@prefix biopax:  <http://www.biopax.org/release/biopax-level3.owl#> .
@prefix cito:    <http://purl.org/spar/cito/> .
@prefix dc:      <http://purl.org/dc/elements/1.1/> .
@prefix dcterms: <http://purl.org/dc/terms/> .
@prefix foaf:    <http://xmlns.com/foaf/0.1/> .
@prefix freq:    <http://purl.org/cld/freq/> .
@prefix gpml:    <http://vocabularies.wikipathways.org/gpml#> .
@prefix obo:     <http://purl.obolibrary.org/obo/> .
@prefix owl:     <http://www.w3.org/2002/07/owl#> .
@prefix pav:     <http://purl.org/pav/> .
@prefix prov:    <http://www.w3.org/ns/prov#> .
@prefix rdf:     <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix rdfs:    <http://www.w3.org/2000/01/rdf-schema#> .
@prefix skos:    <http://www.w3.org/2004/02/skos/core#> .
@prefix void:    <http://rdfs.org/ns/void#> .
@prefix wp:      <http://vocabularies.wikipathways.org/wp#> .
@prefix wprdf:   <http://rdf.wikipathways.org/> .
@prefix xsd:     <http://www.w3.org/2001/XMLSchema#> .

<http://rdf.wikipathways.org/Pathway/WP5509_r140915/WP/Interaction/a743f>
        rdf:type          wp:Inhibition , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP5509_r140915> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP5509_r140915/Interaction/a743f> ;
        wp:participants   <https://identifiers.org/wikipathways/WP2596> , <https://identifiers.org/ensembl/ENSG00000159224> ;
        wp:source         <https://identifiers.org/ensembl/ENSG00000159224> ;
        wp:target         <https://identifiers.org/wikipathways/WP2596> .

<https://identifiers.org/ensembl/ENSG00000115263>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "GCG" , "GLP-1" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000115263> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000115263" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP5509_r140915/WP/Interaction/dfec0> , <http://rdf.wikipathways.org/Pathway/WP5509_r140915/WP/Interaction/e57cb> , <http://rdf.wikipathways.org/Pathway/WP5509_r140915/WP/Interaction/da576> , <https://identifiers.org/wikipathways/WP5509_r140915> , <http://rdf.wikipathways.org/Pathway/WP5509_r140915/WP/Interaction/e35d5> , <http://rdf.wikipathways.org/Pathway/WP5509_r140915/WP/Interaction/id1483a631> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000115263> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/2641> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/GCG> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/P01275> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q14821391> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5509_r140915/DataNode/c5a6d> , <http://rdf.wikipathways.org/Pathway/WP5509_r140915/DataNode/a675d> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P01275> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000115263> .

<https://identifiers.org/wikipathways/WP2596>
        rdf:type            wp:DataNode , wp:Pathway ;
        rdfs:label          "Gastric acid secretion" ;
        dc:identifier       <https://identifiers.org/wikipathways/WP2596> ;
        dc:source           "WikiPathways" ;
        dcterms:identifier  "WP2596" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP5509_r140915/WP/Interaction/a743f> , <https://identifiers.org/wikipathways/WP5509_r140915> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5509_r140915/DataNode/c952c> ;
        foaf:page           <https://www.wikipathways.org/instance/WP2596> .

<http://rdf.wikipathways.org/Pathway/WP5509_r140915/WP/Interaction/da576>
        rdf:type          wp:Stimulation , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP5509_r140915> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP5509_r140915/Interaction/da576> ;
        wp:participants   <https://identifiers.org/chebi/CHEBI:5931> , <https://identifiers.org/ensembl/ENSG00000115263> ;
        wp:source         <https://identifiers.org/ensembl/ENSG00000115263> ;
        wp:target         <https://identifiers.org/chebi/CHEBI:5931> .

<https://identifiers.org/chebi/CHEBI:5931>
        rdf:type            wp:DataNode , wp:Metabolite ;
        rdfs:label          "Insulin" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/PBGKTOXHQIOBKM-FHFVDXKLSA-N> ;
        dc:identifier       <https://identifiers.org/chebi/CHEBI:5931> ;
        dc:source           "ChEBI" ;
        dcterms:identifier  "CHEBI:5931" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP5509_r140915/WP/Interaction/d14fb> , <https://identifiers.org/wikipathways/WP5509_r140915> , <http://rdf.wikipathways.org/Pathway/WP5509_r140915/WP/Interaction/da576> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:5931> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/17286481> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/PBGKTOXHQIOBKM-FHFVDXKLSA-N> ;
        wp:bdbKeggCompound  <https://identifiers.org/kegg.compound/C00723> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID168324652> , <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID118984375> , <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID16129672> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q50265665> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5509_r140915/DataNode/d9439> ;
        foaf:page           <https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:5931> .

