@prefix biopax:  <http://www.biopax.org/release/biopax-level3.owl#> .
@prefix cito:    <http://purl.org/spar/cito/> .
@prefix dc:      <http://purl.org/dc/elements/1.1/> .
@prefix dcterms: <http://purl.org/dc/terms/> .
@prefix foaf:    <http://xmlns.com/foaf/0.1/> .
@prefix freq:    <http://purl.org/cld/freq/> .
@prefix gpml:    <http://vocabularies.wikipathways.org/gpml#> .
@prefix obo:     <http://purl.obolibrary.org/obo/> .
@prefix owl:     <http://www.w3.org/2002/07/owl#> .
@prefix pav:     <http://purl.org/pav/> .
@prefix prov:    <http://www.w3.org/ns/prov#> .
@prefix rdf:     <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix rdfs:    <http://www.w3.org/2000/01/rdf-schema#> .
@prefix skos:    <http://www.w3.org/2004/02/skos/core#> .
@prefix void:    <http://rdfs.org/ns/void#> .
@prefix wp:      <http://vocabularies.wikipathways.org/wp#> .
@prefix wprdf:   <http://rdf.wikipathways.org/> .
@prefix xsd:     <http://www.w3.org/2001/XMLSchema#> .

<https://identifiers.org/pubmed/25012593>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "25012593" ;
        dcterms:isPartOf    <https://identifiers.org/ensembl/ENSG00000112062> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/25012593> .

<http://rdf.wikipathways.org/Pathway/WP4919_r140179/Complex/d7b37>
        rdf:type          wp:Complex , wp:DataNode ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4919_r140179> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4919_r140179/Group/d7b37> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000173039> , <https://identifiers.org/ensembl/ENSG00000138303> .

<https://identifiers.org/ensembl/ENSG00000107643>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "JNK" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000107643> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000107643" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4919_r140179> , <http://rdf.wikipathways.org/Pathway/WP4919_r140179/WP/Interaction/id97c0df21> , <http://rdf.wikipathways.org/Pathway/WP4919_r140179/WP/Interaction/id62e9aeab> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000107643> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/5599> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/MAPK8> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A3B3IRW7> , <https://identifiers.org/uniprot/A1L4K2> , <https://identifiers.org/uniprot/C9JWQ4> , <https://identifiers.org/uniprot/P45983> , <https://identifiers.org/uniprot/C9J762> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18255755> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4919_r140179/DataNode/a6222> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A1L4K2> , <http://purl.uniprot.org/uniprot/A0A3B3IRW7> , <http://purl.uniprot.org/uniprot/C9JWQ4> , <http://purl.uniprot.org/uniprot/P45983> , <http://purl.uniprot.org/uniprot/C9J762> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000107643> .

<https://identifiers.org/hgnc/391>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "AKT" ;
        dc:identifier       <https://identifiers.org/hgnc/391> ;
        dc:source           "HGNC Accession number" ;
        dcterms:identifier  "391" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4919_r140179> , <http://rdf.wikipathways.org/Pathway/WP4919_r140179/WP/Interaction/id7eed551e> , <http://rdf.wikipathways.org/Pathway/WP4919_r140179/WP/Interaction/id92efa4bc> , <http://rdf.wikipathways.org/Pathway/WP4919_r140179/WP/Interaction/id31ec123d> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4919_r140179/DataNode/cb9ac> ;
        foaf:page           <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/391> .

<http://rdf.wikipathways.org/Pathway/WP4919_r140179/Complex/b244b>
        rdf:type          wp:Complex , wp:DataNode ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4919_r140179> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4919_r140179/Group/b244b> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000173039> .

