@prefix biopax:  <http://www.biopax.org/release/biopax-level3.owl#> .
@prefix cito:    <http://purl.org/spar/cito/> .
@prefix dc:      <http://purl.org/dc/elements/1.1/> .
@prefix dcterms: <http://purl.org/dc/terms/> .
@prefix foaf:    <http://xmlns.com/foaf/0.1/> .
@prefix freq:    <http://purl.org/cld/freq/> .
@prefix gpml:    <http://vocabularies.wikipathways.org/gpml#> .
@prefix obo:     <http://purl.obolibrary.org/obo/> .
@prefix owl:     <http://www.w3.org/2002/07/owl#> .
@prefix pav:     <http://purl.org/pav/> .
@prefix prov:    <http://www.w3.org/ns/prov#> .
@prefix rdf:     <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix rdfs:    <http://www.w3.org/2000/01/rdf-schema#> .
@prefix skos:    <http://www.w3.org/2004/02/skos/core#> .
@prefix void:    <http://rdfs.org/ns/void#> .
@prefix wp:      <http://vocabularies.wikipathways.org/wp#> .
@prefix wprdf:   <http://rdf.wikipathways.org/> .
@prefix xsd:     <http://www.w3.org/2001/XMLSchema#> .

<https://identifiers.org/wikipathways/WP5531>
        rdf:type            wp:Pathway , wp:DataNode ;
        rdfs:label          "AKT" ;
        dc:identifier       <https://identifiers.org/wikipathways/WP5531> ;
        dc:source           "WikiPathways" ;
        dcterms:identifier  "WP5531" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP5528_r140905> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5528_r140905/DataNode/d3871> ;
        foaf:page           <https://www.wikipathways.org/instance/WP5531> .

<https://identifiers.org/wikipathways/WP5529>
        rdf:type            wp:Pathway , wp:DataNode ;
        rdfs:label          "Wnt/Beta-catenin" ;
        dc:identifier       <https://identifiers.org/wikipathways/WP5529> ;
        dc:source           "WikiPathways" ;
        dcterms:identifier  "WP5529" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP5528_r140905> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5528_r140905/DataNode/b180c> ;
        foaf:page           <https://www.wikipathways.org/instance/WP5529> .

<http://rdf.wikipathways.org/Pathway/WP5528_r140905/Complex/eb568>
        rdf:type          wp:Complex , wp:DataNode ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP5528_r140905> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP5528_r140905/Group/eb568> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000143799> , <https://identifiers.org/interpro/PF00509> .

<http://rdf.wikipathways.org/Pathway/WP5528_r140905/ComplexBinding/eb568>
        rdf:type          wp:ComplexBinding , wp:Binding , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP5528_r140905> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP5528_r140905/Group/eb568> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000143799> , <https://identifiers.org/interpro/PF00509> , <http://rdf.wikipathways.org/Pathway/WP5528_r140905/Complex/eb568> .

<http://rdf.wikipathways.org/Pathway/WP5528_r140905/Complex/ac23a>
        rdf:type          wp:Complex , wp:DataNode ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP5528_r140905> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP5528_r140905/Group/ac23a> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000166888> .

<https://identifiers.org/ensembl/ENSG00000171720>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "HDAC3" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000171720> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000171720" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP5528_r140905> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000171720> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/8841> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/HDAC3> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/O15379> , <https://identifiers.org/uniprot/E7ESJ6> , <https://identifiers.org/uniprot/E7EW19> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18033475> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5528_r140905/DataNode/f2dbb> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/E7EW19> , <http://purl.uniprot.org/uniprot/O15379> , <http://purl.uniprot.org/uniprot/E7ESJ6> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000171720> .

<http://rdf.wikipathways.org/Pathway/WP5528_r140905/ComplexBinding/ac23a>
        rdf:type          wp:ComplexBinding , wp:Binding , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP5528_r140905> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP5528_r140905/Group/ac23a> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000166888> , <http://rdf.wikipathways.org/Pathway/WP5528_r140905/Complex/ac23a> .

<https://identifiers.org/wikipathways/WP5530>
        rdf:type            wp:Pathway , wp:DataNode ;
        rdfs:label          "MAPK" ;
        dc:identifier       <https://identifiers.org/wikipathways/WP5530> ;
        dc:source           "WikiPathways" ;
        dcterms:identifier  "WP5530" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP5528_r140905> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5528_r140905/DataNode/c4055> ;
        foaf:page           <https://www.wikipathways.org/instance/WP5530> .

