@prefix biopax:  <http://www.biopax.org/release/biopax-level3.owl#> .
@prefix cito:    <http://purl.org/spar/cito/> .
@prefix dc:      <http://purl.org/dc/elements/1.1/> .
@prefix dcterms: <http://purl.org/dc/terms/> .
@prefix foaf:    <http://xmlns.com/foaf/0.1/> .
@prefix freq:    <http://purl.org/cld/freq/> .
@prefix gpml:    <http://vocabularies.wikipathways.org/gpml#> .
@prefix obo:     <http://purl.obolibrary.org/obo/> .
@prefix owl:     <http://www.w3.org/2002/07/owl#> .
@prefix pav:     <http://purl.org/pav/> .
@prefix prov:    <http://www.w3.org/ns/prov#> .
@prefix rdf:     <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix rdfs:    <http://www.w3.org/2000/01/rdf-schema#> .
@prefix skos:    <http://www.w3.org/2004/02/skos/core#> .
@prefix void:    <http://rdfs.org/ns/void#> .
@prefix wp:      <http://vocabularies.wikipathways.org/wp#> .
@prefix wprdf:   <http://rdf.wikipathways.org/> .
@prefix xsd:     <http://www.w3.org/2001/XMLSchema#> .

<https://identifiers.org/ensembl/ENSG00000224559>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "LINC01087" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000224559> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000224559" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP5223_r140831> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000224559> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/101927994> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/LINC01087> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18074456> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5223_r140831/DataNode/null> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000224559> .

<https://identifiers.org/wikipathways/WP51>
        rdf:type            wp:DataNode , wp:Pathway ;
        rdfs:label          "Regulation of actin cytoskeleton" ;
        dc:identifier       <https://identifiers.org/wikipathways/WP51> ;
        dc:source           "WikiPathways" ;
        dcterms:identifier  "WP51" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP5223_r140831/WP/Interaction/ida4b0d85a> , <https://identifiers.org/wikipathways/WP5223_r140831> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5223_r140831/DataNode/fcd50> ;
        foaf:page           <https://www.wikipathways.org/instance/WP51> .

<https://identifiers.org/wikipathways/WP1859>
        rdf:type            wp:DataNode , wp:Pathway ;
        rdfs:label          "Mitotic G2-G2/M phases" ;
        dc:identifier       <https://identifiers.org/wikipathways/WP1859> ;
        dc:source           "WikiPathways" ;
        dcterms:identifier  "WP1859" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP5223_r140831> , <http://rdf.wikipathways.org/Pathway/WP5223_r140831/WP/Interaction/id874785eb> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5223_r140831/DataNode/aa3c3> ;
        foaf:page           <https://www.wikipathways.org/instance/WP1859> .

<http://rdf.wikipathways.org/Pathway/WP5223_r140831/WP/Interaction/ida5bfc77f>
        rdf:type            wp:Interaction , wp:Stimulation , wp:DirectedInteraction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP5223_r140831> ;
        dcterms:references  <https://identifiers.org/pubmed/20716133> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5223_r140831/Interaction/ida5bfc77f> ;
        wp:participants     <https://identifiers.org/ensembl/ENSG00000152102> , <https://identifiers.org/ensembl/ENSG00000104435> ;
        wp:source           <https://identifiers.org/ensembl/ENSG00000152102> ;
        wp:target           <https://identifiers.org/ensembl/ENSG00000104435> .

<http://rdf.wikipathways.org/Pathway/WP5223_r140831/WP/Interaction/ida4b0d85a>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP5223_r140831> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP5223_r140831/Interaction/ida4b0d85a> ;
        wp:participants   <https://identifiers.org/wikipathways/WP51> , <https://identifiers.org/ensembl/ENSG00000134982> ;
        wp:source         <https://identifiers.org/ensembl/ENSG00000134982> ;
        wp:target         <https://identifiers.org/wikipathways/WP51> .

<http://rdf.wikipathways.org/Pathway/WP5223_r140831/WP/Interaction/id874785eb>
        rdf:type            wp:Interaction , wp:DirectedInteraction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP5223_r140831> ;
        dcterms:references  <https://identifiers.org/pubmed/23921553> , <https://identifiers.org/pubmed/11956313> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5223_r140831/Interaction/id874785eb> ;
        wp:participants     <https://identifiers.org/ensembl/ENSG00000173272> , <https://identifiers.org/wikipathways/WP1859> ;
        wp:source           <https://identifiers.org/ensembl/ENSG00000173272> ;
        wp:target           <https://identifiers.org/wikipathways/WP1859> .

<http://rdf.wikipathways.org/Pathway/WP5223_r140831/ComplexBinding/d7598>
        rdf:type          wp:ComplexBinding , wp:Binding , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP5223_r140831> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP5223_r140831/Group/d7598> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000067560> , <https://identifiers.org/chebi/CHEBI:17552> , <http://rdf.wikipathways.org/Pathway/WP5223_r140831/Complex/d7598> .

