@prefix biopax:  <http://www.biopax.org/release/biopax-level3.owl#> .
@prefix cito:    <http://purl.org/spar/cito/> .
@prefix dc:      <http://purl.org/dc/elements/1.1/> .
@prefix dcterms: <http://purl.org/dc/terms/> .
@prefix foaf:    <http://xmlns.com/foaf/0.1/> .
@prefix freq:    <http://purl.org/cld/freq/> .
@prefix gpml:    <http://vocabularies.wikipathways.org/gpml#> .
@prefix obo:     <http://purl.obolibrary.org/obo/> .
@prefix owl:     <http://www.w3.org/2002/07/owl#> .
@prefix pav:     <http://purl.org/pav/> .
@prefix prov:    <http://www.w3.org/ns/prov#> .
@prefix rdf:     <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix rdfs:    <http://www.w3.org/2000/01/rdf-schema#> .
@prefix skos:    <http://www.w3.org/2004/02/skos/core#> .
@prefix void:    <http://rdfs.org/ns/void#> .
@prefix wp:      <http://vocabularies.wikipathways.org/wp#> .
@prefix wprdf:   <http://rdf.wikipathways.org/> .
@prefix xsd:     <http://www.w3.org/2001/XMLSchema#> .

<https://identifiers.org/pubmed/10224120>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "10224120" ;
        dcterms:isPartOf    <https://identifiers.org/ensembl/ENSG00000110711> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/10224120> .

<https://identifiers.org/pubmed/10398686>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "10398686" ;
        dcterms:isPartOf    <https://identifiers.org/ncbigene/1027> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/10398686> .

<http://rdf.wikipathways.org/Pathway/WP2586_r142469/ComplexBinding/bca0b>
        rdf:type          wp:ComplexBinding , wp:Binding , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2586_r142469> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2586_r142469/Group/bca0b> ;
        wp:participants   <https://identifiers.org/ncbigene/2033> , <https://identifiers.org/ncbigene/84722> , <http://rdf.wikipathways.org/Pathway/WP2586_r142469/Complex/bca0b> .

<http://rdf.wikipathways.org/Pathway/WP2586_r142469/WP/Interaction/idf8007aad>
        rdf:type            wp:Interaction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2586_r142469> ;
        dcterms:references  <https://identifiers.org/pubmed/9712901> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2586_r142469/Interaction/idf8007aad> ;
        wp:participants     <https://identifiers.org/uniprot/P06400> .

<https://identifiers.org/ncbigene/5594>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "MAPK1" ;
        dc:identifier       <https://identifiers.org/ncbigene/5594> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "5594" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2586_r142469> , <http://rdf.wikipathways.org/Pathway/WP2586_r142469/WP/Interaction/idacb2b077> , <http://rdf.wikipathways.org/Pathway/WP2586_r142469/WP/Interaction/idc77daae1> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000100030> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/5594> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/MAPK1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q1HBJ4> , <https://identifiers.org/uniprot/P28482> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2586_r142469/DataNode/fca81> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P28482> , <http://purl.uniprot.org/uniprot/Q1HBJ4> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/5594> .

<https://identifiers.org/ncbigene/1956>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "EGFR" ;
        dc:identifier       <https://identifiers.org/ncbigene/1956> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "1956" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2586_r142469> ;
        dcterms:references  <https://identifiers.org/pubmed/9504046> , <https://identifiers.org/pubmed/3266253> , <https://identifiers.org/pubmed/6095293> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000146648> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/1956> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/EGFR> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/C9JYS6> , <https://identifiers.org/uniprot/A0A8V8TPW8> , <https://identifiers.org/uniprot/Q504U8> , <https://identifiers.org/uniprot/P00533> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2586_r142469/DataNode/c9150> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A8V8TPW8> , <http://purl.uniprot.org/uniprot/Q504U8> , <http://purl.uniprot.org/uniprot/C9JYS6> , <http://purl.uniprot.org/uniprot/P00533> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/1956> .

<https://identifiers.org/ncbigene/4609>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "MYC" ;
        dc:identifier       <https://identifiers.org/ncbigene/4609> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "4609" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2586_r142469> ;
        dcterms:references  <https://identifiers.org/pubmed/11114727> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000136997> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/4609> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/MYC> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/P01106> , <https://identifiers.org/uniprot/Q14899> , <https://identifiers.org/uniprot/A0A494C1T8> , <https://identifiers.org/uniprot/Q16591> , <https://identifiers.org/uniprot/A0A0B4J1R1> , <https://identifiers.org/uniprot/H0YBG3> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2586_r142469/DataNode/ab635> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P01106> , <http://purl.uniprot.org/uniprot/A0A0B4J1R1> , <http://purl.uniprot.org/uniprot/Q16591> , <http://purl.uniprot.org/uniprot/Q14899> , <http://purl.uniprot.org/uniprot/H0YBG3> , <http://purl.uniprot.org/uniprot/A0A494C1T8> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/4609> .

<https://identifiers.org/pubmed/10777214>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "10777214" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2586_r142469/WP/Interaction/idb5568ae7> , <https://identifiers.org/ncbigene/17494212> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/10777214> .

<https://identifiers.org/pubmed/6095293>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "6095293" ;
        dcterms:isPartOf    <https://identifiers.org/ncbigene/1956> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/6095293> .

<https://identifiers.org/pubmed/22903824>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "22903824" ;
        dcterms:isPartOf    <https://identifiers.org/ncbigene/196> , <https://identifiers.org/ncbigene/405> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/22903824> .

<http://rdf.wikipathways.org/Pathway/WP2586_r142469/Complex/bca0b>
        rdf:type          wp:Complex , wp:DataNode ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2586_r142469> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2586_r142469/Group/bca0b> ;
        wp:participants   <https://identifiers.org/ncbigene/2033> , <https://identifiers.org/ncbigene/84722> .

<https://identifiers.org/pubmed/9704006>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "9704006" ;
        dcterms:isPartOf    <https://identifiers.org/ncbigene/405> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/9704006> .

<https://identifiers.org/pubmed/19366855>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "19366855" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2586_r142469/WP/Interaction/id7bd0c467> , <https://identifiers.org/ncbigene/5979> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/19366855> .

<https://identifiers.org/ncbigene/4780>
        rdf:type            wp:GeneProduct , wp:DataNode , wp:Rna ;
        rdfs:label          "NFE2L2" ;
        dc:identifier       <https://identifiers.org/ncbigene/4780> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "4780" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2586_r142469/Complex/b4164> , <https://identifiers.org/wikipathways/WP2586_r142469> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000116044> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/4780> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/NFE2L2> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A8V8TNS1> , <https://identifiers.org/uniprot/A0A8V8TN41> , <https://identifiers.org/uniprot/A0A8V8TN31> , <https://identifiers.org/uniprot/A0A8V8TNI6> , <https://identifiers.org/uniprot/A0A8V8TN51> , <https://identifiers.org/uniprot/A0A8V8TNM5> , <https://identifiers.org/uniprot/A0A8V8TPT8> , <https://identifiers.org/uniprot/A0A8V8TN14> , <https://identifiers.org/uniprot/A0A8V8TNQ8> , <https://identifiers.org/uniprot/A0A8V8TNJ6> , <https://identifiers.org/uniprot/C9J1A8> , <https://identifiers.org/uniprot/A0A8V8TN85> , <https://identifiers.org/uniprot/A0A8V8TPC8> , <https://identifiers.org/uniprot/K7EIW5> , <https://identifiers.org/uniprot/Q16236> , <https://identifiers.org/uniprot/C9J0Y1> , <https://identifiers.org/uniprot/A0A8V8TPA8> , <https://identifiers.org/uniprot/A0A8V8TPN5> , <https://identifiers.org/uniprot/A0A8V8TPM0> , <https://identifiers.org/uniprot/A0A8V8TQ20> , <https://identifiers.org/uniprot/A0A8V8TPL6> , <https://identifiers.org/uniprot/A0A8V8TN40> , <https://identifiers.org/uniprot/A0A8V8TPF4> , <https://identifiers.org/uniprot/A0A8V8TPX0> , <https://identifiers.org/uniprot/A0A8V8TND9> , <https://identifiers.org/uniprot/A0A8V8TNM0> , <https://identifiers.org/uniprot/K7ER33> , <https://identifiers.org/uniprot/H7C498> , <https://identifiers.org/uniprot/A0A8V8TPF0> , <https://identifiers.org/uniprot/A0A8V8TPI5> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2586_r142469/DataNode/b6a53> , <http://rdf.wikipathways.org/Pathway/WP2586_r142469/DataNode/edf9e> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A8V8TPC8> , <http://purl.uniprot.org/uniprot/A0A8V8TNQ8> , <http://purl.uniprot.org/uniprot/A0A8V8TNI6> , <http://purl.uniprot.org/uniprot/A0A8V8TPA8> , <http://purl.uniprot.org/uniprot/A0A8V8TN85> , <http://purl.uniprot.org/uniprot/A0A8V8TQ20> , <http://purl.uniprot.org/uniprot/A0A8V8TN31> , <http://purl.uniprot.org/uniprot/A0A8V8TNM5> , <http://purl.uniprot.org/uniprot/A0A8V8TPF0> , <http://purl.uniprot.org/uniprot/A0A8V8TPI5> , <http://purl.uniprot.org/uniprot/A0A8V8TNS1> , <http://purl.uniprot.org/uniprot/A0A8V8TPT8> , <http://purl.uniprot.org/uniprot/A0A8V8TPL6> , <http://purl.uniprot.org/uniprot/C9J0Y1> , <http://purl.uniprot.org/uniprot/K7EIW5> , <http://purl.uniprot.org/uniprot/A0A8V8TNJ6> , <http://purl.uniprot.org/uniprot/A0A8V8TN14> , <http://purl.uniprot.org/uniprot/H7C498> , <http://purl.uniprot.org/uniprot/A0A8V8TNM0> , <http://purl.uniprot.org/uniprot/A0A8V8TND9> , <http://purl.uniprot.org/uniprot/A0A8V8TPX0> , <http://purl.uniprot.org/uniprot/A0A8V8TPM0> , <http://purl.uniprot.org/uniprot/A0A8V8TN51> , <http://purl.uniprot.org/uniprot/C9J1A8> , <http://purl.uniprot.org/uniprot/A0A8V8TN41> , <http://purl.uniprot.org/uniprot/A0A8V8TPF4> , <http://purl.uniprot.org/uniprot/A0A8V8TN40> , <http://purl.uniprot.org/uniprot/K7ER33> , <http://purl.uniprot.org/uniprot/A0A8V8TPN5> , <http://purl.uniprot.org/uniprot/Q16236> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/4780> .

<http://rdf.wikipathways.org/Pathway/WP2586_r142469/WP/Interaction/a897d>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2586_r142469> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2586_r142469/Interaction/a897d> ;
        wp:participants   <https://identifiers.org/wikipathways/WP712> , <https://identifiers.org/ncbigene/1545> ;
        wp:source         <https://identifiers.org/ncbigene/1545> ;
        wp:target         <https://identifiers.org/wikipathways/WP712> .

<http://rdf.wikipathways.org/Pathway/WP2586_r142469/ComplexBinding/a8219>
        rdf:type          wp:Binding , wp:Interaction , wp:ComplexBinding ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2586_r142469> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2586_r142469/Group/a8219> ;
        wp:participants   <https://identifiers.org/ncbigene/2033> , <http://rdf.wikipathways.org/Pathway/WP2586_r142469/Complex/a8219> , <https://identifiers.org/ncbigene/8204> , <https://identifiers.org/ncbigene/4763> , <https://identifiers.org/ncbigene/9612> , <https://identifiers.org/ncbigene/135112> .

<https://identifiers.org/pubmed/18827440>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "18827440" ;
        dcterms:isPartOf    <https://identifiers.org/ncbigene/4023> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/18827440> .

<https://identifiers.org/pubmed/18089838>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "18089838" ;
        dcterms:isPartOf    <https://identifiers.org/wikidata/Q15322916> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/18089838> .

<http://rdf.wikipathways.org/Pathway/WP2586_r142469/WP/Interaction/idfdca4d95>
        rdf:type          wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2586_r142469> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2586_r142469/Interaction/idfdca4d95> .

<https://identifiers.org/wikipathways/WP254>
        rdf:type            wp:Pathway , wp:DataNode ;
        rdfs:label          "FAS / FAS-L (Apoptosis)" ;
        dc:identifier       <https://identifiers.org/wikipathways/WP254> ;
        dc:source           "WikiPathways" ;
        dcterms:identifier  "WP254" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2586_r142469> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2586_r142469/DataNode/f34fd> ;
        foaf:page           <https://www.wikipathways.org/instance/WP254> .

<http://rdf.wikipathways.org/Pathway/WP2586_r142469/Complex/a8219>
        rdf:type          wp:Complex , wp:DataNode ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2586_r142469> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2586_r142469/Group/a8219> ;
        wp:participants   <https://identifiers.org/ncbigene/9612> , <https://identifiers.org/ncbigene/2033> , <https://identifiers.org/ncbigene/135112> , <https://identifiers.org/ncbigene/8204> , <https://identifiers.org/ncbigene/4763> .

