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<Pathway xmlns="http://pathvisio.org/GPML/2013a" Name="mRNA processing" Data-Source="WikiPathways" Version="WP310_r137423" Author="[Nsalomonis, MaintBot, AlexanderPico, Thomas, Khanspers, Ddigles, Cizar, Fehrhart, Egonw]" Last-Modified="20250302080443" Organism="Mus musculus">
  <Comment Source="WikiPathways-description">Adapted from Reactome, see: [REACT 1675.1](http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_1675.1)

This process describes the conversion of precursor messenger RNA into mature messenger RNA (mRNA). The pre-mRNA molecule undergoes three main modifications. These modifications are 5' capping, 3' polyadenylation, and RNA splicing, which occur in the cell nucleus before the RNA is translated.

5' Capping: Capping of the pre-mRNA involves the addition of 7-methylguanosine (m7G) to the 5' end. The cap protects the 5' end of the primary RNA transcript from attack by ribonucleases that have specificity to the 3'5' phosphodiester bonds.

3' Processing: The pre-mRNA processing at the 3' end of the RNA molecule involves cleavage of its 3' end and then the addition of about 200 adenine residues to form a poly(A) tail. As the poly(A) tails is synthesised, it binds multiple copies of poly(A) binding protein, which protects the 3'end from ribonuclease digestion.

Splicing: RNA splicing is the process by which introns, regions of RNA that do not code for protein, are removed from the pre-mRNA and the remaining exons connected to re-form a single continuous molecule.

Description adapted from Wikipedia: http://en.wikipedia.org/wiki/Post-transcriptional_modification</Comment>
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    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
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  <DataNode TextLabel="Ssa2" GraphId="a17" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Ssa2 | Sjogren syndrome antigen A2" />
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  <DataNode TextLabel="Sf3b3" GraphId="a1b" Type="GeneProduct">
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  <DataNode TextLabel="2210008M09Rik" GraphId="a1c" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
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  <DataNode TextLabel="Hnrpa1" GraphId="a1d" Type="GeneProduct">
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  <DataNode TextLabel="Cpeb4" GraphId="a1f" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Cpeb4 | cytoplasmic polyadenylation element bin..." />
    <Graphics CenterX="810.0" CenterY="1206.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="67579" />
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  <DataNode TextLabel="0610009D07Rik" GraphId="a20" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
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    <Graphics CenterX="70.0" CenterY="1150.0" Width="100.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
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  <DataNode TextLabel="Xrn2" GraphId="a23" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Xrn2 | 5â-3â exoribonuclease 2" />
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    <Xref Database="Entrez Gene" ID="24128" />
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  <DataNode TextLabel="Htf9c" GraphId="a2a" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Htf9c | HpaII tiny fragments locus 9c" />
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    <Xref Database="Entrez Gene" ID="15547" />
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  <DataNode TextLabel="Son" GraphId="a30" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Son | Son cell proliferation protein" />
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    <Xref Database="Entrez Gene" ID="20658" />
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  <DataNode TextLabel="Zfp385" GraphId="a33" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Zfp385 | zinc finger protein 385" />
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    <Xref Database="Entrez Gene" ID="29813" />
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  <DataNode TextLabel="Sfrs14" GraphId="a34" Type="GeneProduct">
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    <Xref Database="Entrez Gene" ID="234373" />
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  <DataNode TextLabel="Ddx4" GraphId="a36" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Ddx4 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 4..." />
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    <Xref Database="Entrez Gene" ID="13206" />
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  <DataNode TextLabel="Zmat2" GraphId="a37" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Zmat2 | zinc finger matrin type 2" />
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    <Xref Database="Entrez Gene" ID="66492" />
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  <DataNode TextLabel="Adar" GraphId="a38" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Adar | adenosine deaminase RNA-specific" />
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    <Xref Database="Entrez Gene" ID="56417" />
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  <DataNode TextLabel="Sfrs10" GraphId="a3c" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Sfrs10 | splicing factor arginine/serine-rich..." />
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    <Xref Database="Entrez Gene" ID="20462" />
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  <DataNode TextLabel="1110017C15Rik" GraphId="a3e" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="1110017C15Rik | RIKEN cDNA 1110017C15 gene" />
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    <Xref Database="Entrez Gene" ID="66164" />
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  <DataNode TextLabel="Rpp14" GraphId="a44" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Rpp14 | ribonuclease P 14 subunit (human)" />
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    <Xref Database="Entrez Gene" ID="67053" />
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  <DataNode TextLabel="Rnasel" GraphId="a47" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Rnasel | ribonuclease L (2â 5â-oligoisoadenyl..." />
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    <Xref Database="Entrez Gene" ID="24014" />
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  <DataNode TextLabel="Txnl4" GraphId="a4b" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Txnl4 | thioredoxin-like 4" />
    <Graphics CenterX="796.6666666666666" CenterY="643.3333333333334" Width="73.33333333333333" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="27366" />
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  <DataNode TextLabel="Exosc4" GraphId="a4c" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Exosc4 | exosome component 4" />
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    <Xref Database="Entrez Gene" ID="109075" />
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  <DataNode TextLabel="2400002F11Rik" GraphId="a4d" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="2400002F11Rik | RIKEN cDNA 2400002F11 gene" />
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    <Xref Database="Entrez Gene" ID="66405" />
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  <DataNode TextLabel="6330548G22Rik" GraphId="a4f" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="6330548G22Rik | RIKEN cDNA 6330548G22 gene" />
    <Graphics CenterX="370.0" CenterY="1630.0" Width="100.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="76167" />
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  <DataNode TextLabel="2610024A01Rik" GraphId="a53" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="2610024A01Rik | RIKEN cDNA 2610024A01 gene" />
    <Graphics CenterX="216.66666666666666" CenterY="1370.0" Width="106.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
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  <DataNode TextLabel="Tenr" GraphId="a54" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Tenr | testis nuclear RNA binding protein" />
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  <DataNode TextLabel="Rnu1a2" GraphId="a58" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="U1a2 snRNA" />
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    <Xref Database="Entrez Gene" ID="111972" />
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  <DataNode TextLabel="Cpeb1" GraphId="a5a" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Cpeb1 | cytoplasmic polyadenylation element bin..." />
    <Graphics CenterX="810.0" CenterY="1166.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="12877" />
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  <DataNode TextLabel="Rngtt" GraphId="a5f" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Rngtt | RNA guanylyltransferase and 5â-phosphat..." />
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  <DataNode TextLabel="Secisbp2" GraphId="a63" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Secisbp2 | SECIS binding protein 2" />
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    <Xref Database="Entrez Gene" ID="75420" />
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  <DataNode TextLabel="Rnu2" GraphId="a66" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">GenBank sequence: K00027</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Rnu2 | U2 small nuclear RNA" />
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  <DataNode TextLabel="Rpl26" GraphId="a68" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Rpl26 | ribosomal protein L26" />
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  <DataNode TextLabel="MGI:1351465" GraphId="a6b" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="MGI:1351465 | Ras-GTPase-activating protein SH3..." />
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  <DataNode TextLabel="Cpsf5" GraphId="a77" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Cpsf5 | cleavage and polyadenylation specific f..." />
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  <DataNode TextLabel="AI256354" GraphId="a78" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="AI256354 | expressed sequence AI256354" />
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    <Xref Database="Entrez Gene" ID="103653" />
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  <DataNode TextLabel="Rbm4" GraphId="a7a" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Rbm4 | RNA binding motif protein 4" />
    <Graphics CenterX="953.3333333333334" CenterY="1626.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="19653" />
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  <DataNode TextLabel="Afg3l2" GraphId="a7c" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Afg3l2 | AFG3(ATPase family gene 3)-like 2 (yea..." />
    <Graphics CenterX="70.0" CenterY="1710.0" Width="100.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="69597" />
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  <DataNode TextLabel="Rnps1" GraphId="a7d" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">PMID: 14729963</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Rnps1 | ribonucleic acid binding protein S1" />
    <Graphics CenterX="1816.6666666666667" CenterY="893.3333333333334" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="19826" />
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  <DataNode TextLabel="1700095D18Rik" GraphId="a81" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="RIKEN cDNA 1700095D18 gene" />
    <Graphics CenterX="70.0" CenterY="1530.0" Width="100.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="MGI" ID="MGI:1920805" />
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  <DataNode TextLabel="Hnrpr" GraphId="a82" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Hnrpr" />
    <Graphics CenterX="423.3333333333333" CenterY="433.3333333333333" Width="66.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="74326" />
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  <DataNode TextLabel="Hnrpdl" GraphId="a85" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Hnrpdl | heterogeneous nuclear ribonucleoprotei..." />
    <Graphics CenterX="810.0" CenterY="1666.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="50926" />
  </DataNode>
  <DataNode TextLabel="1190002L16Rik" GraphId="a87" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="1190002L16Rik | RIKEN cDNA 1190002L16 gene" />
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    <Xref Database="Entrez Gene" ID="102462" />
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  <DataNode TextLabel="Exosc9" GraphId="a88" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Exosc9 | exosome component 9" />
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    <Xref Database="Entrez Gene" ID="50911" />
