
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        rdfs:label          "dnmt1" ;
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        owl:sameAs          <http://purl.uniprot.org/uniprot/F1RCN0> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/30430> .

<https://identifiers.org/chebi/CHEBI:12071>
        rdf:type            wp:DataNode , wp:Metabolite ;
        rdfs:label          "5,10-Methylene Tetrahydrofolate" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/QYNUQALWYRSVHF-ABLWVSNPSA-N> ;
        dc:identifier       <https://identifiers.org/chebi/CHEBI:12071> ;
        dc:source           "ChEBI" ;
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        foaf:page           <https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:12071> .

<https://identifiers.org/wikipathways/WP1355_r116584>
        rdf:type               wp:Pathway , skos:Collection ;
        dc:identifier          <https://identifiers.org/wikipathways/WP1355> ;
        dc:source              "WikiPathways" ;
        dc:title               "One-carbon metabolism"@en ;
        dcterms:description    "This one-carbon metabolism pathway is centered around folate. Folate has two key carbon-carbon double bonds. Saturating one of them yields dihydrofolate (DHF) and adding an additional molecule of hydrogen across the second yields tetrahydrofolate (THF). Folates serve as donors of single carbons in any one of three oxidation states: 5-methyl-THF (CH3THF; reduced), 5,10 methylene-THF (CH2THF; intermediate) and 10-formyl-THF (CHOTHF; oxidized). The single carbon donor CH3THF is used to convert homocysteine into methionine which can then be used to methylate DNA, the donor CH2THF is used (along with a molecule of hydrogen at the site of one of the double bonds) to convert dUMP (deoxyuridylate) into dTMP (thymidylate) and the donor CHOTHF is used to set up ring closure reactions in de novo purine synthesis. CH3THF is the primary methyl-group donor for processes such as DNA methylation reactions. Purines are used both in RNA synthesis and in DNA synthesis and dTMP is synthesized srtictly for DNA synthesis, be it for DNA repair or DNA replication.\nThe folate pathway is central to any study related to DNA methylation, dTMP synthesis or purine synthesis.\n\nDifferential methylation (e.g. hypermethylation of tumor suppressors) as well as disturbances in nucleotide synthesis and repair, are associated with several forms of cancer. There are also indications that hypermethylation is involved in the progression of adenomas to cancer." ;
        dcterms:identifier     "WP1355" ;
        cito:cites             <https://identifiers.org/pubmed/17389618> ;
        wp:isAbout             <http://rdf.wikipathways.org/Pathway/WP1355_r116584> ;
        wp:ontologyTag         wp:Curation:Homology_Converted , obo:PW_0000002 , wp:Curation:AnalysisCollection ;
        wp:organism            obo:NCBITaxon_7955 ;
        wp:organismName        "Danio rerio" ;
        wp:pathwayOntologyTag  obo:PW_0000002 ;
        foaf:img               <https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=png&pwTitle=Pathway:WP1355&oldid=116584> , <https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=svg&pwTitle=Pathway:WP1355&oldid=116584> ;
        foaf:page              <http://www.wikipathways.org/instance/WP1355_r116584> .

<http://rdf.wikipathways.org/Pathway/WP1355_r116584/WP/Interaction/d869c>
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        wp:participants   <https://identifiers.org/cas/6027-13-0> , <https://identifiers.org/cas/979-92-0> ;
        wp:source         <https://identifiers.org/cas/979-92-0> ;
        wp:target         <https://identifiers.org/cas/6027-13-0> .

<http://rdf.wikipathways.org/Pathway/WP1355_r116584/WP/Interaction/f808b>
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        wp:participants   <https://identifiers.org/ncbigene/81882> , <https://identifiers.org/cas/135-16-0> , <https://identifiers.org/cas/59-30-3> ;
        wp:source         <https://identifiers.org/ncbigene/81882> , <https://identifiers.org/cas/59-30-3> ;
        wp:target         <https://identifiers.org/cas/135-16-0> .

