@prefix biopax:  <http://www.biopax.org/release/biopax-level3.owl#> .
@prefix cito:    <http://purl.org/spar/cito/> .
@prefix dc:      <http://purl.org/dc/elements/1.1/> .
@prefix dcterms: <http://purl.org/dc/terms/> .
@prefix foaf:    <http://xmlns.com/foaf/0.1/> .
@prefix freq:    <http://purl.org/cld/freq/> .
@prefix gpml:    <http://vocabularies.wikipathways.org/gpml#> .
@prefix obo:     <http://purl.obolibrary.org/obo/> .
@prefix owl:     <http://www.w3.org/2002/07/owl#> .
@prefix pav:     <http://purl.org/pav/> .
@prefix prov:    <http://www.w3.org/ns/prov#> .
@prefix rdf:     <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix rdfs:    <http://www.w3.org/2000/01/rdf-schema#> .
@prefix skos:    <http://www.w3.org/2004/02/skos/core#> .
@prefix void:    <http://rdfs.org/ns/void#> .
@prefix wp:      <http://vocabularies.wikipathways.org/wp#> .
@prefix wprdf:   <http://rdf.wikipathways.org/> .
@prefix xsd:     <http://www.w3.org/2001/XMLSchema#> .

<http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/ide23d1db>
        rdf:type          wp:Catalysis , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP5216_r126981> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP5216_r126981/Interaction/ide23d1db> ;
        wp:participants   <https://identifiers.org/ncbigene/5223> , <http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/idd471abf1> ;
        wp:source         <https://identifiers.org/ncbigene/5223> ;
        wp:target         <http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/idd471abf1> .

<https://identifiers.org/ensembl/ENSG00000128052>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "VEGFR2" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000128052> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000128052" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/idac528ce> , <https://identifiers.org/wikipathways/WP5216_r126981> , <http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/ec223> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000128052> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/3791> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/KDR> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/P35968> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18028241> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5216_r126981/DataNode/f8cba> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P35968> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000128052> .

<http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/id4c738f7e>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP5216_r126981> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP5216_r126981/Interaction/id4c738f7e> ;
        wp:participants   <https://identifiers.org/ncbigene/2538> , <https://identifiers.org/ncbigene/7874> ;
        wp:source         <https://identifiers.org/ncbigene/7874> ;
        wp:target         <https://identifiers.org/ncbigene/2538> .

<http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/ide94d83f9>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP5216_r126981> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP5216_r126981/Interaction/ide94d83f9> ;
        wp:participants   <https://identifiers.org/chebi/CHEBI:17138> , <https://identifiers.org/chebi/CHEBI:32966> ;
        wp:source         <https://identifiers.org/chebi/CHEBI:32966> ;
        wp:target         <https://identifiers.org/chebi/CHEBI:17138> .

<http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/id431f798b>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP5216_r126981> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP5216_r126981/Interaction/id431f798b> ;
        wp:participants   <https://identifiers.org/chebi/CHEBI:4167> , <https://identifiers.org/chebi/CHEBI:4170> ;
        wp:source         <https://identifiers.org/chebi/CHEBI:4170> ;
        wp:target         <https://identifiers.org/chebi/CHEBI:4167> .

<https://identifiers.org/chebi/CHEBI:24996>
        rdf:type            wp:DataNode , wp:Metabolite ;
        rdfs:label          "Lactate" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/JVTAAEKCZFNVCJ-UHFFFAOYSA-N> ;
        dc:identifier       <https://identifiers.org/chebi/CHEBI:24996> ;
        dc:source           "ChEBI" ;
        dcterms:identifier  "24996" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP5216_r126981> , <http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/id90f1ae6d> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:24996> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/82564> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/JVTAAEKCZFNVCJ-UHFFFAOYSA-M> ;
        wp:bdbKeggCompound  <https://identifiers.org/kegg.compound/C01432> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID91435> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q27895931> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5216_r126981/DataNode/deb1c> ;
        foaf:page           <https://www.ebi.ac.uk/chebi/searchId.do?chebiId=24996> .

<https://identifiers.org/ensembl/ENSG00000136997>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "c-Myc" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000136997> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000136997" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/idbecdfda> , <https://identifiers.org/wikipathways/WP5216_r126981> , <http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/id7d485c38> , <http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/id145f76be> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000136997> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/4609> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/MYC> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q16591> , <https://identifiers.org/uniprot/P01106> , <https://identifiers.org/uniprot/A0A0B4J1R1> , <https://identifiers.org/uniprot/H0YBG3> , <https://identifiers.org/uniprot/A0A494C1T8> , <https://identifiers.org/uniprot/Q14899> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q20969939> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5216_r126981/DataNode/c3dbb> , <http://rdf.wikipathways.org/Pathway/WP5216_r126981/DataNode/cb03f> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A494C1T8> , <http://purl.uniprot.org/uniprot/H0YBG3> , <http://purl.uniprot.org/uniprot/Q16591> , <http://purl.uniprot.org/uniprot/Q14899> , <http://purl.uniprot.org/uniprot/A0A0B4J1R1> , <http://purl.uniprot.org/uniprot/P01106> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000136997> .

<https://identifiers.org/ncbigene/207>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "AKT1" ;
        dc:identifier       <https://identifiers.org/ncbigene/207> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "207" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/idd414123e> , <http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/idf42cce1f> , <http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/id48664eb4> , <https://identifiers.org/wikipathways/WP5216_r126981> , <http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/id92d66332> , <http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/ida41adcbe> , <http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/idd62e7732> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000142208> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/207> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/AKT1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/P31749> , <https://identifiers.org/uniprot/A0A804HJM6> , <https://identifiers.org/uniprot/B0LPE5> , <https://identifiers.org/uniprot/G3V2I6> , <https://identifiers.org/uniprot/A0A087WY56> , <https://identifiers.org/uniprot/G3V3X1> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5216_r126981/DataNode/b007e> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/G3V2I6> , <http://purl.uniprot.org/uniprot/B0LPE5> , <http://purl.uniprot.org/uniprot/A0A804HJM6> , <http://purl.uniprot.org/uniprot/A0A087WY56> , <http://purl.uniprot.org/uniprot/P31749> , <http://purl.uniprot.org/uniprot/G3V3X1> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/207> .

<https://identifiers.org/chebi/CHEBI:17050>
        rdf:type            wp:Metabolite , wp:DataNode ;
        rdfs:label          "3PG" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/OSJPPGNTCRNQQC-UHFFFAOYSA-N> ;
        dc:identifier       <https://identifiers.org/chebi/CHEBI:17050> ;
        dc:source           "ChEBI" ;
        dcterms:identifier  "17050" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP5216_r126981> , <http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/id91684b77> , <http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/idd471abf1> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:17050> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/704> ;
        wp:bdbHmdb          <https://identifiers.org/hmdb/HMDB0000807> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/OSJPPGNTCRNQQC-UHFFFAOYSA-N> ;
        wp:bdbKeggCompound  <https://identifiers.org/kegg.compound/C00597> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID724> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q32904835> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5216_r126981/DataNode/b5a74> ;
        foaf:page           <https://www.ebi.ac.uk/chebi/searchId.do?chebiId=17050> .

<http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/ida41adcbe>
        rdf:type          wp:Inhibition , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP5216_r126981> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP5216_r126981/Interaction/ida41adcbe> ;
        wp:participants   <https://identifiers.org/ncbigene/2308> , <https://identifiers.org/ncbigene/207> ;
        wp:source         <https://identifiers.org/ncbigene/207> ;
        wp:target         <https://identifiers.org/ncbigene/2308> .

<http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/id25d9d322>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP5216_r126981> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP5216_r126981/Interaction/id25d9d322> ;
        wp:participants   <https://identifiers.org/ncbigene/5223> , <https://identifiers.org/ncbigene/78990> ;
        wp:source         <https://identifiers.org/ncbigene/78990> ;
        wp:target         <https://identifiers.org/ncbigene/5223> .

