@prefix biopax:  <http://www.biopax.org/release/biopax-level3.owl#> .
@prefix cito:    <http://purl.org/spar/cito/> .
@prefix dc:      <http://purl.org/dc/elements/1.1/> .
@prefix dcterms: <http://purl.org/dc/terms/> .
@prefix foaf:    <http://xmlns.com/foaf/0.1/> .
@prefix freq:    <http://purl.org/cld/freq/> .
@prefix gpml:    <http://vocabularies.wikipathways.org/gpml#> .
@prefix obo:     <http://purl.obolibrary.org/obo/> .
@prefix owl:     <http://www.w3.org/2002/07/owl#> .
@prefix pav:     <http://purl.org/pav/> .
@prefix prov:    <http://www.w3.org/ns/prov#> .
@prefix rdf:     <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix rdfs:    <http://www.w3.org/2000/01/rdf-schema#> .
@prefix skos:    <http://www.w3.org/2004/02/skos/core#> .
@prefix void:    <http://rdfs.org/ns/void#> .
@prefix wp:      <http://vocabularies.wikipathways.org/wp#> .
@prefix wprdf:   <http://rdf.wikipathways.org/> .
@prefix xsd:     <http://www.w3.org/2001/XMLSchema#> .

<http://rdf.wikipathways.org/Pathway/WP259_r140219/WP/Interaction/idfc9899a0>
        rdf:type          wp:Inhibition , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP259_r140219> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP259_r140219/Interaction/idfc9899a0> ;
        wp:participants   <https://identifiers.org/ncbigene/5111> , <https://identifiers.org/chebi/CHEBI:7565> ;
        wp:source         <https://identifiers.org/chebi/CHEBI:7565> ;
        wp:target         <https://identifiers.org/ncbigene/5111> .

<https://identifiers.org/pubmed/11139427>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "11139427" ;
        dcterms:isPartOf    <https://identifiers.org/ncbigene/2185> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/11139427> .

<https://identifiers.org/wikipathways/WP259_r140219>
        rdf:type               skos:Collection , wp:Pathway ;
        dc:identifier          <https://identifiers.org/wikipathways/WP259> ;
        dc:source              "WikiPathways" ;
        dc:title               "Nifedipine activity"@en ;
        dcterms:description    "Nifedipine (brand names Adalat, Nifediac, Cordipin, Nifedical, and Procardia) is a dihydropyridine calcium channel blocker. Its main uses are as an antianginal (especially in Prinzmetal's angina) and antihypertensive, although a large number of other indications have recently been found for this agent, such as Raynaud's phenomenon, premature labor, and painful spasms of the esophagus in cancer and tetanus patients. It is also commonly used for the small subset of pulmonary hypertension patients whose symptoms respond to calcium channel blockers.\n\nSource: [Wikipedia](https://en.wikipedia.org/wiki/Nifedipine)." ;
        dcterms:identifier     "WP259" ;
        cito:cites             <https://identifiers.org/pubmed/11139427> ;
        wp:diseaseOntologyTag  obo:DOID_10763 , obo:DOID_114 ;
        wp:isAbout             <http://rdf.wikipathways.org/Pathway/WP259_r140219> ;
        wp:ontologyTag         wp:Curation:AnalysisCollection , obo:PW_0001247 , obo:DOID_114 , obo:DOID_10763 ;
        wp:organism            obo:NCBITaxon_9606 ;
        wp:organismName        "Homo sapiens" ;
        wp:pathwayOntologyTag  obo:PW_0001247 ;
        foaf:img               <https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=svg&pwTitle=Pathway:WP259&oldid=140219> , <https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=png&pwTitle=Pathway:WP259&oldid=140219> ;
        foaf:page              <http://www.wikipathways.org/instance/WP259_r140219> .

