@prefix biopax:  <http://www.biopax.org/release/biopax-level3.owl#> .
@prefix cito:    <http://purl.org/spar/cito/> .
@prefix dc:      <http://purl.org/dc/elements/1.1/> .
@prefix dcterms: <http://purl.org/dc/terms/> .
@prefix foaf:    <http://xmlns.com/foaf/0.1/> .
@prefix freq:    <http://purl.org/cld/freq/> .
@prefix gpml:    <http://vocabularies.wikipathways.org/gpml#> .
@prefix obo:     <http://purl.obolibrary.org/obo/> .
@prefix owl:     <http://www.w3.org/2002/07/owl#> .
@prefix pav:     <http://purl.org/pav/> .
@prefix prov:    <http://www.w3.org/ns/prov#> .
@prefix rdf:     <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix rdfs:    <http://www.w3.org/2000/01/rdf-schema#> .
@prefix skos:    <http://www.w3.org/2004/02/skos/core#> .
@prefix void:    <http://rdfs.org/ns/void#> .
@prefix wp:      <http://vocabularies.wikipathways.org/wp#> .
@prefix wprdf:   <http://rdf.wikipathways.org/> .
@prefix xsd:     <http://www.w3.org/2001/XMLSchema#> .

<http://rdf.wikipathways.org/Pathway/WP3627_r140002/WP/Interaction/id2a2a40f>
        rdf:type          wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP3627_r140002> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP3627_r140002/Interaction/id2a2a40f> ;
        wp:participants   <https://identifiers.org/chebi/CHEBI:16881> .

<http://rdf.wikipathways.org/Pathway/WP3627_r140002/WP/Interaction/idd75cad3a>
        rdf:type          wp:Conversion , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP3627_r140002> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP3627_r140002/Interaction/idd75cad3a> ;
        wp:participants   <https://identifiers.org/chebi/CHEBI:17840> , <https://identifiers.org/chebi/CHEBI:16881> ;
        wp:source         <https://identifiers.org/chebi/CHEBI:16881> ;
        wp:target         <https://identifiers.org/chebi/CHEBI:17840> .

<https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=png&pwTitle=Pathway:WP3627&oldid=140002>
        rdf:type        foaf:Image ;
        dcterms:format  "image/png" .

<https://identifiers.org/pubmed/19234110>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "19234110" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP3627_r140002> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/19234110> .

<https://identifiers.org/chebi/CHEBI:16881>
        rdf:type            wp:Metabolite , wp:DataNode ;
        rdfs:label          "indole" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/SIKJAQJRHWYJAI-UHFFFAOYSA-N> ;
        dc:identifier       <https://identifiers.org/chebi/CHEBI:16881> ;
        dc:source           "ChEBI" ;
        dcterms:identifier  "CHEBI:16881" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP3627_r140002/WP/Interaction/id2a2a40f> , <http://rdf.wikipathways.org/Pathway/WP3627_r140002/WP/Interaction/iddfa826dd> , <http://rdf.wikipathways.org/Pathway/WP3627_r140002/WP/Interaction/id92cc91db> , <https://identifiers.org/wikipathways/WP3627_r140002> , <http://rdf.wikipathways.org/Pathway/WP3627_r140002/WP/Interaction/id9d000f1a> , <http://rdf.wikipathways.org/Pathway/WP3627_r140002/WP/Interaction/idd75cad3a> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:16881> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/776> ;
        wp:bdbHmdb          <https://identifiers.org/hmdb/HMDB0000738> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/SIKJAQJRHWYJAI-UHFFFAOYSA-N> ;
        wp:bdbKeggCompound  <https://identifiers.org/kegg.compound/C00463> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID798> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q319541> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP3627_r140002/DataNode/dfda2> , <http://rdf.wikipathways.org/Pathway/WP3627_r140002/DataNode/a9db4> , <http://rdf.wikipathways.org/Pathway/WP3627_r140002/DataNode/b2018> ;
        foaf:page           <https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:16881> .