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  <DataNode TextLabel="Park7" GraphId="a8a" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Park7 | Parkinson disease (autosomal recessive..." />
    <Graphics CenterX="1773.3333333333333" CenterY="1486.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="57320" />
  </DataNode>
  <DataNode TextLabel="Rbm17" GraphId="a8b" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Rbm17 | RNA binding motif protein 17" />
    <Graphics CenterX="2000.0" CenterY="843.3333333333334" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="76938" />
  </DataNode>
  <DataNode TextLabel="1700012H05Rik" GraphId="a94" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="1700012H05Rik | RIKEN cDNA 1700012H05 gene" />
    <Graphics CenterX="70.0" CenterY="1470.0" Width="100.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="76572" />
  </DataNode>
  <DataNode TextLabel="Nono" GraphId="a9a" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Nono | non-POU-domain-containing octamer bind..." />
    <Graphics CenterX="2000.0" CenterY="743.3333333333334" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="53610" />
  </DataNode>
  <DataNode TextLabel="Rpl38" GraphId="a9e" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Rpl38 | ribosomal protein L38" />
    <Graphics CenterX="1483.3333333333333" CenterY="1166.6666666666667" Width="106.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="67671" />
  </DataNode>
  <DataNode TextLabel="AI255215" GraphId="aa1" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="expressed sequence AI255215" />
    <Graphics CenterX="516.6666666666666" CenterY="1350.0" Width="63.333333333333336" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="MGI" ID="MGI:2138868" />
  </DataNode>
  <DataNode TextLabel="1200009B18Rik" GraphId="aa4" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="1200009B18Rik | RIKEN cDNA 1200009B18 gene" />
    <Graphics CenterX="70.0" CenterY="1330.0" Width="100.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="67456" />
  </DataNode>
  <DataNode TextLabel="Rpl7" GraphId="aa7" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Rpl7 | ribosomal protein L7" />
    <Graphics CenterX="1906.6666666666667" CenterY="1243.3333333333333" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="19989" />
  </DataNode>
  <DataNode TextLabel="MGI:1336880" GraphId="aa9" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="MGI:1336880 | U5 small nuclear ribonucleoprotei..." />
    <Graphics CenterX="906.6666666666666" CenterY="623.3333333333334" Width="73.33333333333333" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="20624" />
  </DataNode>
  <DataNode TextLabel="4921506I22Rik" GraphId="aad" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="4921506I22Rik | RIKEN cDNA 4921506I22 gene" />
    <Graphics CenterX="370.0" CenterY="1210.0" Width="106.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="66704" />
  </DataNode>
  <DataNode TextLabel="4932422E22Rik" GraphId="ab0" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="4932422E22Rik | RIKEN cDNA 4932422E22 gene" />
    <Graphics CenterX="370.0" CenterY="1410.0" Width="100.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="319695" />
  </DataNode>
  <DataNode TextLabel="Snrpd1" GraphId="ab2" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Snrpd1 | small nuclear ribonucleoprotein D1" />
    <Graphics CenterX="576.6666666666666" CenterY="286.6666666666667" Width="73.33333333333333" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="20641" />
  </DataNode>
  <DataNode TextLabel="Ddx19b" GraphId="ab4" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Ddx19b | DEAD (Asp-Glu-Ala-Asp) box polypeptide..." />
    <Graphics CenterX="1483.3333333333333" CenterY="1626.6666666666667" Width="106.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="234733" />
  </DataNode>
  <DataNode TextLabel="4930554P13Rik" GraphId="ab8" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="RIKEN cDNA 4930554P13 gene" />
    <Graphics CenterX="370.0" CenterY="1330.0" Width="106.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="MGI" ID="MGI:1922548" />
  </DataNode>
  <DataNode TextLabel="Snrpa" GraphId="ab9" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Snrpa | small nuclear ribonucleoprotein polypep..." />
    <Graphics CenterX="576.6666666666666" CenterY="223.33333333333334" Width="73.33333333333333" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="53607" />
  </DataNode>
  <DataNode TextLabel="Pabpc5" GraphId="aba" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pabpc5 | poly A binding protein cytoplasmic 5..." />
    <Graphics CenterX="953.3333333333334" CenterY="1526.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="93728" />
  </DataNode>
  <DataNode TextLabel="Eif3s4" GraphId="abc" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Eif3s4 | eukaryotic translation initiation fac..." />
    <Graphics CenterX="810.0" CenterY="1486.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="53356" />
  </DataNode>
  <DataNode TextLabel="Sfrs11" GraphId="abd" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Sfrs11 | splicing factor arginine/serine-rich..." />
    <Graphics CenterX="2000.0" CenterY="883.3333333333334" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="69207" />
  </DataNode>
  <DataNode TextLabel="AW553050" GraphId="abe" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="expressed sequence AW553050" />
    <Graphics CenterX="670.0" CenterY="1210.0" Width="73.33333333333333" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="MGI" ID="MGI:2142260" />
  </DataNode>
  <DataNode TextLabel="Snrpb" GraphId="ac4" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Snrpb | small nuclear ribonucleoprotein B" />
    <Graphics CenterX="576.6666666666666" CenterY="266.6666666666667" Width="73.33333333333333" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="20638" />
  </DataNode>
  <DataNode TextLabel="Ewsr1" GraphId="ac5" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Ewsr1 | Ewing sarcoma breakpoint region 1" />
    <Graphics CenterX="810.0" CenterY="1546.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="14030" />
  </DataNode>
  <DataNode TextLabel="Smn1" GraphId="ac6" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Smn1 | survival motor neuron 1" />
    <Graphics CenterX="2000.0" CenterY="923.3333333333334" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="20595" />
  </DataNode>
  <DataNode TextLabel="MGI:2387367" GraphId="ac8" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="MGI:2387367 | developmentally regulated RNA bin..." />
    <Graphics CenterX="810.0" CenterY="1306.6666666666667" Width="100.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="241490" />
  </DataNode>
  <DataNode TextLabel="2810055E05Rik" GraphId="acd" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="2810055E05Rik | RIKEN cDNA 2810055E05 gene" />
    <Graphics CenterX="1773.3333333333333" CenterY="1626.6666666666667" Width="95.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="230780" />
  </DataNode>
  <DataNode TextLabel="BB131279" GraphId="ad0" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="BB131279 | expressed sequence BB131279" />
    <Graphics CenterX="670.0" CenterY="1230.0" Width="66.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="103061" />
  </DataNode>
  <DataNode TextLabel="Exosc7" GraphId="ad6" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Exosc7 | exosome component 7" />
    <Graphics CenterX="1483.3333333333333" CenterY="1446.6666666666667" Width="106.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="66446" />
  </DataNode>
  <DataNode TextLabel="Cstf3" GraphId="ad8" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Cstf3 | cleavage stimulation factor 3â pre-RN..." />
    <Graphics CenterX="1536.6666666666667" CenterY="193.33333333333334" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="228410" />
  </DataNode>
  <DataNode TextLabel="Rps28" GraphId="ada" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Rps28 | ribosomal protein S28" />
    <Graphics CenterX="1906.6666666666667" CenterY="1443.3333333333333" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="54127" />
  </DataNode>
  <DataNode TextLabel="PRP17_MOUSE" GraphId="add" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="prp17" />
    <Graphics CenterX="1060.0" CenterY="480.0" Width="53.333333333333336" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Uniprot-TrEMBL" ID="Q9DC48" />
  </DataNode>
  <DataNode TextLabel="Oas1a" GraphId="adf" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Oas1a | 2â-5â oligoadenylate synthetase 1A" />
    <Graphics CenterX="1773.3333333333333" CenterY="1346.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="246730" />
  </DataNode>
  <DataNode TextLabel="Sbno1" GraphId="ae2" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Sbno1 | sno strawberry notch homolog 1 (Droso..." />
    <Graphics CenterX="1066.6666666666667" CenterY="1546.6666666666667" Width="66.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="243272" />
  </DataNode>
  <DataNode TextLabel="Rpl9" GraphId="ae8" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Rpl9 | ribosomal protein L9" />
    <Graphics CenterX="1906.6666666666667" CenterY="1283.3333333333333" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="20005" />
  </DataNode>
  <DataNode TextLabel="Papolg" GraphId="aed" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Papolg | poly(A) polymerase gamma" />
    <Graphics CenterX="1483.3333333333333" CenterY="1766.6666666666667" Width="106.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="216578" />
  </DataNode>
  <DataNode TextLabel="Sf4" GraphId="aee" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">inferred from: SURP 2, G patch protein, UniProt:O60378</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Sf4 | splicing factor 4" />
    <Graphics CenterX="966.6666666666666" CenterY="290.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="70616" />
  </DataNode>
  <DataNode TextLabel="Prkr" GraphId="af0" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Prkr | protein kinase interferon-inducible do..." />
    <Graphics CenterX="1773.3333333333333" CenterY="1606.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="19106" />
  </DataNode>
  <DataNode TextLabel="B930007L02Rik" GraphId="af7" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="B930007L02Rik | RIKEN cDNA B930007L02 gene" />
    <Graphics CenterX="670.0" CenterY="1330.0" Width="103.33333333333333" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="321006" />
  </DataNode>
  <DataNode TextLabel="MGI:1926224" GraphId="b00" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="MGI:1926224 | ataxin 2 binding protein 1" />
    <Graphics CenterX="670.0" CenterY="1670.0" Width="103.33333333333333" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="268859" />
  </DataNode>
  <DataNode TextLabel="Bclaf1" GraphId="b09" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Bclaf1 | BCL2-associated transcription factor 1..." />
    <Graphics CenterX="216.66666666666666" CenterY="1410.0" Width="106.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="72567" />
  </DataNode>
  <DataNode TextLabel="Ppie" GraphId="b0a" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Ppie | peptidylprolyl isomerase E (cyclophilin ..." />
    <Graphics CenterX="953.3333333333334" CenterY="1406.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="56031" />
  </DataNode>
  <DataNode TextLabel="Rnaseh2a" GraphId="b0d" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Rnaseh2a | ribonuclease H2 large subunit" />
    <Graphics CenterX="1483.3333333333333" CenterY="1406.6666666666667" Width="106.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="69724" />
  </DataNode>
  <DataNode TextLabel="Rnu1b2" GraphId="b0f" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Rnu1b2 | U1b2 small nuclear RNA" />
    <Graphics CenterX="670.0" CenterY="223.33333333333334" Width="73.33333333333333" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="19845" />
  </DataNode>
  <DataNode TextLabel="AI256346" GraphId="b10" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="AI256346 | expressed sequence AI256346" />
    <Graphics CenterX="516.6666666666666" CenterY="1490.0" Width="63.333333333333336" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="105123" />
  </DataNode>
  <DataNode TextLabel="Tiaf1" GraphId="b11" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Tiaf1 | TGF-beta1-induced anti-apoptotic factor..." />
    <Graphics CenterX="1066.6666666666667" CenterY="1706.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="21842" />
  </DataNode>
  <DataNode TextLabel="Rpl39" GraphId="b12" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Rpl39 | ribosomal protein L39" />
    <Graphics CenterX="1906.6666666666667" CenterY="1223.3333333333333" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="67248" />
  </DataNode>
  <DataNode TextLabel="Rad21" GraphId="b13" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Rad21 | RAD21 homolog (S. pombe)" />