<https://identifiers.org/chebi/CHEBI:15377>
        rdf:type            wp:Metabolite , wp:DataNode ;
        rdfs:label          "H₂O" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/XLYOFNOQVPJJNP-UHFFFAOYSA-N> ;
        dc:identifier       <https://identifiers.org/chebi/CHEBI:15377> ;
        dc:source           "ChEBI" ;
        dcterms:identifier  "CHEBI:15377" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4919_r140179/WP/Interaction/id18d738b2> , <https://identifiers.org/wikipathways/WP4919_r140179> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:15377> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/937> ;
        wp:bdbHmdb          <https://identifiers.org/hmdb/HMDB0002111> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/XLYOFNOQVPJJNP-UHFFFAOYSA-N> ;
        wp:bdbKeggCompound  <https://identifiers.org/kegg.compound/C00001> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID962> , <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID22247451> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q283> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4919_r140179/DataNode/fd31f> ;
        foaf:page           <https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:15377> .

<http://rdf.wikipathways.org/Pathway/WP4919_r140179/WP/Interaction/id62e9aeab>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4919_r140179> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4919_r140179/Interaction/id62e9aeab> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000107643> , <https://identifiers.org/ensembl/ENSG00000136869> ;
        wp:source         <https://identifiers.org/ensembl/ENSG00000136869> ;
        wp:target         <https://identifiers.org/ensembl/ENSG00000107643> .

<https://identifiers.org/ensembl/ENSG00000136869>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "TLR4" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000136869> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000136869" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4919_r140179/WP/Interaction/id62e9aeab> , <https://identifiers.org/wikipathways/WP4919_r140179> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000136869> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/7099> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/TLR4> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A2R8Y7P4> , <https://identifiers.org/uniprot/O00206> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q14914098> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4919_r140179/DataNode/fc494> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/O00206> , <http://purl.uniprot.org/uniprot/A0A2R8Y7P4> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000136869> .

<http://rdf.wikipathways.org/Pathway/WP4919_r140179/WP/Interaction/id7eed551e>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4919_r140179> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4919_r140179/Interaction/id7eed551e> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000213341> , <https://identifiers.org/hgnc/391> ;
        wp:source         <https://identifiers.org/hgnc/391> ;
        wp:target         <https://identifiers.org/ensembl/ENSG00000213341> .

<https://identifiers.org/ensembl/ENSG00000173039>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "p65" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000173039> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000173039" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4919_r140179/Complex/d7b37> , <http://rdf.wikipathways.org/Pathway/WP4919_r140179/Complex/b244b> , <https://identifiers.org/wikipathways/WP4919_r140179> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000173039> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/5970> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/RELA> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/E9PJZ9> , <https://identifiers.org/uniprot/E9PJR1> , <https://identifiers.org/uniprot/Q2TAM5> , <https://identifiers.org/uniprot/E9PRX2> , <https://identifiers.org/uniprot/H0YCB4> , <https://identifiers.org/uniprot/Q04206> , <https://identifiers.org/uniprot/E9PKV4> , <https://identifiers.org/uniprot/E9PKH5> , <https://identifiers.org/uniprot/E9PSE4> , <https://identifiers.org/uniprot/E9PNV4> , <https://identifiers.org/uniprot/E9PNK5> , <https://identifiers.org/uniprot/A0A087X0W8> , <https://identifiers.org/uniprot/E9PMD5> , <https://identifiers.org/uniprot/E9PM47> , <https://identifiers.org/uniprot/E9PI38> , <https://identifiers.org/uniprot/E9PQS6> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q15326052> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4919_r140179/DataNode/f8b71> , <http://rdf.wikipathways.org/Pathway/WP4919_r140179/DataNode/f6d9f> , <http://rdf.wikipathways.org/Pathway/WP4919_r140179/DataNode/b501c> , <http://rdf.wikipathways.org/Pathway/WP4919_r140179/DataNode/af4a8> , <http://rdf.wikipathways.org/Pathway/WP4919_r140179/DataNode/d8666> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/E9PM47> , <http://purl.uniprot.org/uniprot/E9PNV4> , <http://purl.uniprot.org/uniprot/A0A087X0W8> , <http://purl.uniprot.org/uniprot/E9PI38> , <http://purl.uniprot.org/uniprot/E9PNK5> , <http://purl.uniprot.org/uniprot/E9PJZ9> , <http://purl.uniprot.org/uniprot/E9PKH5> , <http://purl.uniprot.org/uniprot/E9PKV4> , <http://purl.uniprot.org/uniprot/H0YCB4> , <http://purl.uniprot.org/uniprot/E9PMD5> , <http://purl.uniprot.org/uniprot/E9PQS6> , <http://purl.uniprot.org/uniprot/E9PRX2> , <http://purl.uniprot.org/uniprot/Q2TAM5> , <http://purl.uniprot.org/uniprot/Q04206> , <http://purl.uniprot.org/uniprot/E9PJR1> , <http://purl.uniprot.org/uniprot/E9PSE4> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000173039> .

