@prefix biopax:  <http://www.biopax.org/release/biopax-level3.owl#> .
@prefix cito:    <http://purl.org/spar/cito/> .
@prefix dc:      <http://purl.org/dc/elements/1.1/> .
@prefix dcterms: <http://purl.org/dc/terms/> .
@prefix foaf:    <http://xmlns.com/foaf/0.1/> .
@prefix freq:    <http://purl.org/cld/freq/> .
@prefix gpml:    <http://vocabularies.wikipathways.org/gpml#> .
@prefix obo:     <http://purl.obolibrary.org/obo/> .
@prefix owl:     <http://www.w3.org/2002/07/owl#> .
@prefix pav:     <http://purl.org/pav/> .
@prefix prov:    <http://www.w3.org/ns/prov#> .
@prefix rdf:     <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix rdfs:    <http://www.w3.org/2000/01/rdf-schema#> .
@prefix skos:    <http://www.w3.org/2004/02/skos/core#> .
@prefix void:    <http://rdfs.org/ns/void#> .
@prefix wp:      <http://vocabularies.wikipathways.org/wp#> .
@prefix wprdf:   <http://rdf.wikipathways.org/> .
@prefix xsd:     <http://www.w3.org/2001/XMLSchema#> .

<https://identifiers.org/ncbigene/1499>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "CTNNB1" ;
        dc:identifier       <https://identifiers.org/ncbigene/1499> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "1499" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP363_r138524/WP/Interaction/a89cf> , <http://rdf.wikipathways.org/Pathway/WP363_r138524/WP/Interaction/f77df> , <https://identifiers.org/wikipathways/WP363_r138524> , <http://rdf.wikipathways.org/Pathway/WP363_r138524/WP/Interaction/d8911> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000168036> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/1499> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/CTNNB1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A2R8Y804> , <https://identifiers.org/uniprot/A0A024R2Q3> , <https://identifiers.org/uniprot/P35222> , <https://identifiers.org/uniprot/A0A2R8Y7Z0> , <https://identifiers.org/uniprot/A0A2R8Y5C3> , <https://identifiers.org/uniprot/C9IZ65> , <https://identifiers.org/uniprot/A0A2R8Y543> , <https://identifiers.org/uniprot/A0A2R8Y5A3> , <https://identifiers.org/uniprot/A0A2R8YG06> , <https://identifiers.org/uniprot/A0A2R8Y750> , <https://identifiers.org/uniprot/A0A2R8Y6G0> , <https://identifiers.org/uniprot/A0A2R8YCH5> , <https://identifiers.org/uniprot/B4DGU4> , <https://identifiers.org/uniprot/A0A2R8Y815> , <https://identifiers.org/uniprot/A0A2R8Y5Z1> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP363_r138524/DataNode/c8926> , <http://rdf.wikipathways.org/Pathway/WP363_r138524/DataNode/e8ec2> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A2R8Y543> , <http://purl.uniprot.org/uniprot/A0A2R8Y5A3> , <http://purl.uniprot.org/uniprot/A0A2R8Y5Z1> , <http://purl.uniprot.org/uniprot/A0A2R8YCH5> , <http://purl.uniprot.org/uniprot/A0A2R8Y6G0> , <http://purl.uniprot.org/uniprot/A0A2R8Y7Z0> , <http://purl.uniprot.org/uniprot/A0A024R2Q3> , <http://purl.uniprot.org/uniprot/A0A2R8Y815> , <http://purl.uniprot.org/uniprot/B4DGU4> , <http://purl.uniprot.org/uniprot/C9IZ65> , <http://purl.uniprot.org/uniprot/A0A2R8Y750> , <http://purl.uniprot.org/uniprot/A0A2R8Y804> , <http://purl.uniprot.org/uniprot/A0A2R8YG06> , <http://purl.uniprot.org/uniprot/P35222> , <http://purl.uniprot.org/uniprot/A0A2R8Y5C3> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/1499> .

<https://identifiers.org/ncbigene/1857>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "DVL3" ;
        dc:identifier       <https://identifiers.org/ncbigene/1857> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "1857" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP363_r138524/WP/Interaction/bef9d> , <https://identifiers.org/wikipathways/WP363_r138524> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000161202> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/1857> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/DVL3> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/F8WCF1> , <https://identifiers.org/uniprot/Q92997> , <https://identifiers.org/uniprot/A0A3B3ITC6> , <https://identifiers.org/uniprot/A0A3B3ISG4> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP363_r138524/DataNode/a0c3d> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/F8WCF1> , <http://purl.uniprot.org/uniprot/A0A3B3ITC6> , <http://purl.uniprot.org/uniprot/A0A3B3ISG4> , <http://purl.uniprot.org/uniprot/Q92997> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/1857> .

<https://identifiers.org/ncbigene/53944>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "CSNK1G1" ;
        dc:identifier       <https://identifiers.org/ncbigene/53944> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "53944" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP363_r138524> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000169118> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/53944> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/CSNK1G1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A0U1RR31> , <https://identifiers.org/uniprot/A0A024R5W3> , <https://identifiers.org/uniprot/A0A0U1RRH5> , <https://identifiers.org/uniprot/A0A0U1RR14> , <https://identifiers.org/uniprot/U3KQA5> , <https://identifiers.org/uniprot/A0A024R604> , <https://identifiers.org/uniprot/Q8IXA3> , <https://identifiers.org/uniprot/A0A0U1RQN5> , <https://identifiers.org/uniprot/A0A0U1RQU4> , <https://identifiers.org/uniprot/U3KQB3> , <https://identifiers.org/uniprot/A0A0U1RQY7> , <https://identifiers.org/uniprot/A0A0U1RQH9> , <https://identifiers.org/uniprot/Q9HCP0> , <https://identifiers.org/uniprot/A0A0U1RQT7> , <https://identifiers.org/uniprot/A0A0U1RQK6> , <https://identifiers.org/uniprot/A0A0U1RQG9> , <https://identifiers.org/uniprot/A0A0U1RQK2> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP363_r138524/DataNode/c0665> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A0U1RRH5> , <http://purl.uniprot.org/uniprot/Q8IXA3> , <http://purl.uniprot.org/uniprot/A0A0U1RQU4> , <http://purl.uniprot.org/uniprot/A0A0U1RQK6> , <http://purl.uniprot.org/uniprot/A0A0U1RQT7> , <http://purl.uniprot.org/uniprot/A0A0U1RQK2> , <http://purl.uniprot.org/uniprot/A0A024R604> , <http://purl.uniprot.org/uniprot/A0A0U1RQG9> , <http://purl.uniprot.org/uniprot/A0A0U1RQH9> , <http://purl.uniprot.org/uniprot/A0A0U1RR31> , <http://purl.uniprot.org/uniprot/A0A024R5W3> , <http://purl.uniprot.org/uniprot/Q9HCP0> , <http://purl.uniprot.org/uniprot/A0A0U1RR14> , <http://purl.uniprot.org/uniprot/U3KQA5> , <http://purl.uniprot.org/uniprot/U3KQB3> , <http://purl.uniprot.org/uniprot/A0A0U1RQN5> , <http://purl.uniprot.org/uniprot/A0A0U1RQY7> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/53944> .

<https://identifiers.org/ncbigene/1452>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "CSNK1A1" ;
        dc:identifier       <https://identifiers.org/ncbigene/1452> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "1452" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP363_r138524> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000113712> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/1452> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/CSNK1A1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/D6RGE5> , <https://identifiers.org/uniprot/A0A590UJ43> , <https://identifiers.org/uniprot/P48729> , <https://identifiers.org/uniprot/E7ETM0> , <https://identifiers.org/uniprot/D6REM4> , <https://identifiers.org/uniprot/A0A590UK94> , <https://identifiers.org/uniprot/U3KQK7> , <https://identifiers.org/uniprot/E5RG27> , <https://identifiers.org/uniprot/U3KQ83> , <https://identifiers.org/uniprot/H0Y9X2> , <https://identifiers.org/uniprot/A0A5F9W493> , <https://identifiers.org/uniprot/U3KPX3> , <https://identifiers.org/uniprot/A0A590UJQ7> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP363_r138524/DataNode/b0502> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/U3KQ83> , <http://purl.uniprot.org/uniprot/U3KPX3> , <http://purl.uniprot.org/uniprot/P48729> , <http://purl.uniprot.org/uniprot/A0A590UJ43> , <http://purl.uniprot.org/uniprot/H0Y9X2> , <http://purl.uniprot.org/uniprot/D6REM4> , <http://purl.uniprot.org/uniprot/A0A590UK94> , <http://purl.uniprot.org/uniprot/A0A5F9W493> , <http://purl.uniprot.org/uniprot/D6RGE5> , <http://purl.uniprot.org/uniprot/E7ETM0> , <http://purl.uniprot.org/uniprot/U3KQK7> , <http://purl.uniprot.org/uniprot/E5RG27> , <http://purl.uniprot.org/uniprot/A0A590UJQ7> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/1452> .

<https://identifiers.org/ncbigene/207>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "AKT1" ;
        dc:identifier       <https://identifiers.org/ncbigene/207> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "207" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP363_r138524/WP/Interaction/id822d66cd> , <http://rdf.wikipathways.org/Pathway/WP363_r138524/WP/Interaction/id5e4055e1> , <https://identifiers.org/wikipathways/WP363_r138524> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000142208> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/207> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/AKT1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/P31749> , <https://identifiers.org/uniprot/A0A804HJM6> , <https://identifiers.org/uniprot/B0LPE5> , <https://identifiers.org/uniprot/G3V2I6> , <https://identifiers.org/uniprot/A0A087WY56> , <https://identifiers.org/uniprot/G3V3X1> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP363_r138524/DataNode/a1087> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/G3V2I6> , <http://purl.uniprot.org/uniprot/B0LPE5> , <http://purl.uniprot.org/uniprot/A0A804HJM6> , <http://purl.uniprot.org/uniprot/A0A087WY56> , <http://purl.uniprot.org/uniprot/P31749> , <http://purl.uniprot.org/uniprot/G3V3X1> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/207> .

<https://identifiers.org/ncbigene/5468>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "PPARG" ;
        dc:identifier       <https://identifiers.org/ncbigene/5468> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "5468" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP363_r138524> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000132170> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/5468> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/PPARG> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A494C012> , <https://identifiers.org/uniprot/A0A494C0D9> , <https://identifiers.org/uniprot/E9PFV3> , <https://identifiers.org/uniprot/A0A804HJN2> , <https://identifiers.org/uniprot/A0A804HLH1> , <https://identifiers.org/uniprot/A0A804HL89> , <https://identifiers.org/uniprot/A0A804HIG1> , <https://identifiers.org/uniprot/Q6L9M1> , <https://identifiers.org/uniprot/P37231> , <https://identifiers.org/uniprot/E9PFX5> , <https://identifiers.org/uniprot/A0A494C0T3> , <https://identifiers.org/uniprot/A0A3P3ZKM0> , <https://identifiers.org/uniprot/E7EUD1> , <https://identifiers.org/uniprot/E9PFV2> , <https://identifiers.org/uniprot/E7EU07> , <https://identifiers.org/uniprot/A0A499FIV4> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP363_r138524/DataNode/e7ab7> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/E7EUD1> , <http://purl.uniprot.org/uniprot/A0A3P3ZKM0> , <http://purl.uniprot.org/uniprot/Q6L9M1> , <http://purl.uniprot.org/uniprot/A0A494C0D9> , <http://purl.uniprot.org/uniprot/A0A804HIG1> , <http://purl.uniprot.org/uniprot/E9PFV3> , <http://purl.uniprot.org/uniprot/E7EU07> , <http://purl.uniprot.org/uniprot/A0A494C012> , <http://purl.uniprot.org/uniprot/E9PFX5> , <http://purl.uniprot.org/uniprot/A0A804HJN2> , <http://purl.uniprot.org/uniprot/P37231> , <http://purl.uniprot.org/uniprot/A0A804HLH1> , <http://purl.uniprot.org/uniprot/A0A804HL89> , <http://purl.uniprot.org/uniprot/A0A494C0T3> , <http://purl.uniprot.org/uniprot/E9PFV2> , <http://purl.uniprot.org/uniprot/A0A499FIV4> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/5468> .

