@prefix biopax:  <http://www.biopax.org/release/biopax-level3.owl#> .
@prefix cito:    <http://purl.org/spar/cito/> .
@prefix dc:      <http://purl.org/dc/elements/1.1/> .
@prefix dcterms: <http://purl.org/dc/terms/> .
@prefix foaf:    <http://xmlns.com/foaf/0.1/> .
@prefix freq:    <http://purl.org/cld/freq/> .
@prefix gpml:    <http://vocabularies.wikipathways.org/gpml#> .
@prefix obo:     <http://purl.obolibrary.org/obo/> .
@prefix owl:     <http://www.w3.org/2002/07/owl#> .
@prefix pav:     <http://purl.org/pav/> .
@prefix prov:    <http://www.w3.org/ns/prov#> .
@prefix rdf:     <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix rdfs:    <http://www.w3.org/2000/01/rdf-schema#> .
@prefix skos:    <http://www.w3.org/2004/02/skos/core#> .
@prefix void:    <http://rdfs.org/ns/void#> .
@prefix wp:      <http://vocabularies.wikipathways.org/wp#> .
@prefix wprdf:   <http://rdf.wikipathways.org/> .
@prefix xsd:     <http://www.w3.org/2001/XMLSchema#> .

<https://identifiers.org/pubmed/9427750>
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        dc:source           "PubMed" ;
        dcterms:identifier  "9427750" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4016_r141198> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/9427750> .

<https://identifiers.org/pubmed/22991823>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "22991823" ;
        dcterms:isPartOf    <https://identifiers.org/uniprot/P38398> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/22991823> .

<http://rdf.wikipathways.org/Pathway/WP4016_r141198/WP/Interaction/idf094010a>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4016_r141198> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4016_r141198/Interaction/idf094010a> ;
        wp:participants   <https://identifiers.org/reactome/R-HSA-5693571> , <https://identifiers.org/uniprot/P49736> ;
        wp:source         <https://identifiers.org/uniprot/P49736> ;
        wp:target         <https://identifiers.org/reactome/R-HSA-5693571> .

<https://doi.org/10.1074%2FJBC.C300249200>
        dc:source           "DOI" ;
        dcterms:identifier  "10.1074/JBC.C300249200" .

<https://identifiers.org/pubmed/17478428>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "17478428" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4016_r141198/WP/Interaction/idd697a61c> , <http://rdf.wikipathways.org/Pathway/WP4016_r141198/WP/Interaction/id133f9a08> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/17478428> .

<http://rdf.wikipathways.org/Pathway/WP4016_r141198/WP/Interaction/idcb4cc33c>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4016_r141198> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4016_r141198/Interaction/idcb4cc33c> ;
        wp:participants   <https://identifiers.org/wikipathways/WP1775> , <https://identifiers.org/uniprot/O15297> ;
        wp:source         <https://identifiers.org/uniprot/O15297> ;
        wp:target         <https://identifiers.org/wikipathways/WP1775> .

<https://identifiers.org/pubmed/22973052>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "22973052" ;
        dcterms:isPartOf    <https://identifiers.org/uniprot/O94762> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/22973052> .

<https://identifiers.org/pubmed/16818604>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "16818604" ;
        dcterms:isPartOf    <https://identifiers.org/uniprot/Q99708> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/16818604> .

<https://identifiers.org/pubmed/10320477>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "10320477" ;
        dcterms:isPartOf    <https://identifiers.org/uniprot/P14785> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/10320477> .

<https://identifiers.org/pubmed/17588522>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "17588522" ;
        dcterms:isPartOf    <https://identifiers.org/uniprot/P61077> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/17588522> .

<https://identifiers.org/pubmed/18974355>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "18974355" ;
        dcterms:isPartOf    <https://identifiers.org/uniprot/Q9NZC9> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/18974355> .

<http://rdf.wikipathways.org/Pathway/WP4016_r141198/WP/Interaction/id9a05548c>
        rdf:type          wp:Stimulation , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4016_r141198> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4016_r141198/Interaction/id9a05548c> ;
        wp:participants   <https://identifiers.org/uniprot/P51587> , <https://identifiers.org/uniprot/P60896> ;
        wp:source         <https://identifiers.org/uniprot/P60896> ;
        wp:target         <https://identifiers.org/uniprot/P51587> .

<https://identifiers.org/pubmed/21857671>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "21857671" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4016_r141198/WP/Interaction/id157fc7eb> , <https://identifiers.org/uniprot/O76064> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/21857671> .

<https://identifiers.org/pubmed/19525936>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "19525936" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4016_r141198/WP/Interaction/idfb856de4> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/19525936> .

<https://identifiers.org/pubmed/16116421>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "16116421" ;
        dcterms:isPartOf    <https://identifiers.org/uniprot/Q9BX63> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/16116421> .

<http://rdf.wikipathways.org/Pathway/WP4016_r141198/ComplexBinding/ad5ea>
        rdf:type          wp:ComplexBinding , wp:Binding , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4016_r141198> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4016_r141198/Group/ad5ea> ;
        wp:participants   <https://identifiers.org/uniprot/Q92878> , <https://identifiers.org/uniprot/O60934> , <https://identifiers.org/uniprot/P49959> , <http://rdf.wikipathways.org/Pathway/WP4016_r141198/Complex/ad5ea> .

<https://identifiers.org/pubmed/10777662>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "10777662" ;
        dcterms:isPartOf    <https://identifiers.org/uniprot/O60921> , <https://identifiers.org/uniprot/Q99638> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q28142735> ;
        owl:sameAs          <https://doi.org/10.1006%2FGENO.2000.6142> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/10777662> .

<https://identifiers.org/pubmed/15707391>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "15707391" ;
        dcterms:isPartOf    <https://identifiers.org/uniprot/Q9HAW4> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q24529007> ;
        owl:sameAs          <https://doi.org/10.1042%2FBJ20041966> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/15707391> .