<https://identifiers.org/ensembl/ENSG00000178171>
        rdf:type            wp:DataNode , wp:GeneProduct , wp:Protein ;
        rdfs:label          "AMER3" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000178171> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000178171" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP5223_r140831> , <http://rdf.wikipathways.org/Pathway/WP5223_r140831/WP/Interaction/idaba1c3ee> , <http://rdf.wikipathways.org/Pathway/WP5223_r140831/WP/Interaction/id1de27818> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000178171> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/205147> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/AMER3> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q8N944> , <https://identifiers.org/uniprot/C9J4B8> , <https://identifiers.org/uniprot/C9JS07> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18053308> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5223_r140831/DataNode/da444> , <http://rdf.wikipathways.org/Pathway/WP5223_r140831/DataNode/f3a3d> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/C9J4B8> , <http://purl.uniprot.org/uniprot/Q8N944> , <http://purl.uniprot.org/uniprot/C9JS07> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000178171> .

<http://rdf.wikipathways.org/Pathway/WP5223_r140831/ComplexBinding/bb663>
        rdf:type          wp:ComplexBinding , wp:Binding , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP5223_r140831> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP5223_r140831/Group/bb663> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000067560> , <https://identifiers.org/chebi/CHEBI:37565> , <http://rdf.wikipathways.org/Pathway/WP5223_r140831/Complex/bb663> .

<https://identifiers.org/ensembl/ENSG00000163040>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "CCDC74A" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000163040> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000163040" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP5223_r140831> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000163040> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/90557> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/CCDC74A> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/F8WEI8> , <https://identifiers.org/uniprot/F5GZA4> , <https://identifiers.org/uniprot/Q96AQ1> , <https://identifiers.org/uniprot/A0A384MR57> , <https://identifiers.org/uniprot/C9IYK9> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18048396> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5223_r140831/DataNode/c616f> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q96AQ1> , <http://purl.uniprot.org/uniprot/F8WEI8> , <http://purl.uniprot.org/uniprot/C9IYK9> , <http://purl.uniprot.org/uniprot/F5GZA4> , <http://purl.uniprot.org/uniprot/A0A384MR57> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000163040> .

<https://identifiers.org/wikipathways/WP428>
        rdf:type            wp:Pathway , wp:DataNode ;
        rdfs:label          "Canonical Wnt signaling" ;
        dc:identifier       <https://identifiers.org/wikipathways/WP428> ;
        dc:source           "WikiPathways" ;
        dcterms:identifier  "WP428" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP5223_r140831/WP/Interaction/idc339a3c2> , <https://identifiers.org/wikipathways/WP5223_r140831> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5223_r140831/DataNode/b4655> ;
        foaf:page           <https://www.wikipathways.org/instance/WP428> .

<https://identifiers.org/ensembl/ENSG00000161973>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "CCDC42" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000161973> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000161973" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP5223_r140831/Complex/b6ce7> , <https://identifiers.org/wikipathways/WP5223_r140831> , <http://rdf.wikipathways.org/Pathway/WP5223_r140831/Complex/aa225> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000161973> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/146849> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/CCDC42> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q96M95> , <https://identifiers.org/uniprot/J3KSK0> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18051482> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5223_r140831/DataNode/b6864> , <http://rdf.wikipathways.org/Pathway/WP5223_r140831/DataNode/e7fb5> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q96M95> , <http://purl.uniprot.org/uniprot/J3KSK0> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000161973> .

<https://identifiers.org/wikipathways/WP5223>
        pav:hasVersion  <https://identifiers.org/wikipathways/WP5223_r140831> .

<https://identifiers.org/wikipathways/WP2652>
        rdf:type            wp:DataNode , wp:Pathway ;
        rdfs:label          "Mitotic prometaphase" ;
        dc:identifier       <https://identifiers.org/wikipathways/WP2652> ;
        dc:source           "WikiPathways" ;
        dcterms:identifier  "WP2652" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP5223_r140831> , <http://rdf.wikipathways.org/Pathway/WP5223_r140831/WP/Interaction/f65f5> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5223_r140831/DataNode/ae6b6> ;
        foaf:page           <https://www.wikipathways.org/instance/WP2652> .

<http://rdf.wikipathways.org/Pathway/WP5223_r140831/WP/Interaction/f65f5>
        rdf:type            wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP5223_r140831> ;
        dcterms:references  <https://identifiers.org/pubmed/23921553> , <https://identifiers.org/pubmed/11956313> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5223_r140831/Interaction/f65f5> ;
        wp:participants     <https://identifiers.org/ensembl/ENSG00000173272> , <https://identifiers.org/wikipathways/WP2652> ;
        wp:source           <https://identifiers.org/ensembl/ENSG00000173272> ;
        wp:target           <https://identifiers.org/wikipathways/WP2652> .

<https://identifiers.org/pubmed/24251807>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "24251807" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP5223_r140831/WP/Interaction/idc339a3c2> , <http://rdf.wikipathways.org/Pathway/WP5223_r140831/WP/Interaction/idaba1c3ee> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/24251807> .

<http://rdf.wikipathways.org/Pathway/WP5223_r140831/Complex/ecf19>
        rdf:type          wp:Complex , wp:DataNode ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP5223_r140831> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP5223_r140831/Group/ecf19> ;
        wp:participants   <https://identifiers.org/chebi/CHEBI:17552> , <https://identifiers.org/ensembl/ENSG00000136238> .

