@prefix biopax:  <http://www.biopax.org/release/biopax-level3.owl#> .
@prefix cito:    <http://purl.org/spar/cito/> .
@prefix dc:      <http://purl.org/dc/elements/1.1/> .
@prefix dcterms: <http://purl.org/dc/terms/> .
@prefix foaf:    <http://xmlns.com/foaf/0.1/> .
@prefix freq:    <http://purl.org/cld/freq/> .
@prefix gpml:    <http://vocabularies.wikipathways.org/gpml#> .
@prefix obo:     <http://purl.obolibrary.org/obo/> .
@prefix owl:     <http://www.w3.org/2002/07/owl#> .
@prefix pav:     <http://purl.org/pav/> .
@prefix prov:    <http://www.w3.org/ns/prov#> .
@prefix rdf:     <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix rdfs:    <http://www.w3.org/2000/01/rdf-schema#> .
@prefix skos:    <http://www.w3.org/2004/02/skos/core#> .
@prefix void:    <http://rdfs.org/ns/void#> .
@prefix wp:      <http://vocabularies.wikipathways.org/wp#> .
@prefix wprdf:   <http://rdf.wikipathways.org/> .
@prefix xsd:     <http://www.w3.org/2001/XMLSchema#> .

<http://rdf.wikipathways.org/Pathway/WP3282_r140023/WP/Interaction/id6f3349d2>
        rdf:type          wp:Inhibition , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP3282_r140023> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP3282_r140023/Interaction/id6f3349d2> ;
        wp:participants   <https://identifiers.org/hmdb/HMDB0010147> , <https://identifiers.org/ensembl/ENSBTAG00000020294> ;
        wp:source         <https://identifiers.org/ensembl/ENSBTAG00000020294> ;
        wp:target         <https://identifiers.org/hmdb/HMDB0010147> .

<https://identifiers.org/ensembl/ENSBTAG00000048057>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "GSK3B" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSBTAG00000048057> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSBTAG00000048057" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP3282_r140023> , <http://rdf.wikipathways.org/Pathway/WP3282_r140023/Complex/daadd> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSBTAG00000048057> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/790875> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A3Q1LMN7> , <https://identifiers.org/uniprot/G3N1T2> , <https://identifiers.org/uniprot/A0A3Q1MT31> , <https://identifiers.org/uniprot/F1MIC3> , <https://identifiers.org/uniprot/A0A3Q1NDU7> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP3282_r140023/DataNode/fd8f4> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/F1MIC3> , <http://purl.uniprot.org/uniprot/A0A3Q1MT31> , <http://purl.uniprot.org/uniprot/A0A3Q1LMN7> , <http://purl.uniprot.org/uniprot/G3N1T2> , <http://purl.uniprot.org/uniprot/A0A3Q1NDU7> ;
        foaf:page           <https://www.ensembl.org/id/ENSBTAG00000048057> .

<https://identifiers.org/ensembl/ENSBTAG00000012695>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "LCK" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSBTAG00000012695> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSBTAG00000012695" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP3282_r140023> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSBTAG00000012695> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/508890> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A3Q1MDN9> , <https://identifiers.org/uniprot/Q3ZCM0> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP3282_r140023/DataNode/dde01> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q3ZCM0> , <http://purl.uniprot.org/uniprot/A0A3Q1MDN9> ;
        foaf:page           <https://www.ensembl.org/id/ENSBTAG00000012695> .

<https://identifiers.org/ensembl/ENSBTAG00000016836>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "PDK1" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSBTAG00000016836> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSBTAG00000016836" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP3282_r140023/WP/Interaction/idaf4f9a86> , <http://rdf.wikipathways.org/Pathway/WP3282_r140023/WP/Interaction/id54643aa6> , <https://identifiers.org/wikipathways/WP3282_r140023> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSBTAG00000016836> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/528655> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/E1B8C5> , <https://identifiers.org/uniprot/A0A3Q1LYU1> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP3282_r140023/DataNode/b6cf9> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A3Q1LYU1> , <http://purl.uniprot.org/uniprot/E1B8C5> ;
        foaf:page           <https://www.ensembl.org/id/ENSBTAG00000016836> .

<https://identifiers.org/ensembl/ENSBTAG00000020883>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "IL2" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSBTAG00000020883> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSBTAG00000020883" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP3282_r140023/WP/Interaction/iddf233a60> , <https://identifiers.org/wikipathways/WP3282_r140023> , <http://rdf.wikipathways.org/Pathway/WP3282_r140023/WP/Interaction/ida06fc4da> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSBTAG00000020883> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/280822> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/P05016> , <https://identifiers.org/uniprot/B2BB68> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP3282_r140023/DataNode/b595a> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P05016> , <http://purl.uniprot.org/uniprot/B2BB68> ;
        foaf:page           <https://www.ensembl.org/id/ENSBTAG00000020883> .

<https://identifiers.org/ensembl/ENSBTAG00000008956>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "CD8B" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSBTAG00000008956> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSBTAG00000008956" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP3282_r140023> , <http://rdf.wikipathways.org/Pathway/WP3282_r140023/Complex/b8142> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSBTAG00000008956> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/508633> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A7YW30> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP3282_r140023/DataNode/c363d> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A7YW30> ;
        foaf:page           <https://www.ensembl.org/id/ENSBTAG00000008956> .

