@prefix biopax:  <http://www.biopax.org/release/biopax-level3.owl#> .
@prefix cito:    <http://purl.org/spar/cito/> .
@prefix dc:      <http://purl.org/dc/elements/1.1/> .
@prefix dcterms: <http://purl.org/dc/terms/> .
@prefix foaf:    <http://xmlns.com/foaf/0.1/> .
@prefix freq:    <http://purl.org/cld/freq/> .
@prefix gpml:    <http://vocabularies.wikipathways.org/gpml#> .
@prefix obo:     <http://purl.obolibrary.org/obo/> .
@prefix owl:     <http://www.w3.org/2002/07/owl#> .
@prefix pav:     <http://purl.org/pav/> .
@prefix prov:    <http://www.w3.org/ns/prov#> .
@prefix rdf:     <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix rdfs:    <http://www.w3.org/2000/01/rdf-schema#> .
@prefix skos:    <http://www.w3.org/2004/02/skos/core#> .
@prefix void:    <http://rdfs.org/ns/void#> .
@prefix wp:      <http://vocabularies.wikipathways.org/wp#> .
@prefix wprdf:   <http://rdf.wikipathways.org/> .
@prefix xsd:     <http://www.w3.org/2001/XMLSchema#> .

<https://identifiers.org/ncbigene/534923>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "AKT2" ;
        dc:identifier       <https://identifiers.org/ncbigene/534923> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "534923" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2892_r117537> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSBTAG00000001400> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/534923> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A3Q1MQ45> , <https://identifiers.org/uniprot/E1B9D1> , <https://identifiers.org/uniprot/A0A3Q1NH21> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2892_r117537/DataNode/cd3ab> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A3Q1MQ45> , <http://purl.uniprot.org/uniprot/A0A3Q1NH21> , <http://purl.uniprot.org/uniprot/E1B9D1> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/534923> .

<https://identifiers.org/ensembl/ENSBTAG00000009907>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "MAPK4" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSBTAG00000009907> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSBTAG00000009907" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2892_r117537> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSBTAG00000009907> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/529183> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/F1MVV5> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2892_r117537/DataNode/e12ac> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/F1MVV5> ;
        foaf:page           <https://www.ensembl.org/id/ENSBTAG00000009907> .

<https://identifiers.org/ncbigene/100137872>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "AKT3" ;
        dc:identifier       <https://identifiers.org/ncbigene/100137872> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "100137872" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2892_r117537> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSBTAG00000017788> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/100137872> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/F1MYJ4> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2892_r117537/DataNode/fc371> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/F1MYJ4> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/100137872> .

<https://identifiers.org/ncbigene/540421>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "ARAF" ;
        dc:identifier       <https://identifiers.org/ncbigene/540421> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "540421" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2892_r117537> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSBTAG00000005039> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/540421> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A452DI16> , <https://identifiers.org/uniprot/Q2KJA0> , <https://identifiers.org/uniprot/A0A3Q1MIQ9> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2892_r117537/DataNode/dc1d6> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A3Q1MIQ9> , <http://purl.uniprot.org/uniprot/Q2KJA0> , <http://purl.uniprot.org/uniprot/A0A452DI16> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/540421> .

<https://identifiers.org/pmc/PMC7019052>
        rdf:type            wp:PublicationReference ;
        dc:source           "PubMed Central" ;
        dcterms:identifier  "PMC7019052" ;
        cito:cites          <https://identifiers.org/wikipathways/WP2892> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/PMC7019052> .

<https://identifiers.org/ensembl/ENSBTAG00000012019>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "IRS2" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSBTAG00000012019> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSBTAG00000012019" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2892_r117537/Complex/ba839> , <https://identifiers.org/wikipathways/WP2892_r117537> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSBTAG00000012019> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/F1MJE0> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2892_r117537/DataNode/b8897> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/F1MJE0> ;
        foaf:page           <https://www.ensembl.org/id/ENSBTAG00000012019> .