<https://identifiers.org/ensembl/ENSG00000112062>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "MAPK14" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000112062> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000112062" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4919_r140179/WP/Interaction/id31ec123d> , <https://identifiers.org/wikipathways/WP4919_r140179> , <http://rdf.wikipathways.org/Pathway/WP4919_r140179/WP/Interaction/id3f672228> ;
        dcterms:references  <https://identifiers.org/pubmed/25012593> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000112062> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/1432> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/MAPK14> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/E7EX54> , <https://identifiers.org/uniprot/L7RSM2> , <https://identifiers.org/uniprot/H7C4E2> , <https://identifiers.org/uniprot/B5TY33> , <https://identifiers.org/uniprot/B4E0K5> , <https://identifiers.org/uniprot/A0A024RD15> , <https://identifiers.org/uniprot/Q16539> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q15326910> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4919_r140179/DataNode/ccafd> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/B5TY33> , <http://purl.uniprot.org/uniprot/A0A024RD15> , <http://purl.uniprot.org/uniprot/E7EX54> , <http://purl.uniprot.org/uniprot/H7C4E2> , <http://purl.uniprot.org/uniprot/Q16539> , <http://purl.uniprot.org/uniprot/B4E0K5> , <http://purl.uniprot.org/uniprot/L7RSM2> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000112062> .

<https://identifiers.org/homologene/481>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "IL-1B" ;
        dc:identifier       <https://identifiers.org/homologene/481> ;
        dc:source           "HomoloGene" ;
        dcterms:identifier  "481" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4919_r140179> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4919_r140179/DataNode/abe6a> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/homologene/481> .

<https://identifiers.org/chebi/CHEBI:16301>
        rdf:type            wp:Metabolite , wp:DataNode ;
        rdfs:label          "Nitrite" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/IOVCWXUNBOPUCH-UHFFFAOYSA-N> ;
        dc:identifier       <https://identifiers.org/chebi/CHEBI:16301> ;
        dc:source           "ChEBI" ;
        dcterms:identifier  "CHEBI:16301" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4919_r140179> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:16301> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/921> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/IOVCWXUNBOPUCH-UHFFFAOYSA-M> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID946> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q213788> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4919_r140179/DataNode/e23ab> ;
        foaf:page           <https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:16301> .

<http://rdf.wikipathways.org/Pathway/WP4919_r140179/Complex/ac2fe>
        rdf:type          wp:Complex , wp:DataNode ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4919_r140179> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4919_r140179/Group/ac2fe> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000170345> , <https://identifiers.org/ensembl/ENSG00000177606> .

<https://identifiers.org/interpro/IPR000403>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "PI3K" ;
        dc:identifier       <https://identifiers.org/interpro/IPR000403> ;
        dc:source           "InterPro" ;
        dcterms:identifier  "IPR000403" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4919_r140179> , <http://rdf.wikipathways.org/Pathway/WP4919_r140179/WP/Interaction/id92efa4bc> , <http://rdf.wikipathways.org/Pathway/WP4919_r140179/WP/Interaction/idcf712c1e> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4919_r140179/DataNode/d7441> ;
        foaf:page           <https://www.ebi.ac.uk/interpro/entry/InterPro/IPR000403> .