<http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/ide7664178>
        rdf:type          wp:Catalysis , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP5216_r126981> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP5216_r126981/Interaction/ide7664178> ;
        wp:participants   <https://identifiers.org/ncbigene/3939> , <http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/id90f1ae6d> ;
        wp:source         <https://identifiers.org/ncbigene/3939> ;
        wp:target         <http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/id90f1ae6d> .

<http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/id90f1ae6d>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP5216_r126981> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP5216_r126981/Interaction/id90f1ae6d> ;
        wp:participants   <https://identifiers.org/chebi/CHEBI:24996> , <https://identifiers.org/chebi/CHEBI:15361> ;
        wp:source         <https://identifiers.org/chebi/CHEBI:15361> ;
        wp:target         <https://identifiers.org/chebi/CHEBI:24996> .

<http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/idb573a17b>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP5216_r126981> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP5216_r126981/Interaction/idb573a17b> ;
        wp:participants   <https://identifiers.org/chebi/CHEBI:89363> , <https://identifiers.org/chebi/CHEBI:17138> ;
        wp:source         <https://identifiers.org/chebi/CHEBI:17138> ;
        wp:target         <https://identifiers.org/chebi/CHEBI:89363> .

<https://identifiers.org/pubmed/23216836>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "23216836" ;
        dcterms:isPartOf    <https://identifiers.org/ensembl/ENSG00000112715> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q38065328> ;
        owl:sameAs          <https://doi.org/10.1111%2FJOIM.12019> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/23216836> .

<https://identifiers.org/ensembl/ENSG00000121879>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "PI3K" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000121879> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000121879" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP5216_r126981> , <http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/ec223> , <http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/idd414123e> ;
        dcterms:references  <https://identifiers.org/pubmed/30742905> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000121879> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/5290> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/PIK3CA> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/P42336> , <https://identifiers.org/uniprot/A0A2R8Y2F6> , <https://identifiers.org/uniprot/A0A6Q8PGV1> , <https://identifiers.org/uniprot/C9JAM9> , <https://identifiers.org/uniprot/C9J951> , <https://identifiers.org/uniprot/A0A6Q8PGN9> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q14887700> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5216_r126981/DataNode/d1cdc> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/C9J951> , <http://purl.uniprot.org/uniprot/C9JAM9> , <http://purl.uniprot.org/uniprot/P42336> , <http://purl.uniprot.org/uniprot/A0A2R8Y2F6> , <http://purl.uniprot.org/uniprot/A0A6Q8PGV1> , <http://purl.uniprot.org/uniprot/A0A6Q8PGN9> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000121879> .

<https://identifiers.org/wikipathways/WP5216>
        pav:hasVersion  <https://identifiers.org/wikipathways/WP5216_r126981> .

<http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/ec223>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP5216_r126981> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP5216_r126981/Interaction/ec223> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000121879> , <https://identifiers.org/ensembl/ENSG00000128052> ;
        wp:source         <https://identifiers.org/ensembl/ENSG00000128052> ;
        wp:target         <https://identifiers.org/ensembl/ENSG00000121879> .

<http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/ide5cafcd2>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP5216_r126981> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP5216_r126981/Interaction/ide5cafcd2> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000159399> , <https://identifiers.org/ncbigene/78990> ;
        wp:source         <https://identifiers.org/ncbigene/78990> ;
        wp:target         <https://identifiers.org/ensembl/ENSG00000159399> .

<https://identifiers.org/ncbigene/11338>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "U2AF2" ;
        dc:identifier       <https://identifiers.org/ncbigene/11338> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "11338" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/id478f171b> , <https://identifiers.org/wikipathways/WP5216_r126981> , <http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/ide8a854e> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000063244> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/11338> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/U2AF2> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/K7ELP8> , <https://identifiers.org/uniprot/P26368> , <https://identifiers.org/uniprot/M0QYQ9> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5216_r126981/DataNode/f36f0> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/M0QYQ9> , <http://purl.uniprot.org/uniprot/P26368> , <http://purl.uniprot.org/uniprot/K7ELP8> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/11338> .

<https://identifiers.org/chebi/CHEBI:4167>
        rdf:type            wp:Metabolite , wp:DataNode ;
        rdfs:label          "Glucose" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/WQZGKKKJIJFFOK-GASJEMHNSA-N> ;
        dc:identifier       <https://identifiers.org/chebi/CHEBI:4167> ;
        dc:source           "ChEBI" ;
        dcterms:identifier  "4167" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/id63384f0d> , <https://identifiers.org/wikipathways/WP5216_r126981> , <http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/id431f798b> , <http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/idd0b23cb0> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:4167> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/5589> ;
        wp:bdbHmdb          <https://identifiers.org/hmdb/HMDB0304632> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/WQZGKKKJIJFFOK-GASJEMHNSA-N> ;
        wp:bdbKeggCompound  <https://identifiers.org/kegg.compound/C00031> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID5793> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q23905964> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5216_r126981/DataNode/defb2> , <http://rdf.wikipathways.org/Pathway/WP5216_r126981/DataNode/fb4c7> ;
        foaf:page           <https://www.ebi.ac.uk/chebi/searchId.do?chebiId=4167> .

<https://identifiers.org/chebi/CHEBI:18021>
        rdf:type            wp:Metabolite , wp:DataNode ;
        rdfs:label          "PEP" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/DTBNBXWJWCWCIK-UHFFFAOYSA-N> ;
        dc:identifier       <https://identifiers.org/chebi/CHEBI:18021> ;
        dc:source           "ChEBI" ;
        dcterms:identifier  "18021" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/idfab8b1f7> , <https://identifiers.org/wikipathways/WP5216_r126981> , <http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/id66afe83a> , <http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/idf26117c4> ;
        dcterms:references  <https://identifiers.org/pubmed/21591214> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:18021> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/6076> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/DTBNBXWJWCWCIK-UHFFFAOYSA-M> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID6315> , <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID638308> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q27102770> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5216_r126981/DataNode/e68d5> ;
        foaf:page           <https://www.ebi.ac.uk/chebi/searchId.do?chebiId=18021> .

<https://identifiers.org/ncbigene/2308>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "FOXO1" ;
        dc:identifier       <https://identifiers.org/ncbigene/2308> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "2308" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/ida41adcbe> , <http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/id581f8ac9> , <https://identifiers.org/wikipathways/WP5216_r126981> , <http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/id4a21908d> , <http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/idfe89f049> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000150907> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/2308> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/FOXO1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q12778> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5216_r126981/DataNode/aa632> , <http://rdf.wikipathways.org/Pathway/WP5216_r126981/DataNode/a6eaf> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q12778> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/2308> .

<http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/idc8d05b6f>
        rdf:type          wp:Catalysis , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP5216_r126981> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP5216_r126981/Interaction/idc8d05b6f> ;
        wp:participants   <https://identifiers.org/hgnc.symbol/FBP1> , <http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/id823acbbd> ;
        wp:source         <https://identifiers.org/hgnc.symbol/FBP1> ;
        wp:target         <http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/id823acbbd> .

<http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/id581f8ac9>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP5216_r126981> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP5216_r126981/Interaction/id581f8ac9> ;
        wp:participants   <https://identifiers.org/ncbigene/2538> , <https://identifiers.org/ncbigene/2308> ;
        wp:source         <https://identifiers.org/ncbigene/2308> ;
        wp:target         <https://identifiers.org/ncbigene/2538> .

<https://identifiers.org/ensembl/ENSG00000134086>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "VHL" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000134086> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000134086" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP5216_r126981> , <http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/id80aeae06> , <http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/id8ec4ad54> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000134086> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/7428> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/VHL> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A024R2F2> , <https://identifiers.org/uniprot/A0A8Q3WL21> , <https://identifiers.org/uniprot/A0A8Q3SIA6> , <https://identifiers.org/uniprot/P40337> , <https://identifiers.org/uniprot/A0A0S2Z4K1> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q14905473> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5216_r126981/DataNode/cb56f> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A0S2Z4K1> , <http://purl.uniprot.org/uniprot/A0A8Q3WL21> , <http://purl.uniprot.org/uniprot/A0A024R2F2> , <http://purl.uniprot.org/uniprot/P40337> , <http://purl.uniprot.org/uniprot/A0A8Q3SIA6> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000134086> .