<https://identifiers.org/ensembl/ENSBTAG00000005892>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "ZAP70" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSBTAG00000005892> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSBTAG00000005892" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP3282_r140023> , <http://rdf.wikipathways.org/Pathway/WP3282_r140023/WP/Interaction/id2489f199> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSBTAG00000005892> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/504509> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/E1BMP9> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP3282_r140023/DataNode/f346f> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/E1BMP9> ;
        foaf:page           <https://www.ensembl.org/id/ENSBTAG00000005892> .

<http://rdf.wikipathways.org/Pathway/WP3282_r140023/WP/Interaction/id12ffba13>
        rdf:type          wp:Inhibition , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP3282_r140023> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP3282_r140023/Interaction/id12ffba13> ;
        wp:participants   <https://identifiers.org/ensembl/ENSBTAG00000020270> , <https://identifiers.org/ensembl/ENSBTAG00000016683> ;
        wp:source         <https://identifiers.org/ensembl/ENSBTAG00000016683> ;
        wp:target         <https://identifiers.org/ensembl/ENSBTAG00000020270> .

<http://rdf.wikipathways.org/Pathway/WP3282_r140023/WP/Interaction/idf1fab056>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP3282_r140023> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP3282_r140023/Interaction/idf1fab056> ;
        wp:participants   <https://identifiers.org/ensembl/ENSBTAG00000020294> , <https://identifiers.org/ensembl/ENSBTAG00000011543> ;
        wp:source         <https://identifiers.org/ensembl/ENSBTAG00000011543> ;
        wp:target         <https://identifiers.org/ensembl/ENSBTAG00000020294> .

<http://rdf.wikipathways.org/Pathway/WP3282_r140023/WP/Interaction/b2840>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP3282_r140023> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP3282_r140023/Interaction/b2840> ;
        wp:participants   <https://identifiers.org/ensembl/ENSBTAG00000017584> , <http://rdf.wikipathways.org/Pathway/WP3282_r140023/WP/Interaction/idfaee1523> ;
        wp:source         <https://identifiers.org/ensembl/ENSBTAG00000017584> ;
        wp:target         <http://rdf.wikipathways.org/Pathway/WP3282_r140023/WP/Interaction/idfaee1523> .

<https://identifiers.org/ensembl/ENSBTAG00000017584>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "PLCG1" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSBTAG00000017584> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSBTAG00000017584" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP3282_r140023/WP/Interaction/b2840> , <http://rdf.wikipathways.org/Pathway/WP3282_r140023/WP/Interaction/id85f10f7a> , <http://rdf.wikipathways.org/Pathway/WP3282_r140023/WP/Interaction/idb6262259> , <https://identifiers.org/wikipathways/WP3282_r140023> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSBTAG00000017584> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/281987> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/F1MYF9> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP3282_r140023/DataNode/f5b02> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/F1MYF9> ;
        foaf:page           <https://www.ensembl.org/id/ENSBTAG00000017584> .

<https://identifiers.org/hmdb/HMDB0010059>
        rdf:type            wp:Metabolite , wp:DataNode ;
        rdfs:label          "PIP2" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/CIKAEWLGOIVQBP-NXVRDOABSA-N> ;
        dc:identifier       <https://identifiers.org/hmdb/HMDB0010059> ;
        dc:source           "HMDB" ;
        dcterms:identifier  "HMDB0010059" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP3282_r140023/WP/Interaction/id9e7cce8> , <https://identifiers.org/wikipathways/WP3282_r140023> , <http://rdf.wikipathways.org/Pathway/WP3282_r140023/WP/Interaction/idac77b406> , <http://rdf.wikipathways.org/Pathway/WP3282_r140023/WP/Interaction/idfaee1523> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/24767936> ;
        wp:bdbHmdb          <https://identifiers.org/hmdb/HMDB0010059> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/CIKAEWLGOIVQBP-NXVRDOABSA-N> ;
        wp:bdbKeggCompound  <https://identifiers.org/kegg.compound/C00626> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID53480250> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q65681531> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP3282_r140023/DataNode/c6db8> , <http://rdf.wikipathways.org/Pathway/WP3282_r140023/DataNode/beb89> ;
        foaf:page           <http://www.hmdb.ca/metabolites/HMDB0010059> .

<http://rdf.wikipathways.org/Pathway/WP3282_r140023/WP/Interaction/id2fca9322>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP3282_r140023> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP3282_r140023/Interaction/id2fca9322> ;
        wp:participants   <https://identifiers.org/ensembl/ENSBTAG00000020294> , <https://identifiers.org/ensembl/ENSBTAG00000013170> ;
        wp:source         <https://identifiers.org/ensembl/ENSBTAG00000013170> ;
        wp:target         <https://identifiers.org/ensembl/ENSBTAG00000020294> .

<http://rdf.wikipathways.org/Pathway/WP3282_r140023/WP/Interaction/idaf4f9a86>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP3282_r140023> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP3282_r140023/Interaction/idaf4f9a86> ;
        wp:participants   <https://identifiers.org/ensembl/ENSBTAG00000016836> , <https://identifiers.org/hmdb/HMDB0010147> ;
        wp:source         <https://identifiers.org/hmdb/HMDB0010147> ;
        wp:target         <https://identifiers.org/ensembl/ENSBTAG00000016836> .