<http://rdf.wikipathways.org/Pathway/WP2586_r142469/ComplexBinding/e3e14>
        rdf:type                       wp:Interaction , wp:Binding , wp:ComplexBinding ;
        dcterms:bibliographicCitation  <https://identifiers.org/pubmed/10961990> ;
        dcterms:isPartOf               <https://identifiers.org/wikipathways/WP2586_r142469> ;
        wp:isAbout                     <http://rdf.wikipathways.org/Pathway/WP2586_r142469/Group/e3e14> ;
        wp:participants                <https://identifiers.org/ncbigene/196> , <https://identifiers.org/ensembl/ENSG00000110711> , <http://rdf.wikipathways.org/Pathway/WP2586_r142469/Complex/e3e14> , <https://identifiers.org/ncbigene/3320> .

<http://rdf.wikipathways.org/Pathway/WP2586_r142469/WP/Interaction/d1896>
        rdf:type          wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2586_r142469> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2586_r142469/Interaction/d1896> .

<https://identifiers.org/ncbigene/26291>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "FGF21" ;
        dc:identifier       <https://identifiers.org/ncbigene/26291> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "26291" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2586_r142469/Complex/b4164> , <https://identifiers.org/wikipathways/WP2586_r142469> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000105550> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/26291> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/FGF21> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q9NSA1> , <https://identifiers.org/uniprot/A0A7U3L5M7> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2586_r142469/DataNode/d3431> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A7U3L5M7> , <http://purl.uniprot.org/uniprot/Q9NSA1> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/26291> .

<https://identifiers.org/wikipathways/WP1539>
        rdf:type            wp:Pathway , wp:DataNode ;
        rdfs:label          "Angiogenesis" ;
        dc:identifier       <https://identifiers.org/wikipathways/WP1539> ;
        dc:source           "WikiPathways" ;
        dcterms:identifier  "WP1539" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2586_r142469/WP/Interaction/idbd129eca> , <https://identifiers.org/wikipathways/WP2586_r142469> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2586_r142469/DataNode/c3719> ;
        foaf:page           <https://www.wikipathways.org/instance/WP1539> .

<https://identifiers.org/pubmed/9712901>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "9712901" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2586_r142469/WP/Interaction/idf8007aad> , <https://identifiers.org/uniprot/P06400> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/9712901> .

<https://identifiers.org/pubmed/11097088>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "11097088" ;
        dcterms:isPartOf    <https://identifiers.org/chebi/CHEBI:33848> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/11097088> .

<https://identifiers.org/pubmed/12727795>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "12727795" ;
        dcterms:isPartOf    <https://identifiers.org/chebi/CHEBI:28119> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/12727795> .

<https://identifiers.org/pubmed/15322122>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "15322122" ;
        dcterms:isPartOf    <https://identifiers.org/ncbigene/3320> , <https://identifiers.org/ensembl/ENSG00000110711> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/15322122> .

<https://identifiers.org/ensembl/ENSG00000133703>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "KRAS" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000133703> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000133703" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2586_r142469> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000133703> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/3845> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/KRAS> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/G3V4K2> , <https://identifiers.org/uniprot/G3V5T7> , <https://identifiers.org/uniprot/L7RSL8> , <https://identifiers.org/uniprot/A0A024RAV5> , <https://identifiers.org/uniprot/A0A8I5KUB5> , <https://identifiers.org/uniprot/A0A8I5KYH6> , <https://identifiers.org/uniprot/A0A8I5KQU3> , <https://identifiers.org/uniprot/A0A8I5KR86> , <https://identifiers.org/uniprot/A0A8I5KXN3> , <https://identifiers.org/uniprot/P01116> , <https://identifiers.org/uniprot/A0A8I5KQ21> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q20969980> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2586_r142469/DataNode/cc14a> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A8I5KUB5> , <http://purl.uniprot.org/uniprot/L7RSL8> , <http://purl.uniprot.org/uniprot/P01116> , <http://purl.uniprot.org/uniprot/A0A8I5KXN3> , <http://purl.uniprot.org/uniprot/G3V4K2> , <http://purl.uniprot.org/uniprot/A0A8I5KYH6> , <http://purl.uniprot.org/uniprot/A0A8I5KR86> , <http://purl.uniprot.org/uniprot/A0A024RAV5> , <http://purl.uniprot.org/uniprot/A0A8I5KQU3> , <http://purl.uniprot.org/uniprot/A0A8I5KQ21> , <http://purl.uniprot.org/uniprot/G3V5T7> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000133703> .

<https://identifiers.org/pubmed/956169>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "956169" ;
        dcterms:isPartOf    <https://identifiers.org/chebi/CHEBI:28119> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/956169> .

<https://identifiers.org/ensembl/ENSG00000132155>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "RAF1" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000132155> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000132155" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2586_r142469> , <http://rdf.wikipathways.org/Pathway/WP2586_r142469/WP/Interaction/idfb358ab4> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000132155> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/5894> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/RAF1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A8I5KSM4> , <https://identifiers.org/uniprot/A0A8I5KWS9> , <https://identifiers.org/uniprot/A0A8I5KQV4> , <https://identifiers.org/uniprot/A0A8I5KSB0> , <https://identifiers.org/uniprot/A0A8I5KTK4> , <https://identifiers.org/uniprot/A0A8I5KSV6> , <https://identifiers.org/uniprot/P04049> , <https://identifiers.org/uniprot/H7C155> , <https://identifiers.org/uniprot/A0A8I5KYC4> , <https://identifiers.org/uniprot/A0A8I5KR46> , <https://identifiers.org/uniprot/A0A8I5KWA9> , <https://identifiers.org/uniprot/A0A8I5QJG5> , <https://identifiers.org/uniprot/A0A8I5KS16> , <https://identifiers.org/uniprot/A0A8I5KSI1> , <https://identifiers.org/uniprot/A0A8I5KTA5> , <https://identifiers.org/uniprot/A0A0B4J1W9> , <https://identifiers.org/uniprot/A0A8I5QKZ6> , <https://identifiers.org/uniprot/A0A8I5KW44> , <https://identifiers.org/uniprot/A0A8I5KRD1> , <https://identifiers.org/uniprot/A0A8I5QKU8> , <https://identifiers.org/uniprot/L7RRS6> , <https://identifiers.org/uniprot/A0A8I5KQ33> , <https://identifiers.org/uniprot/A0A0S2Z559> , <https://identifiers.org/uniprot/A0A8I5KYP5> , <https://identifiers.org/uniprot/A0A8I5KWF7> , <https://identifiers.org/uniprot/A0A8I5KUW4> , <https://identifiers.org/uniprot/A0A8I5KT32> , <https://identifiers.org/uniprot/A0A8I5KX50> , <https://identifiers.org/uniprot/A0A0S2Z4L5> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q14903573> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2586_r142469/DataNode/e5823> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A8I5KTK4> , <http://purl.uniprot.org/uniprot/A0A8I5KQ33> , <http://purl.uniprot.org/uniprot/A0A8I5QKZ6> , <http://purl.uniprot.org/uniprot/A0A8I5KYP5> , <http://purl.uniprot.org/uniprot/H7C155> , <http://purl.uniprot.org/uniprot/A0A8I5KSI1> , <http://purl.uniprot.org/uniprot/A0A8I5KWA9> , <http://purl.uniprot.org/uniprot/A0A0S2Z559> , <http://purl.uniprot.org/uniprot/A0A8I5KSM4> , <http://purl.uniprot.org/uniprot/A0A8I5KSV6> , <http://purl.uniprot.org/uniprot/A0A8I5KWF7> , <http://purl.uniprot.org/uniprot/A0A8I5KUW4> , <http://purl.uniprot.org/uniprot/A0A8I5QJG5> , <http://purl.uniprot.org/uniprot/A0A0S2Z4L5> , <http://purl.uniprot.org/uniprot/A0A0B4J1W9> , <http://purl.uniprot.org/uniprot/L7RRS6> , <http://purl.uniprot.org/uniprot/A0A8I5KYC4> , <http://purl.uniprot.org/uniprot/A0A8I5KS16> , <http://purl.uniprot.org/uniprot/P04049> , <http://purl.uniprot.org/uniprot/A0A8I5KTA5> , <http://purl.uniprot.org/uniprot/A0A8I5KRD1> , <http://purl.uniprot.org/uniprot/A0A8I5KT32> , <http://purl.uniprot.org/uniprot/A0A8I5QKU8> , <http://purl.uniprot.org/uniprot/A0A8I5KWS9> , <http://purl.uniprot.org/uniprot/A0A8I5KSB0> , <http://purl.uniprot.org/uniprot/A0A8I5KR46> , <http://purl.uniprot.org/uniprot/A0A8I5KX50> , <http://purl.uniprot.org/uniprot/A0A8I5KW44> , <http://purl.uniprot.org/uniprot/A0A8I5KQV4> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000132155> .

<https://identifiers.org/wikipathways/WP1910>
        rdf:type            wp:DataNode , wp:Pathway ;
        rdfs:label          "EGFR pathway" ;
        dc:identifier       <https://identifiers.org/wikipathways/WP1910> ;
        dc:source           "WikiPathways" ;
        dcterms:identifier  "WP1910" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2586_r142469/WP/Interaction/f695c> , <https://identifiers.org/wikipathways/WP2586_r142469> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2586_r142469/DataNode/e867d> ;
        foaf:page           <https://www.wikipathways.org/instance/WP1910> .

<https://identifiers.org/wikipathways/WP712>
        rdf:type            wp:DataNode , wp:Pathway ;
        rdfs:label          "Modulation of estrogen receptor signaling" ;
        dc:identifier       <https://identifiers.org/wikipathways/WP712> ;
        dc:source           "WikiPathways" ;
        dcterms:identifier  "WP712" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2586_r142469> , <http://rdf.wikipathways.org/Pathway/WP2586_r142469/WP/Interaction/b5103> , <http://rdf.wikipathways.org/Pathway/WP2586_r142469/WP/Interaction/a897d> , <http://rdf.wikipathways.org/Pathway/WP2586_r142469/WP/Interaction/a321a> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2586_r142469/DataNode/a5018> ;
        foaf:page           <https://www.wikipathways.org/instance/WP712> .

<http://rdf.wikipathways.org/Pathway/WP2586_r142469/ComplexBinding/c3bdd>
        rdf:type          wp:ComplexBinding , wp:Binding , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2586_r142469> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2586_r142469/Group/c3bdd> ;
        wp:participants   <https://identifiers.org/ncbigene/6714> , <https://identifiers.org/ncbigene/11140> , <https://identifiers.org/ncbigene/3320> , <http://rdf.wikipathways.org/Pathway/WP2586_r142469/Complex/c3bdd> .

<https://identifiers.org/ncbigene/4023>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "LPL" ;
        dc:identifier       <https://identifiers.org/ncbigene/4023> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "4023" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2586_r142469> , <http://rdf.wikipathways.org/Pathway/WP2586_r142469/Complex/b4164> ;
        dcterms:references  <https://identifiers.org/pubmed/18827440> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000175445> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/4023> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/LPL> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/P06858> , <https://identifiers.org/uniprot/A0A1B1RVA9> , <https://identifiers.org/uniprot/E5RHN7> , <https://identifiers.org/uniprot/A0A3B3IT60> , <https://identifiers.org/uniprot/E5RJI0> , <https://identifiers.org/uniprot/E5RJZ4> , <https://identifiers.org/uniprot/E7EW14> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2586_r142469/DataNode/a97b0> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A1B1RVA9> , <http://purl.uniprot.org/uniprot/E5RJI0> , <http://purl.uniprot.org/uniprot/E5RHN7> , <http://purl.uniprot.org/uniprot/A0A3B3IT60> , <http://purl.uniprot.org/uniprot/E7EW14> , <http://purl.uniprot.org/uniprot/P06858> , <http://purl.uniprot.org/uniprot/E5RJZ4> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/4023> .

<http://rdf.wikipathways.org/Pathway/WP2586_r142469/Complex/c3bdd>
        rdf:type          wp:Complex , wp:DataNode ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2586_r142469> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2586_r142469/Group/c3bdd> ;
        wp:participants   <https://identifiers.org/ncbigene/6714> , <https://identifiers.org/ncbigene/11140> , <https://identifiers.org/ncbigene/3320> .

<http://rdf.wikipathways.org/Pathway/WP2586_r142469/WP/Interaction/f1509>
        rdf:type          wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2586_r142469> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2586_r142469/Interaction/f1509> ;
        wp:participants   <https://identifiers.org/ncbigene/1545> , <https://identifiers.org/ncbigene/1544> .

<https://identifiers.org/ncbigene/405>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "ARNT" ;
        dc:identifier       <https://identifiers.org/ncbigene/405> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "405" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2586_r142469> ;
        dcterms:references  <https://identifiers.org/pubmed/22903824> , <https://identifiers.org/pubmed/9704006> , <https://identifiers.org/pubmed/8396713> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000143437> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/405> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/ARNT> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A6NGV6> , <https://identifiers.org/uniprot/P27540> , <https://identifiers.org/uniprot/D6RDB3> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2586_r142469/DataNode/b4ed1> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/D6RDB3> , <http://purl.uniprot.org/uniprot/P27540> , <http://purl.uniprot.org/uniprot/A6NGV6> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/405> .