<http://rdf.wikipathways.org/Pathway/WP5528_r140905/Complex/fdbba>
        rdf:type          wp:Complex , wp:DataNode ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP5528_r140905> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP5528_r140905/Group/fdbba> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000168610> .

<https://identifiers.org/ensembl/ENSG00000143799>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "PARP1" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000143799> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000143799" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP5528_r140905> , <http://rdf.wikipathways.org/Pathway/WP5528_r140905/Complex/eb568> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000143799> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/142> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/PARP1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A7I2V625> , <https://identifiers.org/uniprot/A0A024R3T8> , <https://identifiers.org/uniprot/A0A7I2V5E9> , <https://identifiers.org/uniprot/P09874> , <https://identifiers.org/uniprot/A0A7I2V384> , <https://identifiers.org/uniprot/A0A7I2V3E1> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q17710375> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5528_r140905/DataNode/f75ab> , <http://rdf.wikipathways.org/Pathway/WP5528_r140905/DataNode/ef678> , <http://rdf.wikipathways.org/Pathway/WP5528_r140905/DataNode/e128c> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A7I2V3E1> , <http://purl.uniprot.org/uniprot/P09874> , <http://purl.uniprot.org/uniprot/A0A7I2V5E9> , <http://purl.uniprot.org/uniprot/A0A024R3T8> , <http://purl.uniprot.org/uniprot/A0A7I2V625> , <http://purl.uniprot.org/uniprot/A0A7I2V384> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000143799> .

<https://identifiers.org/ensembl/ENSG00000138496>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "PARP9" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000138496> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000138496" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP5528_r140905> , <http://rdf.wikipathways.org/Pathway/WP5528_r140905/Complex/ed78e> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000138496> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/83666> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/PARP9> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q8IXQ6> , <https://identifiers.org/uniprot/G5E9U8> , <https://identifiers.org/uniprot/C9K0E5> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18047231> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5528_r140905/DataNode/cd914> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/C9K0E5> , <http://purl.uniprot.org/uniprot/Q8IXQ6> , <http://purl.uniprot.org/uniprot/G5E9U8> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000138496> .

<http://rdf.wikipathways.org/Pathway/WP5528_r140905/ComplexBinding/fdbba>
        rdf:type          wp:ComplexBinding , wp:Binding , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP5528_r140905> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP5528_r140905/Group/fdbba> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000168610> , <http://rdf.wikipathways.org/Pathway/WP5528_r140905/Complex/fdbba> .

<https://identifiers.org/wikipathways/WP5528>
        rdf:type            wp:DataNode , wp:Pathway ;
        rdfs:label          "JAK/STAT" ;
        dc:identifier       <https://identifiers.org/wikipathways/WP5528> ;
        dc:source           "WikiPathways" ;
        dcterms:identifier  "WP5528" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP5528_r140905> ;
        pav:hasVersion      <https://identifiers.org/wikipathways/WP5528_r140905> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5528_r140905/DataNode/ed419> ;
        foaf:page           <https://www.wikipathways.org/instance/WP5528> .

<https://identifiers.org/ensembl/ENSG00000196591>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "HDAC2" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000196591> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000196591" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP5528_r140905> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000196591> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/3066> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/HDAC2> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/E5RK19> , <https://identifiers.org/uniprot/Q92769> , <https://identifiers.org/uniprot/E5RG37> , <https://identifiers.org/uniprot/E5RGV4> , <https://identifiers.org/uniprot/E5RJ04> , <https://identifiers.org/uniprot/H3BM24> , <https://identifiers.org/uniprot/E5RFI6> , <https://identifiers.org/uniprot/E5RHE7> , <https://identifiers.org/uniprot/E5RH52> , <https://identifiers.org/uniprot/E5RFP9> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18026859> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5528_r140905/DataNode/dfd4c> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/E5RFP9> , <http://purl.uniprot.org/uniprot/Q92769> , <http://purl.uniprot.org/uniprot/E5RGV4> , <http://purl.uniprot.org/uniprot/E5RK19> , <http://purl.uniprot.org/uniprot/E5RG37> , <http://purl.uniprot.org/uniprot/E5RFI6> , <http://purl.uniprot.org/uniprot/E5RHE7> , <http://purl.uniprot.org/uniprot/E5RJ04> , <http://purl.uniprot.org/uniprot/H3BM24> , <http://purl.uniprot.org/uniprot/E5RH52> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000196591> .