<https://identifiers.org/ensembl/ENSBTAG00000007256>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "DYRK2" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSBTAG00000007256> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSBTAG00000007256" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP3282_r140023> , <http://rdf.wikipathways.org/Pathway/WP3282_r140023/Complex/daadd> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSBTAG00000007256> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/104968453> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/E1BG90> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP3282_r140023/DataNode/a4c27> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/E1BG90> ;
        foaf:page           <https://www.ensembl.org/id/ENSBTAG00000007256> .

<https://identifiers.org/ensembl/ENSBTAG00000000306>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "ITK" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSBTAG00000000306> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSBTAG00000000306" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP3282_r140023/WP/Interaction/id85f10f7a> , <https://identifiers.org/wikipathways/WP3282_r140023> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSBTAG00000000306> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/522311> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A7Z039> , <https://identifiers.org/uniprot/A0A3Q1LNN2> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP3282_r140023/DataNode/b6ecd> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A3Q1LNN2> , <http://purl.uniprot.org/uniprot/A7Z039> ;
        foaf:page           <https://www.ensembl.org/id/ENSBTAG00000000306> .

<http://rdf.wikipathways.org/Pathway/WP3282_r140023/WP/Interaction/idb93be9d6>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP3282_r140023> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP3282_r140023/Interaction/idb93be9d6> ;
        wp:participants   <https://identifiers.org/ensembl/ENSBTAG00000017636> , <https://identifiers.org/hmdb/HMDB0010147> ;
        wp:source         <https://identifiers.org/hmdb/HMDB0010147> ;
        wp:target         <https://identifiers.org/ensembl/ENSBTAG00000017636> .

<https://identifiers.org/hmdb/HMDB0001059>
        rdf:type            wp:Metabolite , wp:DataNode ;
        rdfs:label          "IP3" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/CIPFCGZLFXVXBG-CNWJWELYSA-N> ;
        dc:identifier       <https://identifiers.org/hmdb/HMDB0001059> ;
        dc:source           "HMDB" ;
        dcterms:identifier  "HMDB0001059" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP3282_r140023/WP/Interaction/id95054879> , <http://rdf.wikipathways.org/Pathway/WP3282_r140023/WP/Interaction/idfaee1523> , <https://identifiers.org/wikipathways/WP3282_r140023> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:16783> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/17216047> ;
        wp:bdbHmdb          <https://identifiers.org/hmdb/HMDB0001059> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/CIPFCGZLFXVXBG-CNWJWELYSA-N> ;
        wp:bdbKeggCompound  <https://identifiers.org/kegg.compound/C01272> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID107758> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q27078094> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP3282_r140023/DataNode/d1518> ;
        foaf:page           <http://www.hmdb.ca/metabolites/HMDB0001059> .

<http://rdf.wikipathways.org/Pathway/WP3282_r140023/WP/Interaction/id54643aa6>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP3282_r140023> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP3282_r140023/Interaction/id54643aa6> ;
        wp:participants   <https://identifiers.org/ensembl/ENSBTAG00000017636> , <https://identifiers.org/ensembl/ENSBTAG00000016836> ;
        wp:source         <https://identifiers.org/ensembl/ENSBTAG00000016836> ;
        wp:target         <https://identifiers.org/ensembl/ENSBTAG00000017636> .

<http://rdf.wikipathways.org/Pathway/WP3282_r140023/ComplexBinding/daadd>
        rdf:type                       wp:ComplexBinding , wp:Interaction , wp:Binding ;
        dcterms:bibliographicCitation  <https://identifiers.org/pubmed/23483280> ;
        dcterms:isPartOf               <https://identifiers.org/wikipathways/WP3282_r140023> ;
        wp:isAbout                     <http://rdf.wikipathways.org/Pathway/WP3282_r140023/Group/daadd> ;
        wp:participants                <https://identifiers.org/ensembl/ENSBTAG00000048057> , <https://identifiers.org/ensembl/ENSBTAG00000007256> , <https://identifiers.org/ensembl/ENSBTAG00000001771> , <http://rdf.wikipathways.org/Pathway/WP3282_r140023/Complex/daadd> , <https://identifiers.org/ensembl/ENSBTAG00000018270> , <https://identifiers.org/ensembl/ENSBTAG00000005326> , <https://identifiers.org/ensembl/ENSBTAG00000020756> , <https://identifiers.org/ensembl/ENSBTAG00000044315> .

<https://identifiers.org/ensembl/ENSBTAG00000018270>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "NFATC2" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSBTAG00000018270> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSBTAG00000018270" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP3282_r140023/Complex/daadd> , <http://rdf.wikipathways.org/Pathway/WP3282_r140023/WP/Interaction/ida06fc4da> , <https://identifiers.org/wikipathways/WP3282_r140023> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSBTAG00000018270> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/530401> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A3Q1LMQ6> , <https://identifiers.org/uniprot/F1MGR9> , <https://identifiers.org/uniprot/A0A3Q1N525> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP3282_r140023/DataNode/ff620> , <http://rdf.wikipathways.org/Pathway/WP3282_r140023/DataNode/cc296> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A3Q1N525> , <http://purl.uniprot.org/uniprot/A0A3Q1LMQ6> , <http://purl.uniprot.org/uniprot/F1MGR9> ;
        foaf:page           <https://www.ensembl.org/id/ENSBTAG00000018270> .