<https://identifiers.org/ensembl/ENSG00000007171>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "iNOS" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000007171> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000007171" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4919_r140179/WP/Interaction/id3f672228> , <https://identifiers.org/wikipathways/WP4919_r140179> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000007171> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/4843> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/NOS2> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A2R8YDS4> , <https://identifiers.org/uniprot/A0A8V8TKZ7> , <https://identifiers.org/uniprot/A0A8V8TLB1> , <https://identifiers.org/uniprot/A0A8V8TMI7> , <https://identifiers.org/uniprot/A0A8V8TKX9> , <https://identifiers.org/uniprot/P35228> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18030178> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4919_r140179/DataNode/d9d7d> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A8V8TLB1> , <http://purl.uniprot.org/uniprot/A0A8V8TKZ7> , <http://purl.uniprot.org/uniprot/A0A2R8YDS4> , <http://purl.uniprot.org/uniprot/A0A8V8TMI7> , <http://purl.uniprot.org/uniprot/A0A8V8TKX9> , <http://purl.uniprot.org/uniprot/P35228> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000007171> .

<http://rdf.wikipathways.org/Pathway/WP4919_r140179/WP/Interaction/id7743c6c2>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4919_r140179> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4919_r140179/Interaction/id7743c6c2> , <http://rdf.wikipathways.org/Pathway/WP4919_r140179/Interaction/id2f9a0bd0> ;
        wp:participants   <https://identifiers.org/chebi/CHEBI:15379> , <https://identifiers.org/chebi/CHEBI:16480> , <https://identifiers.org/chebi/CHEBI:48107> ;
        wp:source         <https://identifiers.org/chebi/CHEBI:16480> ;
        wp:target         <https://identifiers.org/chebi/CHEBI:48107> , <https://identifiers.org/chebi/CHEBI:15379> .

<http://rdf.wikipathways.org/Pathway/WP4919_r140179/ComplexBinding/a8ff1>
        rdf:type          wp:ComplexBinding , wp:Binding , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4919_r140179> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4919_r140179/Group/a8ff1> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000138303> , <http://rdf.wikipathways.org/Pathway/WP4919_r140179/Complex/a8ff1> .

<http://rdf.wikipathways.org/Pathway/WP4919_r140179/WP/Interaction/idc4dcb1f4>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4919_r140179> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4919_r140179/Interaction/idc4dcb1f4> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000213341> , <https://identifiers.org/ensembl/ENSG00000198793> ;
        wp:source         <https://identifiers.org/ensembl/ENSG00000198793> ;
        wp:target         <https://identifiers.org/ensembl/ENSG00000213341> .

<http://rdf.wikipathways.org/Pathway/WP4919_r140179/WP/Interaction/idcf712c1e>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4919_r140179> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4919_r140179/Interaction/idcf712c1e> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000198793> , <https://identifiers.org/interpro/IPR000403> ;
        wp:source         <https://identifiers.org/interpro/IPR000403> ;
        wp:target         <https://identifiers.org/ensembl/ENSG00000198793> .

<https://identifiers.org/chebi/CHEBI:16467>
        rdf:type            wp:Metabolite , wp:DataNode ;
        rdfs:label          "L-arginine" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/ODKSFYDXXFIFQN-BYPYZUCNSA-N> ;
        dc:identifier       <https://identifiers.org/chebi/CHEBI:16467> ;
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        foaf:page           <https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:16467> .

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        foaf:page           <https://www.ensembl.org/id/ENSG00000198804> .

obo:NCBITaxon_9606  obo:NCIT_C179773  "9606" .

<https://identifiers.org/wikipathways/WP4919>
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<https://identifiers.org/pubmed/27412492>
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        wp:participants   <https://identifiers.org/ensembl/ENSG00000173039> , <http://rdf.wikipathways.org/Pathway/WP4919_r140179/Complex/b244b> .

<https://identifiers.org/ensembl/ENSG00000198793>
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<https://identifiers.org/wikipathways/WP3941>
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<https://doi.org/10.1016%2Fj.humgen.2022.201135>
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        dc:identifier       <https://identifiers.org/chebi/CHEBI:15379> ;
        dc:source           "ChEBI" ;
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        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID977> ;
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        foaf:page           <https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:15379> .