<http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/idbecdfda>
        rdf:type          wp:TranscriptionTranslation , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP5216_r126981> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP5216_r126981/Interaction/idbecdfda> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000117394> , <https://identifiers.org/ensembl/ENSG00000136997> ;
        wp:source         <https://identifiers.org/ensembl/ENSG00000136997> ;
        wp:target         <https://identifiers.org/ensembl/ENSG00000117394> .

<http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/id66afe83a>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP5216_r126981> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP5216_r126981/Interaction/id66afe83a> ;
        wp:participants   <https://identifiers.org/chebi/CHEBI:18021> , <https://identifiers.org/chebi/CHEBI:24344> ;
        wp:source         <https://identifiers.org/chebi/CHEBI:24344> ;
        wp:target         <https://identifiers.org/chebi/CHEBI:18021> .

<https://identifiers.org/ncbigene/57695>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "USP37" ;
        dc:identifier       <https://identifiers.org/ncbigene/57695> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "57695" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/id58af8d42> , <https://identifiers.org/wikipathways/WP5216_r126981> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000135913> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/57695> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/USP37> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q86T82> , <https://identifiers.org/uniprot/Q86W68> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5216_r126981/DataNode/b0e5f> , <http://rdf.wikipathways.org/Pathway/WP5216_r126981/DataNode/e2316> , <http://rdf.wikipathways.org/Pathway/WP5216_r126981/DataNode/c758b> , <http://rdf.wikipathways.org/Pathway/WP5216_r126981/DataNode/c85f5> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q86T82> , <http://purl.uniprot.org/uniprot/Q86W68> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/57695> .

<http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/id80aeae06>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP5216_r126981> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP5216_r126981/Interaction/id80aeae06> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000134086> , <https://identifiers.org/ncbigene/51633> ;
        wp:source         <https://identifiers.org/ncbigene/51633> ;
        wp:target         <https://identifiers.org/ensembl/ENSG00000134086> .

<http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/idac23cbf3>
        rdf:type          wp:Catalysis , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP5216_r126981> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP5216_r126981/Interaction/idac23cbf3> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000117394> , <http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/idd0b23cb0> ;
        wp:source         <https://identifiers.org/ensembl/ENSG00000117394> ;
        wp:target         <http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/idd0b23cb0> .

<https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=svg&pwTitle=Pathway:WP5216&oldid=126981>
        rdf:type        foaf:Image ;
        dcterms:format  "image/svg+xml" .

<https://identifiers.org/ncbigene/3939>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "LDHA" ;
        dc:identifier       <https://identifiers.org/ncbigene/3939> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "3939" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/id58af8d42> , <http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/ide7664178> , <http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/id242a7a14> , <https://identifiers.org/wikipathways/WP5216_r126981> , <http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/id145f76be> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000134333> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/3939> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/LDHA> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/F5GZQ4> , <https://identifiers.org/uniprot/F5H6W8> , <https://identifiers.org/uniprot/F5GXU1> , <https://identifiers.org/uniprot/F5H5J4> , <https://identifiers.org/uniprot/F5GXC7> , <https://identifiers.org/uniprot/V9HWB9> , <https://identifiers.org/uniprot/P00338> , <https://identifiers.org/uniprot/F5H8H6> , <https://identifiers.org/uniprot/F5GXH2> , <https://identifiers.org/uniprot/F5GYU2> , <https://identifiers.org/uniprot/F5GXY2> , <https://identifiers.org/uniprot/F5GWW2> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5216_r126981/DataNode/c3fc1> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/F5GZQ4> , <http://purl.uniprot.org/uniprot/F5H6W8> , <http://purl.uniprot.org/uniprot/F5GXH2> , <http://purl.uniprot.org/uniprot/P00338> , <http://purl.uniprot.org/uniprot/F5GXC7> , <http://purl.uniprot.org/uniprot/V9HWB9> , <http://purl.uniprot.org/uniprot/F5GXU1> , <http://purl.uniprot.org/uniprot/F5GYU2> , <http://purl.uniprot.org/uniprot/F5H8H6> , <http://purl.uniprot.org/uniprot/F5GXY2> , <http://purl.uniprot.org/uniprot/F5H5J4> , <http://purl.uniprot.org/uniprot/F5GWW2> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/3939> .

<https://identifiers.org/ncbigene/3091>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "HIF-1α" ;
        dc:identifier       <https://identifiers.org/ncbigene/3091> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "3091" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/id242a7a14> , <http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/ideaa5b55b> , <http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/iddaf4e1c6> , <https://identifiers.org/wikipathways/WP5216_r126981> , <http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/id8ec4ad54> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000100644> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/3091> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/HIF1A> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/D0VY79> , <https://identifiers.org/uniprot/Q16665> , <https://identifiers.org/uniprot/A8MYV6> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5216_r126981/DataNode/aa994> , <http://rdf.wikipathways.org/Pathway/WP5216_r126981/DataNode/dbe8a> , <http://rdf.wikipathways.org/Pathway/WP5216_r126981/DataNode/e1f75> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q16665> , <http://purl.uniprot.org/uniprot/A8MYV6> , <http://purl.uniprot.org/uniprot/D0VY79> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/3091> .

<https://identifiers.org/ncbigene/57646>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "USP28" ;
        dc:identifier       <https://identifiers.org/ncbigene/57646> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "57646" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP5216_r126981> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000048028> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/57646> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/USP28> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A8V8TLZ9> , <https://identifiers.org/uniprot/F5H2G4> , <https://identifiers.org/uniprot/A0A8V8TKW5> , <https://identifiers.org/uniprot/H0YG96> , <https://identifiers.org/uniprot/G3V1N5> , <https://identifiers.org/uniprot/H0YFA0> , <https://identifiers.org/uniprot/F5H6Q3> , <https://identifiers.org/uniprot/H0YH19> , <https://identifiers.org/uniprot/B4E3L3> , <https://identifiers.org/uniprot/H0YFX3> , <https://identifiers.org/uniprot/Q96RU2> , <https://identifiers.org/uniprot/F5GZ74> , <https://identifiers.org/uniprot/H0YFT9> , <https://identifiers.org/uniprot/H0YFD7> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5216_r126981/DataNode/c7abf> , <http://rdf.wikipathways.org/Pathway/WP5216_r126981/DataNode/e8885> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/H0YFT9> , <http://purl.uniprot.org/uniprot/F5H2G4> , <http://purl.uniprot.org/uniprot/Q96RU2> , <http://purl.uniprot.org/uniprot/A0A8V8TKW5> , <http://purl.uniprot.org/uniprot/H0YFA0> , <http://purl.uniprot.org/uniprot/F5GZ74> , <http://purl.uniprot.org/uniprot/G3V1N5> , <http://purl.uniprot.org/uniprot/H0YG96> , <http://purl.uniprot.org/uniprot/H0YFD7> , <http://purl.uniprot.org/uniprot/B4E3L3> , <http://purl.uniprot.org/uniprot/A0A8V8TLZ9> , <http://purl.uniprot.org/uniprot/H0YH19> , <http://purl.uniprot.org/uniprot/H0YFX3> , <http://purl.uniprot.org/uniprot/F5H6Q3> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/57646> .

<http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/idf42cce1f>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP5216_r126981> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP5216_r126981/Interaction/idf42cce1f> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000159399> , <https://identifiers.org/ncbigene/207> ;
        wp:source         <https://identifiers.org/ncbigene/207> ;
        wp:target         <https://identifiers.org/ensembl/ENSG00000159399> .

<http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/id356e003f>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP5216_r126981> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP5216_r126981/Interaction/id356e003f> ;
        wp:participants   <https://identifiers.org/chebi/CHEBI:32966> , <https://identifiers.org/chebi/CHEBI:61527> ;
        wp:source         <https://identifiers.org/chebi/CHEBI:61527> ;
        wp:target         <https://identifiers.org/chebi/CHEBI:32966> .