<https://identifiers.org/wikipathways/WP3627>
        pav:hasVersion  <https://identifiers.org/wikipathways/WP3627_r140002> .

<http://rdf.wikipathways.org/Pathway/WP3627_r140002/WP/Interaction/id14d637fe>
        rdf:type          wp:Conversion , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP3627_r140002> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP3627_r140002/Interaction/id14d637fe> ;
        wp:participants   <https://identifiers.org/chebi/CHEBI:43355> , <https://identifiers.org/chebi/CHEBI:17840> ;
        wp:source         <https://identifiers.org/chebi/CHEBI:17840> ;
        wp:target         <https://identifiers.org/chebi/CHEBI:43355> .

<https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=svg&pwTitle=Pathway:WP3627&oldid=140002>
        rdf:type        foaf:Image ;
        dcterms:format  "image/svg+xml" .

<http://rdf.wikipathways.org/Pathway/WP3627_r140002/WP/Interaction/id9d000f1a>
        rdf:type          wp:Conversion , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP3627_r140002> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP3627_r140002/Interaction/id9d000f1a> ;
        wp:participants   <https://identifiers.org/chebi/CHEBI:43580> , <https://identifiers.org/chebi/CHEBI:16881> ;
        wp:source         <https://identifiers.org/chebi/CHEBI:16881> ;
        wp:target         <https://identifiers.org/chebi/CHEBI:43580> .

<http://rdf.wikipathways.org/Pathway/WP3627_r140002/WP/Interaction/idcad00256>
        rdf:type          wp:Catalysis , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP3627_r140002> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP3627_r140002/Interaction/idcad00256> ;
        wp:participants   <https://identifiers.org/ec-code/4.1.99.1> , <http://rdf.wikipathways.org/Pathway/WP3627_r140002/WP/Interaction/id92cc91db> ;
        wp:source         <https://identifiers.org/ec-code/4.1.99.1> ;
        wp:target         <http://rdf.wikipathways.org/Pathway/WP3627_r140002/WP/Interaction/id92cc91db> .

<http://rdf.wikipathways.org/Pathway/WP3627_r140002/WP/Interaction/idbdf66e04>
        rdf:type          wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP3627_r140002> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP3627_r140002/Interaction/idbdf66e04> ;
        wp:participants   <https://identifiers.org/chebi/CHEBI:43355> .

<https://identifiers.org/chebi/CHEBI:17840>
        rdf:type            wp:DataNode , wp:Metabolite ;
        rdfs:label          "indoxyl" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/PCKPVGOLPKLUHR-UHFFFAOYSA-N> ;
        dc:identifier       <https://identifiers.org/chebi/CHEBI:17840> ;
        dc:source           "ChEBI" ;
        dcterms:identifier  "CHEBI:17840" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP3627_r140002/WP/Interaction/idd75cad3a> , <http://rdf.wikipathways.org/Pathway/WP3627_r140002/WP/Interaction/id14d637fe> , <https://identifiers.org/wikipathways/WP3627_r140002> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:17840> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/45861> ;
        wp:bdbHmdb          <https://identifiers.org/hmdb/HMDB0004094> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/PCKPVGOLPKLUHR-UHFFFAOYSA-N> ;
        wp:bdbKeggCompound  <https://identifiers.org/kegg.compound/C05658> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID50591> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q423256> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP3627_r140002/DataNode/a1c11> ;
        foaf:page           <https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:17840> .

