@prefix biopax:  <http://www.biopax.org/release/biopax-level3.owl#> .
@prefix cito:    <http://purl.org/spar/cito/> .
@prefix dc:      <http://purl.org/dc/elements/1.1/> .
@prefix dcterms: <http://purl.org/dc/terms/> .
@prefix foaf:    <http://xmlns.com/foaf/0.1/> .
@prefix freq:    <http://purl.org/cld/freq/> .
@prefix gpml:    <http://vocabularies.wikipathways.org/gpml#> .
@prefix obo:     <http://purl.obolibrary.org/obo/> .
@prefix owl:     <http://www.w3.org/2002/07/owl#> .
@prefix pav:     <http://purl.org/pav/> .
@prefix prov:    <http://www.w3.org/ns/prov#> .
@prefix rdf:     <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix rdfs:    <http://www.w3.org/2000/01/rdf-schema#> .
@prefix skos:    <http://www.w3.org/2004/02/skos/core#> .
@prefix void:    <http://rdfs.org/ns/void#> .
@prefix wp:      <http://vocabularies.wikipathways.org/wp#> .
@prefix wprdf:   <http://rdf.wikipathways.org/> .
@prefix xsd:     <http://www.w3.org/2001/XMLSchema#> .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/WP/Interaction/id7171d355>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4674_r142545> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id7171d355> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000064012> , <https://identifiers.org/ensembl/ENSG00000141510> ;
        wp:source         <https://identifiers.org/ensembl/ENSG00000141510> ;
        wp:target         <https://identifiers.org/ensembl/ENSG00000064012> .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/ComplexBinding/f595e>
        rdf:type          wp:ComplexBinding , wp:Binding , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4674_r142545> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Group/f595e> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000162409> , <https://identifiers.org/ensembl/ENSG00000132356> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Complex/f595e> .

<https://identifiers.org/ensembl/ENSG00000151247>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "EIF4E" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000151247> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000151247" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4674_r142545/WP/Interaction/id4ff3e838> , <https://identifiers.org/wikipathways/WP4674_r142545> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000151247> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/1977> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/EIF4E> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/D6RFJ3> , <https://identifiers.org/uniprot/P06730> , <https://identifiers.org/uniprot/H0Y8J7> , <https://identifiers.org/uniprot/X5D7E3> , <https://identifiers.org/uniprot/D6RBW1> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q5408696> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/af357> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/D6RFJ3> , <http://purl.uniprot.org/uniprot/H0Y8J7> , <http://purl.uniprot.org/uniprot/P06730> , <http://purl.uniprot.org/uniprot/D6RBW1> , <http://purl.uniprot.org/uniprot/X5D7E3> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000151247> .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/WP/Interaction/id793259d9>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4674_r142545> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id793259d9> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000124762> , <https://identifiers.org/ensembl/ENSG00000141510> ;
        wp:source         <https://identifiers.org/ensembl/ENSG00000141510> ;
        wp:target         <https://identifiers.org/ensembl/ENSG00000124762> .

<https://identifiers.org/ensembl/ENSG00000168036>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "CTNNB1" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000168036> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000168036" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4674_r142545/WP/Interaction/id5178da0d> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/WP/Interaction/id870ef7e2> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/WP/Interaction/id9196c758> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/WP/Interaction/idc4bc37ee> , <https://identifiers.org/wikipathways/WP4674_r142545> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000168036> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/1499> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/CTNNB1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A2R8Y5C3> , <https://identifiers.org/uniprot/A0A2R8Y804> , <https://identifiers.org/uniprot/C9IZ65> , <https://identifiers.org/uniprot/A0A2R8Y6G0> , <https://identifiers.org/uniprot/A0A024R2Q3> , <https://identifiers.org/uniprot/A0A2R8Y5Z1> , <https://identifiers.org/uniprot/A0A2R8Y750> , <https://identifiers.org/uniprot/A0A2R8Y543> , <https://identifiers.org/uniprot/B4DGU4> , <https://identifiers.org/uniprot/A0A2R8YG06> , <https://identifiers.org/uniprot/A0A2R8YCH5> , <https://identifiers.org/uniprot/P35222> , <https://identifiers.org/uniprot/A0A2R8Y7Z0> , <https://identifiers.org/uniprot/A0A2R8Y815> , <https://identifiers.org/uniprot/A0A2R8Y5A3> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q14902794> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/b43d0> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/B4DGU4> , <http://purl.uniprot.org/uniprot/A0A2R8Y6G0> , <http://purl.uniprot.org/uniprot/A0A2R8Y5A3> , <http://purl.uniprot.org/uniprot/A0A2R8Y5Z1> , <http://purl.uniprot.org/uniprot/A0A2R8Y5C3> , <http://purl.uniprot.org/uniprot/A0A2R8Y7Z0> , <http://purl.uniprot.org/uniprot/A0A2R8Y750> , <http://purl.uniprot.org/uniprot/A0A2R8Y815> , <http://purl.uniprot.org/uniprot/A0A2R8YCH5> , <http://purl.uniprot.org/uniprot/P35222> , <http://purl.uniprot.org/uniprot/A0A2R8Y543> , <http://purl.uniprot.org/uniprot/A0A2R8Y804> , <http://purl.uniprot.org/uniprot/A0A2R8YG06> , <http://purl.uniprot.org/uniprot/A0A024R2Q3> , <http://purl.uniprot.org/uniprot/C9IZ65> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000168036> .

<https://identifiers.org/pmc/PMC11265978>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed Central" ;
        dcterms:identifier  "PMC11265978" ;
        cito:cites          <https://identifiers.org/wikipathways/WP4674> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/PMC11265978> .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/WP/Interaction/idcf61ccc8>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4674_r142545> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/idcf61ccc8> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000064012> , <https://identifiers.org/ensembl/ENSG00000168040> ;
        wp:source         <https://identifiers.org/ensembl/ENSG00000168040> ;
        wp:target         <https://identifiers.org/ensembl/ENSG00000064012> .

<https://identifiers.org/ensembl/ENSG00000105810>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "CDK6" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000105810> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000105810" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Complex/d6359> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000105810> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/1021> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/CDK6> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q00534> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q14911762> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/e0738> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q00534> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000105810> .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Complex/baa75>
        rdf:type          wp:Complex , wp:DataNode ;
        rdfs:label        "PI3K class 1a" ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4674_r142545> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Group/baa75> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000145675> , <https://identifiers.org/ensembl/ENSG00000105647> , <https://identifiers.org/ensembl/ENSG00000051382> , <https://identifiers.org/ensembl/ENSG00000121879> .

<https://identifiers.org/ensembl/ENSG00000105851>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "PIK3CG" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000105851> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000105851" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Complex/d848a> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000105851> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/5294> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/PIK3CG> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/P48736> , <https://identifiers.org/uniprot/A0A024R720> , <https://identifiers.org/uniprot/E9PDN7> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18030551> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/f1772> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P48736> , <http://purl.uniprot.org/uniprot/A0A024R720> , <http://purl.uniprot.org/uniprot/E9PDN7> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000105851> .

<https://identifiers.org/ensembl/ENSG00000141506>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "PIK3R5" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000141506> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000141506" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Complex/d848a> , <https://identifiers.org/wikipathways/WP4674_r142545> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000141506> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/23533> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/PIK3R5> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/L7RT34> , <https://identifiers.org/uniprot/J3KT66> , <https://identifiers.org/uniprot/Q8WYR1> , <https://identifiers.org/uniprot/J3KRE9> , <https://identifiers.org/uniprot/J3KSW1> , <https://identifiers.org/uniprot/X6R3K3> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18037249> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/cc574> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/J3KT66> , <http://purl.uniprot.org/uniprot/J3KSW1> , <http://purl.uniprot.org/uniprot/Q8WYR1> , <http://purl.uniprot.org/uniprot/L7RT34> , <http://purl.uniprot.org/uniprot/J3KRE9> , <http://purl.uniprot.org/uniprot/X6R3K3> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000141506> .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Complex/d6359>
        rdf:type          wp:Complex , wp:DataNode ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4674_r142545> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Group/d6359> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000105810> , <https://identifiers.org/ensembl/ENSG00000135446> , <https://identifiers.org/ensembl/ENSG00000124762> .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/ComplexBinding/fe6d3>
        rdf:type          wp:Interaction , wp:Binding , wp:ComplexBinding ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4674_r142545> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Group/fe6d3> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000119487> , <https://identifiers.org/ensembl/ENSG00000164327> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Complex/fe6d3> , <https://identifiers.org/ensembl/ENSG00000167965> , <https://identifiers.org/ensembl/ENSG00000198793> .

<https://identifiers.org/ensembl/ENSG00000051382>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "PIK3CB" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000051382> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000051382" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Complex/baa75> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000051382> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/5291> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/PIK3CB> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/H7C565> , <https://identifiers.org/uniprot/H7C5C3> , <https://identifiers.org/uniprot/H0Y871> , <https://identifiers.org/uniprot/C9JYX0> , <https://identifiers.org/uniprot/H7C527> , <https://identifiers.org/uniprot/C9J345> , <https://identifiers.org/uniprot/P42338> , <https://identifiers.org/uniprot/F8WDJ8> , <https://identifiers.org/uniprot/Q68DL0> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18030549> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/d8776> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P42338> , <http://purl.uniprot.org/uniprot/Q68DL0> , <http://purl.uniprot.org/uniprot/H7C527> , <http://purl.uniprot.org/uniprot/H7C565> , <http://purl.uniprot.org/uniprot/H7C5C3> , <http://purl.uniprot.org/uniprot/C9J345> , <http://purl.uniprot.org/uniprot/H0Y871> , <http://purl.uniprot.org/uniprot/C9JYX0> , <http://purl.uniprot.org/uniprot/F8WDJ8> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000051382> .

<https://identifiers.org/pmc/PMC12448840>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed Central" ;
        dcterms:identifier  "PMC12448840" ;
        cito:cites          <https://identifiers.org/wikipathways/WP4674> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/PMC12448840> .

<https://identifiers.org/ensembl/ENSG00000121879>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "PIK3CA" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000121879> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000121879" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Complex/baa75> , <https://identifiers.org/wikipathways/WP4674_r142545> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000121879> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/5290> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/PIK3CA> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/P42336> , <https://identifiers.org/uniprot/A0A2R8Y2F6> , <https://identifiers.org/uniprot/A0A6Q8PGV1> , <https://identifiers.org/uniprot/C9JAM9> , <https://identifiers.org/uniprot/C9J951> , <https://identifiers.org/uniprot/A0A6Q8PGN9> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q14887700> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/b92bc> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/C9J951> , <http://purl.uniprot.org/uniprot/C9JAM9> , <http://purl.uniprot.org/uniprot/P42336> , <http://purl.uniprot.org/uniprot/A0A2R8Y2F6> , <http://purl.uniprot.org/uniprot/A0A6Q8PGV1> , <http://purl.uniprot.org/uniprot/A0A6Q8PGN9> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000121879> .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Complex/f77f0>
        rdf:type          wp:Complex , wp:DataNode ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4674_r142545> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Group/f77f0> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000165699> , <https://identifiers.org/ensembl/ENSG00000103197> .

<https://identifiers.org/ensembl/ENSG00000064012>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "CASP8" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000064012> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000064012" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4674_r142545/WP/Interaction/id4d578d10> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/WP/Interaction/idcf61ccc8> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/WP/Interaction/id7171d355> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/WP/Interaction/id19ff6cd6> , <https://identifiers.org/wikipathways/WP4674_r142545> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000064012> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/841> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/CASP8> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/F8WF39> , <https://identifiers.org/uniprot/A0A8Q3SI66> , <https://identifiers.org/uniprot/E7EQ01> , <https://identifiers.org/uniprot/E7EVN1> , <https://identifiers.org/uniprot/C9JB29> , <https://identifiers.org/uniprot/Q14790> , <https://identifiers.org/uniprot/A0A024R3Z8> , <https://identifiers.org/uniprot/A0A8Q3WKY8> , <https://identifiers.org/uniprot/H7C0E2> , <https://identifiers.org/uniprot/E7ETB7> , <https://identifiers.org/uniprot/A0A8Q3SID9> , <https://identifiers.org/uniprot/E7EQ06> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q14911965> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/fbf7f> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/cf932> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q14790> , <http://purl.uniprot.org/uniprot/E7EVN1> , <http://purl.uniprot.org/uniprot/A0A8Q3SID9> , <http://purl.uniprot.org/uniprot/E7EQ01> , <http://purl.uniprot.org/uniprot/A0A8Q3WKY8> , <http://purl.uniprot.org/uniprot/C9JB29> , <http://purl.uniprot.org/uniprot/A0A024R3Z8> , <http://purl.uniprot.org/uniprot/F8WF39> , <http://purl.uniprot.org/uniprot/H7C0E2> , <http://purl.uniprot.org/uniprot/E7ETB7> , <http://purl.uniprot.org/uniprot/E7EQ06> , <http://purl.uniprot.org/uniprot/A0A8Q3SI66> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000064012> .