<https://identifiers.org/ncbigene/4919>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "ROR1" ;
        dc:identifier       <https://identifiers.org/ncbigene/4919> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "4919" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP363_r138524> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000185483> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/4919> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/ROR1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q01973> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP363_r138524/DataNode/fd6b8> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q01973> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/4919> .

<https://identifiers.org/ncbigene/8312>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "AXIN1" ;
        dc:identifier       <https://identifiers.org/ncbigene/8312> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "8312" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP363_r138524/WP/Interaction/id8f3d1280> , <https://identifiers.org/wikipathways/WP363_r138524> , <http://rdf.wikipathways.org/Pathway/WP363_r138524/WP/Interaction/idde943844> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000103126> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/8312> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/AXIN1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A0S2Z4R0> , <https://identifiers.org/uniprot/A0A0S2Z4S3> , <https://identifiers.org/uniprot/H0Y830> , <https://identifiers.org/uniprot/O15169> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP363_r138524/DataNode/ab859> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/H0Y830> , <http://purl.uniprot.org/uniprot/A0A0S2Z4R0> , <http://purl.uniprot.org/uniprot/O15169> , <http://purl.uniprot.org/uniprot/A0A0S2Z4S3> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/8312> .

<http://rdf.wikipathways.org/Pathway/WP363_r138524/WP/Interaction/d5f45>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP363_r138524> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP363_r138524/Interaction/d5f45> ;
        wp:participants   <https://identifiers.org/ncbigene/6885> ;
        wp:source         <https://identifiers.org/ncbigene/6885> ;
        wp:target         <https://identifiers.org/ncbigene/6885> .

<http://rdf.wikipathways.org/Pathway/WP363_r138524/WP/Interaction/f77df>
        rdf:type          wp:Inhibition , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP363_r138524> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP363_r138524/Interaction/f77df> ;
        wp:participants   <https://identifiers.org/ncbigene/1499> , <https://identifiers.org/ncbigene/51701> ;
        wp:source         <https://identifiers.org/ncbigene/51701> ;
        wp:target         <https://identifiers.org/ncbigene/1499> .

<https://identifiers.org/ncbigene/6925>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "TCF4" ;
        dc:identifier       <https://identifiers.org/ncbigene/6925> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "6925" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP363_r138524> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000196628> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/6925> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/TCF4> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/H3BRF7> , <https://identifiers.org/uniprot/A0A1B0GV10> , <https://identifiers.org/uniprot/H3BUQ3> , <https://identifiers.org/uniprot/H3BNZ2> , <https://identifiers.org/uniprot/H3BML7> , <https://identifiers.org/uniprot/A0A1B0GXH5> , <https://identifiers.org/uniprot/A0A024R2C0> , <https://identifiers.org/uniprot/H3BTP3> , <https://identifiers.org/uniprot/H3BME8> , <https://identifiers.org/uniprot/H3BTZ0> , <https://identifiers.org/uniprot/A0A0D9SFX5> , <https://identifiers.org/uniprot/A0A1B0GTP2> , <https://identifiers.org/uniprot/H3BT95> , <https://identifiers.org/uniprot/A0A0D9SG44> , <https://identifiers.org/uniprot/E9PH57> , <https://identifiers.org/uniprot/A0A0D9SEX8> , <https://identifiers.org/uniprot/G0LNT7> , <https://identifiers.org/uniprot/A0A6Q8PGE3> , <https://identifiers.org/uniprot/A0A1B0GUT3> , <https://identifiers.org/uniprot/A0A1B0GVB8> , <https://identifiers.org/uniprot/A0A0D9SEK1> , <https://identifiers.org/uniprot/H3BTM9> , <https://identifiers.org/uniprot/A0A0D9SF97> , <https://identifiers.org/uniprot/A0A0D9SF18> , <https://identifiers.org/uniprot/H3BT24> , <https://identifiers.org/uniprot/A0A0D9SGE5> , <https://identifiers.org/uniprot/H3BPG3> , <https://identifiers.org/uniprot/G0LNT4> , <https://identifiers.org/uniprot/A0A075B723> , <https://identifiers.org/uniprot/H3BMC8> , <https://identifiers.org/uniprot/H3BPJ7> , <https://identifiers.org/uniprot/A0A1B0GVR6> , <https://identifiers.org/uniprot/A0A0D9SG61> , <https://identifiers.org/uniprot/A0A1B0GW91> , <https://identifiers.org/uniprot/K7ESI6> , <https://identifiers.org/uniprot/P15884> , <https://identifiers.org/uniprot/A0A0D9SGJ4> , <https://identifiers.org/uniprot/A0A0D9SG55> , <https://identifiers.org/uniprot/A0A0D9SGE7> , <https://identifiers.org/uniprot/H3BTC3> , <https://identifiers.org/uniprot/A0A0D9SG78> , <https://identifiers.org/uniprot/A0A0E3D6N2> , <https://identifiers.org/uniprot/A0A0D9SFZ1> , <https://identifiers.org/uniprot/H3BP59> , <https://identifiers.org/uniprot/A0A0D9SGE4> , <https://identifiers.org/uniprot/A0A1B0GWD5> , <https://identifiers.org/uniprot/A0A0D9SFU5> , <https://identifiers.org/uniprot/A0A0D9SEZ3> , <https://identifiers.org/uniprot/H3BNI2> , <https://identifiers.org/uniprot/A0A0D9SGH7> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP363_r138524/DataNode/fe375> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A0D9SGH7> , <http://purl.uniprot.org/uniprot/H3BP59> , <http://purl.uniprot.org/uniprot/A0A0D9SG55> , <http://purl.uniprot.org/uniprot/H3BTC3> , <http://purl.uniprot.org/uniprot/A0A024R2C0> , <http://purl.uniprot.org/uniprot/A0A1B0GV10> , <http://purl.uniprot.org/uniprot/A0A0D9SFU5> , <http://purl.uniprot.org/uniprot/H3BTZ0> , <http://purl.uniprot.org/uniprot/A0A0D9SG61> , <http://purl.uniprot.org/uniprot/A0A0D9SG78> , <http://purl.uniprot.org/uniprot/G0LNT7> , <http://purl.uniprot.org/uniprot/A0A0D9SGJ4> , <http://purl.uniprot.org/uniprot/A0A0D9SFX5> , <http://purl.uniprot.org/uniprot/A0A0E3D6N2> , <http://purl.uniprot.org/uniprot/A0A1B0GXH5> , <http://purl.uniprot.org/uniprot/A0A0D9SG44> , <http://purl.uniprot.org/uniprot/A0A0D9SEZ3> , <http://purl.uniprot.org/uniprot/P15884> , <http://purl.uniprot.org/uniprot/A0A0D9SEK1> , <http://purl.uniprot.org/uniprot/A0A1B0GWD5> , <http://purl.uniprot.org/uniprot/H3BRF7> , <http://purl.uniprot.org/uniprot/A0A1B0GVR6> , <http://purl.uniprot.org/uniprot/H3BML7> , <http://purl.uniprot.org/uniprot/G0LNT4> , <http://purl.uniprot.org/uniprot/H3BTM9> , <http://purl.uniprot.org/uniprot/K7ESI6> , <http://purl.uniprot.org/uniprot/A0A1B0GVB8> , <http://purl.uniprot.org/uniprot/H3BNI2> , <http://purl.uniprot.org/uniprot/H3BME8> , <http://purl.uniprot.org/uniprot/H3BUQ3> , <http://purl.uniprot.org/uniprot/H3BTP3> , <http://purl.uniprot.org/uniprot/H3BT24> , <http://purl.uniprot.org/uniprot/A0A0D9SEX8> , <http://purl.uniprot.org/uniprot/E9PH57> , <http://purl.uniprot.org/uniprot/A0A1B0GW91> , <http://purl.uniprot.org/uniprot/A0A0D9SGE5> , <http://purl.uniprot.org/uniprot/A0A075B723> , <http://purl.uniprot.org/uniprot/A0A6Q8PGE3> , <http://purl.uniprot.org/uniprot/A0A1B0GUT3> , <http://purl.uniprot.org/uniprot/A0A0D9SF18> , <http://purl.uniprot.org/uniprot/A0A1B0GTP2> , <http://purl.uniprot.org/uniprot/H3BPG3> , <http://purl.uniprot.org/uniprot/H3BPJ7> , <http://purl.uniprot.org/uniprot/A0A0D9SF97> , <http://purl.uniprot.org/uniprot/H3BMC8> , <http://purl.uniprot.org/uniprot/A0A0D9SGE7> , <http://purl.uniprot.org/uniprot/H3BT95> , <http://purl.uniprot.org/uniprot/A0A0D9SGE4> , <http://purl.uniprot.org/uniprot/H3BNZ2> , <http://purl.uniprot.org/uniprot/A0A0D9SFZ1> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/6925> .

<http://rdf.wikipathways.org/Pathway/WP363_r138524/WP/Interaction/b21d1>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP363_r138524> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP363_r138524/Interaction/b21d1> ;
        wp:participants   <https://identifiers.org/ncbigene/1856> , <https://identifiers.org/ncbigene/5578> ;
        wp:source         <https://identifiers.org/ncbigene/5578> ;
        wp:target         <https://identifiers.org/ncbigene/1856> .

<https://identifiers.org/ncbigene/2697>
        rdf:type            wp:Rna , wp:DataNode ;
        rdfs:label          "GJA1" ;
        dc:identifier       <https://identifiers.org/ncbigene/2697> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "2697" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP363_r138524> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000152661> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/2697> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/GJA1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/P17302> , <https://identifiers.org/uniprot/A0A654IBU3> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP363_r138524/DataNode/aa2f6> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P17302> , <http://purl.uniprot.org/uniprot/A0A654IBU3> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/2697> .

<http://rdf.wikipathways.org/Pathway/WP363_r138524/WP/Interaction/idb7fc1a36>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP363_r138524> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP363_r138524/Interaction/idb7fc1a36> ;
        wp:participants   <https://identifiers.org/ncbigene/1855> , <https://identifiers.org/ncbigene/4040> ;
        wp:source         <https://identifiers.org/ncbigene/4040> ;
        wp:target         <https://identifiers.org/ncbigene/1855> .

<https://identifiers.org/pubmed/20067622>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "20067622" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP363_r138524> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/20067622> .

<https://identifiers.org/ncbigene/1856>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "DVL2" ;
        dc:identifier       <https://identifiers.org/ncbigene/1856> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "1856" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP363_r138524> , <http://rdf.wikipathways.org/Pathway/WP363_r138524/WP/Interaction/id8f3d1280> , <http://rdf.wikipathways.org/Pathway/WP363_r138524/WP/Interaction/b3fef> , <http://rdf.wikipathways.org/Pathway/WP363_r138524/WP/Interaction/b21d1> , <http://rdf.wikipathways.org/Pathway/WP363_r138524/WP/Interaction/idaf80b52d> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000004975> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/1856> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/DVL2> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/O14641> , <https://identifiers.org/uniprot/I3L2W9> , <https://identifiers.org/uniprot/I3L2N2> , <https://identifiers.org/uniprot/I3L0M7> , <https://identifiers.org/uniprot/I3L0Z8> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP363_r138524/DataNode/edd99> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/I3L2W9> , <http://purl.uniprot.org/uniprot/I3L2N2> , <http://purl.uniprot.org/uniprot/I3L0Z8> , <http://purl.uniprot.org/uniprot/O14641> , <http://purl.uniprot.org/uniprot/I3L0M7> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/1856> .