<https://identifiers.org/cas/63-68-3>
        rdf:type            wp:Metabolite , wp:DataNode ;
        rdfs:label          "Methionine" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/FFEARJCKVFRZRR-BYPYZUCNSA-N> ;
        dc:identifier       <https://identifiers.org/cas/63-68-3> ;
        dc:source           "CAS" ;
        dcterms:identifier  "63-68-3" ;
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        dcterms:references  <https://identifiers.org/pubmed/17389618> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:16643> , <https://identifiers.org/chebi/CHEBI:57844> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/5907> ;
        wp:bdbHmdb          <https://identifiers.org/hmdb/HMDB0000696> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/FFEARJCKVFRZRR-BYPYZUCNSA-N> ;
        wp:bdbKeggCompound  <https://identifiers.org/kegg.compound/C00073> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID6992087> , <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID6137> ;
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        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP1355_r116584/DataNode/d31> ;
        foaf:page           <https://commonchemistry.cas.org/detail?cas_rn=63-68-3> .

<http://rdf.wikipathways.org/Pathway/WP1355_r116584/WP/Interaction/c5efd>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP1355_r116584> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP1355_r116584/Interaction/c5efd> , <http://rdf.wikipathways.org/Pathway/WP1355_r116584/Interaction/c0133> ;
        wp:participants   <https://identifiers.org/cas/6027-13-0> , <https://identifiers.org/cas/107-43-7> , <https://identifiers.org/ncbigene/322228> ;
        wp:source         <https://identifiers.org/ncbigene/322228> , <https://identifiers.org/cas/107-43-7> ;
        wp:target         <https://identifiers.org/cas/6027-13-0> .

<https://identifiers.org/cas/2800-34-2>
        rdf:type            wp:Metabolite , wp:DataNode ;
        rdfs:label          "10-Formyl Tetrahydrofolate" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/AUFGTPPARQZWDO-YUZLPWPTSA-N> ;
        dc:identifier       <https://identifiers.org/cas/2800-34-2> ;
        dc:source           "CAS" ;
        dcterms:identifier  "2800-34-2" ;
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        dcterms:references  <https://identifiers.org/pubmed/17389618> ;
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        wp:bdbChemspider    <https://identifiers.org/chemspider/109092> ;
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        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID122347> , <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID135450591> ;
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        foaf:page           <https://commonchemistry.cas.org/detail?cas_rn=2800-34-2> .

<https://identifiers.org/cas/979-92-0>
        rdf:type            wp:Metabolite , wp:DataNode ;
        rdfs:label          "S-adenosylhomocysteine" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/ZJUKTBDSGOFHSH-WFMPWKQPSA-N> ;
        dc:identifier       <https://identifiers.org/cas/979-92-0> ;
        dc:source           "CAS" ;
        dcterms:identifier  "979-92-0" ;
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        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:57856> , <https://identifiers.org/chebi/CHEBI:16680> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/388301> ;
        wp:bdbHmdb          <https://identifiers.org/hmdb/HMDB0000939> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/ZJUKTBDSGOFHSH-WFMPWKQPSA-N> ;
        wp:bdbKeggCompound  <https://identifiers.org/kegg.compound/C00021> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID25246222> , <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID439155> ;
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        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP1355_r116584/DataNode/d97> ;
        foaf:page           <https://commonchemistry.cas.org/detail?cas_rn=979-92-0> .

<https://identifiers.org/ncbigene/317744>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "dnmt4" ;
        dc:identifier       <https://identifiers.org/ncbigene/317744> ;
        dc:source           "Entrez Gene" ;
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        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSDARG00000036791> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/317744> ;
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        owl:sameAs          <http://purl.uniprot.org/uniprot/Q588C6> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/317744> .

<https://identifiers.org/ncbigene/334195>
        rdf:type            wp:DataNode , wp:GeneProduct ;
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        dc:source           "Entrez Gene" ;
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        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSDARG00000039605> ;
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        owl:sameAs          <http://purl.uniprot.org/uniprot/Q7ZW04> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/334195> .