<https://identifiers.org/ncbigene/506322>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "NRAS" ;
        dc:identifier       <https://identifiers.org/ncbigene/506322> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "506322" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2892_r117537> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSBTAG00000046797> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/506322> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A5D7R9> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2892_r117537/DataNode/db9fe> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A5D7R9> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/506322> .

<https://identifiers.org/ncbigene/534492>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "MAPK14" ;
        dc:identifier       <https://identifiers.org/ncbigene/534492> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "534492" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2892_r117537> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSBTAG00000020783> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/534492> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A3Q1M517> , <https://identifiers.org/uniprot/A0A3Q1LTT9> , <https://identifiers.org/uniprot/F6PU21> , <https://identifiers.org/uniprot/A0A3Q1M8H8> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2892_r117537/DataNode/f0b72> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A3Q1M517> , <http://purl.uniprot.org/uniprot/A0A3Q1LTT9> , <http://purl.uniprot.org/uniprot/F6PU21> , <http://purl.uniprot.org/uniprot/A0A3Q1M8H8> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/534492> .

<https://identifiers.org/ensembl/ENSBTAG00000016072>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "SHC2" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSBTAG00000016072> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSBTAG00000016072" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2892_r117537> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSBTAG00000016072> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/533455> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/F1N5N3> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2892_r117537/DataNode/f1b6f> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/F1N5N3> ;
        foaf:page           <https://www.ensembl.org/id/ENSBTAG00000016072> .

<https://identifiers.org/ensembl/ENSBTAG00000021761>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "BRAF" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSBTAG00000021761> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSBTAG00000021761" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2892_r117537> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSBTAG00000021761> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/536051> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A3Q1LML5> , <https://identifiers.org/uniprot/F1MDL4> , <https://identifiers.org/uniprot/A0A3Q1M353> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2892_r117537/DataNode/aeacd> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A3Q1LML5> , <http://purl.uniprot.org/uniprot/A0A3Q1M353> , <http://purl.uniprot.org/uniprot/F1MDL4> ;
        foaf:page           <https://www.ensembl.org/id/ENSBTAG00000021761> .

<https://identifiers.org/ncbigene/618906>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "MAPK11" ;
        dc:identifier       <https://identifiers.org/ncbigene/618906> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "618906" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2892_r117537> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSBTAG00000030182> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/618906> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/G3X793> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2892_r117537/DataNode/ce9b3> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/G3X793> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/618906> .

<https://identifiers.org/ncbigene/512125>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "MAPK15" ;
        dc:identifier       <https://identifiers.org/ncbigene/512125> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "512125" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2892_r117537> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSBTAG00000019864> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/512125> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A3Q1M825> , <https://identifiers.org/uniprot/A0A3Q1LU59> , <https://identifiers.org/uniprot/F1N3N6> , <https://identifiers.org/uniprot/A0A3Q1M9F7> , <https://identifiers.org/uniprot/A0A3Q1LXN5> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2892_r117537/DataNode/da698> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A3Q1LU59> , <http://purl.uniprot.org/uniprot/A0A3Q1M825> , <http://purl.uniprot.org/uniprot/A0A3Q1M9F7> , <http://purl.uniprot.org/uniprot/F1N3N6> , <http://purl.uniprot.org/uniprot/A0A3Q1LXN5> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/512125> .

<https://identifiers.org/ensembl/ENSBTAG00000007876>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "MAPK8" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSBTAG00000007876> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSBTAG00000007876" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2892_r117537> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSBTAG00000007876> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/539941> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A3Q1NK45> , <https://identifiers.org/uniprot/A0A3Q1MG18> , <https://identifiers.org/uniprot/A0A3Q1LWJ8> , <https://identifiers.org/uniprot/F1MM73> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2892_r117537/DataNode/f0ee5> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A3Q1NK45> , <http://purl.uniprot.org/uniprot/F1MM73> , <http://purl.uniprot.org/uniprot/A0A3Q1LWJ8> , <http://purl.uniprot.org/uniprot/A0A3Q1MG18> ;
        foaf:page           <https://www.ensembl.org/id/ENSBTAG00000007876> .

