@prefix biopax:  <http://www.biopax.org/release/biopax-level3.owl#> .
@prefix cito:    <http://purl.org/spar/cito/> .
@prefix dc:      <http://purl.org/dc/elements/1.1/> .
@prefix dcterms: <http://purl.org/dc/terms/> .
@prefix foaf:    <http://xmlns.com/foaf/0.1/> .
@prefix freq:    <http://purl.org/cld/freq/> .
@prefix gpml:    <http://vocabularies.wikipathways.org/gpml#> .
@prefix obo:     <http://purl.obolibrary.org/obo/> .
@prefix owl:     <http://www.w3.org/2002/07/owl#> .
@prefix pav:     <http://purl.org/pav/> .
@prefix prov:    <http://www.w3.org/ns/prov#> .
@prefix rdf:     <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix rdfs:    <http://www.w3.org/2000/01/rdf-schema#> .
@prefix skos:    <http://www.w3.org/2004/02/skos/core#> .
@prefix void:    <http://rdfs.org/ns/void#> .
@prefix wp:      <http://vocabularies.wikipathways.org/wp#> .
@prefix wprdf:   <http://rdf.wikipathways.org/> .
@prefix xsd:     <http://www.w3.org/2001/XMLSchema#> .

<https://identifiers.org/ensembl/FBgn0039713>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "RpS8" ;
        dc:identifier       <https://identifiers.org/ensembl/FBgn0039713> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "FBgn0039713" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP3653_r129700> , <http://rdf.wikipathways.org/Pathway/WP3653_r129700/WP/Interaction/id5c21b72a> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/FBgn0039713> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/43532> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q8MLY8> , <https://identifiers.org/uniprot/A0A0B4K6N1> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q29722997> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP3653_r129700/DataNode/b6a8d> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A0B4K6N1> , <http://purl.uniprot.org/uniprot/Q8MLY8> ;
        foaf:page           <https://www.ensembl.org/id/FBgn0039713> .

<http://rdf.wikipathways.org/Pathway/WP3653_r129700/WP/Interaction/id7c584170>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP3653_r129700> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP3653_r129700/Interaction/id7c584170> ;
        wp:participants   <https://identifiers.org/ensembl/FBgn0032006> , <https://identifiers.org/ensembl/FBgn0039120> ;
        wp:source         <https://identifiers.org/ensembl/FBgn0039120> ;
        wp:target         <https://identifiers.org/ensembl/FBgn0032006> .

<https://identifiers.org/ensembl/FBgn0039120>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "Nup98-96" ;
        dc:identifier       <https://identifiers.org/ensembl/FBgn0039120> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "FBgn0039120" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP3653_r129700> , <http://rdf.wikipathways.org/Pathway/WP3653_r129700/WP/Interaction/id7682e514> , <http://rdf.wikipathways.org/Pathway/WP3653_r129700/WP/Interaction/id7c584170> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/FBgn0039120> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/42816> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A1YK33> , <https://identifiers.org/uniprot/Q867H5> , <https://identifiers.org/uniprot/Q867W7> , <https://identifiers.org/uniprot/A1YK24> , <https://identifiers.org/uniprot/A1YK25> , <https://identifiers.org/uniprot/Q868A8> , <https://identifiers.org/uniprot/B8A421> , <https://identifiers.org/uniprot/A1YK38> , <https://identifiers.org/uniprot/Q9VCH5> , <https://identifiers.org/uniprot/A1YK27> , <https://identifiers.org/uniprot/A1YK35> , <https://identifiers.org/uniprot/Q867M2> , <https://identifiers.org/uniprot/Q86G43> , <https://identifiers.org/uniprot/Q867M7> , <https://identifiers.org/uniprot/A1YK36> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q29717024> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP3653_r129700/DataNode/c9948> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A1YK38> , <http://purl.uniprot.org/uniprot/Q867M7> , <http://purl.uniprot.org/uniprot/A1YK27> , <http://purl.uniprot.org/uniprot/Q86G43> , <http://purl.uniprot.org/uniprot/Q867W7> , <http://purl.uniprot.org/uniprot/Q867M2> , <http://purl.uniprot.org/uniprot/Q868A8> , <http://purl.uniprot.org/uniprot/A1YK36> , <http://purl.uniprot.org/uniprot/A1YK25> , <http://purl.uniprot.org/uniprot/Q9VCH5> , <http://purl.uniprot.org/uniprot/A1YK35> , <http://purl.uniprot.org/uniprot/Q867H5> , <http://purl.uniprot.org/uniprot/A1YK33> , <http://purl.uniprot.org/uniprot/B8A421> , <http://purl.uniprot.org/uniprot/A1YK24> ;
        foaf:page           <https://www.ensembl.org/id/FBgn0039120> .