    <Graphics CenterX="1773.3333333333333" CenterY="1703.3333333333333" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="19357" />
  </DataNode>
  <DataNode TextLabel="Fxr2h" GraphId="b15" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Fxr2h | fragile X mental retardation gene 2 a..." />
    <Graphics CenterX="1636.6666666666667" CenterY="1806.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="23879" />
  </DataNode>
  <DataNode TextLabel="C85084" GraphId="b18" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="expressed sequence C85084" />
    <Graphics CenterX="670.0" CenterY="1470.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="MGI" ID="MGI:2140695" />
  </DataNode>
  <DataNode TextLabel="Adarb2" GraphId="b1b" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Adarb2 | adenosine deaminase RNA-specific B2..." />
    <Graphics CenterX="1636.6666666666667" CenterY="1166.6666666666667" Width="100.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="94191" />
  </DataNode>
  <DataNode TextLabel="Sfpq" GraphId="b1c" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Sfpq | splicing factor proline/glutamine rich (..." />
    <Graphics CenterX="2000.0" CenterY="903.3333333333334" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="71514" />
  </DataNode>
  <DataNode TextLabel="Fus" GraphId="b1e" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Fus | fusion derived from t(12;16) malignant ..." />
    <Graphics CenterX="966.6666666666666" CenterY="250.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="233908" />
  </DataNode>
  <DataNode TextLabel="Sfrs8" GraphId="b20" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Sfrs8 | splicing factor arginine/serine-rich ..." />
    <Graphics CenterX="1616.6666666666667" CenterY="786.6666666666666" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="231769" />
  </DataNode>
  <DataNode TextLabel="Pskh1" GraphId="b21" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">PMID: 12466556</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pskh1 | protein serine kinase H1" />
    <Graphics CenterX="1616.6666666666667" CenterY="686.6666666666666" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="244631" />
  </DataNode>
  <DataNode TextLabel="Ppp1r8" GraphId="b25" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Ppp1r8 | protein phosphatase 1 regulatory (in..." />
    <Graphics CenterX="1483.3333333333333" CenterY="1746.6666666666667" Width="106.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="100336" />
  </DataNode>
  <DataNode TextLabel="Cd2bp2" GraphId="b28" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Cd2bp2 | CD2 antigen (cytoplasmic tail) binding..." />
    <Graphics CenterX="1053.3333333333333" CenterY="270.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="70233" />
  </DataNode>
  <DataNode TextLabel="Lrrn6a" GraphId="b29" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Lrrn6a | leucine rich repeat neuronal 6A" />
    <Graphics CenterX="370.0" CenterY="1290.0" Width="106.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="235402" />
  </DataNode>
  <DataNode TextLabel="0610009C03Rik" GraphId="b30" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="0610009C03Rik | RIKEN cDNA 0610009C03 gene" />
    <Graphics CenterX="796.6666666666666" CenterY="663.3333333333334" Width="73.33333333333333" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="66585" />
  </DataNode>
  <DataNode TextLabel="Rps23" GraphId="b32" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Rps23 | ribosomal protein S23" />
    <Graphics CenterX="1906.6666666666667" CenterY="1383.3333333333333" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="66475" />
  </DataNode>
  <DataNode TextLabel="Papola" GraphId="b37" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Papola | poly (A) polymerase alpha" />
    <Graphics CenterX="1423.3333333333333" CenterY="183.33333333333334" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="18789" />
  </DataNode>
  <DataNode TextLabel="Sfrs9" GraphId="b38" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">PMID: 12738786, PMID: 12024014  (associated with hnRNP A1 splicing)</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Sfrs9 | splicing factor arginine/serine rich ..." />
    <Graphics CenterX="863.3333333333334" CenterY="290.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="108014" />
  </DataNode>
  <DataNode TextLabel="Rbmy1a1" GraphId="b3c" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Rbmy1a1 | RNA binding motif protein Y chromos..." />
    <Graphics CenterX="1066.6666666666667" CenterY="1206.6666666666667" Width="66.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="19657" />
  </DataNode>
  <DataNode TextLabel="Hnrpa3" GraphId="b3f" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Hnrpa3 | heterogeneous nuclear ribonucleoprotei..." />
    <Graphics CenterX="323.3333333333333" CenterY="353.3333333333333" Width="69.33333333333333" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="229279" />
  </DataNode>
  <DataNode TextLabel="Ddx3x" GraphId="b41" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Ddx3x | DEAD/H (Asp-Glu-Ala-Asp/His) box polyp..." />
    <Graphics CenterX="1636.6666666666667" CenterY="1526.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="13205" />
  </DataNode>
  <DataNode TextLabel="Bard1" GraphId="b44" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Bard1 | BRCA1 associated RING domain 1" />
    <Graphics CenterX="1636.6666666666667" CenterY="1246.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="12021" />
  </DataNode>
  <DataNode TextLabel="Prpf4" GraphId="b46" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Prpf4 | PRP4 pre-mRNA processing factor 4 homol..." />
    <Graphics CenterX="596.6666666666666" CenterY="666.6666666666666" Width="73.33333333333333" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="70052" />
  </DataNode>
  <DataNode TextLabel="Zbp1" GraphId="b47" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Zbp1 | Z-DNA binding protein 1" />
    <Graphics CenterX="2030.0" CenterY="1226.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="58203" />
  </DataNode>
  <DataNode TextLabel="4932422M17Rik" GraphId="b4a" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="4932422M17Rik | RIKEN cDNA 4932422M17 gene" />
    <Graphics CenterX="370.0" CenterY="1430.0" Width="100.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="74366" />
  </DataNode>
  <DataNode TextLabel="AW049977" GraphId="b4c" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="expressed sequence AW049977" />
    <Graphics CenterX="670.0" CenterY="1150.0" Width="73.33333333333333" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="MGI" ID="MGI:2142752" />
  </DataNode>
  <DataNode TextLabel="Dazl" GraphId="b4d" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Dazl | deleted in azoospermia-like" />
    <Graphics CenterX="810.0" CenterY="1286.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="13164" />
  </DataNode>
  <DataNode TextLabel="Pum1" GraphId="b4e" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pum1 | pumilio 1 (Drosophila)" />
    <Graphics CenterX="1773.3333333333333" CenterY="1646.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="80912" />
  </DataNode>
  <DataNode TextLabel="AI255230" GraphId="b55" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="AI255230 | expressed sequence AI255230" />
    <Graphics CenterX="516.6666666666666" CenterY="1390.0" Width="63.333333333333336" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="98285" />
  </DataNode>
  <DataNode TextLabel="1700003D06Rik" GraphId="b59" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="RIKEN cDNA 1700003D06 gene" />
    <Graphics CenterX="70.0" CenterY="1430.0" Width="100.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="MGI" ID="MGI:1919466" />
  </DataNode>
  <DataNode TextLabel="Prpf4b" GraphId="b5a" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Prpf4b | PRP4 pre-mRNA processing factor 4 homo..." />
    <Graphics CenterX="1616.6666666666667" CenterY="626.6666666666666" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="19134" />
  </DataNode>
  <DataNode TextLabel="Ciz1" GraphId="b5b" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Ciz1 | CDKN1A interacting zinc finger protein 1..." />
    <Graphics CenterX="1636.6666666666667" CenterY="1326.6666666666667" Width="100.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="68379" />
  </DataNode>
  <DataNode TextLabel="AI043106" GraphId="b5c" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="expressed sequence AI043106" />
    <Graphics CenterX="516.6666666666666" CenterY="1230.0" Width="63.333333333333336" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="103625" />
  </DataNode>
  <DataNode TextLabel="Cugbp2" GraphId="b5d" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Cugbp2 | CUG triplet repeatRNA binding protei..." />
    <Graphics CenterX="1816.6666666666667" CenterY="696.6666666666666" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="14007" />
  </DataNode>
  <DataNode TextLabel="Igf2bp1" GraphId="b5e" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Igf2bp1 | insulin-like growth factor 2 bindin..." />
    <Graphics CenterX="810.0" CenterY="1746.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="140486" />
  </DataNode>
  <DataNode TextLabel="Rnu12" GraphId="b61" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Rnu12 | RNA U12 small nuclear" />
    <Graphics CenterX="1066.6666666666667" CenterY="1366.6666666666667" Width="66.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="104307" />
  </DataNode>
  <DataNode TextLabel="Spen" GraphId="b64" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Spen | SPEN homolog transcriptional regulator..." />
    <Graphics CenterX="953.3333333333334" CenterY="1206.6666666666667" Width="93.33333333333333" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="56381" />
  </DataNode>
  <DataNode TextLabel="2610027L16Rik" GraphId="b67" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="2610027L16Rik | RIKEN cDNA 2610027L16 gene" />
    <Graphics CenterX="1483.3333333333333" CenterY="1486.6666666666667" Width="106.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="67842" />
  </DataNode>
  <DataNode TextLabel="Rpl22" GraphId="b68" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Rpl22 | ribosomal protein L22" />
    <Graphics CenterX="1906.6666666666667" CenterY="1146.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="19934" />
  </DataNode>
  <DataNode TextLabel="Mki67ip" GraphId="b69" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Mki67ip | Mki67 (FHA domain) interacting nucleo..." />
    <Graphics CenterX="953.3333333333334" CenterY="1186.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="67949" />
  </DataNode>
  <DataNode TextLabel="U4 snRNA" GraphId="b6a" Type="Rna">
    <Comment Source="GenMAPP remarks">GenBank sequence: M10328, M18004</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="U4 snRNA" />
    <Graphics CenterX="596.6666666666666" CenterY="626.6666666666666" Width="73.33333333333333" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Other" ID="M10328" />
  </DataNode>
  <DataNode TextLabel="Rnu1b1" GraphId="b6b" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Rnu1b1 | U1b1 small nuclear RNA" />
    <Graphics CenterX="1066.6666666666667" CenterY="1446.6666666666667" Width="66.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="19844" />
  </DataNode>
  <DataNode TextLabel="Rnpc1" GraphId="b6e" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Rnpc1 | RNA-binding region (RNP1 RRM) contain..." />
    <Graphics CenterX="1066.6666666666667" CenterY="1326.6666666666667" Width="66.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="56190" />
  </DataNode>
  <DataNode TextLabel="Ddx48" GraphId="b72" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Ddx48 | DEAD (Asp-Glu-Ala-Asp) box polypeptide ..." />
    <Graphics CenterX="1636.6666666666667" CenterY="1586.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="192170" />
  </DataNode>
  <DataNode TextLabel="3110061K15Rik" GraphId="b73" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="RIKEN cDNA 3110061K15 gene" />
    <Graphics CenterX="216.66666666666666" CenterY="1790.0" Width="106.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="MGI" ID="MGI:1920450" />
  </DataNode>
  <DataNode TextLabel="1110033J19Rik" GraphId="b74" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="1110033J19Rik | RIKEN cDNA 1110033J19 gene" />
    <Graphics CenterX="1483.3333333333333" CenterY="1206.6666666666667" Width="106.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="66184" />
  </DataNode>
  <DataNode TextLabel="Matr3-ps1" GraphId="b76" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Matr3-ps1 | matrin 3 pseudogene 1" />
    <Graphics CenterX="953.3333333333334" CenterY="1146.6666666666667" Width="66.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="17185" />
  </DataNode>
