@prefix biopax:  <http://www.biopax.org/release/biopax-level3.owl#> .
@prefix cito:    <http://purl.org/spar/cito/> .
@prefix dc:      <http://purl.org/dc/elements/1.1/> .
@prefix dcterms: <http://purl.org/dc/terms/> .
@prefix foaf:    <http://xmlns.com/foaf/0.1/> .
@prefix freq:    <http://purl.org/cld/freq/> .
@prefix gpml:    <http://vocabularies.wikipathways.org/gpml#> .
@prefix obo:     <http://purl.obolibrary.org/obo/> .
@prefix owl:     <http://www.w3.org/2002/07/owl#> .
@prefix pav:     <http://purl.org/pav/> .
@prefix prov:    <http://www.w3.org/ns/prov#> .
@prefix rdf:     <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix rdfs:    <http://www.w3.org/2000/01/rdf-schema#> .
@prefix skos:    <http://www.w3.org/2004/02/skos/core#> .
@prefix void:    <http://rdfs.org/ns/void#> .
@prefix wp:      <http://vocabularies.wikipathways.org/wp#> .
@prefix wprdf:   <http://rdf.wikipathways.org/> .
@prefix xsd:     <http://www.w3.org/2001/XMLSchema#> .

<http://rdf.wikipathways.org/Pathway/WP2813_r137944/WP/Interaction/id8a530b78>
        rdf:type            wp:Inhibition , wp:Interaction , wp:DirectedInteraction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2813_r137944> ;
        dcterms:references  <https://identifiers.org/pubmed/19424592> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2813_r137944/Interaction/id8a530b78> ;
        wp:participants     <https://identifiers.org/ensembl/ENSG00000169554> , <https://identifiers.org/ensembl/ENSG00000104332> ;
        wp:source           <https://identifiers.org/ensembl/ENSG00000169554> ;
        wp:target           <https://identifiers.org/ensembl/ENSG00000104332> .

<https://identifiers.org/ensembl/ENSG00000136997>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "MYC" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000136997> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000136997" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2813_r137944/WP/Interaction/id2ab32d01> , <https://identifiers.org/wikipathways/WP2813_r137944> , <http://rdf.wikipathways.org/Pathway/WP2813_r137944/WP/Interaction/idfb1f312f> , <http://rdf.wikipathways.org/Pathway/WP2813_r137944/WP/Interaction/id5b89ae88> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000136997> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/4609> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/MYC> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q16591> , <https://identifiers.org/uniprot/P01106> , <https://identifiers.org/uniprot/A0A0B4J1R1> , <https://identifiers.org/uniprot/H0YBG3> , <https://identifiers.org/uniprot/A0A494C1T8> , <https://identifiers.org/uniprot/Q14899> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q20969939> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2813_r137944/DataNode/b9ff0> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A494C1T8> , <http://purl.uniprot.org/uniprot/H0YBG3> , <http://purl.uniprot.org/uniprot/Q16591> , <http://purl.uniprot.org/uniprot/Q14899> , <http://purl.uniprot.org/uniprot/A0A0B4J1R1> , <http://purl.uniprot.org/uniprot/P01106> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000136997> .

<https://identifiers.org/wikipathways/WP2817>
        rdf:type            wp:Pathway , wp:DataNode ;
        rdfs:label          "Pregnancy and lactation" ;
        dc:identifier       <https://identifiers.org/wikipathways/WP2817> ;
        dc:source           "WikiPathways" ;
        dcterms:identifier  "WP2817" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2813_r137944> , <http://rdf.wikipathways.org/Pathway/WP2813_r137944/WP/Interaction/id18d6867f> , <http://rdf.wikipathways.org/Pathway/WP2813_r137944/WP/Interaction/id3ef4167f> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2813_r137944/DataNode/f2370> ;
        foaf:page           <https://www.wikipathways.org/instance/WP2817> .

<http://rdf.wikipathways.org/Pathway/WP2813_r137944/WP/Interaction/id45a0e36b>
        rdf:type            wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2813_r137944> ;
        dcterms:references  <https://identifiers.org/pubmed/17880691> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2813_r137944/Interaction/id45a0e36b> ;
        wp:participants     <https://identifiers.org/ensembl/ENSG00000178568> , <https://identifiers.org/ensembl/ENSG00000185737> ;
        wp:source           <https://identifiers.org/ensembl/ENSG00000185737> ;
        wp:target           <https://identifiers.org/ensembl/ENSG00000178568> .

<https://identifiers.org/ensembl/ENSG00000104332>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "SFRP1" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000104332> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000104332" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2813_r137944/WP/Interaction/id8a530b78> , <https://identifiers.org/wikipathways/WP2813_r137944> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000104332> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/6422> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/SFRP1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q6ZSL4> , <https://identifiers.org/uniprot/Q8N474> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18031450> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2813_r137944/DataNode/be06c> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q8N474> , <http://purl.uniprot.org/uniprot/Q6ZSL4> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000104332> .