<http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/id4137c26f>
        rdf:type          wp:Catalysis , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP5216_r126981> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP5216_r126981/Interaction/id4137c26f> ;
        wp:participants   <https://identifiers.org/ncbigene/5230> , <http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/id91684b77> ;
        wp:source         <https://identifiers.org/ncbigene/5230> ;
        wp:target         <http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/id91684b77> .

<http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/id42ad3a5d>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP5216_r126981> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP5216_r126981/Interaction/id42ad3a5d> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000112715> , <https://identifiers.org/ncbigene/10869> ;
        wp:source         <https://identifiers.org/ncbigene/10869> ;
        wp:target         <https://identifiers.org/ensembl/ENSG00000112715> .

<http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/id58af8d42>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP5216_r126981> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP5216_r126981/Interaction/id58af8d42> ;
        wp:participants   <https://identifiers.org/ncbigene/3939> , <https://identifiers.org/ncbigene/57695> ;
        wp:source         <https://identifiers.org/ncbigene/57695> ;
        wp:target         <https://identifiers.org/ncbigene/3939> .

<http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/id49634da>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP5216_r126981> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP5216_r126981/Interaction/id49634da> ;
        wp:participants   <https://identifiers.org/chebi/CHEBI:61527> , <https://identifiers.org/chebi/CHEBI:4170> ;
        wp:source         <https://identifiers.org/chebi/CHEBI:4170> ;
        wp:target         <https://identifiers.org/chebi/CHEBI:61527> .

<http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/iddc7d8937>
        rdf:type          wp:Catalysis , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP5216_r126981> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP5216_r126981/Interaction/iddc7d8937> ;
        wp:participants   <https://identifiers.org/ncbigene/2538> , <http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/id431f798b> ;
        wp:source         <https://identifiers.org/ncbigene/2538> ;
        wp:target         <http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/id431f798b> .

<https://identifiers.org/hgnc.symbol/FBP1>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "FBP1" ;
        dc:identifier       <https://identifiers.org/hgnc.symbol/FBP1> ;
        dc:source           "HGNC" ;
        dcterms:identifier  "FBP1" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/idc8d05b6f> , <https://identifiers.org/wikipathways/WP5216_r126981> , <http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/idfdbe3a7f> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000165140> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/2203> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/FBP1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/P09467> , <https://identifiers.org/uniprot/Q5VZC3> , <https://identifiers.org/uniprot/A0A804HJK9> , <https://identifiers.org/uniprot/A0A3B3IUC7> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5216_r126981/DataNode/cd6e0> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q5VZC3> , <http://purl.uniprot.org/uniprot/A0A804HJK9> , <http://purl.uniprot.org/uniprot/P09467> , <http://purl.uniprot.org/uniprot/A0A3B3IUC7> ;
        foaf:page           <https://www.genenames.org/data/gene-symbol-report/#!/symbol/FBP1> .

obo:NCBITaxon_9606  obo:NCIT_C179773  "9606" .

<http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/id4a21908d>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP5216_r126981> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP5216_r126981/Interaction/id4a21908d> ;
        wp:participants   <https://identifiers.org/ncbigene/2308> , <https://identifiers.org/ncbigene/7874> ;
        wp:source         <https://identifiers.org/ncbigene/7874> ;
        wp:target         <https://identifiers.org/ncbigene/2308> .

<http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/id63384f0d>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP5216_r126981> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP5216_r126981/Interaction/id63384f0d> ;
        wp:participants   <https://identifiers.org/chebi/CHEBI:4170> , <https://identifiers.org/chebi/CHEBI:4167> ;
        wp:source         <https://identifiers.org/chebi/CHEBI:4167> ;
        wp:target         <https://identifiers.org/chebi/CHEBI:4170> .

<https://identifiers.org/ncbigene/2475>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "MTOR" ;
        dc:identifier       <https://identifiers.org/ncbigene/2475> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "2475" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/id92d66332> , <https://identifiers.org/wikipathways/WP5216_r126981> , <http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/iddaf4e1c6> , <http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/idfd935ea5> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000198793> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/2475> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/MTOR> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A8V8TR74> , <https://identifiers.org/uniprot/A0A8V8TQM6> , <https://identifiers.org/uniprot/A0A8V8TRG9> , <https://identifiers.org/uniprot/A0A8V8TQN3> , <https://identifiers.org/uniprot/A0A8V8TQ52> , <https://identifiers.org/uniprot/P42345> , <https://identifiers.org/uniprot/A0A8V8TQP2> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5216_r126981/DataNode/d9551> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A8V8TQM6> , <http://purl.uniprot.org/uniprot/A0A8V8TQ52> , <http://purl.uniprot.org/uniprot/A0A8V8TQN3> , <http://purl.uniprot.org/uniprot/A0A8V8TR74> , <http://purl.uniprot.org/uniprot/A0A8V8TRG9> , <http://purl.uniprot.org/uniprot/A0A8V8TQP2> , <http://purl.uniprot.org/uniprot/P42345> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/2475> .

<https://identifiers.org/ncbigene/84101>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "USP44" ;
        dc:identifier       <https://identifiers.org/ncbigene/84101> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "84101" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP5216_r126981> , <http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/idfdbe3a7f> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000136014> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/84101> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/USP44> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/F8VRW0> , <https://identifiers.org/uniprot/F8VVD6> , <https://identifiers.org/uniprot/Q9H0E7> , <https://identifiers.org/uniprot/A0A024RBD7> , <https://identifiers.org/uniprot/F8VRI7> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5216_r126981/DataNode/d6017> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/F8VVD6> , <http://purl.uniprot.org/uniprot/F8VRW0> , <http://purl.uniprot.org/uniprot/Q9H0E7> , <http://purl.uniprot.org/uniprot/F8VRI7> , <http://purl.uniprot.org/uniprot/A0A024RBD7> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/84101> .

<http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/idfd935ea5>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP5216_r126981> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP5216_r126981/Interaction/idfd935ea5> ;
        wp:participants   <https://identifiers.org/ncbigene/2475> , <https://identifiers.org/ncbigene/78990> ;
        wp:source         <https://identifiers.org/ncbigene/78990> ;
        wp:target         <https://identifiers.org/ncbigene/2475> .

<https://identifiers.org/ncbigene/10869>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "USP19" ;
        dc:identifier       <https://identifiers.org/ncbigene/10869> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "10869" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP5216_r126981> , <http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/id42ad3a5d> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000172046> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/10869> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/USP19> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A8I5KRW4> , <https://identifiers.org/uniprot/A0A8I5KXK1> , <https://identifiers.org/uniprot/A0A0A0MR08> , <https://identifiers.org/uniprot/O94966> , <https://identifiers.org/uniprot/A0A8V8TN96> , <https://identifiers.org/uniprot/E7ESU0> , <https://identifiers.org/uniprot/A0A8I5KV50> , <https://identifiers.org/uniprot/A0A8I5KT08> , <https://identifiers.org/uniprot/A0A590UK03> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5216_r126981/DataNode/e3dd2> , <http://rdf.wikipathways.org/Pathway/WP5216_r126981/DataNode/f5e42> , <http://rdf.wikipathways.org/Pathway/WP5216_r126981/DataNode/bd933> , <http://rdf.wikipathways.org/Pathway/WP5216_r126981/DataNode/affd3> , <http://rdf.wikipathways.org/Pathway/WP5216_r126981/DataNode/e07a8> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A8I5KXK1> , <http://purl.uniprot.org/uniprot/A0A590UK03> , <http://purl.uniprot.org/uniprot/A0A8V8TN96> , <http://purl.uniprot.org/uniprot/A0A0A0MR08> , <http://purl.uniprot.org/uniprot/A0A8I5KV50> , <http://purl.uniprot.org/uniprot/O94966> , <http://purl.uniprot.org/uniprot/E7ESU0> , <http://purl.uniprot.org/uniprot/A0A8I5KRW4> , <http://purl.uniprot.org/uniprot/A0A8I5KT08> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/10869> .