<http://rdf.wikipathways.org/Pathway/WP4016_r141198/WP/Interaction/id25e31783>
        rdf:type            wp:DirectedInteraction , wp:Stimulation , wp:Interaction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4016_r141198> ;
        dcterms:references  <https://identifiers.org/pubmed/18769153> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4016_r141198/Interaction/id25e31783> ;
        wp:participants     <https://identifiers.org/uniprot/Q92547> , <https://identifiers.org/uniprot/Q8WXE1> ;
        wp:source           <https://identifiers.org/uniprot/Q8WXE1> ;
        wp:target           <https://identifiers.org/uniprot/Q92547> .

<https://identifiers.org/pubmed/23364835>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "23364835" ;
        dcterms:isPartOf    <https://identifiers.org/uniprot/O75419> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/23364835> .

<https://identifiers.org/pubmed/27342858>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "27342858" ;
        dcterms:isPartOf    <https://identifiers.org/uniprot/P60896> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/27342858> .

<https://identifiers.org/uniprot/P09874>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "PARP1" ;
        dc:identifier       <https://identifiers.org/uniprot/P09874> ;
        dc:source           "UniProtKB" ;
        dcterms:identifier  "P09874" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4016_r141198> , <http://rdf.wikipathways.org/Pathway/WP4016_r141198/WP/Interaction/id8fca04da> ;
        dcterms:references  <https://identifiers.org/pubmed/19344625> , <https://identifiers.org/pubmed/17396150> , <https://identifiers.org/pubmed/19661379> , <https://identifiers.org/pubmed/23230272> , <https://identifiers.org/pubmed/18172500> , <https://identifiers.org/pubmed/27067600> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000143799> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/142> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/PARP1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A7I2V5E9> , <https://identifiers.org/uniprot/A0A7I2V384> , <https://identifiers.org/uniprot/P09874> , <https://identifiers.org/uniprot/A0A024R3T8> , <https://identifiers.org/uniprot/A0A7I2V3E1> , <https://identifiers.org/uniprot/A0A7I2V625> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4016_r141198/DataNode/d317b> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A7I2V3E1> , <http://purl.uniprot.org/uniprot/A0A7I2V384> , <http://purl.uniprot.org/uniprot/A0A7I2V5E9> , <http://purl.uniprot.org/uniprot/P09874> , <http://purl.uniprot.org/uniprot/A0A024R3T8> , <http://purl.uniprot.org/uniprot/A0A7I2V625> ;
        foaf:page           <http://www.uniprot.org/uniprot/P09874> .

<https://identifiers.org/pubmed/15314022>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "15314022" ;
        dcterms:isPartOf    <https://identifiers.org/uniprot/Q9BXW9> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/15314022> .

<https://identifiers.org/uniprot/O94761>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "RECQL4" ;
        dc:identifier       <https://identifiers.org/uniprot/O94761> ;
        dc:source           "UniProtKB" ;
        dcterms:identifier  "O94761" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4016_r141198> ;
        dcterms:references  <https://identifiers.org/pubmed/15317757> , <https://identifiers.org/pubmed/15960976> , <https://identifiers.org/pubmed/16617241> , <https://identifiers.org/pubmed/11032027> , <https://identifiers.org/pubmed/15221963> , <https://identifiers.org/pubmed/10552928> , <https://identifiers.org/pubmed/9878247> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000160957> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/9401> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/RECQL4> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/O94761> , <https://identifiers.org/uniprot/V9GY60> , <https://identifiers.org/uniprot/V9GYA3> , <https://identifiers.org/uniprot/V9GZ64> , <https://identifiers.org/uniprot/V9GYB6> , <https://identifiers.org/uniprot/V9GY28> , <https://identifiers.org/uniprot/A0A087X072> , <https://identifiers.org/uniprot/A0A087WTJ0> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4016_r141198/DataNode/e1cee> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A087X072> , <http://purl.uniprot.org/uniprot/V9GYA3> , <http://purl.uniprot.org/uniprot/V9GZ64> , <http://purl.uniprot.org/uniprot/O94761> , <http://purl.uniprot.org/uniprot/V9GY28> , <http://purl.uniprot.org/uniprot/V9GYB6> , <http://purl.uniprot.org/uniprot/A0A087WTJ0> , <http://purl.uniprot.org/uniprot/V9GY60> ;
        foaf:page           <http://www.uniprot.org/uniprot/O94761> .

<https://doi.org/10.1021%2FTX900449U>
        dc:source           "DOI" ;
        dcterms:identifier  "10.1021/TX900449U" .

<https://identifiers.org/pubmed/21198351>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "21198351" ;
        dcterms:isPartOf    <https://identifiers.org/uniprot/P29590> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/21198351> .

<https://identifiers.org/pubmed/16908529>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "16908529" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4016_r141198/WP/Interaction/id704faa76> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/16908529> .

<https://identifiers.org/uniprot/Q6UWZ7>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "FAM175A" ;
        dc:identifier       <https://identifiers.org/uniprot/Q6UWZ7> ;
        dc:source           "UniProtKB" ;
        dcterms:identifier  "Q6UWZ7" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4016_r141198/WP/Interaction/id29cd99be> , <https://identifiers.org/wikipathways/WP4016_r141198> ;
        dcterms:references  <https://identifiers.org/pubmed/17525340> , <https://identifiers.org/pubmed/19261748> , <https://identifiers.org/pubmed/19261749> , <https://identifiers.org/pubmed/26778126> , <https://identifiers.org/pubmed/22357538> , <https://identifiers.org/pubmed/17643121> , <https://identifiers.org/pubmed/18077395> , <https://identifiers.org/pubmed/17643122> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000163322> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/84142> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/ABRAXAS1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A087WWJ9> , <https://identifiers.org/uniprot/A0A087WZ78> , <https://identifiers.org/uniprot/D6REL5> , <https://identifiers.org/uniprot/D6RAN3> , <https://identifiers.org/uniprot/Q6UWZ7> , <https://identifiers.org/uniprot/E9PHB9> , <https://identifiers.org/uniprot/A0A087WXK1> , <https://identifiers.org/uniprot/D6RHI5> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4016_r141198/DataNode/aa1ad> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A087WZ78> , <http://purl.uniprot.org/uniprot/A0A087WWJ9> , <http://purl.uniprot.org/uniprot/D6RHI5> , <http://purl.uniprot.org/uniprot/Q6UWZ7> , <http://purl.uniprot.org/uniprot/D6RAN3> , <http://purl.uniprot.org/uniprot/E9PHB9> , <http://purl.uniprot.org/uniprot/D6REL5> , <http://purl.uniprot.org/uniprot/A0A087WXK1> ;
        foaf:page           <http://www.uniprot.org/uniprot/Q6UWZ7> .