<http://rdf.wikipathways.org/Pathway/WP3653_r129700/WP/Interaction/id7682e514>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP3653_r129700> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP3653_r129700/Interaction/id7682e514> ;
        wp:participants   <https://identifiers.org/ensembl/FBgn0026263> , <https://identifiers.org/ensembl/FBgn0039120> ;
        wp:source         <https://identifiers.org/ensembl/FBgn0039120> ;
        wp:target         <https://identifiers.org/ensembl/FBgn0026263> .

<http://rdf.wikipathways.org/Pathway/WP3653_r129700/WP/Interaction/idb849e7c3>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP3653_r129700> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP3653_r129700/Interaction/idb849e7c3> ;
        wp:participants   <https://identifiers.org/ensembl/FBgn0032006> , <https://identifiers.org/ensembl/FBgn0026263> ;
        wp:source         <https://identifiers.org/ensembl/FBgn0026263> ;
        wp:target         <https://identifiers.org/ensembl/FBgn0032006> .

<https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=svg&pwTitle=Pathway:WP3653&oldid=129700>
        rdf:type        foaf:Image ;
        dcterms:format  "image/svg+xml" .

<https://identifiers.org/wikipathways/WP3653_r129700>
        rdf:type               wp:Pathway , skos:Collection ;
        dc:identifier          <https://identifiers.org/wikipathways/WP3653> ;
        dc:source              "WikiPathways" ;
        dc:title               "Equilibrium signaling of differentiated cells"@en ;
        dcterms:description    "Equilibrium signalling pathway for maintenance of progenitor cells in the lymph gland which is also affected by hedgehog protein niche signaling. Nup98 and Bip1 proteins both necessary for Pvr gene expression. Pvr/STAT92E complex activates Adgf-A to break down adenosine. Break down allows for proper maintenance of progenitor cells in equilibrium signalling. Niche signalling includes the expression of hedgehog by posterior signaling center also promoting progenitor maintenance. This pathway is based on figure 7 from Mondal et al." ;
        dcterms:identifier     "WP3653" ;
        dcterms:references     <https://identifiers.org/pubmed/25201876> ;
        cito:cites             <https://identifiers.org/pubmed/25201876> ;
        wp:isAbout             <http://rdf.wikipathways.org/Pathway/WP3653_r129700> ;
        wp:ontologyTag         wp:Curation:AnalysisCollection , obo:PW_0000003 , obo:PW_0000004 ;
        wp:organism            obo:NCBITaxon_7227 ;
        wp:organismName        "Drosophila melanogaster" ;
        wp:pathwayOntologyTag  obo:PW_0000004 , obo:PW_0000003 ;
        foaf:img               <https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=png&pwTitle=Pathway:WP3653&oldid=129700> , <https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=svg&pwTitle=Pathway:WP3653&oldid=129700> ;
        foaf:page              <http://www.wikipathways.org/instance/WP3653_r129700> .

<http://rdf.wikipathways.org/Pathway/WP3653_r129700/WP/Interaction/id21913b78>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP3653_r129700> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP3653_r129700/Interaction/id21913b78> ;
        wp:participants   <https://identifiers.org/ensembl/FBgn0036752> , <https://identifiers.org/ensembl/FBgn0016917> ;
        wp:source         <https://identifiers.org/ensembl/FBgn0016917> ;
        wp:target         <https://identifiers.org/ensembl/FBgn0036752> .