<https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=png&pwTitle=Pathway:WP5509&oldid=140915>
        rdf:type        foaf:Image ;
        dcterms:format  "image/png" .

<http://rdf.wikipathways.org/Pathway/WP5509_r140915/WP/Interaction/id1483a631>
        rdf:type          wp:TranscriptionTranslation , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP5509_r140915> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP5509_r140915/Interaction/id1483a631> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000115263> ;
        wp:source         <https://identifiers.org/ensembl/ENSG00000115263> ;
        wp:target         <https://identifiers.org/ensembl/ENSG00000115263> .

<http://rdf.wikipathways.org/Pathway/WP5509_r140915/WP/Interaction/dfec0>
        rdf:type          wp:Inhibition , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP5509_r140915> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP5509_r140915/Interaction/dfec0> ;
        wp:participants   <https://identifiers.org/wikipathways/WP254> , <https://identifiers.org/ensembl/ENSG00000115263> ;
        wp:source         <https://identifiers.org/ensembl/ENSG00000115263> ;
        wp:target         <https://identifiers.org/wikipathways/WP254> .

<http://rdf.wikipathways.org/Pathway/WP5509_r140915/WP/Interaction/d14fb>
        rdf:type          wp:Stimulation , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP5509_r140915> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP5509_r140915/Interaction/d14fb> ;
        wp:participants   <https://identifiers.org/chebi/CHEBI:5931> , <https://identifiers.org/ensembl/ENSG00000159224> ;
        wp:source         <https://identifiers.org/ensembl/ENSG00000159224> ;
        wp:target         <https://identifiers.org/chebi/CHEBI:5931> .

<https://identifiers.org/chebi/CHEBI:5391>
        rdf:type            wp:Metabolite , wp:DataNode ;
        rdfs:label          "Glucagon" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/MASNOZXLGMXCHN-ZLPAWPGGSA-N> ;
        dc:identifier       <https://identifiers.org/chebi/CHEBI:5391> ;
        dc:source           "ChEBI" ;
        dcterms:identifier  "CHEBI:5391" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP5509_r140915/WP/Interaction/e57cb> , <https://identifiers.org/wikipathways/WP5509_r140915> , <http://rdf.wikipathways.org/Pathway/WP5509_r140915/WP/Interaction/b3446> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:5391> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/MASNOZXLGMXCHN-ZLPAWPGGSA-N> ;
        wp:bdbKeggCompound  <https://identifiers.org/kegg.compound/C01501> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID44278361> , <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID102331734> , <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID16132283> , <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID16133817> , <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID16186314> , <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID77077981> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q72480372> , <http://www.wikidata.org/entity/Q170617> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5509_r140915/DataNode/f4cb9> ;
        foaf:page           <https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:5391> .

<https://identifiers.org/ensembl/ENSG00000159224>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "GIP" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000159224> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000159224" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP5509_r140915/WP/Interaction/d14fb> , <http://rdf.wikipathways.org/Pathway/WP5509_r140915/WP/Interaction/ddc76> , <http://rdf.wikipathways.org/Pathway/WP5509_r140915/WP/Interaction/b3446> , <http://rdf.wikipathways.org/Pathway/WP5509_r140915/WP/Interaction/a743f> , <https://identifiers.org/wikipathways/WP5509_r140915> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000159224> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/2695> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/GIP> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/P09681> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q419977> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5509_r140915/DataNode/b36a0> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P09681> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000159224> .

<https://identifiers.org/wikipathways/WP5509>
        pav:hasVersion  <https://identifiers.org/wikipathways/WP5509_r140915> .

<https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=svg&pwTitle=Pathway:WP5509&oldid=140915>
        rdf:type        foaf:Image ;
        dcterms:format  "image/svg+xml" .

<http://rdf.wikipathways.org/Pathway/WP5509_r140915/WP/Interaction/e57cb>
        rdf:type          wp:Inhibition , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP5509_r140915> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP5509_r140915/Interaction/e57cb> ;
        wp:participants   <https://identifiers.org/chebi/CHEBI:5391> , <https://identifiers.org/ensembl/ENSG00000115263> ;
        wp:source         <https://identifiers.org/ensembl/ENSG00000115263> ;
        wp:target         <https://identifiers.org/chebi/CHEBI:5391> .