<https://identifiers.org/ncbigene/322228>
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        rdfs:label          "bhmt" ;
        dc:identifier       <https://identifiers.org/ncbigene/322228> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "322228" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP1355_r116584/WP/Interaction/c5efd> , <https://identifiers.org/wikipathways/WP1355_r116584> ;
        dcterms:references  <https://identifiers.org/pubmed/17389618> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSDARG00000013430> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/322228> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A2R8PWR1> , <https://identifiers.org/uniprot/F1QU55> ;
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        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A2R8PWR1> , <http://purl.uniprot.org/uniprot/F1QU55> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/322228> .

<http://rdf.wikipathways.org/Pathway/WP1355_r116584/WP/Interaction/f04fe>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
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        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP1355_r116584/Interaction/f04fe> , <http://rdf.wikipathways.org/Pathway/WP1355_r116584/Interaction/ab237> ;
        wp:participants   <https://identifiers.org/chebi/CHEBI:12071> , <https://identifiers.org/ncbigene/81540> , <https://identifiers.org/cas/4033-27-6> ;
        wp:source         <https://identifiers.org/ncbigene/81540> , <https://identifiers.org/chebi/CHEBI:12071> ;
        wp:target         <https://identifiers.org/cas/4033-27-6> .

<http://rdf.wikipathways.org/Pathway/WP1355_r116584/WP/Interaction/c5975>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP1355_r116584> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP1355_r116584/Interaction/c03f1> , <http://rdf.wikipathways.org/Pathway/WP1355_r116584/Interaction/c5975> ;
        wp:participants   <https://identifiers.org/chebi/CHEBI:12071> , <https://identifiers.org/cas/135-16-0> ;
        wp:source         <https://identifiers.org/cas/135-16-0> ;
        wp:target         <https://identifiers.org/chebi/CHEBI:12071> .

<https://identifiers.org/ncbigene/100144628>
        rdf:type            wp:DataNode , wp:GeneProduct ;
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        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSDARG00000104414> ;
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        wp:bdbUniprot       <https://identifiers.org/uniprot/A9LDD9> ;
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        owl:sameAs          <http://purl.uniprot.org/uniprot/A9LDD9> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/100144628> .

<https://identifiers.org/ncbigene/394021>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "shmt1" ;
        dc:identifier       <https://identifiers.org/ncbigene/394021> ;
        dc:source           "Entrez Gene" ;
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        dcterms:references  <https://identifiers.org/pubmed/17389618> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSDARG00000052816> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/394021> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/E9QEK5> , <https://identifiers.org/uniprot/Q6NYR0> , <https://identifiers.org/uniprot/E9QBE1> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP1355_r116584/DataNode/d3d> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q6NYR0> , <http://purl.uniprot.org/uniprot/E9QBE1> , <http://purl.uniprot.org/uniprot/E9QEK5> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/394021> .

<http://rdf.wikipathways.org/Pathway/WP1355_r116584/WP/Interaction/c2b59>
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        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP1355_r116584/Interaction/a7f2d> , <http://rdf.wikipathways.org/Pathway/WP1355_r116584/Interaction/c2b59> ;
        wp:participants   <https://identifiers.org/cas/2800-34-2> , <https://identifiers.org/cas/135-16-0> ;
        wp:source         <https://identifiers.org/cas/135-16-0> ;
        wp:target         <https://identifiers.org/cas/2800-34-2> .

<https://identifiers.org/ncbigene/553189>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "dnmt6" ;
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        dc:source           "Entrez Gene" ;
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        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSDARG00000015566> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/553189> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/F1R1K5> , <https://identifiers.org/uniprot/B3DGZ8> , <https://identifiers.org/uniprot/Q588C4> ;
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        owl:sameAs          <http://purl.uniprot.org/uniprot/B3DGZ8> , <http://purl.uniprot.org/uniprot/F1R1K5> , <http://purl.uniprot.org/uniprot/Q588C4> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/553189> .