<https://identifiers.org/pubmed/17525341>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "17525341" ;
        dcterms:isPartOf    <https://identifiers.org/uniprot/Q96RL1> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/17525341> .

<https://identifiers.org/pubmed/9733514>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "9733514" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4016_r141198/WP/Interaction/id963d6c48> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q28609838> ;
        owl:sameAs          <https://doi.org/10.1126%2FSCIENCE.281.5383.1674> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/9733514> .

<https://identifiers.org/uniprot/P43351>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "RAD52" ;
        dc:identifier       <https://identifiers.org/uniprot/P43351> ;
        dc:source           "UniProtKB" ;
        dcterms:identifier  "P43351" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4016_r141198> , <http://rdf.wikipathways.org/Pathway/WP4016_r141198/WP/Interaction/id754d0627> , <http://rdf.wikipathways.org/Pathway/WP4016_r141198/WP/Interaction/a6ce8> , <http://rdf.wikipathways.org/Pathway/WP4016_r141198/WP/Interaction/id345c904d> ;
        dcterms:references  <https://identifiers.org/pubmed/12750383> , <https://identifiers.org/pubmed/12379650> , <https://identifiers.org/pubmed/7526206> , <https://identifiers.org/pubmed/7774019> , <https://identifiers.org/pubmed/19338310> , <https://identifiers.org/pubmed/10673031> , <https://identifiers.org/pubmed/12370410> , <https://identifiers.org/pubmed/17525332> , <https://identifiers.org/pubmed/12883740> , <https://identifiers.org/pubmed/12191481> , <https://identifiers.org/pubmed/21804533> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000002016> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/5893> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/RAD52> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/F5H1K5> , <https://identifiers.org/uniprot/P43351> , <https://identifiers.org/uniprot/E9PF95> , <https://identifiers.org/uniprot/F5GX95> , <https://identifiers.org/uniprot/Q5DR82> , <https://identifiers.org/uniprot/F5GX32> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4016_r141198/DataNode/d8e27> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/E9PF95> , <http://purl.uniprot.org/uniprot/P43351> , <http://purl.uniprot.org/uniprot/F5GX95> , <http://purl.uniprot.org/uniprot/F5H1K5> , <http://purl.uniprot.org/uniprot/F5GX32> , <http://purl.uniprot.org/uniprot/Q5DR82> ;
        foaf:page           <http://www.uniprot.org/uniprot/P43351> .

<https://identifiers.org/pubmed/15314187>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "15314187" ;
        dcterms:isPartOf    <https://identifiers.org/uniprot/O60921> , <https://identifiers.org/uniprot/Q99638> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/15314187> .

<https://identifiers.org/pubmed/10205172>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "10205172" ;
        dcterms:isPartOf    <https://identifiers.org/uniprot/P20439> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/10205172> .

<https://identifiers.org/pubmed/8632903>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
        dcterms:identifier  "8632903" ;
        dcterms:isPartOf    <https://identifiers.org/uniprot/P04637> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/8632903> .

<https://identifiers.org/pubmed/18066086>
        rdf:type            wp:PublicationReference ;
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<http://rdf.wikipathways.org/Pathway/WP4016_r141198/WP/Interaction/a6ce8>
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        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/14636568> .

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<http://rdf.wikipathways.org/Pathway/WP4016_r141198/WP/Interaction/idd362369f>
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<http://rdf.wikipathways.org/Pathway/WP4016_r141198/WP/Interaction/id54ec80c1>
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<https://doi.org/10.1038%2FNATURE01445>
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<https://identifiers.org/uniprot/O96017>
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<https://identifiers.org/uniprot/P24941>
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        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000123374> ;
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        foaf:page           <http://www.uniprot.org/uniprot/P24941> .

<https://identifiers.org/pubmed/8589730>
        rdf:type            wp:PublicationReference ;
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<https://identifiers.org/pubmed/10477523>
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        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/20413593> .

<https://doi.org/10.1128%2FMCB.19.7.4633>
        dc:source           "DOI" ;
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<https://doi.org/10.1016%2FJ.MOLCEL.2011.02.016>
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<https://identifiers.org/pubmed/3025664>
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<http://rdf.wikipathways.org/Pathway/WP4016_r141198/WP/Interaction/id8970121f>
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        wp:participants     <https://identifiers.org/uniprot/P04637> , <https://identifiers.org/uniprot/Q12888> ;
        wp:source           <https://identifiers.org/uniprot/Q12888> ;
        wp:target           <https://identifiers.org/uniprot/P04637> .

<https://identifiers.org/kegg.pathway/hsa04110>
        rdf:type            wp:DataNode , wp:Pathway ;
        rdfs:label          "M-phase progression" ;
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<https://identifiers.org/pubmed/16478997>
        rdf:type            wp:PublicationReference ;
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        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/16478997> .

<http://rdf.wikipathways.org/Pathway/WP4016_r141198/WP/Interaction/id87f53ac8>
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        wp:participants     <https://identifiers.org/uniprot/Q14676> , <https://identifiers.org/uniprot/O76064> ;
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        wp:target           <https://identifiers.org/uniprot/O76064> .

<https://identifiers.org/pubmed/12228710>
        rdf:type            wp:PublicationReference ;
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        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/12228710> .