<https://identifiers.org/chebi/CHEBI:17138>
        rdf:type            wp:DataNode , wp:Metabolite ;
        rdfs:label          "GA3P" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/LXJXRIRHZLFYRP-UHFFFAOYSA-N> ;
        dc:identifier       <https://identifiers.org/chebi/CHEBI:17138> ;
        dc:source           "ChEBI" ;
        dcterms:identifier  "17138" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/idb573a17b> , <https://identifiers.org/wikipathways/WP5216_r126981> , <http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/ide94d83f9> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:17138> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/709> ;
        wp:bdbHmdb          <https://identifiers.org/hmdb/HMDB0001112> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/LXJXRIRHZLFYRP-UHFFFAOYSA-N> ;
        wp:bdbKeggCompound  <https://identifiers.org/kegg.compound/C00661> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID729> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q794810> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5216_r126981/DataNode/aaf68> ;
        foaf:page           <https://www.ebi.ac.uk/chebi/searchId.do?chebiId=17138> .

<http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/idfe89f049>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP5216_r126981> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP5216_r126981/Interaction/idfe89f049> ;
        wp:participants   <https://identifiers.org/ncbigene/2308> , <https://identifiers.org/ncbigene/7874> ;
        wp:source         <https://identifiers.org/ncbigene/7874> ;
        wp:target         <https://identifiers.org/ncbigene/2308> .

<https://identifiers.org/chebi/CHEBI:15361>
        rdf:type            wp:DataNode , wp:Metabolite ;
        rdfs:label          "Pyruvate" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/LCTONWCANYUPML-UHFFFAOYSA-N> ;
        dc:identifier       <https://identifiers.org/chebi/CHEBI:15361> ;
        dc:source           "ChEBI" ;
        dcterms:identifier  "15361" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/idfab8b1f7> , <http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/idf26117c4> , <http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/id90f1ae6d> , <https://identifiers.org/wikipathways/WP5216_r126981> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:15361> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/96901> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/LCTONWCANYUPML-UHFFFAOYSA-M> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID107735> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q27089397> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5216_r126981/DataNode/da690> , <http://rdf.wikipathways.org/Pathway/WP5216_r126981/DataNode/e5139> ;
        owl:sameAs          <https://swisslipids.org/rdf/SLM_000000404> ;
        foaf:page           <https://www.ebi.ac.uk/chebi/searchId.do?chebiId=15361> .

<http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/idfab8b1f7>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP5216_r126981> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP5216_r126981/Interaction/idfab8b1f7> ;
        wp:participants   <https://identifiers.org/chebi/CHEBI:15361> , <https://identifiers.org/chebi/CHEBI:18021> ;
        wp:source         <https://identifiers.org/chebi/CHEBI:18021> ;
        wp:target         <https://identifiers.org/chebi/CHEBI:15361> .

<http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/idf26117c4>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP5216_r126981> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP5216_r126981/Interaction/idf26117c4> ;
        wp:participants   <https://identifiers.org/chebi/CHEBI:15361> , <https://identifiers.org/chebi/CHEBI:18021> ;
        wp:source         <https://identifiers.org/chebi/CHEBI:18021> ;
        wp:target         <https://identifiers.org/chebi/CHEBI:15361> .

<http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/id6fdf5fd4>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP5216_r126981> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP5216_r126981/Interaction/id6fdf5fd4> ;
        wp:participants   <https://identifiers.org/ncbigene/5230> , <https://identifiers.org/ncbigene/78990> ;
        wp:source         <https://identifiers.org/ncbigene/78990> ;
        wp:target         <https://identifiers.org/ncbigene/5230> .

<https://identifiers.org/chebi/CHEBI:61527>
        rdf:type            wp:Metabolite , wp:DataNode ;
        rdfs:label          "F6P" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/BGWGXPAPYGQALX-VRPWFDPXSA-N> ;
        dc:identifier       <https://identifiers.org/chebi/CHEBI:61527> ;
        dc:source           "ChEBI" ;
        dcterms:identifier  "61527" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/id356e003f> , <http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/id823acbbd> , <https://identifiers.org/wikipathways/WP5216_r126981> , <http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/id49634da> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:61527> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/10463779> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/BGWGXPAPYGQALX-VRPWFDPXSA-L> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID23421195> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q27131127> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5216_r126981/DataNode/b914e> ;
        foaf:page           <https://www.ebi.ac.uk/chebi/searchId.do?chebiId=61527> .

<http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/iddaf4e1c6>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP5216_r126981> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP5216_r126981/Interaction/iddaf4e1c6> ;
        wp:participants   <https://identifiers.org/ncbigene/3091> , <https://identifiers.org/ncbigene/2475> ;
        wp:source         <https://identifiers.org/ncbigene/2475> ;
        wp:target         <https://identifiers.org/ncbigene/3091> .

<http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/idd414123e>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP5216_r126981> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP5216_r126981/Interaction/idd414123e> ;
        wp:participants   <https://identifiers.org/ncbigene/207> , <https://identifiers.org/ensembl/ENSG00000121879> ;
        wp:source         <https://identifiers.org/ensembl/ENSG00000121879> ;
        wp:target         <https://identifiers.org/ncbigene/207> .

<http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/id145f76be>
        rdf:type          wp:TranscriptionTranslation , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP5216_r126981> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP5216_r126981/Interaction/id145f76be> ;
        wp:participants   <https://identifiers.org/ncbigene/3939> , <https://identifiers.org/ensembl/ENSG00000136997> ;
        wp:source         <https://identifiers.org/ensembl/ENSG00000136997> ;
        wp:target         <https://identifiers.org/ncbigene/3939> .

<http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/iddeaa8afe>
        rdf:type          wp:Catalysis , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP5216_r126981> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP5216_r126981/Interaction/iddeaa8afe> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000159399> , <http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/id63384f0d> ;
        wp:source         <https://identifiers.org/ensembl/ENSG00000159399> ;
        wp:target         <http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/id63384f0d> .

<https://identifiers.org/ensembl/ENSG00000112715>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "VEGF" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000112715> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000112715" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/idac528ce> , <http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/id42ad3a5d> , <https://identifiers.org/wikipathways/WP5216_r126981> ;
        dcterms:references  <https://identifiers.org/pubmed/23216836> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000112715> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/7422> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/VEGFA> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/H0YBI8> , <https://identifiers.org/uniprot/A0A0A0MSH5> , <https://identifiers.org/uniprot/J3KPA4> , <https://identifiers.org/uniprot/A0A0A0MTB2> , <https://identifiers.org/uniprot/A0A0Y0IMM4> , <https://identifiers.org/uniprot/H3BLW8> , <https://identifiers.org/uniprot/A0A0A0MR43> , <https://identifiers.org/uniprot/P15692> , <https://identifiers.org/uniprot/A2A2V4> , <https://identifiers.org/uniprot/A0A024RD33> , <https://identifiers.org/uniprot/A0A5F9ZH41> , <https://identifiers.org/uniprot/A0A0A0MSI7> , <https://identifiers.org/uniprot/A0A024RD37> , <https://identifiers.org/uniprot/H0YBZ0> , <https://identifiers.org/uniprot/A0A0A0MSH7> , <https://identifiers.org/uniprot/A0A0A0MRQ4> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18032324> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5216_r126981/DataNode/f9fb4> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/J3KPA4> , <http://purl.uniprot.org/uniprot/A0A024RD33> , <http://purl.uniprot.org/uniprot/H3BLW8> , <http://purl.uniprot.org/uniprot/A0A5F9ZH41> , <http://purl.uniprot.org/uniprot/A0A0A0MTB2> , <http://purl.uniprot.org/uniprot/H0YBZ0> , <http://purl.uniprot.org/uniprot/A0A0A0MSH5> , <http://purl.uniprot.org/uniprot/A2A2V4> , <http://purl.uniprot.org/uniprot/A0A0A0MRQ4> , <http://purl.uniprot.org/uniprot/A0A0A0MR43> , <http://purl.uniprot.org/uniprot/A0A0A0MSI7> , <http://purl.uniprot.org/uniprot/A0A0A0MSH7> , <http://purl.uniprot.org/uniprot/P15692> , <http://purl.uniprot.org/uniprot/A0A0Y0IMM4> , <http://purl.uniprot.org/uniprot/A0A024RD37> , <http://purl.uniprot.org/uniprot/H0YBI8> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000112715> .