<http://rdf.wikipathways.org/Pathway/WP2586_r142469/WP/Interaction/a321a>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2586_r142469> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2586_r142469/Interaction/a321a> ;
        wp:participants   <https://identifiers.org/wikipathways/WP712> , <https://identifiers.org/ncbigene/1544> ;
        wp:source         <https://identifiers.org/ncbigene/1544> ;
        wp:target         <https://identifiers.org/wikipathways/WP712> .

<http://rdf.wikipathways.org/Pathway/WP2586_r142469/WP/Interaction/id741ef049>
        rdf:type          wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2586_r142469> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2586_r142469/Interaction/id741ef049> ;
        wp:participants   <https://identifiers.org/ncbigene/1027> .

<http://rdf.wikipathways.org/Pathway/WP2586_r142469/WP/Interaction/idacb2b077>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2586_r142469> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2586_r142469/Interaction/idacb2b077> ;
        wp:participants   <https://identifiers.org/ncbigene/5594> , <https://identifiers.org/ensembl/ENSG00000169032> ;
        wp:source         <https://identifiers.org/ensembl/ENSG00000169032> ;
        wp:target         <https://identifiers.org/ncbigene/5594> .

<https://identifiers.org/ncbigene/6714>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "SRC" ;
        dc:identifier       <https://identifiers.org/ncbigene/6714> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "6714" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2586_r142469> , <http://rdf.wikipathways.org/Pathway/WP2586_r142469/Complex/c3bdd> ;
        dcterms:references  <https://identifiers.org/pubmed/9380030> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000197122> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/6714> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/SRC> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A8I5KYU4> , <https://identifiers.org/uniprot/P12931> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2586_r142469/DataNode/b426e> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P12931> , <http://purl.uniprot.org/uniprot/A0A8I5KYU4> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/6714> .

<https://identifiers.org/chebi/CHEBI:28119>
        rdf:type            wp:DataNode , wp:Metabolite ;
        rdfs:label          "TCDD" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/HGUFODBRKLSHSI-UHFFFAOYSA-N> ;
        dc:identifier       <https://identifiers.org/chebi/CHEBI:28119> ;
        dc:source           "ChEBI" ;
        dcterms:identifier  "CHEBI:28119" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2586_r142469> , <http://rdf.wikipathways.org/Pathway/WP2586_r142469/WP/Interaction/id4018eca7> ;
        dcterms:references  <https://identifiers.org/pubmed/956169> , <https://identifiers.org/pubmed/19474220> , <https://identifiers.org/pubmed/12727795> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:28119> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/14865> ;
        wp:bdbHmdb          <https://identifiers.org/hmdb/HMDB0258755> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/HGUFODBRKLSHSI-UHFFFAOYSA-N> ;
        wp:bdbKeggCompound  <https://identifiers.org/kegg.compound/C07557> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID15625> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q52822> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2586_r142469/DataNode/ea90f> , <http://rdf.wikipathways.org/Pathway/WP2586_r142469/DataNode/c3a80> ;
        foaf:page           <https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:28119> .

<https://identifiers.org/ncbigene/135112>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "NCOA7" ;
        dc:identifier       <https://identifiers.org/ncbigene/135112> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "135112" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2586_r142469/Complex/a8219> , <https://identifiers.org/wikipathways/WP2586_r142469> ;
        dcterms:references  <https://identifiers.org/pubmed/10395741> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000111912> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/135112> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/NCOA7> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/H0Y6T0> , <https://identifiers.org/uniprot/Q5TF96> , <https://identifiers.org/uniprot/H0Y5F6> , <https://identifiers.org/uniprot/Q5TF97> , <https://identifiers.org/uniprot/Q5TF98> , <https://identifiers.org/uniprot/Q8NI08> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2586_r142469/DataNode/f147b> , <http://rdf.wikipathways.org/Pathway/WP2586_r142469/DataNode/cdf5c> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q8NI08> , <http://purl.uniprot.org/uniprot/H0Y5F6> , <http://purl.uniprot.org/uniprot/Q5TF98> , <http://purl.uniprot.org/uniprot/Q5TF96> , <http://purl.uniprot.org/uniprot/Q5TF97> , <http://purl.uniprot.org/uniprot/H0Y6T0> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/135112> .

<http://rdf.wikipathways.org/Pathway/WP2586_r142469/ComplexBinding/b4164>
        rdf:type          wp:ComplexBinding , wp:Interaction , wp:Binding ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2586_r142469> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2586_r142469/Group/b4164> ;
        wp:participants   <https://identifiers.org/ncbigene/948> , <https://identifiers.org/ncbigene/1543> , <http://rdf.wikipathways.org/Pathway/WP2586_r142469/Complex/b4164> , <https://identifiers.org/ncbigene/4023> , <https://identifiers.org/ncbigene/26291> , <https://identifiers.org/ncbigene/4780> .

<https://identifiers.org/pubmed/10074425>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "10074425" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2586_r142469/WP/Interaction/faf4e> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/10074425> .

<https://identifiers.org/pubmed/2843537>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "2843537" ;
        dcterms:isPartOf    <https://identifiers.org/ncbigene/3320> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/2843537> .

<https://identifiers.org/ncbigene/11140>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "CDC37" ;
        dc:identifier       <https://identifiers.org/ncbigene/11140> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "11140" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2586_r142469/Complex/c3bdd> , <https://identifiers.org/wikipathways/WP2586_r142469> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000105401> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/11140> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/CDC37> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/K7EKQ2> , <https://identifiers.org/uniprot/A0A024R7B7> , <https://identifiers.org/uniprot/Q16543> , <https://identifiers.org/uniprot/K7EQA9> , <https://identifiers.org/uniprot/K7EL68> , <https://identifiers.org/uniprot/K7EIU0> , <https://identifiers.org/uniprot/K7EJ06> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2586_r142469/DataNode/bd60d> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/K7EQA9> , <http://purl.uniprot.org/uniprot/K7EKQ2> , <http://purl.uniprot.org/uniprot/Q16543> , <http://purl.uniprot.org/uniprot/K7EIU0> , <http://purl.uniprot.org/uniprot/A0A024R7B7> , <http://purl.uniprot.org/uniprot/K7EJ06> , <http://purl.uniprot.org/uniprot/K7EL68> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/11140> .

<http://rdf.wikipathways.org/Pathway/WP2586_r142469/ComplexBinding/cf474>
        rdf:type                       wp:Interaction , wp:ComplexBinding , wp:Binding ;
        dcterms:bibliographicCitation  <https://identifiers.org/pubmed/19474220> ;
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        wp:isAbout                     <http://rdf.wikipathways.org/Pathway/WP2586_r142469/Group/cf474> ;
        wp:participants                <https://identifiers.org/ncbigene/1728> , <https://identifiers.org/ncbigene/27306> , <https://identifiers.org/ncbigene/2729> , <http://rdf.wikipathways.org/Pathway/WP2586_r142469/Complex/cf474> .

<http://rdf.wikipathways.org/Pathway/WP2586_r142469/Complex/b4164>
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        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2586_r142469/Group/b4164> ;
        wp:participants   <https://identifiers.org/ncbigene/948> , <https://identifiers.org/ncbigene/4780> , <https://identifiers.org/ncbigene/4023> , <https://identifiers.org/ncbigene/1543> , <https://identifiers.org/ncbigene/26291> .

<http://rdf.wikipathways.org/Pathway/WP2586_r142469/WP/Interaction/id421faf29>
        rdf:type          wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2586_r142469> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2586_r142469/Interaction/id421faf29> ;
        wp:participants   <https://identifiers.org/ncbigene/8204> .

<http://rdf.wikipathways.org/Pathway/WP2586_r142469/Complex/cf474>
        rdf:type                       wp:Complex , wp:DataNode ;
        dcterms:bibliographicCitation  <https://identifiers.org/pubmed/19474220> ;
        dcterms:isPartOf               <https://identifiers.org/wikipathways/WP2586_r142469> ;
        dcterms:references             <https://identifiers.org/pubmed/19474220> ;
        wp:isAbout                     <http://rdf.wikipathways.org/Pathway/WP2586_r142469/Group/cf474> ;
        wp:participants                <https://identifiers.org/ncbigene/2729> , <https://identifiers.org/ncbigene/1728> , <https://identifiers.org/ncbigene/27306> .

<http://rdf.wikipathways.org/Pathway/WP2586_r142469/WP/Interaction/idac09c4e3>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2586_r142469> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2586_r142469/Interaction/idac09c4e3> ;
        wp:participants   <https://identifiers.org/ncbigene/57491> , <https://identifiers.org/ncbigene/1543> ;
        wp:source         <https://identifiers.org/ncbigene/1543> ;
        wp:target         <https://identifiers.org/ncbigene/57491> .

<https://identifiers.org/ncbigene/1728>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "NQO1" ;
        dc:identifier       <https://identifiers.org/ncbigene/1728> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "1728" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2586_r142469/Complex/cf474> , <https://identifiers.org/wikipathways/WP2586_r142469> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000181019> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/1728> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/NQO1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/H3BRK3> , <https://identifiers.org/uniprot/H3BNV2> , <https://identifiers.org/uniprot/P15559> , <https://identifiers.org/uniprot/B4DLR8> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2586_r142469/DataNode/a9a74> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/H3BNV2> , <http://purl.uniprot.org/uniprot/H3BRK3> , <http://purl.uniprot.org/uniprot/P15559> , <http://purl.uniprot.org/uniprot/B4DLR8> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/1728> .

<http://rdf.wikipathways.org/Pathway/WP2586_r142469/WP/Interaction/idff773eff>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2586_r142469> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2586_r142469/Interaction/idff773eff> ;
        wp:participants   <https://identifiers.org/ncbigene/5325> , <https://identifiers.org/ensembl/ENSG00000110711> ;
        wp:source         <https://identifiers.org/ensembl/ENSG00000110711> ;
        wp:target         <https://identifiers.org/ncbigene/5325> .

<https://doi.org/10.1021%2Facs.jproteome.7b00501>
        rdf:type            wp:PublicationReference ;
        dc:source           "DOI" ;
        dcterms:identifier  "10.1021/acs.jproteome.7b00501" ;
        cito:cites          <https://identifiers.org/wikipathways/WP2586> .

<http://rdf.wikipathways.org/Pathway/WP2586_r142469/WP/Interaction/idb5568ae7>
        rdf:type            wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2586_r142469> ;
        dcterms:references  <https://identifiers.org/pubmed/10777214> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2586_r142469/Interaction/idb5568ae7> ;
        wp:participants     <https://identifiers.org/ncbigene/17494212> , <https://identifiers.org/ensembl/ENSG00000110711> ;
        wp:source           <https://identifiers.org/ensembl/ENSG00000110711> ;
        wp:target           <https://identifiers.org/ncbigene/17494212> .

<http://rdf.wikipathways.org/Pathway/WP2586_r142469/WP/Interaction/b5103>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2586_r142469> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2586_r142469/Interaction/b5103> ;
        wp:participants   <https://identifiers.org/wikipathways/WP712> , <https://identifiers.org/ncbigene/1543> ;
        wp:source         <https://identifiers.org/ncbigene/1543> ;
        wp:target         <https://identifiers.org/wikipathways/WP712> .

<http://rdf.wikipathways.org/Pathway/WP2586_r142469/WP/Interaction/idc40b6454>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2586_r142469> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2586_r142469/Interaction/idc40b6454> ;
        wp:participants   <https://identifiers.org/ncbigene/5925> , <https://identifiers.org/ncbigene/1017> ;
        wp:source         <https://identifiers.org/ncbigene/1017> ;
        wp:target         <https://identifiers.org/ncbigene/5925> .

<https://identifiers.org/pubmed/11114727>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "11114727" ;
        dcterms:isPartOf    <https://identifiers.org/ncbigene/4609> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/11114727> .

<https://identifiers.org/pubmed/19574409>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "19574409" ;
        dcterms:isPartOf    <https://identifiers.org/ncbigene/2099> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/19574409> .

<https://identifiers.org/ncbigene/2729>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "GCLC" ;
        dc:identifier       <https://identifiers.org/ncbigene/2729> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "2729" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2586_r142469> , <http://rdf.wikipathways.org/Pathway/WP2586_r142469/Complex/cf474> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000001084> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/2729> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/GCLC> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/D6RGF8> , <https://identifiers.org/uniprot/A0A0C4DGB2> , <https://identifiers.org/uniprot/P48506> , <https://identifiers.org/uniprot/D6RIT4> , <https://identifiers.org/uniprot/B4E2I4> , <https://identifiers.org/uniprot/E1CEI4> , <https://identifiers.org/uniprot/A0A2R8Y648> , <https://identifiers.org/uniprot/Q14TF0> , <https://identifiers.org/uniprot/A0A2R8YEL6> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2586_r142469/DataNode/e6a72> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/E1CEI4> , <http://purl.uniprot.org/uniprot/A0A2R8YEL6> , <http://purl.uniprot.org/uniprot/D6RIT4> , <http://purl.uniprot.org/uniprot/P48506> , <http://purl.uniprot.org/uniprot/Q14TF0> , <http://purl.uniprot.org/uniprot/A0A0C4DGB2> , <http://purl.uniprot.org/uniprot/D6RGF8> , <http://purl.uniprot.org/uniprot/A0A2R8Y648> , <http://purl.uniprot.org/uniprot/B4E2I4> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/2729> .