<https://identifiers.org/ensembl/ENSG00000173039>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "RELA" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000173039> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000173039" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Complex/af5e4> , <https://identifiers.org/wikipathways/WP4674_r142545> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000173039> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/5970> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/RELA> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/E9PJZ9> , <https://identifiers.org/uniprot/E9PJR1> , <https://identifiers.org/uniprot/Q2TAM5> , <https://identifiers.org/uniprot/E9PRX2> , <https://identifiers.org/uniprot/H0YCB4> , <https://identifiers.org/uniprot/Q04206> , <https://identifiers.org/uniprot/E9PKV4> , <https://identifiers.org/uniprot/E9PKH5> , <https://identifiers.org/uniprot/E9PSE4> , <https://identifiers.org/uniprot/E9PNV4> , <https://identifiers.org/uniprot/E9PNK5> , <https://identifiers.org/uniprot/A0A087X0W8> , <https://identifiers.org/uniprot/E9PMD5> , <https://identifiers.org/uniprot/E9PM47> , <https://identifiers.org/uniprot/E9PI38> , <https://identifiers.org/uniprot/E9PQS6> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q15326052> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/null> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/E9PM47> , <http://purl.uniprot.org/uniprot/E9PNV4> , <http://purl.uniprot.org/uniprot/A0A087X0W8> , <http://purl.uniprot.org/uniprot/E9PI38> , <http://purl.uniprot.org/uniprot/E9PNK5> , <http://purl.uniprot.org/uniprot/E9PJZ9> , <http://purl.uniprot.org/uniprot/E9PKH5> , <http://purl.uniprot.org/uniprot/E9PKV4> , <http://purl.uniprot.org/uniprot/H0YCB4> , <http://purl.uniprot.org/uniprot/E9PMD5> , <http://purl.uniprot.org/uniprot/E9PQS6> , <http://purl.uniprot.org/uniprot/E9PRX2> , <http://purl.uniprot.org/uniprot/Q2TAM5> , <http://purl.uniprot.org/uniprot/Q04206> , <http://purl.uniprot.org/uniprot/E9PJR1> , <http://purl.uniprot.org/uniprot/E9PSE4> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000173039> .

<https://identifiers.org/ensembl/ENSG00000161021>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "MAML1" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000161021> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000161021" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4674_r142545> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000161021> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/9794> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/MAML1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q92585> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18034681> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/f8503> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q92585> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000161021> .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Complex/f595e>
        rdf:type          wp:Complex , wp:DataNode ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4674_r142545> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Group/f595e> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000162409> , <https://identifiers.org/ensembl/ENSG00000132356> .

<https://identifiers.org/ensembl/ENSG00000106615>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "RHEB" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000106615> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000106615" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4674_r142545> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000106615> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/6009> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/RHEB> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q15382> , <https://identifiers.org/uniprot/C9J469> , <https://identifiers.org/uniprot/C9J931> , <https://identifiers.org/uniprot/A0A090N900> , <https://identifiers.org/uniprot/F8WBL3> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18031127> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/a1e2b> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q15382> , <http://purl.uniprot.org/uniprot/A0A090N900> , <http://purl.uniprot.org/uniprot/C9J469> , <http://purl.uniprot.org/uniprot/F8WBL3> , <http://purl.uniprot.org/uniprot/C9J931> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000106615> .

<https://identifiers.org/ensembl/ENSG00000147889>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "p16 INK4a (CDKN2A)" , "p14 ARF  (CDKN2A)" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000147889> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000147889" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4674_r142545/WP/Interaction/id29256dcf> , <https://identifiers.org/wikipathways/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/WP/Interaction/id1209ef14> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000147889> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/1029> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/CDKN2A> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q8N726> , <https://identifiers.org/uniprot/P42771> , <https://identifiers.org/uniprot/K7PML8> , <https://identifiers.org/uniprot/J3QRG6> , <https://identifiers.org/uniprot/K7ES20> , <https://identifiers.org/uniprot/K7ENC6> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q5009957> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/ee18e> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/ee3b2> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/K7ENC6> , <http://purl.uniprot.org/uniprot/P42771> , <http://purl.uniprot.org/uniprot/J3QRG6> , <http://purl.uniprot.org/uniprot/K7PML8> , <http://purl.uniprot.org/uniprot/Q8N726> , <http://purl.uniprot.org/uniprot/K7ES20> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000147889> .

<https://identifiers.org/ensembl/ENSG00000036257>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "CUL3" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000036257> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000036257" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Complex/e2561> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000036257> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/8452> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/CUL3> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q13618> , <https://identifiers.org/uniprot/A0A024R475> , <https://identifiers.org/uniprot/H7C399> , <https://identifiers.org/uniprot/A0A087X1R9> , <https://identifiers.org/uniprot/H7C1L6> , <https://identifiers.org/uniprot/H7C1J0> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18032944> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/de84f> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A087X1R9> , <http://purl.uniprot.org/uniprot/A0A024R475> , <http://purl.uniprot.org/uniprot/H7C1J0> , <http://purl.uniprot.org/uniprot/Q13618> , <http://purl.uniprot.org/uniprot/H7C1L6> , <http://purl.uniprot.org/uniprot/H7C399> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000036257> .

<https://identifiers.org/ensembl/ENSG00000083857>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "FAT1" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000083857> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000083857" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4674_r142545/WP/Interaction/id9196c758> , <https://identifiers.org/wikipathways/WP4674_r142545> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000083857> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/2195> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/FAT1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q14517> , <https://identifiers.org/uniprot/D6RCE4> , <https://identifiers.org/uniprot/H0Y9H4> , <https://identifiers.org/uniprot/D6RHE6> , <https://identifiers.org/uniprot/H0Y8F5> , <https://identifiers.org/uniprot/H0Y9C8> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q17927589> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/e2132> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q14517> , <http://purl.uniprot.org/uniprot/H0Y8F5> , <http://purl.uniprot.org/uniprot/H0Y9H4> , <http://purl.uniprot.org/uniprot/D6RCE4> , <http://purl.uniprot.org/uniprot/H0Y9C8> , <http://purl.uniprot.org/uniprot/D6RHE6> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000083857> .

<https://identifiers.org/ensembl/ENSG00000162924>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "REL" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000162924> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000162924" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Complex/af5e4> , <https://identifiers.org/wikipathways/WP4674_r142545> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000162924> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/5966> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/REL> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A8V8TMW2> , <https://identifiers.org/uniprot/A0A8V8TMU9> , <https://identifiers.org/uniprot/Q04864> , <https://identifiers.org/uniprot/A0A8V8TPL7> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18031085> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/e89aa> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/e6270> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A8V8TMU9> , <http://purl.uniprot.org/uniprot/A0A8V8TPL7> , <http://purl.uniprot.org/uniprot/A0A8V8TMW2> , <http://purl.uniprot.org/uniprot/Q04864> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000162924> .

<https://identifiers.org/chebi/CHEBI:68481>
        rdf:type            wp:DataNode , wp:Metabolite ;
        rdfs:label          "mTOR inhibitors" ;
        dc:identifier       <https://identifiers.org/chebi/CHEBI:68481> ;
        dc:source           "ChEBI" ;
        dcterms:identifier  "CHEBI:68481" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4674_r142545> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:68481> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q5282002> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/ee837> ;
        foaf:page           <https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:68481> .

<https://identifiers.org/ensembl/ENSG00000213281>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "NRAS" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000213281> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000213281" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4674_r142545> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000213281> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/4893> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/NRAS> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q5U091> , <https://identifiers.org/uniprot/P01111> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18030215> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/baa16> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P01111> , <http://purl.uniprot.org/uniprot/Q5U091> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000213281> .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/WP/Interaction/id9196c758>
        rdf:type          wp:Inhibition , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4674_r142545> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id9196c758> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000168036> , <https://identifiers.org/ensembl/ENSG00000083857> ;
        wp:source         <https://identifiers.org/ensembl/ENSG00000083857> ;
        wp:target         <https://identifiers.org/ensembl/ENSG00000168036> .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Complex/fe6d3>
        rdf:type          wp:Complex , wp:DataNode ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4674_r142545> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Group/fe6d3> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000164327> , <https://identifiers.org/ensembl/ENSG00000119487> , <https://identifiers.org/ensembl/ENSG00000198793> , <https://identifiers.org/ensembl/ENSG00000167965> .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Complex/e2561>
        rdf:type          wp:Complex , wp:DataNode ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4674_r142545> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Group/e2561> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000079999> , <https://identifiers.org/ensembl/ENSG00000036257> .

<https://identifiers.org/ensembl/ENSG00000199030>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "MIRLET7C" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000199030> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000199030" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4674_r142545> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000199030> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/406885> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/MIRLET7C> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18058002> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/b4b5d> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000199030> .

<https://identifiers.org/ensembl/ENSG00000133703>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "KRAS" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000133703> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000133703" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4674_r142545> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000133703> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/3845> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/KRAS> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/G3V4K2> , <https://identifiers.org/uniprot/G3V5T7> , <https://identifiers.org/uniprot/L7RSL8> , <https://identifiers.org/uniprot/A0A024RAV5> , <https://identifiers.org/uniprot/A0A8I5KUB5> , <https://identifiers.org/uniprot/A0A8I5KYH6> , <https://identifiers.org/uniprot/A0A8I5KQU3> , <https://identifiers.org/uniprot/A0A8I5KR86> , <https://identifiers.org/uniprot/A0A8I5KXN3> , <https://identifiers.org/uniprot/P01116> , <https://identifiers.org/uniprot/A0A8I5KQ21> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q20969980> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/e1de9> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A8I5KUB5> , <http://purl.uniprot.org/uniprot/L7RSL8> , <http://purl.uniprot.org/uniprot/P01116> , <http://purl.uniprot.org/uniprot/A0A8I5KXN3> , <http://purl.uniprot.org/uniprot/G3V4K2> , <http://purl.uniprot.org/uniprot/A0A8I5KYH6> , <http://purl.uniprot.org/uniprot/A0A8I5KR86> , <http://purl.uniprot.org/uniprot/A0A024RAV5> , <http://purl.uniprot.org/uniprot/A0A8I5KQU3> , <http://purl.uniprot.org/uniprot/A0A8I5KQ21> , <http://purl.uniprot.org/uniprot/G3V5T7> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000133703> .

<https://identifiers.org/pubmed/31695792>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "31695792" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4674_r142545/WP/Interaction/idc4bc37ee> , <https://identifiers.org/wikipathways/WP4674_r142545> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/31695792> .

<https://identifiers.org/pfam/PF00020>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "TNFR" ;
        dc:identifier       <https://identifiers.org/pfam/PF00020> ;
        dc:source           "Pfam" ;
        dcterms:identifier  "PF00020" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4674_r142545> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/cb00c> ;
        foaf:page           <https://pfam.xfam.org/family/PF00020/> .

<https://identifiers.org/ensembl/ENSG00000141646>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "SMAD4" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000141646> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000141646" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4674_r142545> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000141646> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/4089> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/SMAD4> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/K7ES96> , <https://identifiers.org/uniprot/K7EIU8> , <https://identifiers.org/uniprot/K7EL18> , <https://identifiers.org/uniprot/K7ENG1> , <https://identifiers.org/uniprot/K7ELK2> , <https://identifiers.org/uniprot/K7EIJ2> , <https://identifiers.org/uniprot/Q13485> , <https://identifiers.org/uniprot/K7EL15> , <https://identifiers.org/uniprot/A0A087WUF3> , <https://identifiers.org/uniprot/A0A024R274> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q14904154> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/a7c20> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A024R274> , <http://purl.uniprot.org/uniprot/K7ENG1> , <http://purl.uniprot.org/uniprot/K7ES96> , <http://purl.uniprot.org/uniprot/K7EIU8> , <http://purl.uniprot.org/uniprot/K7EL15> , <http://purl.uniprot.org/uniprot/A0A087WUF3> , <http://purl.uniprot.org/uniprot/Q13485> , <http://purl.uniprot.org/uniprot/K7EIJ2> , <http://purl.uniprot.org/uniprot/K7ELK2> , <http://purl.uniprot.org/uniprot/K7EL18> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000141646> .

<https://identifiers.org/ensembl/ENSG00000080546>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "SESN1" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000080546> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000080546" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4674_r142545> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000080546> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/27244> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/SESN1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q9Y6P5> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18038736> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/f82c2> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q9Y6P5> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000080546> .

