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<Pathway xmlns="http://pathvisio.org/GPML/2013a" Name="Eicosanoid metabolism via cytochrome P450 monooxygenases" Data-Source="WikiPathways" Version="WP4349_r138032" Author="[Eoinfahy, Ryanmiller, DeSl, Egonw, Eweitz, Khanspers]" Last-Modified="20250312204210" Organism="Mus musculus">
  <Comment Source="WikiPathways-description">This pathway is inspired by the [LIPID MAPS Eicosanoids Pathway expended pathway display](https://lipidmaps.org/pathway/pathways_maps) and extended with the bottom left side of Figure 1 from [Dennis and Norris 2015](https://www.ncbi.nlm.nih.gov/pubmed/26139350).
Eicosanoids are a large group of compounds metabolised from arachidonic acid (AA), either via cyclooxygenases (COX) [WP4347](https://www.wikipathways.org/index.php/Pathway:WP4347), lipooxygenases(LOX) [WP4348](https://www.wikipathways.org/index.php/Pathway:WP4348), or cytochrome P450 monooxygenases (CYP) [WP4349](https://www.wikipathways.org/index.php/Pathway:WP4349).
This pathway visualises the third route, via CYP.

Orange boxes represent peroxisome-proliferator activating receptors (PPARs) potentially activated by the eicosanoids.</Comment>
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