  <DataNode TextLabel="Srp68" GraphId="b77" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Srp68 | signal recognition particle 68" />
    <Graphics CenterX="1483.3333333333333" CenterY="1466.6666666666667" Width="106.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="217337" />
  </DataNode>
  <DataNode TextLabel="Ptbp2" GraphId="b78" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Ptbp2 | polypyrimidine tract binding protein 2" />
    <Graphics CenterX="1816.6666666666667" CenterY="716.6666666666666" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="56195" />
  </DataNode>
  <DataNode TextLabel="Rbm11" GraphId="b79" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Rbm11 | RNA binding motif protein 11" />
    <Graphics CenterX="953.3333333333334" CenterY="1726.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="224344" />
  </DataNode>
  <DataNode TextLabel="2610031L17Rik" GraphId="b7d" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="2610031L17Rik | RIKEN cDNA 2610031L17 gene" />
    <Graphics CenterX="796.6666666666666" CenterY="683.3333333333334" Width="73.33333333333333" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="68879" />
  </DataNode>
  <DataNode TextLabel="Ddx39" GraphId="b7e" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Ddx39 | DEAD (Asp-Glu-Ala-Asp) box polypeptide ..." />
    <Graphics CenterX="1636.6666666666667" CenterY="1506.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="68278" />
  </DataNode>
  <DataNode TextLabel="2010003O18Rik" GraphId="b7f" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="2010003O18Rik | RIKEN cDNA 2010003O18 gene" />
    <Graphics CenterX="1483.3333333333333" CenterY="1326.6666666666667" Width="106.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="384281" />
  </DataNode>
  <DataNode TextLabel="1110037F02Rik" GraphId="b81" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="1110037F02Rik | RIKEN cDNA 1110037F02 gene" />
    <Graphics CenterX="70.0" CenterY="1290.0" Width="100.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="66185" />
  </DataNode>
  <DataNode TextLabel="Pabpc1" GraphId="b84" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pabpc1 | poly A binding protein cytoplasmic 1..." />
    <Graphics CenterX="953.3333333333334" CenterY="1466.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="18458" />
  </DataNode>
  <DataNode TextLabel="Ddx41" GraphId="b85" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Ddx41 | DEAD (Asp-Glu-Ala-Asp) box polypeptide ..." />
    <Graphics CenterX="1636.6666666666667" CenterY="1566.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="72935" />
  </DataNode>
  <DataNode TextLabel="Elavl1" GraphId="b92" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Elavl1 | ELAV (embryonic lethal abnormal visi..." />
    <Graphics CenterX="810.0" CenterY="1386.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="15568" />
  </DataNode>
  <DataNode TextLabel="Snrp1c" GraphId="b95" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Snrp1c | U1 small nuclear ribonucleoprotein 1C" />
    <Graphics CenterX="1906.6666666666667" CenterY="1623.3333333333333" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="20630" />
  </DataNode>
  <DataNode TextLabel="Cstf1" GraphId="b96" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Cstf1 | cleavage stimulation factor 3â pre-RN..." />
    <Graphics CenterX="1536.6666666666667" CenterY="133.33333333333334" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="67337" />
  </DataNode>
  <DataNode TextLabel="G3bp2-pending" GraphId="b9a" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Ras-GTPase-activating protein (GAP&lt;120&gt;) SH3-domai" />
    <Graphics CenterX="810.0" CenterY="1566.6666666666667" Width="106.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="MGI" ID="MGI:1346339" />
  </DataNode>
  <DataNode TextLabel="Stau1" GraphId="b9b" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Stau1 | staufen (RNA binding protein) homolog 1..." />
    <Graphics CenterX="1906.6666666666667" CenterY="1763.3333333333333" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="20853" />
  </DataNode>
  <DataNode TextLabel="Snrp70" GraphId="b9d" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Snrp70 | U1 small nuclear ribonucleoprotein pol..." />
    <Graphics CenterX="576.6666666666666" CenterY="203.33333333333334" Width="73.33333333333333" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="20637" />
  </DataNode>
  <DataNode TextLabel="2610209F03Rik" GraphId="b9e" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="RIKEN cDNA 2610209F03 gene" />
    <Graphics CenterX="216.66666666666666" CenterY="1450.0" Width="106.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="MGI" ID="MGI:2149675" />
  </DataNode>
  <DataNode TextLabel="Snrpb2" GraphId="ba1" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Snrpb2 | U2 small nuclear ribonucleoprotein B" />
    <Graphics CenterX="700.0" CenterY="446.6666666666667" Width="66.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="20639" />
  </DataNode>
  <DataNode TextLabel="4930534J06Rik" GraphId="ba3" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="4930534J06Rik" />
    <Graphics CenterX="1483.3333333333333" CenterY="1726.6666666666667" Width="106.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="MGI" ID="MGI:2442955" />
  </DataNode>
  <DataNode TextLabel="Matr3" GraphId="ba5" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Matr3 | matrin 3" />
    <Graphics CenterX="810.0" CenterY="1806.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="17184" />
  </DataNode>
  <DataNode TextLabel="0610009J05Rik" GraphId="ba7" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="RIKEN cDNA 0610009J05 gene" />
    <Graphics CenterX="70.0" CenterY="1170.0" Width="100.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="MGI" ID="MGI:1921339" />
  </DataNode>
  <DataNode TextLabel="Clk2" GraphId="ba8" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Clk2 | CDC-like kinase 2" />
    <Graphics CenterX="1616.6666666666667" CenterY="566.6666666666666" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="12748" />
  </DataNode>
  <DataNode TextLabel="Cugbp1" GraphId="bab" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Cugbp1 | CUG triplet repeat RNA binding prote..." />
    <Graphics CenterX="2000.0" CenterY="703.3333333333334" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="13046" />
  </DataNode>
  <DataNode TextLabel="Refbp2" GraphId="bae" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Refbp2 | RNA and export factor binding protein ..." />
    <Graphics CenterX="1066.6666666666667" CenterY="1286.6666666666667" Width="66.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="56009" />
  </DataNode>
  <DataNode TextLabel="D12Mgi43" GraphId="bb0" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="D12Mgi43 | DNA Segment Chr 12 Mouse Genome I..." />
    <Graphics CenterX="516.6666666666666" CenterY="1750.0" Width="66.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="104924" />
  </DataNode>
  <DataNode TextLabel="2410003C20Rik" GraphId="bb1" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="2410003C20Rik | RIKEN cDNA 2410003C20 gene" />
    <Graphics CenterX="1483.3333333333333" CenterY="1426.6666666666667" Width="106.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="66983" />
  </DataNode>
  <DataNode TextLabel="Dnajc8" GraphId="bb2" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Dnajc8 | DnaJ (Hsp40) homolog subfamily C me..." />
    <Graphics CenterX="1060.0" CenterY="440.0" Width="53.333333333333336" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="68598" />
  </DataNode>
  <DataNode TextLabel="Nhp2l1" GraphId="bb4" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Nhp2l1" />
    <Graphics CenterX="906.6666666666666" CenterY="663.3333333333334" Width="73.33333333333333" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Uniprot-TrEMBL" ID="Q9D0T1" />
  </DataNode>
  <DataNode TextLabel="U2af1-rs1" GraphId="bb5" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="U2af1-rs1 | U2 small nuclear ribonucleoprotein..." />
    <Graphics CenterX="1066.6666666666667" CenterY="1806.6666666666667" Width="66.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="22183" />
  </DataNode>
  <DataNode TextLabel="Ddx1" GraphId="bb8" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Ddx1 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 1..." />
    <Graphics CenterX="1816.6666666666667" CenterY="546.6666666666666" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="104721" />
  </DataNode>
  <DataNode TextLabel="B230333C21Rik" GraphId="bb9" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="B230333C21Rik | RIKEN cDNA B230333C21 gene" />
    <Graphics CenterX="670.0" CenterY="1310.0" Width="103.33333333333333" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="338351" />
  </DataNode>
  <DataNode TextLabel="Sart3" GraphId="bba" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Sart3 | squamous cell carcinoma antigen recogni..." />
    <Graphics CenterX="1066.6666666666667" CenterY="1606.6666666666667" Width="66.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="53890" />
  </DataNode>
  <DataNode TextLabel="Col4a3" GraphId="bbb" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Col4a3 | procollagen type IV alpha 3" />
    <Graphics CenterX="670.0" CenterY="1790.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="12828" />
  </DataNode>
  <DataNode TextLabel="H2-Bf" GraphId="bbf" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="H2-Bf | histocompatibility 2 complement compo..." />
    <Graphics CenterX="810.0" CenterY="1686.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="14962" />
  </DataNode>
  <DataNode TextLabel="Sf3b2" GraphId="bc8" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Sf3b2 | splicing factor 3b subunit 2" />
    <Graphics CenterX="806.6666666666666" CenterY="446.6666666666667" Width="66.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="319322" />
  </DataNode>
  <DataNode TextLabel="Rnu6" GraphId="bca" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">GenBank sequence: M10329</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Rnu6 | U6 small nuclear RNA" />
    <Graphics CenterX="696.6666666666666" CenterY="623.3333333333334" Width="73.33333333333333" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="19862" />
  </DataNode>
  <DataNode TextLabel="G430095G15Rik" GraphId="bcb" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="RIKEN cDNA G430095G15 gene" />
    <Graphics CenterX="670.0" CenterY="1590.0" Width="106.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="MGI" ID="MGI:2443869" />
  </DataNode>
  <DataNode TextLabel="Mrps28" GraphId="bcf" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Mrps28 | mitochondrial ribosomal protein S28" />
    <Graphics CenterX="1773.3333333333333" CenterY="1226.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="66230" />
  </DataNode>
  <DataNode TextLabel="Ncbp2" GraphId="bd1" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Ncbp2 | nuclear cap binding protein subunit 2" />
    <Graphics CenterX="366.6666666666667" CenterY="223.33333333333334" Width="48.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="68092" />
  </DataNode>
  <DataNode TextLabel="Eif4a2" GraphId="bd3" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Eif4a2 | eukaryotic translation initiation fact..." />
    <Graphics CenterX="1636.6666666666667" CenterY="1686.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="13682" />
  </DataNode>
  <DataNode TextLabel="Dhx9" GraphId="bd5" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Dhx9 | DEAH (Asp-Glu-Ala-His) box polypeptide 9..." />
    <Graphics CenterX="1013.3333333333334" CenterY="190.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="13211" />
  </DataNode>
  <DataNode TextLabel="Ddx24" GraphId="bd7" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Ddx24 | DEAD (Asp-Glu-Ala-Asp) box polypeptide ..." />
    <Graphics CenterX="1636.6666666666667" CenterY="1466.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="27225" />
  </DataNode>
  <DataNode TextLabel="4930565A21Rik" GraphId="bda" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="4930565A21Rik | RIKEN cDNA 4930565A21 gene" />
    <Graphics CenterX="370.0" CenterY="1370.0" Width="106.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="319586" />
  </DataNode>
  <DataNode TextLabel="Fnbp3" GraphId="bdb" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Fnbp3 | formin binding protein 3" />
    <Graphics CenterX="2000.0" CenterY="823.3333333333334" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="56194" />
  </DataNode>
  <DataNode TextLabel="Wdr55" GraphId="bdd" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Wdr55 | WD repeat domain 55" />
    <Graphics CenterX="70.0" CenterY="1810.0" Width="100.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="67936" />
  </DataNode>