<http://rdf.wikipathways.org/Pathway/WP3653_r129700/WP/Interaction/id5c21b72a>
        rdf:type          wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP3653_r129700> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP3653_r129700/Interaction/id5c21b72a> ;
        wp:participants   <https://identifiers.org/ensembl/FBgn0039713> , <https://identifiers.org/ensembl/FBgn0026263> .

<https://identifiers.org/wikipathways/WP3653>
        pav:hasVersion  <https://identifiers.org/wikipathways/WP3653_r129700> .

obo:NCBITaxon_7227  obo:NCIT_C179773  "7227" .

<https://identifiers.org/ensembl/FBgn0026263>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "bip1" ;
        dc:identifier       <https://identifiers.org/ensembl/FBgn0026263> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "FBgn0026263" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP3653_r129700/WP/Interaction/idb849e7c3> , <https://identifiers.org/wikipathways/WP3653_r129700> , <http://rdf.wikipathways.org/Pathway/WP3653_r129700/WP/Interaction/id7682e514> , <http://rdf.wikipathways.org/Pathway/WP3653_r129700/WP/Interaction/id5c21b72a> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/FBgn0026263> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/38891> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q9XZU6> , <https://identifiers.org/uniprot/Q9V457> , <https://identifiers.org/uniprot/C6SV53> , <https://identifiers.org/uniprot/Q8T9I2> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q29722286> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP3653_r129700/DataNode/c8369> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q8T9I2> , <http://purl.uniprot.org/uniprot/Q9V457> , <http://purl.uniprot.org/uniprot/C6SV53> , <http://purl.uniprot.org/uniprot/Q9XZU6> ;
        foaf:page           <https://www.ensembl.org/id/FBgn0026263> .

<https://identifiers.org/ensembl/FBgn0016917>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "Stat92E" ;
        dc:identifier       <https://identifiers.org/ensembl/FBgn0016917> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "FBgn0016917" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP3653_r129700> , <http://rdf.wikipathways.org/Pathway/WP3653_r129700/WP/Interaction/id21913b78> , <http://rdf.wikipathways.org/Pathway/WP3653_r129700/WP/Interaction/id2989e728> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/FBgn0016917> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/42428> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A0B4KHS6> , <https://identifiers.org/uniprot/Q24151> , <https://identifiers.org/uniprot/A0A0B4KGE1> , <https://identifiers.org/uniprot/A0A0B4KHS7> , <https://identifiers.org/uniprot/A0A0B4KGI7> , <https://identifiers.org/uniprot/A0A0B4KH10> , <https://identifiers.org/uniprot/D2NUE7> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q29733741> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP3653_r129700/DataNode/fe9b3> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q24151> , <http://purl.uniprot.org/uniprot/A0A0B4KGE1> , <http://purl.uniprot.org/uniprot/A0A0B4KH10> , <http://purl.uniprot.org/uniprot/D2NUE7> , <http://purl.uniprot.org/uniprot/A0A0B4KHS6> , <http://purl.uniprot.org/uniprot/A0A0B4KGI7> , <http://purl.uniprot.org/uniprot/A0A0B4KHS7> ;
        foaf:page           <https://www.ensembl.org/id/FBgn0016917> .

<https://identifiers.org/ensembl/FBgn0036752>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "Adgf-A" ;
        dc:identifier       <https://identifiers.org/ensembl/FBgn0036752> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "FBgn0036752" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP3653_r129700> , <http://rdf.wikipathways.org/Pathway/WP3653_r129700/WP/Interaction/id21913b78> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/FBgn0036752> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/39976> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q9VVK5> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q29733431> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP3653_r129700/DataNode/f7d4a> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q9VVK5> ;
        foaf:page           <https://www.ensembl.org/id/FBgn0036752> .

<https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=png&pwTitle=Pathway:WP3653&oldid=129700>
        rdf:type        foaf:Image ;
        dcterms:format  "image/png" .

