@prefix biopax:  <http://www.biopax.org/release/biopax-level3.owl#> .
@prefix cito:    <http://purl.org/spar/cito/> .
@prefix dc:      <http://purl.org/dc/elements/1.1/> .
@prefix dcterms: <http://purl.org/dc/terms/> .
@prefix foaf:    <http://xmlns.com/foaf/0.1/> .
@prefix freq:    <http://purl.org/cld/freq/> .
@prefix gpml:    <http://vocabularies.wikipathways.org/gpml#> .
@prefix obo:     <http://purl.obolibrary.org/obo/> .
@prefix owl:     <http://www.w3.org/2002/07/owl#> .
@prefix pav:     <http://purl.org/pav/> .
@prefix prov:    <http://www.w3.org/ns/prov#> .
@prefix rdf:     <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix rdfs:    <http://www.w3.org/2000/01/rdf-schema#> .
@prefix skos:    <http://www.w3.org/2004/02/skos/core#> .
@prefix void:    <http://rdfs.org/ns/void#> .
@prefix wp:      <http://vocabularies.wikipathways.org/wp#> .
@prefix wprdf:   <http://rdf.wikipathways.org/> .
@prefix xsd:     <http://www.w3.org/2001/XMLSchema#> .

<https://identifiers.org/uniprot/Q64568>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "ATP2B3" ;
        dc:identifier       <https://identifiers.org/uniprot/Q64568> ;
        dc:source           "UniProtKB" ;
        dcterms:identifier  "Q64568" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id2ea7d1b6> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/ide77a5673> , <https://identifiers.org/wikipathways/WP4838_r140111> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSRNOG00000061304> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A8I6AKH9> , <https://identifiers.org/uniprot/A0A0G2K9Q6> , <https://identifiers.org/uniprot/A0A8L2UQ79> , <https://identifiers.org/uniprot/A0A8I5ZTE0> , <https://identifiers.org/uniprot/Q64568> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4838_r140111/DataNode/f7abe> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q64568> , <http://purl.uniprot.org/uniprot/A0A8I6AKH9> , <http://purl.uniprot.org/uniprot/A0A8L2UQ79> , <http://purl.uniprot.org/uniprot/A0A0G2K9Q6> , <http://purl.uniprot.org/uniprot/A0A8I5ZTE0> ;
        foaf:page           <http://www.uniprot.org/uniprot/Q64568> .

<https://identifiers.org/uniprot/Q01986>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "MAP2K1" ;
        dc:identifier       <https://identifiers.org/uniprot/Q01986> ;
        dc:source           "UniProtKB" ;
        dcterms:identifier  "Q01986" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/idfa400e42> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id8f21ab6e> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/iddcb5cced> , <https://identifiers.org/wikipathways/WP4838_r140111> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q01986> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4838_r140111/DataNode/ea13e> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q01986> ;
        foaf:page           <http://www.uniprot.org/uniprot/Q01986> .

<http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/ida2b656ac>
        rdf:type          wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4838_r140111> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4838_r140111/Interaction/ida2b656ac> ;
        wp:participants   <https://identifiers.org/chebi/CHEBI:27584> , <https://identifiers.org/uniprot/P22199> .

<http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id9ab3e07d>
        rdf:type          wp:Stimulation , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4838_r140111> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4838_r140111/Interaction/id9ab3e07d> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000121879> , <https://identifiers.org/uniprot/Q63132> ;
        wp:source         <https://identifiers.org/uniprot/Q63132> ;
        wp:target         <https://identifiers.org/ensembl/ENSG00000121879> .

<http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/idf083ef71>
        rdf:type          wp:Stimulation , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4838_r140111> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4838_r140111/Interaction/idf083ef71> ;
        wp:participants   <https://identifiers.org/uniprot/A0A087X0I9> , <https://identifiers.org/chebi/CHEBI:41847> ;
        wp:source         <https://identifiers.org/chebi/CHEBI:41847> ;
        wp:target         <https://identifiers.org/uniprot/A0A087X0I9> .

<https://identifiers.org/chebi/CHEBI:70982>
        rdf:type            wp:DataNode , wp:Metabolite ;
        rdfs:label          "ROS" ;
        dc:identifier       <https://identifiers.org/chebi/CHEBI:70982> ;
        dc:source           "ChEBI" ;
        dcterms:identifier  "CHEBI:70982" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id4d48de2b> , <https://identifiers.org/wikipathways/WP4838_r140111> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:70982> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4838_r140111/DataNode/fbc3e> ;
        foaf:page           <https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:70982> .

<http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id47c085b3>
        rdf:type          wp:Binding , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4838_r140111> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4838_r140111/Interaction/id47c085b3> ;
        wp:participants   <https://identifiers.org/chebi/CHEBI:29108> , <https://identifiers.org/ensembl/ENSG00000221823> ;
        wp:source         <https://identifiers.org/ensembl/ENSG00000221823> ;
        wp:target         <https://identifiers.org/chebi/CHEBI:29108> .

<http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/idb9b136bd>
        rdf:type          wp:Stimulation , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4838_r140111> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4838_r140111/Interaction/idb9b136bd> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000198793> , <https://identifiers.org/ensembl/ENSG00000142208> ;
        wp:source         <https://identifiers.org/ensembl/ENSG00000142208> ;
        wp:target         <https://identifiers.org/ensembl/ENSG00000198793> .

<http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id2ea7d1b6>
        rdf:type          wp:Inhibition , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4838_r140111> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4838_r140111/Interaction/id2ea7d1b6> ;
        wp:participants   <https://identifiers.org/uniprot/Q64568> , <https://identifiers.org/chebi/CHEBI:16595> ;
        wp:source         <https://identifiers.org/chebi/CHEBI:16595> ;
        wp:target         <https://identifiers.org/uniprot/Q64568> .

<http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id6445f2eb>
        rdf:type          wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4838_r140111> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4838_r140111/Interaction/id6445f2eb> ;
        wp:participants   <https://identifiers.org/chebi/CHEBI:29108> .

<https://identifiers.org/chebi/CHEBI:29101>
        rdf:type            wp:Metabolite , wp:DataNode ;
        rdfs:label          "3Na+" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/FKNQFGJONOIPTF-UHFFFAOYSA-N> ;
        dc:identifier       <https://identifiers.org/chebi/CHEBI:29101> ;
        dc:source           "ChEBI" ;
        dcterms:identifier  "CHEBI:29101" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4838_r140111> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:29101> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/899> ;
        wp:bdbHmdb          <https://identifiers.org/hmdb/HMDB0000588> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/FKNQFGJONOIPTF-UHFFFAOYSA-N> ;
        wp:bdbKeggCompound  <https://identifiers.org/kegg.compound/C01330> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID923> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q3154110> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4838_r140111/DataNode/f2824> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/DataNode/c26ea> ;
        foaf:page           <https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:29101> .

<https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=svg&pwTitle=Pathway:WP4838&oldid=140111>
        rdf:type        foaf:Image ;
        dcterms:format  "image/svg+xml" .

<https://identifiers.org/ensembl/ENSG00000064012>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "CASP8" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000064012> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000064012" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id5313c406> , <https://identifiers.org/wikipathways/WP4838_r140111> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id2c8985aa> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000064012> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/841> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/CASP8> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/F8WF39> , <https://identifiers.org/uniprot/E7ETB7> , <https://identifiers.org/uniprot/A0A8Q3WKY8> , <https://identifiers.org/uniprot/A0A8Q3SI66> , <https://identifiers.org/uniprot/E7EQ06> , <https://identifiers.org/uniprot/Q14790> , <https://identifiers.org/uniprot/C9JB29> , <https://identifiers.org/uniprot/H7C0E2> , <https://identifiers.org/uniprot/A0A024R3Z8> , <https://identifiers.org/uniprot/E7EQ01> , <https://identifiers.org/uniprot/A0A8Q3SID9> , <https://identifiers.org/uniprot/E7EVN1> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q14911965> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4838_r140111/DataNode/adc64> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/E7ETB7> , <http://purl.uniprot.org/uniprot/E7EVN1> , <http://purl.uniprot.org/uniprot/C9JB29> , <http://purl.uniprot.org/uniprot/E7EQ06> , <http://purl.uniprot.org/uniprot/Q14790> , <http://purl.uniprot.org/uniprot/F8WF39> , <http://purl.uniprot.org/uniprot/A0A8Q3SI66> , <http://purl.uniprot.org/uniprot/H7C0E2> , <http://purl.uniprot.org/uniprot/E7EQ01> , <http://purl.uniprot.org/uniprot/A0A8Q3WKY8> , <http://purl.uniprot.org/uniprot/A0A024R3Z8> , <http://purl.uniprot.org/uniprot/A0A8Q3SID9> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000064012> .

<http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id65c9ed15>
        rdf:type          wp:TranscriptionTranslation , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4838_r140111> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4838_r140111/Interaction/id65c9ed15> ;
        wp:participants   <https://identifiers.org/uniprot/Q15493> , <https://identifiers.org/uniprot/Q96JE7> ;
        wp:source         <https://identifiers.org/uniprot/Q96JE7> ;
        wp:target         <https://identifiers.org/uniprot/Q15493> .

<https://identifiers.org/uniprot/P21708>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "MAPK3" ;
        dc:identifier       <https://identifiers.org/uniprot/P21708> ;
        dc:source           "UniProtKB" ;
        dcterms:identifier  "P21708" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id35486ecb> , <https://identifiers.org/wikipathways/WP4838_r140111> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/P21708> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4838_r140111/DataNode/ee011> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P21708> ;
        foaf:page           <http://www.uniprot.org/uniprot/P21708> .

<http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/idd64e7382>
        rdf:type          wp:Binding , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4838_r140111> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4838_r140111/Interaction/idd64e7382> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000120868> , <https://identifiers.org/chebi/CHEBI:18070> ;
        wp:source         <https://identifiers.org/chebi/CHEBI:18070> ;
        wp:target         <https://identifiers.org/ensembl/ENSG00000120868> .

<https://identifiers.org/uniprot/P49187>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "MAPK10" ;
        dc:identifier       <https://identifiers.org/uniprot/P49187> ;
        dc:source           "UniProtKB" ;
        dcterms:identifier  "P49187" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4838_r140111> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/idb91bb510> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id13a4077d> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id4b1ff947> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/P49187> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4838_r140111/DataNode/e8c9e> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P49187> ;
        foaf:page           <http://www.uniprot.org/uniprot/P49187> .

<https://identifiers.org/chebi/CHEBI:16480>
        rdf:type            wp:Metabolite , wp:DataNode ;
        rdfs:label          "NO" , "Nitric oxide signaling" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/MWUXSHHQAYIFBG-UHFFFAOYSA-N> ;
        dc:identifier       <https://identifiers.org/chebi/CHEBI:16480> ;
        dc:source           "ChEBI" ;
        dcterms:identifier  "CHEBI:16480" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/idf0f1428> , <https://identifiers.org/wikipathways/WP4838_r140111> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:16480> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/127983> ;
        wp:bdbHmdb          <https://identifiers.org/hmdb/HMDB0003378> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/MWUXSHHQAYIFBG-UHFFFAOYSA-N> ;
        wp:bdbKeggCompound  <https://identifiers.org/kegg.compound/C00533> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID145068> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q207843> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4838_r140111/DataNode/d493a> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/DataNode/d07c8> ;
        foaf:page           <https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:16480> .

<http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id48a5596_1>
        rdf:type          wp:Stimulation , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4838_r140111> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4838_r140111/Interaction/id48a5596> ;
        wp:participants   <https://identifiers.org/uniprot/Q15493> , <https://identifiers.org/uniprot/A0A087X0I9> ;
        wp:source         <https://identifiers.org/uniprot/A0A087X0I9> ;
        wp:target         <https://identifiers.org/uniprot/Q15493> .

<http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id4368bef7>
        rdf:type          wp:Inhibition , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4838_r140111> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4838_r140111/Interaction/id4368bef7> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000121879> , <https://identifiers.org/uniprot/Q15493> ;
        wp:source         <https://identifiers.org/uniprot/Q15493> ;
        wp:target         <https://identifiers.org/ensembl/ENSG00000121879> .