<https://identifiers.org/ensembl/ENSG00000116044>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "NFE2L2" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000116044> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000116044" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4674_r142545/WP/Interaction/idc4bc37ee> , <https://identifiers.org/wikipathways/WP4674_r142545> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000116044> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/4780> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/NFE2L2> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A8V8TNS1> , <https://identifiers.org/uniprot/A0A8V8TPN5> , <https://identifiers.org/uniprot/A0A8V8TN41> , <https://identifiers.org/uniprot/K7EIW5> , <https://identifiers.org/uniprot/A0A8V8TNQ8> , <https://identifiers.org/uniprot/A0A8V8TPX0> , <https://identifiers.org/uniprot/C9J1A8> , <https://identifiers.org/uniprot/A0A8V8TQ20> , <https://identifiers.org/uniprot/K7ER33> , <https://identifiers.org/uniprot/A0A8V8TN85> , <https://identifiers.org/uniprot/A0A8V8TN51> , <https://identifiers.org/uniprot/A0A8V8TND9> , <https://identifiers.org/uniprot/A0A8V8TNI6> , <https://identifiers.org/uniprot/A0A8V8TPF4> , <https://identifiers.org/uniprot/A0A8V8TPI5> , <https://identifiers.org/uniprot/A0A8V8TNM0> , <https://identifiers.org/uniprot/C9J0Y1> , <https://identifiers.org/uniprot/A0A8V8TPC8> , <https://identifiers.org/uniprot/A0A8V8TPM0> , <https://identifiers.org/uniprot/A0A8V8TN40> , <https://identifiers.org/uniprot/Q16236> , <https://identifiers.org/uniprot/A0A8V8TN14> , <https://identifiers.org/uniprot/A0A8V8TNM5> , <https://identifiers.org/uniprot/A0A8V8TPF0> , <https://identifiers.org/uniprot/A0A8V8TPL6> , <https://identifiers.org/uniprot/A0A8V8TN31> , <https://identifiers.org/uniprot/A0A8V8TPA8> , <https://identifiers.org/uniprot/A0A8V8TNJ6> , <https://identifiers.org/uniprot/A0A8V8TPT8> , <https://identifiers.org/uniprot/H7C498> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18030088> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/efff3> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A8V8TN41> , <http://purl.uniprot.org/uniprot/A0A8V8TNM0> , <http://purl.uniprot.org/uniprot/A0A8V8TPA8> , <http://purl.uniprot.org/uniprot/A0A8V8TNS1> , <http://purl.uniprot.org/uniprot/Q16236> , <http://purl.uniprot.org/uniprot/A0A8V8TQ20> , <http://purl.uniprot.org/uniprot/A0A8V8TPL6> , <http://purl.uniprot.org/uniprot/A0A8V8TND9> , <http://purl.uniprot.org/uniprot/A0A8V8TNJ6> , <http://purl.uniprot.org/uniprot/A0A8V8TPI5> , <http://purl.uniprot.org/uniprot/A0A8V8TN85> , <http://purl.uniprot.org/uniprot/A0A8V8TPX0> , <http://purl.uniprot.org/uniprot/A0A8V8TNQ8> , <http://purl.uniprot.org/uniprot/C9J1A8> , <http://purl.uniprot.org/uniprot/A0A8V8TPM0> , <http://purl.uniprot.org/uniprot/A0A8V8TN31> , <http://purl.uniprot.org/uniprot/A0A8V8TPN5> , <http://purl.uniprot.org/uniprot/A0A8V8TPF4> , <http://purl.uniprot.org/uniprot/C9J0Y1> , <http://purl.uniprot.org/uniprot/A0A8V8TPF0> , <http://purl.uniprot.org/uniprot/A0A8V8TN51> , <http://purl.uniprot.org/uniprot/K7EIW5> , <http://purl.uniprot.org/uniprot/A0A8V8TNM5> , <http://purl.uniprot.org/uniprot/K7ER33> , <http://purl.uniprot.org/uniprot/A0A8V8TPC8> , <http://purl.uniprot.org/uniprot/A0A8V8TPT8> , <http://purl.uniprot.org/uniprot/H7C498> , <http://purl.uniprot.org/uniprot/A0A8V8TNI6> , <http://purl.uniprot.org/uniprot/A0A8V8TN40> , <http://purl.uniprot.org/uniprot/A0A8V8TN14> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000116044> .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/ComplexBinding/f77f0>
        rdf:type          wp:ComplexBinding , wp:Binding , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4674_r142545> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Group/f77f0> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000165699> , <https://identifiers.org/ensembl/ENSG00000103197> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Complex/f77f0> .

<https://identifiers.org/ncbigene/2064>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "ERBB2" ;
        dc:identifier       <https://identifiers.org/ncbigene/2064> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "2064" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4674_r142545> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000141736> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/2064> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/ERBB2> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/P04626> , <https://identifiers.org/uniprot/J3QRX1> , <https://identifiers.org/uniprot/B4DTR1> , <https://identifiers.org/uniprot/F5H1T4> , <https://identifiers.org/uniprot/X5DNK3> , <https://identifiers.org/uniprot/J3QL83> , <https://identifiers.org/uniprot/J3KRI9> , <https://identifiers.org/uniprot/J3QLV2> , <https://identifiers.org/uniprot/J3QLU9> , <https://identifiers.org/uniprot/J3QRJ7> , <https://identifiers.org/uniprot/J3KTI5> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/b1a41> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/J3KRI9> , <http://purl.uniprot.org/uniprot/J3KTI5> , <http://purl.uniprot.org/uniprot/P04626> , <http://purl.uniprot.org/uniprot/F5H1T4> , <http://purl.uniprot.org/uniprot/B4DTR1> , <http://purl.uniprot.org/uniprot/J3QLU9> , <http://purl.uniprot.org/uniprot/X5DNK3> , <http://purl.uniprot.org/uniprot/J3QRJ7> , <http://purl.uniprot.org/uniprot/J3QLV2> , <http://purl.uniprot.org/uniprot/J3QRX1> , <http://purl.uniprot.org/uniprot/J3QL83> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/2064> .

<https://identifiers.org/ensembl/ENSG00000139687>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "RB1" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000139687> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000139687" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/WP/Interaction/id5ef1a8e> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000139687> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/5925> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/RB1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A024RDV3> , <https://identifiers.org/uniprot/A0A3B3IS71> , <https://identifiers.org/uniprot/Q92728> , <https://identifiers.org/uniprot/P06400> , <https://identifiers.org/uniprot/A0A2R8YFL6> , <https://identifiers.org/uniprot/A0A2R8Y743> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q40108> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/b23bb> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P06400> , <http://purl.uniprot.org/uniprot/A0A2R8Y743> , <http://purl.uniprot.org/uniprot/A0A3B3IS71> , <http://purl.uniprot.org/uniprot/A0A2R8YFL6> , <http://purl.uniprot.org/uniprot/A0A024RDV3> , <http://purl.uniprot.org/uniprot/Q92728> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000139687> .

<https://identifiers.org/wikipathways/WP4674_r142545>
        rdf:type               wp:Pathway , skos:Collection ;
        dc:identifier          <https://identifiers.org/wikipathways/WP4674> ;
        dc:source              "WikiPathways" ;
        dc:title               "Head and neck squamous cell carcinoma"@en ;
        dcterms:description    "HNSCC, which includes malignant squamous lesions arising in the oral cavity, larynx and pharynx, is the seventh most common cancer in the world.\nHNSCC has a remarkable multiplicity and diversity of genetic alterations. Most genomic alterations in HNSCC converge in a handful of molecular pathways resulting in cell cycle deregulation, genomic instability, cell differentiation defects, and persistent mitogenic signaling, the latter involving aberrant PI3K/mTOR pathway activation thereby rendering HNSCC responsive to PI3K/mTOR inhibitors.\n\nPathway is based on [Fig 1 from Iglesias-Bartolome et al](https://europepmc.org/articles/PMC4348071), [Fig 5 from Li et al](https://www.nature.com/articles/nature14129) and [Fig 33-3 from Clinicalgate](https://clinicalgate.com/the-molecular-pathogenesis-of-head-and-neck-cancer/). \n\nDescription is modified from [Iglesias-Bartolome et al](https://europepmc.org/articles/PMC4348071).\nProtein phosphorylation sites were added based on information from PhosphoSitePlus (R), www.phosphosite.org." ;
        dcterms:identifier     "WP4674" ;
        dcterms:references     <https://identifiers.org/pubmed/31695792> , <https://identifiers.org/pubmed/25514926> , <https://identifiers.org/pubmed/23847349> ;
        cito:cites             <https://identifiers.org/pubmed/31695792> , <https://identifiers.org/pubmed/23847349> , <https://identifiers.org/pubmed/25514926> ;
        wp:diseaseOntologyTag  obo:DOID_1542 ;
        wp:isAbout             <http://rdf.wikipathways.org/Pathway/WP4674_r142545> ;
        wp:ontologyTag         obo:DOID_1542 , wp:Curation:Diseases , wp:Curation:AnalysisCollection , wp:Curation:CPTAC , obo:PW_0000605 , obo:PW_0000013 ;
        wp:organism            obo:NCBITaxon_9606 ;
        wp:organismName        "Homo sapiens" ;
        wp:pathwayOntologyTag  obo:PW_0000605 , obo:PW_0000013 ;
        foaf:img               <https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=svg&pwTitle=Pathway:WP4674&oldid=142545> , <https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=png&pwTitle=Pathway:WP4674&oldid=142545> ;
        foaf:page              <http://www.wikipathways.org/instance/WP4674_r142545> .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/WP/Interaction/id62611738>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4674_r142545> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id62611738> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000137154> , <https://identifiers.org/ncbigene/6199> ;
        wp:source         <https://identifiers.org/ncbigene/6199> ;
        wp:target         <https://identifiers.org/ensembl/ENSG00000137154> .

<https://identifiers.org/ensembl/ENSG00000101412>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "E2F1" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000101412> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000101412" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/WP/Interaction/id5ef1a8e> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000101412> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/1869> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/E2F1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q01094> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q15333016> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/f0d17> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q01094> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000101412> .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/WP/Interaction/id4ff3e838>
        rdf:type          wp:Inhibition , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4674_r142545> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id4ff3e838> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000151247> , <https://identifiers.org/ncbigene/1978> ;
        wp:source         <https://identifiers.org/ncbigene/1978> ;
        wp:target         <https://identifiers.org/ensembl/ENSG00000151247> .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/ComplexBinding/d848a>
        rdf:type          wp:ComplexBinding , wp:Binding , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4674_r142545> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Group/d848a> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000141506> , <https://identifiers.org/ensembl/ENSG00000105851> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Complex/d848a> .

<https://identifiers.org/ensembl/ENSG00000130766>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "SESN2" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000130766> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000130766" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4674_r142545> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000130766> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/83667> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/SESN2> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/P58004> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/fc56d> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P58004> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000130766> .

<https://identifiers.org/ensembl/ENSG00000146648>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "EGFR" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000146648> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000146648" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4674_r142545> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000146648> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/1956> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/EGFR> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/C9JYS6> , <https://identifiers.org/uniprot/P00533> , <https://identifiers.org/uniprot/A0A8V8TPW8> , <https://identifiers.org/uniprot/Q504U8> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q14865565> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/fc80d> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P00533> , <http://purl.uniprot.org/uniprot/A0A8V8TPW8> , <http://purl.uniprot.org/uniprot/C9JYS6> , <http://purl.uniprot.org/uniprot/Q504U8> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000146648> .

<https://identifiers.org/ensembl/ENSG00000109320>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "NFKB1" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000109320> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000109320" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Complex/af5e4> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000109320> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/4790> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/NFKB1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A8V8TLB2> , <https://identifiers.org/uniprot/D6RC45> , <https://identifiers.org/uniprot/A0A494C157> , <https://identifiers.org/uniprot/P19838> , <https://identifiers.org/uniprot/D6RH30> , <https://identifiers.org/uniprot/A0A494C1E9> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q15317427> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/c2075> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A494C1E9> , <http://purl.uniprot.org/uniprot/A0A494C157> , <http://purl.uniprot.org/uniprot/D6RC45> , <http://purl.uniprot.org/uniprot/A0A8V8TLB2> , <http://purl.uniprot.org/uniprot/P19838> , <http://purl.uniprot.org/uniprot/D6RH30> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000109320> .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/ComplexBinding/e2561>
        rdf:type          wp:ComplexBinding , wp:Binding , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4674_r142545> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Group/e2561> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000079999> , <https://identifiers.org/ensembl/ENSG00000036257> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Complex/e2561> .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Complex/af5e4>
        rdf:type          wp:Complex , wp:DataNode ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4674_r142545> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Group/af5e4> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000109320> , <https://identifiers.org/ensembl/ENSG00000077150> , <https://identifiers.org/ensembl/ENSG00000173039> , <https://identifiers.org/ensembl/ENSG00000162924> .

<https://identifiers.org/chebi/CHEBI:16618>
        rdf:type            wp:Metabolite , wp:DataNode ;
        rdfs:label          "PIP3" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/RQQIRMLGKSPXSE-UQPICLANSA-N> ;
        dc:identifier       <https://identifiers.org/chebi/CHEBI:16618> ;
        dc:source           "ChEBI" ;
        dcterms:identifier  "CHEBI:16618" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4674_r142545/WP/Interaction/c94ca> , <https://identifiers.org/wikipathways/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/WP/Interaction/e2a5f> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:16618> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/34980938> ;
        wp:bdbHmdb          <https://identifiers.org/hmdb/HMDB0004249> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/RQQIRMLGKSPXSE-UQPICLANSA-N> ;
        wp:bdbKeggCompound  <https://identifiers.org/kegg.compound/C05981> ;
        wp:bdbLipidMaps     <https://identifiers.org/lipidmaps/LMGP09010000> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q28797898> , <http://www.wikidata.org/entity/Q130305209> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/d2be7> ;
        owl:sameAs          <https://www.lipidmaps.org/rdf/LMGP09010000> ;
        foaf:page           <https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:16618> .