<https://identifiers.org/pubmed/22154951>
        rdf:type            wp:PublicationReference ;
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        dcterms:isPartOf    <https://identifiers.org/uniprot/Q8NEM0> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/22154951> .

<https://identifiers.org/pubmed/11369231>
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        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/11369231> .

<https://identifiers.org/uniprot/O94782>
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<https://doi.org/10.1038%2FNSMB.1504>
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<http://rdf.wikipathways.org/Pathway/WP4016_r141198/WP/Interaction/id748bbb63>
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<http://rdf.wikipathways.org/Pathway/WP4016_r141198/WP/Interaction/idcf334a2d>
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        dcterms:isPartOf    <https://identifiers.org/uniprot/O14757> ;
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<https://doi.org/10.1038%2FNCB1384>
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        wp:target         <https://identifiers.org/uniprot/Q12888> .

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        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/18775730> .

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        wp:target         <https://identifiers.org/uniprot/P51587> .

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        foaf:page           <http://www.uniprot.org/uniprot/P43246> .

<https://identifiers.org/pubmed/12379650>
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<https://doi.org/10.1073%2FPNAS.1217781110>
        dc:source           "DOI" ;
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<https://identifiers.org/pubmed/7700386>
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        dcterms:isPartOf    <https://identifiers.org/uniprot/Q99638> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/12734188> .

<http://rdf.wikipathways.org/Pathway/WP4016_r141198/WP/Interaction/iddaaa215d>
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        wp:source           <https://identifiers.org/uniprot/Q13535> ;
        wp:target           <https://identifiers.org/uniprot/Q9UPV0> .

<http://rdf.wikipathways.org/Pathway/WP4016_r141198/WP/Interaction/id29cd99be>
        rdf:type          wp:Binding , wp:DirectedInteraction , wp:Interaction ;
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<https://identifiers.org/pubmed/12354784>
        rdf:type            wp:PublicationReference ;
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        dcterms:isPartOf    <https://identifiers.org/uniprot/O15360> ;
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<https://identifiers.org/pubmed/18769153>
        rdf:type            wp:PublicationReference ;
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        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/18769153> .

<https://identifiers.org/pubmed/10373512>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
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<https://identifiers.org/pubmed/25609649>
        rdf:type            wp:PublicationReference ;
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        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/25609649> .

<https://identifiers.org/pubmed/22083606>
        rdf:type            wp:PublicationReference ;
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<https://identifiers.org/pubmed/17081985>
        rdf:type            wp:PublicationReference ;
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        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/17081985> .

<https://identifiers.org/uniprot/Q13263>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "TRIM28" ;
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        dc:source           "UniProtKB" ;
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        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000130726> ;
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        foaf:page           <http://www.uniprot.org/uniprot/Q9NUW8> .

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        wp:source         <https://identifiers.org/uniprot/P53350> ;
        wp:target         <https://identifiers.org/reactome/R-HSA-69481> .

<https://doi.org/10.1074%2FJBC.275.14.10498>
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        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/SMARCC2> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/F8VZW6> , <https://identifiers.org/uniprot/Q8TAQ2> , <https://identifiers.org/uniprot/F8VXC8> , <https://identifiers.org/uniprot/A0A024RB22> ;
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<https://identifiers.org/pubmed/15870257>
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<https://identifiers.org/pubmed/14695475>
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<https://identifiers.org/pubmed/1393148>
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        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/1393148> .

<http://rdf.wikipathways.org/Pathway/WP4016_r141198/WP/Interaction/id963d6c48>
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        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4016_r141198/Interaction/id963d6c48> ;
        wp:participants     <https://identifiers.org/uniprot/P04637> , <https://identifiers.org/uniprot/Q13535> ;
        wp:source           <https://identifiers.org/uniprot/Q13535> ;
        wp:target           <https://identifiers.org/uniprot/P04637> .

<http://rdf.wikipathways.org/Pathway/WP4016_r141198/WP/Interaction/id8311001e>
        rdf:type            wp:Interaction , wp:DirectedInteraction , wp:Stimulation ;
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        wp:source           <https://identifiers.org/uniprot/Q99708> ;
        wp:target           <https://identifiers.org/uniprot/Q13535> .

<http://rdf.wikipathways.org/Pathway/WP4016_r141198/Complex/a10b6>
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<https://identifiers.org/uniprot/O75943>
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        foaf:page           <http://www.uniprot.org/uniprot/O75943> .

<https://identifiers.org/pubmed/16899510>
        rdf:type            wp:PublicationReference ;
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<http://rdf.wikipathways.org/Pathway/WP4016_r141198/WP/Interaction/id345c904d>
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        wp:participants     <https://identifiers.org/uniprot/P43351> , <https://identifiers.org/uniprot/Q06609> ;
        wp:source           <https://identifiers.org/uniprot/P43351> ;
        wp:target           <https://identifiers.org/uniprot/Q06609> .

<https://identifiers.org/pubmed/22237204>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
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        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/22237204> .

<http://rdf.wikipathways.org/Pathway/WP4016_r141198/WP/Interaction/id157fc7eb>
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        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4016_r141198/Interaction/id157fc7eb> ;
        wp:participants     <https://identifiers.org/wikipathways/WP707> , <https://identifiers.org/uniprot/O76064> ;
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<https://identifiers.org/pubmed/20231364>
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<https://identifiers.org/pubmed/24485656>
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<http://rdf.wikipathways.org/Pathway/WP4016_r141198/WP/Interaction/id85362427>
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<https://identifiers.org/pubmed/16547522>
        rdf:type            wp:PublicationReference ;
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<https://identifiers.org/pubmed/19707781>
        rdf:type            wp:PublicationReference ;
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<https://identifiers.org/pubmed/15317757>
        rdf:type            wp:PublicationReference ;
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        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/15317757> .

<https://doi.org/10.1126%2FSCIENCE.297.5588.1837>
        dc:source           "DOI" ;
        dcterms:identifier  "10.1126/SCIENCE.297.5588.1837" .