<http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id6b58dd77>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4838_r140111> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4838_r140111/Interaction/id6b58dd77> ;
        wp:participants   <https://identifiers.org/uniprot/A0A087X0I9> , <https://identifiers.org/chebi/CHEBI:31991> ;
        wp:source         <https://identifiers.org/chebi/CHEBI:31991> ;
        wp:target         <https://identifiers.org/uniprot/A0A087X0I9> .

<http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id90262784>
        rdf:type          wp:Stimulation , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4838_r140111> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4838_r140111/Interaction/id90262784> ;
        wp:participants   <https://identifiers.org/chebi/CHEBI:18348> , <https://identifiers.org/uniprot/A0A0K0PUW7> ;
        wp:source         <https://identifiers.org/uniprot/A0A0K0PUW7> ;
        wp:target         <https://identifiers.org/chebi/CHEBI:18348> .

<http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id3233e920>
        rdf:type          wp:Stimulation , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4838_r140111> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4838_r140111/Interaction/id3233e920> ;
        wp:participants   <https://identifiers.org/uniprot/Q15493> , <https://identifiers.org/uniprot/A0A087X0I9> ;
        wp:source         <https://identifiers.org/uniprot/A0A087X0I9> ;
        wp:target         <https://identifiers.org/uniprot/Q15493> .

<https://identifiers.org/wikipathways/WP4838_r140111>
        rdf:type                skos:Collection , wp:Pathway ;
        dc:identifier           <https://identifiers.org/wikipathways/WP4838> ;
        dc:source               "WikiPathways" ;
        dc:title                "Regucalcin in proximal tubule epithelial kidney cells"@en ;
        dcterms:description     "This pathway includes the proximal tubule epithelial kidney cells (NRK52E cell) with a basolateral and apical side and other schematic illustrated organelles involved in the process of kidney function. The influence of regucalcin on the intra-and extracellular Ca²⁺ regulation is showed which are both involved in cell proliferation, ion transport and apoptosis and are important in normal kidney function. When the regulation of regucalcin and other factors are downregulated and suppressed, the kidney fails in functionality and so renal fibrosis will develop.  \nFirst of all, TGF-B (TGFB1) and TNF-a (TNFA) do have an impact on the activity of SMAD2/4 which has an impact on the development of a-SMA (ACTA2) that induced renal fibrosis. NF-kB (TNFSF11), stimulated by TNF-a, activates the transcription factor p65 (RELA) that induced the IL-8 expression which is involved in inflammatory pathways. On the other hand, regucalcin inhibits the a-SMA which means that the formation of renal fibrosis is inhibited. Further, TGF-B stimulates the caspase 8 (CASP8) that activates the cytochrome C which activate the apoptosis pathway. Also, here regucalcin function as an inhibitor for APAF1 that results in an inhibition of the apoptosis pathway and activate the BCL-2 (suppressor of apoptotic cell death). \nBesides the TGF-B and TNF-a pathway, there is an RTK pathway illustrated which activates the PI3K (PI3K3CA) and RAS (G3BP1) pathway for stimulation of the renal homeostasis, autophagy, protein and cell proliferation. According to Yamaguchi M. (2015), regucalcin activates the AKT1 to induce the renal homeostasis, autophagy and protein proliferation even further when PI3K is inhibited. The RTK pathway shows interaction with the cAMP pathway that stimulate the protein kinase A (PRKACA) and the PIP2 pathway that stimulate the protein kinase C (PRKCQ) and IP3. These all will stimulate Ca²⁺ release from the endoplasmic reticulum (ER).  This Ca²⁺ can migrate and enters the mitochondria through the Ca²⁺ uniporter (MCU) which results in the activation of mitochondrial biological processes or release of different mitochondrial factors. Hence, calcium controls and modulate cell apoptosis and inflammation. MAP3K pathway might be involved in the stimulation of RAF1 to induce the cell proliferation and the increase in apoptosis by inhibition of BCL-2 through JNK (MAPK10) which is also activated by ROS. \n\nCa²⁺ released by the ER can also bind to calmodulin to form the Ca²⁺/Calmodulin complex that stimulates IP3, JNK, NOS, RGPR—p117 (SEC16B) and NF1. The latter two proteins are involved in the enhancement of regucalcin gene expression. On the other hand, regucalcin can inhibit the activity of Ca²⁺/Calmodulin complex and the NOS. Normally, phosphodiesterase (PDE1B) binds cAMP that induced the degradation of cAMP which results in a decrease of protein kinase A that leads to a reduction of ER Ca²⁺ release. Regucalcin inhibits the phosphodiesterase in such a way that cAMP will not be degraded and the ER Ca²⁺ release can further occur. Remaining Ca²⁺ released from the ER can also transport to the microsomes, enters vis Ca²⁺ uniporter, to induce microsomal activities. This process of microsomal Ca²⁺ uptake can be diminished through the inhibition of IP3 kinase. \nRegucalcin is not only involved in the regulation of intracellular Ca²⁺ release or uptake, but also extracellular Ca²⁺ by stimulating the Ca²⁺/ATPase (ATP2B3) which leads to Ca²⁺ export. Besides that, the Na+/Ca²⁺ exchanger (SLC8A1) is important to be present on the basolateral membrane of the proximal tubule epithelial kidney cell to regulate the ion transport. On the apical membrane is the TRPV5 receptor present that regulate the import of Ca²⁺ from the lumen back into the kidney cell, but Ca²⁺ can also travel via paracellular transport. \nFurther, in the nucleus the regucalcin has an influence on the inhibition of the serine/threonine phosphate (PSP), tyrosine phosphatase (PTP) and calcineurin (PPP3R1) gene expression. Normally, PSP stimulates the protein kinase A- and so the ER Ca²⁺ release-, PTP stimulates the cell growth and differentiation and calcineurin will migrate to the cytoplasm for binding to the Ca²⁺ and stimulates the formation of Ca²⁺/Calmodulin complex. \nIn general, regucalcin regulates the factors and proteins involved in ion transport, cell proliferation and apoptosis. \nResearch is done on rats. \n" ;
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        wp:bdbWikidata      <http://www.wikidata.org/entity/Q17709258> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4838_r140111/DataNode/e14f1> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P62736> , <http://purl.uniprot.org/uniprot/F6UVQ4> , <http://purl.uniprot.org/uniprot/D2JYH4> , <http://purl.uniprot.org/uniprot/F6QUT6> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000107796> .

<http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id3faabd65>
        rdf:type          wp:Stimulation , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4838_r140111> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4838_r140111/Interaction/id3faabd65> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000132155> , <https://identifiers.org/uniprot/Q5U0Q1> ;
        wp:source         <https://identifiers.org/uniprot/Q5U0Q1> ;
        wp:target         <https://identifiers.org/ensembl/ENSG00000132155> .

<https://identifiers.org/uniprot/A0A087WVP0>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "RELA" ;
        dc:identifier       <https://identifiers.org/uniprot/A0A087WVP0> ;
        dc:source           "UniProtKB" ;
        dcterms:identifier  "A0A087WVP0" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/idfca38e9c> , <https://identifiers.org/wikipathways/WP4838_r140111> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A087WVP0> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4838_r140111/DataNode/b5e54> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A087WVP0> ;
        foaf:page           <http://www.uniprot.org/uniprot/A0A087WVP0> .

<http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id5313c406>
        rdf:type          wp:Stimulation , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4838_r140111> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4838_r140111/Interaction/id5313c406> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000064012> , <https://identifiers.org/ensembl/ENSG00000067182> ;
        wp:source         <https://identifiers.org/ensembl/ENSG00000067182> ;
        wp:target         <https://identifiers.org/ensembl/ENSG00000064012> .

<http://rdf.wikipathways.org/Pathway/WP4838_r140111/Complex/e1ca0>
        rdf:type          wp:Complex , wp:DataNode ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4838_r140111> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4838_r140111/Group/e1ca0> ;
        wp:participants   <https://identifiers.org/uniprot/P22199> , <https://identifiers.org/chebi/CHEBI:27584> .

<http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id82a94cb0>
        rdf:type          wp:Stimulation , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4838_r140111> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4838_r140111/Interaction/id82a94cb0> ;
        wp:participants   <https://identifiers.org/uniprot/Q5U0Q1> , <https://identifiers.org/uniprot/P27791> ;
        wp:source         <https://identifiers.org/uniprot/P27791> ;
        wp:target         <https://identifiers.org/uniprot/Q5U0Q1> .

<http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id5ce6b13c>
        rdf:type          wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4838_r140111> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4838_r140111/Interaction/id5ce6b13c> ;
        wp:participants   <https://identifiers.org/uniprot/Q15493> .

<http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/ide231f86c>
        rdf:type          wp:Stimulation , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4838_r140111> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4838_r140111/Interaction/ide231f86c> ;
        wp:participants   <https://identifiers.org/uniprot/A0A087X0I9> , <https://identifiers.org/chebi/CHEBI:37537> ;
        wp:source         <https://identifiers.org/chebi/CHEBI:37537> ;
        wp:target         <https://identifiers.org/uniprot/A0A087X0I9> .

<http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/iddcb5cced>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4838_r140111> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4838_r140111/Interaction/iddcb5cced> ;
        wp:participants   <https://identifiers.org/uniprot/Q01986> , <https://identifiers.org/uniprot/Q99683> ;
        wp:source         <https://identifiers.org/uniprot/Q99683> ;
        wp:target         <https://identifiers.org/uniprot/Q01986> .

<https://identifiers.org/chebi/CHEBI:37537>
        rdf:type            wp:Metabolite , wp:DataNode ;
        rdfs:label          "PMA" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/PHEDXBVPIONUQT-RGYGYFBISA-N> ;
        dc:identifier       <https://identifiers.org/chebi/CHEBI:37537> ;
        dc:source           "ChEBI" ;
        dcterms:identifier  "CHEBI:37537" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/ide231f86c> , <https://identifiers.org/wikipathways/WP4838_r140111> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:37537> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/25977> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/PHEDXBVPIONUQT-RGYGYFBISA-N> ;
        wp:bdbKeggCompound  <https://identifiers.org/kegg.compound/C05151> ;
        wp:bdbLipidMaps     <https://identifiers.org/lipidmaps/LMPR0104330002> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID27924> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q416716> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4838_r140111/DataNode/ae81d> ;
        owl:sameAs          <https://www.lipidmaps.org/rdf/LMPR0104330002> ;
        foaf:page           <https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:37537> .

<https://identifiers.org/uniprot/P22199>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "Cytoplasmic mineralocorticoid receptor" , "NR3C2" ;
        dc:identifier       <https://identifiers.org/uniprot/P22199> ;
        dc:source           "UniProtKB" ;
        dcterms:identifier  "P22199" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id5631c029> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/ida2b656ac> , <https://identifiers.org/wikipathways/WP4838_r140111> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/Complex/e1ca0> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/P22199> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4838_r140111/DataNode/e1e55> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/DataNode/d6440> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P22199> ;
        foaf:page           <http://www.uniprot.org/uniprot/P22199> .

<https://identifiers.org/ensembl/ENSG00000152266>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "PTH" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000152266> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000152266" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/idd63705db> , <https://identifiers.org/wikipathways/WP4838_r140111> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000152266> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/5741> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/PTH> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/P01270> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q14860476> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4838_r140111/DataNode/a5bb8> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P01270> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000152266> .

<http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id4d903a10>
        rdf:type          wp:Inhibition , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4838_r140111> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4838_r140111/Interaction/id4d903a10> ;
        wp:participants   <https://identifiers.org/uniprot/A0A087X0I9> , <https://identifiers.org/uniprot/Q15493> ;
        wp:source         <https://identifiers.org/uniprot/Q15493> ;
        wp:target         <https://identifiers.org/uniprot/A0A087X0I9> .

<http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id1b41110>
        rdf:type          wp:Stimulation , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4838_r140111> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4838_r140111/Interaction/id1b41110> ;
        wp:participants   <https://identifiers.org/uniprot/Q5U0Q1> , <https://identifiers.org/uniprot/Q63132> ;
        wp:source         <https://identifiers.org/uniprot/Q63132> ;
        wp:target         <https://identifiers.org/uniprot/Q5U0Q1> .