<https://identifiers.org/ensembl/ENSBTAG00000001061>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "PRKCA" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSBTAG00000001061> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSBTAG00000001061" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP3282_r140023/WP/Interaction/ida1506fa6> , <https://identifiers.org/wikipathways/WP3282_r140023> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSBTAG00000001061> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/282001> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/F1MJX9> , <https://identifiers.org/uniprot/A0A3Q1MB84> , <https://identifiers.org/uniprot/A0A3Q1MQ80> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP3282_r140023/DataNode/b78e0> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A3Q1MB84> , <http://purl.uniprot.org/uniprot/F1MJX9> , <http://purl.uniprot.org/uniprot/A0A3Q1MQ80> ;
        foaf:page           <https://www.ensembl.org/id/ENSBTAG00000001061> .

<http://rdf.wikipathways.org/Pathway/WP3282_r140023/WP/Interaction/ida1506fa6>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP3282_r140023> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP3282_r140023/Interaction/ida1506fa6> ;
        wp:participants   <https://identifiers.org/ensembl/ENSBTAG00000001061> , <https://identifiers.org/hmdb/HMDB0007223> ;
        wp:source         <https://identifiers.org/hmdb/HMDB0007223> ;
        wp:target         <https://identifiers.org/ensembl/ENSBTAG00000001061> .

<https://identifiers.org/ensembl/ENSBTAG00000021141>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "CD8A" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSBTAG00000021141> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSBTAG00000021141" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP3282_r140023/Complex/b8142> , <https://identifiers.org/wikipathways/WP3282_r140023> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSBTAG00000021141> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/281060> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A7MAZ7> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP3282_r140023/DataNode/ed56f> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A7MAZ7> ;
        foaf:page           <https://www.ensembl.org/id/ENSBTAG00000021141> .

<https://identifiers.org/ensembl/ENSBTAG00000016683>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "NFKBIA" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSBTAG00000016683> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSBTAG00000016683" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP3282_r140023> , <http://rdf.wikipathways.org/Pathway/WP3282_r140023/WP/Interaction/id12ffba13> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSBTAG00000016683> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/282291> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q8WNW7> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP3282_r140023/DataNode/dd1b4> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q8WNW7> ;
        foaf:page           <https://www.ensembl.org/id/ENSBTAG00000016683> .

<https://identifiers.org/ensembl/ENSBTAG00000020294>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "PTPN6" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSBTAG00000020294> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSBTAG00000020294" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP3282_r140023/WP/Interaction/id6f3349d2> , <http://rdf.wikipathways.org/Pathway/WP3282_r140023/WP/Interaction/id2fca9322> , <https://identifiers.org/wikipathways/WP3282_r140023> , <http://rdf.wikipathways.org/Pathway/WP3282_r140023/WP/Interaction/id2489f199> , <http://rdf.wikipathways.org/Pathway/WP3282_r140023/WP/Interaction/idf1fab056> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSBTAG00000020294> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/512312> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A3Q1LU97> , <https://identifiers.org/uniprot/A0A3Q1M739> , <https://identifiers.org/uniprot/A5D980> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP3282_r140023/DataNode/d4781> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A3Q1LU97> , <http://purl.uniprot.org/uniprot/A5D980> , <http://purl.uniprot.org/uniprot/A0A3Q1M739> ;
        foaf:page           <https://www.ensembl.org/id/ENSBTAG00000020294> .

obo:NCBITaxon_9913  obo:NCIT_C179773  "9913" .

<https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=png&pwTitle=Pathway:WP3282&oldid=140023>
        rdf:type        foaf:Image ;
        dcterms:format  "image/png" .

<http://rdf.wikipathways.org/Pathway/WP3282_r140023/WP/Interaction/idac77b406>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP3282_r140023> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP3282_r140023/Interaction/idac77b406> ;
        wp:participants   <https://identifiers.org/hmdb/HMDB0007223> , <https://identifiers.org/hmdb/HMDB0010059> ;
        wp:source         <https://identifiers.org/hmdb/HMDB0010059> ;
        wp:target         <https://identifiers.org/hmdb/HMDB0007223> .

<http://rdf.wikipathways.org/Pathway/WP3282_r140023/WP/Interaction/id85f10f7a>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP3282_r140023> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP3282_r140023/Interaction/id85f10f7a> ;
        wp:participants   <https://identifiers.org/ensembl/ENSBTAG00000017584> , <https://identifiers.org/ensembl/ENSBTAG00000000306> ;
        wp:source         <https://identifiers.org/ensembl/ENSBTAG00000000306> ;
        wp:target         <https://identifiers.org/ensembl/ENSBTAG00000017584> .

<https://identifiers.org/ensembl/ENSBTAG00000044315>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "NRON" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSBTAG00000044315> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSBTAG00000044315" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP3282_r140023> , <http://rdf.wikipathways.org/Pathway/WP3282_r140023/Complex/daadd> ;
        dcterms:references  <https://identifiers.org/pubmed/24493213> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSBTAG00000044315> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/NRON> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP3282_r140023/DataNode/dea5f> ;
        foaf:page           <https://www.ensembl.org/id/ENSBTAG00000044315> .