<https://identifiers.org/uniprot/P49959>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "MRE11A" ;
        dc:identifier       <https://identifiers.org/uniprot/P49959> ;
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        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000020922> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/4361> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/MRE11> ;
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<https://identifiers.org/pubmed/16787914>
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        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/16531125> .

<https://identifiers.org/pubmed/3142690>
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        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/3142690> .

<http://rdf.wikipathways.org/Pathway/WP4016_r141198/WP/Interaction/id941e21ee>
        rdf:type            wp:Interaction , wp:Stimulation , wp:DirectedInteraction ;
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        wp:participants     <https://identifiers.org/uniprot/P04637> , <https://identifiers.org/ensembl/ENSG00000149311> ;
        wp:source           <https://identifiers.org/ensembl/ENSG00000149311> ;
        wp:target           <https://identifiers.org/uniprot/P04637> .

<https://doi.org/10.1073%2FPNAS.2336100100>
        dc:source           "DOI" ;
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<https://identifiers.org/pubmed/20020535>
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<https://identifiers.org/pubmed/7774019>
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<http://rdf.wikipathways.org/Pathway/WP4016_r141198/WP/Interaction/idd81d8c7d>
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        wp:source         <https://identifiers.org/uniprot/P30307> ;
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<https://identifiers.org/pubmed/16633336>
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        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/16633336> .

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        rdf:type            wp:PublicationReference ;
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<https://identifiers.org/uniprot/Q14683>
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<https://doi.org/10.1074%2FJBC.M202172200>
        dc:source           "DOI" ;
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<https://identifiers.org/pubmed/26253028>
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        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/26253028> .

<https://doi.org/10.1038%2F1400>
        dc:source           "DOI" ;
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<http://rdf.wikipathways.org/Pathway/WP4016_r141198/WP/Interaction/idd9bc65e7>
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        wp:source           <https://identifiers.org/ensembl/ENSG00000149311> ;
        wp:target           <https://identifiers.org/uniprot/Q01094> .

<https://identifiers.org/pubmed/17097061>
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        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/17097061> .

<https://identifiers.org/pubmed/9452416>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
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        owl:sameAs          <https://doi.org/10.1074%2FJBC.273.6.3117> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/9452416> .

<http://rdf.wikipathways.org/Pathway/WP4016_r141198/WP/Interaction/ida3df97df>
        rdf:type            wp:Interaction , wp:Inhibition , wp:DirectedInteraction ;
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        wp:participants     <https://identifiers.org/uniprot/Q9HAW4> , <https://identifiers.org/uniprot/Q13535> ;
        wp:source           <https://identifiers.org/uniprot/Q13535> ;
        wp:target           <https://identifiers.org/uniprot/Q9HAW4> .

<https://identifiers.org/pubmed/8969240>
        rdf:type            wp:PublicationReference ;
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        dcterms:isPartOf    <https://identifiers.org/ensembl/ENSG00000149311> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/8969240> .

<https://identifiers.org/pubmed/21501958>
        rdf:type            wp:PublicationReference ;
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        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/21501958> .

<https://identifiers.org/pubmed/15199523>
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        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/15199523> .

<https://identifiers.org/uniprot/P60896>
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        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000127922> ;
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<https://doi.org/10.1126%2FSCIENCE.1140321>
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<http://rdf.wikipathways.org/Pathway/WP4016_r141198/WP/Interaction/idd697a61c>
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<https://doi.org/10.1038%2F3882>
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        dc:title               "DNA IR-damage and cellular response via ATR"@en ;
        dcterms:description    "In fission yeast, the rad3 gene product plays a critical role in sensing DNA structure defects and activating damage response pathways. A structural homologue of rad3 in humans has been identified based on sequence similarity in the protein kinase domain.  ATR (for Ataxia Telangiectasia and Rad3-related) is considered the mammalian counterpart of yeast rad3, Mec1p, and fruit fly Mei-41, proteins involved in DNA damage responses.\nThe ATR protein is a member of the phosphoinositide 3-kinase related kinase family and plays an important role in UV-induced DNA damage checkpoint response and its role as a signal transducer in cell cycle checkpoint has been well established.  Even though it is currently unclear whether ATR functions as a damage sensor, recent evidence shows that ATR may function as an initial sensor in the DNA damage checkpoint response.  Moreover, it has been found that ATR is a DNA-binding protein with higher affinity to UV-damaged than undamaged DNA.  In addition, damaged DNA stimulates the kinase activity of ATR to a significantly higher level than undamaged DNA.\nATR is structurally related to ATM (for Ataxia Telangiectasia Mutated) as well as the yeast PIK family members Mec1p and Rad3.  Mec1p and Rad3 participate in checkpoint pathways induced by DNA replication blocks, DNA strand breaks, and other chromosomal abnormalities, which implies that ATR performs similar functions in mammalian cells.  Reports have demonstrated that overexpression of a catalytically inactive version of ATR (ATRki) in human fibroblasts caused hypersensitivity to gamma-radiation and hydroxyurea and abrogation of the radiation-induced G2 checkpoint.  The checkpoint defects observed in ATR-overexpressing cells resemble those found in AT cells.\nAdditionally, ATR functions as an upstream regulator of p53 phosphorylation in DNA-damaged cells.  ATR phosphorylates p53 at both Ser-15 and Ser-37 in vitro, suggesting that ATR is directly involved in the modification of p53 in DNA-damaged cells.  Recent reports concerning ATM, suggest that ATR and ATM play both overlapping and independent roles in the phosphorylation of p53 during cellular exposure to genotoxic stress.\nAtr is localized to the nuclei of primary spermatocytes, cells that are undergoing meiosis I.  It has been demonstrated that both Atr and Atm proteins have associated protein kinase activity, consistent with their primary structures.  Additionally, Atr and Atm show specific association with chromosomes in cells that are in early meiosis I as demonstrated by antibody localization on surface-spread spermatocytes.  Both the Atr and Atm proteins are present at pairing forks in meiotic prophase as chromosomes synapse; however, they do not colocalize, instead they occupy complementary positions: Atr localizes along unsynapsed chromosome axes and Atm interacts with synapsed axes.\nMeanwhile ATM is activated by damage-induced rapid intermolecular autophosphorylation prior relocalization to sites of DNA breaks, ATR activation seems to require single-stranded DNA (ssDNA) coated with replication protein A.  The recruitment of ATR to damage sites appears to be mediated by an ATR-interacting protein that forms a stable complex with the vast majority of ATR in human cells." ;
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        foaf:page           <http://www.uniprot.org/uniprot/Q99638> .