<https://identifiers.org/ncbigene/2185>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "PTK2B" ;
        dc:identifier       <https://identifiers.org/ncbigene/2185> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "2185" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP259_r140219/WP/Interaction/idcc100c6b> , <https://identifiers.org/wikipathways/WP259_r140219> , <http://rdf.wikipathways.org/Pathway/WP259_r140219/WP/Interaction/id173af18f> ;
        dcterms:references  <https://identifiers.org/pubmed/11139427> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000120899> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/2185> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/PTK2B> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q14289> , <https://identifiers.org/uniprot/E5RJ77> , <https://identifiers.org/uniprot/E5RHL2> , <https://identifiers.org/uniprot/H0YB74> , <https://identifiers.org/uniprot/C9JHV9> , <https://identifiers.org/uniprot/E5RK84> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP259_r140219/DataNode/fa8> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/C9JHV9> , <http://purl.uniprot.org/uniprot/E5RK84> , <http://purl.uniprot.org/uniprot/H0YB74> , <http://purl.uniprot.org/uniprot/E5RHL2> , <http://purl.uniprot.org/uniprot/E5RJ77> , <http://purl.uniprot.org/uniprot/Q14289> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/2185> .

<https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=svg&pwTitle=Pathway:WP259&oldid=140219>
        rdf:type        foaf:Image ;
        dcterms:format  "image/svg+xml" .

<https://identifiers.org/chebi/CHEBI:7565>
        rdf:type            wp:DataNode , wp:Metabolite ;
        rdfs:label          "Nifedipine" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/HYIMSNHJOBLJNT-UHFFFAOYSA-N> ;
        dc:identifier       <https://identifiers.org/chebi/CHEBI:7565> ;
        dc:source           "ChEBI" ;
        dcterms:identifier  "CHEBI:7565" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP259_r140219/WP/Interaction/idb7dfd54c> , <https://identifiers.org/wikipathways/WP259_r140219> , <http://rdf.wikipathways.org/Pathway/WP259_r140219/WP/Interaction/idfc9899a0> , <http://rdf.wikipathways.org/Pathway/WP259_r140219/WP/Interaction/idcc100c6b> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:7565> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/4330> ;
        wp:bdbHmdb          <https://identifiers.org/hmdb/HMDB0015247> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/HYIMSNHJOBLJNT-UHFFFAOYSA-N> ;
        wp:bdbKeggCompound  <https://identifiers.org/kegg.compound/C07266> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID4485> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q39111> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP259_r140219/DataNode/ac4> ;
        foaf:page           <https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:7565> .

<https://identifiers.org/ncbigene/6647>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "SOD" ;
        dc:identifier       <https://identifiers.org/ncbigene/6647> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "6647" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP259_r140219> , <http://rdf.wikipathways.org/Pathway/WP259_r140219/WP/Interaction/iddd6d0ec6> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000142168> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/6647> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/SOD1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/V9HWC9> , <https://identifiers.org/uniprot/H7BYH4> , <https://identifiers.org/uniprot/P00441> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP259_r140219/DataNode/c20> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P00441> , <http://purl.uniprot.org/uniprot/V9HWC9> , <http://purl.uniprot.org/uniprot/H7BYH4> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/6647> .

<https://identifiers.org/hmdb/HMDB0003378>
        rdf:type            wp:DataNode , wp:Metabolite ;
        rdfs:label          "NO" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/MWUXSHHQAYIFBG-UHFFFAOYSA-N> ;
        dc:identifier       <https://identifiers.org/hmdb/HMDB0003378> ;
        dc:source           "HMDB" ;
        dcterms:identifier  "HMDB0003378" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP259_r140219/WP/Interaction/id91c1f3c3> , <https://identifiers.org/wikipathways/WP259_r140219> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:16480> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/127983> ;
        wp:bdbHmdb          <https://identifiers.org/hmdb/HMDB0003378> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/MWUXSHHQAYIFBG-UHFFFAOYSA-N> ;
        wp:bdbKeggCompound  <https://identifiers.org/kegg.compound/C00533> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID145068> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q207843> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP259_r140219/DataNode/c81ef> ;
        foaf:page           <http://www.hmdb.ca/metabolites/HMDB0003378> .

<http://rdf.wikipathways.org/Pathway/WP259_r140219/WP/Interaction/id7bc8eabf>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP259_r140219> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP259_r140219/Interaction/id7bc8eabf> ;
        wp:participants   <https://identifiers.org/ncbigene/3791> , <https://identifiers.org/uniprot/VEGF> ;
        wp:source         <https://identifiers.org/uniprot/VEGF> ;
        wp:target         <https://identifiers.org/ncbigene/3791> .

