@prefix biopax:  <http://www.biopax.org/release/biopax-level3.owl#> .
@prefix cito:    <http://purl.org/spar/cito/> .
@prefix dc:      <http://purl.org/dc/elements/1.1/> .
@prefix dcterms: <http://purl.org/dc/terms/> .
@prefix foaf:    <http://xmlns.com/foaf/0.1/> .
@prefix freq:    <http://purl.org/cld/freq/> .
@prefix gpml:    <http://vocabularies.wikipathways.org/gpml#> .
@prefix obo:     <http://purl.obolibrary.org/obo/> .
@prefix owl:     <http://www.w3.org/2002/07/owl#> .
@prefix pav:     <http://purl.org/pav/> .
@prefix prov:    <http://www.w3.org/ns/prov#> .
@prefix rdf:     <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix rdfs:    <http://www.w3.org/2000/01/rdf-schema#> .
@prefix skos:    <http://www.w3.org/2004/02/skos/core#> .
@prefix void:    <http://rdfs.org/ns/void#> .
@prefix wp:      <http://vocabularies.wikipathways.org/wp#> .
@prefix wprdf:   <http://rdf.wikipathways.org/> .
@prefix xsd:     <http://www.w3.org/2001/XMLSchema#> .

<https://identifiers.org/cas/14875-96-8>
        rdf:type            wp:Metabolite , wp:DataNode ;
        rdfs:label          "protoheme" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/KABFMIBPWCXCRK-RGGAHWMASA-N> ;
        dc:identifier       <https://identifiers.org/cas/14875-96-8> ;
        dc:source           "CAS" ;
        dcterms:identifier  "14875-96-8" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP561_r142374/WP/Interaction/a6b7b> , <https://identifiers.org/wikipathways/WP561_r142374> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:26355> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/16739950> ;
        wp:bdbHmdb          <https://identifiers.org/hmdb/HMDB0003178> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/KABFMIBPWCXCRK-RGGAHWMASA-L> ;
        wp:bdbKeggCompound  <https://identifiers.org/kegg.compound/C00032> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID444098> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q620084> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP561_r142374/DataNode/f4c> ;
        foaf:page           <https://commonchemistry.cas.org/detail?cas_rn=14875-96-8> .

<https://identifiers.org/chebi/CHEBI:57307>
        rdf:type            wp:DataNode , wp:Metabolite ;
        rdfs:label          "protoporphyrinogen IX" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/UHSGPDMIQQYNAX-UHFFFAOYSA-N> ;
        dc:identifier       <https://identifiers.org/chebi/CHEBI:57307> ;
        dc:source           "ChEBI" ;
        dcterms:identifier  "CHEBI:57307" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP561_r142374/WP/Interaction/e81fa> , <https://identifiers.org/wikipathways/WP561_r142374> , <http://rdf.wikipathways.org/Pathway/WP561_r142374/WP/Interaction/e2071> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:57307> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/20171538> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/UHSGPDMIQQYNAX-UHFFFAOYSA-L> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID20849104> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q27124410> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP561_r142374/DataNode/a5906> ;
        foaf:page           <https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:57307> .

<http://rdf.wikipathways.org/Pathway/WP561_r142374/WP/Interaction/eb348>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP561_r142374> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP561_r142374/Interaction/fa447> , <http://rdf.wikipathways.org/Pathway/WP561_r142374/Interaction/eb348> ;
        wp:participants   <https://identifiers.org/cas/1976-85-8> , <https://identifiers.org/chebi/CHEBI:16645> , <https://identifiers.org/hmdb/HMDB0002111> ;
        wp:source         <https://identifiers.org/chebi/CHEBI:16645> ;
        wp:target         <https://identifiers.org/cas/1976-85-8> , <https://identifiers.org/hmdb/HMDB0002111> .

<http://rdf.wikipathways.org/Pathway/WP561_r142374/WP/Interaction/b0495>
        rdf:type          wp:Interaction , wp:DirectedInteraction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP561_r142374> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP561_r142374/Interaction/b0495> , <http://rdf.wikipathways.org/Pathway/WP561_r142374/Interaction/cc7d5> ;
        wp:participants   <https://identifiers.org/cas/1976-85-8> , <https://identifiers.org/cas/2624-63-7> , <https://identifiers.org/hmdb/HMDB0001967> ;
        wp:source         <https://identifiers.org/cas/1976-85-8> ;
        wp:target         <https://identifiers.org/cas/2624-63-7> , <https://identifiers.org/hmdb/HMDB0001967> .

<http://rdf.wikipathways.org/Pathway/WP561_r142374/WP/Interaction/d64e8>
        rdf:type          wp:Interaction , wp:DirectedInteraction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP561_r142374> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP561_r142374/Interaction/a2adf> , <http://rdf.wikipathways.org/Pathway/WP561_r142374/Interaction/d64e8> , <http://rdf.wikipathways.org/Pathway/WP561_r142374/Interaction/def97> ;
        wp:participants   <https://identifiers.org/cas/487-90-1> , <https://identifiers.org/chemspider/10447539> , <https://identifiers.org/hmdb/HMDB0002111> ;
        wp:source         <https://identifiers.org/chemspider/10447539> ;
        wp:target         <https://identifiers.org/cas/487-90-1> , <https://identifiers.org/hmdb/HMDB0002111> .