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        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/11687627> .

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<https://doi.org/10.1074%2FJBC.M303885200>
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<https://identifiers.org/pubmed/12824158>
        rdf:type            wp:PublicationReference ;
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        dcterms:isPartOf    <https://identifiers.org/uniprot/Q12888> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/12824158> .

<http://rdf.wikipathways.org/Pathway/WP4016_r141198/WP/Interaction/iddd798a82>
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        wp:participants     <https://identifiers.org/uniprot/Q13535> , <https://identifiers.org/uniprot/Q6PJP8> ;
        wp:source           <https://identifiers.org/uniprot/Q13535> ;
        wp:target           <https://identifiers.org/uniprot/Q6PJP8> .

<http://rdf.wikipathways.org/Pathway/WP4016_r141198/WP/Interaction/id522046a>
        rdf:type            wp:DirectedInteraction , wp:Stimulation , wp:Interaction ;
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        wp:source           <https://identifiers.org/uniprot/Q14676> ;
        wp:target           <https://identifiers.org/uniprot/Q12888> .

<https://identifiers.org/pubmed/17767920>
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<https://doi.org/10.1038%2F374566A0>
        dc:source           "DOI" ;
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<https://identifiers.org/pubmed/15064416>
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<https://identifiers.org/uniprot/P12004>
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        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000132646> ;
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        owl:sameAs          <http://purl.uniprot.org/uniprot/P12004> ;
        foaf:page           <http://www.uniprot.org/uniprot/P12004> .

<https://identifiers.org/pubmed/11202906>
        rdf:type            wp:PublicationReference ;
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<https://identifiers.org/pubmed/16479174>
        rdf:type            wp:PublicationReference ;
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        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/16479174> .

<https://identifiers.org/pubmed/7915517>
        rdf:type            wp:PublicationReference ;
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        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/7915517> .

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        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/17828269> .

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        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/11371615> .

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        rdf:type            wp:PublicationReference ;
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        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/10480872> .

<https://identifiers.org/pubmed/15299030>
        rdf:type            wp:PublicationReference ;
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        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/15299030> .

<https://identifiers.org/pubmed/9836640>
        rdf:type            wp:PublicationReference ;
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        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/9836640> .

<http://rdf.wikipathways.org/Pathway/WP4016_r141198/WP/Interaction/id4b3f5f25>
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        wp:participants     <https://identifiers.org/uniprot/Q9BXW9> , <https://identifiers.org/uniprot/O94782> ;
        wp:source           <https://identifiers.org/uniprot/O94782> ;
        wp:target           <https://identifiers.org/uniprot/Q9BXW9> .

<https://identifiers.org/uniprot/Q9HAW4>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "CLSPN" ;
        dc:identifier       <https://identifiers.org/uniprot/Q9HAW4> ;
        dc:source           "UniProtKB" ;
        dcterms:identifier  "Q9HAW4" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4016_r141198/WP/Interaction/ida3df97df> , <https://identifiers.org/wikipathways/WP4016_r141198> , <http://rdf.wikipathways.org/Pathway/WP4016_r141198/WP/Interaction/id74312c83> ;
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        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000092853> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/63967> ;
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        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4016_r141198/DataNode/cef24> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/E7ESG2> , <http://purl.uniprot.org/uniprot/Q9HAW4> ;
        foaf:page           <http://www.uniprot.org/uniprot/Q9HAW4> .

<https://identifiers.org/pubmed/11551919>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
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        dcterms:isPartOf    <https://identifiers.org/uniprot/Q99638> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/11551919> .

<https://identifiers.org/pubmed/23680151>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
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        dcterms:isPartOf    <https://identifiers.org/uniprot/P38398> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/23680151> .

<https://identifiers.org/pubmed/20858735>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
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        dcterms:isPartOf    <https://identifiers.org/uniprot/Q13263> ;
        wp:bdbWikidata      <http://www.wikidata.org/entity/Q24300478> ;
        owl:sameAs          <https://doi.org/10.1158%2F1541-7786.MCR-10-0042> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/20858735> .

<https://doi.org/10.1073%2FPNAS.93.24.13890>
        dc:source           "DOI" ;
        dcterms:identifier  "10.1073/PNAS.93.24.13890" .

<https://identifiers.org/pubmed/19097996>
        rdf:type            wp:PublicationReference ;
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        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/19097996> .

<https://doi.org/10.1038%2FNATURE07185>
        dc:source           "DOI" ;
        dcterms:identifier  "10.1038/NATURE07185" .