<https://identifiers.org/ensembl/ENSG00000162409>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "PRKAA2" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000162409> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000162409" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Complex/f595e> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000162409> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/5563> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/PRKAA2> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/P54646> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18030757> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/de75e> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P54646> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000162409> .

<https://identifiers.org/ensembl/ENSG00000077150>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "NFKB2" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000077150> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000077150" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Complex/af5e4> , <https://identifiers.org/wikipathways/WP4674_r142545> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000077150> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/4791> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/NFKB2> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q00653> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18030102> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/ad1b2> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q00653> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000077150> .

<https://identifiers.org/ensembl/ENSG00000148400>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "NOTCH1" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000148400> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000148400" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4674_r142545> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000148400> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/4851> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/NOTCH1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A7P0T9V1> , <https://identifiers.org/uniprot/A0A7P0Z4H9> , <https://identifiers.org/uniprot/A0A7P0TBG2> , <https://identifiers.org/uniprot/A0A7P0TB20> , <https://identifiers.org/uniprot/A0A7P0T8U6> , <https://identifiers.org/uniprot/A0A7P0TA56> , <https://identifiers.org/uniprot/P46531> , <https://identifiers.org/uniprot/A0A7P0TAK8> , <https://identifiers.org/uniprot/A0A7P0T8W1> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18252685> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/dcfec> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P46531> , <http://purl.uniprot.org/uniprot/A0A7P0TB20> , <http://purl.uniprot.org/uniprot/A0A7P0TAK8> , <http://purl.uniprot.org/uniprot/A0A7P0TBG2> , <http://purl.uniprot.org/uniprot/A0A7P0T9V1> , <http://purl.uniprot.org/uniprot/A0A7P0TA56> , <http://purl.uniprot.org/uniprot/A0A7P0T8U6> , <http://purl.uniprot.org/uniprot/A0A7P0T8W1> , <http://purl.uniprot.org/uniprot/A0A7P0Z4H9> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000148400> .

<https://identifiers.org/ensembl/ENSG00000088832>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "FKBP1A" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000088832> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000088832" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4674_r142545> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000088832> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/2280> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/FKBP1A> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/F6T7Q3> , <https://identifiers.org/uniprot/A0A087WTS4> , <https://identifiers.org/uniprot/P62942> , <https://identifiers.org/uniprot/Q1JUQ3> , <https://identifiers.org/uniprot/A0A7I2V3S6> , <https://identifiers.org/uniprot/Q1JUQ5> , <https://identifiers.org/uniprot/Q5W0X3> , <https://identifiers.org/uniprot/A0A087WZM5> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q17928420> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/a1b32> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P62942> , <http://purl.uniprot.org/uniprot/Q1JUQ3> , <http://purl.uniprot.org/uniprot/F6T7Q3> , <http://purl.uniprot.org/uniprot/A0A087WTS4> , <http://purl.uniprot.org/uniprot/Q5W0X3> , <http://purl.uniprot.org/uniprot/A0A087WZM5> , <http://purl.uniprot.org/uniprot/A0A7I2V3S6> , <http://purl.uniprot.org/uniprot/Q1JUQ5> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000088832> .

<https://identifiers.org/chebi/CHEBI:9168>
        rdf:type            wp:Metabolite , wp:DataNode ;
        rdfs:label          "Rapamycin" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/QFJCIRLUMZQUOT-HPLJOQBZSA-N> ;
        dc:identifier       <https://identifiers.org/chebi/CHEBI:9168> ;
        dc:source           "ChEBI" ;
        dcterms:identifier  "CHEBI:9168" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4674_r142545> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:9168> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/10482078> ;
        wp:bdbHmdb          <https://identifiers.org/hmdb/HMDB0015015> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/QFJCIRLUMZQUOT-HPLJOQBZSA-N> ;
        wp:bdbKeggCompound  <https://identifiers.org/kegg.compound/C07909> ;
        wp:bdbLipidMaps     <https://identifiers.org/lipidmaps/LMPK06000003> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID5284616> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q32089> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/c6073> ;
        owl:sameAs          <https://www.lipidmaps.org/rdf/LMPK06000003> ;
        foaf:page           <https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:9168> .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/WP/Interaction/id870ef7e2>
        rdf:type          wp:Inhibition , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4674_r142545> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id870ef7e2> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000168036> , <https://identifiers.org/ensembl/ENSG00000129474> ;
        wp:source         <https://identifiers.org/ensembl/ENSG00000129474> ;
        wp:target         <https://identifiers.org/ensembl/ENSG00000168036> .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/WP/Interaction/id19ff6cd6>
        rdf:type          wp:Inhibition , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4674_r142545> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id19ff6cd6> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000064012> , <https://identifiers.org/ensembl/ENSG00000110330> ;
        wp:source         <https://identifiers.org/ensembl/ENSG00000110330> ;
        wp:target         <https://identifiers.org/ensembl/ENSG00000064012> .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Complex/d848a>
        rdf:type          wp:Complex , wp:DataNode ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4674_r142545> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Group/d848a> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000141506> , <https://identifiers.org/ensembl/ENSG00000105851> .

obo:NCBITaxon_9606  obo:NCIT_C179773  "9606" .

<https://identifiers.org/ensembl/ENSG00000119487>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "MAPKAP1" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000119487> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000119487" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Complex/fe6d3> , <https://identifiers.org/wikipathways/WP4674_r142545> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000119487> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/79109> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/MAPKAP1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/E9PGB8> , <https://identifiers.org/uniprot/Q9BPZ7> , <https://identifiers.org/uniprot/B1AMB2> , <https://identifiers.org/uniprot/B1AMA5> , <https://identifiers.org/uniprot/B1AMB1> , <https://identifiers.org/uniprot/A0A024R863> , <https://identifiers.org/uniprot/B1AMA6> , <https://identifiers.org/uniprot/H0Y7F8> , <https://identifiers.org/uniprot/H0Y866> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18046011> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/f2627> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/H0Y7F8> , <http://purl.uniprot.org/uniprot/B1AMB1> , <http://purl.uniprot.org/uniprot/E9PGB8> , <http://purl.uniprot.org/uniprot/H0Y866> , <http://purl.uniprot.org/uniprot/B1AMA5> , <http://purl.uniprot.org/uniprot/B1AMB2> , <http://purl.uniprot.org/uniprot/A0A024R863> , <http://purl.uniprot.org/uniprot/B1AMA6> , <http://purl.uniprot.org/uniprot/Q9BPZ7> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000119487> .

<https://identifiers.org/chebi/CHEBI:50914>
        rdf:type            wp:DataNode , wp:Metabolite ;
        rdfs:label          "PI3K inhibitors" ;
        dc:identifier       <https://identifiers.org/chebi/CHEBI:50914> ;
        dc:source           "ChEBI" ;
        dcterms:identifier  "CHEBI:50914" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4674_r142545> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:50914> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q7187512> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/fc7b8> ;
        foaf:page           <https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:50914> .

<https://identifiers.org/ensembl/ENSG00000077782>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "FGFR1" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000077782> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000077782" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4674_r142545> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000077782> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/2260> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/FGFR1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/E9PN14> , <https://identifiers.org/uniprot/P11362> , <https://identifiers.org/uniprot/C9J205> , <https://identifiers.org/uniprot/A0A6I8PRY1> , <https://identifiers.org/uniprot/H0YE20> , <https://identifiers.org/uniprot/E9PKX3> , <https://identifiers.org/uniprot/A0A994J419> , <https://identifiers.org/uniprot/A0A8I3B1S4> , <https://identifiers.org/uniprot/A0A0S2Z3Q6> , <https://identifiers.org/uniprot/E9PKF2> , <https://identifiers.org/uniprot/C9J1L5> , <https://identifiers.org/uniprot/A0A0S2Z3T4> , <https://identifiers.org/uniprot/A0A6I8PTV4> , <https://identifiers.org/uniprot/E9PQ40> , <https://identifiers.org/uniprot/B5A958> , <https://identifiers.org/uniprot/E9PNM3> , <https://identifiers.org/uniprot/A0A804HIF1> , <https://identifiers.org/uniprot/A0A3B3ISD1> , <https://identifiers.org/uniprot/E9PKV7> , <https://identifiers.org/uniprot/E7EU09> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q14914258> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/ef180> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/C9J205> , <http://purl.uniprot.org/uniprot/E9PNM3> , <http://purl.uniprot.org/uniprot/A0A0S2Z3Q6> , <http://purl.uniprot.org/uniprot/A0A8I3B1S4> , <http://purl.uniprot.org/uniprot/B5A958> , <http://purl.uniprot.org/uniprot/A0A804HIF1> , <http://purl.uniprot.org/uniprot/A0A0S2Z3T4> , <http://purl.uniprot.org/uniprot/A0A6I8PTV4> , <http://purl.uniprot.org/uniprot/E9PKF2> , <http://purl.uniprot.org/uniprot/A0A994J419> , <http://purl.uniprot.org/uniprot/A0A6I8PRY1> , <http://purl.uniprot.org/uniprot/E9PN14> , <http://purl.uniprot.org/uniprot/P11362> , <http://purl.uniprot.org/uniprot/E9PKV7> , <http://purl.uniprot.org/uniprot/H0YE20> , <http://purl.uniprot.org/uniprot/A0A3B3ISD1> , <http://purl.uniprot.org/uniprot/E9PQ40> , <http://purl.uniprot.org/uniprot/E9PKX3> , <http://purl.uniprot.org/uniprot/C9J1L5> , <http://purl.uniprot.org/uniprot/E7EU09> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000077782> .

<https://identifiers.org/ensembl/ENSG00000079999>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "KEAP1" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000079999> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000079999" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Complex/e2561> , <https://identifiers.org/wikipathways/WP4674_r142545> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000079999> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/9817> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/KEAP1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/K7EJD8> , <https://identifiers.org/uniprot/K7EQX2> , <https://identifiers.org/uniprot/K7EPZ3> , <https://identifiers.org/uniprot/A0A024R7C0> , <https://identifiers.org/uniprot/K7EJ49> , <https://identifiers.org/uniprot/Q14145> , <https://identifiers.org/uniprot/K7ESE0> , <https://identifiers.org/uniprot/K7EMY1> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18034700> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/a8698> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/K7EJ49> , <http://purl.uniprot.org/uniprot/K7ESE0> , <http://purl.uniprot.org/uniprot/Q14145> , <http://purl.uniprot.org/uniprot/K7EQX2> , <http://purl.uniprot.org/uniprot/K7EJD8> , <http://purl.uniprot.org/uniprot/K7EPZ3> , <http://purl.uniprot.org/uniprot/A0A024R7C0> , <http://purl.uniprot.org/uniprot/K7EMY1> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000079999> .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/ComplexBinding/af5e4>
        rdf:type          wp:Binding , wp:Interaction , wp:ComplexBinding ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4674_r142545> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Group/af5e4> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000109320> , <https://identifiers.org/ensembl/ENSG00000173039> , <https://identifiers.org/ensembl/ENSG00000162924> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Complex/af5e4> , <https://identifiers.org/ensembl/ENSG00000077150> .

<https://identifiers.org/ensembl/ENSG00000124762>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "CDKN1A" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000124762> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000124762" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4674_r142545/WP/Interaction/id2db3d091> , <https://identifiers.org/wikipathways/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/WP/Interaction/id793259d9> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Complex/d6359> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000124762> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/1026> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/CDKN1A> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/P38936> , <https://identifiers.org/uniprot/A0A024RCX5> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q14902453> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/dcfe8> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P38936> , <http://purl.uniprot.org/uniprot/A0A024RCX5> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000124762> .

<https://identifiers.org/ensembl/ENSG00000164796>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "CSMD3" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000164796> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000164796" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4674_r142545> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000164796> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/114788> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/CSMD3> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q7Z407> , <https://identifiers.org/uniprot/H7BXX0> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18049062> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/fd4dd> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/H7BXX0> , <http://purl.uniprot.org/uniprot/Q7Z407> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000164796> .

<https://identifiers.org/ensembl/ENSG00000129474>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "AJUBA" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000129474> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000129474" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4674_r142545/WP/Interaction/id870ef7e2> , <https://identifiers.org/wikipathways/WP4674_r142545> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000129474> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/84962> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/AJUBA> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/G3V481> , <https://identifiers.org/uniprot/G3V5F5> , <https://identifiers.org/uniprot/H0YJL9> , <https://identifiers.org/uniprot/Q96IF1> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18047922> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/c0dd4> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q96IF1> , <http://purl.uniprot.org/uniprot/G3V481> , <http://purl.uniprot.org/uniprot/H0YJL9> , <http://purl.uniprot.org/uniprot/G3V5F5> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000129474> .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/WP/Interaction/id2db3d091>
        rdf:type          wp:Inhibition , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4674_r142545> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id2db3d091> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000135446> , <https://identifiers.org/ensembl/ENSG00000124762> ;
        wp:source         <https://identifiers.org/ensembl/ENSG00000124762> ;
        wp:target         <https://identifiers.org/ensembl/ENSG00000135446> .