<https://identifiers.org/ensembl/ENSG00000030110>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "BAK1" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000030110> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000030110" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id6abd344d> , <https://identifiers.org/wikipathways/WP4838_r140111> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/iddb2136ed> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000030110> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/578> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/BAK1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A0S2Z391> , <https://identifiers.org/uniprot/Q16611> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q14907689> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4838_r140111/DataNode/da909> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q16611> , <http://purl.uniprot.org/uniprot/A0A0S2Z391> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000030110> .

<http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id642aaaf7>
        rdf:type          wp:Stimulation , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4838_r140111> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4838_r140111/Interaction/id642aaaf7> ;
        wp:participants   <https://identifiers.org/uniprot/P27791> , <https://identifiers.org/chebi/CHEBI:17489> ;
        wp:source         <https://identifiers.org/chebi/CHEBI:17489> ;
        wp:target         <https://identifiers.org/uniprot/P27791> .

<http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id30405fe>
        rdf:type          wp:Stimulation , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4838_r140111> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4838_r140111/Interaction/id30405fe> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000142208> , <https://identifiers.org/ensembl/ENSG00000121879> ;
        wp:source         <https://identifiers.org/ensembl/ENSG00000121879> ;
        wp:target         <https://identifiers.org/ensembl/ENSG00000142208> .

<https://identifiers.org/ensembl/ENSG00000157764>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "BRAF" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000157764> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000157764" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/idd8fdce83> , <https://identifiers.org/wikipathways/WP4838_r140111> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id1e5bb836> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000157764> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/673> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/BRAF> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/P15056> , <https://identifiers.org/uniprot/H7C4S5> , <https://identifiers.org/uniprot/H7C560> , <https://identifiers.org/uniprot/A0A2R8Y679> , <https://identifiers.org/uniprot/A0A2R8Y467> , <https://identifiers.org/uniprot/A0A2R8Y8E0> , <https://identifiers.org/uniprot/H7C5K3> , <https://identifiers.org/uniprot/A0A2R8YDP5> , <https://identifiers.org/uniprot/A0A2R8Y492> , <https://identifiers.org/uniprot/A0A2U3TZI2> , <https://identifiers.org/uniprot/A0A2R8YES9> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q17853226> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4838_r140111/DataNode/f9f68> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A2R8Y467> , <http://purl.uniprot.org/uniprot/H7C4S5> , <http://purl.uniprot.org/uniprot/A0A2R8Y679> , <http://purl.uniprot.org/uniprot/H7C560> , <http://purl.uniprot.org/uniprot/A0A2R8YDP5> , <http://purl.uniprot.org/uniprot/P15056> , <http://purl.uniprot.org/uniprot/A0A2R8Y492> , <http://purl.uniprot.org/uniprot/H7C5K3> , <http://purl.uniprot.org/uniprot/A0A2U3TZI2> , <http://purl.uniprot.org/uniprot/A0A2R8YES9> , <http://purl.uniprot.org/uniprot/A0A2R8Y8E0> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000157764> .

<https://identifiers.org/ensembl/ENSG00000105329>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "TGFB1" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000105329> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000105329" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4838_r140111> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/idbfe3f207> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000105329> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/7040> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/TGFB1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A7I2V5Z9> , <https://identifiers.org/uniprot/A0A7I2YQL8> , <https://identifiers.org/uniprot/A0A499FJK2> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q14904613> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4838_r140111/DataNode/cc0b7> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A499FJK2> , <http://purl.uniprot.org/uniprot/A0A7I2YQL8> , <http://purl.uniprot.org/uniprot/A0A7I2V5Z9> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000105329> .

<https://identifiers.org/uniprot/Q15493>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "RGN" ;
        dc:identifier       <https://identifiers.org/uniprot/Q15493> ;
        dc:source           "UniProtKB" ;
        dcterms:identifier  "Q15493" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id48a5596_1> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id4368bef7> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id661b6de3> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id888eb0e3> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id73c196c4> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id65c9ed15> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id5ce6b13c> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id8a2331de> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/idde2e76fc> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id3233e920> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/idc2741289> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id1599595e> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/idec4a322d> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id334a79e6> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/ide77a5673> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id9e167b65> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id2ad47f71> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/idb2ccea40> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/idae681be0> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id9b6de802> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id90b65c6> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id2ec0ecf0> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id48a5596_2> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id4d903a10> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id1cbe8491> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id1144e5c1> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id47bff0d9> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id7731baa4> , <https://identifiers.org/wikipathways/WP4838_r140111> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000130988> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/9104> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/RGN> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q15493> , <https://identifiers.org/uniprot/V9HWF8> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4838_r140111/DataNode/c7e6c> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/DataNode/c2147> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/DataNode/ac32b> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/V9HWF8> , <http://purl.uniprot.org/uniprot/Q15493> ;
        foaf:page           <http://www.uniprot.org/uniprot/Q15493> .

<http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/idd8fdce83>
        rdf:type          wp:Stimulation , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4838_r140111> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4838_r140111/Interaction/idd8fdce83> ;
        wp:participants   <https://identifiers.org/chebi/CHEBI:28398> , <https://identifiers.org/ensembl/ENSG00000157764> ;
        wp:source         <https://identifiers.org/ensembl/ENSG00000157764> ;
        wp:target         <https://identifiers.org/chebi/CHEBI:28398> .

<http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id9b6de802>
        rdf:type          wp:Inhibition , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4838_r140111> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4838_r140111/Interaction/id9b6de802> ;
        wp:participants   <https://identifiers.org/uniprot/Q15493> , <https://identifiers.org/ensembl/ENSG00000141646> ;
        wp:source         <https://identifiers.org/ensembl/ENSG00000141646> ;
        wp:target         <https://identifiers.org/uniprot/Q15493> .

<https://identifiers.org/uniprot/Q5U0Q1>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "G3BP1" ;
        dc:identifier       <https://identifiers.org/uniprot/Q5U0Q1> ;
        dc:source           "UniProtKB" ;
        dcterms:identifier  "Q5U0Q1" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4838_r140111> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id82a94cb0> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id3faabd65> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id1e5bb836> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id1b41110> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000145907> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/10146> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/G3BP1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A7I2V2S5> , <https://identifiers.org/uniprot/A0A7I2V5H1> , <https://identifiers.org/uniprot/A0A7I2V5M7> , <https://identifiers.org/uniprot/Q5U0Q1> , <https://identifiers.org/uniprot/A0A7I2YQC2> , <https://identifiers.org/uniprot/E5RH00> , <https://identifiers.org/uniprot/A0A7I2V3C4> , <https://identifiers.org/uniprot/A0A7I2V548> , <https://identifiers.org/uniprot/A0A7I2YQU8> , <https://identifiers.org/uniprot/A0A7I2YQB1> , <https://identifiers.org/uniprot/A0A7I2YQQ8> , <https://identifiers.org/uniprot/E5RIF8> , <https://identifiers.org/uniprot/A0A7I2YQP3> , <https://identifiers.org/uniprot/A0A7I2YQN9> , <https://identifiers.org/uniprot/A0A7I2V3Y4> , <https://identifiers.org/uniprot/A0A7I2YQM1> , <https://identifiers.org/uniprot/E5RJU8> , <https://identifiers.org/uniprot/A0A7I2YQH0> , <https://identifiers.org/uniprot/A0A7I2V533> , <https://identifiers.org/uniprot/E5RI46> , <https://identifiers.org/uniprot/A0A7I2V651> , <https://identifiers.org/uniprot/A0A7I2V4Y8> , <https://identifiers.org/uniprot/A0A7I2V4D8> , <https://identifiers.org/uniprot/A0A7I2V274> , <https://identifiers.org/uniprot/E5RH42> , <https://identifiers.org/uniprot/A0A7I2V2V1> , <https://identifiers.org/uniprot/A0A7I2V2X7> , <https://identifiers.org/uniprot/A0A7I2V496> , <https://identifiers.org/uniprot/A0A7I2YQF2> , <https://identifiers.org/uniprot/A0A7I2V494> , <https://identifiers.org/uniprot/Q13283> , <https://identifiers.org/uniprot/A0A7I2V326> , <https://identifiers.org/uniprot/A0A7P0P2U7> , <https://identifiers.org/uniprot/A0A7I2V565> , <https://identifiers.org/uniprot/A0A7I2YQR4> , <https://identifiers.org/uniprot/A0A7I2V3V2> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4838_r140111/DataNode/de98f> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A7I2V3C4> , <http://purl.uniprot.org/uniprot/E5RH42> , <http://purl.uniprot.org/uniprot/A0A7I2V533> , <http://purl.uniprot.org/uniprot/A0A7P0P2U7> , <http://purl.uniprot.org/uniprot/A0A7I2V5H1> , <http://purl.uniprot.org/uniprot/Q5U0Q1> , <http://purl.uniprot.org/uniprot/A0A7I2YQC2> , <http://purl.uniprot.org/uniprot/A0A7I2V4D8> , <http://purl.uniprot.org/uniprot/E5RIF8> , <http://purl.uniprot.org/uniprot/A0A7I2V494> , <http://purl.uniprot.org/uniprot/A0A7I2V4Y8> , <http://purl.uniprot.org/uniprot/A0A7I2YQB1> , <http://purl.uniprot.org/uniprot/E5RH00> , <http://purl.uniprot.org/uniprot/E5RJU8> , <http://purl.uniprot.org/uniprot/A0A7I2YQF2> , <http://purl.uniprot.org/uniprot/A0A7I2V2X7> , <http://purl.uniprot.org/uniprot/A0A7I2YQN9> , <http://purl.uniprot.org/uniprot/A0A7I2V274> , <http://purl.uniprot.org/uniprot/A0A7I2V3Y4> , <http://purl.uniprot.org/uniprot/E5RI46> , <http://purl.uniprot.org/uniprot/A0A7I2YQM1> , <http://purl.uniprot.org/uniprot/A0A7I2V496> , <http://purl.uniprot.org/uniprot/A0A7I2V5M7> , <http://purl.uniprot.org/uniprot/A0A7I2YQH0> , <http://purl.uniprot.org/uniprot/A0A7I2V565> , <http://purl.uniprot.org/uniprot/A0A7I2V3V2> , <http://purl.uniprot.org/uniprot/A0A7I2YQU8> , <http://purl.uniprot.org/uniprot/A0A7I2V651> , <http://purl.uniprot.org/uniprot/A0A7I2V326> , <http://purl.uniprot.org/uniprot/A0A7I2V2S5> , <http://purl.uniprot.org/uniprot/A0A7I2V2V1> , <http://purl.uniprot.org/uniprot/A0A7I2YQP3> , <http://purl.uniprot.org/uniprot/A0A7I2YQR4> , <http://purl.uniprot.org/uniprot/A0A7I2V548> , <http://purl.uniprot.org/uniprot/Q13283> , <http://purl.uniprot.org/uniprot/A0A7I2YQQ8> ;
        foaf:page           <http://www.uniprot.org/uniprot/Q5U0Q1> .

<https://identifiers.org/chebi/CHEBI:41847>
        rdf:type            wp:Metabolite , wp:DataNode ;
        rdfs:label          "DAG" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/UHUSDOQQWJGJQS-QNGWXLTQSA-N> ;
        dc:identifier       <https://identifiers.org/chebi/CHEBI:41847> ;
        dc:source           "ChEBI" ;
        dcterms:identifier  "CHEBI:41847" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id6519529> , <https://identifiers.org/wikipathways/WP4838_r140111> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/idf083ef71> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:41847> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/7822655> ;
        wp:bdbHmdb          <https://identifiers.org/hmdb/HMDB0007158> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/UHUSDOQQWJGJQS-QNGWXLTQSA-N> ;
        wp:bdbLipidMaps     <https://identifiers.org/lipidmaps/LMGL02010037> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID9543705> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q27120437> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4838_r140111/DataNode/c2e78> ;
        owl:sameAs          <https://www.lipidmaps.org/rdf/LMGL02010037> , <https://swisslipids.org/rdf/SLM_000120873> ;
        foaf:page           <https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:41847> .