<https://identifiers.org/uniprot/Q9BXW9>
        rdf:type            wp:Protein , wp:DataNode ;
        rdfs:label          "FANCD2" ;
        dc:identifier       <https://identifiers.org/uniprot/Q9BXW9> ;
        dc:source           "UniProtKB" ;
        dcterms:identifier  "Q9BXW9" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4016_r141198> , <http://rdf.wikipathways.org/Pathway/WP4016_r141198/Complex/b8e7c> , <http://rdf.wikipathways.org/Pathway/WP4016_r141198/WP/Interaction/id777454ee> , <http://rdf.wikipathways.org/Pathway/WP4016_r141198/WP/Interaction/id9067b56e> , <http://rdf.wikipathways.org/Pathway/WP4016_r141198/WP/Interaction/id4b3f5f25> ;
        dcterms:references  <https://identifiers.org/pubmed/15115758> , <https://identifiers.org/pubmed/12239151> , <https://identifiers.org/pubmed/15377654> , <https://identifiers.org/pubmed/11239454> , <https://identifiers.org/pubmed/12086603> , <https://identifiers.org/pubmed/14517836> , <https://identifiers.org/pubmed/15314022> , <https://identifiers.org/pubmed/15671039> , <https://identifiers.org/pubmed/11239453> , <https://identifiers.org/pubmed/15454491> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000144554> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/2177> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/FANCD2> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/H7BZJ7> , <https://identifiers.org/uniprot/F8WE37> , <https://identifiers.org/uniprot/A0A6Q8PFY3> , <https://identifiers.org/uniprot/Q9BXW9> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4016_r141198/DataNode/e5167> , <http://rdf.wikipathways.org/Pathway/WP4016_r141198/DataNode/ab4b4> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/H7BZJ7> , <http://purl.uniprot.org/uniprot/A0A6Q8PFY3> , <http://purl.uniprot.org/uniprot/Q9BXW9> , <http://purl.uniprot.org/uniprot/F8WE37> ;
        foaf:page           <http://www.uniprot.org/uniprot/Q9BXW9> .

<https://identifiers.org/pubmed/9766667>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
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        dcterms:isPartOf    <https://identifiers.org/uniprot/P78527> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/9766667> .

<http://rdf.wikipathways.org/Pathway/WP4016_r141198/ComplexBinding/e48c5>
        rdf:type          wp:ComplexBinding , wp:Binding , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4016_r141198> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4016_r141198/Group/e48c5> ;
        wp:participants   <https://identifiers.org/uniprot/Q96RL1> , <https://identifiers.org/uniprot/P38398> , <https://identifiers.org/uniprot/Q99728> , <http://rdf.wikipathways.org/Pathway/WP4016_r141198/Complex/e48c5> .

<https://identifiers.org/pubmed/16712457>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
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        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP4016_r141198/Complex/f1d17> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/16712457> .

<http://rdf.wikipathways.org/Pathway/WP4016_r141198/WP/Interaction/id9067b56e>
        rdf:type            wp:DirectedInteraction , wp:Stimulation , wp:Interaction ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP4016_r141198> ;
        dcterms:references  <https://identifiers.org/pubmed/16943440> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4016_r141198/Interaction/id9067b56e> ;
        wp:participants     <https://identifiers.org/uniprot/Q9BXW9> , <https://identifiers.org/uniprot/Q13535> ;
        wp:source           <https://identifiers.org/uniprot/Q13535> ;
        wp:target           <https://identifiers.org/uniprot/Q9BXW9> .

<https://identifiers.org/uniprot/O15360>
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        foaf:page           <http://www.uniprot.org/uniprot/O95714> .

<https://identifiers.org/uniprot/P39748>
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        rdfs:label          "FEN1" ;
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        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000168496> ;
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        foaf:page           <http://www.uniprot.org/uniprot/P39748> .

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        rdf:type            wp:PublicationReference ;
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        dcterms:isPartOf    <https://identifiers.org/uniprot/P23025> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/10563794> .

<https://identifiers.org/pubmed/23802008>
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        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/23802008> .

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        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/1332913> .

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        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/24100029> .

<https://identifiers.org/pubmed/7838523>
        rdf:type            wp:PublicationReference ;
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        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/7838523> .

<https://identifiers.org/pubmed/10884395>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
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        dcterms:isPartOf    <https://identifiers.org/uniprot/Q99638> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/10884395> .

<http://rdf.wikipathways.org/Pathway/WP4016_r141198/Complex/c7a50>
        rdf:type          wp:Complex , wp:DataNode ;
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        wp:participants   <https://identifiers.org/uniprot/Q9H9A7> , <https://identifiers.org/uniprot/Q13472> .

<https://identifiers.org/pubmed/23230272>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
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        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/23230272> .

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        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/15356634> .

<https://doi.org/10.1101%2FGAD.207043.112>
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<https://identifiers.org/pubmed/20639885>
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        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/20639885> .

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<https://identifiers.org/pubmed/9822679>
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        rdf:type            wp:PublicationReference ;
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        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/12419808> .

<http://rdf.wikipathways.org/Pathway/WP4016_r141198/WP/Interaction/e487a>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
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        wp:participants   <https://identifiers.org/wikipathways/WP1775> , <https://identifiers.org/uniprot/O15360> ;
        wp:source         <https://identifiers.org/uniprot/O15360> ;
        wp:target         <https://identifiers.org/wikipathways/WP1775> .

<https://identifiers.org/pubmed/11863428>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed" ;
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        dcterms:isPartOf    <https://identifiers.org/uniprot/Q14191> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/11863428> .

<https://identifiers.org/pubmed/18212045>
        rdf:type            wp:PublicationReference ;
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        dcterms:isPartOf    <https://identifiers.org/uniprot/P41182> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/18212045> .

<https://identifiers.org/pubmed/16622405>
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        dcterms:isPartOf    <https://identifiers.org/uniprot/Q14191> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/16622405> .

<https://doi.org/10.1016%2FS1097-2765%2800%2980316-0>
        dc:source           "DOI" ;
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        rdf:type            wp:PublicationReference ;
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        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/11063725> .

<https://identifiers.org/pubmed/17124492>
        rdf:type            wp:PublicationReference ;
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        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/17124492> .

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        rdf:type            wp:PublicationReference ;
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        dcterms:isPartOf    <https://identifiers.org/uniprot/P46063> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/12419324> .