<https://identifiers.org/ncbigene/507196>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "SHC1" ;
        dc:identifier       <https://identifiers.org/ncbigene/507196> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "507196" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2892_r117537> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSBTAG00000019838> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/507196> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/Q0IIE2> , <https://identifiers.org/uniprot/E1B716> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2892_r117537/DataNode/e08ac> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q0IIE2> , <http://purl.uniprot.org/uniprot/E1B716> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/507196> .

<https://identifiers.org/wikipathways/WP2892>
        pav:hasVersion  <https://identifiers.org/wikipathways/WP2892_r117537> .

<https://identifiers.org/ncbigene/541140>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "KRAS" ;
        dc:identifier       <https://identifiers.org/ncbigene/541140> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "541140" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2892_r117537> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSBTAG00000009778> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/541140> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A3Q1LMP2> , <https://identifiers.org/uniprot/E1BMX0> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2892_r117537/DataNode/a1318> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/E1BMX0> , <http://purl.uniprot.org/uniprot/A0A3Q1LMP2> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/541140> .

<https://identifiers.org/ncbigene/281848>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "IGF1R" ;
        dc:identifier       <https://identifiers.org/ncbigene/281848> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "281848" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2892_r117537/WP/Interaction/ide91f707b> , <https://identifiers.org/wikipathways/WP2892_r117537> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSBTAG00000021527> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/281848> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/G1K218> , <https://identifiers.org/uniprot/A0A3Q1NB49> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2892_r117537/DataNode/d6a84> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/G1K218> , <http://purl.uniprot.org/uniprot/A0A3Q1NB49> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/281848> .

<http://rdf.wikipathways.org/Pathway/WP2892_r117537/ComplexBinding/ba839>
        rdf:type          wp:ComplexBinding , wp:Binding , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2892_r117537> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2892_r117537/Group/ba839> ;
        wp:participants   <https://identifiers.org/ensembl/ENSBTAG00000021308> , <https://identifiers.org/ensembl/ENSBTAG00000012019> , <http://rdf.wikipathways.org/Pathway/WP2892_r117537/Complex/ba839> .

obo:NCBITaxon_9913  obo:NCIT_C179773  "9913" .

<https://identifiers.org/ncbigene/535327>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "MAPK13" ;
        dc:identifier       <https://identifiers.org/ncbigene/535327> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "535327" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2892_r117537> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSBTAG00000010007> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/535327> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A3Q1MGB3> , <https://identifiers.org/uniprot/A0A3Q1M757> , <https://identifiers.org/uniprot/Q5E9Q6> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2892_r117537/DataNode/b493b> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q5E9Q6> , <http://purl.uniprot.org/uniprot/A0A3Q1M757> , <http://purl.uniprot.org/uniprot/A0A3Q1MGB3> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/535327> .

<https://identifiers.org/ncbigene/512943>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "MAPK12" ;
        dc:identifier       <https://identifiers.org/ncbigene/512943> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "512943" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2892_r117537> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSBTAG00000019574> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/512943> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A3Q1LKQ5> , <https://identifiers.org/uniprot/A5PJL3> , <https://identifiers.org/uniprot/A0A3Q1LJZ7> , <https://identifiers.org/uniprot/A0A3Q1MF91> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2892_r117537/DataNode/ac188> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A3Q1LJZ7> , <http://purl.uniprot.org/uniprot/A5PJL3> , <http://purl.uniprot.org/uniprot/A0A3Q1LKQ5> , <http://purl.uniprot.org/uniprot/A0A3Q1MF91> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/512943> .

<https://identifiers.org/ensembl/ENSBTAG00000010312>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "MAPK1" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSBTAG00000010312> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSBTAG00000010312" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2892_r117537> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSBTAG00000010312> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/327672> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/P46196> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2892_r117537/DataNode/e682e> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/P46196> ;
        foaf:page           <https://www.ensembl.org/id/ENSBTAG00000010312> .