<http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/ide62d4df>
        rdf:type          wp:Stimulation , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4838_r140111> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4838_r140111/Interaction/ide62d4df> ;
        wp:participants   <https://identifiers.org/uniprot/Q8NE86> , <https://identifiers.org/chebi/CHEBI:3324> ;
        wp:source         <https://identifiers.org/chebi/CHEBI:3324> ;
        wp:target         <https://identifiers.org/uniprot/Q8NE86> .

<http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id81e99da5>
        rdf:type          wp:Stimulation , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4838_r140111> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4838_r140111/Interaction/id81e99da5> ;
        wp:participants   <https://identifiers.org/chebi/CHEBI:28398> , <https://identifiers.org/ensembl/ENSG00000132155> ;
        wp:source         <https://identifiers.org/ensembl/ENSG00000132155> ;
        wp:target         <https://identifiers.org/chebi/CHEBI:28398> .

<https://identifiers.org/ensembl/ENSG00000100030>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "MAPK1" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000100030> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000100030" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4838_r140111> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id4b1ff947> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id8f21ab6e> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000100030> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/5594> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/MAPK1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q1HBJ4> , <https://identifiers.org/uniprot/P28482> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q15317730> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4838_r140111/DataNode/c4f15> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P28482> , <http://purl.uniprot.org/uniprot/Q1HBJ4> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000100030> .

<https://identifiers.org/ensembl/ENSG00000141646>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "SMAD4" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000141646> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000141646" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id9b6de802> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id41600c79> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id6c69329e> , <https://identifiers.org/wikipathways/WP4838_r140111> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000141646> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/4089> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/SMAD4> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/K7ES96> , <https://identifiers.org/uniprot/K7EIU8> , <https://identifiers.org/uniprot/K7EL18> , <https://identifiers.org/uniprot/K7ENG1> , <https://identifiers.org/uniprot/K7ELK2> , <https://identifiers.org/uniprot/K7EIJ2> , <https://identifiers.org/uniprot/Q13485> , <https://identifiers.org/uniprot/K7EL15> , <https://identifiers.org/uniprot/A0A087WUF3> , <https://identifiers.org/uniprot/A0A024R274> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q14904154> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4838_r140111/DataNode/bb227> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A024R274> , <http://purl.uniprot.org/uniprot/K7ENG1> , <http://purl.uniprot.org/uniprot/K7ES96> , <http://purl.uniprot.org/uniprot/K7EIU8> , <http://purl.uniprot.org/uniprot/K7EL15> , <http://purl.uniprot.org/uniprot/A0A087WUF3> , <http://purl.uniprot.org/uniprot/Q13485> , <http://purl.uniprot.org/uniprot/K7EIJ2> , <http://purl.uniprot.org/uniprot/K7ELK2> , <http://purl.uniprot.org/uniprot/K7EL18> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000141646> .

<https://identifiers.org/ensembl/ENSG00000120659>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "TNFSF11" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000120659> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000120659" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/idfca38e9c> , <https://identifiers.org/wikipathways/WP4838_r140111> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/idc06b7824> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id888eb0e3> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id47bff0d9> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000120659> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/8600> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/TNFSF11> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q5T9Y4> , <https://identifiers.org/uniprot/O14788> , <https://identifiers.org/uniprot/Q54A98> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q14905567> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4838_r140111/DataNode/abedc> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/O14788> , <http://purl.uniprot.org/uniprot/Q5T9Y4> , <http://purl.uniprot.org/uniprot/Q54A98> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000120659> .

<http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id8a1f053e>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4838_r140111> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4838_r140111/Interaction/id8a1f053e> ;
        wp:participants   <https://identifiers.org/uniprot/P27791> , <https://identifiers.org/chebi/CHEBI:31991> ;
        wp:source         <https://identifiers.org/chebi/CHEBI:31991> ;
        wp:target         <https://identifiers.org/uniprot/P27791> .

<https://identifiers.org/chebi/CHEBI:28398>
        rdf:type            wp:Metabolite , wp:DataNode ;
        rdfs:label          "MEK" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/ZWEHNKRNPOVVGH-UHFFFAOYSA-N> ;
        dc:identifier       <https://identifiers.org/chebi/CHEBI:28398> ;
        dc:source           "ChEBI" ;
        dcterms:identifier  "CHEBI:28398" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/idd8fdce83> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id35486ecb> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id81e99da5> , <https://identifiers.org/wikipathways/WP4838_r140111> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:28398> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/6321> ;
        wp:bdbHmdb          <https://identifiers.org/hmdb/HMDB0000474> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/ZWEHNKRNPOVVGH-UHFFFAOYSA-N> ;
        wp:bdbKeggCompound  <https://identifiers.org/kegg.compound/C02845> ;
        wp:bdbLipidMaps     <https://identifiers.org/lipidmaps/LMFA12000043> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID6569> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q372291> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4838_r140111/DataNode/bca3a> ;
        owl:sameAs          <https://www.lipidmaps.org/rdf/LMFA12000043> ;
        foaf:page           <https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:28398> .

<http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/idc06b7824>
        rdf:type          wp:Stimulation , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4838_r140111> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4838_r140111/Interaction/idc06b7824> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000120659> , <https://identifiers.org/ensembl/ENSG00000067182> ;
        wp:source         <https://identifiers.org/ensembl/ENSG00000067182> ;
        wp:target         <https://identifiers.org/ensembl/ENSG00000120659> .

<https://identifiers.org/uniprot/B3VK56>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "NOS1" ;
        dc:identifier       <https://identifiers.org/uniprot/B3VK56> ;
        dc:source           "UniProtKB" ;
        dcterms:identifier  "B3VK56" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4838_r140111> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/idc207fa86> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/idec4a322d> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000089250> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/4842> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/NOS1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/P29475> , <https://identifiers.org/uniprot/B3VK56> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4838_r140111/DataNode/d9033> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P29475> , <http://purl.uniprot.org/uniprot/B3VK56> ;
        foaf:page           <http://www.uniprot.org/uniprot/B3VK56> .

<https://identifiers.org/uniprot/P36897>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "TGFBR1" ;
        dc:identifier       <https://identifiers.org/uniprot/P36897> ;
        dc:source           "UniProtKB" ;
        dcterms:identifier  "P36897" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/idbfe3f207> , <https://identifiers.org/wikipathways/WP4838_r140111> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/idb8513fd8> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id41600c79> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000106799> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/7046> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/TGFBR1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A8V8TMI6> , <https://identifiers.org/uniprot/F8VRH6> , <https://identifiers.org/uniprot/F8VXZ5> , <https://identifiers.org/uniprot/H0YHS4> , <https://identifiers.org/uniprot/B4DY26> , <https://identifiers.org/uniprot/F8VVC4> , <https://identifiers.org/uniprot/Q5T7S2> , <https://identifiers.org/uniprot/F8W1R9> , <https://identifiers.org/uniprot/F8W0K6> , <https://identifiers.org/uniprot/A0A8V8TMH4> , <https://identifiers.org/uniprot/P36897> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4838_r140111/DataNode/bee6f> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/F8W0K6> , <http://purl.uniprot.org/uniprot/F8VXZ5> , <http://purl.uniprot.org/uniprot/Q5T7S2> , <http://purl.uniprot.org/uniprot/A0A8V8TMI6> , <http://purl.uniprot.org/uniprot/A0A8V8TMH4> , <http://purl.uniprot.org/uniprot/P36897> , <http://purl.uniprot.org/uniprot/B4DY26> , <http://purl.uniprot.org/uniprot/H0YHS4> , <http://purl.uniprot.org/uniprot/F8W1R9> , <http://purl.uniprot.org/uniprot/F8VRH6> , <http://purl.uniprot.org/uniprot/F8VVC4> ;
        foaf:page           <http://www.uniprot.org/uniprot/P36897> .

<http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/idc207fa86>
        rdf:type          wp:Catalysis , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4838_r140111> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4838_r140111/Interaction/idc207fa86> ;
        wp:participants   <https://identifiers.org/uniprot/B3VK56> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/idf0f1428> ;
        wp:source         <https://identifiers.org/uniprot/B3VK56> ;
        wp:target         <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/idf0f1428> .

<http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id47bff0d9>
        rdf:type          wp:Inhibition , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4838_r140111> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4838_r140111/Interaction/id47bff0d9> ;
        wp:participants   <https://identifiers.org/uniprot/Q15493> , <https://identifiers.org/ensembl/ENSG00000120659> ;
        wp:source         <https://identifiers.org/ensembl/ENSG00000120659> ;
        wp:target         <https://identifiers.org/uniprot/Q15493> .

<http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/idb2ccea40>
        rdf:type          wp:Stimulation , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4838_r140111> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4838_r140111/Interaction/idb2ccea40> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000142208> , <https://identifiers.org/uniprot/Q15493> ;
        wp:source         <https://identifiers.org/uniprot/Q15493> ;
        wp:target         <https://identifiers.org/ensembl/ENSG00000142208> .

<http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/idd63705db>
        rdf:type          wp:Binding , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4838_r140111> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4838_r140111/Interaction/idd63705db> ;
        wp:participants   <https://identifiers.org/uniprot/A0A0K0PUW7> , <https://identifiers.org/ensembl/ENSG00000152266> ;
        wp:source         <https://identifiers.org/ensembl/ENSG00000152266> ;
        wp:target         <https://identifiers.org/uniprot/A0A0K0PUW7> .

<https://identifiers.org/chebi/CHEBI:27584>
        rdf:type            wp:Metabolite , wp:DataNode ;
        rdfs:label          "Aldosterone" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/PQSUYGKTWSAVDQ-ZVIOFETBSA-N> ;
        dc:identifier       <https://identifiers.org/chebi/CHEBI:27584> ;
        dc:source           "ChEBI" ;
        dcterms:identifier  "CHEBI:27584" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/ida2b656ac> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id5631c029> , <https://identifiers.org/wikipathways/WP4838_r140111> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/Complex/e1ca0> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:27584> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/5633> ;
        wp:bdbHmdb          <https://identifiers.org/hmdb/HMDB0000037> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/PQSUYGKTWSAVDQ-ZVIOFETBSA-N> ;
        wp:bdbKeggCompound  <https://identifiers.org/kegg.compound/C01780> ;
        wp:bdbLipidMaps     <https://identifiers.org/lipidmaps/LMST02030026> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID5839> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q184564> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4838_r140111/DataNode/d688e> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/DataNode/f5679> ;
        owl:sameAs          <https://www.lipidmaps.org/rdf/LMST02030026> , <https://swisslipids.org/rdf/SLM_000485683> ;
        foaf:page           <https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:27584> .

<http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id465985a4>
        rdf:type          wp:Stimulation , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4838_r140111> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4838_r140111/Interaction/id465985a4> ;
        wp:participants   <https://identifiers.org/chebi/CHEBI:29108> , <https://identifiers.org/chebi/CHEBI:16595> ;
        wp:source         <https://identifiers.org/chebi/CHEBI:16595> ;
        wp:target         <https://identifiers.org/chebi/CHEBI:29108> .

<https://identifiers.org/ensembl/ENSG00000127412>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "TRPV5" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000127412> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000127412" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4838_r140111> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000127412> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/56302> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/TRPV5> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A0A6YY98> , <https://identifiers.org/uniprot/A0A0J9YXI7> , <https://identifiers.org/uniprot/H7C2J6> , <https://identifiers.org/uniprot/Q9NQA5> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4838_r140111/DataNode/ac1e0> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/H7C2J6> , <http://purl.uniprot.org/uniprot/A0A0J9YXI7> , <http://purl.uniprot.org/uniprot/A0A0A6YY98> , <http://purl.uniprot.org/uniprot/Q9NQA5> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000127412> .

<https://identifiers.org/uniprot/Q96JE7>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "SEC16B" ;
        dc:identifier       <https://identifiers.org/uniprot/Q96JE7> ;
        dc:source           "UniProtKB" ;
        dcterms:identifier  "Q96JE7" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4838_r140111> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id65c9ed15> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000120341> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/89866> , <https://identifiers.org/ncbigene/111240474> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/SEC16B> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/H0YE70> , <https://identifiers.org/uniprot/U3KQ39> , <https://identifiers.org/uniprot/E9PK14> , <https://identifiers.org/uniprot/Q96JE7> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4838_r140111/DataNode/e8aaa> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q96JE7> , <http://purl.uniprot.org/uniprot/E9PK14> , <http://purl.uniprot.org/uniprot/U3KQ39> , <http://purl.uniprot.org/uniprot/H0YE70> ;
        foaf:page           <http://www.uniprot.org/uniprot/Q96JE7> .