<https://identifiers.org/ensembl/ENSG00000113558>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "SKP1" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000113558> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000113558" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP5528_r140905> , <http://rdf.wikipathways.org/Pathway/WP5528_r140905/Complex/c550c> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000113558> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/6500> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/SKP1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/E5RK33> , <https://identifiers.org/uniprot/E5RJR5> , <https://identifiers.org/uniprot/E5RHM3> , <https://identifiers.org/uniprot/F8W8N3> , <https://identifiers.org/uniprot/E5RGM3> , <https://identifiers.org/uniprot/E5RGM4> , <https://identifiers.org/uniprot/P63208> , <https://identifiers.org/uniprot/E7ERH2> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18031515> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5528_r140905/DataNode/f05e9> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/E5RHM3> , <http://purl.uniprot.org/uniprot/E5RGM4> , <http://purl.uniprot.org/uniprot/E5RK33> , <http://purl.uniprot.org/uniprot/P63208> , <http://purl.uniprot.org/uniprot/E7ERH2> , <http://purl.uniprot.org/uniprot/E5RJR5> , <http://purl.uniprot.org/uniprot/E5RGM3> , <http://purl.uniprot.org/uniprot/F8W8N3> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000113558> .

<http://rdf.wikipathways.org/Pathway/WP5528_r140905/WP/Interaction/e15c0_2>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP5528_r140905> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP5528_r140905/Interaction/e15c0> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000173193> , <https://identifiers.org/ensembl/ENSG00000115415> ;
        wp:source         <https://identifiers.org/ensembl/ENSG00000173193> ;
        wp:target         <https://identifiers.org/ensembl/ENSG00000115415> .

<https://identifiers.org/ensembl/ENSG00000055130>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "CUL1" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000055130> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000055130" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP5528_r140905> , <http://rdf.wikipathways.org/Pathway/WP5528_r140905/Complex/c550c> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000055130> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/8454> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/CUL1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q13616> , <https://identifiers.org/uniprot/A0A590UJR3> , <https://identifiers.org/uniprot/A0A090N7U0> , <https://identifiers.org/uniprot/A0A590UJ21> , <https://identifiers.org/uniprot/A0A590UK34> , <https://identifiers.org/uniprot/A0A590UJ50> , <https://identifiers.org/uniprot/A0A590UJ97> , <https://identifiers.org/uniprot/A0A590UJA0> , <https://identifiers.org/uniprot/A0A590UJM8> , <https://identifiers.org/uniprot/A0A590UJ56> , <https://identifiers.org/uniprot/A0A590UJC4> , <https://identifiers.org/uniprot/A0A590UJ59> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18032946> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5528_r140905/DataNode/ba798> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A590UJ56> , <http://purl.uniprot.org/uniprot/A0A590UJA0> , <http://purl.uniprot.org/uniprot/A0A590UJ97> , <http://purl.uniprot.org/uniprot/A0A590UJ50> , <http://purl.uniprot.org/uniprot/A0A590UJR3> , <http://purl.uniprot.org/uniprot/A0A590UK34> , <http://purl.uniprot.org/uniprot/Q13616> , <http://purl.uniprot.org/uniprot/A0A590UJC4> , <http://purl.uniprot.org/uniprot/A0A590UJM8> , <http://purl.uniprot.org/uniprot/A0A090N7U0> , <http://purl.uniprot.org/uniprot/A0A590UJ21> , <http://purl.uniprot.org/uniprot/A0A590UJ59> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000055130> .