<https://doi.org/10.1038%2FEMBOJ.2013.172>
        dc:source           "DOI" ;
        dcterms:identifier  "10.1038/EMBOJ.2013.172" .

<https://identifiers.org/pubmed/11956313>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "11956313" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP5223_r140831/WP/Interaction/f65f5> , <http://rdf.wikipathways.org/Pathway/WP5223_r140831/WP/Interaction/id874785eb> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/11956313> .

<https://identifiers.org/ensembl/ENSG00000136002>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "ARHGEF4" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000136002> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000136002" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP5223_r140831> , <http://rdf.wikipathways.org/Pathway/WP5223_r140831/WP/Interaction/ide5306acd> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000136002> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/50649> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/ARHGEF4> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/E7EV07> , <https://identifiers.org/uniprot/A0A0C4DFY6> , <https://identifiers.org/uniprot/A0A087X0P1> , <https://identifiers.org/uniprot/H0Y451> , <https://identifiers.org/uniprot/E9PEM0> , <https://identifiers.org/uniprot/A0A1B0GW00> , <https://identifiers.org/uniprot/A4QPB6> , <https://identifiers.org/uniprot/Q9NR80> , <https://identifiers.org/uniprot/H0YCT6> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18039841> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5223_r140831/DataNode/c2ff3> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A087X0P1> , <http://purl.uniprot.org/uniprot/E9PEM0> , <http://purl.uniprot.org/uniprot/A0A0C4DFY6> , <http://purl.uniprot.org/uniprot/H0Y451> , <http://purl.uniprot.org/uniprot/Q9NR80> , <http://purl.uniprot.org/uniprot/H0YCT6> , <http://purl.uniprot.org/uniprot/E7EV07> , <http://purl.uniprot.org/uniprot/A4QPB6> , <http://purl.uniprot.org/uniprot/A0A1B0GW00> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000136002> .

<https://identifiers.org/ensembl/ENSG00000004897>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "CDC27" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000004897> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000004897" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP5223_r140831/WP/Interaction/ide8483a1c> , <https://identifiers.org/wikipathways/WP5223_r140831> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000004897> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/996> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/CDC27> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/I3L394> , <https://identifiers.org/uniprot/I3L225> , <https://identifiers.org/uniprot/F6QPS0> , <https://identifiers.org/uniprot/I3L3G1> , <https://identifiers.org/uniprot/K7EMA6> , <https://identifiers.org/uniprot/P30260> , <https://identifiers.org/uniprot/G5EA36> , <https://identifiers.org/uniprot/I3L1K3> , <https://identifiers.org/uniprot/E9PRZ6> , <https://identifiers.org/uniprot/I3L3Y5> , <https://identifiers.org/uniprot/I3L328> , <https://identifiers.org/uniprot/I3L2Z8> , <https://identifiers.org/uniprot/I3L3H6> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q17859768> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5223_r140831/DataNode/ace0f> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/I3L394> , <http://purl.uniprot.org/uniprot/I3L1K3> , <http://purl.uniprot.org/uniprot/K7EMA6> , <http://purl.uniprot.org/uniprot/I3L3Y5> , <http://purl.uniprot.org/uniprot/G5EA36> , <http://purl.uniprot.org/uniprot/I3L225> , <http://purl.uniprot.org/uniprot/E9PRZ6> , <http://purl.uniprot.org/uniprot/I3L328> , <http://purl.uniprot.org/uniprot/I3L3H6> , <http://purl.uniprot.org/uniprot/F6QPS0> , <http://purl.uniprot.org/uniprot/I3L3G1> , <http://purl.uniprot.org/uniprot/P30260> , <http://purl.uniprot.org/uniprot/I3L2Z8> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000004897> .

<https://identifiers.org/pubmed/20716133>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "20716133" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP5223_r140831/WP/Interaction/ideb5a87e5> , <http://rdf.wikipathways.org/Pathway/WP5223_r140831/WP/Interaction/ide8483a1c> , <http://rdf.wikipathways.org/Pathway/WP5223_r140831/WP/Interaction/ida5bfc77f> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/20716133> .

<https://identifiers.org/ensembl/ENSG00000223631>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "LINC01120" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000223631> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000223631" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP5223_r140831> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000223631> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/LINC01120> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18056593> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5223_r140831/DataNode/null> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000223631> .

<http://rdf.wikipathways.org/Pathway/WP5223_r140831/WP/Interaction/id1de27818>
        rdf:type          wp:TranscriptionTranslation , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP5223_r140831> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP5223_r140831/Interaction/id1de27818> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000178171> ;
        wp:source         <https://identifiers.org/ensembl/ENSG00000178171> ;
        wp:target         <https://identifiers.org/ensembl/ENSG00000178171> .

<http://rdf.wikipathways.org/Pathway/WP5223_r140831/WP/Interaction/ide5306acd>
        rdf:type            wp:Binding , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP5223_r140831> ;
        dcterms:references  <https://identifiers.org/pubmed/12598901> , <https://identifiers.org/pubmed/10947987> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5223_r140831/Interaction/ide5306acd> ;
        wp:participants     <https://identifiers.org/ensembl/ENSG00000134982> , <https://identifiers.org/ensembl/ENSG00000136002> ;
        wp:source           <https://identifiers.org/ensembl/ENSG00000136002> ;
        wp:target           <https://identifiers.org/ensembl/ENSG00000134982> .