<https://identifiers.org/uniprot/A0A0K0PUW7>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "FFAR3" ;
        dc:identifier       <https://identifiers.org/uniprot/A0A0K0PUW7> ;
        dc:source           "UniProtKB" ;
        dcterms:identifier  "A0A0K0PUW7" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4838_r140111> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/idf08db64b> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/idd63705db> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id6d323aed> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id90262784> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000185897> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/2865> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/FFAR3> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/O14843> , <https://identifiers.org/uniprot/A0A0K0PUW7> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4838_r140111/DataNode/d1095> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A0K0PUW7> , <http://purl.uniprot.org/uniprot/O14843> ;
        foaf:page           <http://www.uniprot.org/uniprot/A0A0K0PUW7> .

<https://identifiers.org/ensembl/ENSG00000142208>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "AKT1" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000142208> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000142208" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id30405fe> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/idb9b136bd> , <https://identifiers.org/wikipathways/WP4838_r140111> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/idb2ccea40> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000142208> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/207> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/AKT1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/G3V2I6> , <https://identifiers.org/uniprot/A0A804HJM6> , <https://identifiers.org/uniprot/A0A087WY56> , <https://identifiers.org/uniprot/G3V3X1> , <https://identifiers.org/uniprot/B0LPE5> , <https://identifiers.org/uniprot/P31749> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q17816452> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4838_r140111/DataNode/d2657> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/G3V3X1> , <http://purl.uniprot.org/uniprot/G3V2I6> , <http://purl.uniprot.org/uniprot/A0A087WY56> , <http://purl.uniprot.org/uniprot/P31749> , <http://purl.uniprot.org/uniprot/A0A804HJM6> , <http://purl.uniprot.org/uniprot/B0LPE5> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000142208> .

obo:NCBITaxon_9606  obo:NCIT_C179773  "9606" .

<http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id48a5596_2>
        rdf:type          wp:Stimulation , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4838_r140111> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4838_r140111/Interaction/id48a5596> ;
        wp:participants   <https://identifiers.org/uniprot/Q15493> , <https://identifiers.org/uniprot/A0A087X0I9> ;
        wp:source         <https://identifiers.org/uniprot/Q15493> ;
        wp:target         <https://identifiers.org/uniprot/A0A087X0I9> .

<http://rdf.wikipathways.org/Pathway/WP4838_r140111/ComplexBinding/e1ca0>
        rdf:type          wp:ComplexBinding , wp:Binding , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4838_r140111> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4838_r140111/Group/e1ca0> ;
        wp:participants   <https://identifiers.org/uniprot/P22199> , <https://identifiers.org/chebi/CHEBI:27584> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/Complex/e1ca0> .

<https://identifiers.org/chebi/CHEBI:45951>
        rdf:type            wp:Metabolite , wp:DataNode ;
        rdfs:label          "Trifluoperazine" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/ZEWQUBUPAILYHI-UHFFFAOYSA-N> ;
        dc:identifier       <https://identifiers.org/chebi/CHEBI:45951> ;
        dc:source           "ChEBI" ;
        dcterms:identifier  "CHEBI:45951" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4838_r140111> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:45951> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/5365> ;
        wp:bdbHmdb          <https://identifiers.org/hmdb/HMDB0014969> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/ZEWQUBUPAILYHI-UHFFFAOYSA-N> ;
        wp:bdbKeggCompound  <https://identifiers.org/kegg.compound/C07168> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID5566> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q1752915> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4838_r140111/DataNode/b39a5> ;
        foaf:page           <https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:45951> .

<http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/idde2e76fc>
        rdf:type          wp:Inhibition , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4838_r140111> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4838_r140111/Interaction/idde2e76fc> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000120868> , <https://identifiers.org/uniprot/Q15493> ;
        wp:source         <https://identifiers.org/uniprot/Q15493> ;
        wp:target         <https://identifiers.org/ensembl/ENSG00000120868> .

<http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id73c196c4>
        rdf:type          wp:Inhibition , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4838_r140111> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4838_r140111/Interaction/id73c196c4> ;
        wp:participants   <https://identifiers.org/uniprot/A0A024RB59> , <https://identifiers.org/uniprot/Q15493> ;
        wp:source         <https://identifiers.org/uniprot/Q15493> ;
        wp:target         <https://identifiers.org/uniprot/A0A024RB59> .

<http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/ida0a35855>
        rdf:type          wp:Stimulation , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4838_r140111> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4838_r140111/Interaction/ida0a35855> ;
        wp:participants   <https://identifiers.org/uniprot/A0A087X0I9> , <https://identifiers.org/chebi/CHEBI:18035> ;
        wp:source         <https://identifiers.org/chebi/CHEBI:18035> ;
        wp:target         <https://identifiers.org/uniprot/A0A087X0I9> .

<https://identifiers.org/chebi/CHEBI:18070>
        rdf:type            wp:DataNode , wp:Metabolite ;
        rdfs:label          "Cytochrome C" ;
        dc:identifier       <https://identifiers.org/chebi/CHEBI:18070> ;
        dc:source           "ChEBI" ;
        dcterms:identifier  "CHEBI:18070" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id2c8985aa> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id6c3f20fd> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id6abd344d> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id4d77759> , <https://identifiers.org/wikipathways/WP4838_r140111> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/idd64e7382> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:18070> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q408223> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4838_r140111/DataNode/fc643> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/DataNode/d4f44> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/DataNode/f063d> ;
        foaf:page           <https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:18070> .

<http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id219e31f8>
        rdf:type          wp:Stimulation , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4838_r140111> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4838_r140111/Interaction/id219e31f8> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000107796> , <https://identifiers.org/ensembl/ENSG00000067182> ;
        wp:source         <https://identifiers.org/ensembl/ENSG00000067182> ;
        wp:target         <https://identifiers.org/ensembl/ENSG00000107796> .

<http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id93599b57>
        rdf:type          wp:Conversion , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4838_r140111> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4838_r140111/Interaction/id93599b57> ;
        wp:participants   <https://identifiers.org/chebi/CHEBI:17489> , <https://identifiers.org/chebi/CHEBI:16027> ;
        wp:source         <https://identifiers.org/chebi/CHEBI:16027> ;
        wp:target         <https://identifiers.org/chebi/CHEBI:17489> .

<https://identifiers.org/ensembl/ENSG00000175387>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "SMAD2" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000175387> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000175387" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id1144e5c1> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/idb8513fd8> , <https://identifiers.org/wikipathways/WP4838_r140111> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000175387> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/4087> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/SMAD2> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/B7Z5N5> , <https://identifiers.org/uniprot/K7ERC7> , <https://identifiers.org/uniprot/Q53XR6> , <https://identifiers.org/uniprot/K7ESI8> , <https://identifiers.org/uniprot/Q15796> , <https://identifiers.org/uniprot/K7EJX0> , <https://identifiers.org/uniprot/K7EL92> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q14903945> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4838_r140111/DataNode/b937c> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/K7ERC7> , <http://purl.uniprot.org/uniprot/Q15796> , <http://purl.uniprot.org/uniprot/K7EL92> , <http://purl.uniprot.org/uniprot/B7Z5N5> , <http://purl.uniprot.org/uniprot/Q53XR6> , <http://purl.uniprot.org/uniprot/K7ESI8> , <http://purl.uniprot.org/uniprot/K7EJX0> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000175387> .

<http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/idfa400e42>
        rdf:type          wp:Stimulation , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4838_r140111> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4838_r140111/Interaction/idfa400e42> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000132155> , <https://identifiers.org/uniprot/Q01986> ;
        wp:source         <https://identifiers.org/uniprot/Q01986> ;
        wp:target         <https://identifiers.org/ensembl/ENSG00000132155> .

<http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id2ec0ecf0>
        rdf:type          wp:Stimulation , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4838_r140111> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4838_r140111/Interaction/id2ec0ecf0> ;
        wp:participants   <https://identifiers.org/uniprot/Q15493> , <https://identifiers.org/chebi/CHEBI:29108> ;
        wp:source         <https://identifiers.org/chebi/CHEBI:29108> ;
        wp:target         <https://identifiers.org/uniprot/Q15493> .

<http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id7731baa4>
        rdf:type          wp:Stimulation , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4838_r140111> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4838_r140111/Interaction/id7731baa4> ;
        wp:participants   <https://identifiers.org/uniprot/Q8NE86> , <https://identifiers.org/uniprot/Q15493> ;
        wp:source         <https://identifiers.org/uniprot/Q15493> ;
        wp:target         <https://identifiers.org/uniprot/Q8NE86> .

<http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/idbfe3f207>
        rdf:type          wp:Binding , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4838_r140111> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4838_r140111/Interaction/idbfe3f207> ;
        wp:participants   <https://identifiers.org/uniprot/P36897> , <https://identifiers.org/ensembl/ENSG00000105329> ;
        wp:source         <https://identifiers.org/ensembl/ENSG00000105329> ;
        wp:target         <https://identifiers.org/uniprot/P36897> .

<https://identifiers.org/uniprot/Q63132>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "ROS1" ;
        dc:identifier       <https://identifiers.org/uniprot/Q63132> ;
        dc:source           "UniProtKB" ;
        dcterms:identifier  "Q63132" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id1b41110> , <https://identifiers.org/wikipathways/WP4838_r140111> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id9ab3e07d> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q63132> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4838_r140111/DataNode/ff7a0> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q63132> ;
        foaf:page           <http://www.uniprot.org/uniprot/Q63132> .

<https://identifiers.org/chebi/CHEBI:26523>
        rdf:type            wp:DataNode , wp:Metabolite ;
        rdfs:label          "ROS" ;
        dc:identifier       <https://identifiers.org/chebi/CHEBI:26523> ;
        dc:source           "ChEBI" ;
        dcterms:identifier  "CHEBI:26523" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/idb91bb510> , <https://identifiers.org/wikipathways/WP4838_r140111> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id4d48de2b> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:26523> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q424361> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4838_r140111/DataNode/b0de8> ;
        foaf:page           <https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:26523> .

<https://identifiers.org/pubmed/19536897>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "19536897" ;
        dcterms:isPartOf    <https://identifiers.org/ensembl/ENSG00000221823> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/19536897> .

<https://identifiers.org/uniprot/KW-0788>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "SENP8" ;
        dc:identifier       <https://identifiers.org/uniprot/KW-0788> ;
        dc:source           "UniProtKB" ;
        dcterms:identifier  "KW-0788" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4838_r140111> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id9e167b65> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/KW-0788> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4838_r140111/DataNode/c460c> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/KW-0788> ;
        foaf:page           <http://www.uniprot.org/uniprot/KW-0788> .

<http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id35486ecb>
        rdf:type          wp:Stimulation , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4838_r140111> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4838_r140111/Interaction/id35486ecb> ;
        wp:participants   <https://identifiers.org/uniprot/P21708> , <https://identifiers.org/chebi/CHEBI:28398> ;
        wp:source         <https://identifiers.org/chebi/CHEBI:28398> ;
        wp:target         <https://identifiers.org/uniprot/P21708> .

<http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id8a2331de>
        rdf:type          wp:Stimulation , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4838_r140111> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4838_r140111/Interaction/id8a2331de> ;
        wp:participants   <https://identifiers.org/chebi/CHEBI:29108> , <https://identifiers.org/uniprot/Q15493> ;
        wp:source         <https://identifiers.org/uniprot/Q15493> ;
        wp:target         <https://identifiers.org/chebi/CHEBI:29108> .

<http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id13a4077d>
        rdf:type          wp:Inhibition , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4838_r140111> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4838_r140111/Interaction/id13a4077d> ;
        wp:participants   <https://identifiers.org/chebi/CHEBI:133022> , <https://identifiers.org/uniprot/P49187> ;
        wp:source         <https://identifiers.org/uniprot/P49187> ;
        wp:target         <https://identifiers.org/chebi/CHEBI:133022> .