  <DataNode TextLabel="Brunol4" GraphId="be2" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Brunol4 | bruno-like 4 RNA binding protein (D..." />
    <Graphics CenterX="1816.6666666666667" CenterY="676.6666666666666" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="108013" />
  </DataNode>
  <DataNode TextLabel="Ppargc1a" GraphId="be3" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Ppargc1a | peroxisome proliferative activated ..." />
    <Graphics CenterX="953.3333333333334" CenterY="1426.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="19017" />
  </DataNode>
  <DataNode TextLabel="Htatsf1" GraphId="be4" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Htatsf1 | HIV TAT specific factor 1" />
    <Graphics CenterX="216.66666666666666" CenterY="1270.0" Width="100.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="72459" />
  </DataNode>
  <DataNode TextLabel="Sfrs12" GraphId="be5" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Sfrs12 | splicing factor arginine/serine-rich..." />
    <Graphics CenterX="516.6666666666666" CenterY="1570.0" Width="63.333333333333336" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="218543" />
  </DataNode>
  <DataNode TextLabel="D19Bwg1357e" GraphId="be7" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="D19Bwg1357e | DNA segment Chr 19 Brigham &amp; W..." />
    <Graphics CenterX="670.0" CenterY="1510.0" Width="106.6634" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="52874" />
  </DataNode>
  <DataNode TextLabel="4930517K11Rik" GraphId="bed" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="4930517K11Rik | RIKEN cDNA 4930517K11 gene" />
    <Graphics CenterX="1483.3333333333333" CenterY="1706.6666666666667" Width="106.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="68172" />
  </DataNode>
  <DataNode TextLabel="Snrpn" GraphId="bf0" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Snrpn | small nuclear ribonucleoprotein N" />
    <Graphics CenterX="1816.6666666666667" CenterY="873.3333333333334" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="20646" />
  </DataNode>
  <DataNode TextLabel="Cdc40" GraphId="bf4" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Cdc40 | cell division cycle 40 homolog (yeast)" />
    <Graphics CenterX="1060.0" CenterY="420.0" Width="53.333333333333336" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="71713" />
  </DataNode>
  <DataNode TextLabel="Taf15" GraphId="bf5" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Taf15 | TAF15 RNA polymerase II TATA box bind..." />
    <Graphics CenterX="1066.6666666666667" CenterY="1646.6666666666667" Width="66.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="70439" />
  </DataNode>
  <DataNode TextLabel="Sfrs1" GraphId="bf6" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Antagonist splicing factor</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Sfrs1 | splicing factor arginine/serine-rich ..." />
    <Graphics CenterX="773.3333333333334" CenterY="250.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="110809" />
  </DataNode>
  <DataNode TextLabel="2010319N22Rik" GraphId="bf7" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="RIKEN cDNA 2010319N22 gene" />
    <Graphics CenterX="70.0" CenterY="1670.0" Width="100.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="MGI" ID="MGI:1917273" />
  </DataNode>
  <DataNode TextLabel="Cdk9" GraphId="bf8" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Cdk9 | cyclin-dependent kinase 9 (CDC2-related ..." />
    <Graphics CenterX="670.0" CenterY="1770.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="107951" />
  </DataNode>
  <DataNode TextLabel="Hnrpa3" GraphId="bf9" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Hnrpa3 | heterogeneous nuclear ribonucleoprotei..." />
    <Graphics CenterX="216.66666666666666" CenterY="1470.0" Width="106.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="229279" />
  </DataNode>
  <DataNode TextLabel="C430048L16Rik" GraphId="bfc" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="C430048L16Rik | RIKEN cDNA C430048L16 gene" />
    <Graphics CenterX="670.0" CenterY="1410.0" Width="103.33333333333333" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="77604" />
  </DataNode>
  <DataNode TextLabel="2700088M22Rik" GraphId="bfe" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="2700088M22Rik | RIKEN cDNA 2700088M22 gene" />
    <Graphics CenterX="216.66666666666666" CenterY="1570.0" Width="106.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="67197" />
  </DataNode>
  <DataNode TextLabel="Bicc1" GraphId="bff" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Bicc1 | bicaudal C homolog 1 (Drosophila)" />
    <Graphics CenterX="1636.6666666666667" CenterY="1286.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="83675" />
  </DataNode>
  <DataNode TextLabel="2010300K22Rik" GraphId="c00" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="RIKEN cDNA 2010300K22 gene" />
    <Graphics CenterX="70.0" CenterY="1650.0" Width="100.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="MGI" ID="MGI:1913726" />
  </DataNode>
  <DataNode TextLabel="Rnu1a1" GraphId="c01" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">GenBank sequence: J00645</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Rnu1a1 | U1a1 small nuclear RNA" />
    <Graphics CenterX="576.6666666666666" CenterY="183.33333333333334" Width="73.33333333333333" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="19842" />
  </DataNode>
  <DataNode TextLabel="Ppp1r14b" GraphId="c03" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Ppp1r14b | protein phosphatase 1 regulatory (..." />
    <Graphics CenterX="953.3333333333334" CenterY="1586.6666666666667" Width="66.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="18938" />
  </DataNode>
  <DataNode TextLabel="Rps29" GraphId="c04" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Rps29 | ribosomal protein S29" />
    <Graphics CenterX="1906.6666666666667" CenterY="1463.3333333333333" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="20090" />
  </DataNode>
  <DataNode TextLabel="Sfrs4" GraphId="c08" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Sfrs4 | splicing factor arginine/serine-rich ..." />
    <Graphics CenterX="933.3333333333334" CenterY="420.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="57317" />
  </DataNode>
  <DataNode TextLabel="Dhx8" GraphId="c09" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Dhx8 | DEAH (Asp-Glu-Ala-His) box polypeptide 8..." />
    <Graphics CenterX="1816.6666666666667" CenterY="586.6666666666666" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="217207" />
  </DataNode>
  <DataNode TextLabel="Rbm12" GraphId="c0a" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Rbm12 | RNA binding motif protein 12" />
    <Graphics CenterX="953.3333333333334" CenterY="1746.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="75710" />
  </DataNode>
  <DataNode TextLabel="Rnu1b1" GraphId="c0b" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Rnu1b1 | U1b1 small nuclear RNA" />
    <Graphics CenterX="670.0" CenterY="203.33333333333334" Width="73.33333333333333" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="19844" />
  </DataNode>
  <DataNode TextLabel="2410112D09Rik" GraphId="c0f" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="RIKEN cDNA 2410112D09 gene" />
    <Graphics CenterX="216.66666666666666" CenterY="1170.0" Width="100.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="MGI" ID="MGI:1920919" />
  </DataNode>
  <DataNode TextLabel="Dkc1" GraphId="c10" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Dkc1 | dyskeratosis congenita 1dyskerin homol..." />
    <Graphics CenterX="1636.6666666666667" CenterY="1666.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="108025" />
  </DataNode>
  <DataNode TextLabel="D9Mgi24" GraphId="c11" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="D9Mgi24 | DNA Segment Chr 9 Mouse Genome Inf..." />
    <Graphics CenterX="516.6666666666666" CenterY="1410.0" Width="63.333333333333336" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="102460" />
  </DataNode>
  <DataNode TextLabel="9630048M01Rik" GraphId="c12" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="9630048M01Rik | RIKEN cDNA 9630048M01 gene" />
    <Graphics CenterX="1483.3333333333333" CenterY="1786.6666666666667" Width="106.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="320158" />
  </DataNode>
  <DataNode TextLabel="AI462438" GraphId="c15" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="AI462438 | expressed sequence AI462438" />
    <Graphics CenterX="1213.3333333333333" CenterY="176.66666666666666" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="98985" />
  </DataNode>
  <DataNode TextLabel="B230118G17Rik" GraphId="c19" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="RIKEN cDNA B230118G17 gene" />
    <Graphics CenterX="670.0" CenterY="1290.0" Width="103.33333333333333" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="MGI" ID="MGI:1915415" />
  </DataNode>
  <DataNode TextLabel="Ilf3" GraphId="c1a" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Ilf3 | interleukin enhancer binding factor 3" />
    <Graphics CenterX="1773.3333333333333" CenterY="1146.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="16201" />
  </DataNode>
  <DataNode TextLabel="Hnrpk" GraphId="c1c" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Hnrpk | heterogeneous nuclear ribonucleoprotein..." />
    <Graphics CenterX="423.3333333333333" CenterY="373.3333333333333" Width="66.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="15387" />
  </DataNode>
  <DataNode TextLabel="Tial1" GraphId="c1f" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Tial1 | Tial1 cytotoxic granule-associated RNA ..." />
    <Graphics CenterX="1066.6666666666667" CenterY="1726.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="21843" />
  </DataNode>
  <DataNode TextLabel="D230005D02Rik" GraphId="c22" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="D230005D02Rik | RIKEN cDNA D230005D02 gene" />
    <Graphics CenterX="670.0" CenterY="1530.0" Width="106.6634" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="239188" />
  </DataNode>
  <DataNode TextLabel="Ppil4" GraphId="c26" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Ppil4 | peptidylprolyl isomerase (cyclophilin)-..." />
    <Graphics CenterX="953.3333333333334" CenterY="1386.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="67418" />
  </DataNode>
  <DataNode TextLabel="9530027K23Rik" GraphId="c27" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="9530027K23Rik | RIKEN cDNA 9530027K23 gene" />
    <Graphics CenterX="370.0" CenterY="1790.0" Width="100.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="77411" />
  </DataNode>
  <DataNode TextLabel="Zfp622" GraphId="c2b" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Zfp622 | zinc finger protein 622" />
    <Graphics CenterX="670.0" CenterY="1490.0" Width="106.6634" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="52521" />
  </DataNode>
  <DataNode TextLabel="Prpf8" GraphId="c2e" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Prpf8 | pre-mRNA processing factor 8" />
    <Graphics CenterX="1060.0" CenterY="460.0" Width="53.333333333333336" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="192159" />
  </DataNode>
  <DataNode TextLabel="Ddx25" GraphId="c34" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Ddx25 | DEAD (Asp-Glu-Ala-Asp) box polypeptide ..." />
    <Graphics CenterX="1636.6666666666667" CenterY="1486.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="30959" />
  </DataNode>
  <DataNode TextLabel="Oasl2" GraphId="c38" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Oasl2 | 2â-5â oligoadenylate synthetase-like 2" />
    <Graphics CenterX="1773.3333333333333" CenterY="1446.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="23962" />
  </DataNode>
  <DataNode TextLabel="2810442I21Rik" GraphId="c3a" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="2810442I21Rik | RIKEN cDNA 2810442I21 gene" />
    <Graphics CenterX="216.66666666666666" CenterY="1690.0" Width="106.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="72735" />
  </DataNode>
  <DataNode TextLabel="3830425H19Rik" GraphId="c3b" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="RIKEN cDNA 3830425H19 gene" />
    <Graphics CenterX="370.0" CenterY="1150.0" Width="106.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="MGI" ID="MGI:1923985" />
  </DataNode>
  <DataNode TextLabel="1190005F20Rik" GraphId="c3c" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="1190005F20Rik | RIKEN cDNA 1190005F20 gene" />
    <Graphics CenterX="1483.3333333333333" CenterY="1246.6666666666667" Width="106.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="98685" />
  </DataNode>
  <DataNode TextLabel="8030431D03Rik" GraphId="c3d" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="RIKEN cDNA 8030431D03 gene" />
    <Graphics CenterX="370.0" CenterY="1710.0" Width="100.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="MGI" ID="MGI:1924422" />
  </DataNode>