<https://identifiers.org/ncbigene/5582>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "PRKCG" ;
        dc:identifier       <https://identifiers.org/ncbigene/5582> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "5582" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP363_r138524> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000126583> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/5582> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/PRKCG> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/M0R0I9> , <https://identifiers.org/uniprot/M0R0Z4> , <https://identifiers.org/uniprot/A0A804HHY0> , <https://identifiers.org/uniprot/H7BZ60> , <https://identifiers.org/uniprot/A0A804HIU5> , <https://identifiers.org/uniprot/P05129> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP363_r138524/DataNode/f5683> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P05129> , <http://purl.uniprot.org/uniprot/A0A804HIU5> , <http://purl.uniprot.org/uniprot/A0A804HHY0> , <http://purl.uniprot.org/uniprot/M0R0Z4> , <http://purl.uniprot.org/uniprot/M0R0I9> , <http://purl.uniprot.org/uniprot/H7BZ60> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/5582> .

<http://rdf.wikipathways.org/Pathway/WP363_r138524/WP/Interaction/d2bd3>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP363_r138524> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP363_r138524/Interaction/d2bd3> ;
        wp:participants   <https://identifiers.org/ncbigene/51701> , <https://identifiers.org/ncbigene/6885> ;
        wp:source         <https://identifiers.org/ncbigene/6885> ;
        wp:target         <https://identifiers.org/ncbigene/51701> .

<https://identifiers.org/pmc/PMC9099719>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed Central" ;
        dcterms:identifier  "PMC9099719" ;
        cito:cites          <https://identifiers.org/wikipathways/WP363> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/PMC9099719> .

<https://identifiers.org/ncbigene/4920>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "ROR2" ;
        dc:identifier       <https://identifiers.org/ncbigene/4920> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "4920" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP363_r138524/WP/Interaction/c568c> , <https://identifiers.org/wikipathways/WP363_r138524> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000169071> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/4920> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/ROR2> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q01974> , <https://identifiers.org/uniprot/B1APY4> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP363_r138524/DataNode/e6b18> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q01974> , <http://purl.uniprot.org/uniprot/B1APY4> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/4920> .

<https://identifiers.org/ncbigene/595>
        rdf:type            wp:Protein , wp:Rna , wp:DataNode ;
        rdfs:label          "CCND1" ;
        dc:identifier       <https://identifiers.org/ncbigene/595> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "595" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP363_r138524/WP/Interaction/id54c4b5ca> , <https://identifiers.org/wikipathways/WP363_r138524> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000110092> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/595> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/CCND1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/F5H437> , <https://identifiers.org/uniprot/Q6FI00> , <https://identifiers.org/uniprot/P24385> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP363_r138524/DataNode/fc042> , <http://rdf.wikipathways.org/Pathway/WP363_r138524/DataNode/c9da8> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P24385> , <http://purl.uniprot.org/uniprot/Q6FI00> , <http://purl.uniprot.org/uniprot/F5H437> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/595> .

<http://rdf.wikipathways.org/Pathway/WP363_r138524/WP/Interaction/id8ec6a684>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP363_r138524> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP363_r138524/Interaction/id8ec6a684> ;
        wp:participants   <https://identifiers.org/ncbigene/4040> , <https://identifiers.org/ncbigene/2932> ;
        wp:source         <https://identifiers.org/ncbigene/2932> ;
        wp:target         <https://identifiers.org/ncbigene/4040> .

<https://identifiers.org/wikipathways/WP363>
        pav:hasVersion  <https://identifiers.org/wikipathways/WP363_r138524> .

<https://identifiers.org/pmc/PMC12593800>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed Central" ;
        dcterms:identifier  "PMC12593800" ;
        cito:cites          <https://identifiers.org/wikipathways/WP363> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/PMC12593800> .

<https://identifiers.org/ncbigene/5879>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "RAC1" ;
        dc:identifier       <https://identifiers.org/ncbigene/5879> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "5879" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP363_r138524/WP/Interaction/f19aa> , <https://identifiers.org/wikipathways/WP363_r138524> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000136238> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/5879> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/RAC1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A4D2P1> , <https://identifiers.org/uniprot/A0A994J4S4> , <https://identifiers.org/uniprot/A0A994J6T1> , <https://identifiers.org/uniprot/P63000> , <https://identifiers.org/uniprot/A4D2P0> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP363_r138524/DataNode/e69f0> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A4D2P0> , <http://purl.uniprot.org/uniprot/A0A994J4S4> , <http://purl.uniprot.org/uniprot/P63000> , <http://purl.uniprot.org/uniprot/A0A994J6T1> , <http://purl.uniprot.org/uniprot/A4D2P1> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/5879> .

<http://rdf.wikipathways.org/Pathway/WP363_r138524/WP/Interaction/b727b>
        rdf:type          wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP363_r138524> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP363_r138524/Interaction/b727b> .

<http://rdf.wikipathways.org/Pathway/WP363_r138524/WP/Interaction/id54c4b5ca>
        rdf:type          wp:TranscriptionTranslation , wp:Interaction , wp:DirectedInteraction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP363_r138524> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP363_r138524/Interaction/id54c4b5ca> , <http://rdf.wikipathways.org/Pathway/WP363_r138524/Interaction/iddace5197> , <http://rdf.wikipathways.org/Pathway/WP363_r138524/Interaction/id665b694d> , <http://rdf.wikipathways.org/Pathway/WP363_r138524/Interaction/id8179ff04> ;
        wp:participants   <https://identifiers.org/ncbigene/8313> , <https://identifiers.org/ncbigene/7010> , <https://identifiers.org/ncbigene/595> , <https://identifiers.org/ncbigene/51176> , <https://identifiers.org/ncbigene/4609> ;
        wp:source         <https://identifiers.org/ncbigene/51176> ;
        wp:target         <https://identifiers.org/ncbigene/595> , <https://identifiers.org/ncbigene/4609> , <https://identifiers.org/ncbigene/8313> , <https://identifiers.org/ncbigene/7010> .

<https://identifiers.org/ncbigene/6259>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "RYK" ;
        dc:identifier       <https://identifiers.org/ncbigene/6259> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "6259" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP363_r138524> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000163785> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/6259> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/RYK> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/H7C4P6> , <https://identifiers.org/uniprot/P34925> , <https://identifiers.org/uniprot/A0A0D9SFZ4> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP363_r138524/DataNode/dd790> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/H7C4P6> , <http://purl.uniprot.org/uniprot/P34925> , <http://purl.uniprot.org/uniprot/A0A0D9SFZ4> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/6259> .

<http://rdf.wikipathways.org/Pathway/WP363_r138524/WP/Interaction/id5e4055e1>
        rdf:type          wp:Interaction , wp:DirectedInteraction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP363_r138524> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP363_r138524/Interaction/id5e4055e1> , <http://rdf.wikipathways.org/Pathway/WP363_r138524/Interaction/id3dea3a62> ;
        wp:participants   <https://identifiers.org/ncbigene/207> , <https://identifiers.org/ncbigene/2932> , <https://identifiers.org/ncbigene/2646> ;
        wp:source         <https://identifiers.org/ncbigene/2646> , <https://identifiers.org/ncbigene/207> ;
        wp:target         <https://identifiers.org/ncbigene/2932> .

<http://rdf.wikipathways.org/Pathway/WP363_r138524/WP/Interaction/id822d66cd>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP363_r138524> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP363_r138524/Interaction/id822d66cd> ;
        wp:participants   <https://identifiers.org/ncbigene/207> , <https://identifiers.org/ncbigene/2646> ;
        wp:source         <https://identifiers.org/ncbigene/2646> ;
        wp:target         <https://identifiers.org/ncbigene/207> .

<http://rdf.wikipathways.org/Pathway/WP363_r138524/WP/Interaction/a0280>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP363_r138524> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP363_r138524/Interaction/a0280> ;
        wp:participants   <https://identifiers.org/ncbigene/10023> , <https://identifiers.org/ncbigene/1855> ;
        wp:source         <https://identifiers.org/ncbigene/1855> ;
        wp:target         <https://identifiers.org/ncbigene/10023> .

<https://identifiers.org/ncbigene/1855>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "DVL1" ;
        dc:identifier       <https://identifiers.org/ncbigene/1855> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "1855" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP363_r138524/WP/Interaction/c5361> , <http://rdf.wikipathways.org/Pathway/WP363_r138524/WP/Interaction/idb34c43b2> , <http://rdf.wikipathways.org/Pathway/WP363_r138524/WP/Interaction/idb7fc1a36> , <https://identifiers.org/wikipathways/WP363_r138524> , <http://rdf.wikipathways.org/Pathway/WP363_r138524/WP/Interaction/f19aa> , <http://rdf.wikipathways.org/Pathway/WP363_r138524/WP/Interaction/a0280> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000107404> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/1855> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/DVL1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A0J9YWZ5> , <https://identifiers.org/uniprot/A0A0J9YYK1> , <https://identifiers.org/uniprot/O14640> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP363_r138524/DataNode/ea1bd> , <http://rdf.wikipathways.org/Pathway/WP363_r138524/DataNode/b8b23> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A0J9YYK1> , <http://purl.uniprot.org/uniprot/O14640> , <http://purl.uniprot.org/uniprot/A0A0J9YWZ5> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/1855> .

<http://rdf.wikipathways.org/Pathway/WP363_r138524/WP/Interaction/b3fef>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP363_r138524> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP363_r138524/Interaction/b3fef> ;
        wp:participants   <https://identifiers.org/ncbigene/7248> , <https://identifiers.org/ncbigene/1856> ;
        wp:source         <https://identifiers.org/ncbigene/1856> ;
        wp:target         <https://identifiers.org/ncbigene/7248> .

<https://identifiers.org/pmc/PMC12301734>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed Central" ;
        dcterms:identifier  "PMC12301734" ;
        cito:cites          <https://identifiers.org/wikipathways/WP363> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/PMC12301734> .

<https://identifiers.org/ncbigene/5594>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "MAPK1" ;
        dc:identifier       <https://identifiers.org/ncbigene/5594> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "5594" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP363_r138524/WP/Interaction/bef9d> , <https://identifiers.org/wikipathways/WP363_r138524> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000100030> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/5594> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/MAPK1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q1HBJ4> , <https://identifiers.org/uniprot/P28482> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP363_r138524/DataNode/a5914> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P28482> , <http://purl.uniprot.org/uniprot/Q1HBJ4> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/5594> .

<https://identifiers.org/ncbigene/387>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "RHOA" ;
        dc:identifier       <https://identifiers.org/ncbigene/387> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "387" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP363_r138524> , <http://rdf.wikipathways.org/Pathway/WP363_r138524/WP/Interaction/e9469> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000067560> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/387> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/RHOA> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/C9JRM1> , <https://identifiers.org/uniprot/A0A7I2V5E6> , <https://identifiers.org/uniprot/C9JX21> , <https://identifiers.org/uniprot/C9JNR4> , <https://identifiers.org/uniprot/A0A7I2V3G1> , <https://identifiers.org/uniprot/A0A7I2YQV1> , <https://identifiers.org/uniprot/P61586> , <https://identifiers.org/uniprot/A0A024R324> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP363_r138524/DataNode/b9efd> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A024R324> , <http://purl.uniprot.org/uniprot/A0A7I2YQV1> , <http://purl.uniprot.org/uniprot/C9JNR4> , <http://purl.uniprot.org/uniprot/A0A7I2V3G1> , <http://purl.uniprot.org/uniprot/P61586> , <http://purl.uniprot.org/uniprot/C9JX21> , <http://purl.uniprot.org/uniprot/A0A7I2V5E6> , <http://purl.uniprot.org/uniprot/C9JRM1> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/387> .

<https://identifiers.org/ncbigene/5579>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "PRKCB" ;
        dc:identifier       <https://identifiers.org/ncbigene/5579> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "5579" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP363_r138524> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000166501> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/5579> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/PRKCB> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/I3L148> , <https://identifiers.org/uniprot/I3L1Z0> , <https://identifiers.org/uniprot/H3BV73> , <https://identifiers.org/uniprot/P05771> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP363_r138524/DataNode/ecf5a> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/I3L148> , <http://purl.uniprot.org/uniprot/I3L1Z0> , <http://purl.uniprot.org/uniprot/P05771> , <http://purl.uniprot.org/uniprot/H3BV73> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/5579> .