<http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/ideaa5b55b>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP5216_r126981> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP5216_r126981/Interaction/ideaa5b55b> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000117394> , <https://identifiers.org/ncbigene/3091> ;
        wp:source         <https://identifiers.org/ncbigene/3091> ;
        wp:target         <https://identifiers.org/ensembl/ENSG00000117394> .

<http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/id823acbbd>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP5216_r126981> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP5216_r126981/Interaction/id823acbbd> ;
        wp:participants   <https://identifiers.org/chebi/CHEBI:61527> , <https://identifiers.org/chebi/CHEBI:32966> ;
        wp:source         <https://identifiers.org/chebi/CHEBI:32966> ;
        wp:target         <https://identifiers.org/chebi/CHEBI:61527> .

<http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/idfdbe3a7f>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP5216_r126981> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP5216_r126981/Interaction/idfdbe3a7f> ;
        wp:participants   <https://identifiers.org/hgnc.symbol/FBP1> , <https://identifiers.org/ncbigene/84101> ;
        wp:source         <https://identifiers.org/ncbigene/84101> ;
        wp:target         <https://identifiers.org/hgnc.symbol/FBP1> .

<https://identifiers.org/wikipathways/WP5216_r126981>
        rdf:type               skos:Collection , wp:Pathway ;
        dc:identifier          <https://identifiers.org/wikipathways/WP5216> ;
        dc:source              "WikiPathways" ;
        dc:title               "Warburg effect modulated by deubiquitinating enzymes and their substrates"@en ;
        dcterms:description    "Even in the presence of oxygen, cancer cells convert glucose to lactate as their main source for energy production, instead of using the citric acid cycle and oxidative phosphorylation. This process is called the Warburg effect. This pathway shows the effects deubiquitinating enzymes (DUBs) and their substrates have. DUBs free proteins of their ubiquitin chain, so that the proteins can resume their function in the cells rather than be degraded by the ubiquitin-proteasome system (UPS). \nThe deubiquitination of VHL via OTUD6B (part of a DUB subfamily) represses HIF-1α, whereas the direct deubiquitination of HIF-1a via DUBs leads to the increased expression of GLUT1 and VEGF. The transcription factor c-Myc helps regulate gene expression involved in the glucose metabolism (e.g., GLUT1, HK2, LDHA) and is stabilised by ubiquitin-specific proteases.  The PI3K/Akt pathway is also upregulated by deubiquitination of VEGF and Akt. This entails cell growth and apoptosis regulation, as well as promoted glucose transport to cancer cells and activating mTor, which improves glycolysis.\nIt is shown in this pathway, how deubiquitinating enzymes play an important role in stabilizing different proteins, acting as oncoproteins and tumor suppressors equally.\nThis pathway is based on figure 3 featured in “Regulation of Cancer Metabolism by Deubiquitinating Enzymes: The Warburg Effect” by So-Hee Kim and Kwang-Hyun Baek." ;
        dcterms:identifier     "WP5216" ;
        dcterms:references     <https://doi.org/10.3390/IJMS22126173> ;
        cito:cites             <https://doi.org/10.3390/IJMS22126173> , <https://identifiers.org/pubmed/21591214> , <https://identifiers.org/pubmed/23216836> , <https://identifiers.org/pubmed/30742905> ;
        wp:diseaseOntologyTag  obo:DOID_162 ;
        wp:isAbout             <http://rdf.wikipathways.org/Pathway/WP5216_r126981> ;
        wp:ontologyTag         obo:PW_0000640 , wp:Curation:AnalysisCollection , wp:Curation:ONTOX , wp:Curation:CPTAC , obo:DOID_162 ;
        wp:organism            obo:NCBITaxon_9606 ;
        wp:organismName        "Homo sapiens" ;
        wp:pathwayOntologyTag  obo:PW_0000640 ;
        foaf:img               <https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=svg&pwTitle=Pathway:WP5216&oldid=126981> , <https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=png&pwTitle=Pathway:WP5216&oldid=126981> ;
        foaf:page              <http://www.wikipathways.org/instance/WP5216_r126981> .

<https://identifiers.org/pubmed/21591214>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "21591214" ;
        dcterms:isPartOf    <https://identifiers.org/chebi/CHEBI:18021> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/21591214> .

<http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/idd19bc614>
        rdf:type          wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP5216_r126981> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP5216_r126981/Interaction/idd19bc614> .

<http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/id91684b77>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP5216_r126981> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP5216_r126981/Interaction/id91684b77> ;
        wp:participants   <https://identifiers.org/chebi/CHEBI:17050> , <https://identifiers.org/chebi/CHEBI:89363> ;
        wp:source         <https://identifiers.org/chebi/CHEBI:89363> ;
        wp:target         <https://identifiers.org/chebi/CHEBI:17050> .

<https://identifiers.org/chebi/CHEBI:32966>
        rdf:type            wp:DataNode , wp:Metabolite ;
        rdfs:label          "F1,6BP" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/RNBGYGVWRKECFJ-ARQDHWQXSA-N> ;
        dc:identifier       <https://identifiers.org/chebi/CHEBI:32966> ;
        dc:source           "ChEBI" ;
        dcterms:identifier  "32966" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP5216_r126981> , <http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/ide94d83f9> , <http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/id823acbbd> , <http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/id356e003f> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:32966> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/4574223> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/RNBGYGVWRKECFJ-ARQDHWQXSA-J> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID5460765> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q27115161> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5216_r126981/DataNode/a6169> ;
        foaf:page           <https://www.ebi.ac.uk/chebi/searchId.do?chebiId=32966> .

<https://identifiers.org/ncbigene/56957>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "OTUD7B" ;
        dc:identifier       <https://identifiers.org/ncbigene/56957> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "56957" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP5216_r126981> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000264522> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/56957> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/OTUD7B> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q5SZ59> , <https://identifiers.org/uniprot/Q6GQQ9> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5216_r126981/DataNode/c6742> , <http://rdf.wikipathways.org/Pathway/WP5216_r126981/DataNode/d6d58> , <http://rdf.wikipathways.org/Pathway/WP5216_r126981/DataNode/ca6c7> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q6GQQ9> , <http://purl.uniprot.org/uniprot/Q5SZ59> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/56957> .

<http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/id92d66332>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP5216_r126981> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP5216_r126981/Interaction/id92d66332> ;
        wp:participants   <https://identifiers.org/ncbigene/2475> , <https://identifiers.org/ncbigene/207> ;
        wp:source         <https://identifiers.org/ncbigene/207> ;
        wp:target         <https://identifiers.org/ncbigene/2475> .

<https://doi.org/10.3390/IJMS22126173>
        rdf:type          wp:PublicationReference ;
        dc:source         "DOI" ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP5216_r126981> ;
        foaf:page         <https://doi.org/10.3390/IJMS22126173> .

<http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/idac528ce>
        rdf:type          wp:Binding , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP5216_r126981> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP5216_r126981/Interaction/idac528ce> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000128052> , <https://identifiers.org/ensembl/ENSG00000112715> ;
        wp:source         <https://identifiers.org/ensembl/ENSG00000112715> ;
        wp:target         <https://identifiers.org/ensembl/ENSG00000128052> .

<https://identifiers.org/ensembl/ENSG00000159399>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "HK2" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000159399> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000159399" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/id7d485c38> , <https://identifiers.org/wikipathways/WP5216_r126981> , <http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/ide5cafcd2> , <http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/iddeaa8afe> , <http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/idf42cce1f> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000159399> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/3099> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/HK2> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/E9PB90> , <https://identifiers.org/uniprot/P52789> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18026912> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5216_r126981/DataNode/b2052> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/E9PB90> , <http://purl.uniprot.org/uniprot/P52789> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000159399> .