<https://identifiers.org/ncbigene/6346>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "CCL1" ;
        dc:identifier       <https://identifiers.org/ncbigene/6346> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "6346" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2586_r142469> ;
        dcterms:references  <https://identifiers.org/pubmed/16679317> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000108702> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/6346> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/CCL1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/P22362> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2586_r142469/DataNode/a8343> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P22362> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/6346> .

<https://identifiers.org/pmc/PMC10913609>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed Central" ;
        dcterms:identifier  "PMC10913609" ;
        cito:cites          <https://identifiers.org/wikipathways/WP2586> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/PMC10913609> .

<http://rdf.wikipathways.org/Pathway/WP2586_r142469/ComplexBinding/cdac9>
        rdf:type          wp:ComplexBinding , wp:Binding , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2586_r142469> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2586_r142469/Group/cdac9> ;
        wp:participants   <https://identifiers.org/ncbigene/4790> , <https://identifiers.org/ncbigene/5970> , <http://rdf.wikipathways.org/Pathway/WP2586_r142469/Complex/cdac9> .

<https://identifiers.org/ncbigene/1544>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "CYP1A2" ;
        dc:identifier       <https://identifiers.org/ncbigene/1544> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "1544" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2586_r142469/WP/Interaction/id8cff4ef7> , <http://rdf.wikipathways.org/Pathway/WP2586_r142469/WP/Interaction/a321a> , <https://identifiers.org/wikipathways/WP2586_r142469> , <http://rdf.wikipathways.org/Pathway/WP2586_r142469/WP/Interaction/f1509> , <http://rdf.wikipathways.org/Pathway/WP2586_r142469/WP/Interaction/a5d40> ;
        dcterms:references  <https://identifiers.org/pubmed/8120057> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000140505> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/1544> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/CYP1A2> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/P05177> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2586_r142469/DataNode/a80d6> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P05177> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/1544> .

<https://identifiers.org/ensembl/ENSG00000174775>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "HRAS" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000174775> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000174775" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2586_r142469> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000174775> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/3265> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/HRAS> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/P01112> , <https://identifiers.org/uniprot/A0A804HJ06> , <https://identifiers.org/uniprot/X5D945> , <https://identifiers.org/uniprot/A0A804HKM6> , <https://identifiers.org/uniprot/A0A8C8MQR2> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2586_r142469/DataNode/b0732> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/X5D945> , <http://purl.uniprot.org/uniprot/P01112> , <http://purl.uniprot.org/uniprot/A0A804HJ06> , <http://purl.uniprot.org/uniprot/A0A804HKM6> , <http://purl.uniprot.org/uniprot/A0A8C8MQR2> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000174775> .

<http://rdf.wikipathways.org/Pathway/WP2586_r142469/Complex/cdac9>
        rdf:type          wp:Complex , wp:DataNode ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2586_r142469> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2586_r142469/Group/cdac9> ;
        wp:participants   <https://identifiers.org/ncbigene/4790> , <https://identifiers.org/ncbigene/5970> .

<http://rdf.wikipathways.org/Pathway/WP2586_r142469/ComplexBinding/cf6c8>
        rdf:type          wp:ComplexBinding , wp:Binding , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2586_r142469> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2586_r142469/Group/cf6c8> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000110711> , <https://identifiers.org/ncbigene/196> , <https://identifiers.org/ncbigene/3320> , <http://rdf.wikipathways.org/Pathway/WP2586_r142469/Complex/cf6c8> .

<https://identifiers.org/ncbigene/5979>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "RET" ;
        dc:identifier       <https://identifiers.org/ncbigene/5979> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "5979" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2586_r142469/WP/Interaction/id7bd0c467> , <https://identifiers.org/wikipathways/WP2586_r142469> ;
        dcterms:references  <https://identifiers.org/pubmed/19366855> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000165731> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/5979> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/RET> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A087WWB1> , <https://identifiers.org/uniprot/A0A024R7T2> , <https://identifiers.org/uniprot/A0A5F9ZHB7> , <https://identifiers.org/uniprot/C9JYL6> , <https://identifiers.org/uniprot/P07949> , <https://identifiers.org/uniprot/A0A804HIK7> , <https://identifiers.org/uniprot/A0A1W2PPN7> , <https://identifiers.org/uniprot/A0A804HL71> , <https://identifiers.org/uniprot/A0A5F9ZHR6> , <https://identifiers.org/uniprot/A0A1W2PSA1> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2586_r142469/DataNode/eccb3> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/C9JYL6> , <http://purl.uniprot.org/uniprot/A0A1W2PSA1> , <http://purl.uniprot.org/uniprot/A0A1W2PPN7> , <http://purl.uniprot.org/uniprot/A0A024R7T2> , <http://purl.uniprot.org/uniprot/A0A5F9ZHB7> , <http://purl.uniprot.org/uniprot/A0A804HL71> , <http://purl.uniprot.org/uniprot/A0A087WWB1> , <http://purl.uniprot.org/uniprot/P07949> , <http://purl.uniprot.org/uniprot/A0A5F9ZHR6> , <http://purl.uniprot.org/uniprot/A0A804HIK7> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/5979> .

<http://rdf.wikipathways.org/Pathway/WP2586_r142469/WP/Interaction/c9443>
        rdf:type            wp:Interaction , wp:TranscriptionTranslation , wp:DirectedInteraction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2586_r142469> ;
        dcterms:references  <https://identifiers.org/pubmed/18336843> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2586_r142469/Interaction/c9443> ;
        wp:participants     <https://identifiers.org/ncbigene/1545> , <https://identifiers.org/ncbigene/7124> ;
        wp:source           <https://identifiers.org/ncbigene/7124> ;
        wp:target           <https://identifiers.org/ncbigene/1545> .

<http://rdf.wikipathways.org/Pathway/WP2586_r142469/Complex/cf6c8>
        rdf:type          wp:Complex , wp:DataNode ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2586_r142469> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2586_r142469/Group/cf6c8> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000110711> , <https://identifiers.org/ncbigene/196> , <https://identifiers.org/ncbigene/3320> .

<https://identifiers.org/wikipathways/WP2586_r142469>
        rdf:type               skos:Collection , wp:Pathway ;
        dc:identifier          <https://identifiers.org/wikipathways/WP2586> ;
        dc:source              "WikiPathways" ;
        dc:title               "Aryl hydrocarbon receptor response to main mediators PAH and TCDD"@en ;
        dcterms:description    "The Aryl Hydrocarbon receptor (AhR) is ligand activated transcription factor that regulates wide spectrum of gene expression. The main mediator of AhR is 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) or polycyclic aromatic hydrocarbons which are widespread environmental pollutant causing a variety of severe health effects, e.g. immunosuppression, carcinogenesis and hepatotoxicity. \n\nAhR is a member of basic helix-loop-helix-Per-Arnt-Sim (bHLH-PAS) superfamily of transcription factors. In the absence of ligand, the AhR can be found in the cytosol, bound to a dimer of the heat shock protein of 90 kDa (Hsp90) and the immunophilin-like protein, AIP (also known as XAP2 and ARA9). Upon ligand binding, the AHR translocates to the nucleus and binds with ARNT. The AHR/ARNT heterodimer binds to xenobiotic response elements and regulates a diverse set of genes.\n\nProteins on this pathway have targeted assays available via the [CPTAC Assay Portal](https://assays.cancer.gov/available_assays?wp_id=WP2586)." ;
        dcterms:identifier     "WP2586" ;
        cito:cites             <https://identifiers.org/pubmed/8120057> , <https://identifiers.org/pubmed/9488039> , <https://identifiers.org/pubmed/956169> , <https://identifiers.org/pubmed/8396713> , <https://identifiers.org/pubmed/11502724> , <https://identifiers.org/pubmed/2843537> , <https://identifiers.org/pubmed/19255421> , <https://identifiers.org/pubmed/16679317> , <https://identifiers.org/pubmed/19574409> , <https://identifiers.org/pubmed/18089838> , <https://identifiers.org/pubmed/10961990> , <https://identifiers.org/pubmed/19474220> , <https://identifiers.org/pubmed/9704006> , <https://identifiers.org/pubmed/23512538> , <https://identifiers.org/pubmed/19617630> , <https://identifiers.org/pubmed/1844873> , <https://identifiers.org/pubmed/19203995> , <https://identifiers.org/pubmed/15322122> , <https://identifiers.org/pubmed/6095293> , <https://identifiers.org/pubmed/14597617> , <https://identifiers.org/pubmed/17934341> , <https://identifiers.org/pubmed/22903824> , <https://identifiers.org/pubmed/10398686> , <https://identifiers.org/pubmed/9380030> , <https://identifiers.org/pubmed/8910454> , <https://identifiers.org/pubmed/22659247> , <https://identifiers.org/pubmed/11259609> , <https://identifiers.org/pubmed/18336843> , <https://identifiers.org/pubmed/19366855> , <https://identifiers.org/pubmed/11097088> , <https://identifiers.org/pubmed/12727795> , <https://identifiers.org/pubmed/10620335> , <https://identifiers.org/pubmed/21856752> , <https://identifiers.org/pubmed/9504046> , <https://identifiers.org/pubmed/11114727> , <https://identifiers.org/pubmed/10777214> , <https://identifiers.org/pubmed/10224120> , <https://identifiers.org/pubmed/19158084> , <https://identifiers.org/pubmed/10074425> , <https://identifiers.org/pubmed/3266253> , <https://identifiers.org/pubmed/9712901> , <https://identifiers.org/pubmed/12223212> , <https://identifiers.org/pubmed/18827440> , <https://identifiers.org/pubmed/10395741> ;
        wp:isAbout             <http://rdf.wikipathways.org/Pathway/WP2586_r142469> ;
        wp:ontologyTag         obo:PW_0000004 , wp:Curation:ONTOX , wp:Curation:AnalysisCollection ;
        wp:organism            obo:NCBITaxon_9606 ;
        wp:organismName        "Homo sapiens" ;
        wp:pathwayOntologyTag  obo:PW_0000004 ;
        foaf:img               <https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=png&pwTitle=Pathway:WP2586&oldid=142469> , <https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=svg&pwTitle=Pathway:WP2586&oldid=142469> ;
        foaf:page              <http://www.wikipathways.org/instance/WP2586_r142469> .

<https://identifiers.org/pubmed/8120057>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "8120057" ;
        dcterms:isPartOf    <https://identifiers.org/ncbigene/1544> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/8120057> .

<http://rdf.wikipathways.org/Pathway/WP2586_r142469/WP/Interaction/idfb358ab4>
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        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2586_r142469/Interaction/idfb358ab4> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000169032> , <https://identifiers.org/ensembl/ENSG00000132155> ;
        wp:source         <https://identifiers.org/ensembl/ENSG00000132155> ;
        wp:target         <https://identifiers.org/ensembl/ENSG00000169032> .

<https://identifiers.org/ncbigene/1026>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "CDKN1A" ;
        dc:identifier       <https://identifiers.org/ncbigene/1026> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "1026" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2586_r142469/WP/Interaction/id72845f06> , <https://identifiers.org/wikipathways/WP2586_r142469> , <http://rdf.wikipathways.org/Pathway/WP2586_r142469/WP/Interaction/id9f884584> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000124762> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/1026> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/CDKN1A> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/P38936> , <https://identifiers.org/uniprot/A0A024RCX5> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2586_r142469/DataNode/f841e> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P38936> , <http://purl.uniprot.org/uniprot/A0A024RCX5> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/1026> .

<http://rdf.wikipathways.org/Pathway/WP2586_r142469/ComplexBinding/df20e>
        rdf:type          wp:ComplexBinding , wp:Interaction , wp:Binding ;
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        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2586_r142469/Group/df20e> ;
        wp:participants   <https://identifiers.org/ncbigene/2033> , <https://identifiers.org/ncbigene/4790> , <https://identifiers.org/ncbigene/84722> , <http://rdf.wikipathways.org/Pathway/WP2586_r142469/Complex/df20e> , <https://identifiers.org/ncbigene/5970> .

<https://identifiers.org/ensembl/ENSG00000110711>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "AIP" , "P23" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000110711> ;
        dc:source           "Ensembl" ;
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        dcterms:references  <https://identifiers.org/pubmed/10224120> , <https://identifiers.org/pubmed/15322122> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000110711> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/9049> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/AIP> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A804HKL7> , <https://identifiers.org/uniprot/O00170> , <https://identifiers.org/uniprot/A0A804HJ38> , <https://identifiers.org/uniprot/A0A804HIX8> , <https://identifiers.org/uniprot/A0A804HKH9> , <https://identifiers.org/uniprot/A0A804HKP8> , <https://identifiers.org/uniprot/E9PMH2> , <https://identifiers.org/uniprot/A0A804HKK3> , <https://identifiers.org/uniprot/V9GYQ3> , <https://identifiers.org/uniprot/A0A804HJ46> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18033785> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2586_r142469/DataNode/f39b7> , <http://rdf.wikipathways.org/Pathway/WP2586_r142469/DataNode/bee4e> , <http://rdf.wikipathways.org/Pathway/WP2586_r142469/DataNode/dacc1> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/E9PMH2> , <http://purl.uniprot.org/uniprot/A0A804HKK3> , <http://purl.uniprot.org/uniprot/O00170> , <http://purl.uniprot.org/uniprot/A0A804HKP8> , <http://purl.uniprot.org/uniprot/A0A804HIX8> , <http://purl.uniprot.org/uniprot/A0A804HJ38> , <http://purl.uniprot.org/uniprot/A0A804HKH9> , <http://purl.uniprot.org/uniprot/A0A804HKL7> , <http://purl.uniprot.org/uniprot/A0A804HJ46> , <http://purl.uniprot.org/uniprot/V9GYQ3> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000110711> .