<https://identifiers.org/ncbigene/81882>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "dhfr" ;
        dc:identifier       <https://identifiers.org/ncbigene/81882> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "81882" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP1355_r116584> , <http://rdf.wikipathways.org/Pathway/WP1355_r116584/WP/Interaction/c422d> , <http://rdf.wikipathways.org/Pathway/WP1355_r116584/WP/Interaction/cefe1> , <http://rdf.wikipathways.org/Pathway/WP1355_r116584/WP/Interaction/f808b> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSDARG00000004251> ;
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        wp:bdbUniprot       <https://identifiers.org/uniprot/A2BGQ1> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP1355_r116584/DataNode/fea> , <http://rdf.wikipathways.org/Pathway/WP1355_r116584/DataNode/a74c2> , <http://rdf.wikipathways.org/Pathway/WP1355_r116584/DataNode/fe0c8> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A2BGQ1> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/81882> .

<https://identifiers.org/pubmed/17389618>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
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        dcterms:isPartOf    <https://identifiers.org/cas/63-68-3> , <https://identifiers.org/cas/134-35-0> , <https://identifiers.org/ncbigene/30430> , <https://identifiers.org/cas/135-16-0> , <https://identifiers.org/chebi/CHEBI:12071> , <https://identifiers.org/cas/107-43-7> , <https://identifiers.org/ncbigene/407646> , <https://identifiers.org/ncbigene/394021> , <https://identifiers.org/ncbigene/795928> , <https://identifiers.org/ncbigene/378847> , <https://identifiers.org/cas/6027-13-0> , <https://identifiers.org/cas/59-30-3> , <https://identifiers.org/cas/2800-34-2> , <https://identifiers.org/cas/979-92-0> , <https://identifiers.org/ncbigene/140622> , <https://identifiers.org/ncbigene/260441> , <https://identifiers.org/cas/25513-46-6> , <https://identifiers.org/cas/29908-03-0> , <https://identifiers.org/cas/4033-27-6> , <https://identifiers.org/ncbigene/322228> , <https://identifiers.org/ncbigene/560667> , <https://identifiers.org/cas/7444-29-3> , <https://identifiers.org/ncbigene/58141> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/17389618> .

<http://rdf.wikipathways.org/Pathway/WP1355_r116584/WP/Interaction/c6733>
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        wp:participants   <https://identifiers.org/cas/7444-29-3> , <https://identifiers.org/cas/2800-34-2> ;
        wp:source         <https://identifiers.org/cas/2800-34-2> ;
        wp:target         <https://identifiers.org/cas/7444-29-3> .

<http://rdf.wikipathways.org/Pathway/WP1355_r116584/WP/Interaction/c8d69>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP1355_r116584> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP1355_r116584/Interaction/c993d> , <http://rdf.wikipathways.org/Pathway/WP1355_r116584/Interaction/c8d69> ;
        wp:participants   <https://identifiers.org/cas/979-92-0> , <https://identifiers.org/cas/29908-03-0> ;
        wp:source         <https://identifiers.org/cas/29908-03-0> ;
        wp:target         <https://identifiers.org/cas/979-92-0> .

<https://identifiers.org/ncbigene/556680>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "zgc:152651" ;
        dc:identifier       <https://identifiers.org/ncbigene/556680> ;
        dc:source           "Entrez Gene" ;
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        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP1355_r116584> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSDARG00000005448> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/556680> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/F1QJ58> ;
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        owl:sameAs          <http://purl.uniprot.org/uniprot/F1QJ58> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/556680> .

<https://identifiers.org/ncbigene/387530>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "ahcy" ;
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        dc:source           "Entrez Gene" ;
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        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSDARG00000005191> ;
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        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP1355_r116584/DataNode/fa9> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q803T5> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/387530> .

<https://identifiers.org/wikipathways/WP1355>
        pav:hasVersion  <https://identifiers.org/wikipathways/WP1355_r116584> .

<https://identifiers.org/ncbigene/378847>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "mtr" ;
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        dc:source           "Entrez Gene" ;
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        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSDARG00000104906> ;
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        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A0G2L2R7> ;
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        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A0G2L2R7> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/378847> .