<https://identifiers.org/hmdb/HMDB0002111>
        rdf:type            wp:Metabolite , wp:DataNode ;
        rdfs:label          "H₂O" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/XLYOFNOQVPJJNP-UHFFFAOYSA-N> ;
        dc:identifier       <https://identifiers.org/hmdb/HMDB0002111> ;
        dc:source           "HMDB" ;
        dcterms:identifier  "HMDB0002111" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP561_r142374> , <http://rdf.wikipathways.org/Pathway/WP561_r142374/WP/Interaction/d64e8> , <http://rdf.wikipathways.org/Pathway/WP561_r142374/WP/Interaction/eb348> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:15377> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/937> ;
        wp:bdbHmdb          <https://identifiers.org/hmdb/HMDB0002111> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/XLYOFNOQVPJJNP-UHFFFAOYSA-N> ;
        wp:bdbKeggCompound  <https://identifiers.org/kegg.compound/C00001> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID962> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q283> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP561_r142374/DataNode/d789f> , <http://rdf.wikipathways.org/Pathway/WP561_r142374/DataNode/efc67> , <http://rdf.wikipathways.org/Pathway/WP561_r142374/DataNode/dfd99> ;
        foaf:page           <http://www.hmdb.ca/metabolites/HMDB0002111> .

<http://rdf.wikipathways.org/Pathway/WP561_r142374/WP/Interaction/bacc2>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP561_r142374> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP561_r142374/Interaction/bacc2> , <http://rdf.wikipathways.org/Pathway/WP561_r142374/Interaction/bcfc0> , <http://rdf.wikipathways.org/Pathway/WP561_r142374/Interaction/c00a3> ;
        wp:participants   <https://identifiers.org/cas/487-90-1> , <https://identifiers.org/chebi/CHEBI:16645> , <https://identifiers.org/hmdb/HMDB0000051> ;
        wp:source         <https://identifiers.org/cas/487-90-1> ;
        wp:target         <https://identifiers.org/hmdb/HMDB0000051> , <https://identifiers.org/chebi/CHEBI:16645> .

<https://identifiers.org/cas/487-90-1>
        rdf:type            wp:DataNode , wp:Metabolite ;
        rdfs:label          "porphobilinogen" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/QSHWIQZFGQKFMA-UHFFFAOYSA-N> ;
        dc:identifier       <https://identifiers.org/cas/487-90-1> ;
        dc:source           "CAS" ;
        dcterms:identifier  "487-90-1" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP561_r142374> , <http://rdf.wikipathways.org/Pathway/WP561_r142374/WP/Interaction/d64e8> , <http://rdf.wikipathways.org/Pathway/WP561_r142374/WP/Interaction/bacc2> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:17381> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/995> ;
        wp:bdbHmdb          <https://identifiers.org/hmdb/HMDB0000245> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/QSHWIQZFGQKFMA-UHFFFAOYSA-N> ;
        wp:bdbKeggCompound  <https://identifiers.org/kegg.compound/C00931> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID1021> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q421178> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP561_r142374/DataNode/ad4> ;
        foaf:page           <https://commonchemistry.cas.org/detail?cas_rn=487-90-1> .

<https://identifiers.org/ncbigene/1371>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "CPOX" ;
        dc:identifier       <https://identifiers.org/ncbigene/1371> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "1371" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP561_r142374/WP/Interaction/ddd8c> , <https://identifiers.org/wikipathways/WP561_r142374> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000080819> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/1371> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/CPOX> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/D6RER6> , <https://identifiers.org/uniprot/P36551> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP561_r142374/DataNode/d76> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P36551> , <http://purl.uniprot.org/uniprot/D6RER6> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/1371> .

<https://identifiers.org/ncbigene/2235>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "FECH" ;
        dc:identifier       <https://identifiers.org/ncbigene/2235> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "2235" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP561_r142374> , <http://rdf.wikipathways.org/Pathway/WP561_r142374/WP/Interaction/e30ff> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000066926> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/2235> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/FECH> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/K7EJM8> , <https://identifiers.org/uniprot/K7EJX5> , <https://identifiers.org/uniprot/P22830> , <https://identifiers.org/uniprot/A0A499FJN5> , <https://identifiers.org/uniprot/K7ELX4> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP561_r142374/DataNode/c3a> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P22830> , <http://purl.uniprot.org/uniprot/K7ELX4> , <http://purl.uniprot.org/uniprot/K7EJM8> , <http://purl.uniprot.org/uniprot/K7EJX5> , <http://purl.uniprot.org/uniprot/A0A499FJN5> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/2235> .

<https://identifiers.org/hmdb/HMDB0000245>
        rdf:type            wp:DataNode , wp:Metabolite ;
        rdfs:label          "Porphobilinogen" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/QSHWIQZFGQKFMA-UHFFFAOYSA-N> ;
        dc:identifier       <https://identifiers.org/hmdb/HMDB0000245> ;
        dc:source           "HMDB" ;
        dcterms:identifier  "HMDB0000245" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP561_r142374> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:17381> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/995> ;
        wp:bdbHmdb          <https://identifiers.org/hmdb/HMDB0000245> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/QSHWIQZFGQKFMA-UHFFFAOYSA-N> ;
        wp:bdbKeggCompound  <https://identifiers.org/kegg.compound/C00931> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID1021> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q421178> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP561_r142374/DataNode/da9f5> ;
        foaf:page           <http://www.hmdb.ca/metabolites/HMDB0000245> .

obo:NCBITaxon_9606  obo:NCIT_C179773  "9606" .

<https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=png&pwTitle=Pathway:WP561&oldid=142374>
        rdf:type        foaf:Image ;
        dcterms:format  "image/png" .

<https://identifiers.org/hmdb/HMDB0001423>
        rdf:type            wp:Metabolite , wp:DataNode ;
        rdfs:label          "CoA" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/RGJOEKWQDUBAIZ-IBOSZNHHSA-N> ;
        dc:identifier       <https://identifiers.org/hmdb/HMDB0001423> ;
        dc:source           "HMDB" ;
        dcterms:identifier  "HMDB0001423" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP561_r142374> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:15346> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/79067> ;
        wp:bdbHmdb          <https://identifiers.org/hmdb/HMDB0001423> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/RGJOEKWQDUBAIZ-IBOSZNHHSA-N> ;
        wp:bdbKeggCompound  <https://identifiers.org/kegg.compound/C00010> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID87642> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q407635> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP561_r142374/DataNode/c8776> ;
        foaf:page           <http://www.hmdb.ca/metabolites/HMDB0001423> .