<https://identifiers.org/ensembl/ENSG00000117595>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "IRF6" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000117595> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000117595" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4674_r142545/WP/Interaction/id1cf06f6b> , <https://identifiers.org/wikipathways/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/WP/Interaction/id9cf21b4e> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000117595> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/3664> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/IRF6> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A2R8YHF3> , <https://identifiers.org/uniprot/G0Z349> , <https://identifiers.org/uniprot/O14896> , <https://identifiers.org/uniprot/B1AJU4> , <https://identifiers.org/uniprot/A0A8Q3WL17> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q14890118> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/f7569> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/B1AJU4> , <http://purl.uniprot.org/uniprot/A0A2R8YHF3> , <http://purl.uniprot.org/uniprot/O14896> , <http://purl.uniprot.org/uniprot/G0Z349> , <http://purl.uniprot.org/uniprot/A0A8Q3WL17> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000117595> .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/WP/Interaction/id1209ef14>
        rdf:type          wp:Inhibition , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4674_r142545> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id1209ef14> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000141510> , <https://identifiers.org/ensembl/ENSG00000147889> ;
        wp:source         <https://identifiers.org/ensembl/ENSG00000147889> ;
        wp:target         <https://identifiers.org/ensembl/ENSG00000141510> .

<https://identifiers.org/ensembl/ENSG00000105647>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "PIK3R2" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000105647> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000105647" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Complex/baa75> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000105647> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/5296> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/PIK3R2> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/O00459> , <https://identifiers.org/uniprot/A0A7I2U3A3> , <https://identifiers.org/uniprot/A0A087X257> , <https://identifiers.org/uniprot/A0A5F9ZHY3> , <https://identifiers.org/uniprot/V9GYJ4> , <https://identifiers.org/uniprot/E9PFP1> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/bc0b1> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/O00459> , <http://purl.uniprot.org/uniprot/V9GYJ4> , <http://purl.uniprot.org/uniprot/A0A5F9ZHY3> , <http://purl.uniprot.org/uniprot/E9PFP1> , <http://purl.uniprot.org/uniprot/A0A087X257> , <http://purl.uniprot.org/uniprot/A0A7I2U3A3> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000105647> .

<https://doi.org/10.47717%2Fturkjsurg.2025.2025-3-33>
        rdf:type            wp:PublicationReference ;
        dc:source           "DOI" ;
        dcterms:identifier  "10.47717/turkjsurg.2025.2025-3-33" ;
        cito:cites          <https://identifiers.org/wikipathways/WP4674> .

<https://identifiers.org/ncbigene/6199>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "RPS6KB2" ;
        dc:identifier       <https://identifiers.org/ncbigene/6199> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "6199" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/WP/Interaction/id62611738> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000175634> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/6199> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/RPS6KB2> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/R4GN47> , <https://identifiers.org/uniprot/Q9UBS0> , <https://identifiers.org/uniprot/E9PQF6> , <https://identifiers.org/uniprot/G3V2F1> , <https://identifiers.org/uniprot/E9PIP7> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/e1afd> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q9UBS0> , <http://purl.uniprot.org/uniprot/E9PIP7> , <http://purl.uniprot.org/uniprot/E9PQF6> , <http://purl.uniprot.org/uniprot/R4GN47> , <http://purl.uniprot.org/uniprot/G3V2F1> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/6199> .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/WP/Interaction/id83f023a5>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4674_r142545> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id83f023a5> ;
        wp:participants   <https://identifiers.org/wikipathways/WP254> , <https://identifiers.org/ensembl/ENSG00000141510> ;
        wp:source         <https://identifiers.org/ensembl/ENSG00000141510> ;
        wp:target         <https://identifiers.org/wikipathways/WP254> .

<https://identifiers.org/ensembl/ENSG00000134250>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "NOTCH2" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000134250> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000134250" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4674_r142545/WP/Interaction/id5178da0d> , <https://identifiers.org/wikipathways/WP4674_r142545> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000134250> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/4853> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/NOTCH2> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A494C1U9> , <https://identifiers.org/uniprot/A0A1W2PQQ5> , <https://identifiers.org/uniprot/Q04721> , <https://identifiers.org/uniprot/A0A494C1H8> , <https://identifiers.org/uniprot/A0A494C049> , <https://identifiers.org/uniprot/A0A494C1F1> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18030183> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/d1507> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A1W2PQQ5> , <http://purl.uniprot.org/uniprot/A0A494C049> , <http://purl.uniprot.org/uniprot/A0A494C1F1> , <http://purl.uniprot.org/uniprot/Q04721> , <http://purl.uniprot.org/uniprot/A0A494C1U9> , <http://purl.uniprot.org/uniprot/A0A494C1H8> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000134250> .

<https://identifiers.org/ensembl/ENSG00000137154>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "RPS6" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000137154> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000137154" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/WP/Interaction/id62611738> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000137154> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/6194> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/RPS6> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A2A3R5> , <https://identifiers.org/uniprot/P62753> , <https://identifiers.org/uniprot/A2A3R6> , <https://identifiers.org/uniprot/A2A3R7> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q7322419> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/b9db3> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A2A3R5> , <http://purl.uniprot.org/uniprot/A2A3R7> , <http://purl.uniprot.org/uniprot/A2A3R6> , <http://purl.uniprot.org/uniprot/P62753> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000137154> .

<https://identifiers.org/ensembl/ENSG00000198793>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "MTOR" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000198793> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000198793" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Complex/fe6d3> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Complex/a29ba> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000198793> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/2475> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/MTOR> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A8V8TRG9> , <https://identifiers.org/uniprot/A0A8V8TR74> , <https://identifiers.org/uniprot/A0A8V8TQN3> , <https://identifiers.org/uniprot/A0A8V8TQM6> , <https://identifiers.org/uniprot/A0A8V8TQ52> , <https://identifiers.org/uniprot/P42345> , <https://identifiers.org/uniprot/A0A8V8TQP2> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q14876086> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/c0391> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/f46ee> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P42345> , <http://purl.uniprot.org/uniprot/A0A8V8TQP2> , <http://purl.uniprot.org/uniprot/A0A8V8TQ52> , <http://purl.uniprot.org/uniprot/A0A8V8TQM6> , <http://purl.uniprot.org/uniprot/A0A8V8TRG9> , <http://purl.uniprot.org/uniprot/A0A8V8TR74> , <http://purl.uniprot.org/uniprot/A0A8V8TQN3> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000198793> .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/WP/Interaction/id29256dcf>
        rdf:type          wp:Inhibition , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4674_r142545> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id29256dcf> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000110092> , <https://identifiers.org/ensembl/ENSG00000147889> ;
        wp:source         <https://identifiers.org/ensembl/ENSG00000147889> ;
        wp:target         <https://identifiers.org/ensembl/ENSG00000110092> .

<https://identifiers.org/ensembl/ENSG00000145675>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "PIK3R1" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000145675> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000145675" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Complex/baa75> , <https://identifiers.org/wikipathways/WP4674_r142545> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000145675> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/5295> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/PIK3R1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/B3KWZ7> , <https://identifiers.org/uniprot/E5RK66> , <https://identifiers.org/uniprot/H0YBC2> , <https://identifiers.org/uniprot/A0A8V8TMF9> , <https://identifiers.org/uniprot/H0YB27> , <https://identifiers.org/uniprot/P27986> , <https://identifiers.org/uniprot/A0A8V8TL14> , <https://identifiers.org/uniprot/E5RHI0> , <https://identifiers.org/uniprot/A0A8V8TMF4> , <https://identifiers.org/uniprot/A0A8V8TL10> , <https://identifiers.org/uniprot/A0A8V8TLF1> , <https://identifiers.org/uniprot/A0A8V8TME9> , <https://identifiers.org/uniprot/A0A8V8TL31> , <https://identifiers.org/uniprot/A0A8V8TLE6> , <https://identifiers.org/uniprot/E5RJY0> , <https://identifiers.org/uniprot/A0A2X0SFG1> , <https://identifiers.org/uniprot/E5RGI8> , <https://identifiers.org/uniprot/A0A8V8TLF7> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q20969988> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/af720> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/E5RK66> , <http://purl.uniprot.org/uniprot/A0A8V8TMF9> , <http://purl.uniprot.org/uniprot/A0A8V8TMF4> , <http://purl.uniprot.org/uniprot/B3KWZ7> , <http://purl.uniprot.org/uniprot/A0A8V8TL10> , <http://purl.uniprot.org/uniprot/A0A8V8TL14> , <http://purl.uniprot.org/uniprot/A0A2X0SFG1> , <http://purl.uniprot.org/uniprot/A0A8V8TME9> , <http://purl.uniprot.org/uniprot/E5RHI0> , <http://purl.uniprot.org/uniprot/H0YBC2> , <http://purl.uniprot.org/uniprot/E5RJY0> , <http://purl.uniprot.org/uniprot/A0A8V8TL31> , <http://purl.uniprot.org/uniprot/A0A8V8TLF1> , <http://purl.uniprot.org/uniprot/A0A8V8TLE6> , <http://purl.uniprot.org/uniprot/A0A8V8TLF7> , <http://purl.uniprot.org/uniprot/E5RGI8> , <http://purl.uniprot.org/uniprot/H0YB27> , <http://purl.uniprot.org/uniprot/P27986> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000145675> .

<https://identifiers.org/wikipathways/WP254>
        rdf:type            wp:DataNode , wp:Pathway ;
        rdfs:label          "Apoptosis" ;
        dc:identifier       <https://identifiers.org/wikipathways/WP254> ;
        dc:source           "WikiPathways" ;
        dcterms:identifier  "WP254" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4674_r142545/WP/Interaction/id4d578d10> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/WP/Interaction/id83f023a5> , <https://identifiers.org/wikipathways/WP4674_r142545> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/b173b> ;
        foaf:page           <https://www.wikipathways.org/instance/WP254> .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/WP/Interaction/c94ca>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4674_r142545> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/c94ca> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000140992> , <https://identifiers.org/chebi/CHEBI:16618> ;
        wp:source         <https://identifiers.org/chebi/CHEBI:16618> ;
        wp:target         <https://identifiers.org/ensembl/ENSG00000140992> .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/WP/Interaction/e2a5f>
        rdf:type          wp:Inhibition , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4674_r142545> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/e2a5f> ;
        wp:participants   <https://identifiers.org/chebi/CHEBI:16618> , <https://identifiers.org/ensembl/ENSG00000171862> ;
        wp:source         <https://identifiers.org/ensembl/ENSG00000171862> ;
        wp:target         <https://identifiers.org/chebi/CHEBI:16618> .

<https://identifiers.org/ensembl/ENSG00000112715>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "VEGFA" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000112715> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000112715" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4674_r142545> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000112715> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/7422> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/VEGFA> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/H0YBI8> , <https://identifiers.org/uniprot/A0A0A0MSH5> , <https://identifiers.org/uniprot/J3KPA4> , <https://identifiers.org/uniprot/A0A0A0MTB2> , <https://identifiers.org/uniprot/A0A0Y0IMM4> , <https://identifiers.org/uniprot/H3BLW8> , <https://identifiers.org/uniprot/A0A0A0MR43> , <https://identifiers.org/uniprot/P15692> , <https://identifiers.org/uniprot/A2A2V4> , <https://identifiers.org/uniprot/A0A024RD33> , <https://identifiers.org/uniprot/A0A5F9ZH41> , <https://identifiers.org/uniprot/A0A0A0MSI7> , <https://identifiers.org/uniprot/A0A024RD37> , <https://identifiers.org/uniprot/H0YBZ0> , <https://identifiers.org/uniprot/A0A0A0MSH7> , <https://identifiers.org/uniprot/A0A0A0MRQ4> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18032324> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/d8ba7> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/J3KPA4> , <http://purl.uniprot.org/uniprot/A0A024RD33> , <http://purl.uniprot.org/uniprot/H3BLW8> , <http://purl.uniprot.org/uniprot/A0A5F9ZH41> , <http://purl.uniprot.org/uniprot/A0A0A0MTB2> , <http://purl.uniprot.org/uniprot/H0YBZ0> , <http://purl.uniprot.org/uniprot/A0A0A0MSH5> , <http://purl.uniprot.org/uniprot/A2A2V4> , <http://purl.uniprot.org/uniprot/A0A0A0MRQ4> , <http://purl.uniprot.org/uniprot/A0A0A0MR43> , <http://purl.uniprot.org/uniprot/A0A0A0MSI7> , <http://purl.uniprot.org/uniprot/A0A0A0MSH7> , <http://purl.uniprot.org/uniprot/P15692> , <http://purl.uniprot.org/uniprot/A0A0Y0IMM4> , <http://purl.uniprot.org/uniprot/A0A024RD37> , <http://purl.uniprot.org/uniprot/H0YBI8> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000112715> .