<https://identifiers.org/uniprot/O43324>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "EEF1E1" ;
        dc:identifier       <https://identifiers.org/uniprot/O43324> ;
        dc:source           "UniProtKB" ;
        dcterms:identifier  "O43324" ;
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        dcterms:references  <https://identifiers.org/pubmed/25465621> , <https://identifiers.org/pubmed/19024604> , <https://identifiers.org/pubmed/15680327> , <https://identifiers.org/pubmed/18343821> , <https://identifiers.org/pubmed/22867704> , <https://identifiers.org/pubmed/25609649> , <https://identifiers.org/pubmed/21789020> , <https://identifiers.org/pubmed/24104880> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000124802> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/9521> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/EEF1E1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/H0YAL7> , <https://identifiers.org/uniprot/D6RCQ0> , <https://identifiers.org/uniprot/O43324> , <https://identifiers.org/uniprot/D6RBD7> , <https://identifiers.org/uniprot/H0YAH9> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4016_r141198/DataNode/e7b45> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/D6RCQ0> , <http://purl.uniprot.org/uniprot/H0YAL7> , <http://purl.uniprot.org/uniprot/O43324> , <http://purl.uniprot.org/uniprot/H0YAH9> , <http://purl.uniprot.org/uniprot/D6RBD7> ;
        foaf:page           <http://www.uniprot.org/uniprot/O43324> .

<http://rdf.wikipathways.org/Pathway/WP4016_r141198/Complex/ad5ea>
        rdf:type          wp:Complex , wp:DataNode ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4016_r141198> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP4016_r141198/Group/ad5ea> ;
        wp:participants   <https://identifiers.org/uniprot/Q92878> , <https://identifiers.org/uniprot/O60934> , <https://identifiers.org/uniprot/P49959> .

<http://rdf.wikipathways.org/Pathway/WP4016_r141198/WP/Interaction/idb361a58a>
        rdf:type          wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP4016_r141198> ;
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        wp:participants   <https://identifiers.org/uniprot/Q9BX63> , <https://identifiers.org/uniprot/P27694> ;
        wp:source         <https://identifiers.org/uniprot/P27694> ;
        wp:target         <https://identifiers.org/uniprot/Q9BX63> .

<https://identifiers.org/uniprot/P04637>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "TP53" ;
        dc:identifier       <https://identifiers.org/uniprot/P04637> ;
        dc:source           "UniProtKB" ;
        dcterms:identifier  "P04637" ;
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        dcterms:references  <https://identifiers.org/pubmed/3025664> , <https://identifiers.org/pubmed/4006916> , <https://identifiers.org/pubmed/2946935> , <https://identifiers.org/pubmed/8632903> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000141510> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/7157> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/TP53> ;
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<https://doi.org/10.1006%2FGENO.2000.6142>
        dc:source           "DOI" ;
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<https://doi.org/10.1074%2FJBC.M111854200>
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<https://identifiers.org/pubmed/17115032>
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<http://rdf.wikipathways.org/Pathway/WP4016_r141198/WP/Interaction/id89c4204c>
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        wp:source         <https://identifiers.org/uniprot/Q9UPV0> ;
        wp:target         <https://identifiers.org/reactome/R-HSA-69481> .

<https://identifiers.org/wikipathways/WP1775>
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<http://rdf.wikipathways.org/Pathway/WP4016_r141198/ComplexBinding/c7a50>
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        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/9572863> .

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        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/14734534> .

<https://identifiers.org/uniprot/P08047>
        rdf:type            wp:DataNode , wp:Protein ;
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        dc:source           "UniProtKB" ;
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<https://doi.org/10.1016%2FJ.CCR.2005.08.004>
        dc:source           "DOI" ;
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<https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=svg&pwTitle=Pathway:WP4016&oldid=141198>
        rdf:type        foaf:Image ;
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        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/14976165> .

<http://rdf.wikipathways.org/Pathway/WP4016_r141198/WP/Interaction/id754d0627>
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        wp:source         <https://identifiers.org/uniprot/P43351> ;
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<https://identifiers.org/pubmed/16153896>
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        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/16153896> .

<https://identifiers.org/uniprot/O76064>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "RNF8" ;
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        dc:source           "UniProtKB" ;
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        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000112130> ;
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        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/RNF8> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/F8WDH8> , <https://identifiers.org/uniprot/O76064> , <https://identifiers.org/uniprot/F8WEW6> , <https://identifiers.org/uniprot/H7C4L7> , <https://identifiers.org/uniprot/C9J858> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4016_r141198/DataNode/ba8e9> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/F8WDH8> , <http://purl.uniprot.org/uniprot/H7C4L7> , <http://purl.uniprot.org/uniprot/F8WEW6> , <http://purl.uniprot.org/uniprot/C9J858> , <http://purl.uniprot.org/uniprot/O76064> ;
        foaf:page           <http://www.uniprot.org/uniprot/O76064> .

<https://identifiers.org/pubmed/19440044>
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        dc:source           "PubMed" ;
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        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/21242293> .

<https://identifiers.org/uniprot/Q99728>
        rdf:type            wp:DataNode , wp:Protein ;
        rdfs:label          "BARD1" ;
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        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSG00000138376> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/580> ;
        wp:bdbHgncSymbol    <https://identifiers.org/hgnc.symbol/BARD1> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A087X0C6> , <https://identifiers.org/uniprot/F8WCG2> , <https://identifiers.org/uniprot/A0A087WZ19> , <https://identifiers.org/uniprot/C9J6M1> , <https://identifiers.org/uniprot/C9IYG1> , <https://identifiers.org/uniprot/A0A494C142> , <https://identifiers.org/uniprot/F6MDI1> , <https://identifiers.org/uniprot/A0A087X2H0> , <https://identifiers.org/uniprot/Q99728> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP4016_r141198/DataNode/d6a86> , <http://rdf.wikipathways.org/Pathway/WP4016_r141198/DataNode/c75b0> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A087X2H0> , <http://purl.uniprot.org/uniprot/C9J6M1> , <http://purl.uniprot.org/uniprot/A0A087X0C6> , <http://purl.uniprot.org/uniprot/A0A494C142> , <http://purl.uniprot.org/uniprot/Q99728> , <http://purl.uniprot.org/uniprot/C9IYG1> , <http://purl.uniprot.org/uniprot/A0A087WZ19> , <http://purl.uniprot.org/uniprot/F6MDI1> , <http://purl.uniprot.org/uniprot/F8WCG2> ;
        foaf:page           <http://www.uniprot.org/uniprot/Q99728> .