<https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=svg&pwTitle=Pathway:WP1355&oldid=116584>
        rdf:type        foaf:Image ;
        dcterms:format  "image/svg+xml" .

<https://identifiers.org/ncbigene/394240>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "ahcyl2" ;
        dc:identifier       <https://identifiers.org/ncbigene/394240> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "394240" ;
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        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSDARG00000039343> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/394240> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/X1WBB7> , <https://identifiers.org/uniprot/Q6PC06> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP1355_r116584/DataNode/ca3> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q6PC06> , <http://purl.uniprot.org/uniprot/X1WBB7> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/394240> .

<https://identifiers.org/ncbigene/260441>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "mthfd1" ;
        dc:identifier       <https://identifiers.org/ncbigene/260441> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "260441" ;
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        dcterms:references  <https://identifiers.org/pubmed/17389618> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSDARG00000040492> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/260441> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/F1QXP5> , <https://identifiers.org/uniprot/K7DYD3> , <https://identifiers.org/uniprot/K7DYA3> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP1355_r116584/DataNode/a92> , <http://rdf.wikipathways.org/Pathway/WP1355_r116584/DataNode/ba6> , <http://rdf.wikipathways.org/Pathway/WP1355_r116584/DataNode/e02> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/K7DYA3> , <http://purl.uniprot.org/uniprot/F1QXP5> , <http://purl.uniprot.org/uniprot/K7DYD3> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/260441> .

<http://rdf.wikipathways.org/Pathway/WP1355_r116584/WP/Interaction/f11dc>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP1355_r116584> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP1355_r116584/Interaction/f6d39> , <http://rdf.wikipathways.org/Pathway/WP1355_r116584/Interaction/f11dc> ;
        wp:participants   <https://identifiers.org/cas/63-68-3> , <https://identifiers.org/cas/6027-13-0> ;
        wp:source         <https://identifiers.org/cas/6027-13-0> ;
        wp:target         <https://identifiers.org/cas/63-68-3> .

<http://rdf.wikipathways.org/Pathway/WP1355_r116584/WP/Interaction/fe74f>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP1355_r116584> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP1355_r116584/Interaction/bd136> , <http://rdf.wikipathways.org/Pathway/WP1355_r116584/Interaction/fe74f> ;
        wp:participants   <https://identifiers.org/cas/7444-29-3> , <https://identifiers.org/ncbigene/100003075> ;
        wp:source         <https://identifiers.org/ncbigene/100003075> ;
        wp:target         <https://identifiers.org/cas/7444-29-3> .

<https://identifiers.org/cas/6027-13-0>
        rdf:type            wp:Metabolite , wp:DataNode ;
        rdfs:label          "Homocysteine" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/FFFHZYDWPBMWHY-VKHMYHEASA-N> ;
        dc:identifier       <https://identifiers.org/cas/6027-13-0> ;
        dc:source           "CAS" ;
        dcterms:identifier  "6027-13-0" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP1355_r116584/WP/Interaction/c5efd> , <https://identifiers.org/wikipathways/WP1355_r116584> , <http://rdf.wikipathways.org/Pathway/WP1355_r116584/WP/Interaction/f11dc> , <http://rdf.wikipathways.org/Pathway/WP1355_r116584/WP/Interaction/d869c> ;
        dcterms:references  <https://identifiers.org/pubmed/17389618> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:58199> , <https://identifiers.org/chebi/CHEBI:17588> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/82666> ;
        wp:bdbHmdb          <https://identifiers.org/hmdb/HMDB0000742> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/FFFHZYDWPBMWHY-VKHMYHEASA-N> ;
        wp:bdbKeggCompound  <https://identifiers.org/kegg.compound/C00155> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID91552> , <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID6971015> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q26992833> , <http://www.wikidata.org/entity/Q106345493> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP1355_r116584/DataNode/f77> ;
        foaf:page           <https://commonchemistry.cas.org/detail?cas_rn=6027-13-0> .