<https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=svg&pwTitle=Pathway:WP2586&oldid=142469>
        rdf:type        foaf:Image ;
        dcterms:format  "image/svg+xml" .

<http://rdf.wikipathways.org/Pathway/WP2586_r142469/WP/Interaction/id40d6bab3>
        rdf:type          wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2586_r142469> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2586_r142469/Interaction/id40d6bab3> ;
        wp:participants   <https://identifiers.org/ncbigene/2099> .

<https://identifiers.org/ncbigene/27306>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "HPGDS" ;
        dc:identifier       <https://identifiers.org/ncbigene/27306> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "27306" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2586_r142469/Complex/cf474> , <https://identifiers.org/wikipathways/WP2586_r142469> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000163106> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/27306> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/HPGDS> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A384P5J0> , <https://identifiers.org/uniprot/O60760> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2586_r142469/DataNode/d11a8> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/O60760> , <http://purl.uniprot.org/uniprot/A0A384P5J0> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/27306> .

<https://identifiers.org/pubmed/19474220>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "19474220" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2586_r142469/Complex/cf474> , <https://identifiers.org/chebi/CHEBI:28119> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/19474220> .

obo:NCBITaxon_9606  obo:NCIT_C179773  "9606" .

<https://identifiers.org/ncbigene/3320>
        rdf:type            wp:DataNode , wp:GeneProduct , wp:Protein ;
        rdfs:label          "HSP90AA1" ;
        dc:identifier       <https://identifiers.org/ncbigene/3320> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "3320" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2586_r142469> , <http://rdf.wikipathways.org/Pathway/WP2586_r142469/Complex/e3e14> , <http://rdf.wikipathways.org/Pathway/WP2586_r142469/Complex/cf6c8> , <http://rdf.wikipathways.org/Pathway/WP2586_r142469/Complex/c3bdd> ;
        dcterms:references  <https://identifiers.org/pubmed/21856752> , <https://identifiers.org/pubmed/2843537> , <https://identifiers.org/pubmed/15322122> , <https://identifiers.org/pubmed/19158084> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000080824> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/3320> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/HSP90AA1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/G3V592> , <https://identifiers.org/uniprot/G3V2J8> , <https://identifiers.org/uniprot/K9JA46> , <https://identifiers.org/uniprot/H0YJF5> , <https://identifiers.org/uniprot/A0A0U1RR69> , <https://identifiers.org/uniprot/P07900> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2586_r142469/DataNode/f39f6> , <http://rdf.wikipathways.org/Pathway/WP2586_r142469/DataNode/aba94> , <http://rdf.wikipathways.org/Pathway/WP2586_r142469/DataNode/dad6b> , <http://rdf.wikipathways.org/Pathway/WP2586_r142469/DataNode/ec4c1> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/G3V2J8> , <http://purl.uniprot.org/uniprot/A0A0U1RR69> , <http://purl.uniprot.org/uniprot/H0YJF5> , <http://purl.uniprot.org/uniprot/G3V592> , <http://purl.uniprot.org/uniprot/P07900> , <http://purl.uniprot.org/uniprot/K9JA46> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/3320> .

<https://identifiers.org/pubmed/23512538>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "23512538" ;
        dcterms:isPartOf    <https://identifiers.org/ncbigene/1316> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/23512538> .

<http://rdf.wikipathways.org/Pathway/WP2586_r142469/WP/Interaction/faf4e>
        rdf:type            wp:Inhibition , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2586_r142469> ;
        dcterms:references  <https://identifiers.org/pubmed/9488039> , <https://identifiers.org/pubmed/10074425> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2586_r142469/Interaction/faf4e> ;
        wp:participants     <https://identifiers.org/ncbigene/1027> , <https://identifiers.org/ncbigene/1017> ;
        wp:source           <https://identifiers.org/ncbigene/1027> ;
        wp:target           <https://identifiers.org/ncbigene/1017> .

<https://identifiers.org/pubmed/14597617>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "14597617" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2586_r142469/WP/Interaction/id72845f06> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/14597617> .

<https://identifiers.org/wikipathways/WP697>
        rdf:type            wp:DataNode , wp:Pathway ;
        rdfs:label          "Estrogen metabolism" ;
        dc:identifier       <https://identifiers.org/wikipathways/WP697> ;
        dc:source           "WikiPathways" ;
        dcterms:identifier  "WP697" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2586_r142469> , <http://rdf.wikipathways.org/Pathway/WP2586_r142469/WP/Interaction/a5d40> , <http://rdf.wikipathways.org/Pathway/WP2586_r142469/WP/Interaction/fa583> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2586_r142469/DataNode/fed0f> ;
        foaf:page           <https://www.wikipathways.org/instance/WP697> .

<https://identifiers.org/pmc/PMC10711121>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed Central" ;
        dcterms:identifier  "PMC10711121" ;
        cito:cites          <https://identifiers.org/wikipathways/WP2586> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/PMC10711121> .

<https://identifiers.org/pubmed/19158084>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "19158084" ;
        dcterms:isPartOf    <https://identifiers.org/ncbigene/3320> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/19158084> .

<https://identifiers.org/pubmed/10961990>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "10961990" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2586_r142469/Complex/e3e14> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/10961990> .

<http://rdf.wikipathways.org/Pathway/WP2586_r142469/WP/Interaction/id4018eca7>
        rdf:type          wp:Binding , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2586_r142469> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2586_r142469/Interaction/id4018eca7> ;
        wp:participants   <https://identifiers.org/ncbigene/196> , <https://identifiers.org/chebi/CHEBI:28119> ;
        wp:source         <https://identifiers.org/chebi/CHEBI:28119> ;
        wp:target         <https://identifiers.org/ncbigene/196> .

<https://identifiers.org/ncbigene/17494212>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "EBNA-3" ;
        dc:identifier       <https://identifiers.org/ncbigene/17494212> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "17494212" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2586_r142469/WP/Interaction/idb5568ae7> , <https://identifiers.org/wikipathways/WP2586_r142469> ;
        dcterms:references  <https://identifiers.org/pubmed/10777214> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/17494212> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2586_r142469/DataNode/e1169> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/17494212> .

<http://rdf.wikipathways.org/Pathway/WP2586_r142469/WP/Interaction/idded8d7ad>
        rdf:type          wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2586_r142469> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2586_r142469/Interaction/idded8d7ad> .

<https://identifiers.org/ncbigene/7124>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "TNF" ;
        dc:identifier       <https://identifiers.org/ncbigene/7124> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "7124" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2586_r142469/WP/Interaction/c9443> , <https://identifiers.org/wikipathways/WP2586_r142469> , <http://rdf.wikipathways.org/Pathway/WP2586_r142469/WP/Interaction/f695c> ;
        dcterms:references  <https://identifiers.org/pubmed/17934341> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000232810> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/7124> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/TNF> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q5STB3> , <https://identifiers.org/uniprot/P01375> , <https://identifiers.org/uniprot/A0A8V8TNL2> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2586_r142469/DataNode/e7e7a> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P01375> , <http://purl.uniprot.org/uniprot/Q5STB3> , <http://purl.uniprot.org/uniprot/A0A8V8TNL2> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/7124> .

<http://rdf.wikipathways.org/Pathway/WP2586_r142469/WP/Interaction/id731096a5>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2586_r142469> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2586_r142469/Interaction/id731096a5> ;
        wp:participants   <https://identifiers.org/ncbigene/2099> , <https://identifiers.org/ensembl/ENSG00000110711> ;
        wp:source         <https://identifiers.org/ensembl/ENSG00000110711> ;
        wp:target         <https://identifiers.org/ncbigene/2099> .

<https://identifiers.org/ncbigene/4763>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "NF1" ;
        dc:identifier       <https://identifiers.org/ncbigene/4763> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "4763" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2586_r142469/Complex/a8219> , <https://identifiers.org/wikipathways/WP2586_r142469> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000196712> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/4763> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/NF1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A8I5KSM3> , <https://identifiers.org/uniprot/A0A8I5KYK6> , <https://identifiers.org/uniprot/K7EID4> , <https://identifiers.org/uniprot/J3QSG6> , <https://identifiers.org/uniprot/A0A8I5KV71> , <https://identifiers.org/uniprot/A0A8I5KWR6> , <https://identifiers.org/uniprot/K7ENT2> , <https://identifiers.org/uniprot/H0Y465> , <https://identifiers.org/uniprot/A0A8Q3WL49> , <https://identifiers.org/uniprot/A0A8I5KSC3> , <https://identifiers.org/uniprot/A0A8Q3WL11> , <https://identifiers.org/uniprot/J3KRT8> , <https://identifiers.org/uniprot/J3KSX8> , <https://identifiers.org/uniprot/J3KSB5> , <https://identifiers.org/uniprot/A0A1W2PS74> , <https://identifiers.org/uniprot/J3QQN8> , <https://identifiers.org/uniprot/P21359> , <https://identifiers.org/uniprot/A0A1W2PPA7> , <https://identifiers.org/uniprot/K7EJE7> , <https://identifiers.org/uniprot/A0A8Q3WL04> , <https://identifiers.org/uniprot/A0A8I5KWT7> , <https://identifiers.org/uniprot/J3QLS2> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2586_r142469/DataNode/ffa48> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A1W2PS74> , <http://purl.uniprot.org/uniprot/J3KRT8> , <http://purl.uniprot.org/uniprot/A0A8Q3WL49> , <http://purl.uniprot.org/uniprot/A0A8I5KYK6> , <http://purl.uniprot.org/uniprot/P21359> , <http://purl.uniprot.org/uniprot/K7ENT2> , <http://purl.uniprot.org/uniprot/H0Y465> , <http://purl.uniprot.org/uniprot/A0A8I5KSM3> , <http://purl.uniprot.org/uniprot/A0A8I5KSC3> , <http://purl.uniprot.org/uniprot/A0A8I5KV71> , <http://purl.uniprot.org/uniprot/J3QSG6> , <http://purl.uniprot.org/uniprot/A0A1W2PPA7> , <http://purl.uniprot.org/uniprot/A0A8Q3WL04> , <http://purl.uniprot.org/uniprot/J3KSB5> , <http://purl.uniprot.org/uniprot/J3QQN8> , <http://purl.uniprot.org/uniprot/A0A8Q3WL11> , <http://purl.uniprot.org/uniprot/K7EID4> , <http://purl.uniprot.org/uniprot/K7EJE7> , <http://purl.uniprot.org/uniprot/A0A8I5KWT7> , <http://purl.uniprot.org/uniprot/J3KSX8> , <http://purl.uniprot.org/uniprot/J3QLS2> , <http://purl.uniprot.org/uniprot/A0A8I5KWR6> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/4763> .

<https://identifiers.org/pmc/PMC7779061>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed Central" ;
        dcterms:identifier  "PMC7779061" ;
        cito:cites          <https://identifiers.org/wikipathways/WP2586> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/PMC7779061> .

<http://rdf.wikipathways.org/Pathway/WP2586_r142469/WP/Interaction/b6820>
        rdf:type          wp:Inhibition , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2586_r142469> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2586_r142469/Interaction/b6820> ;
        wp:participants   <https://identifiers.org/ncbigene/1869> , <https://identifiers.org/ncbigene/5925> ;
        wp:source         <https://identifiers.org/ncbigene/5925> ;
        wp:target         <https://identifiers.org/ncbigene/1869> .

<http://rdf.wikipathways.org/Pathway/WP2586_r142469/WP/Interaction/f695c>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2586_r142469> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2586_r142469/Interaction/f695c> ;
        wp:participants   <https://identifiers.org/ncbigene/7124> , <https://identifiers.org/wikipathways/WP1910> ;
        wp:source         <https://identifiers.org/wikipathways/WP1910> ;
        wp:target         <https://identifiers.org/ncbigene/7124> .

<https://identifiers.org/wikipathways/WP408>
        rdf:type            wp:Pathway , wp:DataNode ;
        rdfs:label          "Oxidative stress" ;
        dc:identifier       <https://identifiers.org/wikipathways/WP408> ;
        dc:source           "WikiPathways" ;
        dcterms:identifier  "WP408" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2586_r142469> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2586_r142469/DataNode/c854d> ;
        foaf:page           <https://www.wikipathways.org/instance/WP408> .

<https://identifiers.org/ncbigene/5743>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "PTGS2" ;
        dc:identifier       <https://identifiers.org/ncbigene/5743> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "5743" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2586_r142469/WP/Interaction/idc77daae1> , <https://identifiers.org/wikipathways/WP2586_r142469> ;
        dcterms:references  <https://identifiers.org/pubmed/19203995> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000073756> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/5743> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/PTGS2> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/P35354> , <https://identifiers.org/uniprot/Q6ZYK7> , <https://identifiers.org/uniprot/A0A7P0T828> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2586_r142469/DataNode/ca04f> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A7P0T828> , <http://purl.uniprot.org/uniprot/Q6ZYK7> , <http://purl.uniprot.org/uniprot/P35354> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/5743> .

