@prefix biopax:  <http://www.biopax.org/release/biopax-level3.owl#> .
@prefix cito:    <http://purl.org/spar/cito/> .
@prefix dc:      <http://purl.org/dc/elements/1.1/> .
@prefix dcterms: <http://purl.org/dc/terms/> .
@prefix foaf:    <http://xmlns.com/foaf/0.1/> .
@prefix freq:    <http://purl.org/cld/freq/> .
@prefix gpml:    <http://vocabularies.wikipathways.org/gpml#> .
@prefix obo:     <http://purl.obolibrary.org/obo/> .
@prefix owl:     <http://www.w3.org/2002/07/owl#> .
@prefix pav:     <http://purl.org/pav/> .
@prefix prov:    <http://www.w3.org/ns/prov#> .
@prefix rdf:     <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix rdfs:    <http://www.w3.org/2000/01/rdf-schema#> .
@prefix skos:    <http://www.w3.org/2004/02/skos/core#> .
@prefix void:    <http://rdfs.org/ns/void#> .
@prefix wp:      <http://vocabularies.wikipathways.org/wp#> .
@prefix wprdf:   <http://rdf.wikipathways.org/> .
@prefix xsd:     <http://www.w3.org/2001/XMLSchema#> .

<https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=png&pwTitle=Pathway:WP517&oldid=116994>
        rdf:type        foaf:Image ;
        dcterms:format  "image/png" .

<https://identifiers.org/ensembl/ENSRNOG00000005129>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "RGD1566181_predicted" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSRNOG00000005129> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSRNOG00000005129" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP517_r116994> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSRNOG00000005129> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A0G2JYQ5> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q24392937> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP517_r116994/DataNode/b27> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A0G2JYQ5> ;
        foaf:page           <https://www.ensembl.org/id/ENSRNOG00000005129> .

<https://identifiers.org/ensembl/ENSRNOG00000013850>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "Hes5" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSRNOG00000013850> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSRNOG00000013850" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP517_r116994> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSRNOG00000013850> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/79225> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q03062> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q24383167> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP517_r116994/DataNode/f06> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q03062> ;
        foaf:page           <https://www.ensembl.org/id/ENSRNOG00000013850> .

<https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=svg&pwTitle=Pathway:WP517&oldid=116994>
        rdf:type        foaf:Image ;
        dcterms:format  "image/svg+xml" .

<https://identifiers.org/ncbigene/116462>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "PTCRA" ;
        dc:identifier       <https://identifiers.org/ncbigene/116462> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "116462" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP517_r116994> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/116462> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP517_r116994/DataNode/c78> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/116462> .

<http://rdf.wikipathways.org/Pathway/WP517_r116994/WP/Interaction/d887b>
        rdf:type          wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP517_r116994> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP517_r116994/Interaction/d887b> ;
        wp:participants   <https://identifiers.org/ensembl/ENSRNOG00000004041> .

<https://identifiers.org/ensembl/ENSRNOG00000005330>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "Crebbp" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSRNOG00000005330> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSRNOG00000005330" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP517_r116994> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSRNOG00000005330> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/54244> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A8I5ZRH6> , <https://identifiers.org/uniprot/F1M9G7> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q24422884> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP517_r116994/DataNode/ccb> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/F1M9G7> , <http://purl.uniprot.org/uniprot/A0A8I5ZRH6> ;
        foaf:page           <https://www.ensembl.org/id/ENSRNOG00000005330> .

<https://identifiers.org/ensembl/ENSRNOG00000005428>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "Ctbp1" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSRNOG00000005428> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSRNOG00000005428" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP517_r116994> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSRNOG00000005428> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/29382> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q9Z2F5> , <https://identifiers.org/uniprot/F7FG31> , <https://identifiers.org/uniprot/A0A0H2UI20> , <https://identifiers.org/uniprot/A0A8I5ZSG1> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q24370019> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP517_r116994/DataNode/eb8> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/F7FG31> , <http://purl.uniprot.org/uniprot/Q9Z2F5> , <http://purl.uniprot.org/uniprot/A0A8I5ZSG1> , <http://purl.uniprot.org/uniprot/A0A0H2UI20> ;
        foaf:page           <https://www.ensembl.org/id/ENSRNOG00000005428> .