<https://identifiers.org/ncbigene/100139219>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "MTOR" ;
        dc:identifier       <https://identifiers.org/ncbigene/100139219> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "100139219" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2892_r117537> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSBTAG00000015325> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/100139219> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A3Q1M2S6> , <https://identifiers.org/uniprot/A0A3Q1MIZ9> , <https://identifiers.org/uniprot/A0A3Q1MN73> , <https://identifiers.org/uniprot/E1BFB4> , <https://identifiers.org/uniprot/A0A3Q1MZG6> , <https://identifiers.org/uniprot/A0A3Q1MEZ6> , <https://identifiers.org/uniprot/A0A3Q1LUE8> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2892_r117537/DataNode/a8674> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A3Q1MZG6> , <http://purl.uniprot.org/uniprot/E1BFB4> , <http://purl.uniprot.org/uniprot/A0A3Q1MIZ9> , <http://purl.uniprot.org/uniprot/A0A3Q1MEZ6> , <http://purl.uniprot.org/uniprot/A0A3Q1LUE8> , <http://purl.uniprot.org/uniprot/A0A3Q1M2S6> , <http://purl.uniprot.org/uniprot/A0A3Q1MN73> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/100139219> .

<https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=svg&pwTitle=Pathway:WP2892&oldid=117537>
        rdf:type        foaf:Image ;
        dcterms:format  "image/svg+xml" .

<https://identifiers.org/pubmed/22554198>
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        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2892_r117537> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/22554198> .

<https://identifiers.org/ncbigene/524734>
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        dc:source           "Entrez Gene" ;
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        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSBTAG00000022583> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/524734> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/G3N270> , <https://identifiers.org/uniprot/E1BCR0> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2892_r117537/DataNode/e2148> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/E1BCR0> , <http://purl.uniprot.org/uniprot/G3N270> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/524734> .

<https://identifiers.org/ncbigene/100298939>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "HRAS" ;
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        dc:source           "Entrez Gene" ;
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        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2892_r117537> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSBTAG00000046644> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/100298939> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/G3N1U2> , <https://identifiers.org/uniprot/G3MXH2> , <https://identifiers.org/uniprot/A0A3Q1LKB7> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2892_r117537/DataNode/ecb89> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/G3MXH2> , <http://purl.uniprot.org/uniprot/G3N1U2> , <http://purl.uniprot.org/uniprot/A0A3Q1LKB7> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/100298939> .

<http://rdf.wikipathways.org/Pathway/WP2892_r117537/Complex/ba839>
        rdf:type          wp:Complex , wp:DataNode ;
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        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2892_r117537/Group/ba839> ;
        wp:participants   <https://identifiers.org/ensembl/ENSBTAG00000021308> , <https://identifiers.org/ensembl/ENSBTAG00000012019> .

<https://identifiers.org/wikipathways/WP2892_r117537>
        rdf:type               wp:Pathway , skos:Collection ;
        dc:identifier          <https://identifiers.org/wikipathways/WP2892> ;
        dc:source              "WikiPathways" ;
        dc:title               "IGF-1 signaling"@en ;
        dcterms:description    "The activated IGF-1R (Insulin-like growth factor 1 receptor) regulates cellular adhesion, cytoskeletal organization and migration through interaction with adhesion molecules and integrin. In normal physiology the IGF-1R stimulates linear body growth, promotes neuronal survival and myelination, postnatal mammary gland development and lactation and is implicated in bone formation and renal function (Fortes et al,2013)." ;
        dcterms:identifier     "WP2892" ;
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        cito:cites             <https://identifiers.org/pubmed/22554198> , <https://identifiers.org/pubmed/7758431> ;
        wp:isAbout             <http://rdf.wikipathways.org/Pathway/WP2892_r117537> ;
        wp:ontologyTag         obo:PW_0000003 , wp:Curation:AnalysisCollection ;
        wp:organism            obo:NCBITaxon_9913 ;
        wp:organismName        "Bos taurus" ;
        wp:pathwayOntologyTag  obo:PW_0000003 ;
        foaf:img               <https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=svg&pwTitle=Pathway:WP2892&oldid=117537> , <https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=png&pwTitle=Pathway:WP2892&oldid=117537> ;
        foaf:page              <http://www.wikipathways.org/instance/WP2892_r117537> .