<https://identifiers.org/ncbigene/84722>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "PSRC1" ;
        dc:identifier       <https://identifiers.org/ncbigene/84722> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "84722" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2586_r142469> , <http://rdf.wikipathways.org/Pathway/WP2586_r142469/Complex/bca0b> , <http://rdf.wikipathways.org/Pathway/WP2586_r142469/Complex/df20e> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000134222> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/84722> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/PSRC1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q5T2Z0> , <https://identifiers.org/uniprot/Q5T2Z1> , <https://identifiers.org/uniprot/S4R3S8> , <https://identifiers.org/uniprot/Q6PGN9> , <https://identifiers.org/uniprot/A0A024R099> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2586_r142469/DataNode/dac5e> , <http://rdf.wikipathways.org/Pathway/WP2586_r142469/DataNode/f1d0b> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q5T2Z1> , <http://purl.uniprot.org/uniprot/Q6PGN9> , <http://purl.uniprot.org/uniprot/A0A024R099> , <http://purl.uniprot.org/uniprot/S4R3S8> , <http://purl.uniprot.org/uniprot/Q5T2Z0> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/84722> .

<https://identifiers.org/ncbigene/8204>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "NRIP1" ;
        dc:identifier       <https://identifiers.org/ncbigene/8204> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "8204" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2586_r142469/Complex/a8219> , <http://rdf.wikipathways.org/Pathway/WP2586_r142469/WP/Interaction/id421faf29> , <https://identifiers.org/wikipathways/WP2586_r142469> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000180530> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/8204> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/NRIP1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A1B0GUG9> , <https://identifiers.org/uniprot/C9J130> , <https://identifiers.org/uniprot/P48552> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2586_r142469/DataNode/d8ae0> , <http://rdf.wikipathways.org/Pathway/WP2586_r142469/DataNode/da145> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/C9J130> , <http://purl.uniprot.org/uniprot/A0A1B0GUG9> , <http://purl.uniprot.org/uniprot/P48552> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/8204> .

<http://rdf.wikipathways.org/Pathway/WP2586_r142469/WP/Interaction/fa583>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2586_r142469> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2586_r142469/Interaction/fa583> ;
        wp:participants   <https://identifiers.org/wikipathways/WP697> , <https://identifiers.org/ncbigene/1545> ;
        wp:source         <https://identifiers.org/ncbigene/1545> ;
        wp:target         <https://identifiers.org/wikipathways/WP697> .

<http://rdf.wikipathways.org/Pathway/WP2586_r142469/WP/Interaction/idcfc279cb>
        rdf:type          wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2586_r142469> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2586_r142469/Interaction/idcfc279cb> .

<https://identifiers.org/ncbigene/1316>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "KLF6" ;
        dc:identifier       <https://identifiers.org/ncbigene/1316> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "1316" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2586_r142469> ;
        dcterms:references  <https://identifiers.org/pubmed/23512538> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000067082> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/1316> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/KLF6> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q99612> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2586_r142469/DataNode/a59c1> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q99612> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/1316> .

<https://identifiers.org/wikidata/Q15322916>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "Calcium channel" ;
        dc:identifier       <https://identifiers.org/wikidata/Q15322916> ;
        dc:source           "Wikidata" ;
        dcterms:identifier  "Q15322916" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2586_r142469> ;
        dcterms:references  <https://identifiers.org/pubmed/18089838> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q15322916> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2586_r142469/DataNode/c47aa> ;
        foaf:page           <https://scholia.toolforge.org/Q15322916> .

<https://identifiers.org/pubmed/21856752>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "21856752" ;
        dcterms:isPartOf    <https://identifiers.org/ncbigene/3320> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/21856752> .

<http://rdf.wikipathways.org/Pathway/WP2586_r142469/Complex/e3e14>
        rdf:type                       wp:Complex , wp:DataNode ;
        dcterms:bibliographicCitation  <https://identifiers.org/pubmed/10961990> ;
        dcterms:isPartOf               <https://identifiers.org/wikipathways/WP2586_r142469> ;
        dcterms:references             <https://identifiers.org/pubmed/10961990> ;
        wp:isAbout                     <http://rdf.wikipathways.org/Pathway/WP2586_r142469/Group/e3e14> ;
        wp:participants                <https://identifiers.org/ensembl/ENSG00000110711> , <https://identifiers.org/ncbigene/3320> , <https://identifiers.org/ncbigene/196> .

<https://identifiers.org/pubmed/8910454>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "8910454" ;
        dcterms:isPartOf    <https://identifiers.org/ncbigene/1545> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/8910454> .

<http://rdf.wikipathways.org/Pathway/WP2586_r142469/WP/Interaction/de447>
        rdf:type          wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2586_r142469> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2586_r142469/Interaction/de447> .

<https://identifiers.org/wikipathways/WP2586>
        pav:hasVersion  <https://identifiers.org/wikipathways/WP2586_r142469> .

<https://identifiers.org/ncbigene/5325>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "ZAC1" ;
        dc:identifier       <https://identifiers.org/ncbigene/5325> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "5325" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2586_r142469> , <http://rdf.wikipathways.org/Pathway/WP2586_r142469/WP/Interaction/idff773eff> ;
        dcterms:references  <https://identifiers.org/pubmed/22659247> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000118495> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/5325> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/PLAGL1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A0D9SFM8> , <https://identifiers.org/uniprot/A1YLA2> , <https://identifiers.org/uniprot/A0A0D9SFI7> , <https://identifiers.org/uniprot/A1YLA1> , <https://identifiers.org/uniprot/A0A3B3IRN7> , <https://identifiers.org/uniprot/A0A0D9SEQ4> , <https://identifiers.org/uniprot/A0A0D9SGF7> , <https://identifiers.org/uniprot/Q9UM63> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2586_r142469/DataNode/e95c9> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q9UM63> , <http://purl.uniprot.org/uniprot/A1YLA1> , <http://purl.uniprot.org/uniprot/A0A3B3IRN7> , <http://purl.uniprot.org/uniprot/A0A0D9SFI7> , <http://purl.uniprot.org/uniprot/A1YLA2> , <http://purl.uniprot.org/uniprot/A0A0D9SEQ4> , <http://purl.uniprot.org/uniprot/A0A0D9SFM8> , <http://purl.uniprot.org/uniprot/A0A0D9SGF7> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/5325> .

<https://identifiers.org/ncbigene/948>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "CD36" ;
        dc:identifier       <https://identifiers.org/ncbigene/948> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "948" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2586_r142469> , <http://rdf.wikipathways.org/Pathway/WP2586_r142469/Complex/b4164> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000135218> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/948> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/CD36> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/E7EX47> , <https://identifiers.org/uniprot/E7EWI4> , <https://identifiers.org/uniprot/E9PC45> , <https://identifiers.org/uniprot/E7EU05> , <https://identifiers.org/uniprot/E7ERZ9> , <https://identifiers.org/uniprot/E7EVU1> , <https://identifiers.org/uniprot/H0YEE7> , <https://identifiers.org/uniprot/A4D1B1> , <https://identifiers.org/uniprot/E9PLT1> , <https://identifiers.org/uniprot/P16671> , <https://identifiers.org/uniprot/E9PJX8> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2586_r142469/DataNode/cb96c> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/H0YEE7> , <http://purl.uniprot.org/uniprot/E9PC45> , <http://purl.uniprot.org/uniprot/E7ERZ9> , <http://purl.uniprot.org/uniprot/E7EX47> , <http://purl.uniprot.org/uniprot/A4D1B1> , <http://purl.uniprot.org/uniprot/E9PLT1> , <http://purl.uniprot.org/uniprot/E7EVU1> , <http://purl.uniprot.org/uniprot/E7EWI4> , <http://purl.uniprot.org/uniprot/E9PJX8> , <http://purl.uniprot.org/uniprot/E7EU05> , <http://purl.uniprot.org/uniprot/P16671> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/948> .

<https://identifiers.org/pubmed/10620335>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "10620335" ;
        dcterms:isPartOf    <https://identifiers.org/ncbigene/2099> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/10620335> .

<https://identifiers.org/ncbigene/2033>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "EP300" ;
        dc:identifier       <https://identifiers.org/ncbigene/2033> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "2033" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2586_r142469/Complex/bca0b> , <https://identifiers.org/wikipathways/WP2586_r142469> , <http://rdf.wikipathways.org/Pathway/WP2586_r142469/Complex/a8219> , <http://rdf.wikipathways.org/Pathway/WP2586_r142469/Complex/df20e> ;
        dcterms:references  <https://identifiers.org/pubmed/19255421> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000100393> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/2033> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/EP300> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A994J6T4> , <https://identifiers.org/uniprot/A0A994J3N7> , <https://identifiers.org/uniprot/A0A669KB12> , <https://identifiers.org/uniprot/A0A0U1RR87> , <https://identifiers.org/uniprot/Q09472> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2586_r142469/DataNode/f2dca> , <http://rdf.wikipathways.org/Pathway/WP2586_r142469/DataNode/b68c6> , <http://rdf.wikipathways.org/Pathway/WP2586_r142469/DataNode/cc9aa> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q09472> , <http://purl.uniprot.org/uniprot/A0A0U1RR87> , <http://purl.uniprot.org/uniprot/A0A994J3N7> , <http://purl.uniprot.org/uniprot/A0A669KB12> , <http://purl.uniprot.org/uniprot/A0A994J6T4> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/2033> .

<https://identifiers.org/pubmed/19255421>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "19255421" ;
        dcterms:isPartOf    <https://identifiers.org/ncbigene/2033> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/19255421> .

<https://identifiers.org/pubmed/18336843>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "18336843" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2586_r142469/WP/Interaction/c9443> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/18336843> .

<https://identifiers.org/ncbigene/1545>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "CYP1B1" ;
        dc:identifier       <https://identifiers.org/ncbigene/1545> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "1545" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2586_r142469/WP/Interaction/f1509> , <http://rdf.wikipathways.org/Pathway/WP2586_r142469/WP/Interaction/a897d> , <http://rdf.wikipathways.org/Pathway/WP2586_r142469/WP/Interaction/c9443> , <https://identifiers.org/wikipathways/WP2586_r142469> , <http://rdf.wikipathways.org/Pathway/WP2586_r142469/WP/Interaction/fa583> ;
        dcterms:references  <https://identifiers.org/pubmed/11502724> , <https://identifiers.org/pubmed/8910454> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000138061> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/1545> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/CYP1B1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A087WW26> , <https://identifiers.org/uniprot/Q16678> , <https://identifiers.org/uniprot/A0A087WUQ7> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2586_r142469/DataNode/c2cc5> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q16678> , <http://purl.uniprot.org/uniprot/A0A087WW26> , <http://purl.uniprot.org/uniprot/A0A087WUQ7> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/1545> .

<https://identifiers.org/pubmed/9504046>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "9504046" ;
        dcterms:isPartOf    <https://identifiers.org/ncbigene/1956> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/9504046> .

<https://identifiers.org/pubmed/3266253>
        rdf:type            wp:PublicationReference ;
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        dcterms:isPartOf    <https://identifiers.org/ncbigene/1956> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/3266253> .

<https://identifiers.org/pubmed/11502724>
        rdf:type            wp:PublicationReference ;
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        dcterms:isPartOf    <https://identifiers.org/ncbigene/1545> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/11502724> .

<http://rdf.wikipathways.org/Pathway/WP2586_r142469/WP/Interaction/id9f884584>
        rdf:type          wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2586_r142469> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2586_r142469/Interaction/id9f884584> ;
        wp:participants   <https://identifiers.org/ncbigene/1026> .

<https://identifiers.org/ncbigene/1027>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "CDKN1B" ;
        dc:identifier       <https://identifiers.org/ncbigene/1027> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "1027" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2586_r142469/WP/Interaction/id741ef049> , <http://rdf.wikipathways.org/Pathway/WP2586_r142469/WP/Interaction/faf4e> , <https://identifiers.org/wikipathways/WP2586_r142469> ;
        dcterms:references  <https://identifiers.org/pubmed/10398686> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000111276> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/1027> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/CDKN1B> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q6I9V6> , <https://identifiers.org/uniprot/E7ES52> , <https://identifiers.org/uniprot/H7C2T1> , <https://identifiers.org/uniprot/P46527> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2586_r142469/DataNode/ab320> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/E7ES52> , <http://purl.uniprot.org/uniprot/P46527> , <http://purl.uniprot.org/uniprot/H7C2T1> , <http://purl.uniprot.org/uniprot/Q6I9V6> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/1027> .

<https://identifiers.org/pubmed/12223212>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "12223212" ;
        dcterms:isPartOf    <https://identifiers.org/chebi/CHEBI:33848> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/12223212> .

<http://rdf.wikipathways.org/Pathway/WP2586_r142469/WP/Interaction/id72845f06>
        rdf:type            wp:DirectedInteraction , wp:Interaction , wp:Inhibition ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2586_r142469> ;
        dcterms:references  <https://identifiers.org/pubmed/14597617> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2586_r142469/Interaction/id72845f06> ;
        wp:participants     <https://identifiers.org/ncbigene/1017> , <https://identifiers.org/ncbigene/1026> ;
        wp:source           <https://identifiers.org/ncbigene/1026> ;
        wp:target           <https://identifiers.org/ncbigene/1017> .