<https://identifiers.org/wikipathways/WP5223_r140831>
        rdf:type               skos:Collection , wp:Pathway ;
        dc:identifier          <https://identifiers.org/wikipathways/WP5223> ;
        dc:source              "WikiPathways" ;
        dc:title               "2q21.1 copy number variation syndrome"@en ;
        dcterms:description    "The 2q21.1 copy number variation syndrome can result in the loss of up to 9 protein-coding genes. Deletions and duplications in 2q21.1 were reported to be connected to intellectual disability, hyperactivity, and aggressive behavior (DOI: 10.1002/mgg3.1135,DOI: 10.1002/ajmg.a.36357). The clinical picture was explained by alterations in five genes important for neurological development, namely GPR148, FAM123C, ARHGEF4, FAM168B and PLEKHB2 (DOI: 10.1002/ajmg.a.36357,DOI: 10.1093/hmg/dds166). Analogically, changes in tubulin genes in 2q21.1 were linked to Motor Timing in ADHD (DOI: 10.1016/j.ajhg.2008.06.006). For this rare disorder, two different genomic locations are known according to Kirov et al. 2014 and literature cited there and Gimelli et al. 2014 with a larger deletion.  " ;
        dcterms:identifier     "WP5223" ;
        dcterms:references     <https://identifiers.org/pubmed/24591035> ;
        cito:cites             <https://identifiers.org/pubmed/24251807> , <https://identifiers.org/pubmed/11956313> , <https://identifiers.org/pubmed/10947987> , <https://identifiers.org/pubmed/30420269> , <https://identifiers.org/pubmed/22771904> , <https://identifiers.org/pubmed/20716133> , <https://identifiers.org/pubmed/24591035> , <https://identifiers.org/pubmed/12598901> , <https://identifiers.org/pubmed/23921553> ;
        wp:diseaseOntologyTag  obo:DOID_0060388 , obo:DOID_0060429 ;
        wp:isAbout             <http://rdf.wikipathways.org/Pathway/WP5223_r140831> ;
        wp:ontologyTag         obo:PW_0000013 , wp:Curation:AnalysisCollection , obo:DOID_0060429 , wp:Curation:ONTOX , obo:DOID_0060388 , wp:Curation:RareDiseases ;
        wp:organism            obo:NCBITaxon_9606 ;
        wp:organismName        "Homo sapiens" ;
        wp:pathwayOntologyTag  obo:PW_0000013 ;
        foaf:img               <https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=svg&pwTitle=Pathway:WP5223&oldid=140831> , <https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=png&pwTitle=Pathway:WP5223&oldid=140831> ;
        foaf:page              <http://www.wikipathways.org/instance/WP5223_r140831> .

obo:NCBITaxon_9606  obo:NCIT_C179773  "9606" .

<https://identifiers.org/chebi/CHEBI:37565>
        rdf:type            wp:Metabolite , wp:DataNode ;
        rdfs:label          "GTP" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/XKMLYUALXHKNFT-UUOKFMHZSA-N> ;
        dc:identifier       <https://identifiers.org/chebi/CHEBI:37565> ;
        dc:source           "ChEBI" ;
        dcterms:identifier  "CHEBI:37565" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP5223_r140831/Complex/bb663> , <http://rdf.wikipathways.org/Pathway/WP5223_r140831/Complex/b5d84> , <https://identifiers.org/wikipathways/WP5223_r140831> , <http://rdf.wikipathways.org/Pathway/WP5223_r140831/Complex/b6ce7> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:37565> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/5414499> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/XKMLYUALXHKNFT-UUOKFMHZSA-J> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID7058167> , <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID135398632> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q27117191> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5223_r140831/DataNode/e5fbf> , <http://rdf.wikipathways.org/Pathway/WP5223_r140831/DataNode/f3e30> , <http://rdf.wikipathways.org/Pathway/WP5223_r140831/DataNode/dcd94> ;
        foaf:page           <https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:37565> .

<https://identifiers.org/ensembl/ENSG00000173272>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "MZT2A" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000173272> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000173272" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP5223_r140831/WP/Interaction/f65f5> , <https://identifiers.org/wikipathways/WP5223_r140831> , <http://rdf.wikipathways.org/Pathway/WP5223_r140831/WP/Interaction/id874785eb> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000173272> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/653784> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/MZT2A> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/H7C202> , <https://identifiers.org/uniprot/Q6P582> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18060677> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5223_r140831/DataNode/dc5a0> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/H7C202> , <http://purl.uniprot.org/uniprot/Q6P582> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000173272> .

<https://identifiers.org/pubmed/22771904>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "22771904" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP5223_r140831/WP/Interaction/ide8483a1c> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/22771904> .

<https://identifiers.org/ensembl/ENSG00000188219>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "POTEE" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000188219> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000188219" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP5223_r140831> , <http://rdf.wikipathways.org/Pathway/WP5223_r140831/WP/Interaction/id402880c8> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000188219> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/445582> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/POTEE> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q6S8J3> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18058856> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5223_r140831/DataNode/bb878> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q6S8J3> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000188219> .