<https://identifiers.org/ensembl/ENSG00000185737>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "NRG3" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000185737> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000185737" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2813_r137944/WP/Interaction/id45a0e36b> , <https://identifiers.org/wikipathways/WP2813_r137944> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000185737> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/10718> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/NRG3> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/D9ZHQ3> , <https://identifiers.org/uniprot/D9ZHQ6> , <https://identifiers.org/uniprot/D9ZHP6> , <https://identifiers.org/uniprot/R4GNI6> , <https://identifiers.org/uniprot/D9ZHQ7> , <https://identifiers.org/uniprot/D9ZHQ8> , <https://identifiers.org/uniprot/P56975> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18035621> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2813_r137944/DataNode/e9314> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/D9ZHQ8> , <http://purl.uniprot.org/uniprot/R4GNI6> , <http://purl.uniprot.org/uniprot/D9ZHP6> , <http://purl.uniprot.org/uniprot/D9ZHQ7> , <http://purl.uniprot.org/uniprot/D9ZHQ6> , <http://purl.uniprot.org/uniprot/D9ZHQ3> , <http://purl.uniprot.org/uniprot/P56975> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000185737> .

<https://identifiers.org/ensembl/ENSG00000189143>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "CLDN4" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000189143> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000189143" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2813_r137944/WP/Interaction/id2f2e0ed5> , <https://identifiers.org/wikipathways/WP2813_r137944> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000189143> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/1364> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/CLDN4> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/O14493> , <https://identifiers.org/uniprot/Q75L80> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q17909139> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2813_r137944/DataNode/c4e34> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q75L80> , <http://purl.uniprot.org/uniprot/O14493> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000189143> .

<https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=svg&pwTitle=Pathway:WP2813&oldid=137944>
        rdf:type        foaf:Image ;
        dcterms:format  "image/svg+xml" .

<http://rdf.wikipathways.org/Pathway/WP2813_r137944/WP/Interaction/ide8178db0>
        rdf:type            wp:Inhibition , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2813_r137944> ;
        dcterms:references  <https://identifiers.org/pubmed/19424592> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2813_r137944/Interaction/ide8178db0> ;
        wp:participants     <https://identifiers.org/ensembl/ENSG00000169554> , <https://identifiers.org/ensembl/ENSG00000164362> ;
        wp:source           <https://identifiers.org/ensembl/ENSG00000169554> ;
        wp:target           <https://identifiers.org/ensembl/ENSG00000164362> .

<https://identifiers.org/ensembl/ENSG00000207730>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "MIR200B" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000207730> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000207730" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2813_r137944> , <http://rdf.wikipathways.org/Pathway/WP2813_r137944/WP/Interaction/id7bde5174> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000207730> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/406984> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/MIR200B> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18058109> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2813_r137944/DataNode/a53a8> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000207730> .