<https://identifiers.org/pubmed/9380030>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "9380030" ;
        dcterms:isPartOf    <https://identifiers.org/ncbigene/6714> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/9380030> .

<https://identifiers.org/pubmed/8396713>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "8396713" ;
        dcterms:isPartOf    <https://identifiers.org/ncbigene/405> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/8396713> .

<https://identifiers.org/pmc/PMC8868589>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed Central" ;
        dcterms:identifier  "PMC8868589" ;
        cito:cites          <https://identifiers.org/wikipathways/WP2586> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/PMC8868589> .

<http://rdf.wikipathways.org/Pathway/WP2586_r142469/WP/Interaction/a5d40>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2586_r142469> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2586_r142469/Interaction/a5d40> ;
        wp:participants   <https://identifiers.org/wikipathways/WP697> , <https://identifiers.org/ncbigene/1544> ;
        wp:source         <https://identifiers.org/ncbigene/1544> ;
        wp:target         <https://identifiers.org/wikipathways/WP697> .

<https://identifiers.org/ncbigene/196>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "AHR" ;
        dc:identifier       <https://identifiers.org/ncbigene/196> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "196" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2586_r142469/Complex/e3e14> , <http://rdf.wikipathways.org/Pathway/WP2586_r142469/WP/Interaction/idbc089a2a> , <http://rdf.wikipathways.org/Pathway/WP2586_r142469/WP/Interaction/id4018eca7> , <https://identifiers.org/wikipathways/WP2586_r142469> , <http://rdf.wikipathways.org/Pathway/WP2586_r142469/Complex/cf6c8> ;
        dcterms:references  <https://identifiers.org/pubmed/22903824> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000106546> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/196> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/AHR> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A2R8Y7G1> , <https://identifiers.org/uniprot/P35869> , <https://identifiers.org/uniprot/A0A024R9Z8> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2586_r142469/DataNode/ece46> , <http://rdf.wikipathways.org/Pathway/WP2586_r142469/DataNode/bb43a> , <http://rdf.wikipathways.org/Pathway/WP2586_r142469/DataNode/a8e72> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A2R8Y7G1> , <http://purl.uniprot.org/uniprot/A0A024R9Z8> , <http://purl.uniprot.org/uniprot/P35869> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/196> .

<https://identifiers.org/ncbigene/57491>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "AHRR" ;
        dc:identifier       <https://identifiers.org/ncbigene/57491> ;
        dc:source           "Entrez Gene" ;
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        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2586_r142469> , <http://rdf.wikipathways.org/Pathway/WP2586_r142469/WP/Interaction/idac09c4e3> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000063438> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/57491> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/AHRR> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/E5RHE0> , <https://identifiers.org/uniprot/A0A494BZY4> , <https://identifiers.org/uniprot/E5RFG4> , <https://identifiers.org/uniprot/D6RE68> , <https://identifiers.org/uniprot/A0A7I2PK40> , <https://identifiers.org/uniprot/G3V143> , <https://identifiers.org/uniprot/H0YA43> , <https://identifiers.org/uniprot/E5RGQ2> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2586_r142469/DataNode/a3f83> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/H0YA43> , <http://purl.uniprot.org/uniprot/D6RE68> , <http://purl.uniprot.org/uniprot/E5RGQ2> , <http://purl.uniprot.org/uniprot/E5RHE0> , <http://purl.uniprot.org/uniprot/E5RFG4> , <http://purl.uniprot.org/uniprot/A0A7I2PK40> , <http://purl.uniprot.org/uniprot/A0A494BZY4> , <http://purl.uniprot.org/uniprot/G3V143> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/57491> .

<http://rdf.wikipathways.org/Pathway/WP2586_r142469/WP/Interaction/id8cff4ef7>
        rdf:type          wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2586_r142469> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2586_r142469/Interaction/id8cff4ef7> ;
        wp:participants   <https://identifiers.org/ncbigene/1544> , <https://identifiers.org/ncbigene/1543> .

<http://rdf.wikipathways.org/Pathway/WP2586_r142469/WP/Interaction/idbd129eca>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2586_r142469> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2586_r142469/Interaction/idbd129eca> ;
        wp:participants   <https://identifiers.org/wikipathways/WP1539> , <https://identifiers.org/ncbigene/7422> ;
        wp:source         <https://identifiers.org/ncbigene/7422> ;
        wp:target         <https://identifiers.org/wikipathways/WP1539> .

<https://identifiers.org/ncbigene/5925>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "RB1" ;
        dc:identifier       <https://identifiers.org/ncbigene/5925> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "5925" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2586_r142469/WP/Interaction/b6820> , <http://rdf.wikipathways.org/Pathway/WP2586_r142469/WP/Interaction/idc40b6454> , <https://identifiers.org/wikipathways/WP2586_r142469> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000139687> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/5925> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/RB1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/P06400> , <https://identifiers.org/uniprot/A0A2R8YFL6> , <https://identifiers.org/uniprot/A0A2R8Y743> , <https://identifiers.org/uniprot/A0A024RDV3> , <https://identifiers.org/uniprot/Q92728> , <https://identifiers.org/uniprot/A0A3B3IS71> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2586_r142469/DataNode/b8267> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A3B3IS71> , <http://purl.uniprot.org/uniprot/P06400> , <http://purl.uniprot.org/uniprot/Q92728> , <http://purl.uniprot.org/uniprot/A0A2R8Y743> , <http://purl.uniprot.org/uniprot/A0A2R8YFL6> , <http://purl.uniprot.org/uniprot/A0A024RDV3> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/5925> .

<https://identifiers.org/pubmed/19617630>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "19617630" ;
        dcterms:isPartOf    <https://identifiers.org/ncbigene/7422> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/19617630> .

<https://identifiers.org/ncbigene/2099>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "ESR1" ;
        dc:identifier       <https://identifiers.org/ncbigene/2099> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "2099" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2586_r142469/WP/Interaction/id40d6bab3> , <http://rdf.wikipathways.org/Pathway/WP2586_r142469/WP/Interaction/id731096a5> , <https://identifiers.org/wikipathways/WP2586_r142469> ;
        dcterms:references  <https://identifiers.org/pubmed/19574409> , <https://identifiers.org/pubmed/10620335> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000091831> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/2099> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/ESR1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q9H2M1> , <https://identifiers.org/uniprot/B0QYW7> , <https://identifiers.org/uniprot/P03372> , <https://identifiers.org/uniprot/H0Y4W6> , <https://identifiers.org/uniprot/Q9H2M2> , <https://identifiers.org/uniprot/G4XH65> , <https://identifiers.org/uniprot/Q9UE35> , <https://identifiers.org/uniprot/Q5T5H8> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2586_r142469/DataNode/acbf4> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q9UE35> , <http://purl.uniprot.org/uniprot/Q9H2M2> , <http://purl.uniprot.org/uniprot/B0QYW7> , <http://purl.uniprot.org/uniprot/P03372> , <http://purl.uniprot.org/uniprot/H0Y4W6> , <http://purl.uniprot.org/uniprot/Q9H2M1> , <http://purl.uniprot.org/uniprot/G4XH65> , <http://purl.uniprot.org/uniprot/Q5T5H8> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/2099> .

<https://identifiers.org/pubmed/22659247>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "22659247" ;
        dcterms:isPartOf    <https://identifiers.org/ncbigene/5325> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/22659247> .

<https://identifiers.org/pubmed/19203995>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "19203995" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2586_r142469/WP/Interaction/idc77daae1> , <https://identifiers.org/ncbigene/5743> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/19203995> .

<https://identifiers.org/chebi/CHEBI:33848>
        rdf:type            wp:Metabolite , wp:DataNode ;
        rdfs:label          "PAH" ;
        dc:identifier       <https://identifiers.org/chebi/CHEBI:33848> ;
        dc:source           "ChEBI" ;
        dcterms:identifier  "CHEBI:33848" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2586_r142469> , <http://rdf.wikipathways.org/Pathway/WP2586_r142469/WP/Interaction/idbc089a2a> ;
        dcterms:references  <https://identifiers.org/pubmed/12223212> , <https://identifiers.org/pubmed/11097088> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:33848> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q407212> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2586_r142469/DataNode/d3a00> , <http://rdf.wikipathways.org/Pathway/WP2586_r142469/DataNode/d9b90> ;
        foaf:page           <https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:33848> .

<https://identifiers.org/ncbigene/9612>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "NCOR2" ;
        dc:identifier       <https://identifiers.org/ncbigene/9612> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "9612" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2586_r142469/Complex/a8219> , <https://identifiers.org/wikipathways/WP2586_r142469> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000196498> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/9612> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/NCOR2> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/C9JNV9> , <https://identifiers.org/uniprot/C9J330> , <https://identifiers.org/uniprot/H7C1J7> , <https://identifiers.org/uniprot/H7C0P3> , <https://identifiers.org/uniprot/Q9Y618> , <https://identifiers.org/uniprot/H7BZU2> , <https://identifiers.org/uniprot/H0YGK8> , <https://identifiers.org/uniprot/H7C184> , <https://identifiers.org/uniprot/H7C1Y3> , <https://identifiers.org/uniprot/C9JE98> , <https://identifiers.org/uniprot/H7C2R5> , <https://identifiers.org/uniprot/C9J0Q5> , <https://identifiers.org/uniprot/C9JQE8> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2586_r142469/DataNode/d7eb6> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/C9JNV9> , <http://purl.uniprot.org/uniprot/Q9Y618> , <http://purl.uniprot.org/uniprot/H7BZU2> , <http://purl.uniprot.org/uniprot/C9JE98> , <http://purl.uniprot.org/uniprot/H7C1Y3> , <http://purl.uniprot.org/uniprot/H7C2R5> , <http://purl.uniprot.org/uniprot/C9J330> , <http://purl.uniprot.org/uniprot/C9J0Q5> , <http://purl.uniprot.org/uniprot/C9JQE8> , <http://purl.uniprot.org/uniprot/H0YGK8> , <http://purl.uniprot.org/uniprot/H7C184> , <http://purl.uniprot.org/uniprot/H7C0P3> , <http://purl.uniprot.org/uniprot/H7C1J7> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/9612> .

<https://identifiers.org/ncbigene/4790>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "NFKB1" ;
        dc:identifier       <https://identifiers.org/ncbigene/4790> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "4790" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2586_r142469/Complex/df20e> , <https://identifiers.org/wikipathways/WP2586_r142469> , <http://rdf.wikipathways.org/Pathway/WP2586_r142469/Complex/cdac9> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000109320> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/4790> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/NFKB1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/D6RH30> , <https://identifiers.org/uniprot/A0A8V8TLB2> , <https://identifiers.org/uniprot/D6RC45> , <https://identifiers.org/uniprot/P19838> , <https://identifiers.org/uniprot/A0A494C1E9> , <https://identifiers.org/uniprot/A0A494C157> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2586_r142469/DataNode/f369f> , <http://rdf.wikipathways.org/Pathway/WP2586_r142469/DataNode/e7f53> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/D6RH30> , <http://purl.uniprot.org/uniprot/P19838> , <http://purl.uniprot.org/uniprot/A0A8V8TLB2> , <http://purl.uniprot.org/uniprot/A0A494C157> , <http://purl.uniprot.org/uniprot/D6RC45> , <http://purl.uniprot.org/uniprot/A0A494C1E9> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/4790> .

<https://identifiers.org/ncbigene/7422>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "VEGFA" ;
        dc:identifier       <https://identifiers.org/ncbigene/7422> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "7422" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2586_r142469> , <http://rdf.wikipathways.org/Pathway/WP2586_r142469/WP/Interaction/idbd129eca> ;
        dcterms:references  <https://identifiers.org/pubmed/19617630> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000112715> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/7422> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/VEGFA> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A0A0MSI7> , <https://identifiers.org/uniprot/H3BLW8> , <https://identifiers.org/uniprot/P15692> , <https://identifiers.org/uniprot/H0YBI8> , <https://identifiers.org/uniprot/A0A0A0MR43> , <https://identifiers.org/uniprot/A0A0A0MSH5> , <https://identifiers.org/uniprot/J3KPA4> , <https://identifiers.org/uniprot/H0YBZ0> , <https://identifiers.org/uniprot/A0A0A0MTB2> , <https://identifiers.org/uniprot/A0A0Y0IMM4> , <https://identifiers.org/uniprot/A0A5F9ZH41> , <https://identifiers.org/uniprot/A0A0A0MSH7> , <https://identifiers.org/uniprot/A0A0A0MRQ4> , <https://identifiers.org/uniprot/A2A2V4> , <https://identifiers.org/uniprot/A0A024RD33> , <https://identifiers.org/uniprot/A0A024RD37> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2586_r142469/DataNode/a75a4> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A0Y0IMM4> , <http://purl.uniprot.org/uniprot/A0A0A0MSH5> , <http://purl.uniprot.org/uniprot/J3KPA4> , <http://purl.uniprot.org/uniprot/P15692> , <http://purl.uniprot.org/uniprot/A2A2V4> , <http://purl.uniprot.org/uniprot/A0A024RD37> , <http://purl.uniprot.org/uniprot/A0A0A0MSH7> , <http://purl.uniprot.org/uniprot/H0YBI8> , <http://purl.uniprot.org/uniprot/H0YBZ0> , <http://purl.uniprot.org/uniprot/A0A0A0MRQ4> , <http://purl.uniprot.org/uniprot/A0A0A0MR43> , <http://purl.uniprot.org/uniprot/A0A0A0MSI7> , <http://purl.uniprot.org/uniprot/A0A5F9ZH41> , <http://purl.uniprot.org/uniprot/A0A024RD33> , <http://purl.uniprot.org/uniprot/A0A0A0MTB2> , <http://purl.uniprot.org/uniprot/H3BLW8> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/7422> .