<https://identifiers.org/pubmed/30420269>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "30420269" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP5223_r140831/WP/Interaction/id402880c8> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/30420269> .

<http://rdf.wikipathways.org/Pathway/WP5223_r140831/ComplexBinding/ecf19>
        rdf:type          wp:ComplexBinding , wp:Binding , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP5223_r140831> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP5223_r140831/Group/ecf19> ;
        wp:participants   <https://identifiers.org/chebi/CHEBI:17552> , <https://identifiers.org/ensembl/ENSG00000136238> , <http://rdf.wikipathways.org/Pathway/WP5223_r140831/Complex/ecf19> .

<https://identifiers.org/ensembl/ENSG00000104435>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "STMN2" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000104435> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000104435" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP5223_r140831/WP/Interaction/ida5bfc77f> , <https://identifiers.org/wikipathways/WP5223_r140831> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000104435> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/11075> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/STMN2> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/E5RGX5> , <https://identifiers.org/uniprot/Q93045> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18036104> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5223_r140831/DataNode/cae8f> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q93045> , <http://purl.uniprot.org/uniprot/E5RGX5> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000104435> .

<https://identifiers.org/chebi/CHEBI:17552>
        rdf:type            wp:DataNode , wp:Metabolite ;
        rdfs:label          "GDP" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/QGWNDRXFNXRZMB-UUOKFMHZSA-N> ;
        dc:identifier       <https://identifiers.org/chebi/CHEBI:17552> ;
        dc:source           "ChEBI" ;
        dcterms:identifier  "CHEBI:17552" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP5223_r140831> , <http://rdf.wikipathways.org/Pathway/WP5223_r140831/Complex/d7598> , <http://rdf.wikipathways.org/Pathway/WP5223_r140831/Complex/ecf19> , <http://rdf.wikipathways.org/Pathway/WP5223_r140831/Complex/aa225> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:17552> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/8630> ;
        wp:bdbHmdb          <https://identifiers.org/hmdb/HMDB0001201> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/QGWNDRXFNXRZMB-UUOKFMHZSA-N> ;
        wp:bdbKeggCompound  <https://identifiers.org/kegg.compound/C00035> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID135398619> , <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID8977> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q422582> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5223_r140831/DataNode/cd9a3> , <http://rdf.wikipathways.org/Pathway/WP5223_r140831/DataNode/aac3e> , <http://rdf.wikipathways.org/Pathway/WP5223_r140831/DataNode/da818> ;
        foaf:page           <https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:17552> .

<http://rdf.wikipathways.org/Pathway/WP5223_r140831/Complex/aa225>
        rdf:type          wp:Complex , wp:DataNode ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP5223_r140831> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP5223_r140831/Group/aa225> ;
        wp:participants   <https://identifiers.org/chebi/CHEBI:17552> , <https://identifiers.org/ensembl/ENSG00000161973> .

<https://identifiers.org/ensembl/ENSG00000115762>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "PLEKHB2" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000115762> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000115762" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP5223_r140831> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000115762> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/55041> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/PLEKHB2> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A0A0MSI4> , <https://identifiers.org/uniprot/A0A024QZ35> , <https://identifiers.org/uniprot/A0A0A0MSE9> , <https://identifiers.org/uniprot/Q96CS7> , <https://identifiers.org/uniprot/B7WPA5> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18041505> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5223_r140831/DataNode/c6c9b> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A024QZ35> , <http://purl.uniprot.org/uniprot/A0A0A0MSE9> , <http://purl.uniprot.org/uniprot/B7WPA5> , <http://purl.uniprot.org/uniprot/A0A0A0MSI4> , <http://purl.uniprot.org/uniprot/Q96CS7> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000115762> .

<https://identifiers.org/ensembl/ENSG00000284149>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "MIR4784" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000284149> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000284149" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP5223_r140831> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000284149> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/100616378> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/MIR4784> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18068798> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5223_r140831/DataNode/null> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000284149> .

<https://identifiers.org/ensembl/ENSG00000134982>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "APC" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000134982> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000134982" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP5223_r140831> , <http://rdf.wikipathways.org/Pathway/WP5223_r140831/WP/Interaction/ida4b0d85a> , <http://rdf.wikipathways.org/Pathway/WP5223_r140831/WP/Interaction/ide5306acd> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000134982> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/324> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/APC> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/R4GMU6> , <https://identifiers.org/uniprot/E9PFT7> , <https://identifiers.org/uniprot/A0A087WYF3> , <https://identifiers.org/uniprot/E7EMH9> , <https://identifiers.org/uniprot/D6RFL6> , <https://identifiers.org/uniprot/P25054> , <https://identifiers.org/uniprot/A0A2Q2SV78> , <https://identifiers.org/uniprot/A0A087X2F3> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q14883378> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5223_r140831/DataNode/cf0fa> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A2Q2SV78> , <http://purl.uniprot.org/uniprot/A0A087WYF3> , <http://purl.uniprot.org/uniprot/A0A087X2F3> , <http://purl.uniprot.org/uniprot/D6RFL6> , <http://purl.uniprot.org/uniprot/E9PFT7> , <http://purl.uniprot.org/uniprot/E7EMH9> , <http://purl.uniprot.org/uniprot/P25054> , <http://purl.uniprot.org/uniprot/R4GMU6> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000134982> .