<https://identifiers.org/pubmed/7758431>
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        dc:source           "PubMed" ;
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        foaf:page           <http://www.ncbi.nlm.nih.gov/pubmed/7758431> .

<https://identifiers.org/ncbigene/615013>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "BAD" ;
        dc:identifier       <https://identifiers.org/ncbigene/615013> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "615013" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2892_r117537> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSBTAG00000012511> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/615013> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/F1MUT9> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2892_r117537/DataNode/d7dd0> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/F1MUT9> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/615013> .

<https://identifiers.org/ncbigene/512696>
        rdf:type            wp:GeneProduct , wp:DataNode ;
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        dc:source           "Entrez Gene" ;
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        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2892_r117537> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSBTAG00000011375> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/512696> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/F1MP52> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2892_r117537/DataNode/adc06> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/F1MP52> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/512696> .

<https://identifiers.org/ncbigene/531391>
        rdf:type            wp:DataNode , wp:GeneProduct ;
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        dc:identifier       <https://identifiers.org/ncbigene/531391> ;
        dc:source           "Entrez Gene" ;
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        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2892_r117537> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSBTAG00000016156> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/531391> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A3Q1MNN7> , <https://identifiers.org/uniprot/E1B8P9> , <https://identifiers.org/uniprot/A0A3Q1M7B5> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2892_r117537/DataNode/bc53f> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/E1B8P9> , <http://purl.uniprot.org/uniprot/A0A3Q1MNN7> , <http://purl.uniprot.org/uniprot/A0A3Q1M7B5> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/531391> .

<https://identifiers.org/ncbigene/538094>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "MAPK6" ;
        dc:identifier       <https://identifiers.org/ncbigene/538094> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "538094" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2892_r117537> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSBTAG00000005865> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/538094> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/G5E577> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2892_r117537/DataNode/e718c> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/G5E577> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/538094> .

<https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=png&pwTitle=Pathway:WP2892&oldid=117537>
        rdf:type        foaf:Image ;
        dcterms:format  "image/png" .

<https://identifiers.org/ensembl/ENSBTAG00000021308>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "IRS1" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSBTAG00000021308> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSBTAG00000021308" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2892_r117537> , <http://rdf.wikipathways.org/Pathway/WP2892_r117537/Complex/ba839> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSBTAG00000021308> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/F1MYE0> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2892_r117537/DataNode/d36d6> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/F1MYE0> ;
        foaf:page           <https://www.ensembl.org/id/ENSBTAG00000021308> .

<https://identifiers.org/ncbigene/521196>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "RAF1" ;
        dc:identifier       <https://identifiers.org/ncbigene/521196> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "521196" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2892_r117537> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSBTAG00000045748> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/521196> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A7E3S4> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2892_r117537/DataNode/ac0b0> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A7E3S4> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/521196> .

<https://identifiers.org/ncbigene/281239>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "IGF1" ;
        dc:identifier       <https://identifiers.org/ncbigene/281239> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "281239" ;
        dcterms:isPartOf    <http://rdf.wikipathways.org/Pathway/WP2892_r117537/WP/Interaction/ide91f707b> , <https://identifiers.org/wikipathways/WP2892_r117537> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSBTAG00000011082> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/281239> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/P07455> , <https://identifiers.org/uniprot/F2X2F3> , <https://identifiers.org/uniprot/F2X2F0> , <https://identifiers.org/uniprot/F2X2F1> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2892_r117537/DataNode/e7a24> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/F2X2F0> , <http://purl.uniprot.org/uniprot/F2X2F1> , <http://purl.uniprot.org/uniprot/P07455> , <http://purl.uniprot.org/uniprot/F2X2F3> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/281239> .