<http://rdf.wikipathways.org/Pathway/WP561_r142374/WP/Interaction/eead2>
        rdf:type          wp:Catalysis , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP561_r142374> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP561_r142374/Interaction/eead2> ;
        wp:participants   <https://identifiers.org/ncbigene/5498> , <http://rdf.wikipathways.org/Pathway/WP561_r142374/WP/Interaction/e2071> ;
        wp:source         <https://identifiers.org/ncbigene/5498> ;
        wp:target         <http://rdf.wikipathways.org/Pathway/WP561_r142374/WP/Interaction/e2071> .

<http://rdf.wikipathways.org/Pathway/WP561_r142374/WP/Interaction/e81fa>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP561_r142374> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP561_r142374/Interaction/ab3e9> , <http://rdf.wikipathways.org/Pathway/WP561_r142374/Interaction/e4a2e> , <http://rdf.wikipathways.org/Pathway/WP561_r142374/Interaction/e81fa> ;
        wp:participants   <https://identifiers.org/chebi/CHEBI:57307> , <https://identifiers.org/hmdb/HMDB0001967> , <https://identifiers.org/cas/2624-63-7> , <https://identifiers.org/hmdb/HMDB0001377> ;
        wp:source         <https://identifiers.org/hmdb/HMDB0001377> , <https://identifiers.org/cas/2624-63-7> ;
        wp:target         <https://identifiers.org/chebi/CHEBI:57307> , <https://identifiers.org/hmdb/HMDB0001967> .

<https://identifiers.org/ncbigene/212>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "ALAS2" ;
        dc:identifier       <https://identifiers.org/ncbigene/212> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "212" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP561_r142374> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000158578> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/212> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/ALAS2> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A2R8Y782> , <https://identifiers.org/uniprot/P22557> , <https://identifiers.org/uniprot/A0A2R8Y6R4> , <https://identifiers.org/uniprot/A0A2R8Y6N3> , <https://identifiers.org/uniprot/A0A2R8Y836> , <https://identifiers.org/uniprot/H0Y6R3> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP561_r142374/DataNode/a6e> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P22557> , <http://purl.uniprot.org/uniprot/A0A2R8Y6R4> , <http://purl.uniprot.org/uniprot/A0A2R8Y836> , <http://purl.uniprot.org/uniprot/A0A2R8Y6N3> , <http://purl.uniprot.org/uniprot/A0A2R8Y782> , <http://purl.uniprot.org/uniprot/H0Y6R3> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/212> .

<https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=svg&pwTitle=Pathway:WP561&oldid=142374>
        rdf:type        foaf:Image ;
        dcterms:format  "image/svg+xml" .

<http://rdf.wikipathways.org/Pathway/WP561_r142374/WP/Interaction/e2bdd>
        rdf:type          wp:Catalysis , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP561_r142374> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP561_r142374/Interaction/e2bdd> ;
        wp:participants   <https://identifiers.org/ncbigene/210> , <http://rdf.wikipathways.org/Pathway/WP561_r142374/WP/Interaction/d64e8> ;
        wp:source         <https://identifiers.org/ncbigene/210> ;
        wp:target         <http://rdf.wikipathways.org/Pathway/WP561_r142374/WP/Interaction/d64e8> .

<https://identifiers.org/cas/1976-85-8>
        rdf:type            wp:DataNode , wp:Metabolite ;
        rdfs:label          "uroporphyrinogen III" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/HUHWZXWWOFSFKF-UHFFFAOYSA-N> ;
        dc:identifier       <https://identifiers.org/cas/1976-85-8> ;
        dc:source           "CAS" ;
        dcterms:identifier  "1976-85-8" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP561_r142374/WP/Interaction/b0495> , <http://rdf.wikipathways.org/Pathway/WP561_r142374/WP/Interaction/eb348> , <https://identifiers.org/wikipathways/WP561_r142374> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:15437> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/1146> ;
        wp:bdbHmdb          <https://identifiers.org/hmdb/HMDB0001086> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/HUHWZXWWOFSFKF-UHFFFAOYSA-N> ;
        wp:bdbKeggCompound  <https://identifiers.org/kegg.compound/C01051> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID1179> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q897727> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP561_r142374/DataNode/cae> ;
        foaf:page           <https://commonchemistry.cas.org/detail?cas_rn=1976-85-8> .

<https://identifiers.org/hmdb/HMDB0001377>
        rdf:type            wp:DataNode , wp:Metabolite ;
        rdfs:label          "O₂" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/MYMOFIZGZYHOMD-UHFFFAOYSA-N> ;
        dc:identifier       <https://identifiers.org/hmdb/HMDB0001377> ;
        dc:source           "HMDB" ;
        dcterms:identifier  "HMDB0001377" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP561_r142374/WP/Interaction/e81fa> , <http://rdf.wikipathways.org/Pathway/WP561_r142374/WP/Interaction/e2071> , <https://identifiers.org/wikipathways/WP561_r142374> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:15379> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/952> ;
        wp:bdbHmdb          <https://identifiers.org/hmdb/HMDB0001377> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/MYMOFIZGZYHOMD-UHFFFAOYSA-N> ;
        wp:bdbKeggCompound  <https://identifiers.org/kegg.compound/C00007> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID977> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q5203615> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP561_r142374/DataNode/c0252> , <http://rdf.wikipathways.org/Pathway/WP561_r142374/DataNode/a9b4a> ;
        foaf:page           <http://www.hmdb.ca/metabolites/HMDB0001377> .