<https://identifiers.org/ncbigene/6929>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "TCF3" ;
        dc:identifier       <https://identifiers.org/ncbigene/6929> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "6929" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP363_r138524> , <http://rdf.wikipathways.org/Pathway/WP363_r138524/WP/Interaction/a89cf> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000071564> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/6929> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/TCF3> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/K7ELF3> , <https://identifiers.org/uniprot/K7EPH6> , <https://identifiers.org/uniprot/A0A994J7B2> , <https://identifiers.org/uniprot/K7ERZ7> , <https://identifiers.org/uniprot/K7EPS2> , <https://identifiers.org/uniprot/X6REB3> , <https://identifiers.org/uniprot/A0A494C1R3> , <https://identifiers.org/uniprot/K7EK65> , <https://identifiers.org/uniprot/A0A0A0MTS0> , <https://identifiers.org/uniprot/K7EKB9> , <https://identifiers.org/uniprot/K7EMM4> , <https://identifiers.org/uniprot/K7ENI0> , <https://identifiers.org/uniprot/K7ENH8> , <https://identifiers.org/uniprot/K7EJN4> , <https://identifiers.org/uniprot/P15923> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP363_r138524/DataNode/b0138> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/K7ERZ7> , <http://purl.uniprot.org/uniprot/K7ENH8> , <http://purl.uniprot.org/uniprot/K7EMM4> , <http://purl.uniprot.org/uniprot/K7EPH6> , <http://purl.uniprot.org/uniprot/K7EJN4> , <http://purl.uniprot.org/uniprot/K7EK65> , <http://purl.uniprot.org/uniprot/A0A0A0MTS0> , <http://purl.uniprot.org/uniprot/K7EPS2> , <http://purl.uniprot.org/uniprot/A0A494C1R3> , <http://purl.uniprot.org/uniprot/A0A994J7B2> , <http://purl.uniprot.org/uniprot/K7ELF3> , <http://purl.uniprot.org/uniprot/K7EKB9> , <http://purl.uniprot.org/uniprot/K7ENI0> , <http://purl.uniprot.org/uniprot/X6REB3> , <http://purl.uniprot.org/uniprot/P15923> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/6929> .

obo:NCBITaxon_9606  obo:NCIT_C179773  "9606" .

<https://identifiers.org/ncbigene/6885>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "MAP3K7" ;
        dc:identifier       <https://identifiers.org/ncbigene/6885> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "6885" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP363_r138524> , <http://rdf.wikipathways.org/Pathway/WP363_r138524/WP/Interaction/d2bd3> , <http://rdf.wikipathways.org/Pathway/WP363_r138524/WP/Interaction/d5f45> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000135341> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/6885> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/MAP3K7> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A8V8TQ28> , <https://identifiers.org/uniprot/A0A8V8TQL7> , <https://identifiers.org/uniprot/A0A8V8TRC6> , <https://identifiers.org/uniprot/A0A8V8TPV8> , <https://identifiers.org/uniprot/A0A8V8TR17> , <https://identifiers.org/uniprot/A0A8V8TQF8> , <https://identifiers.org/uniprot/A0A8V8TRC0> , <https://identifiers.org/uniprot/A0A8V8TQE8> , <https://identifiers.org/uniprot/A0A8V8TRC2> , <https://identifiers.org/uniprot/A0A8V8TQF2> , <https://identifiers.org/uniprot/A0A8V8TQF4> , <https://identifiers.org/uniprot/A0A8V8TR14> , <https://identifiers.org/uniprot/A0A8V8TPW3> , <https://identifiers.org/uniprot/O43318> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP363_r138524/DataNode/e10c1> , <http://rdf.wikipathways.org/Pathway/WP363_r138524/DataNode/fac5d> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A8V8TQF2> , <http://purl.uniprot.org/uniprot/A0A8V8TQE8> , <http://purl.uniprot.org/uniprot/A0A8V8TQF4> , <http://purl.uniprot.org/uniprot/A0A8V8TRC6> , <http://purl.uniprot.org/uniprot/A0A8V8TR17> , <http://purl.uniprot.org/uniprot/A0A8V8TRC2> , <http://purl.uniprot.org/uniprot/O43318> , <http://purl.uniprot.org/uniprot/A0A8V8TR14> , <http://purl.uniprot.org/uniprot/A0A8V8TQF8> , <http://purl.uniprot.org/uniprot/A0A8V8TQL7> , <http://purl.uniprot.org/uniprot/A0A8V8TRC0> , <http://purl.uniprot.org/uniprot/A0A8V8TPW3> , <http://purl.uniprot.org/uniprot/A0A8V8TPV8> , <http://purl.uniprot.org/uniprot/A0A8V8TQ28> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/6885> .

<http://rdf.wikipathways.org/Pathway/WP363_r138524/WP/Interaction/d8911>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP363_r138524> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP363_r138524/Interaction/d8911> ;
        wp:participants   <https://identifiers.org/ncbigene/1499> ;
        wp:source         <https://identifiers.org/ncbigene/1499> ;
        wp:target         <https://identifiers.org/ncbigene/1499> .

<http://rdf.wikipathways.org/Pathway/WP363_r138524/WP/Interaction/id981e0eb5>
        rdf:type          wp:Inhibition , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP363_r138524> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP363_r138524/Interaction/id981e0eb5> ;
        wp:participants   <https://identifiers.org/ncbigene/2475> , <https://identifiers.org/ncbigene/7249> ;
        wp:source         <https://identifiers.org/ncbigene/7249> ;
        wp:target         <https://identifiers.org/ncbigene/2475> .

<https://identifiers.org/ncbigene/4041>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "LRP5" ;
        dc:identifier       <https://identifiers.org/ncbigene/4041> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "4041" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP363_r138524> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000162337> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/4041> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/LRP5> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/O75197> , <https://identifiers.org/uniprot/E9PHY1> , <https://identifiers.org/uniprot/H0YE98> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP363_r138524/DataNode/e4f9c> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/E9PHY1> , <http://purl.uniprot.org/uniprot/O75197> , <http://purl.uniprot.org/uniprot/H0YE98> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/4041> .

<http://rdf.wikipathways.org/Pathway/WP363_r138524/WP/Interaction/id64d620d6>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP363_r138524> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP363_r138524/Interaction/id64d620d6> ;
        wp:participants   <https://identifiers.org/ncbigene/7248> , <https://identifiers.org/ncbigene/2932> ;
        wp:source         <https://identifiers.org/ncbigene/2932> ;
        wp:target         <https://identifiers.org/ncbigene/7248> .

<https://identifiers.org/ncbigene/2475>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "MTOR" ;
        dc:identifier       <https://identifiers.org/ncbigene/2475> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "2475" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP363_r138524/WP/Interaction/id981e0eb5> , <https://identifiers.org/wikipathways/WP363_r138524> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000198793> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/2475> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/MTOR> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A8V8TR74> , <https://identifiers.org/uniprot/A0A8V8TQM6> , <https://identifiers.org/uniprot/A0A8V8TRG9> , <https://identifiers.org/uniprot/A0A8V8TQN3> , <https://identifiers.org/uniprot/A0A8V8TQ52> , <https://identifiers.org/uniprot/P42345> , <https://identifiers.org/uniprot/A0A8V8TQP2> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP363_r138524/DataNode/fa78c> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A8V8TQM6> , <http://purl.uniprot.org/uniprot/A0A8V8TQ52> , <http://purl.uniprot.org/uniprot/A0A8V8TQN3> , <http://purl.uniprot.org/uniprot/A0A8V8TR74> , <http://purl.uniprot.org/uniprot/A0A8V8TRG9> , <http://purl.uniprot.org/uniprot/A0A8V8TQP2> , <http://purl.uniprot.org/uniprot/P42345> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/2475> .

<http://rdf.wikipathways.org/Pathway/WP363_r138524/WP/Interaction/a89cf>
        rdf:type          wp:Interaction , wp:DirectedInteraction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP363_r138524> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP363_r138524/Interaction/bc7eb> , <http://rdf.wikipathways.org/Pathway/WP363_r138524/Interaction/acaa4> , <http://rdf.wikipathways.org/Pathway/WP363_r138524/Interaction/b4dd1> , <http://rdf.wikipathways.org/Pathway/WP363_r138524/Interaction/a89cf> , <http://rdf.wikipathways.org/Pathway/WP363_r138524/Interaction/a7117> , <http://rdf.wikipathways.org/Pathway/WP363_r138524/Interaction/e9c45> , <http://rdf.wikipathways.org/Pathway/WP363_r138524/Interaction/ea8ec> , <http://rdf.wikipathways.org/Pathway/WP363_r138524/Interaction/a4aa9> , <http://rdf.wikipathways.org/Pathway/WP363_r138524/Interaction/f8372> ;
        wp:participants   <https://identifiers.org/ncbigene/1021> , <https://identifiers.org/ncbigene/1487> , <https://identifiers.org/ncbigene/6929> , <https://identifiers.org/ncbigene/51176> , <https://identifiers.org/ncbigene/6656> , <https://identifiers.org/ncbigene/6934> , <https://identifiers.org/ncbigene/1499> , <https://identifiers.org/ncbigene/4773> ;
        wp:source         <https://identifiers.org/ncbigene/1499> ;
        wp:target         <https://identifiers.org/ncbigene/6929> , <https://identifiers.org/ncbigene/1487> , <https://identifiers.org/ncbigene/4773> , <https://identifiers.org/ncbigene/6934> , <https://identifiers.org/ncbigene/6656> , <https://identifiers.org/ncbigene/1021> , <https://identifiers.org/ncbigene/51176> .

<https://identifiers.org/ncbigene/5599>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "MAPK8" ;
        dc:identifier       <https://identifiers.org/ncbigene/5599> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "5599" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP363_r138524/WP/Interaction/e9469> , <https://identifiers.org/wikipathways/WP363_r138524> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000107643> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/5599> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/MAPK8> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A3B3IRW7> , <https://identifiers.org/uniprot/C9J762> , <https://identifiers.org/uniprot/A1L4K2> , <https://identifiers.org/uniprot/C9JWQ4> , <https://identifiers.org/uniprot/P45983> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP363_r138524/DataNode/ec02e> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/C9JWQ4> , <http://purl.uniprot.org/uniprot/C9J762> , <http://purl.uniprot.org/uniprot/A0A3B3IRW7> , <http://purl.uniprot.org/uniprot/P45983> , <http://purl.uniprot.org/uniprot/A1L4K2> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/5599> .

<https://identifiers.org/ncbigene/4773>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "NFATC2" ;
        dc:identifier       <https://identifiers.org/ncbigene/4773> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "4773" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP363_r138524/WP/Interaction/a89cf> , <https://identifiers.org/wikipathways/WP363_r138524> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000101096> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/4773> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/NFATC2> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q13469> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP363_r138524/DataNode/f90a1> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q13469> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/4773> .

<http://rdf.wikipathways.org/Pathway/WP363_r138524/WP/Interaction/idaf80b52d>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP363_r138524> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP363_r138524/Interaction/idaf80b52d> ;
        wp:participants   <https://identifiers.org/ncbigene/409> , <https://identifiers.org/ncbigene/1856> ;
        wp:source         <https://identifiers.org/ncbigene/1856> ;
        wp:target         <https://identifiers.org/ncbigene/409> .

<https://identifiers.org/pmc/PMC7425054>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed Central" ;
        dcterms:identifier  "PMC7425054" ;
        cito:cites          <https://identifiers.org/wikipathways/WP363> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/PMC7425054> .

<http://rdf.wikipathways.org/Pathway/WP363_r138524/WP/Interaction/id8f3d1280>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP363_r138524> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP363_r138524/Interaction/id8f3d1280> ;
        wp:participants   <https://identifiers.org/ncbigene/1856> , <https://identifiers.org/ncbigene/8312> ;
        wp:source         <https://identifiers.org/ncbigene/8312> ;
        wp:target         <https://identifiers.org/ncbigene/1856> .