<https://identifiers.org/uniprot/P27791>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "PRKACA" ;
        dc:identifier       <https://identifiers.org/uniprot/P27791> ;
        dc:source           "UniProtKB" ;
        dcterms:identifier  "P27791" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id642aaaf7> , <https://identifiers.org/wikipathways/WP4838_r140111> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id82a94cb0> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id8a1f053e> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/idb002d12f> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/P27791> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4838_r140111/DataNode/f39af> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P27791> ;
        foaf:page           <http://www.uniprot.org/uniprot/P27791> .

<http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/idae681be0>
        rdf:type          wp:Inhibition , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4838_r140111> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4838_r140111/Interaction/idae681be0> ;
        wp:participants   <https://identifiers.org/chebi/CHEBI:52242> , <https://identifiers.org/uniprot/Q15493> ;
        wp:source         <https://identifiers.org/uniprot/Q15493> ;
        wp:target         <https://identifiers.org/chebi/CHEBI:52242> .

<https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=png&pwTitle=Pathway:WP4838&oldid=140111>
        rdf:type        foaf:Image ;
        dcterms:format  "image/png" .

<https://identifiers.org/chebi/CHEBI:34956>
        rdf:type            wp:DataNode , wp:Metabolite ;
        rdfs:label          "Ruthenium red" ;
        dc:identifier       <https://identifiers.org/chebi/CHEBI:34956> ;
        dc:source           "ChEBI" ;
        dcterms:identifier  "CHEBI:34956" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4838_r140111> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:34956> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/17345980> ;
        wp:bdbKeggCompound  <https://identifiers.org/kegg.compound/C13932> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID16218584> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q424006> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4838_r140111/DataNode/f07dc> ;
        foaf:page           <https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:34956> .

<https://identifiers.org/uniprot/A0A024RB59>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "PDE1B" ;
        dc:identifier       <https://identifiers.org/uniprot/A0A024RB59> ;
        dc:source           "UniProtKB" ;
        dcterms:identifier  "A0A024RB59" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4838_r140111> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id3a9a2100> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id73c196c4> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000123360> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/5153> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/PDE1B> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/F8VZK3> , <https://identifiers.org/uniprot/A0A024RB59> , <https://identifiers.org/uniprot/A0A087WTW8> , <https://identifiers.org/uniprot/Q01064> , <https://identifiers.org/uniprot/B4DK72> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4838_r140111/DataNode/e42d4> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/B4DK72> , <http://purl.uniprot.org/uniprot/A0A024RB59> , <http://purl.uniprot.org/uniprot/F8VZK3> , <http://purl.uniprot.org/uniprot/Q01064> , <http://purl.uniprot.org/uniprot/A0A087WTW8> ;
        foaf:page           <http://www.uniprot.org/uniprot/A0A024RB59> .

<http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id6b9db392>
        rdf:type          wp:Stimulation , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4838_r140111> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4838_r140111/Interaction/id6b9db392> ;
        wp:participants   <https://identifiers.org/uniprot/P42574> , <https://identifiers.org/ensembl/ENSG00000132906> ;
        wp:source         <https://identifiers.org/ensembl/ENSG00000132906> ;
        wp:target         <https://identifiers.org/uniprot/P42574> .

<https://identifiers.org/uniprot/P42574>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "CASP3" ;
        dc:identifier       <https://identifiers.org/uniprot/P42574> ;
        dc:source           "UniProtKB" ;
        dcterms:identifier  "P42574" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4838_r140111> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id6b9db392> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id661b6de3> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000164305> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/836> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/CASP3> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/C9JXR7> , <https://identifiers.org/uniprot/A8MVM1> , <https://identifiers.org/uniprot/P42574> , <https://identifiers.org/uniprot/A0A8V8TPU5> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4838_r140111/DataNode/cc8b0> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A8MVM1> , <http://purl.uniprot.org/uniprot/P42574> , <http://purl.uniprot.org/uniprot/A0A8V8TPU5> , <http://purl.uniprot.org/uniprot/C9JXR7> ;
        foaf:page           <http://www.uniprot.org/uniprot/P42574> .

<http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id1cbe8491>
        rdf:type          wp:Inhibition , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4838_r140111> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4838_r140111/Interaction/id1cbe8491> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000107796> , <https://identifiers.org/uniprot/Q15493> ;
        wp:source         <https://identifiers.org/uniprot/Q15493> ;
        wp:target         <https://identifiers.org/ensembl/ENSG00000107796> .

<https://identifiers.org/chebi/CHEBI:52242>
        rdf:type            wp:DataNode , wp:Metabolite ;
        rdfs:label          "PTP" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/XJKSTNDFUHDPQJ-UHFFFAOYSA-N> ;
        dc:identifier       <https://identifiers.org/chebi/CHEBI:52242> ;
        dc:source           "ChEBI" ;
        dcterms:identifier  "CHEBI:52242" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/idae681be0> , <https://identifiers.org/wikipathways/WP4838_r140111> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:52242> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/6848> ;
        wp:bdbHmdb          <https://identifiers.org/hmdb/HMDB0256056> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/XJKSTNDFUHDPQJ-UHFFFAOYSA-N> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID7115> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q20965188> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4838_r140111/DataNode/d4398> ;
        foaf:page           <https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:52242> .

<http://rdf.wikipathways.org/Pathway/WP4838_r140111/Complex/eeb78>
        rdf:type          wp:Complex , wp:DataNode ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4838_r140111> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4838_r140111/Group/eeb78> ;
        wp:participants   <https://identifiers.org/chebi/CHEBI:29108> , <https://identifiers.org/chebi/CHEBI:3324> .

<http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id4d77759>
        rdf:type          wp:Stimulation , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4838_r140111> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4838_r140111/Interaction/id4d77759> ;
        wp:participants   <https://identifiers.org/chebi/CHEBI:18070> ;
        wp:source         <https://identifiers.org/chebi/CHEBI:18070> ;
        wp:target         <https://identifiers.org/chebi/CHEBI:18070> .

<https://identifiers.org/ensembl/ENSG00000121879>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "PI3K3CA" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000121879> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000121879" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4838_r140111> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id30405fe> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id9ab3e07d> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id4368bef7> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000121879> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/5290> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/PIK3CA> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/P42336> , <https://identifiers.org/uniprot/A0A2R8Y2F6> , <https://identifiers.org/uniprot/A0A6Q8PGV1> , <https://identifiers.org/uniprot/C9JAM9> , <https://identifiers.org/uniprot/C9J951> , <https://identifiers.org/uniprot/A0A6Q8PGN9> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q14887700> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4838_r140111/DataNode/a90f1> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/C9J951> , <http://purl.uniprot.org/uniprot/C9JAM9> , <http://purl.uniprot.org/uniprot/P42336> , <http://purl.uniprot.org/uniprot/A0A2R8Y2F6> , <http://purl.uniprot.org/uniprot/A0A6Q8PGV1> , <http://purl.uniprot.org/uniprot/A0A6Q8PGN9> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000121879> .

<http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/idf08db64b>
        rdf:type          wp:Stimulation , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4838_r140111> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4838_r140111/Interaction/idf08db64b> ;
        wp:participants   <https://identifiers.org/chebi/CHEBI:16027> , <https://identifiers.org/uniprot/A0A0K0PUW7> ;
        wp:source         <https://identifiers.org/uniprot/A0A0K0PUW7> ;
        wp:target         <https://identifiers.org/chebi/CHEBI:16027> .

<https://identifiers.org/ensembl/ENSG00000198793>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "MTOR" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000198793> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000198793" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4838_r140111> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/idb9b136bd> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000198793> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/2475> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/MTOR> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A8V8TRG9> , <https://identifiers.org/uniprot/A0A8V8TR74> , <https://identifiers.org/uniprot/A0A8V8TQN3> , <https://identifiers.org/uniprot/A0A8V8TQM6> , <https://identifiers.org/uniprot/A0A8V8TQ52> , <https://identifiers.org/uniprot/P42345> , <https://identifiers.org/uniprot/A0A8V8TQP2> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q14876086> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4838_r140111/DataNode/c7ced> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P42345> , <http://purl.uniprot.org/uniprot/A0A8V8TQP2> , <http://purl.uniprot.org/uniprot/A0A8V8TQ52> , <http://purl.uniprot.org/uniprot/A0A8V8TQM6> , <http://purl.uniprot.org/uniprot/A0A8V8TRG9> , <http://purl.uniprot.org/uniprot/A0A8V8TR74> , <http://purl.uniprot.org/uniprot/A0A8V8TQN3> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000198793> .

<http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/idfca38e9c>
        rdf:type          wp:Stimulation , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4838_r140111> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4838_r140111/Interaction/idfca38e9c> ;
        wp:participants   <https://identifiers.org/uniprot/A0A087WVP0> , <https://identifiers.org/ensembl/ENSG00000120659> ;
        wp:source         <https://identifiers.org/ensembl/ENSG00000120659> ;
        wp:target         <https://identifiers.org/uniprot/A0A087WVP0> .

<https://identifiers.org/ensembl/ENSG00000067182>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "TNFRSF1A" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000067182> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000067182" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/idc06b7824> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id5313c406> , <https://identifiers.org/wikipathways/WP4838_r140111> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id5443ab72> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id219e31f8> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000067182> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/7132> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/TNFRSF1A> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/F5GWJ4> , <https://identifiers.org/uniprot/F5H061> , <https://identifiers.org/uniprot/F5H4T5> , <https://identifiers.org/uniprot/F5H7N1> , <https://identifiers.org/uniprot/P19438> , <https://identifiers.org/uniprot/F5H6V7> , <https://identifiers.org/uniprot/A0A8V8TLL5> , <https://identifiers.org/uniprot/F5H6Z2> , <https://identifiers.org/uniprot/F5H8A6> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18032044> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4838_r140111/DataNode/d4b8d> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A8V8TLL5> , <http://purl.uniprot.org/uniprot/P19438> , <http://purl.uniprot.org/uniprot/F5H7N1> , <http://purl.uniprot.org/uniprot/F5GWJ4> , <http://purl.uniprot.org/uniprot/F5H6V7> , <http://purl.uniprot.org/uniprot/F5H061> , <http://purl.uniprot.org/uniprot/F5H4T5> , <http://purl.uniprot.org/uniprot/F5H8A6> , <http://purl.uniprot.org/uniprot/F5H6Z2> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000067182> .

<https://identifiers.org/uniprot/P01258>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "CALCA" ;
        dc:identifier       <https://identifiers.org/uniprot/P01258> ;
        dc:source           "UniProtKB" ;
        dcterms:identifier  "P01258" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4838_r140111> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id6d323aed> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000110680> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/796> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/CALCA> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/P01258> , <https://identifiers.org/uniprot/P06881> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4838_r140111/DataNode/e2787> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P06881> , <http://purl.uniprot.org/uniprot/P01258> ;
        foaf:page           <http://www.uniprot.org/uniprot/P01258> .

<https://identifiers.org/ensembl/ENSG00000132906>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "CASP9" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000132906> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000132906" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id7c10121f> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id6b9db392> , <https://identifiers.org/wikipathways/WP4838_r140111> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000132906> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/842> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/CASP9> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/H0Y3S8> , <https://identifiers.org/uniprot/Q5JRU8> , <https://identifiers.org/uniprot/F8VWA5> , <https://identifiers.org/uniprot/Q5JRU2> , <https://identifiers.org/uniprot/H0Y6Y2> , <https://identifiers.org/uniprot/A0A087WX72> , <https://identifiers.org/uniprot/P55211> , <https://identifiers.org/uniprot/F8VVS7> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q14907714> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4838_r140111/DataNode/af02b> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q5JRU8> , <http://purl.uniprot.org/uniprot/H0Y3S8> , <http://purl.uniprot.org/uniprot/H0Y6Y2> , <http://purl.uniprot.org/uniprot/F8VWA5> , <http://purl.uniprot.org/uniprot/P55211> , <http://purl.uniprot.org/uniprot/F8VVS7> , <http://purl.uniprot.org/uniprot/A0A087WX72> , <http://purl.uniprot.org/uniprot/Q5JRU2> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000132906> .