<https://identifiers.org/chebi/CHEBI:16645>
        rdf:type            wp:Metabolite , wp:DataNode ;
        rdfs:label          "hydroxymethylbilane" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/WDFJYRZCZIUBPR-UHFFFAOYSA-N> ;
        dc:identifier       <https://identifiers.org/chebi/CHEBI:16645> ;
        dc:source           "ChEBI" ;
        dcterms:identifier  "CHEBI:16645" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP561_r142374/WP/Interaction/eb348> , <http://rdf.wikipathways.org/Pathway/WP561_r142374/WP/Interaction/bacc2> , <https://identifiers.org/wikipathways/WP561_r142374> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:16645> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/767> ;
        wp:bdbHmdb          <https://identifiers.org/hmdb/HMDB0001137> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/WDFJYRZCZIUBPR-UHFFFAOYSA-N> ;
        wp:bdbKeggCompound  <https://identifiers.org/kegg.compound/C01024> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID788> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q2639442> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP561_r142374/DataNode/db0> ;
        foaf:page           <https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:16645> .

<https://identifiers.org/wikipathways/WP561>
        pav:hasVersion  <https://identifiers.org/wikipathways/WP561_r142374> .

<https://identifiers.org/pubchem.compound/1038>
        rdf:type            wp:Metabolite , wp:DataNode ;
        rdfs:label          "H⁺" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/GPRLSGONYQIRFK-UHFFFAOYSA-N> ;
        dc:identifier       <https://identifiers.org/pubchem.compound/1038> ;
        dc:source           "PubChem-compound" ;
        dcterms:identifier  "1038" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP561_r142374/WP/Interaction/a6b7b> , <https://identifiers.org/wikipathways/WP561_r142374> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:15378> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/1010> ;
        wp:bdbHmdb          <https://identifiers.org/hmdb/HMDB0059597> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/GPRLSGONYQIRFK-UHFFFAOYSA-N> ;
        wp:bdbKeggCompound  <https://identifiers.org/kegg.compound/C00080> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID1038> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q506710> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP561_r142374/DataNode/b7f31> ;
        foaf:page           <http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=1038> .

<http://rdf.wikipathways.org/Pathway/WP561_r142374/WP/Interaction/e2071>
        rdf:type          wp:Interaction , wp:DirectedInteraction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP561_r142374> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP561_r142374/Interaction/d3bbc> , <http://rdf.wikipathways.org/Pathway/WP561_r142374/Interaction/e2071> , <http://rdf.wikipathways.org/Pathway/WP561_r142374/Interaction/a383f> ;
        wp:participants   <https://identifiers.org/chebi/CHEBI:57307> , <https://identifiers.org/cas/553-12-8> , <https://identifiers.org/hmdb/HMDB0001377> , <https://identifiers.org/hmdb/HMDB0003125> ;
        wp:source         <https://identifiers.org/hmdb/HMDB0001377> , <https://identifiers.org/chebi/CHEBI:57307> ;
        wp:target         <https://identifiers.org/hmdb/HMDB0003125> , <https://identifiers.org/cas/553-12-8> .

<https://identifiers.org/hmdb/HMDB0000123>
        rdf:type            wp:Metabolite , wp:DataNode ;
        rdfs:label          "Glycine" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/DHMQDGOQFOQNFH-UHFFFAOYSA-N> ;
        dc:identifier       <https://identifiers.org/hmdb/HMDB0000123> ;
        dc:source           "HMDB" ;
        dcterms:identifier  "HMDB0000123" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP561_r142374> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:15428> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/730> ;
        wp:bdbHmdb          <https://identifiers.org/hmdb/HMDB0000123> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/DHMQDGOQFOQNFH-UHFFFAOYSA-N> ;
        wp:bdbKeggCompound  <https://identifiers.org/kegg.compound/C00037> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID750> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q106345678> , <http://www.wikidata.org/entity/Q620730> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP561_r142374/DataNode/d77b3> ;
        foaf:page           <http://www.hmdb.ca/metabolites/HMDB0000123> .

<https://identifiers.org/ncbigene/211>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "ALAS1" ;
        dc:identifier       <https://identifiers.org/ncbigene/211> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "211" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP561_r142374> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000023330> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/211> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/ALAS1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/H7C4H7> , <https://identifiers.org/uniprot/Q5JAM2> , <https://identifiers.org/uniprot/H7C5B0> , <https://identifiers.org/uniprot/P13196> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP561_r142374/DataNode/dd6> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/H7C4H7> , <http://purl.uniprot.org/uniprot/Q5JAM2> , <http://purl.uniprot.org/uniprot/H7C5B0> , <http://purl.uniprot.org/uniprot/P13196> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/211> .

<http://rdf.wikipathways.org/Pathway/WP561_r142374/WP/Interaction/ee591>
        rdf:type          wp:Catalysis , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP561_r142374> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP561_r142374/Interaction/ee591> ;
        wp:participants   <https://identifiers.org/ncbigene/3145> , <http://rdf.wikipathways.org/Pathway/WP561_r142374/WP/Interaction/bacc2> ;
        wp:source         <https://identifiers.org/ncbigene/3145> ;
        wp:target         <http://rdf.wikipathways.org/Pathway/WP561_r142374/WP/Interaction/bacc2> .

<http://rdf.wikipathways.org/Pathway/WP561_r142374/WP/Interaction/ddd8c>
        rdf:type          wp:Catalysis , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP561_r142374> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP561_r142374/Interaction/ddd8c> ;
        wp:participants   <https://identifiers.org/ncbigene/1371> , <http://rdf.wikipathways.org/Pathway/WP561_r142374/WP/Interaction/e81fa> ;
        wp:source         <https://identifiers.org/ncbigene/1371> ;
        wp:target         <http://rdf.wikipathways.org/Pathway/WP561_r142374/WP/Interaction/e81fa> .