<http://rdf.wikipathways.org/Pathway/WP2586_r142469/WP/Interaction/id7bd0c467>
        rdf:type            wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2586_r142469> ;
        dcterms:references  <https://identifiers.org/pubmed/19366855> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2586_r142469/Interaction/id7bd0c467> ;
        wp:participants     <https://identifiers.org/ncbigene/5979> , <https://identifiers.org/ensembl/ENSG00000110711> ;
        wp:source           <https://identifiers.org/ensembl/ENSG00000110711> ;
        wp:target           <https://identifiers.org/ncbigene/5979> .

<https://identifiers.org/pubmed/16679317>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "16679317" ;
        dcterms:isPartOf    <https://identifiers.org/ncbigene/6346> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/16679317> .

<https://identifiers.org/pubmed/11259609>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "11259609" ;
        dcterms:isPartOf    <https://identifiers.org/uniprot/P06400> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/11259609> .

<https://identifiers.org/pubmed/17934341>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "17934341" ;
        dcterms:isPartOf    <https://identifiers.org/ncbigene/7124> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/17934341> .

<https://identifiers.org/pubmed/10395741>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "10395741" ;
        dcterms:isPartOf    <https://identifiers.org/ncbigene/135112> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/10395741> .

<https://identifiers.org/uniprot/P06400>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "pRb" ;
        dc:identifier       <https://identifiers.org/uniprot/P06400> ;
        dc:source           "UniProtKB" ;
        dcterms:identifier  "P06400" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2586_r142469/WP/Interaction/idf8007aad> , <https://identifiers.org/wikipathways/WP2586_r142469> ;
        dcterms:references  <https://identifiers.org/pubmed/9712901> , <https://identifiers.org/pubmed/11259609> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000139687> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/5925> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/RB1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/P06400> , <https://identifiers.org/uniprot/A0A024RDV3> , <https://identifiers.org/uniprot/A0A2R8Y743> , <https://identifiers.org/uniprot/A0A2R8YFL6> , <https://identifiers.org/uniprot/A0A3B3IS71> , <https://identifiers.org/uniprot/Q92728> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2586_r142469/DataNode/da5d7> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P06400> , <http://purl.uniprot.org/uniprot/A0A024RDV3> , <http://purl.uniprot.org/uniprot/A0A2R8YFL6> , <http://purl.uniprot.org/uniprot/Q92728> , <http://purl.uniprot.org/uniprot/A0A3B3IS71> , <http://purl.uniprot.org/uniprot/A0A2R8Y743> ;
        foaf:page           <http://www.uniprot.org/uniprot/P06400> .

<https://identifiers.org/pubmed/9488039>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "9488039" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2586_r142469/WP/Interaction/faf4e> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/9488039> .

<https://identifiers.org/ncbigene/1869>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "E2F1" ;
        dc:identifier       <https://identifiers.org/ncbigene/1869> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "1869" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2586_r142469> , <http://rdf.wikipathways.org/Pathway/WP2586_r142469/WP/Interaction/b6820> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000101412> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/1869> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/E2F1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q01094> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2586_r142469/DataNode/e1c52> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q01094> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/1869> .

<http://rdf.wikipathways.org/Pathway/WP2586_r142469/WP/Interaction/idbc089a2a>
        rdf:type          wp:Binding , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2586_r142469> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2586_r142469/Interaction/idbc089a2a> ;
        wp:participants   <https://identifiers.org/ncbigene/196> , <https://identifiers.org/chebi/CHEBI:33848> ;
        wp:source         <https://identifiers.org/chebi/CHEBI:33848> ;
        wp:target         <https://identifiers.org/ncbigene/196> .

<https://identifiers.org/ensembl/ENSG00000213281>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "NRAS" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000213281> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000213281" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2586_r142469> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000213281> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/4893> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/NRAS> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q5U091> , <https://identifiers.org/uniprot/P01111> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18030215> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2586_r142469/DataNode/bfbc2> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P01111> , <http://purl.uniprot.org/uniprot/Q5U091> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000213281> .

<http://rdf.wikipathways.org/Pathway/WP2586_r142469/WP/Interaction/idc77daae1>
        rdf:type            wp:Interaction , wp:DirectedInteraction , wp:TranscriptionTranslation ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2586_r142469> ;
        dcterms:references  <https://identifiers.org/pubmed/19203995> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2586_r142469/Interaction/idc77daae1> ;
        wp:participants     <https://identifiers.org/ncbigene/5743> , <https://identifiers.org/ncbigene/5594> ;
        wp:source           <https://identifiers.org/ncbigene/5594> ;
        wp:target           <https://identifiers.org/ncbigene/5743> .

<https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=png&pwTitle=Pathway:WP2586&oldid=142469>
        rdf:type        foaf:Image ;
        dcterms:format  "image/png" .

<https://identifiers.org/ncbigene/5970>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "RELA" ;
        dc:identifier       <https://identifiers.org/ncbigene/5970> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "5970" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2586_r142469> , <http://rdf.wikipathways.org/Pathway/WP2586_r142469/Complex/df20e> , <http://rdf.wikipathways.org/Pathway/WP2586_r142469/Complex/cdac9> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000173039> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/5970> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/RELA> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A087X0W8> , <https://identifiers.org/uniprot/E9PSE4> , <https://identifiers.org/uniprot/E9PQS6> , <https://identifiers.org/uniprot/E9PKH5> , <https://identifiers.org/uniprot/E9PMD5> , <https://identifiers.org/uniprot/H0YCB4> , <https://identifiers.org/uniprot/E9PI38> , <https://identifiers.org/uniprot/E9PKV4> , <https://identifiers.org/uniprot/Q2TAM5> , <https://identifiers.org/uniprot/E9PM47> , <https://identifiers.org/uniprot/Q04206> , <https://identifiers.org/uniprot/E9PJR1> , <https://identifiers.org/uniprot/E9PNV4> , <https://identifiers.org/uniprot/E9PNK5> , <https://identifiers.org/uniprot/E9PRX2> , <https://identifiers.org/uniprot/E9PJZ9> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2586_r142469/DataNode/aaceb> , <http://rdf.wikipathways.org/Pathway/WP2586_r142469/DataNode/b2d82> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/E9PJZ9> , <http://purl.uniprot.org/uniprot/E9PJR1> , <http://purl.uniprot.org/uniprot/E9PKH5> , <http://purl.uniprot.org/uniprot/H0YCB4> , <http://purl.uniprot.org/uniprot/E9PNK5> , <http://purl.uniprot.org/uniprot/Q04206> , <http://purl.uniprot.org/uniprot/E9PMD5> , <http://purl.uniprot.org/uniprot/E9PM47> , <http://purl.uniprot.org/uniprot/E9PSE4> , <http://purl.uniprot.org/uniprot/A0A087X0W8> , <http://purl.uniprot.org/uniprot/Q2TAM5> , <http://purl.uniprot.org/uniprot/E9PQS6> , <http://purl.uniprot.org/uniprot/E9PKV4> , <http://purl.uniprot.org/uniprot/E9PI38> , <http://purl.uniprot.org/uniprot/E9PRX2> , <http://purl.uniprot.org/uniprot/E9PNV4> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/5970> .

<https://identifiers.org/pubmed/1844873>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "1844873" ;
        dcterms:isPartOf    <https://identifiers.org/ncbigene/1543> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/1844873> .

<http://rdf.wikipathways.org/Pathway/WP2586_r142469/WP/Interaction/idabee82eb>
        rdf:type          wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2586_r142469> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2586_r142469/Interaction/idabee82eb> .

<https://identifiers.org/ensembl/ENSG00000169032>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "MAP2K1" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000169032> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000169032" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2586_r142469> , <http://rdf.wikipathways.org/Pathway/WP2586_r142469/WP/Interaction/idfb358ab4> , <http://rdf.wikipathways.org/Pathway/WP2586_r142469/WP/Interaction/idacb2b077> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000169032> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/5604> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/MAP2K1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/B4DFY5> , <https://identifiers.org/uniprot/A0A8I5KYS7> , <https://identifiers.org/uniprot/H3BRW9> , <https://identifiers.org/uniprot/A0A8I5QJC1> , <https://identifiers.org/uniprot/A0A8I5KYB4> , <https://identifiers.org/uniprot/A0A8I5QJP8> , <https://identifiers.org/uniprot/A0A8I5KVF6> , <https://identifiers.org/uniprot/A0A8I5QJ96> , <https://identifiers.org/uniprot/A0A8I5KRX5> , <https://identifiers.org/uniprot/A0A8I5QJL9> , <https://identifiers.org/uniprot/A0A8I5KXN4> , <https://identifiers.org/uniprot/A4QPA9> , <https://identifiers.org/uniprot/Q02750> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18030793> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2586_r142469/DataNode/b98df> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A8I5QJ96> , <http://purl.uniprot.org/uniprot/A0A8I5QJL9> , <http://purl.uniprot.org/uniprot/A4QPA9> , <http://purl.uniprot.org/uniprot/A0A8I5KYB4> , <http://purl.uniprot.org/uniprot/B4DFY5> , <http://purl.uniprot.org/uniprot/A0A8I5QJC1> , <http://purl.uniprot.org/uniprot/A0A8I5KXN4> , <http://purl.uniprot.org/uniprot/A0A8I5KVF6> , <http://purl.uniprot.org/uniprot/A0A8I5KYS7> , <http://purl.uniprot.org/uniprot/A0A8I5QJP8> , <http://purl.uniprot.org/uniprot/H3BRW9> , <http://purl.uniprot.org/uniprot/A0A8I5KRX5> , <http://purl.uniprot.org/uniprot/Q02750> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000169032> .

<https://identifiers.org/ncbigene/1017>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "CDK2" ;
        dc:identifier       <https://identifiers.org/ncbigene/1017> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "1017" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2586_r142469/WP/Interaction/id72845f06> , <http://rdf.wikipathways.org/Pathway/WP2586_r142469/WP/Interaction/faf4e> , <http://rdf.wikipathways.org/Pathway/WP2586_r142469/WP/Interaction/idc40b6454> , <https://identifiers.org/wikipathways/WP2586_r142469> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000123374> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/1017> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/CDK2> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A024RB10> , <https://identifiers.org/uniprot/G3V317> , <https://identifiers.org/uniprot/P24941> , <https://identifiers.org/uniprot/E7ESI2> , <https://identifiers.org/uniprot/G3V5T9> , <https://identifiers.org/uniprot/A0A024RB77> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2586_r142469/DataNode/f6591> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/G3V317> , <http://purl.uniprot.org/uniprot/P24941> , <http://purl.uniprot.org/uniprot/G3V5T9> , <http://purl.uniprot.org/uniprot/E7ESI2> , <http://purl.uniprot.org/uniprot/A0A024RB10> , <http://purl.uniprot.org/uniprot/A0A024RB77> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/1017> .

<http://rdf.wikipathways.org/Pathway/WP2586_r142469/Complex/df20e>
        rdf:type          wp:Complex , wp:DataNode ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2586_r142469> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2586_r142469/Group/df20e> ;
        wp:participants   <https://identifiers.org/ncbigene/5970> , <https://identifiers.org/ncbigene/4790> , <https://identifiers.org/ncbigene/2033> , <https://identifiers.org/ncbigene/84722> .

<https://identifiers.org/ncbigene/1543>
        rdf:type            wp:DataNode , wp:Protein , wp:GeneProduct ;
        rdfs:label          "CYP1A1" ;
        dc:identifier       <https://identifiers.org/ncbigene/1543> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "1543" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2586_r142469> , <http://rdf.wikipathways.org/Pathway/WP2586_r142469/WP/Interaction/idac09c4e3> , <http://rdf.wikipathways.org/Pathway/WP2586_r142469/Complex/b4164> , <http://rdf.wikipathways.org/Pathway/WP2586_r142469/WP/Interaction/b5103> , <http://rdf.wikipathways.org/Pathway/WP2586_r142469/WP/Interaction/id8cff4ef7> ;
        dcterms:references  <https://identifiers.org/pubmed/1844873> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000140465> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/1543> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/CYP1A1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A4F3V8> , <https://identifiers.org/uniprot/P04798> , <https://identifiers.org/uniprot/A0N0X8> , <https://identifiers.org/uniprot/E7EMT5> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2586_r142469/DataNode/c52eb> , <http://rdf.wikipathways.org/Pathway/WP2586_r142469/DataNode/fba25> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P04798> , <http://purl.uniprot.org/uniprot/A0N0X8> , <http://purl.uniprot.org/uniprot/A4F3V8> , <http://purl.uniprot.org/uniprot/E7EMT5> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/1543> .