<http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id3a9a2100>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4838_r140111> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4838_r140111/Interaction/id3a9a2100> ;
        wp:participants   <https://identifiers.org/chebi/CHEBI:17489> , <https://identifiers.org/uniprot/A0A024RB59> ;
        wp:source         <https://identifiers.org/uniprot/A0A024RB59> ;
        wp:target         <https://identifiers.org/chebi/CHEBI:17489> .

<https://identifiers.org/chebi/CHEBI:29108>
        rdf:type            wp:DataNode , wp:Metabolite ;
        rdfs:label          "Ca²⁺" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/BHPQYMZQTOCNFJ-UHFFFAOYSA-N> ;
        dc:identifier       <https://identifiers.org/chebi/CHEBI:29108> ;
        dc:source           "ChEBI" ;
        dcterms:identifier  "CHEBI:29108" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id6445f2eb> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/idb002d12f> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/Complex/eeb78> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id2ec0ecf0> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id465985a4> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id8a2331de> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id47c085b3> , <https://identifiers.org/wikipathways/WP4838_r140111> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:29108> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/266> ;
        wp:bdbHmdb          <https://identifiers.org/hmdb/HMDB0000464> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/BHPQYMZQTOCNFJ-UHFFFAOYSA-N> ;
        wp:bdbKeggCompound  <https://identifiers.org/kegg.compound/C00076> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID271> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q23905776> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4838_r140111/DataNode/c458d> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/DataNode/e8343> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/DataNode/a69c1> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/DataNode/c68aa> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/DataNode/c8ba8> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/DataNode/e3f3d> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/DataNode/f4f3e> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/DataNode/da70b> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/DataNode/e9142> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/DataNode/ac41e> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/DataNode/d0f53> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/DataNode/e5c77> ;
        foaf:page           <https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:29108> .

<http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id8f21ab6e>
        rdf:type          wp:Conversion , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4838_r140111> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4838_r140111/Interaction/id8f21ab6e> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000100030> , <https://identifiers.org/uniprot/Q01986> ;
        wp:source         <https://identifiers.org/uniprot/Q01986> ;
        wp:target         <https://identifiers.org/ensembl/ENSG00000100030> .

<http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id1e5bb836>
        rdf:type          wp:Stimulation , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4838_r140111> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4838_r140111/Interaction/id1e5bb836> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000157764> , <https://identifiers.org/uniprot/Q5U0Q1> ;
        wp:source         <https://identifiers.org/uniprot/Q5U0Q1> ;
        wp:target         <https://identifiers.org/ensembl/ENSG00000157764> .

<http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id6c3f20fd>
        rdf:type          wp:Binding , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4838_r140111> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4838_r140111/Interaction/id6c3f20fd> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000120868> , <https://identifiers.org/chebi/CHEBI:18070> ;
        wp:source         <https://identifiers.org/chebi/CHEBI:18070> ;
        wp:target         <https://identifiers.org/ensembl/ENSG00000120868> .

<http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id5443ab72>
        rdf:type          wp:Binding , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4838_r140111> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4838_r140111/Interaction/id5443ab72> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000067182> , <https://identifiers.org/uniprot/P16599> ;
        wp:source         <https://identifiers.org/uniprot/P16599> ;
        wp:target         <https://identifiers.org/ensembl/ENSG00000067182> .

<http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/idb91bb510>
        rdf:type          wp:Stimulation , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4838_r140111> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4838_r140111/Interaction/idb91bb510> ;
        wp:participants   <https://identifiers.org/uniprot/P49187> , <https://identifiers.org/chebi/CHEBI:26523> ;
        wp:source         <https://identifiers.org/chebi/CHEBI:26523> ;
        wp:target         <https://identifiers.org/uniprot/P49187> .

<http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id6c69329e>
        rdf:type          wp:Stimulation , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4838_r140111> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4838_r140111/Interaction/id6c69329e> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000107796> , <https://identifiers.org/ensembl/ENSG00000141646> ;
        wp:source         <https://identifiers.org/ensembl/ENSG00000141646> ;
        wp:target         <https://identifiers.org/ensembl/ENSG00000107796> .

<http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id9e2690f7>
        rdf:type          wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4838_r140111> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4838_r140111/Interaction/id9e2690f7> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000221823> .

<http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id5631c029>
        rdf:type          wp:Binding , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4838_r140111> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4838_r140111/Interaction/id5631c029> ;
        wp:participants   <https://identifiers.org/uniprot/P22199> , <https://identifiers.org/chebi/CHEBI:27584> ;
        wp:source         <https://identifiers.org/chebi/CHEBI:27584> ;
        wp:target         <https://identifiers.org/uniprot/P22199> .

<http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id1144e5c1>
        rdf:type          wp:Stimulation , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4838_r140111> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4838_r140111/Interaction/id1144e5c1> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000175387> , <https://identifiers.org/uniprot/Q15493> ;
        wp:source         <https://identifiers.org/uniprot/Q15493> ;
        wp:target         <https://identifiers.org/ensembl/ENSG00000175387> .

<https://identifiers.org/uniprot/P16599>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "TNFA" ;
        dc:identifier       <https://identifiers.org/uniprot/P16599> ;
        dc:source           "UniProtKB" ;
        dcterms:identifier  "P16599" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id5443ab72> , <https://identifiers.org/wikipathways/WP4838_r140111> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSRNOG00000070745> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/24835> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A8L2URC2> , <https://identifiers.org/uniprot/P16599> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4838_r140111/DataNode/b69e9> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P16599> , <http://purl.uniprot.org/uniprot/A0A8L2URC2> ;
        foaf:page           <http://www.uniprot.org/uniprot/P16599> .

<https://identifiers.org/wikipathways/WP4838>
        pav:hasVersion  <https://identifiers.org/wikipathways/WP4838_r140111> .

<https://identifiers.org/ensembl/ENSG00000087088>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "BAX" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000087088> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000087088" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/iddb2136ed> , <https://identifiers.org/wikipathways/WP4838_r140111> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000087088> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/581> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/BAX> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/H0YA56> , <https://identifiers.org/uniprot/I6LPK7> , <https://identifiers.org/uniprot/Q07812> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q14905392> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4838_r140111/DataNode/a34b5> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/H0YA56> , <http://purl.uniprot.org/uniprot/Q07812> , <http://purl.uniprot.org/uniprot/I6LPK7> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000087088> .

<http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/ide77a5673>
        rdf:type          wp:Binding , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4838_r140111> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4838_r140111/Interaction/ide77a5673> ;
        wp:participants   <https://identifiers.org/uniprot/Q64568> , <https://identifiers.org/uniprot/Q15493> ;
        wp:source         <https://identifiers.org/uniprot/Q15493> ;
        wp:target         <https://identifiers.org/uniprot/Q64568> .

<http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id334a79e6>
        rdf:type          wp:Stimulation , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4838_r140111> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4838_r140111/Interaction/id334a79e6> ;
        wp:participants   <https://identifiers.org/uniprot/Q8NE86> , <https://identifiers.org/uniprot/Q15493> ;
        wp:source         <https://identifiers.org/uniprot/Q15493> ;
        wp:target         <https://identifiers.org/uniprot/Q8NE86> .

<http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id888eb0e3>
        rdf:type          wp:Stimulation , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4838_r140111> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4838_r140111/Interaction/id888eb0e3> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000120659> , <https://identifiers.org/uniprot/Q15493> ;
        wp:source         <https://identifiers.org/uniprot/Q15493> ;
        wp:target         <https://identifiers.org/ensembl/ENSG00000120659> .

<http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/idb8513fd8>
        rdf:type          wp:Stimulation , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4838_r140111> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4838_r140111/Interaction/idb8513fd8> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000175387> , <https://identifiers.org/uniprot/P36897> ;
        wp:source         <https://identifiers.org/uniprot/P36897> ;
        wp:target         <https://identifiers.org/ensembl/ENSG00000175387> .

<https://identifiers.org/chebi/CHEBI:16595>
        rdf:type            wp:Metabolite , wp:DataNode ;
        rdfs:label          "IP3" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/MMWCIQZXVOZEGG-XJTPDSDZSA-N> ;
        dc:identifier       <https://identifiers.org/chebi/CHEBI:16595> ;
        dc:source           "ChEBI" ;
        dcterms:identifier  "CHEBI:16595" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id6611bc0c> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/idf46e9608> , <https://identifiers.org/wikipathways/WP4838_r140111> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id2ea7d1b6> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id465985a4> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:16595> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/388562> ;
        wp:bdbHmdb          <https://identifiers.org/hmdb/HMDB0001498> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/MMWCIQZXVOZEGG-XJTPDSDZSA-N> ;
        wp:bdbKeggCompound  <https://identifiers.org/kegg.compound/C01245> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID439456> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q26998374> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4838_r140111/DataNode/b593c> ;
        foaf:page           <https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:16595> .

<https://identifiers.org/chebi/CHEBI:16027>
        rdf:type            wp:Metabolite , wp:DataNode ;
        rdfs:label          "AMP" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/UDMBCSSLTHHNCD-KQYNXXCUSA-N> ;
        dc:identifier       <https://identifiers.org/chebi/CHEBI:16027> ;
        dc:source           "ChEBI" ;
        dcterms:identifier  "CHEBI:16027" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/idf08db64b> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id93599b57> , <https://identifiers.org/wikipathways/WP4838_r140111> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:16027> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/5858> ;
        wp:bdbHmdb          <https://identifiers.org/hmdb/HMDB0000045> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/UDMBCSSLTHHNCD-KQYNXXCUSA-N> ;
        wp:bdbKeggCompound  <https://identifiers.org/kegg.compound/C00020> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID6083> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q90529152> , <http://www.wikidata.org/entity/Q318369> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4838_r140111/DataNode/c3c2a> ;
        foaf:page           <https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:16027> .

<http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/iddb2136ed>
        rdf:type          wp:Stimulation , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4838_r140111> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4838_r140111/Interaction/iddb2136ed> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000030110> , <https://identifiers.org/ensembl/ENSG00000087088> ;
        wp:source         <https://identifiers.org/ensembl/ENSG00000087088> ;
        wp:target         <https://identifiers.org/ensembl/ENSG00000030110> .

<http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id87ee02a2>
        rdf:type          wp:Stimulation , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4838_r140111> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4838_r140111/Interaction/id87ee02a2> ;
        wp:participants   <https://identifiers.org/chebi/CHEBI:133022> ;
        wp:source         <https://identifiers.org/chebi/CHEBI:133022> ;
        wp:target         <https://identifiers.org/chebi/CHEBI:133022> .

<https://identifiers.org/ensembl/ENSG00000120868>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "APAF1" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000120868> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000120868" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/idd64e7382> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id6c3f20fd> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/idde2e76fc> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id7c10121f> , <https://identifiers.org/wikipathways/WP4838_r140111> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000120868> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/317> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/APAF1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/O14727> , <https://identifiers.org/uniprot/C9JLV4> , <https://identifiers.org/uniprot/F8VNZ0> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q17829004> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4838_r140111/DataNode/f017c> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/O14727> , <http://purl.uniprot.org/uniprot/C9JLV4> , <http://purl.uniprot.org/uniprot/F8VNZ0> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000120868> .

<https://identifiers.org/ensembl/ENSG00000221823>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "PPP3R1" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000221823> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000221823" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/idc2741289> , <https://identifiers.org/wikipathways/WP4838_r140111> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id9e2690f7> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id47c085b3> ;
        dcterms:references  <https://identifiers.org/pubmed/19536897> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000221823> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/5534> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/PPP3R1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/P63098> , <https://identifiers.org/uniprot/D3YTA9> , <https://identifiers.org/uniprot/F6U1T9> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18030734> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4838_r140111/DataNode/ae248> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/DataNode/dc256> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/D3YTA9> , <http://purl.uniprot.org/uniprot/F6U1T9> , <http://purl.uniprot.org/uniprot/P63098> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000221823> .