<https://doi.org/10.1016%2Fj.tiv.2016.03.009>
        rdf:type            wp:PublicationReference ;
        dc:source           "DOI" ;
        dcterms:identifier  "10.1016/j.tiv.2016.03.009" ;
        cito:cites          <https://identifiers.org/wikipathways/WP259> .

<http://rdf.wikipathways.org/Pathway/WP259_r140219/WP/Interaction/id4152553>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP259_r140219> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP259_r140219/Interaction/id4152553> ;
        wp:participants   <https://identifiers.org/ncbigene/5594> , <https://identifiers.org/ncbigene/5604> ;
        wp:source         <https://identifiers.org/ncbigene/5604> ;
        wp:target         <https://identifiers.org/ncbigene/5594> .

<https://identifiers.org/ncbigene/50818>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "PKC" ;
        dc:identifier       <https://identifiers.org/ncbigene/50818> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "50818" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP259_r140219/WP/Interaction/idfeb17645> , <http://rdf.wikipathways.org/Pathway/WP259_r140219/WP/Interaction/idfd513471> , <https://identifiers.org/wikipathways/WP259_r140219> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/50818> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP259_r140219/DataNode/da6> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/50818> .

<https://identifiers.org/ncbigene/5604>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "MAP2K1" ;
        dc:identifier       <https://identifiers.org/ncbigene/5604> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "5604" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP259_r140219/WP/Interaction/id4152553> , <https://identifiers.org/wikipathways/WP259_r140219> , <http://rdf.wikipathways.org/Pathway/WP259_r140219/WP/Interaction/id173af18f> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000169032> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/5604> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/MAP2K1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A8I5KYS7> , <https://identifiers.org/uniprot/A0A8I5QJ96> , <https://identifiers.org/uniprot/A0A8I5QJP8> , <https://identifiers.org/uniprot/A0A8I5KYB4> , <https://identifiers.org/uniprot/H3BRW9> , <https://identifiers.org/uniprot/A0A8I5KVF6> , <https://identifiers.org/uniprot/A0A8I5KXN4> , <https://identifiers.org/uniprot/B4DFY5> , <https://identifiers.org/uniprot/A4QPA9> , <https://identifiers.org/uniprot/A0A8I5KRX5> , <https://identifiers.org/uniprot/A0A8I5QJL9> , <https://identifiers.org/uniprot/Q02750> , <https://identifiers.org/uniprot/A0A8I5QJC1> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP259_r140219/DataNode/b58> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A8I5QJL9> , <http://purl.uniprot.org/uniprot/H3BRW9> , <http://purl.uniprot.org/uniprot/A0A8I5QJC1> , <http://purl.uniprot.org/uniprot/A0A8I5KYS7> , <http://purl.uniprot.org/uniprot/A0A8I5KYB4> , <http://purl.uniprot.org/uniprot/A0A8I5KVF6> , <http://purl.uniprot.org/uniprot/B4DFY5> , <http://purl.uniprot.org/uniprot/A0A8I5KXN4> , <http://purl.uniprot.org/uniprot/A0A8I5KRX5> , <http://purl.uniprot.org/uniprot/A4QPA9> , <http://purl.uniprot.org/uniprot/A0A8I5QJ96> , <http://purl.uniprot.org/uniprot/A0A8I5QJP8> , <http://purl.uniprot.org/uniprot/Q02750> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/5604> .

<http://rdf.wikipathways.org/Pathway/WP259_r140219/WP/Interaction/idcc100c6b>
        rdf:type          wp:Inhibition , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP259_r140219> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP259_r140219/Interaction/idcc100c6b> ;
        wp:participants   <https://identifiers.org/ncbigene/2185> , <https://identifiers.org/chebi/CHEBI:7565> ;
        wp:source         <https://identifiers.org/chebi/CHEBI:7565> ;
        wp:target         <https://identifiers.org/ncbigene/2185> .