<https://identifiers.org/ensembl/ENSG00000168040>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "FADD" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000168040> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000168040" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/WP/Interaction/idcf61ccc8> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000168040> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/8772> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/FADD> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q13158> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q14907137> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/e8b0f> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q13158> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000168040> .

<https://identifiers.org/ensembl/ENSG00000167965>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "MLST8" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000167965> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000167965" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Complex/fe6d3> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Complex/a29ba> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000167965> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/64223> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/MLST8> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/H3BPU5> , <https://identifiers.org/uniprot/H3BSZ4> , <https://identifiers.org/uniprot/A0A0A0MR05> , <https://identifiers.org/uniprot/H3BQ74> , <https://identifiers.org/uniprot/Q9BVC4> , <https://identifiers.org/uniprot/H3BR38> , <https://identifiers.org/uniprot/I3L2E7> , <https://identifiers.org/uniprot/H3BR25> , <https://identifiers.org/uniprot/H3BM50> , <https://identifiers.org/uniprot/H3BPT1> , <https://identifiers.org/uniprot/H3BN58> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18045615> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/c79f6> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/ca5cf> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/H3BPT1> , <http://purl.uniprot.org/uniprot/I3L2E7> , <http://purl.uniprot.org/uniprot/H3BR38> , <http://purl.uniprot.org/uniprot/H3BSZ4> , <http://purl.uniprot.org/uniprot/H3BR25> , <http://purl.uniprot.org/uniprot/H3BQ74> , <http://purl.uniprot.org/uniprot/A0A0A0MR05> , <http://purl.uniprot.org/uniprot/Q9BVC4> , <http://purl.uniprot.org/uniprot/H3BN58> , <http://purl.uniprot.org/uniprot/H3BPU5> , <http://purl.uniprot.org/uniprot/H3BM50> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000167965> .

<https://identifiers.org/pmc/PMC9614744>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed Central" ;
        dcterms:identifier  "PMC9614744" ;
        cito:cites          <https://identifiers.org/wikipathways/WP4674> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/PMC9614744> .

<https://identifiers.org/ensembl/ENSG00000164327>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "RICTOR" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000164327> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000164327" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Complex/fe6d3> , <https://identifiers.org/wikipathways/WP4674_r142545> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000164327> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/253260> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/RICTOR> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/D6R9S6> , <https://identifiers.org/uniprot/Q6R327> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18053691> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/c3a2d> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/D6R9S6> , <http://purl.uniprot.org/uniprot/Q6R327> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000164327> .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/WP/Interaction/id9cf21b4e>
        rdf:type          wp:Inhibition , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4674_r142545> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id9cf21b4e> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000073282> , <https://identifiers.org/ensembl/ENSG00000117595> ;
        wp:source         <https://identifiers.org/ensembl/ENSG00000117595> ;
        wp:target         <https://identifiers.org/ensembl/ENSG00000073282> .

<https://identifiers.org/ensembl/ENSG00000105221>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "AKT2" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000105221> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000105221" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4674_r142545> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000105221> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/208> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/AKT2> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/J3KT31> , <https://identifiers.org/uniprot/M0QZW8> , <https://identifiers.org/uniprot/M0R0P9> , <https://identifiers.org/uniprot/J3KSY8> , <https://identifiers.org/uniprot/J3KRI8> , <https://identifiers.org/uniprot/M0R283> , <https://identifiers.org/uniprot/E7EVP8> , <https://identifiers.org/uniprot/M0R275> , <https://identifiers.org/uniprot/J3QLS6> , <https://identifiers.org/uniprot/C9JC83> , <https://identifiers.org/uniprot/J3KTP4> , <https://identifiers.org/uniprot/A0A1B0GXA2> , <https://identifiers.org/uniprot/A0A5F9ZHJ8> , <https://identifiers.org/uniprot/J3QL45> , <https://identifiers.org/uniprot/M0QZK3> , <https://identifiers.org/uniprot/J3KTC6> , <https://identifiers.org/uniprot/A0A0A0MRF1> , <https://identifiers.org/uniprot/J3QKW1> , <https://identifiers.org/uniprot/C9J258> , <https://identifiers.org/uniprot/P31751> , <https://identifiers.org/uniprot/A8MX96> , <https://identifiers.org/uniprot/C9JHS6> , <https://identifiers.org/uniprot/C9JIF6> , <https://identifiers.org/uniprot/C9JIJ1> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q4652205> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/f924d> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/M0QZW8> , <http://purl.uniprot.org/uniprot/M0R0P9> , <http://purl.uniprot.org/uniprot/J3QL45> , <http://purl.uniprot.org/uniprot/J3QLS6> , <http://purl.uniprot.org/uniprot/C9JIJ1> , <http://purl.uniprot.org/uniprot/A0A5F9ZHJ8> , <http://purl.uniprot.org/uniprot/J3KRI8> , <http://purl.uniprot.org/uniprot/C9JC83> , <http://purl.uniprot.org/uniprot/M0R283> , <http://purl.uniprot.org/uniprot/A0A1B0GXA2> , <http://purl.uniprot.org/uniprot/P31751> , <http://purl.uniprot.org/uniprot/C9JIF6> , <http://purl.uniprot.org/uniprot/M0R275> , <http://purl.uniprot.org/uniprot/J3KT31> , <http://purl.uniprot.org/uniprot/M0QZK3> , <http://purl.uniprot.org/uniprot/C9JHS6> , <http://purl.uniprot.org/uniprot/J3KSY8> , <http://purl.uniprot.org/uniprot/J3KTC6> , <http://purl.uniprot.org/uniprot/C9J258> , <http://purl.uniprot.org/uniprot/J3QKW1> , <http://purl.uniprot.org/uniprot/A8MX96> , <http://purl.uniprot.org/uniprot/A0A0A0MRF1> , <http://purl.uniprot.org/uniprot/E7EVP8> , <http://purl.uniprot.org/uniprot/J3KTP4> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000105221> .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/Complex/a29ba>
        rdf:type          wp:Complex , wp:DataNode ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4674_r142545> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Group/a29ba> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000167965> , <https://identifiers.org/ensembl/ENSG00000141564> , <https://identifiers.org/ensembl/ENSG00000198793> .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/WP/Interaction/id1cf06f6b>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4674_r142545> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id1cf06f6b> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000117595> , <https://identifiers.org/ensembl/ENSG00000073282> ;
        wp:source         <https://identifiers.org/ensembl/ENSG00000073282> ;
        wp:target         <https://identifiers.org/ensembl/ENSG00000117595> .

<https://identifiers.org/ensembl/ENSG00000174775>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "HRAS" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000174775> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000174775" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4674_r142545> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000174775> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/3265> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/HRAS> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/P01112> , <https://identifiers.org/uniprot/A0A804HJ06> , <https://identifiers.org/uniprot/X5D945> , <https://identifiers.org/uniprot/A0A804HKM6> , <https://identifiers.org/uniprot/A0A8C8MQR2> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/b54dd> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/X5D945> , <http://purl.uniprot.org/uniprot/P01112> , <http://purl.uniprot.org/uniprot/A0A804HJ06> , <http://purl.uniprot.org/uniprot/A0A804HKM6> , <http://purl.uniprot.org/uniprot/A0A8C8MQR2> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000174775> .

<https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=svg&pwTitle=Pathway:WP4674&oldid=142545>
        rdf:type        foaf:Image ;
        dcterms:format  "image/svg+xml" .

<https://identifiers.org/ensembl/ENSG00000140992>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "PDPK1" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000140992> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000140992" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4674_r142545/WP/Interaction/c94ca> , <https://identifiers.org/wikipathways/WP4674_r142545> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000140992> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/5170> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/PDPK1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/H3BQ10> , <https://identifiers.org/uniprot/H3BPW1> , <https://identifiers.org/uniprot/E9PER6> , <https://identifiers.org/uniprot/O15530> , <https://identifiers.org/uniprot/H3BNV5> , <https://identifiers.org/uniprot/H3BQA3> , <https://identifiers.org/uniprot/H3BPR5> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18030436> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/c1f22> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/H3BPR5> , <http://purl.uniprot.org/uniprot/H3BNV5> , <http://purl.uniprot.org/uniprot/H3BQA3> , <http://purl.uniprot.org/uniprot/H3BQ10> , <http://purl.uniprot.org/uniprot/O15530> , <http://purl.uniprot.org/uniprot/H3BPW1> , <http://purl.uniprot.org/uniprot/E9PER6> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000140992> .

<https://identifiers.org/ensembl/ENSG00000103197>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "TSC2" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000103197> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000103197" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Complex/f77f0> , <https://identifiers.org/wikipathways/WP4674_r142545> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000103197> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/7249> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/TSC2> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A2R8Y6C9> , <https://identifiers.org/uniprot/A0A2R8Y7X5> , <https://identifiers.org/uniprot/H3BQY7> , <https://identifiers.org/uniprot/Q5HYF7> , <https://identifiers.org/uniprot/A0A2R8YDR3> , <https://identifiers.org/uniprot/A0A2R8Y5F1> , <https://identifiers.org/uniprot/I3L3B1> , <https://identifiers.org/uniprot/A0A2R8YGU4> , <https://identifiers.org/uniprot/A0A2R8Y670> , <https://identifiers.org/uniprot/H3BMQ0> , <https://identifiers.org/uniprot/X5D7Q2> , <https://identifiers.org/uniprot/I3L134> , <https://identifiers.org/uniprot/A0A2R8YEJ8> , <https://identifiers.org/uniprot/A0A2R8YGE6> , <https://identifiers.org/uniprot/A0A2R8YCR8> , <https://identifiers.org/uniprot/P49815> , <https://identifiers.org/uniprot/A0A2R8YDZ2> , <https://identifiers.org/uniprot/A0A2R8Y692> , <https://identifiers.org/uniprot/H3BQK4> , <https://identifiers.org/uniprot/A0A2R8Y5B2> , <https://identifiers.org/uniprot/X5D2U8> , <https://identifiers.org/uniprot/A0A2R8YHA2> , <https://identifiers.org/uniprot/A0A2R8Y7C8> , <https://identifiers.org/uniprot/A0A2R8YGD6> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18032199> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/f4aa5> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A2R8Y5B2> , <http://purl.uniprot.org/uniprot/A0A2R8Y670> , <http://purl.uniprot.org/uniprot/A0A2R8Y7X5> , <http://purl.uniprot.org/uniprot/A0A2R8YGE6> , <http://purl.uniprot.org/uniprot/P49815> , <http://purl.uniprot.org/uniprot/A0A2R8YEJ8> , <http://purl.uniprot.org/uniprot/A0A2R8YCR8> , <http://purl.uniprot.org/uniprot/A0A2R8Y5F1> , <http://purl.uniprot.org/uniprot/H3BQY7> , <http://purl.uniprot.org/uniprot/Q5HYF7> , <http://purl.uniprot.org/uniprot/H3BMQ0> , <http://purl.uniprot.org/uniprot/A0A2R8YDR3> , <http://purl.uniprot.org/uniprot/A0A2R8YGD6> , <http://purl.uniprot.org/uniprot/A0A2R8Y7C8> , <http://purl.uniprot.org/uniprot/A0A2R8YHA2> , <http://purl.uniprot.org/uniprot/X5D7Q2> , <http://purl.uniprot.org/uniprot/H3BQK4> , <http://purl.uniprot.org/uniprot/A0A2R8Y6C9> , <http://purl.uniprot.org/uniprot/A0A2R8Y692> , <http://purl.uniprot.org/uniprot/I3L3B1> , <http://purl.uniprot.org/uniprot/A0A2R8YGU4> , <http://purl.uniprot.org/uniprot/I3L134> , <http://purl.uniprot.org/uniprot/A0A2R8YDZ2> , <http://purl.uniprot.org/uniprot/X5D2U8> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000103197> .

<https://identifiers.org/ensembl/ENSG00000141510>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "TP53" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000141510> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000141510" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4674_r142545/WP/Interaction/id793259d9> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/WP/Interaction/id1209ef14> , <https://identifiers.org/wikipathways/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/WP/Interaction/id7171d355> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/WP/Interaction/id83f023a5> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000141510> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/7157> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/TP53> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A087X1Q1> , <https://identifiers.org/uniprot/E7ESS1> , <https://identifiers.org/uniprot/H2EHT1> , <https://identifiers.org/uniprot/E9PFT5> , <https://identifiers.org/uniprot/A0A0U1RQC9> , <https://identifiers.org/uniprot/E9PCY9> , <https://identifiers.org/uniprot/I3L0W9> , <https://identifiers.org/uniprot/K7PPA8> , <https://identifiers.org/uniprot/J3KP33> , <https://identifiers.org/uniprot/S4R334> , <https://identifiers.org/uniprot/A0A087WXZ1> , <https://identifiers.org/uniprot/P04637> , <https://identifiers.org/uniprot/E7EMR6> , <https://identifiers.org/uniprot/A0A087WT22> , <https://identifiers.org/uniprot/E7EQX7> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q14818098> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/f688a> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P04637> , <http://purl.uniprot.org/uniprot/E7EQX7> , <http://purl.uniprot.org/uniprot/E7EMR6> , <http://purl.uniprot.org/uniprot/E9PCY9> , <http://purl.uniprot.org/uniprot/E9PFT5> , <http://purl.uniprot.org/uniprot/K7PPA8> , <http://purl.uniprot.org/uniprot/S4R334> , <http://purl.uniprot.org/uniprot/A0A087WXZ1> , <http://purl.uniprot.org/uniprot/A0A087X1Q1> , <http://purl.uniprot.org/uniprot/I3L0W9> , <http://purl.uniprot.org/uniprot/A0A087WT22> , <http://purl.uniprot.org/uniprot/A0A0U1RQC9> , <http://purl.uniprot.org/uniprot/J3KP33> , <http://purl.uniprot.org/uniprot/E7ESS1> , <http://purl.uniprot.org/uniprot/H2EHT1> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000141510> .