<https://identifiers.org/ensembl/ENSG00000166888>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "STAT6" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000166888> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000166888" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP5528_r140905> , <http://rdf.wikipathways.org/Pathway/WP5528_r140905/Complex/ac23a> , <http://rdf.wikipathways.org/Pathway/WP5528_r140905/WP/Interaction/ac800> , <http://rdf.wikipathways.org/Pathway/WP5528_r140905/Complex/fdc41> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000166888> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/6778> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/STAT6> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/G3V2H4> , <https://identifiers.org/uniprot/H0YJH6> , <https://identifiers.org/uniprot/G3V5I8> , <https://identifiers.org/uniprot/A0A494C0T4> , <https://identifiers.org/uniprot/Q5FBW6> , <https://identifiers.org/uniprot/H0YIY2> , <https://identifiers.org/uniprot/G3V370> , <https://identifiers.org/uniprot/A0A1W2PNW1> , <https://identifiers.org/uniprot/G3V2L2> , <https://identifiers.org/uniprot/G3V568> , <https://identifiers.org/uniprot/G3V5K5> , <https://identifiers.org/uniprot/G3V2M3> , <https://identifiers.org/uniprot/P42226> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q14914613> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5528_r140905/DataNode/cfdf0> , <http://rdf.wikipathways.org/Pathway/WP5528_r140905/DataNode/eb3b3> , <http://rdf.wikipathways.org/Pathway/WP5528_r140905/DataNode/cccb1> , <http://rdf.wikipathways.org/Pathway/WP5528_r140905/DataNode/c45ac> , <http://rdf.wikipathways.org/Pathway/WP5528_r140905/DataNode/bf763> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/H0YIY2> , <http://purl.uniprot.org/uniprot/G3V2L2> , <http://purl.uniprot.org/uniprot/G3V5K5> , <http://purl.uniprot.org/uniprot/P42226> , <http://purl.uniprot.org/uniprot/G3V2M3> , <http://purl.uniprot.org/uniprot/Q5FBW6> , <http://purl.uniprot.org/uniprot/A0A494C0T4> , <http://purl.uniprot.org/uniprot/A0A1W2PNW1> , <http://purl.uniprot.org/uniprot/G3V370> , <http://purl.uniprot.org/uniprot/G3V5I8> , <http://purl.uniprot.org/uniprot/H0YJH6> , <http://purl.uniprot.org/uniprot/G3V2H4> , <http://purl.uniprot.org/uniprot/G3V568> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000166888> .

<https://identifiers.org/wikipathways/WP5527>
        rdf:type            wp:Pathway , wp:DataNode ;
        rdfs:label          "NF-kB" ;
        dc:identifier       <https://identifiers.org/wikipathways/WP5527> ;
        dc:source           "WikiPathways" ;
        dcterms:identifier  "WP5527" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP5528_r140905> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5528_r140905/DataNode/ea096> ;
        foaf:page           <https://www.wikipathways.org/instance/WP5527> .

<http://rdf.wikipathways.org/Pathway/WP5528_r140905/Complex/b2d7f>
        rdf:type          wp:Complex , wp:DataNode ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP5528_r140905> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP5528_r140905/Group/b2d7f> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000115415> .

<https://identifiers.org/ensembl/ENSG00000100387>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "RBX1" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000100387> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000100387" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP5528_r140905> , <http://rdf.wikipathways.org/Pathway/WP5528_r140905/Complex/c550c> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000100387> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/9978> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/RBX1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/P62877> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18034928> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5528_r140905/DataNode/cbf8c> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P62877> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000100387> .

<https://identifiers.org/ensembl/ENSG00000115415>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "STAT1" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000115415> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000115415" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP5528_r140905/WP/Interaction/e15c0_1> , <https://identifiers.org/wikipathways/WP5528_r140905> , <http://rdf.wikipathways.org/Pathway/WP5528_r140905/Complex/fe7db> , <http://rdf.wikipathways.org/Pathway/WP5528_r140905/Complex/b2d7f> , <http://rdf.wikipathways.org/Pathway/WP5528_r140905/WP/Interaction/e15c0_2> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000115415> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/6772> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/STAT1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/E9PH66> , <https://identifiers.org/uniprot/A0A669KB75> , <https://identifiers.org/uniprot/P42224> , <https://identifiers.org/uniprot/Q67C41> , <https://identifiers.org/uniprot/A0A669KB17> , <https://identifiers.org/uniprot/E7ENM1> , <https://identifiers.org/uniprot/A0A669KBA4> , <https://identifiers.org/uniprot/A0A8V8TMY9> , <https://identifiers.org/uniprot/A0A669KB68> , <https://identifiers.org/uniprot/J3KPM9> , <https://identifiers.org/uniprot/E7EPD2> , <https://identifiers.org/uniprot/A0A669KB56> , <https://identifiers.org/uniprot/A0A669KB53> , <https://identifiers.org/uniprot/A0A8V8TN81> , <https://identifiers.org/uniprot/A0A8V8TLI6> , <https://identifiers.org/uniprot/D2KFR9> , <https://identifiers.org/uniprot/A0A669KBK4> , <https://identifiers.org/uniprot/A0A669KBI6> , <https://identifiers.org/uniprot/A0A669KB52> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q14912030> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5528_r140905/DataNode/ad5f2> , <http://rdf.wikipathways.org/Pathway/WP5528_r140905/DataNode/c5e94> , <http://rdf.wikipathways.org/Pathway/WP5528_r140905/DataNode/f2ffb> , <http://rdf.wikipathways.org/Pathway/WP5528_r140905/DataNode/c81ee> , <http://rdf.wikipathways.org/Pathway/WP5528_r140905/DataNode/b5e4f> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/E7EPD2> , <http://purl.uniprot.org/uniprot/D2KFR9> , <http://purl.uniprot.org/uniprot/A0A8V8TLI6> , <http://purl.uniprot.org/uniprot/A0A669KB68> , <http://purl.uniprot.org/uniprot/Q67C41> , <http://purl.uniprot.org/uniprot/A0A669KBI6> , <http://purl.uniprot.org/uniprot/A0A669KB56> , <http://purl.uniprot.org/uniprot/A0A669KB52> , <http://purl.uniprot.org/uniprot/A0A669KBK4> , <http://purl.uniprot.org/uniprot/E9PH66> , <http://purl.uniprot.org/uniprot/A0A8V8TN81> , <http://purl.uniprot.org/uniprot/A0A669KB75> , <http://purl.uniprot.org/uniprot/A0A8V8TMY9> , <http://purl.uniprot.org/uniprot/A0A669KB17> , <http://purl.uniprot.org/uniprot/A0A669KB53> , <http://purl.uniprot.org/uniprot/P42224> , <http://purl.uniprot.org/uniprot/A0A669KBA4> , <http://purl.uniprot.org/uniprot/J3KPM9> , <http://purl.uniprot.org/uniprot/E7ENM1> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000115415> .