<https://identifiers.org/ncbigene/5578>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "PRKCA" ;
        dc:identifier       <https://identifiers.org/ncbigene/5578> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "5578" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP363_r138524/WP/Interaction/b21d1> , <https://identifiers.org/wikipathways/WP363_r138524> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000154229> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/5578> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/PRKCA> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/L7RSM7> , <https://identifiers.org/uniprot/J3KN97> , <https://identifiers.org/uniprot/P17252> , <https://identifiers.org/uniprot/J3KRN5> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP363_r138524/DataNode/d9e4d> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P17252> , <http://purl.uniprot.org/uniprot/J3KRN5> , <http://purl.uniprot.org/uniprot/J3KN97> , <http://purl.uniprot.org/uniprot/L7RSM7> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/5578> .

<https://identifiers.org/ncbigene/2646>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "GCKR" ;
        dc:identifier       <https://identifiers.org/ncbigene/2646> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "2646" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP363_r138524> , <http://rdf.wikipathways.org/Pathway/WP363_r138524/WP/Interaction/id5e4055e1> , <http://rdf.wikipathways.org/Pathway/WP363_r138524/WP/Interaction/c5361> , <http://rdf.wikipathways.org/Pathway/WP363_r138524/WP/Interaction/id822d66cd> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000084734> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/2646> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/GCKR> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A0C4DFN2> , <https://identifiers.org/uniprot/H7C1B4> , <https://identifiers.org/uniprot/H7C4D3> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP363_r138524/DataNode/b071d> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/H7C1B4> , <http://purl.uniprot.org/uniprot/A0A0C4DFN2> , <http://purl.uniprot.org/uniprot/H7C4D3> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/2646> .

<https://identifiers.org/ncbigene/55361>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "PI4K2A" ;
        dc:identifier       <https://identifiers.org/ncbigene/55361> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "55361" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP363_r138524> , <http://rdf.wikipathways.org/Pathway/WP363_r138524/WP/Interaction/c568c> , <http://rdf.wikipathways.org/Pathway/WP363_r138524/WP/Interaction/idb34c43b2> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000155252> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/55361> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/PI4K2A> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q9BTU6> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP363_r138524/DataNode/ced58> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q9BTU6> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/55361> .

<https://identifiers.org/ncbigene/51701>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "NLK" ;
        dc:identifier       <https://identifiers.org/ncbigene/51701> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "51701" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP363_r138524/WP/Interaction/f77df> , <https://identifiers.org/wikipathways/WP363_r138524> , <http://rdf.wikipathways.org/Pathway/WP363_r138524/WP/Interaction/d2bd3> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000087095> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/51701> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/NLK> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q9UBE8> , <https://identifiers.org/uniprot/H0YD75> , <https://identifiers.org/uniprot/J3QSE9> , <https://identifiers.org/uniprot/A0A024QZ12> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP363_r138524/DataNode/e929f> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/H0YD75> , <http://purl.uniprot.org/uniprot/A0A024QZ12> , <http://purl.uniprot.org/uniprot/Q9UBE8> , <http://purl.uniprot.org/uniprot/J3QSE9> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/51701> .

<https://identifiers.org/ncbigene/409>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "ARRB2" ;
        dc:identifier       <https://identifiers.org/ncbigene/409> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "409" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP363_r138524> , <http://rdf.wikipathways.org/Pathway/WP363_r138524/WP/Interaction/idaf80b52d> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000141480> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/409> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/ARRB2> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/K7EL17> , <https://identifiers.org/uniprot/Q68DZ5> , <https://identifiers.org/uniprot/K7ENA6> , <https://identifiers.org/uniprot/P32121> , <https://identifiers.org/uniprot/I3L412> , <https://identifiers.org/uniprot/I3L0V6> , <https://identifiers.org/uniprot/I3L1M6> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP363_r138524/DataNode/adf5e> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/I3L412> , <http://purl.uniprot.org/uniprot/K7ENA6> , <http://purl.uniprot.org/uniprot/I3L0V6> , <http://purl.uniprot.org/uniprot/I3L1M6> , <http://purl.uniprot.org/uniprot/K7EL17> , <http://purl.uniprot.org/uniprot/P32121> , <http://purl.uniprot.org/uniprot/Q68DZ5> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/409> .

<https://identifiers.org/ncbigene/2932>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "GSK3B" ;
        dc:identifier       <https://identifiers.org/ncbigene/2932> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "2932" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP363_r138524> , <http://rdf.wikipathways.org/Pathway/WP363_r138524/WP/Interaction/id64d620d6> , <http://rdf.wikipathways.org/Pathway/WP363_r138524/WP/Interaction/id8ec6a684> , <http://rdf.wikipathways.org/Pathway/WP363_r138524/WP/Interaction/id5e4055e1> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000082701> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/2932> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/GSK3B> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A7I2V4G2> , <https://identifiers.org/uniprot/A0A7I2V675> , <https://identifiers.org/uniprot/A0A7I2V2V4> , <https://identifiers.org/uniprot/A0A7I2V3K8> , <https://identifiers.org/uniprot/Q6FI27> , <https://identifiers.org/uniprot/A0A7I2V4X2> , <https://identifiers.org/uniprot/A0A7I2YQK2> , <https://identifiers.org/uniprot/A0A7I2YQG6> , <https://identifiers.org/uniprot/P49841> , <https://identifiers.org/uniprot/A0A7I2V441> , <https://identifiers.org/uniprot/A0A7I2V589> , <https://identifiers.org/uniprot/A0A7I2V606> , <https://identifiers.org/uniprot/A0A7I2V2I5> , <https://identifiers.org/uniprot/A0A7I2V3T3> , <https://identifiers.org/uniprot/A0A7I2YQ81> , <https://identifiers.org/uniprot/A0A7I2V3D8> , <https://identifiers.org/uniprot/A0A7I2YQU1> , <https://identifiers.org/uniprot/A0A7I2V2U4> , <https://identifiers.org/uniprot/A0A7I2V5M2> , <https://identifiers.org/uniprot/A0A7I2V3G9> , <https://identifiers.org/uniprot/A0A7I2V3Z5> , <https://identifiers.org/uniprot/A0A7I2YQB0> , <https://identifiers.org/uniprot/A0A7I2V5K9> , <https://identifiers.org/uniprot/A0A7I2V2Y0> , <https://identifiers.org/uniprot/A0A7I2V2T2> , <https://identifiers.org/uniprot/A0A7I2V5P4> , <https://identifiers.org/uniprot/A0A7I2V626> , <https://identifiers.org/uniprot/A0A7I2V432> , <https://identifiers.org/uniprot/A0A7I2V3A4> , <https://identifiers.org/uniprot/A0A7I2V2N4> , <https://identifiers.org/uniprot/A0A7I2V3S5> , <https://identifiers.org/uniprot/A0A7I2V3N7> , <https://identifiers.org/uniprot/A0A7I2V4X3> , <https://identifiers.org/uniprot/A0A7I2V4F3> , <https://identifiers.org/uniprot/A0A7I2V5G5> , <https://identifiers.org/uniprot/A0A7I2V4W7> , <https://identifiers.org/uniprot/A0A7I2V2K7> , <https://identifiers.org/uniprot/A0A7I2V5B5> , <https://identifiers.org/uniprot/A0A3B3ITW1> , <https://identifiers.org/uniprot/A0A7I2YQK0> , <https://identifiers.org/uniprot/A0A7I2V3J4> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP363_r138524/DataNode/a9963> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A7I2V4X3> , <http://purl.uniprot.org/uniprot/A0A7I2V5K9> , <http://purl.uniprot.org/uniprot/Q6FI27> , <http://purl.uniprot.org/uniprot/A0A7I2YQU1> , <http://purl.uniprot.org/uniprot/A0A7I2V3G9> , <http://purl.uniprot.org/uniprot/A0A7I2V3S5> , <http://purl.uniprot.org/uniprot/A0A7I2V2U4> , <http://purl.uniprot.org/uniprot/A0A7I2V626> , <http://purl.uniprot.org/uniprot/A0A7I2V5B5> , <http://purl.uniprot.org/uniprot/A0A7I2V4F3> , <http://purl.uniprot.org/uniprot/A0A7I2V3D8> , <http://purl.uniprot.org/uniprot/A0A7I2V432> , <http://purl.uniprot.org/uniprot/A0A7I2V4G2> , <http://purl.uniprot.org/uniprot/A0A7I2YQB0> , <http://purl.uniprot.org/uniprot/A0A7I2V4X2> , <http://purl.uniprot.org/uniprot/A0A7I2V2I5> , <http://purl.uniprot.org/uniprot/A0A7I2V606> , <http://purl.uniprot.org/uniprot/A0A7I2V3K8> , <http://purl.uniprot.org/uniprot/P49841> , <http://purl.uniprot.org/uniprot/A0A7I2YQK2> , <http://purl.uniprot.org/uniprot/A0A7I2V675> , <http://purl.uniprot.org/uniprot/A0A7I2YQG6> , <http://purl.uniprot.org/uniprot/A0A7I2V5G5> , <http://purl.uniprot.org/uniprot/A0A7I2V4W7> , <http://purl.uniprot.org/uniprot/A0A7I2YQ81> , <http://purl.uniprot.org/uniprot/A0A7I2V3A4> , <http://purl.uniprot.org/uniprot/A0A7I2V3Z5> , <http://purl.uniprot.org/uniprot/A0A7I2V5M2> , <http://purl.uniprot.org/uniprot/A0A7I2V2N4> , <http://purl.uniprot.org/uniprot/A0A7I2V3T3> , <http://purl.uniprot.org/uniprot/A0A7I2V3J4> , <http://purl.uniprot.org/uniprot/A0A7I2YQK0> , <http://purl.uniprot.org/uniprot/A0A7I2V2T2> , <http://purl.uniprot.org/uniprot/A0A7I2V5P4> , <http://purl.uniprot.org/uniprot/A0A3B3ITW1> , <http://purl.uniprot.org/uniprot/A0A7I2V2V4> , <http://purl.uniprot.org/uniprot/A0A7I2V2K7> , <http://purl.uniprot.org/uniprot/A0A7I2V589> , <http://purl.uniprot.org/uniprot/A0A7I2V2Y0> , <http://purl.uniprot.org/uniprot/A0A7I2V441> , <http://purl.uniprot.org/uniprot/A0A7I2V3N7> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/2932> .

<https://identifiers.org/ncbigene/4040>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "LRP6" ;
        dc:identifier       <https://identifiers.org/ncbigene/4040> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "4040" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP363_r138524/WP/Interaction/id8ec6a684> , <https://identifiers.org/wikipathways/WP363_r138524> , <http://rdf.wikipathways.org/Pathway/WP363_r138524/WP/Interaction/idb7fc1a36> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000070018> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/4040> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/LRP6> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/H0YGH0> , <https://identifiers.org/uniprot/F5H0Z3> , <https://identifiers.org/uniprot/O75581> , <https://identifiers.org/uniprot/H0YGW5> , <https://identifiers.org/uniprot/F5H7J9> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP363_r138524/DataNode/bfefe> , <http://rdf.wikipathways.org/Pathway/WP363_r138524/DataNode/a41ec> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/O75581> , <http://purl.uniprot.org/uniprot/F5H0Z3> , <http://purl.uniprot.org/uniprot/H0YGH0> , <http://purl.uniprot.org/uniprot/F5H7J9> , <http://purl.uniprot.org/uniprot/H0YGW5> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/4040> .

<https://identifiers.org/ncbigene/324>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "APC" ;
        dc:identifier       <https://identifiers.org/ncbigene/324> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "324" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP363_r138524> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000134982> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/324> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/APC> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/E9PFT7> , <https://identifiers.org/uniprot/E7EMH9> , <https://identifiers.org/uniprot/A0A087X2F3> , <https://identifiers.org/uniprot/A0A087WYF3> , <https://identifiers.org/uniprot/D6RFL6> , <https://identifiers.org/uniprot/A0A2Q2SV78> , <https://identifiers.org/uniprot/P25054> , <https://identifiers.org/uniprot/R4GMU6> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP363_r138524/DataNode/d2cc1> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A087WYF3> , <http://purl.uniprot.org/uniprot/A0A087X2F3> , <http://purl.uniprot.org/uniprot/D6RFL6> , <http://purl.uniprot.org/uniprot/E7EMH9> , <http://purl.uniprot.org/uniprot/P25054> , <http://purl.uniprot.org/uniprot/A0A2Q2SV78> , <http://purl.uniprot.org/uniprot/R4GMU6> , <http://purl.uniprot.org/uniprot/E9PFT7> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/324> .