<https://identifiers.org/ncbigene/3791>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "KDR/FLK1" ;
        dc:identifier       <https://identifiers.org/ncbigene/3791> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "3791" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP259_r140219> , <http://rdf.wikipathways.org/Pathway/WP259_r140219/WP/Interaction/id7bc8eabf> , <http://rdf.wikipathways.org/Pathway/WP259_r140219/WP/Interaction/id91c1f3c3> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000128052> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/3791> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/KDR> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/P35968> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP259_r140219/DataNode/dec86> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P35968> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/3791> .

<https://identifiers.org/ncbigene/5111>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "PCNA" ;
        dc:identifier       <https://identifiers.org/ncbigene/5111> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "5111" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP259_r140219/WP/Interaction/idfc9899a0> , <https://identifiers.org/wikipathways/WP259_r140219> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000132646> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/5111> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/PCNA> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/P12004> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP259_r140219/DataNode/a06> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P12004> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/5111> .

<http://rdf.wikipathways.org/Pathway/WP259_r140219/WP/Interaction/iddd6d0ec6>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP259_r140219> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP259_r140219/Interaction/iddd6d0ec6> ;
        wp:participants   <https://identifiers.org/ncbigene/6647> , <https://identifiers.org/uniprot/VEGF> ;
        wp:source         <https://identifiers.org/uniprot/VEGF> ;
        wp:target         <https://identifiers.org/ncbigene/6647> .

<http://rdf.wikipathways.org/Pathway/WP259_r140219/WP/Interaction/id91c1f3c3>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP259_r140219> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP259_r140219/Interaction/id91c1f3c3> ;
        wp:participants   <https://identifiers.org/hmdb/HMDB0003378> , <https://identifiers.org/ncbigene/3791> ;
        wp:source         <https://identifiers.org/ncbigene/3791> ;
        wp:target         <https://identifiers.org/hmdb/HMDB0003378> .

<https://identifiers.org/chebi/CHEBI:16113>
        rdf:type            wp:Metabolite , wp:DataNode ;
        rdfs:label          "Cholesterol" ;
        rdfs:seeAlso        <https://identifiers.org/inchikey/HVYWMOMLDIMFJA-DPAQBDIFSA-N> ;
        dc:identifier       <https://identifiers.org/chebi/CHEBI:16113> ;
        dc:source           "ChEBI" ;
        dcterms:identifier  "CHEBI:16113" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP259_r140219> ;
        wp:bdbChEBI         <https://identifiers.org/chebi/CHEBI:16113> ;
        wp:bdbChemspider    <https://identifiers.org/chemspider/5775> ;
        wp:bdbHmdb          <https://identifiers.org/hmdb/HMDB0000067> ;
        wp:bdbInChIKey      <https://identifiers.org/inchikey/HVYWMOMLDIMFJA-DPAQBDIFSA-N> ;
        wp:bdbKeggCompound  <https://identifiers.org/kegg.compound/C00187> ;
        wp:bdbLipidMaps     <https://identifiers.org/lipidmaps/LMST01010001> ;
        wp:bdbPubChem       <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID5997> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q43656> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP259_r140219/DataNode/fd5> ;
        owl:sameAs          <https://www.lipidmaps.org/rdf/LMST01010001> , <https://swisslipids.org/rdf/SLM_000000287> ;
        foaf:page           <https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:16113> .

<https://identifiers.org/ncbigene/624>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "BDKRB2" ;
        dc:identifier       <https://identifiers.org/ncbigene/624> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "624" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP259_r140219/WP/Interaction/idb7dfd54c> , <http://rdf.wikipathways.org/Pathway/WP259_r140219/WP/Interaction/idfd513471> , <https://identifiers.org/wikipathways/WP259_r140219> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000168398> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/624> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/BDKRB2> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/P30411> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP259_r140219/DataNode/c4566> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P30411> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/624> .

<https://identifiers.org/ncbigene/5594>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "MAPK1" ;
        dc:identifier       <https://identifiers.org/ncbigene/5594> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "5594" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP259_r140219> , <http://rdf.wikipathways.org/Pathway/WP259_r140219/WP/Interaction/id4152553> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000100030> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/5594> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/MAPK1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q1HBJ4> , <https://identifiers.org/uniprot/P28482> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP259_r140219/DataNode/e1c> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P28482> , <http://purl.uniprot.org/uniprot/Q1HBJ4> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/5594> .