  <DataNode TextLabel="Phf5a" GraphId="c3f" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Phf5a | PHD finger protein 5A" />
    <Graphics CenterX="700.0" CenterY="493.3333333333333" Width="66.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="68479" />
  </DataNode>
  <DataNode TextLabel="Csad" GraphId="c41" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Csad | cysteine sulfinic acid decarboxylase" />
    <Graphics CenterX="670.0" CenterY="1810.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="246277" />
  </DataNode>
  <DataNode TextLabel="4930506D01Rik" GraphId="c44" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="RIKEN cDNA 4930506D01 gene" />
    <Graphics CenterX="370.0" CenterY="1310.0" Width="106.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="MGI" ID="MGI:1922339" />
  </DataNode>
  <DataNode TextLabel="Pcbp1" GraphId="c46" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pcbp1 | poly(rC) binding protein 1" />
    <Graphics CenterX="1773.3333333333333" CenterY="1506.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="23983" />
  </DataNode>
  <DataNode TextLabel="Exosc8" GraphId="c49" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Exosc8 | exosome component 8" />
    <Graphics CenterX="1483.3333333333333" CenterY="1366.6666666666667" Width="106.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="69639" />
  </DataNode>
  <DataNode TextLabel="5730557B15Rik" GraphId="c4f" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="5730557B15Rik | RIKEN cDNA 5730557B15 gene" />
    <Graphics CenterX="370.0" CenterY="1590.0" Width="100.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="67434" />
  </DataNode>
  <DataNode TextLabel="Srpk2" GraphId="c51" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">PMID: 12773558</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Srpk2 | serine/arginine-rich protein specific k..." />
    <Graphics CenterX="1616.6666666666667" CenterY="666.6666666666666" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="20817" />
  </DataNode>
  <DataNode TextLabel="Prpf4" GraphId="c53" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Prpf4 | PRP4 pre-mRNA processing factor 4 homol..." />
    <Graphics CenterX="696.6666666666666" CenterY="663.3333333333334" Width="73.33333333333333" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="70052" />
  </DataNode>
  <DataNode TextLabel="Rpl8" GraphId="c55" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Rpl8 | ribosomal protein L8" />
    <Graphics CenterX="1906.6666666666667" CenterY="1263.3333333333333" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="26961" />
  </DataNode>
  <DataNode TextLabel="2610020N02Rik" GraphId="c57" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="2610020N02Rik | RIKEN cDNA 2610020N02 gene" />
    <Graphics CenterX="216.66666666666666" CenterY="1330.0" Width="106.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="353258" />
  </DataNode>
  <DataNode TextLabel="Rbm10" GraphId="c58" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Rbm10 | RNA binding motif protein 10" />
    <Graphics CenterX="953.3333333333334" CenterY="1706.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="236732" />
  </DataNode>
  <DataNode TextLabel="U5 snRNA" GraphId="c59" Type="Rna">
    <Comment Source="GenMAPP remarks">GenBank sequence: AB021173</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="U5 snRNA" />
    <Graphics CenterX="796.6666666666666" CenterY="623.3333333333334" Width="73.33333333333333" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Other" ID="AB021173" />
  </DataNode>
  <DataNode TextLabel="Rps27" GraphId="c61" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Rps27 | ribosomal protein S27" />
    <Graphics CenterX="1906.6666666666667" CenterY="1423.3333333333333" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="57294" />
  </DataNode>
  <DataNode TextLabel="Nufip1" GraphId="c62" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Nufip1 | nuclear fragile X mental retardation p..." />
    <Graphics CenterX="1773.3333333333333" CenterY="1306.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="27275" />
  </DataNode>
  <DataNode TextLabel="Imp4" GraphId="c69" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Imp4 | IMP4 U3 small nucleolar ribonucleoprot..." />
    <Graphics CenterX="1636.6666666666667" CenterY="1366.6666666666667" Width="100.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="27993" />
  </DataNode>
  <DataNode TextLabel="Lsm4" GraphId="c6a" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Lsm4 | LSM4 homolog U6 small nuclear RNA asso..." />
    <Graphics CenterX="1773.3333333333333" CenterY="1186.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="50783" />
  </DataNode>
  <DataNode TextLabel="Rbmxrt" GraphId="c70" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Rbmxrt | RNA binding motif protein X chromoso..." />
    <Graphics CenterX="323.3333333333333" CenterY="453.3333333333333" Width="69.33333333333333" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="19656" />
  </DataNode>
  <DataNode TextLabel="Aco1" GraphId="c72" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Aco1 | aconitase 1" />
    <Graphics CenterX="1483.3333333333333" CenterY="1806.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="11428" />
  </DataNode>
  <DataNode TextLabel="Wbscr1" GraphId="c73" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Wbscr1 | Williams-Beuren syndrome chromosome re..." />
    <Graphics CenterX="1183.3333333333333" CenterY="1206.6666666666667" Width="66.66460666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="22384" />
  </DataNode>
  <DataNode TextLabel="Hnrpa2b1" GraphId="c74" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Hnrpa2b1 | heterogeneous nuclear ribonucleoprot..." />
    <Graphics CenterX="323.3333333333333" CenterY="373.3333333333333" Width="69.33333333333333" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="53379" />
  </DataNode>
  <DataNode TextLabel="Rod1" GraphId="c7b" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Rod1 | ROD1 regulator of differentiation 1 (S. ..." />
    <Graphics CenterX="1066.6666666666667" CenterY="1306.6666666666667" Width="66.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="230257" />
  </DataNode>
  <DataNode TextLabel="C330027G06Rik" GraphId="c7d" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="C330027G06Rik | RIKEN cDNA C330027G06 gene" />
    <Graphics CenterX="670.0" CenterY="1390.0" Width="103.33333333333333" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="68280" />
  </DataNode>
  <DataNode TextLabel="Cstf2t" GraphId="c7f" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Cstf2t | cleavage stimulation factor 3â pre-R..." />
    <Graphics CenterX="1536.6666666666667" CenterY="153.33333333333334" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="83410" />
  </DataNode>
  <DataNode TextLabel="Eif4e3" GraphId="c81" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Eif4e3 | eukaryotic translation initiation fact..." />
    <Graphics CenterX="1483.3333333333333" CenterY="1266.6666666666667" Width="106.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="66892" />
  </DataNode>
  <DataNode TextLabel="1300006N24Rik" GraphId="c82" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="1300006N24Rik | RIKEN cDNA 1300006N24 gene" />
    <Graphics CenterX="70.0" CenterY="1350.0" Width="100.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="71766" />
  </DataNode>
  <DataNode TextLabel="Ppargc1b" GraphId="c84" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Ppargc1b | peroxisome proliferative activated ..." />
    <Graphics CenterX="953.3333333333334" CenterY="1446.6666666666667" Width="93.33333333333333" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="170826" />
  </DataNode>
  <DataNode TextLabel="Slc6a8" GraphId="c87" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Slc6a8 | solute carrier family 6 (neurotransmi..." />
    <Graphics CenterX="1066.6666666666667" CenterY="1586.6666666666667" Width="66.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="102857" />
  </DataNode>
  <DataNode TextLabel="AI642080" GraphId="c89" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="AI642080 | expressed sequence AI642080" />
    <Graphics CenterX="516.6666666666666" CenterY="1670.0" Width="63.333333333333336" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="103805" />
  </DataNode>
  <DataNode TextLabel="Tarbp2" GraphId="c8a" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Tarbp2 | TAR (HIV) RNA binding protein 2" />
    <Graphics CenterX="1906.6666666666667" CenterY="1783.3333333333333" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="21357" />
  </DataNode>
  <DataNode TextLabel="BC013481" GraphId="c8d" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="BC013481 | cDNA sequence BC013481" />
    <Graphics CenterX="670.0" CenterY="1250.0" Width="66.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="245945" />
  </DataNode>
  <DataNode TextLabel="D11Ertd730e" GraphId="c8e" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="D11Ertd730e | DNA segment Chr 11 ERATO Doi 7..." />
    <Graphics CenterX="2000.0" CenterY="663.3333333333334" Width="100.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="193116" />
  </DataNode>
  <DataNode TextLabel="Dhx16" GraphId="c90" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Dhx16 | DEAH (Asp-Glu-Ala-His) box polypeptide ..." />
    <Graphics CenterX="1816.6666666666667" CenterY="626.6666666666666" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="69192" />
  </DataNode>
  <DataNode TextLabel="Rpl12" GraphId="c91" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Rpl12 | ribosomal protein L12" />
    <Graphics CenterX="1773.3333333333333" CenterY="1783.3333333333333" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="269261" />
  </DataNode>
  <DataNode TextLabel="Rbm21" GraphId="c96" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Rbm21 | RNA binding motif protein 21" />
    <Graphics CenterX="216.66666666666666" CenterY="1530.0" Width="106.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="70044" />
  </DataNode>
  <DataNode TextLabel="Cirbp" GraphId="c9a" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Cirbp | cold inducible RNA binding protein" />
    <Graphics CenterX="670.0" CenterY="1750.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="12696" />
  </DataNode>
  <DataNode TextLabel="Rad52b" GraphId="c9b" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Rad52b | RAD52 homolog B (S. cerevisiae)" />
    <Graphics CenterX="70.0" CenterY="1770.0" Width="100.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="66599" />
  </DataNode>
  <DataNode TextLabel="C230097K14Rik" GraphId="ca0" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="RIKEN cDNA C230097K14 gene" />
    <Graphics CenterX="670.0" CenterY="1350.0" Width="103.33333333333333" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="MGI" ID="MGI:2441901" />
  </DataNode>
  <DataNode TextLabel="Pabpc4" GraphId="ca1" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pabpc4 | poly A binding protein cytoplasmic 4..." />
    <Graphics CenterX="953.3333333333334" CenterY="1506.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="230721" />
  </DataNode>
  <DataNode TextLabel="4922503N01Rik" GraphId="ca3" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="4922503N01Rik | RIKEN cDNA 4922503N01 gene" />
    <Graphics CenterX="370.0" CenterY="1250.0" Width="106.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="230603" />
  </DataNode>
  <DataNode TextLabel="Elavl4" GraphId="ca4" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Elavl4 | ELAV (embryonic lethal abnormal visi..." />
    <Graphics CenterX="810.0" CenterY="1446.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="15572" />
  </DataNode>
  <DataNode TextLabel="Brca1" GraphId="ca5" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Brca1 | breast cancer 1" />
    <Graphics CenterX="1636.6666666666667" CenterY="1306.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="12189" />
  </DataNode>
  <DataNode TextLabel="Ttc14" GraphId="ca6" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Ttc14 | tetratricopeptide repeat domain 14" />
    <Graphics CenterX="1483.3333333333333" CenterY="1546.6666666666667" Width="106.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="67120" />
  </DataNode>
  <DataNode TextLabel="Rpl11" GraphId="ca7" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Rpl11 | ribosomal protein L11" />
    <Graphics CenterX="1483.3333333333333" CenterY="1346.6666666666667" Width="106.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="67025" />
  </DataNode>
  <DataNode TextLabel="AI255840" GraphId="ca9" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="expressed sequence AI255840" />
    <Graphics CenterX="516.6666666666666" CenterY="1450.0" Width="63.333333333333336" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="MGI" ID="MGI:2146810" />
  </DataNode>