<https://identifiers.org/ensembl/ENSG00000173302>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "GPR148" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000173302> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000173302" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP5223_r140831> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000173302> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/344561> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/GPR148> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q8TDV2> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18055597> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5223_r140831/DataNode/c519a> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q8TDV2> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000173302> .

<https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=svg&pwTitle=Pathway:WP5223&oldid=140831>
        rdf:type        foaf:Image ;
        dcterms:format  "image/svg+xml" .

<https://identifiers.org/ensembl/ENSG00000152102>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "FAM168B" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000152102> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000152102" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP5223_r140831> , <http://rdf.wikipathways.org/Pathway/WP5223_r140831/WP/Interaction/ida5bfc77f> , <http://rdf.wikipathways.org/Pathway/WP5223_r140831/WP/Interaction/ideb5a87e5> , <http://rdf.wikipathways.org/Pathway/WP5223_r140831/WP/Interaction/ide8483a1c> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000152102> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/130074> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/FAM168B> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A024QZ31> , <https://identifiers.org/uniprot/A1KXE4> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18049970> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5223_r140831/DataNode/f1015> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A024QZ31> , <http://purl.uniprot.org/uniprot/A1KXE4> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000152102> .

<https://identifiers.org/wikipathways/WP1471>
        rdf:type            wp:Pathway , wp:DataNode ;
        rdfs:label          "mTORC2" ;
        dc:identifier       <https://identifiers.org/wikipathways/WP1471> ;
        dc:source           "WikiPathways" ;
        dcterms:identifier  "WP1471" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP5223_r140831/WP/Interaction/id402880c8> , <https://identifiers.org/wikipathways/WP5223_r140831> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5223_r140831/DataNode/f96d5> ;
        foaf:page           <https://www.wikipathways.org/instance/WP1471> .

<http://rdf.wikipathways.org/Pathway/WP5223_r140831/Complex/b5d84>
        rdf:type          wp:Complex , wp:DataNode ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP5223_r140831> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP5223_r140831/Group/b5d84> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000136238> , <https://identifiers.org/chebi/CHEBI:37565> .

<https://identifiers.org/ensembl/ENSG00000075886>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "TUBA3D" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000075886> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000075886" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP5223_r140831> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000075886> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/113457> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/TUBA3D> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/P0DPH8> , <https://identifiers.org/uniprot/Q1ZYQ1> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18048912> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5223_r140831/DataNode/f5801> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P0DPH8> , <http://purl.uniprot.org/uniprot/Q1ZYQ1> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000075886> .

<http://rdf.wikipathways.org/Pathway/WP5223_r140831/Complex/b6ce7>
        rdf:type          wp:Complex , wp:DataNode ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP5223_r140831> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP5223_r140831/Group/b6ce7> ;
        wp:participants   <https://identifiers.org/chebi/CHEBI:37565> , <https://identifiers.org/ensembl/ENSG00000161973> .

<http://rdf.wikipathways.org/Pathway/WP5223_r140831/WP/Interaction/idc339a3c2>
        rdf:type            wp:DirectedInteraction , wp:Interaction , wp:Stimulation ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP5223_r140831> ;
        dcterms:references  <https://identifiers.org/pubmed/24251807> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5223_r140831/Interaction/idc339a3c2> ;
        wp:participants     <https://identifiers.org/chebi/CHEBI:18348> , <https://identifiers.org/wikipathways/WP428> ;
        wp:source           <https://identifiers.org/chebi/CHEBI:18348> ;
        wp:target           <https://identifiers.org/wikipathways/WP428> .

<http://rdf.wikipathways.org/Pathway/WP5223_r140831/WP/Interaction/idaba1c3ee>
        rdf:type            wp:Interaction , wp:Binding , wp:DirectedInteraction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP5223_r140831> ;
        dcterms:references  <https://identifiers.org/pubmed/24251807> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5223_r140831/Interaction/idaba1c3ee> ;
        wp:participants     <https://identifiers.org/chebi/CHEBI:18348> , <https://identifiers.org/ensembl/ENSG00000178171> ;
        wp:source           <https://identifiers.org/ensembl/ENSG00000178171> ;
        wp:target           <https://identifiers.org/chebi/CHEBI:18348> .