<https://identifiers.org/chebi/CHEBI:43355>
        rdf:type            wp:Metabolite , wp:DataNode ;
        rdfs:label          "indoxyl sulfate" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/BXFFHSIDQOFMLE-UHFFFAOYSA-N> ;
        dc:identifier       <https://identifiers.org/chebi/CHEBI:43355> ;
        dc:source           "ChEBI" ;
        dcterms:identifier  "CHEBI:43355" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP3627_r140002/WP/Interaction/idbdf66e04> , <https://identifiers.org/wikipathways/WP3627_r140002> , <http://rdf.wikipathways.org/Pathway/WP3627_r140002/WP/Interaction/id14d637fe> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:43355> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/9840> ;
        wp:bdbHmdb          <https://identifiers.org/hmdb/HMDB0000682> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/BXFFHSIDQOFMLE-UHFFFAOYSA-N> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID10258> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q11712146> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP3627_r140002/DataNode/e70f6> , <http://rdf.wikipathways.org/Pathway/WP3627_r140002/DataNode/ebdc8> ;
        foaf:page           <https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:43355> .

<https://identifiers.org/wikipathways/WP3627_r140002>
        rdf:type               wp:Pathway , skos:Collection ;
        dc:identifier          <https://identifiers.org/wikipathways/WP3627> ;
        dc:source              "WikiPathways" ;
        dc:title               "Gut-liver indole metabolism "@en ;
        dcterms:description    "Dietary tryptophane is metabolised by the gut microbiome to indole and IPA which reaches the human blood system. Indole is further metabolized into indoxyl sulfate which also reached the blood." ;
        dcterms:identifier     "WP3627" ;
        dcterms:references     <https://identifiers.org/pubmed/19234110> ;
        cito:cites             <https://identifiers.org/pubmed/19234110> ;
        wp:isAbout             <http://rdf.wikipathways.org/Pathway/WP3627_r140002> ;
        wp:ontologyTag         obo:PW_0000002 , wp:Curation:AnalysisCollection ;
        wp:organism            obo:NCBITaxon_9606 ;
        wp:organismName        "Homo sapiens" ;
        wp:pathwayOntologyTag  obo:PW_0000002 ;
        foaf:img               <https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=png&pwTitle=Pathway:WP3627&oldid=140002> , <https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=svg&pwTitle=Pathway:WP3627&oldid=140002> ;
        foaf:page              <http://www.wikipathways.org/instance/WP3627_r140002> .

<http://rdf.wikipathways.org/Pathway/WP3627_r140002/WP/Interaction/iddf31c619>
        rdf:type          wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP3627_r140002> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP3627_r140002/Interaction/iddf31c619> ;
        wp:participants   <https://identifiers.org/chebi/CHEBI:43580> .

<https://identifiers.org/pmc/PMC9015122>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed Central" ;
        dcterms:identifier  "PMC9015122" ;
        cito:cites          <https://identifiers.org/wikipathways/WP3627> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/PMC9015122> .

<https://identifiers.org/chebi/CHEBI:16828>
        rdf:type            wp:DataNode , wp:Metabolite ;
        rdfs:label          "dietary tryptophan" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/QIVBCDIJIAJPQS-VIFPVBQESA-N> ;
        dc:identifier       <https://identifiers.org/chebi/CHEBI:16828> ;
        dc:source           "ChEBI" ;
        dcterms:identifier  "CHEBI:16828" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP3627_r140002/WP/Interaction/id92cc91db> , <https://identifiers.org/wikipathways/WP3627_r140002> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:57912> , <https://identifiers.org/chebi/CHEBI:16828> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/6066> ;
        wp:bdbHmdb          <https://identifiers.org/hmdb/HMDB0000929> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/QIVBCDIJIAJPQS-VIFPVBQESA-N> ;
        wp:bdbKeggCompound  <https://identifiers.org/kegg.compound/C00078> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID6923516> , <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID6305> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q181003> , <http://www.wikidata.org/entity/Q106345470> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP3627_r140002/DataNode/f2d0d> ;
        foaf:page           <https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:16828> .