<http://rdf.wikipathways.org/Pathway/WP3282_r140023/WP/Interaction/idff186ca1>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP3282_r140023> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP3282_r140023/Interaction/idff186ca1> ;
        wp:participants   <https://identifiers.org/ensembl/ENSBTAG00000021872> , <https://identifiers.org/hmdb/HMDB0007223> ;
        wp:source         <https://identifiers.org/hmdb/HMDB0007223> ;
        wp:target         <https://identifiers.org/ensembl/ENSBTAG00000021872> .

<http://rdf.wikipathways.org/Pathway/WP3282_r140023/WP/Interaction/id9e7cce8>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP3282_r140023> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP3282_r140023/Interaction/id9e7cce8> ;
        wp:participants   <https://identifiers.org/hmdb/HMDB0010147> , <https://identifiers.org/hmdb/HMDB0010059> ;
        wp:source         <https://identifiers.org/hmdb/HMDB0010059> ;
        wp:target         <https://identifiers.org/hmdb/HMDB0010147> .

<https://identifiers.org/ensembl/ENSBTAG00000021872>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "RASGRP1" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSBTAG00000021872> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSBTAG00000021872" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP3282_r140023/WP/Interaction/idff186ca1> , <https://identifiers.org/wikipathways/WP3282_r140023> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSBTAG00000021872> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/533125> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/E1BG59> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP3282_r140023/DataNode/beeba> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/E1BG59> ;
        foaf:page           <https://www.ensembl.org/id/ENSBTAG00000021872> .

<https://identifiers.org/ensembl/ENSBTAG00000011851>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "FYN" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSBTAG00000011851> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSBTAG00000011851" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP3282_r140023> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSBTAG00000011851> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/527263> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0JNB0> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP3282_r140023/DataNode/cd850> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0JNB0> ;
        foaf:page           <https://www.ensembl.org/id/ENSBTAG00000011851> .

<https://identifiers.org/hmdb/HMDB0000464>
        rdf:type            wp:DataNode , wp:Metabolite ;
        rdfs:label          "Ca²⁺" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/BHPQYMZQTOCNFJ-UHFFFAOYSA-N> ;
        dc:identifier       <https://identifiers.org/hmdb/HMDB0000464> ;
        dc:source           "HMDB" ;
        dcterms:identifier  "HMDB0000464" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP3282_r140023> , <http://rdf.wikipathways.org/Pathway/WP3282_r140023/WP/Interaction/id95054879> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:29108> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/266> ;
        wp:bdbHmdb          <https://identifiers.org/hmdb/HMDB0000464> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/BHPQYMZQTOCNFJ-UHFFFAOYSA-N> ;
        wp:bdbKeggCompound  <https://identifiers.org/kegg.compound/C00076> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID271> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q23905776> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP3282_r140023/DataNode/fea98> ;
        foaf:page           <http://www.hmdb.ca/metabolites/HMDB0000464> .

<https://identifiers.org/ensembl/ENSBTAG00000001771>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "DYRK1A" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSBTAG00000001771> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSBTAG00000001771" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP3282_r140023/Complex/daadd> , <https://identifiers.org/wikipathways/WP3282_r140023> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSBTAG00000001771> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/532989> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A3Q1LNU2> , <https://identifiers.org/uniprot/F1N2J2> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP3282_r140023/DataNode/d02ac> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/F1N2J2> , <http://purl.uniprot.org/uniprot/A0A3Q1LNU2> ;
        foaf:page           <https://www.ensembl.org/id/ENSBTAG00000001771> .

<http://rdf.wikipathways.org/Pathway/WP3282_r140023/WP/Interaction/ida06fc4da>
        rdf:type          wp:TranscriptionTranslation , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP3282_r140023> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP3282_r140023/Interaction/ida06fc4da> ;
        wp:participants   <https://identifiers.org/ensembl/ENSBTAG00000020883> , <https://identifiers.org/ensembl/ENSBTAG00000018270> ;
        wp:source         <https://identifiers.org/ensembl/ENSBTAG00000018270> ;
        wp:target         <https://identifiers.org/ensembl/ENSBTAG00000020883> .

<http://rdf.wikipathways.org/Pathway/WP3282_r140023/ComplexBinding/b8142>
        rdf:type          wp:ComplexBinding , wp:Binding , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP3282_r140023> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP3282_r140023/Group/b8142> ;
        wp:participants   <https://identifiers.org/ensembl/ENSBTAG00000021141> , <https://identifiers.org/ensembl/ENSBTAG00000008956> , <http://rdf.wikipathways.org/Pathway/WP3282_r140023/Complex/b8142> .

<https://identifiers.org/pubmed/23483280>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "23483280" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP3282_r140023/Complex/daadd> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/23483280> .

<https://identifiers.org/ensembl/ENSBTAG00000005326>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "CSNK1A1" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSBTAG00000005326> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSBTAG00000005326" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP3282_r140023> , <http://rdf.wikipathways.org/Pathway/WP3282_r140023/Complex/daadd> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSBTAG00000005326> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/282684> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q32LI4> , <https://identifiers.org/uniprot/A0A3Q1LK11> , <https://identifiers.org/uniprot/P67827> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP3282_r140023/DataNode/ee0e6> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q32LI4> , <http://purl.uniprot.org/uniprot/A0A3Q1LK11> , <http://purl.uniprot.org/uniprot/P67827> ;
        foaf:page           <https://www.ensembl.org/id/ENSBTAG00000005326> .