<https://identifiers.org/ensembl/ENSG00000118046>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "STK11" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000118046> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000118046" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4674_r142545> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000118046> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/6794> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/STK11> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A0S2Z4D1> , <https://identifiers.org/uniprot/A0A087WT72> , <https://identifiers.org/uniprot/K7EQN8> , <https://identifiers.org/uniprot/A0A1B0GUW2> , <https://identifiers.org/uniprot/Q15831> , <https://identifiers.org/uniprot/K7EMR0> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q2745322> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/e3b73> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A1B0GUW2> , <http://purl.uniprot.org/uniprot/K7EMR0> , <http://purl.uniprot.org/uniprot/K7EQN8> , <http://purl.uniprot.org/uniprot/A0A087WT72> , <http://purl.uniprot.org/uniprot/Q15831> , <http://purl.uniprot.org/uniprot/A0A0S2Z4D1> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000118046> .

<https://identifiers.org/ensembl/ENSG00000131323>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "TRAF3" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000131323> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000131323" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4674_r142545/WP/Interaction/id17ef750> , <https://identifiers.org/wikipathways/WP4674_r142545> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000131323> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/7187> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/TRAF3> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/H0YMI8> , <https://identifiers.org/uniprot/A6NHG8> , <https://identifiers.org/uniprot/H0YL26> , <https://identifiers.org/uniprot/H0YL25> , <https://identifiers.org/uniprot/Q13114> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18032095> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/bb45e> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A6NHG8> , <http://purl.uniprot.org/uniprot/H0YL26> , <http://purl.uniprot.org/uniprot/Q13114> , <http://purl.uniprot.org/uniprot/H0YL25> , <http://purl.uniprot.org/uniprot/H0YMI8> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000131323> .

<https://identifiers.org/ensembl/ENSG00000132356>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "PRKAA1" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000132356> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000132356" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Complex/f595e> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000132356> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/5562> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/PRKAA1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q96E92> , <https://identifiers.org/uniprot/Q13131> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18030756> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/fac79> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q96E92> , <http://purl.uniprot.org/uniprot/Q13131> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000132356> .

<https://identifiers.org/ensembl/ENSG00000141564>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "RPTOR" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000141564> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000141564" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Complex/a29ba> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000141564> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/57521> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/RPTOR> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A8V8TMD9> , <https://identifiers.org/uniprot/I3L2I3> , <https://identifiers.org/uniprot/I3L436> , <https://identifiers.org/uniprot/Q8N122> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18043110> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/d9e82> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q8N122> , <http://purl.uniprot.org/uniprot/I3L2I3> , <http://purl.uniprot.org/uniprot/I3L436> , <http://purl.uniprot.org/uniprot/A0A8V8TMD9> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000141564> .

<https://identifiers.org/ensembl/ENSG00000164362>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "TERT" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000164362> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000164362" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4674_r142545> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000164362> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/7015> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/TERT> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A590UK92> , <https://identifiers.org/uniprot/O14746> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q15315135> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/d8cd9> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A590UK92> , <http://purl.uniprot.org/uniprot/O14746> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000164362> .

<https://identifiers.org/wikidata/Q19484>
        rdf:type            wp:Metabolite , wp:DataNode ;
        rdfs:label          "Metformin" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/XZWYZXLIPXDOLR-UHFFFAOYSA-N> ;
        dc:identifier       <https://identifiers.org/wikidata/Q19484> ;
        dc:source           "Wikidata" ;
        dcterms:identifier  "Q19484" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4674_r142545> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:6801> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/3949> ;
        wp:bdbHmdb          <https://identifiers.org/hmdb/HMDB0001921> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/XZWYZXLIPXDOLR-UHFFFAOYSA-N> ;
        wp:bdbKeggCompound  <https://identifiers.org/kegg.compound/C07151> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID4091> , <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID155906370> , <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID152743144> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q19484> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/b9623> ;
        foaf:page           <https://scholia.toolforge.org/Q19484> .

<https://identifiers.org/ensembl/ENSG00000142208>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "AKT1" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000142208> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000142208" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4674_r142545> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000142208> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/207> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/AKT1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/G3V2I6> , <https://identifiers.org/uniprot/A0A804HJM6> , <https://identifiers.org/uniprot/A0A087WY56> , <https://identifiers.org/uniprot/G3V3X1> , <https://identifiers.org/uniprot/B0LPE5> , <https://identifiers.org/uniprot/P31749> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q17816452> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/b0ab3> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/G3V3X1> , <http://purl.uniprot.org/uniprot/G3V2I6> , <http://purl.uniprot.org/uniprot/A0A087WY56> , <http://purl.uniprot.org/uniprot/P31749> , <http://purl.uniprot.org/uniprot/A0A804HJM6> , <http://purl.uniprot.org/uniprot/B0LPE5> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000142208> .

<https://identifiers.org/wikipathways/WP4674>
        pav:hasVersion  <https://identifiers.org/wikipathways/WP4674_r142545> .

<https://identifiers.org/ensembl/ENSG00000110092>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "CCND1" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000110092> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000110092" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4674_r142545/WP/Interaction/id29256dcf> , <https://identifiers.org/wikipathways/WP4674_r142545> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000110092> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/595> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/CCND1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/F5H437> , <https://identifiers.org/uniprot/P24385> , <https://identifiers.org/uniprot/Q6FI00> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q15311861> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/cee2e> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q6FI00> , <http://purl.uniprot.org/uniprot/P24385> , <http://purl.uniprot.org/uniprot/F5H437> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000110092> .

<https://identifiers.org/ensembl/ENSG00000117020>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "AKT3" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000117020> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000117020" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4674_r142545> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000117020> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/10000> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/AKT3> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A5F9ZGY0> , <https://identifiers.org/uniprot/A0A5F9ZHU3> , <https://identifiers.org/uniprot/A0A5K1VW74> , <https://identifiers.org/uniprot/A0A5F9ZGZ4> , <https://identifiers.org/uniprot/A0A7P0T872> , <https://identifiers.org/uniprot/A0A5F9ZHA9> , <https://identifiers.org/uniprot/A0A7P0T8T9> , <https://identifiers.org/uniprot/A0A7P0TBJ6> , <https://identifiers.org/uniprot/A0A7P0TB29> , <https://identifiers.org/uniprot/Q9Y243> , <https://identifiers.org/uniprot/A0A7P0TB32> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18034943> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/cee43> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A5F9ZHU3> , <http://purl.uniprot.org/uniprot/Q9Y243> , <http://purl.uniprot.org/uniprot/A0A5K1VW74> , <http://purl.uniprot.org/uniprot/A0A5F9ZGY0> , <http://purl.uniprot.org/uniprot/A0A5F9ZHA9> , <http://purl.uniprot.org/uniprot/A0A7P0TBJ6> , <http://purl.uniprot.org/uniprot/A0A7P0TB32> , <http://purl.uniprot.org/uniprot/A0A5F9ZGZ4> , <http://purl.uniprot.org/uniprot/A0A7P0TB29> , <http://purl.uniprot.org/uniprot/A0A7P0T8T9> , <http://purl.uniprot.org/uniprot/A0A7P0T872> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000117020> .

<https://identifiers.org/ensembl/ENSG00000135446>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "CDK4" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000135446> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000135446" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Complex/d6359> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/WP/Interaction/id2db3d091> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000135446> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/1019> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/CDK4> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q96BE9> , <https://identifiers.org/uniprot/F8VYY1> , <https://identifiers.org/uniprot/F8VTV8> , <https://identifiers.org/uniprot/F8VZ51> , <https://identifiers.org/uniprot/F8VWX7> , <https://identifiers.org/uniprot/P11802> , <https://identifiers.org/uniprot/F8VYH9> , <https://identifiers.org/uniprot/F8W1L8> , <https://identifiers.org/uniprot/F8VZ13> , <https://identifiers.org/uniprot/F8VZZ0> , <https://identifiers.org/uniprot/F8VXD2> , <https://identifiers.org/uniprot/A0A024RBB6> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q14911754> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/e1aa5> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/F8VZ51> , <http://purl.uniprot.org/uniprot/F8W1L8> , <http://purl.uniprot.org/uniprot/F8VYH9> , <http://purl.uniprot.org/uniprot/F8VYY1> , <http://purl.uniprot.org/uniprot/F8VTV8> , <http://purl.uniprot.org/uniprot/F8VWX7> , <http://purl.uniprot.org/uniprot/Q96BE9> , <http://purl.uniprot.org/uniprot/P11802> , <http://purl.uniprot.org/uniprot/F8VZ13> , <http://purl.uniprot.org/uniprot/F8VZZ0> , <http://purl.uniprot.org/uniprot/F8VXD2> , <http://purl.uniprot.org/uniprot/A0A024RBB6> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000135446> .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/WP/Interaction/idc4bc37ee>
        rdf:type            wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4674_r142545> ;
        dcterms:references  <https://identifiers.org/pubmed/31695792> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/idc4bc37ee> ;
        wp:participants     <https://identifiers.org/ensembl/ENSG00000168036> , <https://identifiers.org/ensembl/ENSG00000116044> ;
        wp:source           <https://identifiers.org/ensembl/ENSG00000116044> ;
        wp:target           <https://identifiers.org/ensembl/ENSG00000168036> .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/ComplexBinding/a29ba>
        rdf:type          wp:ComplexBinding , wp:Binding , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4674_r142545> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Group/a29ba> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000167965> , <https://identifiers.org/ensembl/ENSG00000141564> , <https://identifiers.org/ensembl/ENSG00000198793> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Complex/a29ba> .

<https://identifiers.org/ensembl/ENSG00000168209>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "DDIT4" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000168209> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000168209" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4674_r142545> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000168209> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/54541> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/DDIT4> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A024QZQ6> , <https://identifiers.org/uniprot/Q9NX09> , <https://identifiers.org/uniprot/A0A7P0Z4M7> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18041085> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/a3f85> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A024QZQ6> , <http://purl.uniprot.org/uniprot/A0A7P0Z4M7> , <http://purl.uniprot.org/uniprot/Q9NX09> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000168209> .

<https://identifiers.org/pmc/PMC9675776>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed Central" ;
        dcterms:identifier  "PMC9675776" ;
        cito:cites          <https://identifiers.org/wikipathways/WP4674> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/PMC9675776> .

<https://identifiers.org/ensembl/ENSG00000133961>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "NUMB" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000133961> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000133961" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4674_r142545> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000133961> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/8650> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/NUMB> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/P49757> , <https://identifiers.org/uniprot/A0A024R6F4> , <https://identifiers.org/uniprot/G3V3R1> , <https://identifiers.org/uniprot/G3V4S6> , <https://identifiers.org/uniprot/A0A024R6C4> , <https://identifiers.org/uniprot/G3V3M5> , <https://identifiers.org/uniprot/G3V3Z8> , <https://identifiers.org/uniprot/A0A024R681> , <https://identifiers.org/uniprot/G3V433> , <https://identifiers.org/uniprot/A0A024R684> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18033185> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/d026f> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/G3V4S6> , <http://purl.uniprot.org/uniprot/G3V3Z8> , <http://purl.uniprot.org/uniprot/A0A024R6F4> , <http://purl.uniprot.org/uniprot/A0A024R681> , <http://purl.uniprot.org/uniprot/G3V3M5> , <http://purl.uniprot.org/uniprot/P49757> , <http://purl.uniprot.org/uniprot/A0A024R684> , <http://purl.uniprot.org/uniprot/A0A024R6C4> , <http://purl.uniprot.org/uniprot/G3V433> , <http://purl.uniprot.org/uniprot/G3V3R1> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000133961> .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/WP/Interaction/id17ef750>
        rdf:type          wp:Inhibition , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4674_r142545> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id17ef750> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000131323> , <https://identifiers.org/ensembl/ENSG00000110330> ;
        wp:source         <https://identifiers.org/ensembl/ENSG00000110330> ;
        wp:target         <https://identifiers.org/ensembl/ENSG00000131323> .

<https://identifiers.org/pubmed/25514926>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "25514926" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4674_r142545> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/25514926> .