<https://identifiers.org/ensembl/ENSG00000169554>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "ZEB2" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000169554> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000169554" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2813_r137944/WP/Interaction/id1aac8138> , <http://rdf.wikipathways.org/Pathway/WP2813_r137944/WP/Interaction/ida3e58876> , <http://rdf.wikipathways.org/Pathway/WP2813_r137944/WP/Interaction/id24c31193> , <http://rdf.wikipathways.org/Pathway/WP2813_r137944/WP/Interaction/idb966722> , <http://rdf.wikipathways.org/Pathway/WP2813_r137944/WP/Interaction/id2f2e0ed5> , <http://rdf.wikipathways.org/Pathway/WP2813_r137944/WP/Interaction/ide93edc51> , <https://identifiers.org/wikipathways/WP2813_r137944> , <http://rdf.wikipathways.org/Pathway/WP2813_r137944/WP/Interaction/id5dd91c8e> , <http://rdf.wikipathways.org/Pathway/WP2813_r137944/WP/Interaction/ide8178db0> , <http://rdf.wikipathways.org/Pathway/WP2813_r137944/WP/Interaction/idadeab32b> , <http://rdf.wikipathways.org/Pathway/WP2813_r137944/WP/Interaction/idb7af60b8> , <http://rdf.wikipathways.org/Pathway/WP2813_r137944/WP/Interaction/id7bde5174> , <http://rdf.wikipathways.org/Pathway/WP2813_r137944/WP/Interaction/id8a530b78> , <http://rdf.wikipathways.org/Pathway/WP2813_r137944/WP/Interaction/id896466d2> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000169554> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/9839> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/ZEB2> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A6Q8PH34> , <https://identifiers.org/uniprot/A0A1B0GUM8> , <https://identifiers.org/uniprot/U3KQ51> , <https://identifiers.org/uniprot/E7EVG9> , <https://identifiers.org/uniprot/U3KPV5> , <https://identifiers.org/uniprot/A0A1B0GVV8> , <https://identifiers.org/uniprot/A0A1B0GV02> , <https://identifiers.org/uniprot/A0A1B0GTH3> , <https://identifiers.org/uniprot/C9JU62> , <https://identifiers.org/uniprot/A0A1X7SC99> , <https://identifiers.org/uniprot/A0A1W2PS25> , <https://identifiers.org/uniprot/A0A0D9SF71> , <https://identifiers.org/uniprot/U3KQ33> , <https://identifiers.org/uniprot/H7C0G0> , <https://identifiers.org/uniprot/A0A2R8YDQ8> , <https://identifiers.org/uniprot/O60315> , <https://identifiers.org/uniprot/A0A1B0GWA7> , <https://identifiers.org/uniprot/A0A0D9SGG5> , <https://identifiers.org/uniprot/E7ESP8> , <https://identifiers.org/uniprot/A0A0D9SF74> , <https://identifiers.org/uniprot/A0A8I5KV18> , <https://identifiers.org/uniprot/E7EUW9> , <https://identifiers.org/uniprot/A0A1B0GW50> , <https://identifiers.org/uniprot/A0JP08> , <https://identifiers.org/uniprot/C9JUQ1> , <https://identifiers.org/uniprot/U3KPX6> , <https://identifiers.org/uniprot/A0A0D9SG93> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q15318481> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2813_r137944/DataNode/c2c71> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/E7ESP8> , <http://purl.uniprot.org/uniprot/A0A1B0GVV8> , <http://purl.uniprot.org/uniprot/A0JP08> , <http://purl.uniprot.org/uniprot/U3KPX6> , <http://purl.uniprot.org/uniprot/C9JU62> , <http://purl.uniprot.org/uniprot/E7EUW9> , <http://purl.uniprot.org/uniprot/A0A6Q8PH34> , <http://purl.uniprot.org/uniprot/A0A1B0GTH3> , <http://purl.uniprot.org/uniprot/A0A0D9SF71> , <http://purl.uniprot.org/uniprot/A0A0D9SG93> , <http://purl.uniprot.org/uniprot/A0A1B0GWA7> , <http://purl.uniprot.org/uniprot/A0A1X7SC99> , <http://purl.uniprot.org/uniprot/A0A1B0GW50> , <http://purl.uniprot.org/uniprot/H7C0G0> , <http://purl.uniprot.org/uniprot/A0A8I5KV18> , <http://purl.uniprot.org/uniprot/A0A0D9SF74> , <http://purl.uniprot.org/uniprot/A0A1B0GUM8> , <http://purl.uniprot.org/uniprot/C9JUQ1> , <http://purl.uniprot.org/uniprot/A0A1B0GV02> , <http://purl.uniprot.org/uniprot/U3KQ33> , <http://purl.uniprot.org/uniprot/O60315> , <http://purl.uniprot.org/uniprot/A0A0D9SGG5> , <http://purl.uniprot.org/uniprot/A0A1W2PS25> , <http://purl.uniprot.org/uniprot/A0A2R8YDQ8> , <http://purl.uniprot.org/uniprot/E7EVG9> , <http://purl.uniprot.org/uniprot/U3KQ51> , <http://purl.uniprot.org/uniprot/U3KPV5> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000169554> .

<https://identifiers.org/ensembl/ENSG00000105329>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "TGFB1" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000105329> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000105329" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2813_r137944> , <http://rdf.wikipathways.org/Pathway/WP2813_r137944/WP/Interaction/ide93edc51> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000105329> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/7040> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/TGFB1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A7I2V5Z9> , <https://identifiers.org/uniprot/A0A7I2YQL8> , <https://identifiers.org/uniprot/A0A499FJK2> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q14904613> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2813_r137944/DataNode/e4149> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A499FJK2> , <http://purl.uniprot.org/uniprot/A0A7I2YQL8> , <http://purl.uniprot.org/uniprot/A0A7I2V5Z9> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000105329> .

<https://identifiers.org/ensembl/ENSG00000178568>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "ERBB4" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000178568> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000178568" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2813_r137944/WP/Interaction/idfb1f312f> , <http://rdf.wikipathways.org/Pathway/WP2813_r137944/WP/Interaction/id45a0e36b> , <https://identifiers.org/wikipathways/WP2813_r137944> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000178568> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/2066> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/ERBB4> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q15303> , <https://identifiers.org/uniprot/H3BLT0> , <https://identifiers.org/uniprot/E9PDR1> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q17917202> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2813_r137944/DataNode/de529> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/H3BLT0> , <http://purl.uniprot.org/uniprot/Q15303> , <http://purl.uniprot.org/uniprot/E9PDR1> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000178568> .

<http://rdf.wikipathways.org/Pathway/WP2813_r137944/WP/Interaction/idfb1f312f>
        rdf:type            wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2813_r137944> ;
        dcterms:references  <https://identifiers.org/pubmed/17880691> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2813_r137944/Interaction/idfb1f312f> ;
        wp:participants     <https://identifiers.org/ensembl/ENSG00000136997> , <https://identifiers.org/ensembl/ENSG00000178568> ;
        wp:source           <https://identifiers.org/ensembl/ENSG00000178568> ;
        wp:target           <https://identifiers.org/ensembl/ENSG00000136997> .

<http://rdf.wikipathways.org/Pathway/WP2813_r137944/WP/Interaction/id2ab32d01>
        rdf:type            wp:Inhibition , wp:Interaction , wp:DirectedInteraction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2813_r137944> ;
        dcterms:references  <https://identifiers.org/pubmed/17880691> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2813_r137944/Interaction/id2ab32d01> ;
        wp:participants     <https://identifiers.org/ensembl/ENSG00000136997> , <https://identifiers.org/ensembl/ENSG00000091409> ;
        wp:source           <https://identifiers.org/ensembl/ENSG00000136997> ;
        wp:target           <https://identifiers.org/ensembl/ENSG00000091409> .