<https://identifiers.org/ensembl/ENSRNOG00000009653>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "Q2LC87_RAT" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSRNOG00000009653> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSRNOG00000009653" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP517_r116994> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSRNOG00000009653> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/29419> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q2LC87> , <https://identifiers.org/uniprot/H9KVE4> , <https://identifiers.org/uniprot/Q2LC85> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q24372940> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP517_r116994/DataNode/be2> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q2LC87> , <http://purl.uniprot.org/uniprot/H9KVE4> , <http://purl.uniprot.org/uniprot/Q2LC85> ;
        foaf:page           <https://www.ensembl.org/id/ENSRNOG00000009653> .

<https://identifiers.org/ensembl/ENSRNOG00000013927>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "Jag2" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSRNOG00000013927> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSRNOG00000013927" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP517_r116994> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSRNOG00000013927> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/29147> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/E9PU23> , <https://identifiers.org/uniprot/A0A8I5ZUZ8> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q24369115> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP517_r116994/DataNode/b52> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A8I5ZUZ8> , <http://purl.uniprot.org/uniprot/E9PU23> ;
        foaf:page           <https://www.ensembl.org/id/ENSRNOG00000013927> .

<https://identifiers.org/ensembl/ENSRNOG00000001432>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "LOC688965" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSRNOG00000001432> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSRNOG00000001432" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP517_r116994> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSRNOG00000001432> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/304591> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A8I5ZTQ2> , <https://identifiers.org/uniprot/A0A0G2K039> , <https://identifiers.org/uniprot/G3V658> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q24408693> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP517_r116994/DataNode/bb9> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A0G2K039> , <http://purl.uniprot.org/uniprot/A0A8I5ZTQ2> , <http://purl.uniprot.org/uniprot/G3V658> ;
        foaf:page           <https://www.ensembl.org/id/ENSRNOG00000001432> .

<https://identifiers.org/ensembl/ENSRNOG00000011871>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "Pcaf" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSRNOG00000011871> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSRNOG00000011871" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP517_r116994> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSRNOG00000011871> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A8I5Y222> , <https://identifiers.org/uniprot/A0A8J8YC15> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP517_r116994/DataNode/faa> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A8I5Y222> , <http://purl.uniprot.org/uniprot/A0A8J8YC15> ;
        foaf:page           <https://www.ensembl.org/id/ENSRNOG00000011871> .

<https://identifiers.org/ensembl/ENSRNOG00000021086>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "Dtx4" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSRNOG00000021086> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSRNOG00000021086" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP517_r116994> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSRNOG00000021086> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/293774> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A0G2K048> , <https://identifiers.org/uniprot/A0A8I6A316> , <https://identifiers.org/uniprot/Q6TXG2> , <https://identifiers.org/uniprot/A0A8I6AQV0> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q24422378> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP517_r116994/DataNode/f38> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A0G2K048> , <http://purl.uniprot.org/uniprot/Q6TXG2> , <http://purl.uniprot.org/uniprot/A0A8I6AQV0> , <http://purl.uniprot.org/uniprot/A0A8I6A316> ;
        foaf:page           <https://www.ensembl.org/id/ENSRNOG00000021086> .

<https://identifiers.org/ensembl/ENSRNOG00000000837>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "Tnf" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSRNOG00000000837> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSRNOG00000000837" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP517_r116994> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSRNOG00000000837> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP517_r116994/DataNode/c16> ;
        foaf:page           <https://www.ensembl.org/id/ENSRNOG00000000837> .

<https://identifiers.org/ensembl/ENSRNOG00000038246>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "HDAC2" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSRNOG00000038246> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSRNOG00000038246" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP517_r116994> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSRNOG00000038246> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP517_r116994/DataNode/ff9> ;
        foaf:page           <https://www.ensembl.org/id/ENSRNOG00000038246> .

<https://identifiers.org/pubmed/9245493>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "9245493" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP517_r116994> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/9245493> .