<http://rdf.wikipathways.org/Pathway/WP4919_r140179/ComplexBinding/ac2fe>
        rdf:type          wp:ComplexBinding , wp:Binding , wp:Interaction ;
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        rdf:type        foaf:Image ;
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<http://rdf.wikipathways.org/Pathway/WP4919_r140179/Complex/a8ff1>
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        wp:participants   <https://identifiers.org/ensembl/ENSG00000138303> .

<https://identifiers.org/chebi/CHEBI:29108>
        rdf:type            wp:DataNode , wp:Metabolite ;
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        dc:identifier       <https://identifiers.org/chebi/CHEBI:29108> ;
        dc:source           "ChEBI" ;
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        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:29108> ;
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        foaf:page           <https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:29108> .

<https://identifiers.org/wikipathways/WP4919_r140179>
        rdf:type                wp:Pathway , skos:Collection ;
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        dc:source               "WikiPathways" ;
        dc:title                "Neuroinflammation"@en ;
        dcterms:description     "Neuroinflammation is inflammation specific to parts of the central nervous system. It can be triggered by external or internal factors, such as UV damage, inflammatory cytokines and oxidative stress. Stress on the cell leads to activation of inflammatory response pathways that involve several transcription factors such as AP-1 and NFkB, which will lead to the transcription of several proteins and/or cytokines." ;
        dcterms:identifier      "WP4919" ;
        dcterms:references      <https://identifiers.org/pubmed/27412492> ;
        cito:cites              <https://identifiers.org/pubmed/25012593> , <https://identifiers.org/pubmed/27412492> ;
        wp:cellTypeOntologyTag  obo:CL_0000540 ;
        wp:isAbout              <http://rdf.wikipathways.org/Pathway/WP4919_r140179> ;
        wp:ontologyTag          wp:Curation:AnalysisCollection , obo:PW_0000003 , obo:PW_0001251 , wp:Curation:ONTOX , obo:PW_0000237 , obo:CL_0000540 ;
        wp:organism             obo:NCBITaxon_9606 ;
        wp:organismName         "Homo sapiens" ;
        wp:pathwayOntologyTag   obo:PW_0000003 , obo:PW_0000237 , obo:PW_0001251 ;
        foaf:img                <https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=png&pwTitle=Pathway:WP4919&oldid=140179> , <https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=svg&pwTitle=Pathway:WP4919&oldid=140179> ;
        foaf:page               <http://www.wikipathways.org/instance/WP4919_r140179> .

<https://identifiers.org/ensembl/ENSG00000138303>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "p50" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000138303> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000138303" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4919_r140179> , <http://rdf.wikipathways.org/Pathway/WP4919_r140179/Complex/a8ff1> , <http://rdf.wikipathways.org/Pathway/WP4919_r140179/Complex/d7b37> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000138303> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/51008> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/ASCC1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q8N9N2> , <https://identifiers.org/uniprot/H0YER2> , <https://identifiers.org/uniprot/H0YE76> , <https://identifiers.org/uniprot/E9PKM6> , <https://identifiers.org/uniprot/A0A5K1VW55> , <https://identifiers.org/uniprot/E9PJM2> , <https://identifiers.org/uniprot/H0YE79> , <https://identifiers.org/uniprot/A0A5F9ZH79> , <https://identifiers.org/uniprot/A0A024QZM0> , <https://identifiers.org/uniprot/A0A5F9ZGP6> , <https://identifiers.org/uniprot/E9PQ44> , <https://identifiers.org/uniprot/A0A5F9ZI37> , <https://identifiers.org/uniprot/E9PM82> , <https://identifiers.org/uniprot/A0A5F9ZHP1> , <https://identifiers.org/uniprot/E9PR40> , <https://identifiers.org/uniprot/E9PQZ6> , <https://identifiers.org/uniprot/H0YCB3> , <https://identifiers.org/uniprot/E9PL92> , <https://identifiers.org/uniprot/A0A5F9ZI10> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q18039908> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4919_r140179/DataNode/fae64> , <http://rdf.wikipathways.org/Pathway/WP4919_r140179/DataNode/bf769> , <http://rdf.wikipathways.org/Pathway/WP4919_r140179/DataNode/e9b3b> , <http://rdf.wikipathways.org/Pathway/WP4919_r140179/DataNode/b4c0f> , <http://rdf.wikipathways.org/Pathway/WP4919_r140179/DataNode/ecdaf> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/H0YER2> , <http://purl.uniprot.org/uniprot/A0A5F9ZI37> , <http://purl.uniprot.org/uniprot/A0A5F9ZH79> , <http://purl.uniprot.org/uniprot/H0YE79> , <http://purl.uniprot.org/uniprot/A0A024QZM0> , <http://purl.uniprot.org/uniprot/A0A5F9ZI10> , <http://purl.uniprot.org/uniprot/E9PL92> , <http://purl.uniprot.org/uniprot/Q8N9N2> , <http://purl.uniprot.org/uniprot/E9PQ44> , <http://purl.uniprot.org/uniprot/H0YCB3> , <http://purl.uniprot.org/uniprot/A0A5K1VW55> , <http://purl.uniprot.org/uniprot/E9PKM6> , <http://purl.uniprot.org/uniprot/E9PM82> , <http://purl.uniprot.org/uniprot/A0A5F9ZHP1> , <http://purl.uniprot.org/uniprot/E9PJM2> , <http://purl.uniprot.org/uniprot/E9PR40> , <http://purl.uniprot.org/uniprot/E9PQZ6> , <http://purl.uniprot.org/uniprot/H0YE76> , <http://purl.uniprot.org/uniprot/A0A5F9ZGP6> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000138303> .