<https://identifiers.org/ensembl/ENSG00000039068>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "CDH1" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000039068> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000039068" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2813_r137944/WP/Interaction/id24c31193> , <https://identifiers.org/wikipathways/WP2813_r137944> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000039068> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/999> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/CDH1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/H3BNC6> , <https://identifiers.org/uniprot/H3BVI7> , <https://identifiers.org/uniprot/P12830> , <https://identifiers.org/uniprot/J3QKP1> , <https://identifiers.org/uniprot/A0A0U2ZQU7> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q17859787> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2813_r137944/DataNode/fbcd7> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P12830> , <http://purl.uniprot.org/uniprot/H3BNC6> , <http://purl.uniprot.org/uniprot/A0A0U2ZQU7> , <http://purl.uniprot.org/uniprot/J3QKP1> , <http://purl.uniprot.org/uniprot/H3BVI7> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000039068> .

<http://rdf.wikipathways.org/Pathway/WP2813_r137944/WP/Interaction/ida3e58876>
        rdf:type            wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2813_r137944> ;
        dcterms:references  <https://identifiers.org/pubmed/19424592> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2813_r137944/Interaction/ida3e58876> ;
        wp:participants     <https://identifiers.org/ensembl/ENSG00000169554> , <https://identifiers.org/interpro/IPR000975> ;
        wp:source           <https://identifiers.org/interpro/IPR000975> ;
        wp:target           <https://identifiers.org/ensembl/ENSG00000169554> .

<http://rdf.wikipathways.org/Pathway/WP2813_r137944/WP/Interaction/id896466d2>
        rdf:type            wp:Inhibition , wp:Interaction , wp:DirectedInteraction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2813_r137944> ;
        dcterms:references  <https://identifiers.org/pubmed/19424592> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2813_r137944/Interaction/id896466d2> ;
        wp:participants     <https://identifiers.org/ensembl/ENSG00000169554> , <https://identifiers.org/ensembl/ENSG00000207607> ;
        wp:source           <https://identifiers.org/ensembl/ENSG00000169554> ;
        wp:target           <https://identifiers.org/ensembl/ENSG00000207607> .

<http://rdf.wikipathways.org/Pathway/WP2813_r137944/WP/Interaction/id2f2e0ed5>
        rdf:type            wp:Inhibition , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2813_r137944> ;
        dcterms:references  <https://identifiers.org/pubmed/19424592> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2813_r137944/Interaction/id2f2e0ed5> ;
        wp:participants     <https://identifiers.org/ensembl/ENSG00000189143> , <https://identifiers.org/ensembl/ENSG00000169554> ;
        wp:source           <https://identifiers.org/ensembl/ENSG00000169554> ;
        wp:target           <https://identifiers.org/ensembl/ENSG00000189143> .

<https://identifiers.org/ensembl/ENSG00000232810>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "TNF" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000232810> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000232810" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2813_r137944> , <http://rdf.wikipathways.org/Pathway/WP2813_r137944/WP/Interaction/id5dd91c8e> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000232810> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/7124> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/TNF> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q5STB3> , <https://identifiers.org/uniprot/A0A8V8TNL2> , <https://identifiers.org/uniprot/P01375> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18032037> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2813_r137944/DataNode/fe7da> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P01375> , <http://purl.uniprot.org/uniprot/Q5STB3> , <http://purl.uniprot.org/uniprot/A0A8V8TNL2> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000232810> .

<https://identifiers.org/ensembl/ENSG00000207607>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "MIR200A" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000207607> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000207607" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2813_r137944> , <http://rdf.wikipathways.org/Pathway/WP2813_r137944/WP/Interaction/id896466d2> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000207607> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/406983> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/MIR200A> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18058108> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2813_r137944/DataNode/ef5b1> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000207607> .

<https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=png&pwTitle=Pathway:WP2813&oldid=137944>
        rdf:type        foaf:Image ;
        dcterms:format  "image/png" .

<http://rdf.wikipathways.org/Pathway/WP2813_r137944/WP/Interaction/idb7af60b8>
        rdf:type            wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2813_r137944> ;
        dcterms:references  <https://identifiers.org/pubmed/19424592> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2813_r137944/Interaction/idb7af60b8> ;
        wp:participants     <https://identifiers.org/ensembl/ENSG00000169554> , <https://identifiers.org/ensembl/ENSG00000142208> ;
        wp:source           <https://identifiers.org/ensembl/ENSG00000142208> ;
        wp:target           <https://identifiers.org/ensembl/ENSG00000169554> .

<http://rdf.wikipathways.org/Pathway/WP2813_r137944/WP/Interaction/id24c31193>
        rdf:type            wp:DirectedInteraction , wp:Inhibition , wp:Interaction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2813_r137944> ;
        dcterms:references  <https://identifiers.org/pubmed/19424592> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2813_r137944/Interaction/id24c31193> ;
        wp:participants     <https://identifiers.org/ensembl/ENSG00000169554> , <https://identifiers.org/ensembl/ENSG00000039068> ;
        wp:source           <https://identifiers.org/ensembl/ENSG00000169554> ;
        wp:target           <https://identifiers.org/ensembl/ENSG00000039068> .