<https://identifiers.org/ensembl/FBgn0032006>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "Pvr" ;
        dc:identifier       <https://identifiers.org/ensembl/FBgn0032006> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "FBgn0032006" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP3653_r129700/WP/Interaction/idb849e7c3> , <http://rdf.wikipathways.org/Pathway/WP3653_r129700/WP/Interaction/id7c584170> , <http://rdf.wikipathways.org/Pathway/WP3653_r129700/WP/Interaction/id2989e728> , <https://identifiers.org/wikipathways/WP3653_r129700> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/FBgn0032006> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/34127> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q8T4L8> , <https://identifiers.org/uniprot/Q8IPG1> , <https://identifiers.org/uniprot/B6IDV6> , <https://identifiers.org/uniprot/Q8T4M0> , <https://identifiers.org/uniprot/Q7KTI8> , <https://identifiers.org/uniprot/C1C3C7> , <https://identifiers.org/uniprot/M9PCX2> , <https://identifiers.org/uniprot/E1JHB6> , <https://identifiers.org/uniprot/E1JHB8> , <https://identifiers.org/uniprot/Q7KTI7> , <https://identifiers.org/uniprot/M9MRE1> , <https://identifiers.org/uniprot/C4IXZ5> , <https://identifiers.org/uniprot/Q8T4L9> , <https://identifiers.org/uniprot/Q1LZ47> , <https://identifiers.org/uniprot/E1JHB7> , <https://identifiers.org/uniprot/Q95P10> , <https://identifiers.org/uniprot/Q9VLQ8> , <https://identifiers.org/uniprot/Q8T9F6> , <https://identifiers.org/uniprot/M9PCJ1> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q29719607> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP3653_r129700/DataNode/d77f0> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q8IPG1> , <http://purl.uniprot.org/uniprot/Q95P10> , <http://purl.uniprot.org/uniprot/E1JHB8> , <http://purl.uniprot.org/uniprot/E1JHB7> , <http://purl.uniprot.org/uniprot/Q7KTI8> , <http://purl.uniprot.org/uniprot/Q7KTI7> , <http://purl.uniprot.org/uniprot/M9PCJ1> , <http://purl.uniprot.org/uniprot/E1JHB6> , <http://purl.uniprot.org/uniprot/B6IDV6> , <http://purl.uniprot.org/uniprot/M9MRE1> , <http://purl.uniprot.org/uniprot/Q9VLQ8> , <http://purl.uniprot.org/uniprot/C4IXZ5> , <http://purl.uniprot.org/uniprot/M9PCX2> , <http://purl.uniprot.org/uniprot/Q8T9F6> , <http://purl.uniprot.org/uniprot/Q8T4M0> , <http://purl.uniprot.org/uniprot/C1C3C7> , <http://purl.uniprot.org/uniprot/Q8T4L8> , <http://purl.uniprot.org/uniprot/Q8T4L9> , <http://purl.uniprot.org/uniprot/Q1LZ47> ;
        foaf:page           <https://www.ensembl.org/id/FBgn0032006> .

<http://rdf.wikipathways.org/Pathway/WP3653_r129700/WP/Interaction/id2989e728>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP3653_r129700> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP3653_r129700/Interaction/id2989e728> ;
        wp:participants   <https://identifiers.org/ensembl/FBgn0016917> , <https://identifiers.org/ensembl/FBgn0032006> ;
        wp:source         <https://identifiers.org/ensembl/FBgn0032006> ;
        wp:target         <https://identifiers.org/ensembl/FBgn0016917> .

<https://identifiers.org/uniprot/Q02936>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "Hedgehog" ;
        dc:identifier       <https://identifiers.org/uniprot/Q02936> ;
        dc:source           "UniProtKB" ;
        dcterms:identifier  "Q02936" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP3653_r129700> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/FBgn0004644> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/42737> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q02936> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP3653_r129700/DataNode/e06e8> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q02936> ;
        foaf:page           <http://www.uniprot.org/uniprot/Q02936> .

<https://identifiers.org/pubmed/25201876>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "25201876" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP3653_r129700> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/25201876> .