<https://identifiers.org/hmdb/HMDB0000051>
        rdf:type            wp:DataNode , wp:Metabolite ;
        rdfs:label          "NH₃" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/QGZKDVFQNNGYKY-UHFFFAOYSA-N> ;
        dc:identifier       <https://identifiers.org/hmdb/HMDB0000051> ;
        dc:source           "HMDB" ;
        dcterms:identifier  "HMDB0000051" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP561_r142374> , <http://rdf.wikipathways.org/Pathway/WP561_r142374/WP/Interaction/bacc2> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:16134> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/217> ;
        wp:bdbHmdb          <https://identifiers.org/hmdb/HMDB0000051> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/QGZKDVFQNNGYKY-UHFFFAOYSA-N> ;
        wp:bdbKeggCompound  <https://identifiers.org/kegg.compound/C00014> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID222> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q4087> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP561_r142374/DataNode/ae090> ;
        foaf:page           <http://www.hmdb.ca/metabolites/HMDB0000051> .

<https://identifiers.org/ncbigene/5498>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "PPOX" ;
        dc:identifier       <https://identifiers.org/ncbigene/5498> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "5498" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP561_r142374> , <http://rdf.wikipathways.org/Pathway/WP561_r142374/WP/Interaction/eead2> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000143224> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/5498> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/PPOX> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/H0YFE1> , <https://identifiers.org/uniprot/F5H825> , <https://identifiers.org/uniprot/A0A1W2PNH4> , <https://identifiers.org/uniprot/A0A1W2PPA5> , <https://identifiers.org/uniprot/A0A1W2PRF9> , <https://identifiers.org/uniprot/A0A494C0L4> , <https://identifiers.org/uniprot/D3DVG2> , <https://identifiers.org/uniprot/A0A494C134> , <https://identifiers.org/uniprot/F5H1I5> , <https://identifiers.org/uniprot/P50336> , <https://identifiers.org/uniprot/A0A1W2PQM0> , <https://identifiers.org/uniprot/A0A494C0C8> , <https://identifiers.org/uniprot/A0A494C146> , <https://identifiers.org/uniprot/A0A494C1M8> , <https://identifiers.org/uniprot/H0YFP3> , <https://identifiers.org/uniprot/A0A494C0M9> , <https://identifiers.org/uniprot/A0A494C0D4> , <https://identifiers.org/uniprot/F5GZT7> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP561_r142374/DataNode/ca1> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A494C1M8> , <http://purl.uniprot.org/uniprot/H0YFP3> , <http://purl.uniprot.org/uniprot/P50336> , <http://purl.uniprot.org/uniprot/F5H825> , <http://purl.uniprot.org/uniprot/A0A494C134> , <http://purl.uniprot.org/uniprot/H0YFE1> , <http://purl.uniprot.org/uniprot/A0A494C0C8> , <http://purl.uniprot.org/uniprot/A0A1W2PQM0> , <http://purl.uniprot.org/uniprot/A0A1W2PNH4> , <http://purl.uniprot.org/uniprot/A0A1W2PPA5> , <http://purl.uniprot.org/uniprot/A0A494C146> , <http://purl.uniprot.org/uniprot/D3DVG2> , <http://purl.uniprot.org/uniprot/A0A1W2PRF9> , <http://purl.uniprot.org/uniprot/A0A494C0D4> , <http://purl.uniprot.org/uniprot/F5GZT7> , <http://purl.uniprot.org/uniprot/A0A494C0L4> , <http://purl.uniprot.org/uniprot/F5H1I5> , <http://purl.uniprot.org/uniprot/A0A494C0M9> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/5498> .

<https://identifiers.org/pubchem.compound/27284>
        rdf:type            wp:DataNode , wp:Metabolite ;
        rdfs:label          "Fe²⁺" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/CWYNVVGOOAEACU-UHFFFAOYSA-N> ;
        dc:identifier       <https://identifiers.org/pubchem.compound/27284> ;
        dc:source           "PubChem-compound" ;
        dcterms:identifier  "27284" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP561_r142374/WP/Interaction/a6b7b> , <https://identifiers.org/wikipathways/WP561_r142374> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:29033> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/25394> ;
        wp:bdbHmdb          <https://identifiers.org/hmdb/HMDB0000692> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/CWYNVVGOOAEACU-UHFFFAOYSA-N> ;
        wp:bdbKeggCompound  <https://identifiers.org/kegg.compound/C14818> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID27284> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q428946> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP561_r142374/DataNode/ee779> ;
        foaf:page           <http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=27284> .

<https://identifiers.org/hmdb/HMDB0001967>
        rdf:type            wp:DataNode , wp:Metabolite ;
        rdfs:label          "CO₂" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/CURLTUGMZLYLDI-UHFFFAOYSA-N> ;
        dc:identifier       <https://identifiers.org/hmdb/HMDB0001967> ;
        dc:source           "HMDB" ;
        dcterms:identifier  "HMDB0001967" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP561_r142374/WP/Interaction/e81fa> , <https://identifiers.org/wikipathways/WP561_r142374> , <http://rdf.wikipathways.org/Pathway/WP561_r142374/WP/Interaction/b0495> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:16526> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/274> ;
        wp:bdbHmdb          <https://identifiers.org/hmdb/HMDB0001967> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/CURLTUGMZLYLDI-UHFFFAOYSA-N> ;
        wp:bdbKeggCompound  <https://identifiers.org/kegg.compound/C00011> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID280> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q1997> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP561_r142374/DataNode/cd108> , <http://rdf.wikipathways.org/Pathway/WP561_r142374/DataNode/f73dc> , <http://rdf.wikipathways.org/Pathway/WP561_r142374/DataNode/dc8bb> ;
        foaf:page           <http://www.hmdb.ca/metabolites/HMDB0001967> .