<https://identifiers.org/wikipathways/WP2815>
        rdf:type            wp:DataNode , wp:Pathway ;
        rdfs:label          "Involution" ;
        dc:identifier       <https://identifiers.org/wikipathways/WP2815> ;
        dc:source           "WikiPathways" ;
        dcterms:identifier  "WP2815" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2813_r137944/WP/Interaction/id3ef4167f> , <https://identifiers.org/wikipathways/WP2813_r137944> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2813_r137944/DataNode/b64ed> ;
        foaf:page           <https://www.wikipathways.org/instance/WP2815> .

obo:NCBITaxon_9606  obo:NCIT_C179773  "9606" .

<http://rdf.wikipathways.org/Pathway/WP2813_r137944/WP/Interaction/id5dd91c8e>
        rdf:type            wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2813_r137944> ;
        dcterms:references  <https://identifiers.org/pubmed/19424592> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2813_r137944/Interaction/id5dd91c8e> ;
        wp:participants     <https://identifiers.org/ensembl/ENSG00000169554> , <https://identifiers.org/ensembl/ENSG00000232810> ;
        wp:source           <https://identifiers.org/ensembl/ENSG00000232810> ;
        wp:target           <https://identifiers.org/ensembl/ENSG00000169554> .

<http://rdf.wikipathways.org/Pathway/WP2813_r137944/WP/Interaction/idb966722>
        rdf:type            wp:Interaction , wp:DirectedInteraction , wp:Inhibition ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2813_r137944> ;
        dcterms:references  <https://identifiers.org/pubmed/19424592> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2813_r137944/Interaction/idb966722> ;
        wp:participants     <https://identifiers.org/ensembl/ENSG00000169554> , <https://identifiers.org/ensembl/ENSG00000162551> ;
        wp:source           <https://identifiers.org/ensembl/ENSG00000169554> ;
        wp:target           <https://identifiers.org/ensembl/ENSG00000162551> .

<https://identifiers.org/ensembl/ENSG00000162551>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "ALPL" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000162551> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000162551" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2813_r137944> , <http://rdf.wikipathways.org/Pathway/WP2813_r137944/WP/Interaction/idb966722> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000162551> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/249> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/ALPL> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A024RAB4> , <https://identifiers.org/uniprot/P05186> , <https://identifiers.org/uniprot/B1ANL0> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q17825104> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2813_r137944/DataNode/c2a61> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P05186> , <http://purl.uniprot.org/uniprot/B1ANL0> , <http://purl.uniprot.org/uniprot/A0A024RAB4> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000162551> .

<https://identifiers.org/interpro/IPR000975>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "IL1" ;
        dc:identifier       <https://identifiers.org/interpro/IPR000975> ;
        dc:source           "InterPro" ;
        dcterms:identifier  "IPR000975" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2813_r137944/WP/Interaction/ida3e58876> , <https://identifiers.org/wikipathways/WP2813_r137944> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2813_r137944/DataNode/baf55> ;
        foaf:page           <https://www.ebi.ac.uk/interpro/entry/InterPro/IPR000975> .

<https://identifiers.org/pubmed/19424592>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "19424592" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2813_r137944/WP/Interaction/id2f2e0ed5> , <http://rdf.wikipathways.org/Pathway/WP2813_r137944/WP/Interaction/ida3e58876> , <http://rdf.wikipathways.org/Pathway/WP2813_r137944/WP/Interaction/id1aac8138> , <http://rdf.wikipathways.org/Pathway/WP2813_r137944/WP/Interaction/idb7af60b8> , <http://rdf.wikipathways.org/Pathway/WP2813_r137944/WP/Interaction/id24c31193> , <http://rdf.wikipathways.org/Pathway/WP2813_r137944/WP/Interaction/idb966722> , <http://rdf.wikipathways.org/Pathway/WP2813_r137944/WP/Interaction/ide8178db0> , <http://rdf.wikipathways.org/Pathway/WP2813_r137944/WP/Interaction/ide93edc51> , <http://rdf.wikipathways.org/Pathway/WP2813_r137944/WP/Interaction/id5dd91c8e> , <http://rdf.wikipathways.org/Pathway/WP2813_r137944/WP/Interaction/id7bde5174> , <http://rdf.wikipathways.org/Pathway/WP2813_r137944/WP/Interaction/idadeab32b> , <http://rdf.wikipathways.org/Pathway/WP2813_r137944/WP/Interaction/id8a530b78> , <http://rdf.wikipathways.org/Pathway/WP2813_r137944/WP/Interaction/id896466d2> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/19424592> .