<https://identifiers.org/ncbigene/2538>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "G6PC" ;
        dc:identifier       <https://identifiers.org/ncbigene/2538> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "2538" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/id4c738f7e> , <https://identifiers.org/wikipathways/WP5216_r126981> , <http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/id581f8ac9> , <http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/iddc7d8937> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000131482> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/2538> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/G6PC1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/P35575> , <https://identifiers.org/uniprot/K7ELS6> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5216_r126981/DataNode/e91bf> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P35575> , <http://purl.uniprot.org/uniprot/K7ELS6> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/2538> .

<https://identifiers.org/pubmed/30742905>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "30742905" ;
        dcterms:isPartOf    <https://identifiers.org/ensembl/ENSG00000121879> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/30742905> .

<http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/idd62e7732>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP5216_r126981> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP5216_r126981/Interaction/idd62e7732> ;
        wp:participants   <https://identifiers.org/ncbigene/207> , <https://identifiers.org/ncbigene/78990> ;
        wp:source         <https://identifiers.org/ncbigene/78990> ;
        wp:target         <https://identifiers.org/ncbigene/207> .

<http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/id8ec4ad54>
        rdf:type          wp:Inhibition , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP5216_r126981> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP5216_r126981/Interaction/id8ec4ad54> ;
        wp:participants   <https://identifiers.org/ncbigene/3091> , <https://identifiers.org/ensembl/ENSG00000134086> ;
        wp:source         <https://identifiers.org/ensembl/ENSG00000134086> ;
        wp:target         <https://identifiers.org/ncbigene/3091> .

<http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/id478f171b>
        rdf:type          wp:Inhibition , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP5216_r126981> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP5216_r126981/Interaction/id478f171b> ;
        wp:participants   <https://identifiers.org/ncbigene/5230> , <https://identifiers.org/ncbigene/11338> ;
        wp:source         <https://identifiers.org/ncbigene/11338> ;
        wp:target         <https://identifiers.org/ncbigene/5230> .

<https://doi.org/10.1111%2FJOIM.12019>
        dc:source           "DOI" ;
        dcterms:identifier  "10.1111/JOIM.12019" .

<https://identifiers.org/ensembl/ENSG00000117394>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "GLUT1" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000117394> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000117394" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/idbecdfda> , <http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/id48664eb4> , <https://identifiers.org/wikipathways/WP5216_r126981> , <http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/ideaa5b55b> , <http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/idac23cbf3> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000117394> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/6513> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/SLC2A1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A1W2PQ59> , <https://identifiers.org/uniprot/A6NL68> , <https://identifiers.org/uniprot/A0A0D9SG74> , <https://identifiers.org/uniprot/A0A6Q8PFI8> , <https://identifiers.org/uniprot/A0A0D9SFK9> , <https://identifiers.org/uniprot/P11166> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q14904883> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5216_r126981/DataNode/c7846> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A0D9SG74> , <http://purl.uniprot.org/uniprot/A0A1W2PQ59> , <http://purl.uniprot.org/uniprot/A6NL68> , <http://purl.uniprot.org/uniprot/A0A6Q8PFI8> , <http://purl.uniprot.org/uniprot/A0A0D9SFK9> , <http://purl.uniprot.org/uniprot/P11166> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000117394> .

<http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/ide8a854e>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP5216_r126981> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP5216_r126981/Interaction/ide8a854e> ;
        wp:participants   <https://identifiers.org/ncbigene/11338> , <https://identifiers.org/ncbigene/78990> ;
        wp:source         <https://identifiers.org/ncbigene/78990> ;
        wp:target         <https://identifiers.org/ncbigene/11338> .

<https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=png&pwTitle=Pathway:WP5216&oldid=126981>
        rdf:type        foaf:Image ;
        dcterms:format  "image/png" .

<http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/id61e01cb3>
        rdf:type          wp:Catalysis , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP5216_r126981> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP5216_r126981/Interaction/id61e01cb3> ;
        wp:participants   <https://identifiers.org/ncbigene/51547> , <http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/id91c5a538> ;
        wp:source         <https://identifiers.org/ncbigene/51547> ;
        wp:target         <http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/id91c5a538> .

<https://identifiers.org/ncbigene/78990>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "OTUB2" ;
        dc:identifier       <https://identifiers.org/ncbigene/78990> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "78990" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/id25d9d322> , <http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/idd62e7732> , <http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/ide5cafcd2> , <http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/idfd935ea5> , <http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/id6fdf5fd4> , <http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/ide8a854e> , <https://identifiers.org/wikipathways/WP5216_r126981> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000089723> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/78990> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/OTUB2> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q96DC9> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5216_r126981/DataNode/eaf14> , <http://rdf.wikipathways.org/Pathway/WP5216_r126981/DataNode/de9b9> , <http://rdf.wikipathways.org/Pathway/WP5216_r126981/DataNode/c3af9> , <http://rdf.wikipathways.org/Pathway/WP5216_r126981/DataNode/d4259> , <http://rdf.wikipathways.org/Pathway/WP5216_r126981/DataNode/e8056> , <http://rdf.wikipathways.org/Pathway/WP5216_r126981/DataNode/a2f58> , <http://rdf.wikipathways.org/Pathway/WP5216_r126981/DataNode/e09b6> , <http://rdf.wikipathways.org/Pathway/WP5216_r126981/DataNode/edd70> , <http://rdf.wikipathways.org/Pathway/WP5216_r126981/DataNode/f0ca3> , <http://rdf.wikipathways.org/Pathway/WP5216_r126981/DataNode/c0e26> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q96DC9> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/78990> .

<http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/id48664eb4>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP5216_r126981> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP5216_r126981/Interaction/id48664eb4> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000117394> , <https://identifiers.org/ncbigene/207> ;
        wp:source         <https://identifiers.org/ncbigene/207> ;
        wp:target         <https://identifiers.org/ensembl/ENSG00000117394> .

<http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/id4394d9f8>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP5216_r126981> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP5216_r126981/Interaction/id4394d9f8> ;
        wp:participants   <https://identifiers.org/ncbigene/51547> , <https://identifiers.org/ncbigene/7874> ;
        wp:source         <https://identifiers.org/ncbigene/7874> ;
        wp:target         <https://identifiers.org/ncbigene/51547> .

<https://identifiers.org/chebi/CHEBI:89363>
        rdf:type            wp:DataNode , wp:Metabolite ;
        rdfs:label          "1,3-BPG" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/LJQLQCAXBUHEAZ-UHFFFAOYSA-N> ;
        dc:identifier       <https://identifiers.org/chebi/CHEBI:89363> ;
        dc:source           "ChEBI" ;
        dcterms:identifier  "89363" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/id91684b77> , <https://identifiers.org/wikipathways/WP5216_r126981> , <http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/idb573a17b> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:89363> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/663> , <https://identifiers.org/chemspider/21230406> ;
        wp:bdbHmdb          <https://identifiers.org/hmdb/HMDB0001270> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/LJQLQCAXBUHEAZ-UHFFFAOYSA-N> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID683> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q1020557> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5216_r126981/DataNode/af493> ;
        foaf:page           <https://www.ebi.ac.uk/chebi/searchId.do?chebiId=89363> .

<http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/id242a7a14>
        rdf:type          wp:TranscriptionTranslation , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP5216_r126981> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP5216_r126981/Interaction/id242a7a14> ;
        wp:participants   <https://identifiers.org/ncbigene/3939> , <https://identifiers.org/ncbigene/3091> ;
        wp:source         <https://identifiers.org/ncbigene/3091> ;
        wp:target         <https://identifiers.org/ncbigene/3939> .