<http://rdf.wikipathways.org/Pathway/WP363_r138524/WP/Interaction/c5361>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP363_r138524> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP363_r138524/Interaction/c5361> ;
        wp:participants   <https://identifiers.org/ncbigene/2646> , <https://identifiers.org/ncbigene/1855> ;
        wp:source         <https://identifiers.org/ncbigene/1855> ;
        wp:target         <https://identifiers.org/ncbigene/2646> .

<https://identifiers.org/ncbigene/7249>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "TSC2" ;
        dc:identifier       <https://identifiers.org/ncbigene/7249> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "7249" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP363_r138524/WP/Interaction/id981e0eb5> , <https://identifiers.org/wikipathways/WP363_r138524> , <http://rdf.wikipathways.org/Pathway/WP363_r138524/WP/Interaction/ed855> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000103197> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/7249> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/TSC2> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/H3BQK4> , <https://identifiers.org/uniprot/A0A2R8Y7X5> , <https://identifiers.org/uniprot/I3L3B1> , <https://identifiers.org/uniprot/A0A2R8YDZ2> , <https://identifiers.org/uniprot/Q5HYF7> , <https://identifiers.org/uniprot/A0A2R8YGE6> , <https://identifiers.org/uniprot/A0A2R8Y692> , <https://identifiers.org/uniprot/I3L134> , <https://identifiers.org/uniprot/A0A2R8Y6C9> , <https://identifiers.org/uniprot/P49815> , <https://identifiers.org/uniprot/A0A2R8Y5B2> , <https://identifiers.org/uniprot/A0A2R8Y7C8> , <https://identifiers.org/uniprot/A0A2R8Y670> , <https://identifiers.org/uniprot/A0A2R8YGD6> , <https://identifiers.org/uniprot/H3BQY7> , <https://identifiers.org/uniprot/A0A2R8YHA2> , <https://identifiers.org/uniprot/A0A2R8YGU4> , <https://identifiers.org/uniprot/A0A2R8YEJ8> , <https://identifiers.org/uniprot/A0A2R8Y5F1> , <https://identifiers.org/uniprot/X5D7Q2> , <https://identifiers.org/uniprot/X5D2U8> , <https://identifiers.org/uniprot/A0A2R8YCR8> , <https://identifiers.org/uniprot/A0A2R8YDR3> , <https://identifiers.org/uniprot/H3BMQ0> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP363_r138524/DataNode/b0d1f> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A2R8Y692> , <http://purl.uniprot.org/uniprot/A0A2R8YCR8> , <http://purl.uniprot.org/uniprot/H3BMQ0> , <http://purl.uniprot.org/uniprot/A0A2R8Y7X5> , <http://purl.uniprot.org/uniprot/A0A2R8YHA2> , <http://purl.uniprot.org/uniprot/A0A2R8YGU4> , <http://purl.uniprot.org/uniprot/A0A2R8Y5B2> , <http://purl.uniprot.org/uniprot/A0A2R8Y5F1> , <http://purl.uniprot.org/uniprot/A0A2R8YDR3> , <http://purl.uniprot.org/uniprot/A0A2R8YGD6> , <http://purl.uniprot.org/uniprot/H3BQK4> , <http://purl.uniprot.org/uniprot/I3L3B1> , <http://purl.uniprot.org/uniprot/A0A2R8Y7C8> , <http://purl.uniprot.org/uniprot/Q5HYF7> , <http://purl.uniprot.org/uniprot/P49815> , <http://purl.uniprot.org/uniprot/A0A2R8YGE6> , <http://purl.uniprot.org/uniprot/A0A2R8Y670> , <http://purl.uniprot.org/uniprot/A0A2R8YDZ2> , <http://purl.uniprot.org/uniprot/A0A2R8Y6C9> , <http://purl.uniprot.org/uniprot/X5D7Q2> , <http://purl.uniprot.org/uniprot/A0A2R8YEJ8> , <http://purl.uniprot.org/uniprot/H3BQY7> , <http://purl.uniprot.org/uniprot/X5D2U8> , <http://purl.uniprot.org/uniprot/I3L134> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/7249> .

<https://identifiers.org/ncbigene/4609>
        rdf:type            wp:Rna , wp:DataNode ;
        rdfs:label          "MYC" ;
        dc:identifier       <https://identifiers.org/ncbigene/4609> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "4609" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP363_r138524> , <http://rdf.wikipathways.org/Pathway/WP363_r138524/WP/Interaction/id54c4b5ca> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000136997> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/4609> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/MYC> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/P01106> , <https://identifiers.org/uniprot/Q14899> , <https://identifiers.org/uniprot/A0A494C1T8> , <https://identifiers.org/uniprot/Q16591> , <https://identifiers.org/uniprot/A0A0B4J1R1> , <https://identifiers.org/uniprot/H0YBG3> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP363_r138524/DataNode/c7ee3> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P01106> , <http://purl.uniprot.org/uniprot/A0A0B4J1R1> , <http://purl.uniprot.org/uniprot/Q16591> , <http://purl.uniprot.org/uniprot/Q14899> , <http://purl.uniprot.org/uniprot/H0YBG3> , <http://purl.uniprot.org/uniprot/A0A494C1T8> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/4609> .

<http://rdf.wikipathways.org/Pathway/WP363_r138524/WP/Interaction/bb3cf>
        rdf:type          wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP363_r138524> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP363_r138524/Interaction/bb3cf> .

<https://identifiers.org/ncbigene/7010>
        rdf:type            wp:DataNode , wp:Rna ;
        rdfs:label          "TEK" ;
        dc:identifier       <https://identifiers.org/ncbigene/7010> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "7010" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP363_r138524/WP/Interaction/id54c4b5ca> , <https://identifiers.org/wikipathways/WP363_r138524> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000120156> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/7010> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/TEK> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/E5RIV9> , <https://identifiers.org/uniprot/B5A954> , <https://identifiers.org/uniprot/Q02763> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP363_r138524/DataNode/ca6bd> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q02763> , <http://purl.uniprot.org/uniprot/B5A954> , <http://purl.uniprot.org/uniprot/E5RIV9> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/7010> .

<https://identifiers.org/pmc/PMC8743585>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed Central" ;
        dcterms:identifier  "PMC8743585" ;
        cito:cites          <https://identifiers.org/wikipathways/WP363> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/PMC8743585> .

<https://identifiers.org/ncbigene/1454>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "CSNK1E" ;
        dc:identifier       <https://identifiers.org/ncbigene/1454> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "1454" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP363_r138524> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000213923> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/1454> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/CSNK1E> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/B0QY36> , <https://identifiers.org/uniprot/B0QY35> , <https://identifiers.org/uniprot/P49674> , <https://identifiers.org/uniprot/H7C3J2> , <https://identifiers.org/uniprot/H0Y5S9> , <https://identifiers.org/uniprot/B0QY34> , <https://identifiers.org/uniprot/H0Y682> , <https://identifiers.org/uniprot/A0A669KBC0> , <https://identifiers.org/uniprot/H0Y645> , <https://identifiers.org/uniprot/Q5U045> , <https://identifiers.org/uniprot/H7C0Y5> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP363_r138524/DataNode/ab67c> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/H7C0Y5> , <http://purl.uniprot.org/uniprot/H0Y682> , <http://purl.uniprot.org/uniprot/H0Y5S9> , <http://purl.uniprot.org/uniprot/B0QY35> , <http://purl.uniprot.org/uniprot/H0Y645> , <http://purl.uniprot.org/uniprot/Q5U045> , <http://purl.uniprot.org/uniprot/H7C3J2> , <http://purl.uniprot.org/uniprot/B0QY36> , <http://purl.uniprot.org/uniprot/P49674> , <http://purl.uniprot.org/uniprot/A0A669KBC0> , <http://purl.uniprot.org/uniprot/B0QY34> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/1454> .

<https://identifiers.org/ncbigene/10023>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "FRAT1" ;
        dc:identifier       <https://identifiers.org/ncbigene/10023> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "10023" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP363_r138524> , <http://rdf.wikipathways.org/Pathway/WP363_r138524/WP/Interaction/idde943844> , <http://rdf.wikipathways.org/Pathway/WP363_r138524/WP/Interaction/a0280> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000165879> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/10023> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/FRAT1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q92837> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP363_r138524/DataNode/a3709> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q92837> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/10023> .

<http://rdf.wikipathways.org/Pathway/WP363_r138524/WP/Interaction/ed855>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP363_r138524> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP363_r138524/Interaction/ed855> ;
        wp:participants   <https://identifiers.org/ncbigene/7249> , <https://identifiers.org/ncbigene/7248> ;
        wp:source         <https://identifiers.org/ncbigene/7248> ;
        wp:target         <https://identifiers.org/ncbigene/7249> .

<https://identifiers.org/ncbigene/6656>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "SOX1" ;
        dc:identifier       <https://identifiers.org/ncbigene/6656> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "6656" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP363_r138524> , <http://rdf.wikipathways.org/Pathway/WP363_r138524/WP/Interaction/a89cf> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000182968> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/6656> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/SOX1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/O00570> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP363_r138524/DataNode/fe152> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/O00570> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/6656> .

<https://identifiers.org/ncbigene/1021>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "CDK6" ;
        dc:identifier       <https://identifiers.org/ncbigene/1021> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "1021" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP363_r138524/WP/Interaction/a89cf> , <https://identifiers.org/wikipathways/WP363_r138524> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000105810> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/1021> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/CDK6> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q00534> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP363_r138524/DataNode/d45c4> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q00534> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/1021> .

<https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=png&pwTitle=Pathway:WP363&oldid=138524>
        rdf:type        foaf:Image ;
        dcterms:format  "image/png" .

<https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=svg&pwTitle=Pathway:WP363&oldid=138524>
        rdf:type        foaf:Image ;
        dcterms:format  "image/svg+xml" .

<http://rdf.wikipathways.org/Pathway/WP363_r138524/WP/Interaction/idb34c43b2>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP363_r138524> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP363_r138524/Interaction/idb34c43b2> ;
        wp:participants   <https://identifiers.org/ncbigene/55361> , <https://identifiers.org/ncbigene/1855> ;
        wp:source         <https://identifiers.org/ncbigene/1855> ;
        wp:target         <https://identifiers.org/ncbigene/55361> .

<https://identifiers.org/ncbigene/1487>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "CTBP1" ;
        dc:identifier       <https://identifiers.org/ncbigene/1487> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "1487" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP363_r138524> , <http://rdf.wikipathways.org/Pathway/WP363_r138524/WP/Interaction/a89cf> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000159692> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/1487> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/CTBP1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q13363> , <https://identifiers.org/uniprot/E9PGB1> , <https://identifiers.org/uniprot/H0Y9M9> , <https://identifiers.org/uniprot/H0Y8W7> , <https://identifiers.org/uniprot/D6RAX2> , <https://identifiers.org/uniprot/H0Y913> , <https://identifiers.org/uniprot/X5D8Y5> , <https://identifiers.org/uniprot/E7ESU7> , <https://identifiers.org/uniprot/H0Y8U5> , <https://identifiers.org/uniprot/E7EUB3> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP363_r138524/DataNode/c26d7> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/H0Y8W7> , <http://purl.uniprot.org/uniprot/D6RAX2> , <http://purl.uniprot.org/uniprot/E7ESU7> , <http://purl.uniprot.org/uniprot/H0Y913> , <http://purl.uniprot.org/uniprot/E7EUB3> , <http://purl.uniprot.org/uniprot/H0Y8U5> , <http://purl.uniprot.org/uniprot/H0Y9M9> , <http://purl.uniprot.org/uniprot/X5D8Y5> , <http://purl.uniprot.org/uniprot/Q13363> , <http://purl.uniprot.org/uniprot/E9PGB1> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/1487> .