<https://identifiers.org/chebi/CHEBI:57743>
        rdf:type            wp:Metabolite , wp:DataNode ;
        rdfs:label          "L-citrulline" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/RHGKLRLOHDJJDR-BYPYZUCNSA-N> ;
        dc:identifier       <https://identifiers.org/chebi/CHEBI:57743> ;
        dc:source           "ChEBI" ;
        dcterms:identifier  "CHEBI:57743" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4919_r140179> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:16349> , <https://identifiers.org/chebi/CHEBI:57743> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/9367> ;
        wp:bdbHmdb          <https://identifiers.org/hmdb/HMDB0000904> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/RHGKLRLOHDJJDR-BYPYZUCNSA-N> ;
        wp:bdbKeggCompound  <https://identifiers.org/kegg.compound/C00327> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID6992098> , <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID9750> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q408641> , <http://www.wikidata.org/entity/Q106345633> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4919_r140179/DataNode/f3b20> ;
        foaf:page           <https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:57743> .

<https://identifiers.org/homologene/496>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "TNF-α" ;
        dc:identifier       <https://identifiers.org/homologene/496> ;
        dc:source           "HomoloGene" ;
        dcterms:identifier  "496" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4919_r140179> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4919_r140179/DataNode/ea57c> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/homologene/496> .

<http://rdf.wikipathways.org/Pathway/WP4919_r140179/WP/Interaction/id97c0df21>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4919_r140179> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4919_r140179/Interaction/id97c0df21> ;
        wp:participants   <https://identifiers.org/ensembl/ENSG00000177606> , <https://identifiers.org/ensembl/ENSG00000107643> ;
        wp:source         <https://identifiers.org/ensembl/ENSG00000107643> ;
        wp:target         <https://identifiers.org/ensembl/ENSG00000177606> .

<http://rdf.wikipathways.org/Pathway/WP4919_r140179/WP/Interaction/id18d738b2>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4919_r140179> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4919_r140179/Interaction/id18d738b2> ;
        wp:participants   <https://identifiers.org/chebi/CHEBI:15377> , <http://rdf.wikipathways.org/Pathway/WP4919_r140179/WP/Interaction/id7743c6c2> ;
        wp:source         <https://identifiers.org/chebi/CHEBI:15377> ;
        wp:target         <http://rdf.wikipathways.org/Pathway/WP4919_r140179/WP/Interaction/id7743c6c2> .