<http://rdf.wikipathways.org/Pathway/WP259_r140219/WP/Interaction/idfd513471>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP259_r140219> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP259_r140219/Interaction/idfd513471> ;
        wp:participants   <https://identifiers.org/ncbigene/50818> , <https://identifiers.org/ncbigene/624> ;
        wp:source         <https://identifiers.org/ncbigene/624> ;
        wp:target         <https://identifiers.org/ncbigene/50818> .

<https://identifiers.org/ncbigene/1576>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "CYP3A4" ;
        dc:identifier       <https://identifiers.org/ncbigene/1576> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "1576" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP259_r140219> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000160868> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/1576> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/CYP3A4> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/E7EVM8> , <https://identifiers.org/uniprot/Q6GRK0> , <https://identifiers.org/uniprot/A0A494C0W7> , <https://identifiers.org/uniprot/P08684> , <https://identifiers.org/uniprot/C9JBD2> , <https://identifiers.org/uniprot/A0A499FJM4> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP259_r140219/DataNode/ccb> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A494C0W7> , <http://purl.uniprot.org/uniprot/P08684> , <http://purl.uniprot.org/uniprot/C9JBD2> , <http://purl.uniprot.org/uniprot/E7EVM8> , <http://purl.uniprot.org/uniprot/A0A499FJM4> , <http://purl.uniprot.org/uniprot/Q6GRK0> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/1576> .

<http://rdf.wikipathways.org/Pathway/WP259_r140219/WP/Interaction/idfeb17645>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP259_r140219> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP259_r140219/Interaction/idfeb17645> ;
        wp:participants   <https://identifiers.org/uniprot/VEGF> , <https://identifiers.org/ncbigene/50818> ;
        wp:source         <https://identifiers.org/ncbigene/50818> ;
        wp:target         <https://identifiers.org/uniprot/VEGF> .

obo:NCBITaxon_9606  obo:NCIT_C179773  "9606" .

<https://identifiers.org/uniprot/VEGF>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "VEGF" ;
        dc:identifier       <https://identifiers.org/uniprot/VEGF> ;
        dc:source           "UniProtKB" ;
        dcterms:identifier  "VEGF" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP259_r140219/WP/Interaction/id7bc8eabf> , <https://identifiers.org/wikipathways/WP259_r140219> , <http://rdf.wikipathways.org/Pathway/WP259_r140219/WP/Interaction/iddd6d0ec6> , <http://rdf.wikipathways.org/Pathway/WP259_r140219/WP/Interaction/idfeb17645> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/VEGF> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP259_r140219/DataNode/ba7> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/VEGF> ;
        foaf:page           <http://www.uniprot.org/uniprot/VEGF> .

<http://rdf.wikipathways.org/Pathway/WP259_r140219/WP/Interaction/idb7dfd54c>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP259_r140219> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP259_r140219/Interaction/idb7dfd54c> ;
        wp:participants   <https://identifiers.org/ncbigene/624> , <https://identifiers.org/chebi/CHEBI:7565> ;
        wp:source         <https://identifiers.org/chebi/CHEBI:7565> ;
        wp:target         <https://identifiers.org/ncbigene/624> .

<http://rdf.wikipathways.org/Pathway/WP259_r140219/WP/Interaction/id173af18f>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP259_r140219> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP259_r140219/Interaction/id173af18f> ;
        wp:participants   <https://identifiers.org/ncbigene/5604> , <https://identifiers.org/ncbigene/2185> ;
        wp:source         <https://identifiers.org/ncbigene/2185> ;
        wp:target         <https://identifiers.org/ncbigene/5604> .

<https://identifiers.org/wikipathways/WP259>
        pav:hasVersion  <https://identifiers.org/wikipathways/WP259_r140219> .

<https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=png&pwTitle=Pathway:WP259&oldid=140219>
        rdf:type        foaf:Image ;
        dcterms:format  "image/png" .