<https://identifiers.org/uniprot/A0A087X0I9>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "PRKCQ" ;
        dc:identifier       <https://identifiers.org/uniprot/A0A087X0I9> ;
        dc:source           "UniProtKB" ;
        dcterms:identifier  "A0A087X0I9" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id6b58dd77> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/idf083ef71> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/ide231f86c> , <https://identifiers.org/wikipathways/WP4838_r140111> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id3233e920> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id4d903a10> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/ida0a35855> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id48a5596_1> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id48a5596_2> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A087X0I9> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4838_r140111/DataNode/cd532> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A087X0I9> ;
        foaf:page           <http://www.uniprot.org/uniprot/A0A087X0I9> .

<https://identifiers.org/chebi/CHEBI:3324>
        rdf:type            wp:Metabolite , wp:DataNode ;
        rdfs:label          "Calmodulin" ;
        dc:identifier       <https://identifiers.org/chebi/CHEBI:3324> ;
        dc:source           "ChEBI" ;
        dcterms:identifier  "CHEBI:3324" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4838_r140111> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/ide62d4df> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/Complex/eeb78> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:3324> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q409145> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4838_r140111/DataNode/ec744> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/DataNode/d7cf7> ;
        foaf:page           <https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:3324> .

<http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id4d48de2b>
        rdf:type          wp:Stimulation , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4838_r140111> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4838_r140111/Interaction/id4d48de2b> ;
        wp:participants   <https://identifiers.org/chebi/CHEBI:26523> , <https://identifiers.org/chebi/CHEBI:70982> ;
        wp:source         <https://identifiers.org/chebi/CHEBI:70982> ;
        wp:target         <https://identifiers.org/chebi/CHEBI:26523> .

<http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/idf0f1428>
        rdf:type          wp:Conversion , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4838_r140111> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4838_r140111/Interaction/idf0f1428> ;
        wp:participants   <https://identifiers.org/chebi/CHEBI:16480> , <https://identifiers.org/chebi/CHEBI:32682> ;
        wp:source         <https://identifiers.org/chebi/CHEBI:32682> ;
        wp:target         <https://identifiers.org/chebi/CHEBI:16480> .

<http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id4b1ff947>
        rdf:type          wp:Stimulation , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4838_r140111> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4838_r140111/Interaction/id4b1ff947> ;
        wp:participants   <https://identifiers.org/uniprot/P49187> , <https://identifiers.org/ensembl/ENSG00000100030> ;
        wp:source         <https://identifiers.org/ensembl/ENSG00000100030> ;
        wp:target         <https://identifiers.org/uniprot/P49187> .

<http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id2ad47f71>
        rdf:type          wp:Stimulation , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4838_r140111> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4838_r140111/Interaction/id2ad47f71> ;
        wp:participants   <https://identifiers.org/chebi/CHEBI:133022> , <https://identifiers.org/uniprot/Q15493> ;
        wp:source         <https://identifiers.org/uniprot/Q15493> ;
        wp:target         <https://identifiers.org/chebi/CHEBI:133022> .

<https://identifiers.org/uniprot/Q01728>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "SLC8A1" ;
        dc:identifier       <https://identifiers.org/uniprot/Q01728> ;
        dc:source           "UniProtKB" ;
        dcterms:identifier  "Q01728" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4838_r140111> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSRNOG00000008479> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/29715> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q01728> , <https://identifiers.org/uniprot/M0R3V7> , <https://identifiers.org/uniprot/A0A8L2QNY8> , <https://identifiers.org/uniprot/A0A8I5ZXH4> , <https://identifiers.org/uniprot/A0A8I6AXH4> , <https://identifiers.org/uniprot/A0A8I5XVV7> , <https://identifiers.org/uniprot/A0A8L2QK59> , <https://identifiers.org/uniprot/A0A8L2QKS1> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4838_r140111/DataNode/ca957> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q01728> , <http://purl.uniprot.org/uniprot/A0A8L2QNY8> , <http://purl.uniprot.org/uniprot/A0A8L2QKS1> , <http://purl.uniprot.org/uniprot/A0A8I6AXH4> , <http://purl.uniprot.org/uniprot/A0A8I5XVV7> , <http://purl.uniprot.org/uniprot/A0A8L2QK59> , <http://purl.uniprot.org/uniprot/A0A8I5ZXH4> , <http://purl.uniprot.org/uniprot/M0R3V7> ;
        foaf:page           <http://www.uniprot.org/uniprot/Q01728> .

<http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id6611bc0c>
        rdf:type          wp:Stimulation , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4838_r140111> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4838_r140111/Interaction/id6611bc0c> ;
        wp:participants   <https://identifiers.org/chebi/CHEBI:16595> , <https://identifiers.org/chebi/CHEBI:18348> ;
        wp:source         <https://identifiers.org/chebi/CHEBI:18348> ;
        wp:target         <https://identifiers.org/chebi/CHEBI:16595> .

<https://identifiers.org/wikidata/Q421212>
        rdf:type            wp:DataNode , wp:Metabolite ;
        rdfs:label          "Lanthanum chloride" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/ICAKDTKJOYSXGC-UHFFFAOYSA-N> ;
        dc:identifier       <https://identifiers.org/wikidata/Q421212> ;
        dc:source           "Wikidata" ;
        dcterms:identifier  "Q421212" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4838_r140111> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:231515> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/58275> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/ICAKDTKJOYSXGC-UHFFFAOYSA-K> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID64735> , <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID9859665> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q421212> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4838_r140111/DataNode/e87a8> ;
        foaf:page           <https://scholia.toolforge.org/Q421212> .

<https://identifiers.org/chebi/CHEBI:133022>
        rdf:type            wp:DataNode , wp:Metabolite ;
        rdfs:label          "Bcl-2" ;
        dc:identifier       <https://identifiers.org/chebi/CHEBI:133022> ;
        dc:source           "ChEBI" ;
        dcterms:identifier  "CHEBI:133022" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/ida89e6341> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id2ad47f71> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id87ee02a2> , <https://identifiers.org/wikipathways/WP4838_r140111> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id13a4077d> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:133022> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4838_r140111/DataNode/ac819> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/DataNode/af9e7> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/DataNode/d6e63> ;
        foaf:page           <https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:133022> .

<https://identifiers.org/uniprot/Q8NE86>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "MCU" ;
        dc:identifier       <https://identifiers.org/uniprot/Q8NE86> ;
        dc:source           "UniProtKB" ;
        dcterms:identifier  "Q8NE86" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id334a79e6> , <https://identifiers.org/wikipathways/WP4838_r140111> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/idf46e9608> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id7731baa4> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/ide62d4df> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000156026> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/90550> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/MCU> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/S4R332> , <https://identifiers.org/uniprot/S4R319> , <https://identifiers.org/uniprot/S4R3F5> , <https://identifiers.org/uniprot/Q8NE86> , <https://identifiers.org/uniprot/S4R468> , <https://identifiers.org/uniprot/S4R3W8> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4838_r140111/DataNode/cbd7b> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/DataNode/ef204> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/DataNode/ee37d> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/S4R3F5> , <http://purl.uniprot.org/uniprot/S4R468> , <http://purl.uniprot.org/uniprot/S4R332> , <http://purl.uniprot.org/uniprot/Q8NE86> , <http://purl.uniprot.org/uniprot/S4R3W8> , <http://purl.uniprot.org/uniprot/S4R319> ;
        foaf:page           <http://www.uniprot.org/uniprot/Q8NE86> .

<http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/idec4a322d>
        rdf:type          wp:Inhibition , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4838_r140111> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4838_r140111/Interaction/idec4a322d> ;
        wp:participants   <https://identifiers.org/uniprot/B3VK56> , <https://identifiers.org/uniprot/Q15493> ;
        wp:source         <https://identifiers.org/uniprot/Q15493> ;
        wp:target         <https://identifiers.org/uniprot/B3VK56> .

<http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/idf46e9608>
        rdf:type          wp:Inhibition , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4838_r140111> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4838_r140111/Interaction/idf46e9608> ;
        wp:participants   <https://identifiers.org/uniprot/Q8NE86> , <https://identifiers.org/chebi/CHEBI:16595> ;
        wp:source         <https://identifiers.org/chebi/CHEBI:16595> ;
        wp:target         <https://identifiers.org/uniprot/Q8NE86> .

<http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/ida89e6341>
        rdf:type          wp:Inhibition , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4838_r140111> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4838_r140111/Interaction/ida89e6341> ;
        wp:participants   <https://identifiers.org/chebi/CHEBI:133022> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id2c8985aa> ;
        wp:source         <https://identifiers.org/chebi/CHEBI:133022> ;
        wp:target         <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id2c8985aa> .

<https://identifiers.org/uniprot/P97526>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "NF1" ;
        dc:identifier       <https://identifiers.org/uniprot/P97526> ;
        dc:source           "UniProtKB" ;
        dcterms:identifier  "P97526" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id1599595e> , <https://identifiers.org/wikipathways/WP4838_r140111> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/P97526> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4838_r140111/DataNode/d59a7> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P97526> ;
        foaf:page           <http://www.uniprot.org/uniprot/P97526> .

<http://rdf.wikipathways.org/Pathway/WP4838_r140111/ComplexBinding/eeb78>
        rdf:type          wp:ComplexBinding , wp:Binding , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4838_r140111> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4838_r140111/Group/eeb78> ;
        wp:participants   <https://identifiers.org/chebi/CHEBI:29108> , <https://identifiers.org/chebi/CHEBI:3324> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/Complex/eeb78> .

<http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/idb002d12f>
        rdf:type          wp:Stimulation , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4838_r140111> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4838_r140111/Interaction/idb002d12f> ;
        wp:participants   <https://identifiers.org/chebi/CHEBI:29108> , <https://identifiers.org/uniprot/P27791> ;
        wp:source         <https://identifiers.org/uniprot/P27791> ;
        wp:target         <https://identifiers.org/chebi/CHEBI:29108> .

<http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id6d323aed>
        rdf:type          wp:Binding , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4838_r140111> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4838_r140111/Interaction/id6d323aed> ;
        wp:participants   <https://identifiers.org/uniprot/A0A0K0PUW7> , <https://identifiers.org/uniprot/P01258> ;
        wp:source         <https://identifiers.org/uniprot/P01258> ;
        wp:target         <https://identifiers.org/uniprot/A0A0K0PUW7> .

<https://identifiers.org/chebi/CHEBI:31991>
        rdf:type            wp:Metabolite , wp:DataNode ;
        rdfs:label          "PSP" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/BELBBZDIHDAJOR-UHFFFAOYSA-N> ;
        dc:identifier       <https://identifiers.org/chebi/CHEBI:31991> ;
        dc:source           "ChEBI" ;
        dcterms:identifier  "CHEBI:31991" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4838_r140111> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id90b65c6> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id6b58dd77> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id8a1f053e> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:31991> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/4602> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/BELBBZDIHDAJOR-UHFFFAOYSA-N> ;
        wp:bdbKeggCompound  <https://identifiers.org/kegg.compound/C12600> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID4766> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q418719> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4838_r140111/DataNode/bca76> ;
        foaf:page           <https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:31991> .

<https://identifiers.org/uniprot/Q99683>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "MAP3K5" ;
        dc:identifier       <https://identifiers.org/uniprot/Q99683> ;
        dc:source           "UniProtKB" ;
        dcterms:identifier  "Q99683" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4838_r140111> , <http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/iddcb5cced> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000197442> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/4217> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/MAP3K5> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q99683> , <https://identifiers.org/uniprot/A0A8V8TMH5> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4838_r140111/DataNode/d99c3> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A8V8TMH5> , <http://purl.uniprot.org/uniprot/Q99683> ;
        foaf:page           <http://www.uniprot.org/uniprot/Q99683> .

<http://rdf.wikipathways.org/Pathway/WP4838_r140111/WP/Interaction/id9e167b65>
        rdf:type          wp:Stimulation , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4838_r140111> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4838_r140111/Interaction/id9e167b65> ;
        wp:participants   <https://identifiers.org/uniprot/KW-0788> , <https://identifiers.org/uniprot/Q15493> ;
        wp:source         <https://identifiers.org/uniprot/Q15493> ;
        wp:target         <https://identifiers.org/uniprot/KW-0788> .

<https://identifiers.org/pubmed/26398287>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "26398287" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4838_r140111> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/26398287> .