<https://identifiers.org/ensembl/ENSRNOG00000001004>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "NM_001108334.1" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSRNOG00000001004> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSRNOG00000001004" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP517_r116994> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSRNOG00000001004> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/360801> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/D3ZXN9> , <https://identifiers.org/uniprot/A0A8I6AN60> , <https://identifiers.org/uniprot/A0A8I6A620> , <https://identifiers.org/uniprot/A0A8I6GHM0> , <https://identifiers.org/uniprot/A0A0G2JU91> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q24371690> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP517_r116994/DataNode/c13> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A0G2JU91> , <http://purl.uniprot.org/uniprot/A0A8I6A620> , <http://purl.uniprot.org/uniprot/A0A8I6AN60> , <http://purl.uniprot.org/uniprot/A0A8I6GHM0> , <http://purl.uniprot.org/uniprot/D3ZXN9> ;
        foaf:page           <https://www.ensembl.org/id/ENSRNOG00000001004> .

<https://identifiers.org/ensembl/ENSRNOG00000008133>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "Mfng" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSRNOG00000008133> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSRNOG00000008133" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP517_r116994> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSRNOG00000008133> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/G3V725> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q24390523> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP517_r116994/DataNode/f00> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/G3V725> ;
        foaf:page           <https://www.ensembl.org/id/ENSRNOG00000008133> .

<https://identifiers.org/ensembl/ENSRNOG00000005355>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "Ncstn" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSRNOG00000005355> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSRNOG00000005355" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP517_r116994> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSRNOG00000005355> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/289231> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q8CGU6> , <https://identifiers.org/uniprot/B3DM90> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q24408643> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP517_r116994/DataNode/e5b> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q8CGU6> , <http://purl.uniprot.org/uniprot/B3DM90> ;
        foaf:page           <https://www.ensembl.org/id/ENSRNOG00000005355> .

<https://identifiers.org/ensembl/ENSRNOG00000019338>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "Dll3" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSRNOG00000019338> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSRNOG00000019338" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP517_r116994> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSRNOG00000019338> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/114125> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/F1M9P5> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q24370156> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP517_r116994/DataNode/b28> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/F1M9P5> ;
        foaf:page           <https://www.ensembl.org/id/ENSRNOG00000019338> .

<https://identifiers.org/ensembl/ENSRNOG00000026295>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "NP_001102074.1" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSRNOG00000026295> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSRNOG00000026295" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP517_r116994> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSRNOG00000026295> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/362268> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A8I5ZXV0> , <https://identifiers.org/uniprot/D4AEG0> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q24361863> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP517_r116994/DataNode/b01> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/D4AEG0> , <http://purl.uniprot.org/uniprot/A0A8I5ZXV0> ;
        foaf:page           <https://www.ensembl.org/id/ENSRNOG00000026295> .

<https://identifiers.org/ensembl/ENSRNOG00000014667>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "Dll1" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSRNOG00000014667> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSRNOG00000014667" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP517_r116994> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSRNOG00000014667> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP517_r116994/DataNode/dd1> ;
        foaf:page           <https://www.ensembl.org/id/ENSRNOG00000014667> .

<https://identifiers.org/ensembl/ENSRNOG00000001708>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "NP_001100551.1" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSRNOG00000001708> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSRNOG00000001708" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP517_r116994> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSRNOG00000001708> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/303811> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/D4ADV8> , <https://identifiers.org/uniprot/A0A8I6GKX7> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q24392786> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP517_r116994/DataNode/b1f> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/D4ADV8> , <http://purl.uniprot.org/uniprot/A0A8I6GKX7> ;
        foaf:page           <https://www.ensembl.org/id/ENSRNOG00000001708> .

<https://identifiers.org/ncbigene/81751>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "PSEN2" ;
        dc:identifier       <https://identifiers.org/ncbigene/81751> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "81751" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP517_r116994> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSRNOG00000002879> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/81751> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/O88777> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP517_r116994/DataNode/a5b> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/O88777> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/81751> .

<https://identifiers.org/ensembl/ENSRNOG00000017326>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "Ctbp2" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSRNOG00000017326> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSRNOG00000017326" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP517_r116994> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSRNOG00000017326> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/81717> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A8I6ALN3> , <https://identifiers.org/uniprot/Q9EQH5> , <https://identifiers.org/uniprot/A0A8L2QC65> , <https://identifiers.org/uniprot/A0A8I6AEI5> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q24368768> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP517_r116994/DataNode/f7a> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A8I6AEI5> , <http://purl.uniprot.org/uniprot/Q9EQH5> , <http://purl.uniprot.org/uniprot/A0A8L2QC65> , <http://purl.uniprot.org/uniprot/A0A8I6ALN3> ;
        foaf:page           <https://www.ensembl.org/id/ENSRNOG00000017326> .