<https://identifiers.org/hmdb/HMDB0001022>
        rdf:type            wp:DataNode , wp:Metabolite ;
        rdfs:label          "succinyl-CoA" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/VNOYUJKHFWYWIR-ITIYDSSPSA-N> ;
        dc:identifier       <https://identifiers.org/hmdb/HMDB0001022> ;
        dc:source           "HMDB" ;
        dcterms:identifier  "HMDB0001022" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP561_r142374> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:15380> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/83179> ;
        wp:bdbHmdb          <https://identifiers.org/hmdb/HMDB0001022> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/VNOYUJKHFWYWIR-ITIYDSSPSA-N> ;
        wp:bdbKeggCompound  <https://identifiers.org/kegg.compound/C00091> ;
        wp:bdbLipidMaps     <https://identifiers.org/lipidmaps/LMFA07050370> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID92133> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q419560> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP561_r142374/DataNode/d6e60> ;
        owl:sameAs          <https://www.lipidmaps.org/rdf/LMFA07050370> ;
        foaf:page           <http://www.hmdb.ca/metabolites/HMDB0001022> .

<https://identifiers.org/cas/553-12-8>
        rdf:type            wp:DataNode , wp:Metabolite ;
        rdfs:label          "protoporphyrin IX" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/KSFOVUSSGSKXFI-UJJXFSCMSA-N> , <https://identifiers.org/inchikey/ZCFFYALKHPIRKJ-UHFFFAOYSA-N> ;
        dc:identifier       <https://identifiers.org/cas/553-12-8> ;
        dc:source           "CAS" ;
        dcterms:identifier  "553-12-8" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP561_r142374/WP/Interaction/a6b7b> , <https://identifiers.org/wikipathways/WP561_r142374> , <http://rdf.wikipathways.org/Pathway/WP561_r142374/WP/Interaction/e2071> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:15430> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/3022121> , <https://identifiers.org/chemspider/4800> , <https://identifiers.org/chemspider/21430808> , <https://identifiers.org/chemspider/23975886> , <https://identifiers.org/chemspider/10469486> ;
        wp:bdbHmdb          <https://identifiers.org/hmdb/HMDB0000241> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/KSFOVUSSGSKXFI-UJJXFSCMSA-N> , <https://identifiers.org/inchikey/ZCFFYALKHPIRKJ-UHFFFAOYSA-N> ;
        wp:bdbKeggCompound  <https://identifiers.org/kegg.compound/C02191> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID4971> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q619815> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP561_r142374/DataNode/fb1> ;
        foaf:page           <https://commonchemistry.cas.org/detail?cas_rn=553-12-8> .

<https://identifiers.org/chemspider/10447539>
        rdf:type            wp:DataNode , wp:Metabolite ;
        rdfs:label          "delta-aminolevulinate" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/ZGXJTSGNIOSYLO-UHFFFAOYSA-N> ;
        dc:identifier       <https://identifiers.org/chemspider/10447539> ;
        dc:source           "Chemspider" ;
        dcterms:identifier  "10447539" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP561_r142374/WP/Interaction/d64e8> , <https://identifiers.org/wikipathways/WP561_r142374> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:12109> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/10447539> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/ZGXJTSGNIOSYLO-UHFFFAOYSA-M> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID16722119> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q27108930> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP561_r142374/DataNode/e69> , <http://rdf.wikipathways.org/Pathway/WP561_r142374/DataNode/dd8> ;
        foaf:page           <https://www.chemspider.com/10447539> .

<https://identifiers.org/ncbigene/7389>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "UROD" ;
        dc:identifier       <https://identifiers.org/ncbigene/7389> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "7389" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP561_r142374> , <http://rdf.wikipathways.org/Pathway/WP561_r142374/WP/Interaction/f55f1> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000126088> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/7389> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/UROD> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A494C0Q8> , <https://identifiers.org/uniprot/A0A494BZY8> , <https://identifiers.org/uniprot/A0A494C1T3> , <https://identifiers.org/uniprot/A0A494C1D8> , <https://identifiers.org/uniprot/A0A494C0P4> , <https://identifiers.org/uniprot/P06132> , <https://identifiers.org/uniprot/A0A494BZV1> , <https://identifiers.org/uniprot/Q5T446> , <https://identifiers.org/uniprot/A0A494C0S8> , <https://identifiers.org/uniprot/A0A494C007> , <https://identifiers.org/uniprot/A0A494C085> , <https://identifiers.org/uniprot/A0A1B0GVZ4> , <https://identifiers.org/uniprot/H0Y5R6> , <https://identifiers.org/uniprot/A0A1B0GVN9> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP561_r142374/DataNode/fe4> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A494C0P4> , <http://purl.uniprot.org/uniprot/A0A1B0GVN9> , <http://purl.uniprot.org/uniprot/P06132> , <http://purl.uniprot.org/uniprot/A0A494C007> , <http://purl.uniprot.org/uniprot/A0A494C0S8> , <http://purl.uniprot.org/uniprot/A0A494C085> , <http://purl.uniprot.org/uniprot/A0A494C0Q8> , <http://purl.uniprot.org/uniprot/Q5T446> , <http://purl.uniprot.org/uniprot/A0A494BZY8> , <http://purl.uniprot.org/uniprot/A0A1B0GVZ4> , <http://purl.uniprot.org/uniprot/A0A494C1T3> , <http://purl.uniprot.org/uniprot/A0A494BZV1> , <http://purl.uniprot.org/uniprot/A0A494C1D8> , <http://purl.uniprot.org/uniprot/H0Y5R6> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/7389> .

<https://identifiers.org/ncbigene/210>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "ALAD" ;
        dc:identifier       <https://identifiers.org/ncbigene/210> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "210" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP561_r142374> , <http://rdf.wikipathways.org/Pathway/WP561_r142374/WP/Interaction/e2bdd> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000148218> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/210> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/ALAD> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/B7ZBK8> , <https://identifiers.org/uniprot/B7ZBK7> , <https://identifiers.org/uniprot/B7ZBK6> , <https://identifiers.org/uniprot/A0A140VJL9> , <https://identifiers.org/uniprot/P13716> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP561_r142374/DataNode/de3> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P13716> , <http://purl.uniprot.org/uniprot/B7ZBK8> , <http://purl.uniprot.org/uniprot/B7ZBK6> , <http://purl.uniprot.org/uniprot/B7ZBK7> , <http://purl.uniprot.org/uniprot/A0A140VJL9> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/210> .