<https://identifiers.org/ensembl/ENSG00000067560>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "RHOA" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000067560> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000067560" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP5223_r140831/Complex/d7598> , <http://rdf.wikipathways.org/Pathway/WP5223_r140831/Complex/bb663> , <https://identifiers.org/wikipathways/WP5223_r140831> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000067560> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/387> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/RHOA> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A7I2V3G1> , <https://identifiers.org/uniprot/A0A024R324> , <https://identifiers.org/uniprot/C9JNR4> , <https://identifiers.org/uniprot/A0A7I2YQV1> , <https://identifiers.org/uniprot/C9JX21> , <https://identifiers.org/uniprot/C9JRM1> , <https://identifiers.org/uniprot/P61586> , <https://identifiers.org/uniprot/A0A7I2V5E6> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q15331450> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5223_r140831/DataNode/e9a7c> , <http://rdf.wikipathways.org/Pathway/WP5223_r140831/DataNode/b9753> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A7I2V3G1> , <http://purl.uniprot.org/uniprot/C9JNR4> , <http://purl.uniprot.org/uniprot/A0A7I2V5E6> , <http://purl.uniprot.org/uniprot/C9JRM1> , <http://purl.uniprot.org/uniprot/P61586> , <http://purl.uniprot.org/uniprot/A0A024R324> , <http://purl.uniprot.org/uniprot/C9JX21> , <http://purl.uniprot.org/uniprot/A0A7I2YQV1> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000067560> .

<https://identifiers.org/pubmed/24591035>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "24591035" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP5223_r140831> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/24591035> .

<https://identifiers.org/pubmed/12598901>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "12598901" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP5223_r140831/WP/Interaction/ide5306acd> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/12598901> .

<https://identifiers.org/ensembl/ENSG00000168610>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "STAT3" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000168610> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000168610" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP5223_r140831/WP/Interaction/ideb5a87e5> , <https://identifiers.org/wikipathways/WP5223_r140831> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000168610> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/6774> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/STAT3> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A7I2V444> , <https://identifiers.org/uniprot/A0A7I2V552> , <https://identifiers.org/uniprot/A0A7I2YQI1> , <https://identifiers.org/uniprot/A0A7I2V4F6> , <https://identifiers.org/uniprot/A0A7I2V4R2> , <https://identifiers.org/uniprot/A0A7I2V4C8> , <https://identifiers.org/uniprot/G8JLH9> , <https://identifiers.org/uniprot/A0A7I2V395> , <https://identifiers.org/uniprot/A0A7I2V3V0> , <https://identifiers.org/uniprot/A0A7I2V5N9> , <https://identifiers.org/uniprot/P40763> , <https://identifiers.org/uniprot/A0A7I2V2T1> , <https://identifiers.org/uniprot/A0A7I2V4R3> , <https://identifiers.org/uniprot/A0A7I2V2G1> , <https://identifiers.org/uniprot/A0A7I2YQR5> , <https://identifiers.org/uniprot/A0A7I2YQD2> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q14912019> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5223_r140831/DataNode/bd9dd> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A7I2YQI1> , <http://purl.uniprot.org/uniprot/P40763> , <http://purl.uniprot.org/uniprot/A0A7I2V552> , <http://purl.uniprot.org/uniprot/A0A7I2V444> , <http://purl.uniprot.org/uniprot/A0A7I2YQD2> , <http://purl.uniprot.org/uniprot/A0A7I2V4R2> , <http://purl.uniprot.org/uniprot/A0A7I2V3V0> , <http://purl.uniprot.org/uniprot/A0A7I2V2G1> , <http://purl.uniprot.org/uniprot/A0A7I2V395> , <http://purl.uniprot.org/uniprot/A0A7I2V4C8> , <http://purl.uniprot.org/uniprot/A0A7I2V5N9> , <http://purl.uniprot.org/uniprot/A0A7I2YQR5> , <http://purl.uniprot.org/uniprot/A0A7I2V4R3> , <http://purl.uniprot.org/uniprot/A0A7I2V2T1> , <http://purl.uniprot.org/uniprot/A0A7I2V4F6> , <http://purl.uniprot.org/uniprot/G8JLH9> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000168610> .

<http://rdf.wikipathways.org/Pathway/WP5223_r140831/ComplexBinding/aa225>
        rdf:type          wp:ComplexBinding , wp:Binding , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP5223_r140831> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP5223_r140831/Group/aa225> ;
        wp:participants   <https://identifiers.org/chebi/CHEBI:17552> , <https://identifiers.org/ensembl/ENSG00000161973> , <http://rdf.wikipathways.org/Pathway/WP5223_r140831/Complex/aa225> .

<https://identifiers.org/ensembl/ENSG00000136238>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "RAC1" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000136238> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000136238" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP5223_r140831> , <http://rdf.wikipathways.org/Pathway/WP5223_r140831/Complex/ecf19> , <http://rdf.wikipathways.org/Pathway/WP5223_r140831/Complex/b5d84> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000136238> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/5879> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/RAC1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A4D2P1> , <https://identifiers.org/uniprot/A0A994J4S4> , <https://identifiers.org/uniprot/A4D2P0> , <https://identifiers.org/uniprot/A0A994J6T1> , <https://identifiers.org/uniprot/P63000> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q15325735> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5223_r140831/DataNode/a6ace> , <http://rdf.wikipathways.org/Pathway/WP5223_r140831/DataNode/a162e> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A994J6T1> , <http://purl.uniprot.org/uniprot/A0A994J4S4> , <http://purl.uniprot.org/uniprot/A4D2P0> , <http://purl.uniprot.org/uniprot/A4D2P1> , <http://purl.uniprot.org/uniprot/P63000> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000136238> .

<https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=png&pwTitle=Pathway:WP5223&oldid=140831>
        rdf:type        foaf:Image ;
        dcterms:format  "image/png" .