<http://rdf.wikipathways.org/Pathway/WP5528_r140905/Complex/fdc41>
        rdf:type          wp:Complex , wp:DataNode ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP5528_r140905> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP5528_r140905/Group/fdc41> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000166888> .

<http://rdf.wikipathways.org/Pathway/WP5528_r140905/ComplexBinding/fdc41>
        rdf:type          wp:ComplexBinding , wp:Binding , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP5528_r140905> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP5528_r140905/Group/fdc41> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000166888> , <http://rdf.wikipathways.org/Pathway/WP5528_r140905/Complex/fdc41> .

<https://identifiers.org/ensembl/ENSG00000173193>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "PARP14" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000173193> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000173193" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP5528_r140905> , <http://rdf.wikipathways.org/Pathway/WP5528_r140905/WP/Interaction/e15c0_1> , <http://rdf.wikipathways.org/Pathway/WP5528_r140905/WP/Interaction/e15c0_2> , <http://rdf.wikipathways.org/Pathway/WP5528_r140905/WP/Interaction/ac800> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000173193> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/54625> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/PARP14> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/H7C4Y3> , <https://identifiers.org/uniprot/A0A3B3ITD5> , <https://identifiers.org/uniprot/H7C5R8> , <https://identifiers.org/uniprot/Q460N5> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18041139> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5528_r140905/DataNode/b688e> , <http://rdf.wikipathways.org/Pathway/WP5528_r140905/DataNode/aaa8f> , <http://rdf.wikipathways.org/Pathway/WP5528_r140905/DataNode/dc879> , <http://rdf.wikipathways.org/Pathway/WP5528_r140905/DataNode/b93c9> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/H7C4Y3> , <http://purl.uniprot.org/uniprot/A0A3B3ITD5> , <http://purl.uniprot.org/uniprot/H7C5R8> , <http://purl.uniprot.org/uniprot/Q460N5> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000173193> .

obo:NCBITaxon_9606  obo:NCIT_C179773  "9606" .

<https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=svg&pwTitle=Pathway:WP5528&oldid=140905>
        rdf:type        foaf:Image ;
        dcterms:format  "image/svg+xml" .