<https://identifiers.org/ncbigene/3145>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "HMBS" ;
        dc:identifier       <https://identifiers.org/ncbigene/3145> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "3145" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP561_r142374> , <http://rdf.wikipathways.org/Pathway/WP561_r142374/WP/Interaction/ee591> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000256269> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/3145> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/HMBS> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A3B3IU56> , <https://identifiers.org/uniprot/A0A3B3IRR1> , <https://identifiers.org/uniprot/A0A3F2YNY7> , <https://identifiers.org/uniprot/F5H4X2> , <https://identifiers.org/uniprot/F5H4W5> , <https://identifiers.org/uniprot/P08397> , <https://identifiers.org/uniprot/A0A1W2PNU5> , <https://identifiers.org/uniprot/A0A3B3IU34> , <https://identifiers.org/uniprot/F5GY90> , <https://identifiers.org/uniprot/F5H4Y7> , <https://identifiers.org/uniprot/F5H226> , <https://identifiers.org/uniprot/F5H345> , <https://identifiers.org/uniprot/A0A8I5KXV4> , <https://identifiers.org/uniprot/A0A3B3IT17> , <https://identifiers.org/uniprot/F5H0P4> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP561_r142374/DataNode/d81> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/F5H4Y7> , <http://purl.uniprot.org/uniprot/A0A3F2YNY7> , <http://purl.uniprot.org/uniprot/A0A3B3IU56> , <http://purl.uniprot.org/uniprot/A0A3B3IRR1> , <http://purl.uniprot.org/uniprot/A0A3B3IU34> , <http://purl.uniprot.org/uniprot/A0A3B3IT17> , <http://purl.uniprot.org/uniprot/F5H345> , <http://purl.uniprot.org/uniprot/F5H4W5> , <http://purl.uniprot.org/uniprot/F5H226> , <http://purl.uniprot.org/uniprot/F5GY90> , <http://purl.uniprot.org/uniprot/P08397> , <http://purl.uniprot.org/uniprot/A0A8I5KXV4> , <http://purl.uniprot.org/uniprot/F5H0P4> , <http://purl.uniprot.org/uniprot/A0A1W2PNU5> , <http://purl.uniprot.org/uniprot/F5H4X2> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/3145> .

<https://identifiers.org/wikipathways/WP561_r142374>
        rdf:type                skos:Collection , wp:Pathway ;
        dc:identifier           <https://identifiers.org/wikipathways/WP561> ;
        dc:source               "WikiPathways" ;
        dc:title                "Heme biosynthesis"@en ;
        dcterms:description     "The enzymatic process that produces heme is porphyrin synthesis. The process is highly conserved across biology. In humans, this pathway serves almost exclusively to form heme.\n\nHeme biosynthesis starts with the synthesis of D-Aminolevulinic acid (dALA or δALA) from the amino acid glycine and succinyl-CoA, which is produced in the TCA cycle (Krebs cycle). This reaction is catalyzed by ALA synthase, which is a rate-limiting enzyme that is regulated by intracellular glucose and heme levels.\n\nThe major organs for heme synthesis are the liver and the bone marrow.\n\nSource: Adapted from [Wikipedia](https://en.wikipedia.org/wiki/Heme)." ;
        dcterms:identifier      "WP561" ;
        dcterms:references      <https://identifiers.org/pubmed/1451437> ;
        cito:cites              <https://identifiers.org/pubmed/1451437> ;
        wp:cellTypeOntologyTag  obo:CL_0000988 , obo:CL_0002092 ;
        wp:isAbout              <http://rdf.wikipathways.org/Pathway/WP561_r142374> ;
        wp:ontologyTag          obo:PW_0000002 , obo:CL_0002092 , obo:PW_0000218 , wp:Curation:AnalysisCollection , obo:CL_0000988 , wp:Curation:MetaKids ;
        wp:organism             obo:NCBITaxon_9606 ;
        wp:organismName         "Homo sapiens" ;
        wp:pathwayOntologyTag   obo:PW_0000002 , obo:PW_0000218 ;
        foaf:img                <https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=png&pwTitle=Pathway:WP561&oldid=142374> , <https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=svg&pwTitle=Pathway:WP561&oldid=142374> ;
        foaf:page               <http://www.wikipathways.org/instance/WP561_r142374> .

<https://identifiers.org/pmc/PMC8116664>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed Central" ;
        dcterms:identifier  "PMC8116664" ;
        cito:cites          <https://identifiers.org/wikipathways/WP561> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/PMC8116664> .

<http://rdf.wikipathways.org/Pathway/WP561_r142374/WP/Interaction/e30ff>
        rdf:type          wp:Catalysis , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP561_r142374> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP561_r142374/Interaction/e30ff> ;
        wp:participants   <https://identifiers.org/ncbigene/2235> , <http://rdf.wikipathways.org/Pathway/WP561_r142374/WP/Interaction/a6b7b> ;
        wp:source         <https://identifiers.org/ncbigene/2235> ;
        wp:target         <http://rdf.wikipathways.org/Pathway/WP561_r142374/WP/Interaction/a6b7b> .

<http://rdf.wikipathways.org/Pathway/WP561_r142374/WP/Interaction/f55f1>
        rdf:type          wp:Catalysis , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP561_r142374> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP561_r142374/Interaction/f55f1> ;
        wp:participants   <https://identifiers.org/ncbigene/7389> , <http://rdf.wikipathways.org/Pathway/WP561_r142374/WP/Interaction/b0495> ;
        wp:source         <https://identifiers.org/ncbigene/7389> ;
        wp:target         <http://rdf.wikipathways.org/Pathway/WP561_r142374/WP/Interaction/b0495> .