<http://rdf.wikipathways.org/Pathway/WP5509_r140915/WP/Interaction/b3446>
        rdf:type          wp:Stimulation , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP5509_r140915> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP5509_r140915/Interaction/b3446> ;
        wp:participants   <https://identifiers.org/chebi/CHEBI:5391> , <https://identifiers.org/ensembl/ENSG00000159224> ;
        wp:source         <https://identifiers.org/ensembl/ENSG00000159224> ;
        wp:target         <https://identifiers.org/chebi/CHEBI:5391> .

<http://rdf.wikipathways.org/Pathway/WP5509_r140915/WP/Interaction/ddc76>
        rdf:type          wp:Inhibition , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP5509_r140915> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP5509_r140915/Interaction/ddc76> ;
        wp:participants   <https://identifiers.org/wikipathways/WP254> , <https://identifiers.org/ensembl/ENSG00000159224> ;
        wp:source         <https://identifiers.org/ensembl/ENSG00000159224> ;
        wp:target         <https://identifiers.org/wikipathways/WP254> .

<http://rdf.wikipathways.org/Pathway/WP5509_r140915/WP/Interaction/e35d5>
        rdf:type          wp:Stimulation , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP5509_r140915> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP5509_r140915/Interaction/e35d5> ;
        wp:participants   <https://identifiers.org/wikipathways/WP5445> , <https://identifiers.org/ensembl/ENSG00000115263> ;
        wp:source         <https://identifiers.org/ensembl/ENSG00000115263> ;
        wp:target         <https://identifiers.org/wikipathways/WP5445> .

obo:NCBITaxon_9606  obo:NCIT_C179773  "9606" .

<https://identifiers.org/wikipathways/WP254>
        rdf:type            wp:DataNode , wp:Pathway ;
        rdfs:label          "Apoptosis" ;
        dc:identifier       <https://identifiers.org/wikipathways/WP254> ;
        dc:source           "WikiPathways" ;
        dcterms:identifier  "WP254" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP5509_r140915/WP/Interaction/ddc76> , <https://identifiers.org/wikipathways/WP5509_r140915> , <http://rdf.wikipathways.org/Pathway/WP5509_r140915/WP/Interaction/dfec0> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5509_r140915/DataNode/b53e9> ;
        foaf:page           <https://www.wikipathways.org/instance/WP254> .

<https://identifiers.org/pubmed/24843404>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "24843404" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP5509_r140915> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/24843404> .

<https://identifiers.org/wikipathways/WP5509_r140915>
        rdf:type                skos:Collection , wp:Pathway ;
        dc:identifier           <https://identifiers.org/wikipathways/WP5509> ;
        dc:source               "WikiPathways" ;
        dc:title                "GIP and GLP-1 function by tissue"@en ;
        dcterms:description     "Functions of GIP and GLP-1, two agonists of which are found in the weight-loss drug tirzepatide (a.k.a. Mounjaro).\n\n\"Pancreatic and exopancreatic function of glucose‐dependent insulinotropic polypepide (GIP) and glucagon‐like peptide (GLP)‐1. GIP acts directly on the endocrine pancreas, bone, fat, gastrointestinal (GI) tract and brain. GLP‐1 acts directly on the endocrine pancreas, gastrointestinal tract, heart and brain.\"  From Figure 2 in https://pmc.ncbi.nlm.nih.gov/articles/PMC4020673/." ;
        dcterms:identifier      "WP5509" ;
        dcterms:references      <https://identifiers.org/pubmed/24843404> ;
        cito:cites              <https://identifiers.org/pubmed/24843404> ;
        wp:cellTypeOntologyTag  obo:CL_0000540 , obo:CL_0000169 , obo:CL_0002563 ;
        wp:isAbout              <http://rdf.wikipathways.org/Pathway/WP5509_r140915> ;
        wp:ontologyTag          obo:CL_0000169 , wp:Curation:AnalysisCollection , obo:CL_0000540 , obo:CL_0002563 ;
        wp:organism             obo:NCBITaxon_9606 ;
        wp:organismName         "Homo sapiens" ;
        foaf:img                <https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=png&pwTitle=Pathway:WP5509&oldid=140915> , <https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=svg&pwTitle=Pathway:WP5509&oldid=140915> ;
        foaf:page               <http://www.wikipathways.org/instance/WP5509_r140915> .

<https://identifiers.org/wikipathways/WP5445>
        rdf:type            wp:DataNode , wp:Pathway ;
        rdfs:label          "Hunger" ;
        dc:identifier       <https://identifiers.org/wikipathways/WP5445> ;
        dc:source           "WikiPathways" ;
        dcterms:identifier  "WP5445" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP5509_r140915> , <http://rdf.wikipathways.org/Pathway/WP5509_r140915/WP/Interaction/e35d5> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5509_r140915/DataNode/b1cee> ;
        foaf:page           <https://www.wikipathways.org/instance/WP5445> .