<https://identifiers.org/wikipathways/WP5528_r140905>
        rdf:type                wp:Pathway , skos:Collection ;
        dc:identifier           <https://identifiers.org/wikipathways/WP5528> ;
        dc:source               "WikiPathways" ;
        dc:title                "JAK/STAT signaling and ARTD family members"@en ;
        dcterms:description     "Both PARP9 (ARTD9) and PARP14 are highly expressed and undergo increased ADP-ribosylation in IFNγ-stimulated THP-1 cells. Notably, PARP9 and PARP14 have opposing roles in macrophages, with PARP9 promoting anti-inflammatory effects and PARP14 enhancing proinflammatory responses, thus regulating macrophage activation. Additionally, the expression of PARP9 is controlled by the IFNγ-JAK2/STAT1-IRF1 signaling pathway, which is essential for the survival of cancer cells in diffuse large B-cell lymphoma (DLBCL) with an active host inflammatory response.\n\n*Positive regulation*\nIn macrophages, the phosphorylation of STAT6 induced by IL-4 and the subsequent activation of anti-inflammatory genes depend on the activation of PARP14, which likely involves PARP14-mediated ADP-ribosylation of STAT6. The role of PARP14 in the ADP-ribosylation of STAT6 for gene activation presents a potential therapeutic target to mitigate the progression of allergic airway diseases.\n\nPARP1 positively influences STAT6-dependent transcriptional activation. Reduced PARP1 levels lead to decreased STAT6 protein stability, resulting in lowered IL-5 expression in murine splenocytes. Moreover, excessive activation of PARP1, causing NAD+ depletion, is believed to contribute to the development of various cardiovascular diseases, such as atherosclerosis and cardiac hypertrophy.\n\nIn a phenylephrine-induced cardiac hypertrophy model, PARP1 and its enzymatic activity help retain phosphorylated STAT3 in the nucleus, extending its transcriptional activity independent of JAK2, which contributes to the hypertrophy phenotype.\n\nPARP9, in association with its binding partner DTX3L, is involved in STAT1-mediated interferon signaling. The PARP9/DTX3L complex is a key factor regulating STAT1 transcriptional activity and enhances the host defense response following viral infection. In DLBCL, PARP9 stimulates the phosphorylation of both STAT1 isoforms, particularly promoting the nuclear accumulation of the transcriptionally repressive STAT1β isoform. PARP9, together with STAT1β, inhibits the expression of the tumor suppressor IRF1, while enhancing the expression of proto-oncogenes such as IRF2 and BCL6. In this context, PARP9 suppresses the anti-proliferative and pro-apoptotic IFNγ-STAT1-IRF1-p53 pathway, thereby promoting cell proliferation and survival in DLBCL.\n\n*Negative regulation*\n\nViral infection triggers the expression of PARP11 (ARTD11), which mono-ADP-ribosylates the E3 ubiquitin ligase β-TrCP. This modification leads to the ubiquitination and degradation of IFNAR1, ultimately suppressing the IFN antiviral signaling pathway.\n\nIn response to influenza A viral infection, PARP1 transiently co-localizes with HA in the cytoplasm, mediating the degradation of IFNAR1 in an ADP-ribosylation-dependent manner.\n\nIn ovarian, lung, and colon cancer cell lines, PARP1 downregulates PD-L1 expression by ADP-ribosylating STAT3, which decreases its phosphorylation. This contrasts with the positive regulation of STAT3 described earlier, highlighting the context-dependent regulation of STAT3 by PARP1." ;
        dcterms:identifier      "WP5528" ;
        dcterms:references      <https://identifiers.org/pubmed/34725336> ;
        cito:cites              <https://identifiers.org/pubmed/34725336> ;
        wp:cellTypeOntologyTag  obo:CL_0000235 , obo:CL_2000074 ;
        wp:diseaseOntologyTag   obo:DOID_2394 , obo:DOID_0050745 , obo:DOID_1324 , obo:DOID_219 ;
        wp:isAbout              <http://rdf.wikipathways.org/Pathway/WP5528_r140905> ;
        wp:ontologyTag          obo:CL_2000074 , obo:CL_0000235 , obo:PW_0000209 , wp:Curation:AnalysisCollection , obo:DOID_1324 , obo:DOID_2394 , wp:Curation:CPTAC , obo:DOID_219 , obo:DOID_0050745 ;
        wp:organism             obo:NCBITaxon_9606 ;
        wp:organismName         "Homo sapiens" ;
        wp:pathwayOntologyTag   obo:PW_0000209 ;
        foaf:img                <https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=svg&pwTitle=Pathway:WP5528&oldid=140905> , <https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=png&pwTitle=Pathway:WP5528&oldid=140905> ;
        foaf:page               <http://www.wikipathways.org/instance/WP5528_r140905> .

<http://rdf.wikipathways.org/Pathway/WP5528_r140905/WP/Interaction/e15c0_1>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP5528_r140905> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP5528_r140905/Interaction/e15c0> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000173193> , <https://identifiers.org/ensembl/ENSG00000115415> ;
        wp:source         <https://identifiers.org/ensembl/ENSG00000115415> ;
        wp:target         <https://identifiers.org/ensembl/ENSG00000173193> .

<http://rdf.wikipathways.org/Pathway/WP5528_r140905/Complex/c550c>
        rdf:type          wp:Complex , wp:DataNode ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP5528_r140905> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP5528_r140905/Group/c550c> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000166167> , <https://identifiers.org/ensembl/ENSG00000055130> , <https://identifiers.org/ensembl/ENSG00000113558> , <https://identifiers.org/ensembl/ENSG00000100387> .