<https://identifiers.org/ensembl/ENSG00000091409>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "ITGA6" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000091409> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000091409" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2813_r137944> , <http://rdf.wikipathways.org/Pathway/WP2813_r137944/WP/Interaction/id2ab32d01> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000091409> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/3655> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/ITGA6> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/C9JXX7> , <https://identifiers.org/uniprot/H7BZ97> , <https://identifiers.org/uniprot/A0A8C8KBL6> , <https://identifiers.org/uniprot/P23229> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18027984> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2813_r137944/DataNode/be934> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A8C8KBL6> , <http://purl.uniprot.org/uniprot/P23229> , <http://purl.uniprot.org/uniprot/C9JXX7> , <http://purl.uniprot.org/uniprot/H7BZ97> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000091409> .

<http://rdf.wikipathways.org/Pathway/WP2813_r137944/WP/Interaction/id3ef4167f>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2813_r137944> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2813_r137944/Interaction/id3ef4167f> ;
        wp:participants   <https://identifiers.org/wikipathways/WP2815> , <https://identifiers.org/wikipathways/WP2817> ;
        wp:source         <https://identifiers.org/wikipathways/WP2817> ;
        wp:target         <https://identifiers.org/wikipathways/WP2815> .

<http://rdf.wikipathways.org/Pathway/WP2813_r137944/WP/Interaction/id5b89ae88>
        rdf:type            wp:Interaction , wp:DirectedInteraction , wp:Inhibition ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2813_r137944> ;
        dcterms:references  <https://identifiers.org/pubmed/17880691> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2813_r137944/Interaction/id5b89ae88> ;
        wp:participants     <https://identifiers.org/ensembl/ENSG00000150093> , <https://identifiers.org/ensembl/ENSG00000136997> ;
        wp:source           <https://identifiers.org/ensembl/ENSG00000136997> ;
        wp:target           <https://identifiers.org/ensembl/ENSG00000150093> .

<https://identifiers.org/wikipathways/WP2814>
        rdf:type            wp:DataNode , wp:Pathway ;
        rdfs:label          "Puberty" ;
        dc:identifier       <https://identifiers.org/wikipathways/WP2814> ;
        dc:source           "WikiPathways" ;
        dcterms:identifier  "WP2814" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2813_r137944> , <http://rdf.wikipathways.org/Pathway/WP2813_r137944/WP/Interaction/id18d6867f> , <http://rdf.wikipathways.org/Pathway/WP2813_r137944/WP/Interaction/idf2b8f67f> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2813_r137944/DataNode/b1228> ;
        foaf:page           <https://www.wikipathways.org/instance/WP2814> .

<https://identifiers.org/ensembl/ENSG00000150093>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "ITGB1" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000150093> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000150093" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2813_r137944/WP/Interaction/id5b89ae88> , <https://identifiers.org/wikipathways/WP2813_r137944> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000150093> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/3688> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/ITGB1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q5T3E4> , <https://identifiers.org/uniprot/H7C4N8> , <https://identifiers.org/uniprot/A0A7I2V5T3> , <https://identifiers.org/uniprot/E9PLR6> , <https://identifiers.org/uniprot/A0A7I2V348> , <https://identifiers.org/uniprot/E7EQW5> , <https://identifiers.org/uniprot/A0A7I2V5Z8> , <https://identifiers.org/uniprot/E9PQJ2> , <https://identifiers.org/uniprot/C9JNE0> , <https://identifiers.org/uniprot/Q5T3E5> , <https://identifiers.org/uniprot/E7EUI6> , <https://identifiers.org/uniprot/A0A7I2V2F9> , <https://identifiers.org/uniprot/H7C4K3> , <https://identifiers.org/uniprot/C9JPK5> , <https://identifiers.org/uniprot/Q5T3E6> , <https://identifiers.org/uniprot/P05556> , <https://identifiers.org/uniprot/A0A7I2V2T4> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q14912083> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2813_r137944/DataNode/e370e> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/H7C4N8> , <http://purl.uniprot.org/uniprot/C9JNE0> , <http://purl.uniprot.org/uniprot/Q5T3E4> , <http://purl.uniprot.org/uniprot/H7C4K3> , <http://purl.uniprot.org/uniprot/E7EUI6> , <http://purl.uniprot.org/uniprot/A0A7I2V5T3> , <http://purl.uniprot.org/uniprot/A0A7I2V5Z8> , <http://purl.uniprot.org/uniprot/A0A7I2V2F9> , <http://purl.uniprot.org/uniprot/P05556> , <http://purl.uniprot.org/uniprot/E7EQW5> , <http://purl.uniprot.org/uniprot/E9PQJ2> , <http://purl.uniprot.org/uniprot/A0A7I2V2T4> , <http://purl.uniprot.org/uniprot/A0A7I2V348> , <http://purl.uniprot.org/uniprot/Q5T3E5> , <http://purl.uniprot.org/uniprot/Q5T3E6> , <http://purl.uniprot.org/uniprot/C9JPK5> , <http://purl.uniprot.org/uniprot/E9PLR6> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000150093> .

<http://rdf.wikipathways.org/Pathway/WP2813_r137944/WP/Interaction/ide93edc51>
        rdf:type            wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2813_r137944> ;
        dcterms:references  <https://identifiers.org/pubmed/19424592> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2813_r137944/Interaction/ide93edc51> ;
        wp:participants     <https://identifiers.org/ensembl/ENSG00000169554> , <https://identifiers.org/ensembl/ENSG00000105329> ;
        wp:source           <https://identifiers.org/ensembl/ENSG00000105329> ;
        wp:target           <https://identifiers.org/ensembl/ENSG00000169554> .