<http://rdf.wikipathways.org/Pathway/WP2892_r117537/WP/Interaction/ide91f707b>
        rdf:type          wp:Binding , wp:DirectedInteraction , wp:Interaction ;
        dcterms:isPartOf  <https://identifiers.org/wikipathways/WP2892_r117537> ;
        wp:isAbout        <http://rdf.wikipathways.org/Pathway/WP2892_r117537/Interaction/ide91f707b> ;
        wp:participants   <https://identifiers.org/ncbigene/281848> , <https://identifiers.org/ncbigene/281239> ;
        wp:source         <https://identifiers.org/ncbigene/281239> ;
        wp:target         <https://identifiers.org/ncbigene/281848> .

<https://identifiers.org/ncbigene/537703>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "MAPK7" ;
        dc:identifier       <https://identifiers.org/ncbigene/537703> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "537703" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2892_r117537> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSBTAG00000001014> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/537703> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A5PKJ4> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2892_r117537/DataNode/e3e8f> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A5PKJ4> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/537703> .

<https://identifiers.org/ncbigene/537631>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "MAPK10" ;
        dc:identifier       <https://identifiers.org/ncbigene/537631> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "537631" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2892_r117537> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSBTAG00000020048> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/537631> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A4FV00> , <https://identifiers.org/uniprot/A0A3Q1LRM6> , <https://identifiers.org/uniprot/A0A3Q1LXD7> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2892_r117537/DataNode/c08e4> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A4FV00> , <http://purl.uniprot.org/uniprot/A0A3Q1LRM6> , <http://purl.uniprot.org/uniprot/A0A3Q1LXD7> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/537631> .

<https://identifiers.org/ncbigene/534125>
        rdf:type            wp:DataNode , wp:GeneProduct ;
        rdfs:label          "MAPK9" ;
        dc:identifier       <https://identifiers.org/ncbigene/534125> ;
        dc:source           "Entrez Gene" ;
        dcterms:identifier  "534125" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2892_r117537> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSBTAG00000004709> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/534125> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A3Q1LJU7> , <https://identifiers.org/uniprot/Q2KI72> , <https://identifiers.org/uniprot/A0A3Q1LVH0> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2892_r117537/DataNode/c2379> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/Q2KI72> , <http://purl.uniprot.org/uniprot/A0A3Q1LVH0> , <http://purl.uniprot.org/uniprot/A0A3Q1LJU7> ;
        foaf:page           <http://www.ncbi.nlm.nih.gov/gene/534125> .

<https://identifiers.org/ensembl/ENSBTAG00000017636>
        rdf:type            wp:GeneProduct , wp:DataNode ;
        rdfs:label          "AKT1" ;
        dc:identifier       <https://identifiers.org/ensembl/ENSBTAG00000017636> ;
        dc:source           "Ensembl" ;
        dcterms:identifier  "ENSBTAG00000017636" ;
        dcterms:isPartOf    <https://identifiers.org/wikipathways/WP2892_r117537> ;
        wp:bdbEnsembl       <https://identifiers.org/ensembl/ENSBTAG00000017636> ;
        wp:bdbEntrezGene    <https://identifiers.org/ncbigene/280991> ;
        wp:bdbUniprot       <https://identifiers.org/uniprot/A0A3Q1MJ77> , <https://identifiers.org/uniprot/G3X7B5> ;
        wp:isAbout          <http://rdf.wikipathways.org/Pathway/WP2892_r117537/DataNode/ab1af> ;
        owl:sameAs          <http://purl.uniprot.org/uniprot/A0A3Q1MJ77> , <http://purl.uniprot.org/uniprot/G3X7B5> ;
        foaf:page           <https://www.ensembl.org/id/ENSBTAG00000017636> .