<http://rdf.wikipathways.org/Pathway/WP4919_r140179/WP/Interaction/id92efa4bc>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4919_r140179> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4919_r140179/Interaction/id92efa4bc> ;
        wp:participants   <https://identifiers.org/hgnc/391> , <https://identifiers.org/interpro/IPR000403> ;
        wp:source         <https://identifiers.org/interpro/IPR000403> ;
        wp:target         <https://identifiers.org/hgnc/391> .

<https://identifiers.org/brenda/1.7.99.4>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "Nitrate reductase" ;
        dc:identifier       <https://identifiers.org/brenda/1.7.99.4> ;
        dc:source           "BRENDA" ;
        dcterms:identifier  "1.7.99.4" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4919_r140179> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4919_r140179/DataNode/b8d87> ;
        foaf:page           <https://www.brenda-enzymes.org/enzyme.php?ecno=1.7.99.4> .

<https://identifiers.org/chebi/CHEBI:48107>
        rdf:type            wp:Metabolite , wp:DataNode ;
        rdfs:label          "Nitrate" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/GRYLNZFGIOXLOG-UHFFFAOYSA-N> ;
        dc:identifier       <https://identifiers.org/chebi/CHEBI:48107> ;
        dc:source           "ChEBI" ;
        dcterms:identifier  "CHEBI:48107" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4919_r140179/WP/Interaction/id7743c6c2> , <https://identifiers.org/wikipathways/WP4919_r140179> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:48107> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/919> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/GRYLNZFGIOXLOG-UHFFFAOYSA-N> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID944> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q83320> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4919_r140179/DataNode/d22ee> ;
        foaf:page           <https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:48107> .

<https://identifiers.org/pmc/PMC9316482>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed Central" ;
        dcterms:identifier  "PMC9316482" ;
        cito:cites          <https://identifiers.org/wikipathways/WP4919> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/PMC9316482> .

<https://identifiers.org/ensembl/ENSG00000213341>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "IKKα" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000213341> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000213341" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4919_r140179> , <http://rdf.wikipathways.org/Pathway/WP4919_r140179/WP/Interaction/idc4dcb1f4> , <http://rdf.wikipathways.org/Pathway/WP4919_r140179/WP/Interaction/id7eed551e> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000213341> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/1147> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/CHUK> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/O15111> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q17861989> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4919_r140179/DataNode/cc14c> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/O15111> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000213341> .

<https://identifiers.org/ensembl/ENSG00000100906>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "IκBα" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSG00000100906> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSG00000100906" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4919_r140179> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000100906> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/4792> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/NFKBIA> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/G3V286> , <https://identifiers.org/uniprot/G3V3K1> , <https://identifiers.org/uniprot/A0A8V8TLE7> , <https://identifiers.org/uniprot/P25963> , <https://identifiers.org/uniprot/G3V2A2> , <https://identifiers.org/uniprot/G3V3I4> , <https://identifiers.org/uniprot/A0A8V8TLC3> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q15325101> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4919_r140179/DataNode/fc511> , <http://rdf.wikipathways.org/Pathway/WP4919_r140179/DataNode/b1b6d> , <http://rdf.wikipathways.org/Pathway/WP4919_r140179/DataNode/fb590> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/G3V3K1> , <http://purl.uniprot.org/uniprot/A0A8V8TLE7> , <http://purl.uniprot.org/uniprot/G3V2A2> , <http://purl.uniprot.org/uniprot/G3V3I4> , <http://purl.uniprot.org/uniprot/P25963> , <http://purl.uniprot.org/uniprot/G3V286> , <http://purl.uniprot.org/uniprot/A0A8V8TLC3> ;
        foaf:page           <https://www.ensembl.org/id/ENSG00000100906> .

<http://rdf.wikipathways.org/Pathway/WP4919_r140179/WP/Interaction/id31ec123d>
        rdf:type          wp:Conversion , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4919_r140179> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4919_r140179/Interaction/id31ec123d> ;
        wp:participants   <https://identifiers.org/hgnc/391> , <https://identifiers.org/ensembl/ENSG00000112062> ;
        wp:source         <https://identifiers.org/ensembl/ENSG00000112062> ;
        wp:target         <https://identifiers.org/hgnc/391> .