<https://identifiers.org/ensembl/ENSG00000073282>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "TP63" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000073282> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000073282" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4674_r142545/WP/Interaction/id9cf21b4e> , <https://identifiers.org/wikipathways/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/WP/Interaction/id1cf06f6b> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000073282> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/8626> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/TP63> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/C9D7D0> , <https://identifiers.org/uniprot/C9JW72> , <https://identifiers.org/uniprot/A0A0S2Z4N5> , <https://identifiers.org/uniprot/Q9H3D4> , <https://identifiers.org/uniprot/A0A0S2Z4N6> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q15313986> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/b781d> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A0S2Z4N5> , <http://purl.uniprot.org/uniprot/A0A0S2Z4N6> , <http://purl.uniprot.org/uniprot/C9D7D0> , <http://purl.uniprot.org/uniprot/Q9H3D4> , <http://purl.uniprot.org/uniprot/C9JW72> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000073282> .

<https://identifiers.org/ensembl/ENSG00000163513>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "TGFBR2" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000163513> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000163513" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4674_r142545> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000163513> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/7048> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/TGFBR2> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/P37173> , <https://identifiers.org/uniprot/A3QNQ0> , <https://identifiers.org/uniprot/D2JYI1> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q14911585> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/f567f> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/D2JYI1> , <http://purl.uniprot.org/uniprot/P37173> , <http://purl.uniprot.org/uniprot/A3QNQ0> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000163513> .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/WP/Interaction/id5ef1a8e>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4674_r142545> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id5ef1a8e> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000101412> , <https://identifiers.org/ensembl/ENSG00000139687> ;
        wp:source         <https://identifiers.org/ensembl/ENSG00000139687> ;
        wp:target         <https://identifiers.org/ensembl/ENSG00000101412> .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/WP/Interaction/id4d578d10>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4674_r142545> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id4d578d10> ;
        wp:participants   <https://identifiers.org/wikipathways/WP254> , <https://identifiers.org/ensembl/ENSG00000064012> ;
        wp:source         <https://identifiers.org/ensembl/ENSG00000064012> ;
        wp:target         <https://identifiers.org/wikipathways/WP254> .

<https://identifiers.org/wikipathways/WP179>
        rdf:type            wp:Pathway , wp:DataNode ;
        rdfs:label          "Cell cycle" ;
        dc:identifier       <https://identifiers.org/wikipathways/WP179> ;
        dc:source           "WikiPathways" ;
        dcterms:identifier  "WP179" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4674_r142545> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/a809a> ;
        foaf:page           <https://www.wikipathways.org/instance/WP179> .

<https://identifiers.org/ncbigene/1978>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "EIF4EBP1" ;
        dc:identifier       <https://identifiers.org/ncbigene/1978> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "1978" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/WP/Interaction/id4ff3e838> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000187840> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/1978> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/EIF4EBP1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q13541> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/f04f4> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q13541> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/1978> .

<https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=png&pwTitle=Pathway:WP4674&oldid=142545>
        rdf:type        foaf:Image ;
        dcterms:format  "image/png" .

<https://identifiers.org/ensembl/ENSG00000165699>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "TSC1" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000165699> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000165699" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Complex/f77f0> , <https://identifiers.org/wikipathways/WP4674_r142545> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000165699> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/7248> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/TSC1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A2R8Y419> , <https://identifiers.org/uniprot/A0A2R8Y5U8> , <https://identifiers.org/uniprot/A0A2R8Y6W1> , <https://identifiers.org/uniprot/A0A2R8Y756> , <https://identifiers.org/uniprot/A0A2R8Y6T5> , <https://identifiers.org/uniprot/A0A2R8Y5F8> , <https://identifiers.org/uniprot/A0A2R8Y6S8> , <https://identifiers.org/uniprot/A0A2R8YGL0> , <https://identifiers.org/uniprot/Q92574> , <https://identifiers.org/uniprot/A0A2R8YD74> , <https://identifiers.org/uniprot/A0A2R8Y6N1> , <https://identifiers.org/uniprot/A0A2R8Y5M3> , <https://identifiers.org/uniprot/A0A2R8Y5J1> , <https://identifiers.org/uniprot/A0A2R8Y5S3> , <https://identifiers.org/uniprot/Q59IT9> , <https://identifiers.org/uniprot/A0A2R8Y5Q4> , <https://identifiers.org/uniprot/A0A2R8YGX7> , <https://identifiers.org/uniprot/A0A2R8Y6S1> , <https://identifiers.org/uniprot/X5D9D2> , <https://identifiers.org/uniprot/Q86WV8> , <https://identifiers.org/uniprot/A0A2R8YFV7> , <https://identifiers.org/uniprot/A0A2R8YEH9> , <https://identifiers.org/uniprot/A0A2R8Y7E9> , <https://identifiers.org/uniprot/A0A2R8Y5N2> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q14908113> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/a34d9> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A2R8YD74> , <http://purl.uniprot.org/uniprot/Q86WV8> , <http://purl.uniprot.org/uniprot/Q92574> , <http://purl.uniprot.org/uniprot/A0A2R8Y7E9> , <http://purl.uniprot.org/uniprot/A0A2R8YGL0> , <http://purl.uniprot.org/uniprot/X5D9D2> , <http://purl.uniprot.org/uniprot/A0A2R8YFV7> , <http://purl.uniprot.org/uniprot/A0A2R8Y6S8> , <http://purl.uniprot.org/uniprot/A0A2R8Y6W1> , <http://purl.uniprot.org/uniprot/A0A2R8YGX7> , <http://purl.uniprot.org/uniprot/A0A2R8Y5M3> , <http://purl.uniprot.org/uniprot/A0A2R8Y419> , <http://purl.uniprot.org/uniprot/A0A2R8Y756> , <http://purl.uniprot.org/uniprot/A0A2R8Y6S1> , <http://purl.uniprot.org/uniprot/A0A2R8Y6N1> , <http://purl.uniprot.org/uniprot/Q59IT9> , <http://purl.uniprot.org/uniprot/A0A2R8Y6T5> , <http://purl.uniprot.org/uniprot/A0A2R8Y5U8> , <http://purl.uniprot.org/uniprot/A0A2R8Y5S3> , <http://purl.uniprot.org/uniprot/A0A2R8Y5N2> , <http://purl.uniprot.org/uniprot/A0A2R8Y5J1> , <http://purl.uniprot.org/uniprot/A0A2R8Y5Q4> , <http://purl.uniprot.org/uniprot/A0A2R8Y5F8> , <http://purl.uniprot.org/uniprot/A0A2R8YEH9> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000165699> .

<https://identifiers.org/ensembl/ENSG00000068078>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "FGFR3" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000068078> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000068078" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4674_r142545> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000068078> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/2261> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/FGFR3> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/P22607> , <https://identifiers.org/uniprot/A0A7I2RW32> , <https://identifiers.org/uniprot/Q96T34> , <https://identifiers.org/uniprot/I6LM06> , <https://identifiers.org/uniprot/F8W9L4> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q14914358> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/b770e> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A7I2RW32> , <http://purl.uniprot.org/uniprot/F8W9L4> , <http://purl.uniprot.org/uniprot/P22607> , <http://purl.uniprot.org/uniprot/Q96T34> , <http://purl.uniprot.org/uniprot/I6LM06> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000068078> .

<https://identifiers.org/pubmed/23847349>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "23847349" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4674_r142545> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/23847349> .

<https://identifiers.org/hgnc.symbol/LTBR>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "LTBR" ;
        dc:identifier       <https://identifiers.org/hgnc.symbol/LTBR> ;
        dc:source           "HGNC" ;
        dcterms:identifier  "LTBR" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4674_r142545> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSSSCG00000000706> , <https://identifiers.org/ensembl/ENSG00000111321> , <https://identifiers.org/ensembl/ENSCAFG00845029256> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/4055> , <https://identifiers.org/ncbigene/486728> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/LTBR> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A5G2QIV0> , <https://identifiers.org/uniprot/F5H627> , <https://identifiers.org/uniprot/F5H6F8> , <https://identifiers.org/uniprot/A0A5G2Q934> , <https://identifiers.org/uniprot/A0A286ZKI9> , <https://identifiers.org/uniprot/F5H2E7> , <https://identifiers.org/uniprot/F5H1S5> , <https://identifiers.org/uniprot/P36941> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/d9f85> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A286ZKI9> , <http://purl.uniprot.org/uniprot/A0A5G2QIV0> , <http://purl.uniprot.org/uniprot/A0A5G2Q934> , <http://purl.uniprot.org/uniprot/F5H627> , <http://purl.uniprot.org/uniprot/F5H2E7> , <http://purl.uniprot.org/uniprot/F5H1S5> , <http://purl.uniprot.org/uniprot/P36941> , <http://purl.uniprot.org/uniprot/F5H6F8> ;
        foaf:page           <https://www.genenames.org/data/gene-symbol-report/#!/symbol/LTBR> .

<https://identifiers.org/ensembl/ENSG00000140443>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "IGF1R" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000140443> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000140443" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4674_r142545> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000140443> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/3480> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/IGF1R> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/P08069> , <https://identifiers.org/uniprot/H0YMJ5> , <https://identifiers.org/uniprot/H3BSZ8> , <https://identifiers.org/uniprot/H0YNR0> , <https://identifiers.org/uniprot/C9J5X1> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q14901457> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/f5e0d> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P08069> , <http://purl.uniprot.org/uniprot/H3BSZ8> , <http://purl.uniprot.org/uniprot/H0YMJ5> , <http://purl.uniprot.org/uniprot/H0YNR0> , <http://purl.uniprot.org/uniprot/C9J5X1> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000140443> .

<https://identifiers.org/ensembl/ENSG00000171862>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "PTEN" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000171862> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000171862" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4674_r142545> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/WP/Interaction/e2a5f> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000171862> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/5728> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/PTEN> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A8I5KSF9> , <https://identifiers.org/uniprot/A0A087X033> , <https://identifiers.org/uniprot/A0A8V8TP77> , <https://identifiers.org/uniprot/A0A8V8TQX2> , <https://identifiers.org/uniprot/P60484> , <https://identifiers.org/uniprot/F6KD01> , <https://identifiers.org/uniprot/A0A8V8TPK6> , <https://identifiers.org/uniprot/A0A8I5KVQ8> , <https://identifiers.org/uniprot/A0A8I5KR36> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/a3aed> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A8V8TPK6> , <http://purl.uniprot.org/uniprot/A0A8I5KR36> , <http://purl.uniprot.org/uniprot/A0A8V8TP77> , <http://purl.uniprot.org/uniprot/F6KD01> , <http://purl.uniprot.org/uniprot/A0A8V8TQX2> , <http://purl.uniprot.org/uniprot/P60484> , <http://purl.uniprot.org/uniprot/A0A8I5KSF9> , <http://purl.uniprot.org/uniprot/A0A087X033> , <http://purl.uniprot.org/uniprot/A0A8I5KVQ8> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000171862> .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/ComplexBinding/baa75>
        rdf:type          wp:ComplexBinding , wp:Binding , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4674_r142545> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Group/baa75> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000145675> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Complex/baa75> , <https://identifiers.org/ensembl/ENSG00000105647> , <https://identifiers.org/ensembl/ENSG00000121879> , <https://identifiers.org/ensembl/ENSG00000051382> .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/ComplexBinding/d6359>
        rdf:type          wp:ComplexBinding , wp:Binding , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4674_r142545> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Group/d6359> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000105810> , <https://identifiers.org/ensembl/ENSG00000135446> , <https://identifiers.org/ensembl/ENSG00000124762> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Complex/d6359> .

<https://identifiers.org/ensembl/ENSG00000110330>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "BIRC2" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000110330> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000110330" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4674_r142545/WP/Interaction/id19ff6cd6> , <http://rdf.wikipathways.org/Pathway/WP4674_r142545/WP/Interaction/id17ef750> , <https://identifiers.org/wikipathways/WP4674_r142545> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000110330> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/329> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/BIRC2> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/E9PIW1> , <https://identifiers.org/uniprot/Q13490> , <https://identifiers.org/uniprot/E9PQZ9> , <https://identifiers.org/uniprot/E9PI77> , <https://identifiers.org/uniprot/H0YDY3> , <https://identifiers.org/uniprot/E9PNM6> , <https://identifiers.org/uniprot/E9PMH5> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q17830271> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4674_r142545/DataNode/cf704> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/E9PMH5> , <http://purl.uniprot.org/uniprot/H0YDY3> , <http://purl.uniprot.org/uniprot/E9PNM6> , <http://purl.uniprot.org/uniprot/Q13490> , <http://purl.uniprot.org/uniprot/E9PQZ9> , <http://purl.uniprot.org/uniprot/E9PI77> , <http://purl.uniprot.org/uniprot/E9PIW1> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000110330> .

<http://rdf.wikipathways.org/Pathway/WP4674_r142545/WP/Interaction/id5178da0d>
        rdf:type          wp:Inhibition , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4674_r142545> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4674_r142545/Interaction/id5178da0d> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000168036> , <https://identifiers.org/ensembl/ENSG00000134250> ;
        wp:source         <https://identifiers.org/ensembl/ENSG00000134250> ;
        wp:target         <https://identifiers.org/ensembl/ENSG00000168036> .