<https://identifiers.org/ncbigene/297893>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "HDAC1" ;
        dc:identifier       <https://identifiers.org/ncbigene/297893> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "297893" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP517_r116994> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSRNOG00000009568> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/297893> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A8I6AG62> , <https://identifiers.org/uniprot/Q4QQW4> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP517_r116994/DataNode/b6d> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A8I6AG62> , <http://purl.uniprot.org/uniprot/Q4QQW4> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/297893> .

<https://identifiers.org/ncbigene/300802>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "APH1B" ;
        dc:identifier       <https://identifiers.org/ncbigene/300802> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "300802" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP517_r116994> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/300802> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP517_r116994/DataNode/a84> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/300802> .

<https://identifiers.org/ncbigene/83721>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "DVL1" ;
        dc:identifier       <https://identifiers.org/ncbigene/83721> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "83721" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP517_r116994> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSRNOG00000019423> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/83721> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/B1H2A0> , <https://identifiers.org/uniprot/Q9WVB9> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP517_r116994/DataNode/e13> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q9WVB9> , <http://purl.uniprot.org/uniprot/B1H2A0> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/83721> .

<https://identifiers.org/ensembl/ENSRNOG00000023400>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "NP_001102523.1" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSRNOG00000023400> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSRNOG00000023400" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP517_r116994> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSRNOG00000023400> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/498089> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A8I6G788> , <https://identifiers.org/uniprot/D3Z8X6> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q24403900> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP517_r116994/DataNode/cdb> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/D3Z8X6> , <http://purl.uniprot.org/uniprot/A0A8I6G788> ;
        foaf:page           <https://www.ensembl.org/id/ENSRNOG00000023400> .

<https://identifiers.org/pmc/PMC3650681>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed Central" ;
        dcterms:identifier  "PMC3650681" ;
        cito:cites          <https://identifiers.org/wikipathways/WP517> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/PMC3650681> .

<https://identifiers.org/ensembl/ENSRNOG00000003268>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "NP_001100467.1" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSRNOG00000003268> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSRNOG00000003268" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP517_r116994> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSRNOG00000003268> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/303101> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/D4A930> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q24405082> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP517_r116994/DataNode/a43> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/D4A930> ;
        foaf:page           <https://www.ensembl.org/id/ENSRNOG00000003268> .

<https://identifiers.org/ensembl/ENSRNOG00000013333>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "NP_001101145.1" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSRNOG00000013333> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSRNOG00000013333" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP517_r116994> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSRNOG00000013333> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP517_r116994/DataNode/f61> ;
        foaf:page           <https://www.ensembl.org/id/ENSRNOG00000013333> .

<https://identifiers.org/ensembl/ENSRNOG00000009110>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "Psen1" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSRNOG00000009110> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSRNOG00000009110" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP517_r116994> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSRNOG00000009110> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/29192> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/P97887> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q24370883> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP517_r116994/DataNode/f40> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P97887> ;
        foaf:page           <https://www.ensembl.org/id/ENSRNOG00000009110> .

<https://identifiers.org/ensembl/ENSRNOG00000007503>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "Adam17" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSRNOG00000007503> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSRNOG00000007503" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP517_r116994> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSRNOG00000007503> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP517_r116994/DataNode/daf> ;
        foaf:page           <https://www.ensembl.org/id/ENSRNOG00000007503> .

<https://identifiers.org/ensembl/ENSRNOG00000001250>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "Lfng" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSRNOG00000001250> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSRNOG00000001250" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP517_r116994> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSRNOG00000001250> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/170905> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q924T4> , <https://identifiers.org/uniprot/A0A8L2UHG7> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q24420335> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP517_r116994/DataNode/bf7> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q924T4> , <http://purl.uniprot.org/uniprot/A0A8L2UHG7> ;
        foaf:page           <https://www.ensembl.org/id/ENSRNOG00000001250> .

<https://identifiers.org/ensembl/ENSRNOG00000004041>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "Inpp5k" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSRNOG00000004041> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSRNOG00000004041" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP517_r116994/WP/Interaction/d887b> , <https://identifiers.org/wikipathways/WP517_r116994> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSRNOG00000004041> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP517_r116994/DataNode/ef8> ;
        foaf:page           <https://www.ensembl.org/id/ENSRNOG00000004041> .