<http://rdf.wikipathways.org/Pathway/WP5528_r140905/Complex/fe7db>
        rdf:type          wp:Complex , wp:DataNode ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP5528_r140905> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP5528_r140905/Group/fe7db> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000115415> .

<http://rdf.wikipathways.org/Pathway/WP5528_r140905/ComplexBinding/c550c>
        rdf:type          wp:Binding , wp:Interaction , wp:ComplexBinding ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP5528_r140905> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP5528_r140905/Group/c550c> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000113558> , <http://rdf.wikipathways.org/Pathway/WP5528_r140905/Complex/c550c> , <https://identifiers.org/ensembl/ENSG00000100387> , <https://identifiers.org/ensembl/ENSG00000166167> , <https://identifiers.org/ensembl/ENSG00000055130> .

<http://rdf.wikipathways.org/Pathway/WP5528_r140905/ComplexBinding/fe7db>
        rdf:type          wp:ComplexBinding , wp:Binding , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP5528_r140905> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP5528_r140905/Group/fe7db> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000115415> , <http://rdf.wikipathways.org/Pathway/WP5528_r140905/Complex/fe7db> .

<https://identifiers.org/pubmed/34725336>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "34725336" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP5528_r140905> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/34725336> .

<http://rdf.wikipathways.org/Pathway/WP5528_r140905/Complex/bfc3d>
        rdf:type          wp:Complex , wp:DataNode ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP5528_r140905> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP5528_r140905/Group/bfc3d> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000168610> .

<http://rdf.wikipathways.org/Pathway/WP5528_r140905/ComplexBinding/bfc3d>
        rdf:type          wp:ComplexBinding , wp:Binding , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP5528_r140905> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP5528_r140905/Group/bfc3d> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000168610> , <http://rdf.wikipathways.org/Pathway/WP5528_r140905/Complex/bfc3d> .

<https://identifiers.org/ensembl/ENSG00000111224>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "PARP11" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000111224> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000111224" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP5528_r140905> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000111224> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/57097> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/PARP11> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/F8WFA3> , <https://identifiers.org/uniprot/F5H8L8> , <https://identifiers.org/uniprot/G3V0I3> , <https://identifiers.org/uniprot/Q9NR21> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18042884> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5528_r140905/DataNode/a126f> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/F8WFA3> , <http://purl.uniprot.org/uniprot/F5H8L8> , <http://purl.uniprot.org/uniprot/Q9NR21> , <http://purl.uniprot.org/uniprot/G3V0I3> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000111224> .

<http://rdf.wikipathways.org/Pathway/WP5528_r140905/ComplexBinding/b2d7f>
        rdf:type          wp:ComplexBinding , wp:Binding , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP5528_r140905> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP5528_r140905/Group/b2d7f> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000115415> , <http://rdf.wikipathways.org/Pathway/WP5528_r140905/Complex/b2d7f> .

<https://identifiers.org/ensembl/ENSG00000166167>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "BTRC" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000166167> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000166167" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP5528_r140905/Complex/c550c> , <https://identifiers.org/wikipathways/WP5528_r140905> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000166167> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/8945> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/BTRC> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A0S2Z4P6> , <https://identifiers.org/uniprot/B7Z3H4> , <https://identifiers.org/uniprot/Q5T1W7> , <https://identifiers.org/uniprot/Q9Y297> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18033554> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5528_r140905/DataNode/cfca2> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q5T1W7> , <http://purl.uniprot.org/uniprot/B7Z3H4> , <http://purl.uniprot.org/uniprot/Q9Y297> , <http://purl.uniprot.org/uniprot/A0A0S2Z4P6> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000166167> .

<https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=png&pwTitle=Pathway:WP5528&oldid=140905>
        rdf:type        foaf:Image ;
        dcterms:format  "image/png" .

