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<Pathway xmlns="http://pathvisio.org/GPML/2013a" Name="GPCRs, small ligand" Data-Source="WikiPathways" Version="WP353_r138011" Author="[Nsalomonis, MaintBot, Khanspers, Ddigles, Mkutmon, Eweitz, Egonw]" Last-Modified="20250311115049" Organism="Mus musculus">
  <Comment Source="WikiPathways-description">G protein–coupled receptors (GPCRs) which are also known as seven-(pass)-transmembrane domain receptors, 7TM receptors, heptahelical receptors, serpentine receptor, and G protein–linked receptors (GPLR), constitute a large protein family of receptors that detect molecules outside the cell and activate internal signal transduction pathways and, ultimately, cellular responses. Coupling with G proteins, they are called seven-transmembrane receptors because they pass through the cell membrane seven times. Source: [Wikipedia](https://en.wikipedia.org/wiki/G_protein–coupled_receptor)

These small ligand receptors are part of the Rhodopsin-like family of GPCRs. Source: [Wikipedia](https://en.wikipedia.org/wiki/Rhodopsin-like_receptors)</Comment>
  <Comment Source="HomologyConvert">This pathway was inferred from Homo sapiens pathway [http://www.wikipathways.org/index.php?title=Pathway:WP247&amp;amp;amp;amp;oldid=21199 WP247(r21199)] with a 94% conversion rate.</Comment>
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