  <DataNode TextLabel="D3Jfr1" GraphId="cab" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="D3Jfr1 | DNA segment Chr 3 MJeffers 1" />
    <Graphics CenterX="1636.6666666666667" CenterY="1386.6666666666667" Width="100.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="229663" />
  </DataNode>
  <DataNode TextLabel="AU045931" GraphId="cb4" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="expressed sequence AU045931" />
    <Graphics CenterX="516.6666666666666" CenterY="1810.0" Width="66.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="MGI" ID="MGI:2141597" />
  </DataNode>
  <DataNode TextLabel="Trim21" GraphId="cb5" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Trim21 | tripartite motif protein 21" />
    <Graphics CenterX="2030.0" CenterY="1166.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="20821" />
  </DataNode>
  <DataNode TextLabel="Raly" GraphId="cb7" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Raly | hnRNP-associated with lethal yellow" />
    <Graphics CenterX="810.0" CenterY="1706.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="19383" />
  </DataNode>
  <DataNode TextLabel="Eif4g2" GraphId="cb9" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Eif4g2 | eukaryotic translation initiation fac..." />
    <Graphics CenterX="810.0" CenterY="1526.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="13690" />
  </DataNode>
  <DataNode TextLabel="5330419I02Rik" GraphId="cbc" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="RIKEN cDNA 5330419I02 gene" />
    <Graphics CenterX="370.0" CenterY="1510.0" Width="95.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="MGI" ID="MGI:2442152" />
  </DataNode>
  <DataNode TextLabel="MGI:2661424" GraphId="cbf" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">PMID: 11684676</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="MGI:2661424 | serine-arginine repressor protein..." />
    <Graphics CenterX="1820.0" CenterY="946.6666666666666" Width="66.73333333333333" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="272009" />
  </DataNode>
  <DataNode TextLabel="D15Ertd119e" GraphId="cc1" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="DNA segment, Chr 15, ERATO Doi 119, expressed" />
    <Graphics CenterX="810.0" CenterY="1326.6666666666667" Width="86.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="MGI" ID="MGI:1261777" />
  </DataNode>
  <DataNode TextLabel="Synj2" GraphId="cc5" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Synj2 | synaptojanin 2" />
    <Graphics CenterX="1066.6666666666667" CenterY="1626.6666666666667" Width="66.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="20975" />
  </DataNode>
  <DataNode TextLabel="Hnrpl" GraphId="cc8" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Hnrpl | heterogeneous nuclear ribonucleoprotein..." />
    <Graphics CenterX="423.3333333333333" CenterY="393.3333333333333" Width="66.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="15388" />
  </DataNode>
  <DataNode TextLabel="Msi2h" GraphId="ccc" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Msi2h | Musashi homolog 2 (Drosophila)" />
    <Graphics CenterX="953.3333333333334" CenterY="1246.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="76626" />
  </DataNode>
  <DataNode TextLabel="AL022933" GraphId="ccd" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="expressed sequence AL022933" />
    <Graphics CenterX="516.6666666666666" CenterY="1730.0" Width="66.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="MGI" ID="MGI:2141534" />
  </DataNode>
  <DataNode TextLabel="Zfp346" GraphId="cce" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Zfp346 | zinc finger protein 346" />
    <Graphics CenterX="2030.0" CenterY="1246.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="26919" />
  </DataNode>
  <DataNode TextLabel="Nol8" GraphId="ccf" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Nol8 | nucleolar protein 8" />
    <Graphics CenterX="370.0" CenterY="1230.0" Width="106.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="70930" />
  </DataNode>
  <DataNode TextLabel="Eif3s9" GraphId="cd3" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Eif3s9 | eukaryotic translation initiation fac..." />
    <Graphics CenterX="810.0" CenterY="1506.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="27979" />
  </DataNode>
  <DataNode TextLabel="Polr2g" GraphId="cd6" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Polr2g | polymerase (RNA) II (DNA directed) pol..." />
    <Graphics CenterX="1773.3333333333333" CenterY="1586.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="67710" />
  </DataNode>
  <DataNode TextLabel="Rbm13" GraphId="cd9" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Rbm13 | RNA binding motif protein 13" />
    <Graphics CenterX="216.66666666666666" CenterY="1210.0" Width="100.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="67920" />
  </DataNode>
  <DataNode TextLabel="Ssb" GraphId="cda" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Ssb | Sjogren syndrome antigen B" />
    <Graphics CenterX="1066.6666666666667" CenterY="1526.6666666666667" Width="66.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="20823" />
  </DataNode>
  <DataNode TextLabel="Hnrpa0" GraphId="cdf" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Hnrpa0 | heterogeneous nuclear ribonucleoprotei..." />
    <Graphics CenterX="216.66666666666666" CenterY="1750.0" Width="106.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="77134" />
  </DataNode>
  <DataNode TextLabel="AI255219" GraphId="ce0" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="expressed sequence AI255219" />
    <Graphics CenterX="516.6666666666666" CenterY="1370.0" Width="63.333333333333336" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="MGI" ID="MGI:2143545" />
  </DataNode>
  <DataNode TextLabel="Hrmt1l2" GraphId="ce1" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Hrmt1l2 | heterogeneous nuclear ribonucleoprote..." />
    <Graphics CenterX="1816.6666666666667" CenterY="770.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="15469" />
  </DataNode>
  <DataNode TextLabel="Lgtn" GraphId="ce2" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Lgtn | ligatin" />
    <Graphics CenterX="1773.3333333333333" CenterY="1166.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="16865" />
  </DataNode>
  <DataNode TextLabel="Traf6" GraphId="ce3" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Traf6 | Tnf receptor-associated factor 6" />
    <Graphics CenterX="1066.6666666666667" CenterY="1746.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="22034" />
  </DataNode>
  <DataNode TextLabel="D8Ertd233e" GraphId="ce5" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="D8Ertd233e | DNA segment Chr 8 ERATO Doi 233..." />
    <Graphics CenterX="810.0" CenterY="1366.6666666666667" Width="80.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="52202" />
  </DataNode>
  <DataNode TextLabel="Eif4e2" GraphId="ce6" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Eif4e2 | eukaryotic translation initiation fact..." />
    <Graphics CenterX="1636.6666666666667" CenterY="1726.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="26987" />
  </DataNode>
  <DataNode TextLabel="Rpl32" GraphId="ce8" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Rpl32 | ribosomal protein L32" />
    <Graphics CenterX="1906.6666666666667" CenterY="1183.3333333333333" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="19951" />
  </DataNode>
  <DataNode TextLabel="D5Ertd700e" GraphId="ceb" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="D5Ertd700e | DNA segment Chr 5 ERATO Doi 700..." />
    <Graphics CenterX="810.0" CenterY="1346.6666666666667" Width="80.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="52387" />
  </DataNode>
  <DataNode TextLabel="Cova1" GraphId="cee" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Cova1 | cytosolic ovarian carcinoma antigen 1" />
    <Graphics CenterX="810.0" CenterY="1226.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="209224" />
  </DataNode>
  <DataNode TextLabel="Rps20" GraphId="cef" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Rps20 | ribosomal protein S20" />
    <Graphics CenterX="1906.6666666666667" CenterY="1363.3333333333333" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="67427" />
  </DataNode>
  <DataNode TextLabel="Sf3a1" GraphId="cf0" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Sf3a1 | splicing factor 3a subunit 1" />
    <Graphics CenterX="596.6666666666666" CenterY="456.6666666666667" Width="66.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="67465" />
  </DataNode>
  <DataNode TextLabel="3200001K10Rik" GraphId="cf1" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="3200001K10Rik | RIKEN cDNA 3200001K10 gene" />
    <Graphics CenterX="216.66666666666666" CenterY="1810.0" Width="106.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="381626" />
  </DataNode>
  <DataNode TextLabel="Rbms3" GraphId="cf3" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Rbms3 | RNA binding motif single stranded int..." />
    <Graphics CenterX="370.0" CenterY="1670.0" Width="100.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="207181" />
  </DataNode>
  <DataNode TextLabel="AI255207" GraphId="cf6" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="AI255207 | expressed sequence AI255207" />
    <Graphics CenterX="516.6666666666666" CenterY="1310.0" Width="63.333333333333336" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="102459" />
  </DataNode>
  <DataNode TextLabel="2810036M01Rik" GraphId="cfa" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="RIKEN cDNA 2810036M01 gene" />
    <Graphics CenterX="216.66666666666666" CenterY="1610.0" Width="106.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="MGI" ID="MGI:1919914" />
  </DataNode>
  <DataNode TextLabel="Eif4e" GraphId="cfc" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Eif4e | eukaryotic translation initiation facto..." />
    <Graphics CenterX="1636.6666666666667" CenterY="1706.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="13684" />
  </DataNode>
  <DataNode TextLabel="Rnpep" GraphId="cfe" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Rnpep | arginyl aminopeptidase (aminopeptidase ..." />
    <Graphics CenterX="1066.6666666666667" CenterY="1346.6666666666667" Width="66.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="215615" />
  </DataNode>
  <DataNode TextLabel="2610015J01Rik" GraphId="d04" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="RIKEN cDNA 2610015J01 gene" />
    <Graphics CenterX="216.66666666666666" CenterY="1290.0" Width="100.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="MGI" ID="MGI:1917471" />
  </DataNode>
  <DataNode TextLabel="AI255183" GraphId="d0c" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="EST AI255183" />
    <Graphics CenterX="516.6666666666666" CenterY="1290.0" Width="63.333333333333336" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="MGI" ID="MGI:1353607" />
  </DataNode>
  <DataNode TextLabel="Bat1a" GraphId="d0e" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Bat1a | HLA-B-associated transcript 1A" />
    <Graphics CenterX="1636.6666666666667" CenterY="1266.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="53817" />
  </DataNode>
  <DataNode TextLabel="AA589495" GraphId="d11" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="expressed sequence AA589495" />
    <Graphics CenterX="516.6666666666666" CenterY="1210.0" Width="66.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="MGI" ID="MGI:2143495" />
  </DataNode>
  <DataNode TextLabel="Igf2bp3" GraphId="d15" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Igf2bp3 | insulin-like growth factor 2 bindin..." />
    <Graphics CenterX="810.0" CenterY="1766.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="140488" />
  </DataNode>
  <DataNode TextLabel="Rnu11" GraphId="d19" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Rnu11 | U11 small nuclear RNA" />
    <Graphics CenterX="1066.6666666666667" CenterY="1406.6666666666667" Width="66.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="353373" />
  </DataNode>
  <DataNode TextLabel="Srrm1" GraphId="d1a" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Srrm1" />
    <Graphics CenterX="1616.6666666666667" CenterY="926.6666666666666" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="51796" />
  </DataNode>
  <DataNode TextLabel="Ddx20" GraphId="d1c" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Ddx20 | DEAD (Asp-Glu-Ala-Asp) box polypeptide ..." />
    <Graphics CenterX="1816.6666666666667" CenterY="566.6666666666666" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="53975" />
  </DataNode>
  <DataNode TextLabel="Pcbp2" GraphId="d1d" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pcbp2 | poly(rC) binding protein 2" />
    <Graphics CenterX="1816.6666666666667" CenterY="810.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="18521" />
  </DataNode>