<http://rdf.wikipathways.org/Pathway/WP3282_r140023/WP/Interaction/id3874e5dc>
        rdf:type          wp:Inhibition , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP3282_r140023> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP3282_r140023/Interaction/id3874e5dc> ;
        wp:participants   <https://identifiers.org/ensembl/ENSBTAG00000009498> , <http://rdf.wikipathways.org/Pathway/WP3282_r140023/WP/Interaction/id9e7cce8> ;
        wp:source         <https://identifiers.org/ensembl/ENSBTAG00000009498> ;
        wp:target         <http://rdf.wikipathways.org/Pathway/WP3282_r140023/WP/Interaction/id9e7cce8> .

<https://identifiers.org/ensembl/ENSBTAG00000007445>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "CD28" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSBTAG00000007445> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSBTAG00000007445" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP3282_r140023> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSBTAG00000007445> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/281050> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/F1MXF4> , <https://identifiers.org/uniprot/A0A3Q1ND77> , <https://identifiers.org/uniprot/F1N4W3> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP3282_r140023/DataNode/ed30d> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/F1N4W3> , <http://purl.uniprot.org/uniprot/A0A3Q1ND77> , <http://purl.uniprot.org/uniprot/F1MXF4> ;
        foaf:page           <https://www.ensembl.org/id/ENSBTAG00000007445> .

<https://identifiers.org/pubmed/24493213>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "24493213" ;
        dcterms:isPartOf    <https://identifiers.org/ensembl/ENSBTAG00000044315> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/24493213> .

<https://identifiers.org/ensembl/ENSBTAG00000011543>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "PDCD1" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSBTAG00000011543> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSBTAG00000011543" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP3282_r140023/WP/Interaction/idf1fab056> , <https://identifiers.org/wikipathways/WP3282_r140023> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSBTAG00000011543> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/613842> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A3Q1LPI4> , <https://identifiers.org/uniprot/A0A3Q1N5P1> , <https://identifiers.org/uniprot/A0A3Q1MQR6> , <https://identifiers.org/uniprot/A4FV85> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP3282_r140023/DataNode/e282a> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A3Q1N5P1> , <http://purl.uniprot.org/uniprot/A0A3Q1MQR6> , <http://purl.uniprot.org/uniprot/A0A3Q1LPI4> , <http://purl.uniprot.org/uniprot/A4FV85> ;
        foaf:page           <https://www.ensembl.org/id/ENSBTAG00000011543> .

<https://identifiers.org/ensembl/ENSBTAG00000009565>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "RASA1" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSBTAG00000009565> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSBTAG00000009565" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP3282_r140023> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSBTAG00000009565> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/282032> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A3Q1M630> , <https://identifiers.org/uniprot/F1N7N8> , <https://identifiers.org/uniprot/A0A3Q1MNX0> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP3282_r140023/DataNode/f2b94> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A3Q1MNX0> , <http://purl.uniprot.org/uniprot/F1N7N8> , <http://purl.uniprot.org/uniprot/A0A3Q1M630> ;
        foaf:page           <https://www.ensembl.org/id/ENSBTAG00000009565> .

<http://rdf.wikipathways.org/Pathway/WP3282_r140023/Complex/daadd>
        rdf:type                       wp:DataNode , wp:Complex ;
        dcterms:bibliographicCitation  <https://identifiers.org/pubmed/23483280> ;
        dcterms:isPartOf               <https://identifiers.org/wikipathways/WP3282_r140023> ;
        dcterms:references             <https://identifiers.org/pubmed/23483280> ;
        wp:isAbout                     <http://rdf.wikipathways.org/Pathway/WP3282_r140023/Group/daadd> ;
        wp:participants                <https://identifiers.org/ensembl/ENSBTAG00000001771> , <https://identifiers.org/ensembl/ENSBTAG00000044315> , <https://identifiers.org/ensembl/ENSBTAG00000020756> , <https://identifiers.org/ensembl/ENSBTAG00000048057> , <https://identifiers.org/ensembl/ENSBTAG00000007256> , <https://identifiers.org/ensembl/ENSBTAG00000005326> , <https://identifiers.org/ensembl/ENSBTAG00000018270> .

<http://rdf.wikipathways.org/Pathway/WP3282_r140023/WP/Interaction/id2489f199>
        rdf:type          wp:Inhibition , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP3282_r140023> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP3282_r140023/Interaction/id2489f199> ;
        wp:participants   <https://identifiers.org/ensembl/ENSBTAG00000005892> , <https://identifiers.org/ensembl/ENSBTAG00000020294> ;
        wp:source         <https://identifiers.org/ensembl/ENSBTAG00000020294> ;
        wp:target         <https://identifiers.org/ensembl/ENSBTAG00000005892> .

<http://rdf.wikipathways.org/Pathway/WP3282_r140023/WP/Interaction/idb6262259>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP3282_r140023> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP3282_r140023/Interaction/idb6262259> ;
        wp:participants   <https://identifiers.org/ensembl/ENSBTAG00000017584> , <http://rdf.wikipathways.org/Pathway/WP3282_r140023/WP/Interaction/idac77b406> ;
        wp:source         <https://identifiers.org/ensembl/ENSBTAG00000017584> ;
        wp:target         <http://rdf.wikipathways.org/Pathway/WP3282_r140023/WP/Interaction/idac77b406> .