<https://identifiers.org/ensembl/ENSG00000168610>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "STAT3" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000168610> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000168610" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP5528_r140905/Complex/fdbba> , <http://rdf.wikipathways.org/Pathway/WP5528_r140905/Complex/bfc3d> , <https://identifiers.org/wikipathways/WP5528_r140905> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000168610> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/6774> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/STAT3> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A7I2V444> , <https://identifiers.org/uniprot/A0A7I2V552> , <https://identifiers.org/uniprot/A0A7I2YQI1> , <https://identifiers.org/uniprot/A0A7I2V4F6> , <https://identifiers.org/uniprot/A0A7I2V4R2> , <https://identifiers.org/uniprot/A0A7I2V4C8> , <https://identifiers.org/uniprot/G8JLH9> , <https://identifiers.org/uniprot/A0A7I2V395> , <https://identifiers.org/uniprot/A0A7I2V3V0> , <https://identifiers.org/uniprot/A0A7I2V5N9> , <https://identifiers.org/uniprot/P40763> , <https://identifiers.org/uniprot/A0A7I2V2T1> , <https://identifiers.org/uniprot/A0A7I2V4R3> , <https://identifiers.org/uniprot/A0A7I2V2G1> , <https://identifiers.org/uniprot/A0A7I2YQR5> , <https://identifiers.org/uniprot/A0A7I2YQD2> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q14912019> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5528_r140905/DataNode/b6fbd> , <http://rdf.wikipathways.org/Pathway/WP5528_r140905/DataNode/da122> , <http://rdf.wikipathways.org/Pathway/WP5528_r140905/DataNode/adb16> , <http://rdf.wikipathways.org/Pathway/WP5528_r140905/DataNode/ee18c> , <http://rdf.wikipathways.org/Pathway/WP5528_r140905/DataNode/b2ac5> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A7I2YQI1> , <http://purl.uniprot.org/uniprot/P40763> , <http://purl.uniprot.org/uniprot/A0A7I2V552> , <http://purl.uniprot.org/uniprot/A0A7I2V444> , <http://purl.uniprot.org/uniprot/A0A7I2YQD2> , <http://purl.uniprot.org/uniprot/A0A7I2V4R2> , <http://purl.uniprot.org/uniprot/A0A7I2V3V0> , <http://purl.uniprot.org/uniprot/A0A7I2V2G1> , <http://purl.uniprot.org/uniprot/A0A7I2V395> , <http://purl.uniprot.org/uniprot/A0A7I2V4C8> , <http://purl.uniprot.org/uniprot/A0A7I2V5N9> , <http://purl.uniprot.org/uniprot/A0A7I2YQR5> , <http://purl.uniprot.org/uniprot/A0A7I2V4R3> , <http://purl.uniprot.org/uniprot/A0A7I2V2T1> , <http://purl.uniprot.org/uniprot/A0A7I2V4F6> , <http://purl.uniprot.org/uniprot/G8JLH9> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000168610> .

<https://identifiers.org/interpro/PF00509>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "Hemagglutinin" ;
        dc:identifier       <https://identifiers.org/interpro/PF00509> ;
        dc:source           "InterPro" ;
        dcterms:identifier  "PF00509" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP5528_r140905> , <http://rdf.wikipathways.org/Pathway/WP5528_r140905/Complex/eb568> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5528_r140905/DataNode/efae4> ;
        foaf:page           <https://www.ebi.ac.uk/interpro/entry/InterPro/PF00509> .

<http://rdf.wikipathways.org/Pathway/WP5528_r140905/WP/Interaction/ac800>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP5528_r140905> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP5528_r140905/Interaction/ac800> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000166888> , <https://identifiers.org/ensembl/ENSG00000173193> ;
        wp:source         <https://identifiers.org/ensembl/ENSG00000173193> ;
        wp:target         <https://identifiers.org/ensembl/ENSG00000166888> .

<https://identifiers.org/ensembl/ENSG00000163840>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "DTX3L" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000163840> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000163840" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP5528_r140905> , <http://rdf.wikipathways.org/Pathway/WP5528_r140905/Complex/ed78e> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000163840> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/151636> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/DTX3L> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q8TDB6> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18052022> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5528_r140905/DataNode/ec44e> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q8TDB6> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000163840> .

<http://rdf.wikipathways.org/Pathway/WP5528_r140905/Complex/ed78e>
        rdf:type          wp:Complex , wp:DataNode ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP5528_r140905> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP5528_r140905/Group/ed78e> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000163840> , <https://identifiers.org/ensembl/ENSG00000138496> .

<http://rdf.wikipathways.org/Pathway/WP5528_r140905/ComplexBinding/ed78e>
        rdf:type          wp:ComplexBinding , wp:Binding , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP5528_r140905> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP5528_r140905/Group/ed78e> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000163840> , <https://identifiers.org/ensembl/ENSG00000138496> , <http://rdf.wikipathways.org/Pathway/WP5528_r140905/Complex/ed78e> .