<https://identifiers.org/ensembl/ENSRNOG00000004346>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "Notch3" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSRNOG00000004346> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSRNOG00000004346" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP517_r116994> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSRNOG00000004346> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/56761> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A8I6AWG8> , <https://identifiers.org/uniprot/F1LQX7> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q24383682> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP517_r116994/DataNode/d9f> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A8I6AWG8> , <http://purl.uniprot.org/uniprot/F1LQX7> ;
        foaf:page           <https://www.ensembl.org/id/ENSRNOG00000004346> .

<https://identifiers.org/wikipathways/WP517>
        pav:hasVersion  <https://identifiers.org/wikipathways/WP517_r116994> .

<https://identifiers.org/ensembl/ENSRNOG00000017915>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "Dvl2" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSRNOG00000017915> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSRNOG00000017915" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP517_r116994> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSRNOG00000017915> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/303251> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/D3ZB71> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q24419353> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP517_r116994/DataNode/ca6> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/D3ZB71> ;
        foaf:page           <https://www.ensembl.org/id/ENSRNOG00000017915> .

<https://identifiers.org/ensembl/ENSRNOG00000018364>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "NP_001100520.1" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSRNOG00000018364> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSRNOG00000018364" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP517_r116994> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSRNOG00000018364> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/303539> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/D4ACX5> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q24372719> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP517_r116994/DataNode/d16> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/D4ACX5> ;
        foaf:page           <https://www.ensembl.org/id/ENSRNOG00000018364> .

<https://identifiers.org/ensembl/ENSRNOG00000018835>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "Notch2" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSRNOG00000018835> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSRNOG00000018835" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP517_r116994> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSRNOG00000018835> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/29492> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A8I6B3I0> , <https://identifiers.org/uniprot/A0A8I6GM47> , <https://identifiers.org/uniprot/A0A1W2Q619> , <https://identifiers.org/uniprot/G3V8G9> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q24391111> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP517_r116994/DataNode/db2> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A8I6B3I0> , <http://purl.uniprot.org/uniprot/A0A1W2Q619> , <http://purl.uniprot.org/uniprot/A0A8I6GM47> , <http://purl.uniprot.org/uniprot/G3V8G9> ;
        foaf:page           <https://www.ensembl.org/id/ENSRNOG00000018835> .

<https://identifiers.org/ensembl/ENSRNOG00000020867>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "Numbl" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSRNOG00000020867> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSRNOG00000020867" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP517_r116994> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSRNOG00000020867> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/292732> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A0G2K9C5> , <https://identifiers.org/uniprot/A1L1I3> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q24372856> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP517_r116994/DataNode/e45> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A0G2K9C5> , <http://purl.uniprot.org/uniprot/A1L1I3> ;
        foaf:page           <https://www.ensembl.org/id/ENSRNOG00000020867> .

<https://identifiers.org/ensembl/ENSRNOG00000000442>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "Notch4" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSRNOG00000000442> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSRNOG00000000442" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP517_r116994> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSRNOG00000000442> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/406162> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q6MG89> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q24372371> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP517_r116994/DataNode/e81> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q6MG89> ;
        foaf:page           <https://www.ensembl.org/id/ENSRNOG00000000442> .

<https://identifiers.org/ensembl/ENSRNOG00000019322>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "NOTC1_RAT" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSRNOG00000019322> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSRNOG00000019322" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP517_r116994> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSRNOG00000019322> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/25496> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q07008> , <https://identifiers.org/uniprot/A0A8I6AT84> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q24410210> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP517_r116994/DataNode/e83> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A8I6AT84> , <http://purl.uniprot.org/uniprot/Q07008> ;
        foaf:page           <https://www.ensembl.org/id/ENSRNOG00000019322> .

<https://identifiers.org/ensembl/ENSRNOG00000001720>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "Hes1" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSRNOG00000001720> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSRNOG00000001720" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP517_r116994> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSRNOG00000001720> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/29577> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/D4ADT9> , <https://identifiers.org/uniprot/Q04666> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q24369175> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP517_r116994/DataNode/f28> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q04666> , <http://purl.uniprot.org/uniprot/D4ADT9> ;
        foaf:page           <https://www.ensembl.org/id/ENSRNOG00000001720> .