<http://rdf.wikipathways.org/Pathway/WP5223_r140831/Complex/d7598>
        rdf:type          wp:Complex , wp:DataNode ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP5223_r140831> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP5223_r140831/Group/d7598> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000067560> , <https://identifiers.org/chebi/CHEBI:17552> .

<https://identifiers.org/pubmed/23921553>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "23921553" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP5223_r140831/WP/Interaction/f65f5> , <http://rdf.wikipathways.org/Pathway/WP5223_r140831/WP/Interaction/id874785eb> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q29871442> ;
        owl:sameAs          <https://doi.org/10.1038%2FEMBOJ.2013.172> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/23921553> .

<http://rdf.wikipathways.org/Pathway/WP5223_r140831/ComplexBinding/b5d84>
        rdf:type          wp:ComplexBinding , wp:Binding , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP5223_r140831> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP5223_r140831/Group/b5d84> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000136238> , <https://identifiers.org/chebi/CHEBI:37565> , <http://rdf.wikipathways.org/Pathway/WP5223_r140831/Complex/b5d84> .

<https://identifiers.org/chebi/CHEBI:18348>
        rdf:type            wp:DataNode , wp:Metabolite ;
        rdfs:label          "PtdIns(4,5)P2" ;
        dc:identifier       <https://identifiers.org/chebi/CHEBI:18348> ;
        dc:source           "ChEBI" ;
        dcterms:identifier  "CHEBI:18348" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP5223_r140831/WP/Interaction/idaba1c3ee> , <http://rdf.wikipathways.org/Pathway/WP5223_r140831/WP/Interaction/idc339a3c2> , <https://identifiers.org/wikipathways/WP5223_r140831> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:18348> ;
        wp:bdbKeggCompound  <https://identifiers.org/kegg.compound/C04637> ;
        wp:bdbLipidMaps     <https://identifiers.org/lipidmaps/LMGP08010005> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q28797894> , <http://www.wikidata.org/entity/Q130305193> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5223_r140831/DataNode/cdee8> ;
        owl:sameAs          <https://www.lipidmaps.org/rdf/LMGP08010005> ;
        foaf:page           <https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:18348> .

<http://rdf.wikipathways.org/Pathway/WP5223_r140831/WP/Interaction/id402880c8>
        rdf:type            wp:Interaction , wp:Stimulation , wp:DirectedInteraction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP5223_r140831> ;
        dcterms:references  <https://identifiers.org/pubmed/30420269> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5223_r140831/Interaction/id402880c8> ;
        wp:participants     <https://identifiers.org/ensembl/ENSG00000188219> , <https://identifiers.org/wikipathways/WP1471> ;
        wp:source           <https://identifiers.org/ensembl/ENSG00000188219> ;
        wp:target           <https://identifiers.org/wikipathways/WP1471> .

<http://rdf.wikipathways.org/Pathway/WP5223_r140831/WP/Interaction/ideb5a87e5>
        rdf:type            wp:DirectedInteraction , wp:Inhibition , wp:Interaction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP5223_r140831> ;
        dcterms:references  <https://identifiers.org/pubmed/20716133> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5223_r140831/Interaction/ideb5a87e5> ;
        wp:participants     <https://identifiers.org/ensembl/ENSG00000152102> , <https://identifiers.org/ensembl/ENSG00000168610> ;
        wp:source           <https://identifiers.org/ensembl/ENSG00000152102> ;
        wp:target           <https://identifiers.org/ensembl/ENSG00000168610> .

<http://rdf.wikipathways.org/Pathway/WP5223_r140831/ComplexBinding/b6ce7>
        rdf:type          wp:ComplexBinding , wp:Binding , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP5223_r140831> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP5223_r140831/Group/b6ce7> ;
        wp:participants   <https://identifiers.org/chebi/CHEBI:37565> , <https://identifiers.org/ensembl/ENSG00000161973> , <http://rdf.wikipathways.org/Pathway/WP5223_r140831/Complex/b6ce7> .

<http://rdf.wikipathways.org/Pathway/WP5223_r140831/Complex/bb663>
        rdf:type          wp:Complex , wp:DataNode ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP5223_r140831> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP5223_r140831/Group/bb663> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000067560> , <https://identifiers.org/chebi/CHEBI:37565> .

<https://identifiers.org/pubmed/10947987>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "10947987" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP5223_r140831/WP/Interaction/ide5306acd> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/10947987> .

<http://rdf.wikipathways.org/Pathway/WP5223_r140831/WP/Interaction/ide8483a1c>
        rdf:type            wp:DirectedInteraction , wp:Interaction , wp:Stimulation ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP5223_r140831> ;
        dcterms:references  <https://identifiers.org/pubmed/22771904> , <https://identifiers.org/pubmed/20716133> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP5223_r140831/Interaction/ide8483a1c> ;
        wp:participants     <https://identifiers.org/ensembl/ENSG00000152102> , <https://identifiers.org/ensembl/ENSG00000004897> ;
        wp:source           <https://identifiers.org/ensembl/ENSG00000152102> ;
        wp:target           <https://identifiers.org/ensembl/ENSG00000004897> .