<https://identifiers.org/ncbigene/51176>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "LEF1" ;
        dc:identifier       <https://identifiers.org/ncbigene/51176> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "51176" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP363_r138524/WP/Interaction/a89cf> , <http://rdf.wikipathways.org/Pathway/WP363_r138524/WP/Interaction/id54c4b5ca> , <https://identifiers.org/wikipathways/WP363_r138524> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000138795> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/51176> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/LEF1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/D6RAB1> , <https://identifiers.org/uniprot/Q9UJU2> , <https://identifiers.org/uniprot/D6RIV1> , <https://identifiers.org/uniprot/D6RID7> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP363_r138524/DataNode/c22ad> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q9UJU2> , <http://purl.uniprot.org/uniprot/D6RAB1> , <http://purl.uniprot.org/uniprot/D6RID7> , <http://purl.uniprot.org/uniprot/D6RIV1> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/51176> .

<http://rdf.wikipathways.org/Pathway/WP363_r138524/WP/Interaction/e3b70>
        rdf:type          wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP363_r138524> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP363_r138524/Interaction/e3b70> .

<https://identifiers.org/ncbigene/2931>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "GSK3A" ;
        dc:identifier       <https://identifiers.org/ncbigene/2931> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "2931" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP363_r138524> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000105723> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/2931> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/GSK3A> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A024R0L5> , <https://identifiers.org/uniprot/A8MT37> , <https://identifiers.org/uniprot/A0A7I2V511> , <https://identifiers.org/uniprot/A0A7I2V418> , <https://identifiers.org/uniprot/A0A7I2V5B3> , <https://identifiers.org/uniprot/A0A7I2V379> , <https://identifiers.org/uniprot/A0A7I2YQV9> , <https://identifiers.org/uniprot/A0A7I2V341> , <https://identifiers.org/uniprot/A0A7I2V2J2> , <https://identifiers.org/uniprot/A0A7I2YQJ1> , <https://identifiers.org/uniprot/A0A7I2V4D4> , <https://identifiers.org/uniprot/A0A7I2V2H8> , <https://identifiers.org/uniprot/A0A7I2V2P9> , <https://identifiers.org/uniprot/A0A7I2V3W5> , <https://identifiers.org/uniprot/A0A7I2V485> , <https://identifiers.org/uniprot/A0A7I2V4Q6> , <https://identifiers.org/uniprot/A0A7I2YQU7> , <https://identifiers.org/uniprot/A0A7I2V5D7> , <https://identifiers.org/uniprot/P49840> , <https://identifiers.org/uniprot/A0A7I2V553> , <https://identifiers.org/uniprot/A0A7I2V5S8> , <https://identifiers.org/uniprot/A0A7I2V2P8> , <https://identifiers.org/uniprot/A0A7I2V3H9> , <https://identifiers.org/uniprot/A0A7I2V2Q4> , <https://identifiers.org/uniprot/A0A7I2YQ76> , <https://identifiers.org/uniprot/A0A7I2YQA1> , <https://identifiers.org/uniprot/A0A7I2V627> , <https://identifiers.org/uniprot/A0A7I2V2P0> , <https://identifiers.org/uniprot/A0A7I2YQM8> , <https://identifiers.org/uniprot/A0A7I2YQA9> , <https://identifiers.org/uniprot/A0A7I2V4Z1> , <https://identifiers.org/uniprot/A0A7I2V4Y3> , <https://identifiers.org/uniprot/A0A7I2V3M8> , <https://identifiers.org/uniprot/A0A7I2V5Q2> , <https://identifiers.org/uniprot/A0A7I2V5P6> , <https://identifiers.org/uniprot/A0A7I2V345> , <https://identifiers.org/uniprot/A0A7I2V442> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP363_r138524/DataNode/df497> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A7I2YQU7> , <http://purl.uniprot.org/uniprot/A0A7I2V4D4> , <http://purl.uniprot.org/uniprot/A0A7I2V3M8> , <http://purl.uniprot.org/uniprot/A0A7I2YQJ1> , <http://purl.uniprot.org/uniprot/A0A024R0L5> , <http://purl.uniprot.org/uniprot/P49840> , <http://purl.uniprot.org/uniprot/A8MT37> , <http://purl.uniprot.org/uniprot/A0A7I2YQM8> , <http://purl.uniprot.org/uniprot/A0A7I2V4Q6> , <http://purl.uniprot.org/uniprot/A0A7I2V5S8> , <http://purl.uniprot.org/uniprot/A0A7I2V2H8> , <http://purl.uniprot.org/uniprot/A0A7I2V5B3> , <http://purl.uniprot.org/uniprot/A0A7I2V5D7> , <http://purl.uniprot.org/uniprot/A0A7I2V553> , <http://purl.uniprot.org/uniprot/A0A7I2V418> , <http://purl.uniprot.org/uniprot/A0A7I2YQV9> , <http://purl.uniprot.org/uniprot/A0A7I2V379> , <http://purl.uniprot.org/uniprot/A0A7I2V2P9> , <http://purl.uniprot.org/uniprot/A0A7I2V341> , <http://purl.uniprot.org/uniprot/A0A7I2YQA9> , <http://purl.uniprot.org/uniprot/A0A7I2V345> , <http://purl.uniprot.org/uniprot/A0A7I2V627> , <http://purl.uniprot.org/uniprot/A0A7I2V442> , <http://purl.uniprot.org/uniprot/A0A7I2V5Q2> , <http://purl.uniprot.org/uniprot/A0A7I2V3H9> , <http://purl.uniprot.org/uniprot/A0A7I2V485> , <http://purl.uniprot.org/uniprot/A0A7I2V3W5> , <http://purl.uniprot.org/uniprot/A0A7I2V4Z1> , <http://purl.uniprot.org/uniprot/A0A7I2YQA1> , <http://purl.uniprot.org/uniprot/A0A7I2V2Q4> , <http://purl.uniprot.org/uniprot/A0A7I2V4Y3> , <http://purl.uniprot.org/uniprot/A0A7I2V2J2> , <http://purl.uniprot.org/uniprot/A0A7I2V2P8> , <http://purl.uniprot.org/uniprot/A0A7I2YQ76> , <http://purl.uniprot.org/uniprot/A0A7I2V511> , <http://purl.uniprot.org/uniprot/A0A7I2V5P6> , <http://purl.uniprot.org/uniprot/A0A7I2V2P0> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/2931> .

<https://identifiers.org/ncbigene/7248>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "TSC1" ;
        dc:identifier       <https://identifiers.org/ncbigene/7248> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "7248" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP363_r138524> , <http://rdf.wikipathways.org/Pathway/WP363_r138524/WP/Interaction/b3fef> , <http://rdf.wikipathways.org/Pathway/WP363_r138524/WP/Interaction/id64d620d6> , <http://rdf.wikipathways.org/Pathway/WP363_r138524/WP/Interaction/ed855> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000165699> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/7248> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/TSC1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A2R8Y6W1> , <https://identifiers.org/uniprot/A0A2R8Y5N2> , <https://identifiers.org/uniprot/Q86WV8> , <https://identifiers.org/uniprot/X5D9D2> , <https://identifiers.org/uniprot/Q59IT9> , <https://identifiers.org/uniprot/A0A2R8YGX7> , <https://identifiers.org/uniprot/A0A2R8YGL0> , <https://identifiers.org/uniprot/A0A2R8Y5Q4> , <https://identifiers.org/uniprot/A0A2R8Y5S3> , <https://identifiers.org/uniprot/A0A2R8Y5U8> , <https://identifiers.org/uniprot/A0A2R8Y6T5> , <https://identifiers.org/uniprot/A0A2R8YD74> , <https://identifiers.org/uniprot/A0A2R8YFV7> , <https://identifiers.org/uniprot/A0A2R8Y5J1> , <https://identifiers.org/uniprot/Q92574> , <https://identifiers.org/uniprot/A0A2R8Y6S1> , <https://identifiers.org/uniprot/A0A2R8Y7E9> , <https://identifiers.org/uniprot/A0A2R8Y756> , <https://identifiers.org/uniprot/A0A2R8YEH9> , <https://identifiers.org/uniprot/A0A2R8Y419> , <https://identifiers.org/uniprot/A0A2R8Y6S8> , <https://identifiers.org/uniprot/A0A2R8Y5M3> , <https://identifiers.org/uniprot/A0A2R8Y6N1> , <https://identifiers.org/uniprot/A0A2R8Y5F8> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP363_r138524/DataNode/dfcbe> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q59IT9> , <http://purl.uniprot.org/uniprot/A0A2R8YD74> , <http://purl.uniprot.org/uniprot/A0A2R8Y5M3> , <http://purl.uniprot.org/uniprot/Q86WV8> , <http://purl.uniprot.org/uniprot/A0A2R8Y5J1> , <http://purl.uniprot.org/uniprot/A0A2R8Y5S3> , <http://purl.uniprot.org/uniprot/A0A2R8YGX7> , <http://purl.uniprot.org/uniprot/A0A2R8Y419> , <http://purl.uniprot.org/uniprot/A0A2R8Y5N2> , <http://purl.uniprot.org/uniprot/A0A2R8Y756> , <http://purl.uniprot.org/uniprot/A0A2R8YGL0> , <http://purl.uniprot.org/uniprot/A0A2R8Y6W1> , <http://purl.uniprot.org/uniprot/Q92574> , <http://purl.uniprot.org/uniprot/A0A2R8Y6S1> , <http://purl.uniprot.org/uniprot/X5D9D2> , <http://purl.uniprot.org/uniprot/A0A2R8Y6N1> , <http://purl.uniprot.org/uniprot/A0A2R8Y7E9> , <http://purl.uniprot.org/uniprot/A0A2R8Y6T5> , <http://purl.uniprot.org/uniprot/A0A2R8Y5Q4> , <http://purl.uniprot.org/uniprot/A0A2R8Y5F8> , <http://purl.uniprot.org/uniprot/A0A2R8YFV7> , <http://purl.uniprot.org/uniprot/A0A2R8Y6S8> , <http://purl.uniprot.org/uniprot/A0A2R8YEH9> , <http://purl.uniprot.org/uniprot/A0A2R8Y5U8> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/7248> .

<http://rdf.wikipathways.org/Pathway/WP363_r138524/WP/Interaction/c568c>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP363_r138524> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP363_r138524/Interaction/c568c> ;
        wp:participants   <https://identifiers.org/ncbigene/55361> , <https://identifiers.org/ncbigene/4920> ;
        wp:source         <https://identifiers.org/ncbigene/4920> ;
        wp:target         <https://identifiers.org/ncbigene/55361> .

<https://identifiers.org/ncbigene/6934>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "TCF7L2" ;
        dc:identifier       <https://identifiers.org/ncbigene/6934> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "6934" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP363_r138524> , <http://rdf.wikipathways.org/Pathway/WP363_r138524/WP/Interaction/a89cf> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000148737> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/6934> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/TCF7L2> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A0A0MTL7> , <https://identifiers.org/uniprot/A0A994J711> , <https://identifiers.org/uniprot/Q5JRY3> , <https://identifiers.org/uniprot/H0YEE5> , <https://identifiers.org/uniprot/A0A1B0GVE1> , <https://identifiers.org/uniprot/C6ZRJ7> , <https://identifiers.org/uniprot/Q5VVR8> , <https://identifiers.org/uniprot/C6ZRK5> , <https://identifiers.org/uniprot/Q6FHW4> , <https://identifiers.org/uniprot/Q5VVR5> , <https://identifiers.org/uniprot/Q5JRY4> , <https://identifiers.org/uniprot/A0A0D9SGH8> , <https://identifiers.org/uniprot/A0A1B0GU84> , <https://identifiers.org/uniprot/Q5VVR7> , <https://identifiers.org/uniprot/A0A994J4F0> , <https://identifiers.org/uniprot/Q9NQB0> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP363_r138524/DataNode/f1d4e> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q9NQB0> , <http://purl.uniprot.org/uniprot/A0A0D9SGH8> , <http://purl.uniprot.org/uniprot/A0A994J711> , <http://purl.uniprot.org/uniprot/Q6FHW4> , <http://purl.uniprot.org/uniprot/H0YEE5> , <http://purl.uniprot.org/uniprot/A0A0A0MTL7> , <http://purl.uniprot.org/uniprot/Q5JRY3> , <http://purl.uniprot.org/uniprot/A0A1B0GU84> , <http://purl.uniprot.org/uniprot/A0A994J4F0> , <http://purl.uniprot.org/uniprot/Q5JRY4> , <http://purl.uniprot.org/uniprot/C6ZRK5> , <http://purl.uniprot.org/uniprot/Q5VVR5> , <http://purl.uniprot.org/uniprot/A0A1B0GVE1> , <http://purl.uniprot.org/uniprot/C6ZRJ7> , <http://purl.uniprot.org/uniprot/Q5VVR8> , <http://purl.uniprot.org/uniprot/Q5VVR7> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/6934> .