<https://identifiers.org/ensembl/ENSBTAG00000016005>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "PPP3CA" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSBTAG00000016005> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSBTAG00000016005" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP3282_r140023> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSBTAG00000016005> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/286852> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A3Q1MTH2> , <https://identifiers.org/uniprot/P48452> , <https://identifiers.org/uniprot/A0A3Q1M4S3> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP3282_r140023/DataNode/e95dc> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A3Q1M4S3> , <http://purl.uniprot.org/uniprot/P48452> , <http://purl.uniprot.org/uniprot/A0A3Q1MTH2> ;
        foaf:page           <https://www.ensembl.org/id/ENSBTAG00000016005> .

<https://identifiers.org/ensembl/ENSBTAG00000013170>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "CTLA4" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSBTAG00000013170> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSBTAG00000013170" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP3282_r140023> , <http://rdf.wikipathways.org/Pathway/WP3282_r140023/WP/Interaction/id2fca9322> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSBTAG00000013170> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/281732> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q28090> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP3282_r140023/DataNode/c2643> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q28090> ;
        foaf:page           <https://www.ensembl.org/id/ENSBTAG00000013170> .

<https://identifiers.org/hmdb/HMDB0007223>
        rdf:type            wp:Metabolite , wp:DataNode ;
        rdfs:label          "DAG" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/MRYGMFRXGCUEJC-WRDQRZSUSA-N> ;
        dc:identifier       <https://identifiers.org/hmdb/HMDB0007223> ;
        dc:source           "HMDB" ;
        dcterms:identifier  "HMDB0007223" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP3282_r140023/WP/Interaction/idff186ca1> , <http://rdf.wikipathways.org/Pathway/WP3282_r140023/WP/Interaction/idac77b406> , <http://rdf.wikipathways.org/Pathway/WP3282_r140023/WP/Interaction/ida1506fa6> , <https://identifiers.org/wikipathways/WP3282_r140023> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:89224> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/7822697> ;
        wp:bdbHmdb          <https://identifiers.org/hmdb/HMDB0007223> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/MRYGMFRXGCUEJC-WRDQRZSUSA-N> ;
        wp:bdbLipidMaps     <https://identifiers.org/lipidmaps/LMGL02010081> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID9543747> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q27161410> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP3282_r140023/DataNode/ab4fe> ;
        owl:sameAs          <https://swisslipids.org/rdf/SLM_000122258> , <https://www.lipidmaps.org/rdf/LMGL02010081> ;
        foaf:page           <http://www.hmdb.ca/metabolites/HMDB0007223> .

<https://identifiers.org/wikipathways/WP3282>
        pav:hasVersion  <https://identifiers.org/wikipathways/WP3282_r140023> .

<https://identifiers.org/wikipathways/WP3282_r140023>
        rdf:type               skos:Collection , wp:Pathway ;
        dc:identifier          <https://identifiers.org/wikipathways/WP3282> ;
        dc:source              "WikiPathways" ;
        dc:title               "T cell receptor and co-stimulatory signaling"@en ;
        dcterms:description    "The activation and translocation of transcription factors NFAT, AP-1 and NF-kappa-B via the co-stimulatory signaling cascade triggered by MHC peptide, B7 proteins and PD-L1. The activation of NFAT involves a Ca²⁺/calcineurin disruption of a massive RNA-protein complex prior to its translocation into the nucleus and ultimate transcription factor activity." ;
        dcterms:identifier     "WP3282" ;
        cito:cites             <https://identifiers.org/pubmed/23483280> , <https://identifiers.org/pubmed/24493213> ;
        wp:isAbout             <http://rdf.wikipathways.org/Pathway/WP3282_r140023> ;
        wp:ontologyTag         obo:PW_0000317 , wp:Curation:AnalysisCollection , obo:PW_0000814 , wp:Curation:Homology_Converted , obo:PW_0000315 ;
        wp:organism            obo:NCBITaxon_9913 ;
        wp:organismName        "Bos taurus" ;
        wp:pathwayOntologyTag  obo:PW_0000814 , obo:PW_0000317 , obo:PW_0000315 ;
        foaf:img               <https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=svg&pwTitle=Pathway:WP3282&oldid=140023> , <https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=png&pwTitle=Pathway:WP3282&oldid=140023> ;
        foaf:page              <http://www.wikipathways.org/instance/WP3282_r140023> .

<https://identifiers.org/hmdb/HMDB0010147>
        rdf:type            wp:Metabolite , wp:DataNode ;
        rdfs:label          "PIP3" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/ZSZXYWFCIKKZBT-LBWXJXETSA-N> ;
        dc:identifier       <https://identifiers.org/hmdb/HMDB0010147> ;
        dc:source           "HMDB" ;
        dcterms:identifier  "HMDB0010147" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP3282_r140023/WP/Interaction/idb93be9d6> , <http://rdf.wikipathways.org/Pathway/WP3282_r140023/WP/Interaction/id9e7cce8> , <http://rdf.wikipathways.org/Pathway/WP3282_r140023/WP/Interaction/idaf4f9a86> , <https://identifiers.org/wikipathways/WP3282_r140023> , <http://rdf.wikipathways.org/Pathway/WP3282_r140023/WP/Interaction/id6f3349d2> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:84244> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/24768024> ;
        wp:bdbHmdb          <https://identifiers.org/hmdb/HMDB0010147> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/ZSZXYWFCIKKZBT-LBWXJXETSA-N> ;
        wp:bdbKeggCompound  <https://identifiers.org/kegg.compound/C00626> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q27157614> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP3282_r140023/DataNode/b8443> ;
        foaf:page           <http://www.hmdb.ca/metabolites/HMDB0010147> .