<https://identifiers.org/pubmed/17880691>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "17880691" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2813_r137944/WP/Interaction/idfb1f312f> , <http://rdf.wikipathways.org/Pathway/WP2813_r137944/WP/Interaction/id5b89ae88> , <http://rdf.wikipathways.org/Pathway/WP2813_r137944/WP/Interaction/id45a0e36b> , <http://rdf.wikipathways.org/Pathway/WP2813_r137944/WP/Interaction/id2ab32d01> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/17880691> .

<https://identifiers.org/ensembl/ENSG00000164362>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "TERT" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000164362> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000164362" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2813_r137944/WP/Interaction/ide8178db0> , <https://identifiers.org/wikipathways/WP2813_r137944> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000164362> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/7015> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/TERT> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A590UK92> , <https://identifiers.org/uniprot/O14746> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q15315135> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2813_r137944/DataNode/d3604> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A590UK92> , <http://purl.uniprot.org/uniprot/O14746> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000164362> .

<http://rdf.wikipathways.org/Pathway/WP2813_r137944/WP/Interaction/id1aac8138>
        rdf:type            wp:Interaction , wp:DirectedInteraction , wp:Inhibition ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2813_r137944> ;
        dcterms:references  <https://identifiers.org/pubmed/19424592> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2813_r137944/Interaction/id1aac8138> ;
        wp:participants     <https://identifiers.org/ensembl/ENSG00000198976> , <https://identifiers.org/ensembl/ENSG00000169554> ;
        wp:source           <https://identifiers.org/ensembl/ENSG00000169554> ;
        wp:target           <https://identifiers.org/ensembl/ENSG00000198976> .

<https://identifiers.org/ensembl/ENSG00000142208>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "AKT1" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000142208> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000142208" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2813_r137944/WP/Interaction/idb7af60b8> , <https://identifiers.org/wikipathways/WP2813_r137944> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000142208> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/207> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/AKT1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/G3V2I6> , <https://identifiers.org/uniprot/A0A804HJM6> , <https://identifiers.org/uniprot/A0A087WY56> , <https://identifiers.org/uniprot/G3V3X1> , <https://identifiers.org/uniprot/B0LPE5> , <https://identifiers.org/uniprot/P31749> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q17816452> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2813_r137944/DataNode/f4a65> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/G3V3X1> , <http://purl.uniprot.org/uniprot/G3V2I6> , <http://purl.uniprot.org/uniprot/A0A087WY56> , <http://purl.uniprot.org/uniprot/P31749> , <http://purl.uniprot.org/uniprot/A0A804HJM6> , <http://purl.uniprot.org/uniprot/B0LPE5> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000142208> .

<https://identifiers.org/pubmed/14668814>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "14668814" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2813_r137944> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/14668814> .

<https://identifiers.org/ensembl/ENSG00000110092>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "CCND1" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000110092> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000110092" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2813_r137944/WP/Interaction/idadeab32b> , <https://identifiers.org/wikipathways/WP2813_r137944> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000110092> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/595> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/CCND1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/F5H437> , <https://identifiers.org/uniprot/P24385> , <https://identifiers.org/uniprot/Q6FI00> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q15311861> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2813_r137944/DataNode/f17fe> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q6FI00> , <http://purl.uniprot.org/uniprot/P24385> , <http://purl.uniprot.org/uniprot/F5H437> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000110092> .

<http://rdf.wikipathways.org/Pathway/WP2813_r137944/WP/Interaction/id18d6867f>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2813_r137944> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2813_r137944/Interaction/id18d6867f> ;
        wp:participants   <https://identifiers.org/wikipathways/WP2817> , <https://identifiers.org/wikipathways/WP2814> ;
        wp:source         <https://identifiers.org/wikipathways/WP2814> ;
        wp:target         <https://identifiers.org/wikipathways/WP2817> .

<https://identifiers.org/wikipathways/WP2813>
        rdf:type            wp:DataNode , wp:Pathway ;
        rdfs:label          "Embryonic development" ;
        dc:identifier       <https://identifiers.org/wikipathways/WP2813> ;
        dc:source           "WikiPathways" ;
        dcterms:identifier  "WP2813" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2813_r137944/WP/Interaction/idf2b8f67f> , <https://identifiers.org/wikipathways/WP2813_r137944> ;
        pav:hasVersion      <https://identifiers.org/wikipathways/WP2813_r137944> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2813_r137944/DataNode/e1bfa> ;
        foaf:page           <https://www.wikipathways.org/instance/WP2813> .

<http://rdf.wikipathways.org/Pathway/WP2813_r137944/WP/Interaction/idadeab32b>
        rdf:type            wp:Interaction , wp:DirectedInteraction , wp:Inhibition ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2813_r137944> ;
        dcterms:references  <https://identifiers.org/pubmed/19424592> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2813_r137944/Interaction/idadeab32b> ;
        wp:participants     <https://identifiers.org/ensembl/ENSG00000169554> , <https://identifiers.org/ensembl/ENSG00000110092> ;
        wp:source           <https://identifiers.org/ensembl/ENSG00000169554> ;
        wp:target           <https://identifiers.org/ensembl/ENSG00000110092> .