<https://identifiers.org/ncbigene/7390>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "UROS" ;
        dc:identifier       <https://identifiers.org/ncbigene/7390> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "7390" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP561_r142374/WP/Interaction/d73d0> , <https://identifiers.org/wikipathways/WP561_r142374> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000188690> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/7390> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/UROS> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A3B3ISX6> , <https://identifiers.org/uniprot/Q5T3L7> , <https://identifiers.org/uniprot/A0A3B3ITJ2> , <https://identifiers.org/uniprot/A0A0S2Z4T8> , <https://identifiers.org/uniprot/A0A3B3ISL9> , <https://identifiers.org/uniprot/Q5T3L9> , <https://identifiers.org/uniprot/A0A3B3ISM6> , <https://identifiers.org/uniprot/A0A3B3IS33> , <https://identifiers.org/uniprot/A0A087WZB7> , <https://identifiers.org/uniprot/A0A087WUV7> , <https://identifiers.org/uniprot/A0A087X021> , <https://identifiers.org/uniprot/A0A3B3IS76> , <https://identifiers.org/uniprot/P10746> , <https://identifiers.org/uniprot/Q5T3L8> , <https://identifiers.org/uniprot/A0A3B3IUC8> , <https://identifiers.org/uniprot/A0A3B3IU75> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP561_r142374/DataNode/e16> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A3B3IU75> , <http://purl.uniprot.org/uniprot/A0A3B3IS76> , <http://purl.uniprot.org/uniprot/A0A3B3ISX6> , <http://purl.uniprot.org/uniprot/A0A3B3IUC8> , <http://purl.uniprot.org/uniprot/Q5T3L9> , <http://purl.uniprot.org/uniprot/Q5T3L8> , <http://purl.uniprot.org/uniprot/A0A0S2Z4T8> , <http://purl.uniprot.org/uniprot/A0A3B3ITJ2> , <http://purl.uniprot.org/uniprot/A0A3B3IS33> , <http://purl.uniprot.org/uniprot/A0A087X021> , <http://purl.uniprot.org/uniprot/A0A087WUV7> , <http://purl.uniprot.org/uniprot/A0A087WZB7> , <http://purl.uniprot.org/uniprot/A0A3B3ISL9> , <http://purl.uniprot.org/uniprot/P10746> , <http://purl.uniprot.org/uniprot/A0A3B3ISM6> , <http://purl.uniprot.org/uniprot/Q5T3L7> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/7390> .

<http://rdf.wikipathways.org/Pathway/WP561_r142374/WP/Interaction/d73d0>
        rdf:type          wp:Catalysis , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP561_r142374> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP561_r142374/Interaction/d73d0> ;
        wp:participants   <https://identifiers.org/ncbigene/7390> , <http://rdf.wikipathways.org/Pathway/WP561_r142374/WP/Interaction/eb348> ;
        wp:source         <https://identifiers.org/ncbigene/7390> ;
        wp:target         <http://rdf.wikipathways.org/Pathway/WP561_r142374/WP/Interaction/eb348> .

<https://identifiers.org/cas/2624-63-7>
        rdf:type            wp:Metabolite , wp:DataNode ;
        rdfs:label          "coproporphyrinogen III" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/NIUVHXTXUXOFEB-UHFFFAOYSA-N> ;
        dc:identifier       <https://identifiers.org/cas/2624-63-7> ;
        dc:source           "CAS" ;
        dcterms:identifier  "2624-63-7" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP561_r142374> , <http://rdf.wikipathways.org/Pathway/WP561_r142374/WP/Interaction/e81fa> , <http://rdf.wikipathways.org/Pathway/WP561_r142374/WP/Interaction/b0495> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:15439> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/315> ;
        wp:bdbHmdb          <https://identifiers.org/hmdb/HMDB0001261> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/NIUVHXTXUXOFEB-UHFFFAOYSA-N> ;
        wp:bdbKeggCompound  <https://identifiers.org/kegg.compound/C03263> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID321> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q2468481> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP561_r142374/DataNode/d92> ;
        foaf:page           <https://commonchemistry.cas.org/detail?cas_rn=2624-63-7> .

<https://identifiers.org/pubmed/1451437>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "1451437" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP561_r142374> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/1451437> .

<http://rdf.wikipathways.org/Pathway/WP561_r142374/WP/Interaction/a6b7b>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP561_r142374> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP561_r142374/Interaction/a86f8> , <http://rdf.wikipathways.org/Pathway/WP561_r142374/Interaction/a0113> , <http://rdf.wikipathways.org/Pathway/WP561_r142374/Interaction/a6b7b> ;
        wp:participants   <https://identifiers.org/pubchem.compound/1038> , <https://identifiers.org/pubchem.compound/27284> , <https://identifiers.org/cas/14875-96-8> , <https://identifiers.org/cas/553-12-8> ;
        wp:source         <https://identifiers.org/pubchem.compound/27284> , <https://identifiers.org/cas/553-12-8> ;
        wp:target         <https://identifiers.org/cas/14875-96-8> , <https://identifiers.org/pubchem.compound/1038> .

<https://identifiers.org/hmdb/HMDB0003125>
        rdf:type            wp:Metabolite , wp:DataNode ;
        rdfs:label          "H₂O₂" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/MHAJPDPJQMAIIY-UHFFFAOYSA-N> ;
        dc:identifier       <https://identifiers.org/hmdb/HMDB0003125> ;
        dc:source           "HMDB" ;
        dcterms:identifier  "HMDB0003125" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP561_r142374/WP/Interaction/e2071> , <https://identifiers.org/wikipathways/WP561_r142374> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:16240> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/763> ;
        wp:bdbHmdb          <https://identifiers.org/hmdb/HMDB0003125> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/MHAJPDPJQMAIIY-UHFFFAOYSA-N> ;
        wp:bdbKeggCompound  <https://identifiers.org/kegg.compound/C00027> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID784> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q171877> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP561_r142374/DataNode/b813b> ;
        foaf:page           <http://www.hmdb.ca/metabolites/HMDB0003125> .