<https://identifiers.org/ensembl/ENSRNOG00000007443>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "Jag1" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSRNOG00000007443> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSRNOG00000007443" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP517_r116994> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSRNOG00000007443> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/29146> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/G3V710> , <https://identifiers.org/uniprot/A0A8I6ASU4> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q24420191> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP517_r116994/DataNode/b8c> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A8I6ASU4> , <http://purl.uniprot.org/uniprot/G3V710> ;
        foaf:page           <https://www.ensembl.org/id/ENSRNOG00000007443> .

<https://identifiers.org/wikipathways/WP517_r116994>
        rdf:type               skos:Collection , wp:Pathway ;
        dc:identifier          <https://identifiers.org/wikipathways/WP517> ;
        dc:source              "WikiPathways" ;
        dc:title               "Notch signaling pathway"@en ;
        dcterms:description    "The Notch signaling pathway is an evolutionarily conserved, intercellular signaling mechanism essential for proper embryonic development in all metazoan organisms in the Animal kingdom. The Notch proteins (Notch1-Notch4 in vertebrates) are single-pass receptors that are activated by the Delta (or Delta-like) and Jagged/Serrate families of membrane-bound ligands. They are transported to the plasma membrane as cleaved, but otherwise intact polypeptides. Interaction with ligand leads to two additional proteolytic cleavages that liberate the Notch intracellular domain (NICD) from the plasma membrane. The NICD translocates to the nucleus, where it forms a complex with the DNA binding protein CSL, displacing a histone deacetylase (HDAc)-co-repressor (CoR) complex from CSL. Components of an activation complex, such as MAML1 and histone acetyltransferases (HATs), are recruited to the NICD-CSL complex, leading to the transcriptional activation of Notch target genes." ;
        dcterms:identifier     "WP517" ;
        dcterms:references     <https://identifiers.org/pubmed/9245493> ;
        cito:cites             <https://identifiers.org/pubmed/9245493> ;
        wp:isAbout             <http://rdf.wikipathways.org/Pathway/WP517_r116994> ;
        wp:ontologyTag         wp:Curation:Homology_Converted , obo:PW_0000204 , wp:Curation:AnalysisCollection ;
        wp:organism            obo:NCBITaxon_10116 ;
        wp:organismName        "Rattus norvegicus" ;
        wp:pathwayOntologyTag  obo:PW_0000204 ;
        foaf:img               <https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=svg&pwTitle=Pathway:WP517&oldid=116994> , <https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=png&pwTitle=Pathway:WP517&oldid=116994> ;
        foaf:page              <http://www.wikipathways.org/instance/WP517_r116994> .

<https://identifiers.org/ensembl/ENSRNOG00000014011>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "NP_001101230.1" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSRNOG00000014011> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSRNOG00000014011" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP517_r116994> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSRNOG00000014011> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/311332> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A8L2Q9H8> , <https://identifiers.org/uniprot/D3ZHH1> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q24410160> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP517_r116994/DataNode/e21> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/D3ZHH1> , <http://purl.uniprot.org/uniprot/A0A8L2Q9H8> ;
        foaf:page           <https://www.ensembl.org/id/ENSRNOG00000014011> .

obo:NCBITaxon_10116  obo:NCIT_C179773  "10116" .

<https://identifiers.org/ensembl/ENSRNOG00000023816>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "Aph1a" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSRNOG00000023816> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSRNOG00000023816" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP517_r116994> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSRNOG00000023816> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/365872> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/F7EYZ3> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q24406030> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP517_r116994/DataNode/d60> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/F7EYZ3> ;
        foaf:page           <https://www.ensembl.org/id/ENSRNOG00000023816> .

<https://identifiers.org/ncbigene/29713>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "Kcnj5" ;
        dc:identifier       <https://identifiers.org/ncbigene/29713> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "29713" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP517_r116994> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/29713> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP517_r116994/DataNode/e92> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/29713> .

<https://identifiers.org/ncbigene/60433>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "RFNG" ;
        dc:identifier       <https://identifiers.org/ncbigene/60433> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "60433" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP517_r116994> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSRNOG00000050298> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/60433> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A0G2K5T8> , <https://identifiers.org/uniprot/M0RD65> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP517_r116994/DataNode/e51> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/M0RD65> , <http://purl.uniprot.org/uniprot/A0A0G2K5T8> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/60433> .