<https://identifiers.org/ncbigene/5223>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "PGAM1" ;
        dc:identifier       <https://identifiers.org/ncbigene/5223> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "5223" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/ide23d1db> , <https://identifiers.org/wikipathways/WP5216_r126981> , <http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/id25d9d322> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000171314> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/5223> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/PGAM1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/P18669> , <https://identifiers.org/uniprot/Q6FHU2> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5216_r126981/DataNode/d59f0> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P18669> , <http://purl.uniprot.org/uniprot/Q6FHU2> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/5223> .

<https://identifiers.org/ncbigene/51547>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "SIRT7" ;
        dc:identifier       <https://identifiers.org/ncbigene/51547> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "51547" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP5216_r126981> , <http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/id61e01cb3> , <http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/id4394d9f8> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000187531> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/51547> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/SIRT7> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/I3L2A4> , <https://identifiers.org/uniprot/Q9NRC8> , <https://identifiers.org/uniprot/I3L480> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5216_r126981/DataNode/a065f> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/I3L480> , <http://purl.uniprot.org/uniprot/I3L2A4> , <http://purl.uniprot.org/uniprot/Q9NRC8> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/51547> .

<http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/idd471abf1>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP5216_r126981> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP5216_r126981/Interaction/idd471abf1> ;
        wp:participants   <https://identifiers.org/chebi/CHEBI:24344> , <https://identifiers.org/chebi/CHEBI:17050> ;
        wp:source         <https://identifiers.org/chebi/CHEBI:17050> ;
        wp:target         <https://identifiers.org/chebi/CHEBI:24344> .

<https://identifiers.org/chebi/CHEBI:24344>
        rdf:type            wp:Metabolite , wp:DataNode ;
        rdfs:label          "2PG" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/GXIURPTVHJPJLF-UHFFFAOYSA-N> ;
        dc:identifier       <https://identifiers.org/chebi/CHEBI:24344> ;
        dc:source           "ChEBI" ;
        dcterms:identifier  "24344" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/id66afe83a> , <http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/idd471abf1> , <https://identifiers.org/wikipathways/WP5216_r126981> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:24344> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/58> ;
        wp:bdbHmdb          <https://identifiers.org/hmdb/HMDB0000362> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/GXIURPTVHJPJLF-UHFFFAOYSA-N> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID59> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q209469> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5216_r126981/DataNode/c5ab2> ;
        foaf:page           <https://www.ebi.ac.uk/chebi/searchId.do?chebiId=24344> .

<http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/idd0b23cb0>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP5216_r126981> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP5216_r126981/Interaction/idd0b23cb0> ;
        wp:participants   <https://identifiers.org/chebi/CHEBI:4167> ;
        wp:source         <https://identifiers.org/chebi/CHEBI:4167> ;
        wp:target         <https://identifiers.org/chebi/CHEBI:4167> .

<https://identifiers.org/chebi/CHEBI:4170>
        rdf:type            wp:Metabolite , wp:DataNode ;
        rdfs:label          "G6P" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/NBSCHQHZLSJFNQ-GASJEMHNSA-N> ;
        dc:identifier       <https://identifiers.org/chebi/CHEBI:4170> ;
        dc:source           "ChEBI" ;
        dcterms:identifier  "4170" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP5216_r126981> , <http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/id431f798b> , <http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/id49634da> , <http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/id63384f0d> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:4170> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/5743> , <https://identifiers.org/chemspider/17216117> ;
        wp:bdbHmdb          <https://identifiers.org/hmdb/HMDB0001401> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/NBSCHQHZLSJFNQ-GASJEMHNSA-N> ;
        wp:bdbKeggCompound  <https://identifiers.org/kegg.compound/C00092> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID5958> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q36461529> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5216_r126981/DataNode/f7387> ;
        foaf:page           <https://www.ebi.ac.uk/chebi/searchId.do?chebiId=4170> .

<https://identifiers.org/ncbigene/5230>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "PGK1" ;
        dc:identifier       <https://identifiers.org/ncbigene/5230> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "5230" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/id91c5a538> , <http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/id6fdf5fd4> , <http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/id478f171b> , <https://identifiers.org/wikipathways/WP5216_r126981> , <http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/id4137c26f> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000102144> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/5230> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/PGK1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/P00558> , <https://identifiers.org/uniprot/V9HWF4> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5216_r126981/DataNode/c3f11> , <http://rdf.wikipathways.org/Pathway/WP5216_r126981/DataNode/adb59> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/V9HWF4> , <http://purl.uniprot.org/uniprot/P00558> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/5230> .

<http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/id91c5a538>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP5216_r126981> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP5216_r126981/Interaction/id91c5a538> ;
        wp:participants   <https://identifiers.org/ncbigene/5230> ;
        wp:source         <https://identifiers.org/ncbigene/5230> ;
        wp:target         <https://identifiers.org/ncbigene/5230> .

<https://identifiers.org/ncbigene/7874>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "USP7" ;
        dc:identifier       <https://identifiers.org/ncbigene/7874> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "7874" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/idfe89f049> , <https://identifiers.org/wikipathways/WP5216_r126981> , <http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/id4c738f7e> , <http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/id4394d9f8> , <http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/id4a21908d> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000187555> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/7874> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/USP7> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/H3BND8> , <https://identifiers.org/uniprot/H3BQD1> , <https://identifiers.org/uniprot/H3BMF6> , <https://identifiers.org/uniprot/H3BUV0> , <https://identifiers.org/uniprot/Q93009> , <https://identifiers.org/uniprot/I3L2D8> , <https://identifiers.org/uniprot/A0A669KBL1> , <https://identifiers.org/uniprot/H3BRI4> , <https://identifiers.org/uniprot/F5H2X1> , <https://identifiers.org/uniprot/H3BTM1> , <https://identifiers.org/uniprot/H3BVA7> , <https://identifiers.org/uniprot/H3BRA2> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5216_r126981/DataNode/efdf6> , <http://rdf.wikipathways.org/Pathway/WP5216_r126981/DataNode/bdc4f> , <http://rdf.wikipathways.org/Pathway/WP5216_r126981/DataNode/f7737> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/H3BVA7> , <http://purl.uniprot.org/uniprot/H3BTM1> , <http://purl.uniprot.org/uniprot/F5H2X1> , <http://purl.uniprot.org/uniprot/H3BMF6> , <http://purl.uniprot.org/uniprot/H3BUV0> , <http://purl.uniprot.org/uniprot/I3L2D8> , <http://purl.uniprot.org/uniprot/H3BND8> , <http://purl.uniprot.org/uniprot/H3BQD1> , <http://purl.uniprot.org/uniprot/H3BRI4> , <http://purl.uniprot.org/uniprot/H3BRA2> , <http://purl.uniprot.org/uniprot/A0A669KBL1> , <http://purl.uniprot.org/uniprot/Q93009> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/7874> .

<https://identifiers.org/ncbigene/51633>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "OTUD6B" ;
        dc:identifier       <https://identifiers.org/ncbigene/51633> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "51633" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/id80aeae06> , <https://identifiers.org/wikipathways/WP5216_r126981> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000155100> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/51633> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/OTUD6B> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A0C4DH76> , <https://identifiers.org/uniprot/A0A087X0W9> , <https://identifiers.org/uniprot/Q8N6M0> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5216_r126981/DataNode/c01b6> , <http://rdf.wikipathways.org/Pathway/WP5216_r126981/DataNode/df580> , <http://rdf.wikipathways.org/Pathway/WP5216_r126981/DataNode/d5591> , <http://rdf.wikipathways.org/Pathway/WP5216_r126981/DataNode/c1c1b> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A0C4DH76> , <http://purl.uniprot.org/uniprot/A0A087X0W9> , <http://purl.uniprot.org/uniprot/Q8N6M0> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/51633> .

<http://rdf.wikipathways.org/Pathway/WP5216_r126981/WP/Interaction/id7d485c38>
        rdf:type          wp:TranscriptionTranslation , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP5216_r126981> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP5216_r126981/Interaction/id7d485c38> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000159399> , <https://identifiers.org/ensembl/ENSG00000136997> ;
        wp:source         <https://identifiers.org/ensembl/ENSG00000136997> ;
        wp:target         <https://identifiers.org/ensembl/ENSG00000159399> .