<https://identifiers.org/ensembl/ENSG00000130649>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "CYP2E1" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000130649> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000130649" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP3627_r140002/WP/Interaction/id16a530d0> , <https://identifiers.org/wikipathways/WP3627_r140002> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000130649> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/1571> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/CYP2E1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/H0Y7H4> , <https://identifiers.org/uniprot/F5H694> , <https://identifiers.org/uniprot/H0YGV5> , <https://identifiers.org/uniprot/P05181> , <https://identifiers.org/uniprot/H0Y593> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q14864434> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP3627_r140002/DataNode/f7b19> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P05181> , <http://purl.uniprot.org/uniprot/H0Y593> , <http://purl.uniprot.org/uniprot/H0YGV5> , <http://purl.uniprot.org/uniprot/F5H694> , <http://purl.uniprot.org/uniprot/H0Y7H4> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000130649> .

<https://identifiers.org/chebi/CHEBI:43580>
        rdf:type            wp:Metabolite , wp:DataNode ;
        rdfs:label          "IPA" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/GOLXRNDWAUTYKT-UHFFFAOYSA-N> ;
        dc:identifier       <https://identifiers.org/chebi/CHEBI:43580> ;
        dc:source           "ChEBI" ;
        dcterms:identifier  "CHEBI:43580" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP3627_r140002> , <http://rdf.wikipathways.org/Pathway/WP3627_r140002/WP/Interaction/iddf31c619> , <http://rdf.wikipathways.org/Pathway/WP3627_r140002/WP/Interaction/id9d000f1a> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:43580> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/3613> ;
        wp:bdbHmdb          <https://identifiers.org/hmdb/HMDB0002302> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/GOLXRNDWAUTYKT-UHFFFAOYSA-N> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID3744> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q21098993> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP3627_r140002/DataNode/aa46d> , <http://rdf.wikipathways.org/Pathway/WP3627_r140002/DataNode/ff98a> ;
        foaf:page           <https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:43580> .

<http://rdf.wikipathways.org/Pathway/WP3627_r140002/WP/Interaction/iddfa826dd>
        rdf:type          wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP3627_r140002> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP3627_r140002/Interaction/iddfa826dd> ;
        wp:participants   <https://identifiers.org/chebi/CHEBI:16881> .

obo:NCBITaxon_9606  obo:NCIT_C179773  "9606" .

<http://rdf.wikipathways.org/Pathway/WP3627_r140002/WP/Interaction/id16a530d0>
        rdf:type          wp:Catalysis , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP3627_r140002> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP3627_r140002/Interaction/id16a530d0> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000130649> , <http://rdf.wikipathways.org/Pathway/WP3627_r140002/WP/Interaction/idd75cad3a> ;
        wp:source         <https://identifiers.org/ensembl/ENSG00000130649> ;
        wp:target         <http://rdf.wikipathways.org/Pathway/WP3627_r140002/WP/Interaction/idd75cad3a> .

<https://identifiers.org/ec-code/4.1.99.1>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "tryptophanase" ;
        dc:identifier       <https://identifiers.org/ec-code/4.1.99.1> ;
        dc:source           "Enzyme Nomenclature" ;
        dcterms:identifier  "4.1.99.1" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP3627_r140002> , <http://rdf.wikipathways.org/Pathway/WP3627_r140002/WP/Interaction/idcad00256> ;
        wp:bdbRhea          <https://identifiers.org/rhea/19553> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP3627_r140002/DataNode/c2d11> ;
        owl:sameAs          <http://rhea-db.org/rhea/19553> ;
        foaf:page           <http://www.ebi.ac.uk/intenz/query?cmd=SearchEC&ec=4.1.99.1> .

<http://rdf.wikipathways.org/Pathway/WP3627_r140002/WP/Interaction/id92cc91db>
        rdf:type          wp:Conversion , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP3627_r140002> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP3627_r140002/Interaction/id92cc91db> ;
        wp:participants   <https://identifiers.org/chebi/CHEBI:16881> , <https://identifiers.org/chebi/CHEBI:16828> ;
        wp:source         <https://identifiers.org/chebi/CHEBI:16828> ;
        wp:target         <https://identifiers.org/chebi/CHEBI:16881> .