<https://identifiers.org/wikipathways/WP2813_r137944>
        rdf:type                wp:Pathway , skos:Collection ;
        dc:identifier           <https://identifiers.org/wikipathways/WP2813> ;
        dc:source               "WikiPathways" ;
        dc:title                "Mammary gland development: embryonic development - stage 1 of 4"@en ;
        dcterms:description     "The mammary gland development can be subdivided into four stages of development: (1) embryonic development, (2) puberty, (3) pregnancy and lactation and (4) involution. In the embryonic development, a pair of mammary lines (ectoderm) arises, which gives origin to a pair of placodes. Then, each placode penetrates the underlying mesoderm. This results in the formation of the primary mammary gland [Smalley et al](http://www.ncbi.nlm.nih.gov/pubmed/14668814).\nNRG3 is a signal for placode formation. Besides that, it influences cell fate: it binds to its receptor, ERBB4, and induces MYC, which decreases expression of the integrins ITGA6 and ITGB1. The result is a change in cell adhesion and proliferation and consequent exit from the stem cell compartment [Panchal et al](http://www.ncbi.nlm.nih.gov/pubmed/17880691).\nAnother process that should be highlighted in the embryonic development is the epithelial to mesenchymal transition (EMT). ZEB2 is an EMT regulator. It represses many genes (eg. CCND1, SFRP1, MIR200A, MIR200B, MIR429, TERT, CDH1, CLDN4 and ALPL), and also upregulates mesenchymal markers [Katoh et al](http://www.ncbi.nlm.nih.gov/pubmed/19424592). CCND1 and SFRP1 are related to cell proliferation, and SFRP1 are also related to WNT signaling pathway. MIR200A, MIR200B and MIR429 are microRNAs. TERT is responsible for elongation of telomere ends. CDH1 and CLDN4 are associated with cell adhesion, and ALPL may play a role in skeletal mineralization. Many genes modulate ZEB2. Some of these are shown in the figure [Katoh et al](http://www.ncbi.nlm.nih.gov/pubmed/19424592). TGFB1, TNF and IL1 are cytokines and AKT1 plays a role in many processes like cell proliferation, survival and growth. Hedgehog signals upregulate ZEB2 via TGFB1 [Katoh et al](http://www.ncbi.nlm.nih.gov/pubmed/19424592)." ;
        dcterms:identifier      "WP2813" ;
        dcterms:references      <https://identifiers.org/pubmed/14668814> ;
        cito:cites              <https://identifiers.org/pubmed/14668814> , <https://identifiers.org/pubmed/19424592> , <https://identifiers.org/pubmed/17880691> ;
        wp:cellTypeOntologyTag  obo:CL_0000014 , obo:CL_0000314 ;
        wp:isAbout              <http://rdf.wikipathways.org/Pathway/WP2813_r137944> ;
        wp:ontologyTag          wp:Curation:AnalysisCollection , obo:CL_0000014 , obo:CL_0000314 , obo:PW_0000004 ;
        wp:organism             obo:NCBITaxon_9606 ;
        wp:organismName         "Homo sapiens" ;
        wp:pathwayOntologyTag   obo:PW_0000004 ;
        foaf:img                <https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=svg&pwTitle=Pathway:WP2813&oldid=137944> , <https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=png&pwTitle=Pathway:WP2813&oldid=137944> ;
        foaf:page               <http://www.wikipathways.org/instance/WP2813_r137944> .

<http://rdf.wikipathways.org/Pathway/WP2813_r137944/WP/Interaction/id7bde5174>
        rdf:type            wp:Interaction , wp:DirectedInteraction , wp:Inhibition ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2813_r137944> ;
        dcterms:references  <https://identifiers.org/pubmed/19424592> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2813_r137944/Interaction/id7bde5174> ;
        wp:participants     <https://identifiers.org/ensembl/ENSG00000207730> , <https://identifiers.org/ensembl/ENSG00000169554> ;
        wp:source           <https://identifiers.org/ensembl/ENSG00000169554> ;
        wp:target           <https://identifiers.org/ensembl/ENSG00000207730> .

<https://identifiers.org/ensembl/ENSG00000198976>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "MIR429" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000198976> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000198976" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2813_r137944/WP/Interaction/id1aac8138> , <https://identifiers.org/wikipathways/WP2813_r137944> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000198976> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/554210> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/MIR429> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18059104> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2813_r137944/DataNode/a39ec> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000198976> .

<http://rdf.wikipathways.org/Pathway/WP2813_r137944/WP/Interaction/idf2b8f67f>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2813_r137944> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2813_r137944/Interaction/idf2b8f67f> ;
        wp:participants   <https://identifiers.org/wikipathways/WP2814> , <https://identifiers.org/wikipathways/WP2813> ;
        wp:source         <https://identifiers.org/wikipathways/WP2813> ;
        wp:target         <https://identifiers.org/wikipathways/WP2814> .