<https://identifiers.org/ensembl/ENSBTAG00000020756>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "GSK3A" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSBTAG00000020756> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSBTAG00000020756" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP3282_r140023> , <http://rdf.wikipathways.org/Pathway/WP3282_r140023/Complex/daadd> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSBTAG00000020756> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/536561> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A3S5ZPG7> , <https://identifiers.org/uniprot/A0A3Q1LJI4> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP3282_r140023/DataNode/f3f11> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A3S5ZPG7> , <http://purl.uniprot.org/uniprot/A0A3Q1LJI4> ;
        foaf:page           <https://www.ensembl.org/id/ENSBTAG00000020756> .

<http://rdf.wikipathways.org/Pathway/WP3282_r140023/WP/Interaction/idfaee1523>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP3282_r140023> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP3282_r140023/Interaction/idfaee1523> ;
        wp:participants   <https://identifiers.org/hmdb/HMDB0001059> , <https://identifiers.org/hmdb/HMDB0010059> ;
        wp:source         <https://identifiers.org/hmdb/HMDB0010059> ;
        wp:target         <https://identifiers.org/hmdb/HMDB0001059> .

<http://rdf.wikipathways.org/Pathway/WP3282_r140023/Complex/b8142>
        rdf:type          wp:Complex , wp:DataNode ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP3282_r140023> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP3282_r140023/Group/b8142> ;
        wp:participants   <https://identifiers.org/ensembl/ENSBTAG00000021141> , <https://identifiers.org/ensembl/ENSBTAG00000008956> .

<http://rdf.wikipathways.org/Pathway/WP3282_r140023/WP/Interaction/id95054879>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP3282_r140023> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP3282_r140023/Interaction/id95054879> ;
        wp:participants   <https://identifiers.org/hmdb/HMDB0000464> , <https://identifiers.org/hmdb/HMDB0001059> ;
        wp:source         <https://identifiers.org/hmdb/HMDB0001059> ;
        wp:target         <https://identifiers.org/hmdb/HMDB0000464> .

<https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=svg&pwTitle=Pathway:WP3282&oldid=140023>
        rdf:type        foaf:Image ;
        dcterms:format  "image/svg+xml" .

<https://identifiers.org/ensembl/ENSBTAG00000009498>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "PTEN" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSBTAG00000009498> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSBTAG00000009498" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP3282_r140023/WP/Interaction/id3874e5dc> , <https://identifiers.org/wikipathways/WP3282_r140023> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSBTAG00000009498> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/540786> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A3Q1MXQ5> , <https://identifiers.org/uniprot/F1MDX9> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP3282_r140023/DataNode/e9f05> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A3Q1MXQ5> , <http://purl.uniprot.org/uniprot/F1MDX9> ;
        foaf:page           <https://www.ensembl.org/id/ENSBTAG00000009498> .

<http://rdf.wikipathways.org/Pathway/WP3282_r140023/WP/Interaction/iddf233a60>
        rdf:type          wp:TranscriptionTranslation , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP3282_r140023> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP3282_r140023/Interaction/iddf233a60> ;
        wp:participants   <https://identifiers.org/ensembl/ENSBTAG00000020883> , <https://identifiers.org/ensembl/ENSBTAG00000020270> ;
        wp:source         <https://identifiers.org/ensembl/ENSBTAG00000020270> ;
        wp:target         <https://identifiers.org/ensembl/ENSBTAG00000020883> .

<https://identifiers.org/ensembl/ENSBTAG00000020270>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "NFKB1" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSBTAG00000020270> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSBTAG00000020270" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP3282_r140023> , <http://rdf.wikipathways.org/Pathway/WP3282_r140023/WP/Interaction/iddf233a60> , <http://rdf.wikipathways.org/Pathway/WP3282_r140023/WP/Interaction/id12ffba13> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSBTAG00000020270> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/616115> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/F1MKW9> , <https://identifiers.org/uniprot/A0A3Q1LGS4> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP3282_r140023/DataNode/d965c> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/F1MKW9> , <http://purl.uniprot.org/uniprot/A0A3Q1LGS4> ;
        foaf:page           <https://www.ensembl.org/id/ENSBTAG00000020270> .

<https://identifiers.org/ensembl/ENSBTAG00000017636>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "AKT1" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSBTAG00000017636> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSBTAG00000017636" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP3282_r140023> , <http://rdf.wikipathways.org/Pathway/WP3282_r140023/WP/Interaction/id54643aa6> , <http://rdf.wikipathways.org/Pathway/WP3282_r140023/WP/Interaction/idb93be9d6> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSBTAG00000017636> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/280991> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A3Q1MJ77> , <https://identifiers.org/uniprot/G3X7B5> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP3282_r140023/DataNode/c5e7e> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A3Q1MJ77> , <http://purl.uniprot.org/uniprot/G3X7B5> ;
        foaf:page           <https://www.ensembl.org/id/ENSBTAG00000017636> .