<https://identifiers.org/ncbigene/1453>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "CSNK1D" ;
        dc:identifier       <https://identifiers.org/ncbigene/1453> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "1453" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP363_r138524> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000141551> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/1453> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/CSNK1D> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/J3KRS6> , <https://identifiers.org/uniprot/J3QQI9> , <https://identifiers.org/uniprot/J3QQU8> , <https://identifiers.org/uniprot/B4DLF1> , <https://identifiers.org/uniprot/H7BYT1> , <https://identifiers.org/uniprot/H0Y2N6> , <https://identifiers.org/uniprot/J3KRM8> , <https://identifiers.org/uniprot/P48730> , <https://identifiers.org/uniprot/J3QS70> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP363_r138524/DataNode/bc928> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P48730> , <http://purl.uniprot.org/uniprot/H7BYT1> , <http://purl.uniprot.org/uniprot/J3QQI9> , <http://purl.uniprot.org/uniprot/J3QQU8> , <http://purl.uniprot.org/uniprot/J3KRS6> , <http://purl.uniprot.org/uniprot/H0Y2N6> , <http://purl.uniprot.org/uniprot/B4DLF1> , <http://purl.uniprot.org/uniprot/J3QS70> , <http://purl.uniprot.org/uniprot/J3KRM8> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/1453> .

<http://rdf.wikipathways.org/Pathway/WP363_r138524/WP/Interaction/bef9d>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP363_r138524> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP363_r138524/Interaction/bef9d> ;
        wp:participants   <https://identifiers.org/ncbigene/1857> , <https://identifiers.org/ncbigene/5594> ;
        wp:source         <https://identifiers.org/ncbigene/5594> ;
        wp:target         <https://identifiers.org/ncbigene/1857> .

<http://rdf.wikipathways.org/Pathway/WP363_r138524/WP/Interaction/cd68f>
        rdf:type          wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP363_r138524> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP363_r138524/Interaction/cd68f> .

<https://identifiers.org/wikipathways/WP363_r138524>
        rdf:type               wp:Pathway , skos:Collection ;
        dc:identifier          <https://identifiers.org/wikipathways/WP363> ;
        dc:source              "WikiPathways" ;
        dc:title               "Wnt signaling, NetPath"@en ;
        dcterms:description    "WNT signal, through the canonical pathway, controls cell fate determination and through the non-canonical pathway controls cell movement and tissue polarity. The name \"wnt\" is a fusion of two terms, wg derived from the Drosophila gene wingless (wg) and int derived from the proto-oncogene integration-1, which is the mammalian homolog of wg. ÃŸ-catenin is the key regulated effector of Wnt, involved in canonical signaling . Free ÃŸ-catenin is bound by a multiprotein \"destruction complex\". The ÃŸ-catenin destruction complex is comprised of ÃŸ-catenin, scaffold proteins (APC, AXIN) and serine/threonine kinases that phosphorylate ÃŸ-catenin casein kinase 1 (CSNK1A1, CSNK1D, CSNK1E, CSNK1G1) and GSK3B. The sequential phosphorylation of ÃŸ-catenin by casein kinase 1 and GSK3 is recognised by an SCF-class E3-ubiquitin ligase, which targets it for polyubiquitination and proteosomal destruction. Canonical WNT signals are transduced through a two-part receptor, a seven-transmembrane Frizzled (FZD) and low density lipoprotein receptor-related protein 5/6 (LRP5/LRP6) to a ÃŸ-catenin (CTNNB1) signaling cascade. On recruitment of deshevelled (DVL1) to FZD and AXIN to LRP6, ÃŸ-catenin destruction complex disassembles leading to its stabilization and nuclear accumulation. Nuclear ÃŸ-catenin binds to T-cell factor/lymphoid enhancer factor (TCF/LEF) family of transcription factors and Legless family docking protein, BCL9. These activate the transcription of Wnt target genes CCND1, MYC. Non-canonical WNT signaling diverges downstream after being transduced through FZD family receptors and co-receptors, ROR2 and RYK. This pathway does not involve ÃŸ-catenin-mediated gene expression. Small G proteins such as RAC1, RHOA and downstream effectors of RAC including JNK are DVL-dependant effector molecules of the non-canonical pathway. These have been implicated in cytoskeletal rearrangement, dendrite growth and control of cell polarity and orientation. Nemo-like kinase (NLK) and nuclear factor of activated T cells (NFAT) are Ca2+-dependant effectors of the non-canonical pathway. NLK inhibits canonical pathway by phosphorylation of TCF/LEF family transcription factors. NFAT transcription factor is implicated in convergent extension during early embryogenesis and carcinogenic metastasis.\n  \nPlease access this pathway at [NetSlim](http://www.netpath.org/netslim/wnt_pathway.html) database.\n\nIf you use this pathway, please cite the following paper:\nKandasamy, K., Mohan, S. S., Raju, R., Keerthikumar, S., Kumar, G. S. S., Venugopal, A. K., Telikicherla, D., Navarro, J. D., Mathivanan, S., Pecquet, C., Gollapudi, S. K., Tattikota, S. G., Mohan, S., Padhukasahasram, H., Subbannayya, Y., Goel, R., Jacob, H. K. C., Zhong, J., Sekhar, R., Nanjappa, V., Balakrishnan, L., Subbaiah, R., Ramachandra, Y. L., Rahiman, B. A., Prasad, T. S. K., Lin, J., Houtman, J. C. D., Desiderio, S., Renauld, J., Constantinescu, S. N., Ohara, O., Hirano, T., Kubo, M., Singh, S., Khatri, P., Draghici, S., Bader, G. D., Sander, C., Leonard, W. J. and Pandey, A. (2010). NetPath: A public resource of curated signal transduction pathways. <i>Genome Biology</i>. 11:R3.\n\nThis pathway is part the [CPTAC Assay Portal](https://assays.cancer.gov/available_assays?wp_id=WP363)." ;
        dcterms:identifier     "WP363" ;
        dcterms:references     <https://identifiers.org/pubmed/20067622> ;
        cito:cites             <https://identifiers.org/pubmed/20067622> ;
        wp:isAbout             <http://rdf.wikipathways.org/Pathway/WP363_r138524> ;
        wp:ontologyTag         wp:Curation:ONTOX , wp:Curation:AnalysisCollection , obo:PW_0000201 , obo:PW_0000008 ;
        wp:organism            obo:NCBITaxon_9606 ;
        wp:organismName        "Homo sapiens" ;
        wp:pathwayOntologyTag  obo:PW_0000201 , obo:PW_0000008 ;
        foaf:img               <https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=png&pwTitle=Pathway:WP363&oldid=138524> , <https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=svg&pwTitle=Pathway:WP363&oldid=138524> ;
        foaf:page              <http://www.wikipathways.org/instance/WP363_r138524> .

<https://identifiers.org/ncbigene/607>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "BCL9" ;
        dc:identifier       <https://identifiers.org/ncbigene/607> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "607" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP363_r138524> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000116128> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/607> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/BCL9> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/O00512> , <https://identifiers.org/uniprot/A0A804HI55> , <https://identifiers.org/uniprot/A0A024QYY4> , <https://identifiers.org/uniprot/A0A804HIV1> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP363_r138524/DataNode/d329d> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A024QYY4> , <http://purl.uniprot.org/uniprot/A0A804HI55> , <http://purl.uniprot.org/uniprot/O00512> , <http://purl.uniprot.org/uniprot/A0A804HIV1> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/607> .

<https://identifiers.org/ncbigene/8313>
        rdf:type            wp:Rna , wp:DataNode ;
        rdfs:label          "AXIN2" ;
        dc:identifier       <https://identifiers.org/ncbigene/8313> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "8313" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP363_r138524> , <http://rdf.wikipathways.org/Pathway/WP363_r138524/WP/Interaction/id54c4b5ca> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000168646> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/8313> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/AXIN2> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/F5GX43> , <https://identifiers.org/uniprot/J3QQJ3> , <https://identifiers.org/uniprot/Q9Y2T1> , <https://identifiers.org/uniprot/J3QRK4> , <https://identifiers.org/uniprot/E7ES00> , <https://identifiers.org/uniprot/A0A1B0GX50> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP363_r138524/DataNode/ca892> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/J3QQJ3> , <http://purl.uniprot.org/uniprot/E7ES00> , <http://purl.uniprot.org/uniprot/Q9Y2T1> , <http://purl.uniprot.org/uniprot/J3QRK4> , <http://purl.uniprot.org/uniprot/A0A1B0GX50> , <http://purl.uniprot.org/uniprot/F5GX43> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/8313> .

<http://rdf.wikipathways.org/Pathway/WP363_r138524/WP/Interaction/e9469>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP363_r138524> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP363_r138524/Interaction/e9469> ;
        wp:participants   <https://identifiers.org/ncbigene/5599> , <https://identifiers.org/ncbigene/387> ;
        wp:source         <https://identifiers.org/ncbigene/387> ;
        wp:target         <https://identifiers.org/ncbigene/5599> .

<https://identifiers.org/ncbigene/8395>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "PIP5K1B" ;
        dc:identifier       <https://identifiers.org/ncbigene/8395> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "8395" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP363_r138524> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000107242> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/8395> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/PIP5K1B> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A0A0MT25> , <https://identifiers.org/uniprot/O14986> , <https://identifiers.org/uniprot/A0A0A0MRU3> , <https://identifiers.org/uniprot/A0A0A0MSP5> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP363_r138524/DataNode/e7077> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A0A0MT25> , <http://purl.uniprot.org/uniprot/O14986> , <http://purl.uniprot.org/uniprot/A0A0A0MRU3> , <http://purl.uniprot.org/uniprot/A0A0A0MSP5> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/8395> .

<https://identifiers.org/ncbigene/5601>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "MAPK9" ;
        dc:identifier       <https://identifiers.org/ncbigene/5601> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "5601" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP363_r138524> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000050748> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/5601> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/MAPK9> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/P45984> , <https://identifiers.org/uniprot/D7R525> , <https://identifiers.org/uniprot/D7R528> , <https://identifiers.org/uniprot/E5RJ57> , <https://identifiers.org/uniprot/J3KNK1> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP363_r138524/DataNode/fdf8e> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/E5RJ57> , <http://purl.uniprot.org/uniprot/D7R525> , <http://purl.uniprot.org/uniprot/J3KNK1> , <http://purl.uniprot.org/uniprot/P45984> , <http://purl.uniprot.org/uniprot/D7R528> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/5601> .

<http://rdf.wikipathways.org/Pathway/WP363_r138524/WP/Interaction/f19aa>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP363_r138524> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP363_r138524/Interaction/f19aa> ;
        wp:participants   <https://identifiers.org/ncbigene/5879> , <https://identifiers.org/ncbigene/1855> ;
        wp:source         <https://identifiers.org/ncbigene/1855> ;
        wp:target         <https://identifiers.org/ncbigene/5879> .

<http://rdf.wikipathways.org/Pathway/WP363_r138524/WP/Interaction/idde943844>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP363_r138524> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP363_r138524/Interaction/idde943844> ;
        wp:participants   <https://identifiers.org/ncbigene/8312> , <https://identifiers.org/ncbigene/10023> ;
        wp:source         <https://identifiers.org/ncbigene/10023> ;
        wp:target         <https://identifiers.org/ncbigene/8312> .