  <DataNode TextLabel="AI447568" GraphId="d1e" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="expressed sequence AI447568" />
    <Graphics CenterX="516.6666666666666" CenterY="1550.0" Width="63.333333333333336" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="MGI" ID="MGI:2139707" />
  </DataNode>
  <DataNode TextLabel="Mbnl1" GraphId="d1f" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Mbnl1 | muscleblind-like 1 (Drosophila)" />
    <Graphics CenterX="1773.3333333333333" CenterY="1206.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="56758" />
  </DataNode>
  <DataNode TextLabel="AI194270" GraphId="d21" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="AI194270 | expressed sequence AI194270" />
    <Graphics CenterX="516.6666666666666" CenterY="1250.0" Width="63.333333333333336" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="98871" />
  </DataNode>
  <DataNode TextLabel="2810028N01Rik" GraphId="d27" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="2810028N01Rik | RIKEN cDNA 2810028N01 gene" />
    <Graphics CenterX="1483.3333333333333" CenterY="1606.6666666666667" Width="106.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="72662" />
  </DataNode>
  <DataNode TextLabel="Rnu108" GraphId="d33" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Rnu108 | RNA U108 small nucleolar" />
    <Graphics CenterX="1066.6666666666667" CenterY="1386.6666666666667" Width="66.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="104433" />
  </DataNode>
  <DataNode TextLabel="Lsm2" GraphId="d3a" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Lsm2 | LSM2 homolog U6 small nuclear RNA asso..." />
    <Graphics CenterX="696.6666666666666" CenterY="683.3333333333334" Width="73.33333333333333" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="27756" />
  </DataNode>
  <DataNode TextLabel="Tnrc4" GraphId="d3c" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Tnrc4 | trinucleotide repeat containing 4" />
    <Graphics CenterX="1066.6666666666667" CenterY="1786.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="78784" />
  </DataNode>
  <DataNode TextLabel="Acin1" GraphId="d3f" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Acin1 | apoptotic chromatin condensation induce..." />
    <Graphics CenterX="670.0" CenterY="1650.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="56215" />
  </DataNode>
  <DataNode TextLabel="Nxf1" GraphId="d43" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Nxf1 | nuclear RNA export factor 1 homolog (S. ..." />
    <Graphics CenterX="2000.0" CenterY="943.3333333333334" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="53319" />
  </DataNode>
  <DataNode TextLabel="2600016C11Rik" GraphId="d45" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="RIKEN cDNA 2600016C11 gene" />
    <Graphics CenterX="216.66666666666666" CenterY="1230.0" Width="100.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="MGI" ID="MGI:1919317" />
  </DataNode>
  <DataNode TextLabel="Prpf8" GraphId="d4b" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Prpf8 | pre-mRNA processing factor 8" />
    <Graphics CenterX="906.6666666666666" CenterY="683.3333333333334" Width="73.33333333333333" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="192159" />
  </DataNode>
  <DataNode TextLabel="AI504630" GraphId="d4e" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="expressed sequence AI504630" />
    <Graphics CenterX="516.6666666666666" CenterY="1650.0" Width="63.333333333333336" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="MGI" ID="MGI:2147572" />
  </DataNode>
  <DataNode TextLabel="Oas3" GraphId="d54" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Oas3 | 2â-5â oligoadenylate synthetase 3" />
    <Graphics CenterX="1773.3333333333333" CenterY="1426.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="246727" />
  </DataNode>
  <DataNode TextLabel="Grsf1" GraphId="d55" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Grsf1 | G-rich RNA sequence binding factor 1" />
    <Graphics CenterX="810.0" CenterY="1626.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="231413" />
  </DataNode>
  <DataNode TextLabel="Lsm7" GraphId="d56" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Lsm7 | LSM7 homolog U6 small nuclear RNA asso..." />
    <Graphics CenterX="2000.0" CenterY="863.3333333333334" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="66094" />
  </DataNode>
  <DataNode TextLabel="Rps14" GraphId="d57" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Rps14 | ribosomal protein S14" />
    <Graphics CenterX="1906.6666666666667" CenterY="1343.3333333333333" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="20044" />
  </DataNode>
  <DataNode TextLabel="Rbm28" GraphId="d5c" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Rbm28 | RNA binding motif protein 28" />
    <Graphics CenterX="216.66666666666666" CenterY="1710.0" Width="106.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="68272" />
  </DataNode>
  <DataNode TextLabel="C80672" GraphId="d5f" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="expressed sequence C80672" />
    <Graphics CenterX="670.0" CenterY="1450.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="MGI" ID="MGI:2143933" />
  </DataNode>
  <DataNode TextLabel="AI255750" GraphId="d61" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="expressed sequence AI255750" />
    <Graphics CenterX="516.6666666666666" CenterY="1430.0" Width="63.333333333333336" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="MGI" ID="MGI:2146392" />
  </DataNode>
  <DataNode TextLabel="C79783" GraphId="d63" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="expressed sequence C79783" />
    <Graphics CenterX="670.0" CenterY="1430.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="MGI" ID="MGI:2142336" />
  </DataNode>
  <DataNode TextLabel="U2af1" GraphId="d66" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="U2af1 | U2 small nuclear ribonucleoprotein auxi..." />
    <Graphics CenterX="820.0" CenterY="183.33333333333334" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="108121" />
  </DataNode>
  <DataNode TextLabel="Clk3" GraphId="d68" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Clk3 | CDC-like kinase 3" />
    <Graphics CenterX="1616.6666666666667" CenterY="586.6666666666666" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="102414" />
  </DataNode>
  <DataNode TextLabel="5031411E02Rik" GraphId="d6b" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="RIKEN cDNA 5031411E02 gene" />
    <Graphics CenterX="370.0" CenterY="1490.0" Width="100.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="MGI" ID="MGI:2445088" />
  </DataNode>
  <DataNode TextLabel="Rbpms" GraphId="d6d" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Rbpms | RNA binding protein gene with multiple ..." />
    <Graphics CenterX="1066.6666666666667" CenterY="1226.6666666666667" Width="66.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="19663" />
  </DataNode>
  <DataNode TextLabel="Prpf3" GraphId="d6e" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Prpf3 | PRP3 pre-mRNA processing factor 3 homol..." />
    <Graphics CenterX="2000.0" CenterY="803.3333333333334" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="70767" />
  </DataNode>
  <DataNode TextLabel="Tardbp" GraphId="d70" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Tardbp | TAR DNA binding protein" />
    <Graphics CenterX="1066.6666666666667" CenterY="1666.6666666666667" Width="66.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="230908" />
  </DataNode>
  <DataNode TextLabel="Rps24" GraphId="d73" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Rps24 | ribosomal protein S24" />
    <Graphics CenterX="1906.6666666666667" CenterY="1403.3333333333333" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="20088" />
  </DataNode>
  <DataNode TextLabel="U2af2" GraphId="d75" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="U2af2 | U2 small nuclear ribonucleoprotein auxi..." />
    <Graphics CenterX="820.0" CenterY="203.33333333333334" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="22185" />
  </DataNode>
  <DataNode TextLabel="Clk4" GraphId="d78" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Clk4 | CDC like kinase 4" />
    <Graphics CenterX="1616.6666666666667" CenterY="606.6666666666666" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="12750" />
  </DataNode>
  <DataNode TextLabel="Dhx38" GraphId="d79" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Dhx38 | DEAH (Asp-Glu-Ala-His) box polypeptide ..." />
    <Graphics CenterX="933.3333333333334" CenterY="460.0" Width="48.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="64340" />
  </DataNode>
  <DataNode TextLabel="1810036A22Rik" GraphId="d7a" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="RIKEN cDNA 1810036A22 gene" />
    <Graphics CenterX="70.0" CenterY="1590.0" Width="100.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="MGI" ID="MGI:1916407" />
  </DataNode>
  <DataNode TextLabel="AI844780" GraphId="d7e" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="expressed sequence AI844780" />
    <Graphics CenterX="516.6666666666666" CenterY="1710.0" Width="63.333333333333336" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="MGI" ID="MGI:2141491" />
  </DataNode>
  <DataNode TextLabel="Elavl3" GraphId="d82" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Elavl3 | ELAV (embryonic lethal abnormal visi..." />
    <Graphics CenterX="810.0" CenterY="1426.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="15571" />
  </DataNode>
  <DataNode TextLabel="AU023006" GraphId="d84" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="AU023006 | expressed sequence AU023006" />
    <Graphics CenterX="516.6666666666666" CenterY="1790.0" Width="66.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="102683" />
  </DataNode>
  <DataNode TextLabel="Sfrs3" GraphId="d88" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Sfrs3" />
    <Graphics CenterX="773.3333333333334" CenterY="290.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="20383" />
  </DataNode>
  <DataNode TextLabel="Rbm15b" GraphId="d8b" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Rbm15b | RNA binding motif protein 15B" />
    <Graphics CenterX="70.0" CenterY="1550.0" Width="100.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="109095" />
  </DataNode>
  <DataNode TextLabel="Akap1" GraphId="d8c" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Akap1 | A kinase (PRKA) anchor protein 1" />
    <Graphics CenterX="1636.6666666666667" CenterY="1206.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="11640" />
  </DataNode>
  <DataNode TextLabel="5730453I16Rik" GraphId="d90" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="5730453I16Rik | RIKEN cDNA 5730453I16 gene" />
    <Graphics CenterX="370.0" CenterY="1530.0" Width="95.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="269061" />
  </DataNode>
  <DataNode TextLabel="Sfrs11" GraphId="d93" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Sfrs11 | splicing factor arginine/serine-rich..." />
    <Graphics CenterX="216.66666666666666" CenterY="1310.0" Width="100.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="69207" />
  </DataNode>
  <DataNode TextLabel="Nhp2l1" GraphId="d96" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Nhp2l1 | NHP2 non-histone chromosome protein 2-..." />
    <Graphics CenterX="1906.6666666666667" CenterY="1743.3333333333333" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="20826" />
  </DataNode>
  <DataNode TextLabel="Rbm6" GraphId="d98" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Rbm6 | RNA binding motif protein 6" />
    <Graphics CenterX="953.3333333333334" CenterY="1646.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="19654" />
  </DataNode>
  <DataNode TextLabel="Tert" GraphId="d99" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Tert | telomerase reverse transcriptase" />
    <Graphics CenterX="2030.0" CenterY="1146.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="21752" />
  </DataNode>
  <DataNode TextLabel="Sf3a3" GraphId="d9b" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Sf3a3 | splicing factor 3a subunit 3" />
    <Graphics CenterX="596.6666666666666" CenterY="496.6666666666667" Width="66.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="75062" />
  </DataNode>
  <DataNode TextLabel="4930562C03Rik" GraphId="d9c" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="4930562C03Rik | RIKEN cDNA 4930562C03 gene" />
    <Graphics CenterX="370.0" CenterY="1350.0" Width="106.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="67667" />
  </DataNode>
  <DataNode TextLabel="2610317D23Rik" GraphId="d9d" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="2610317D23Rik | RIKEN cDNA 2610317D23 gene" />
    <Graphics CenterX="2000.0" CenterY="643.3333333333334" Width="100.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="54614" />
  </DataNode>
  <DataNode TextLabel="Nhp2l1" GraphId="d9e" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Nhp2l1 | NHP2 non-histone chromosome protein 2-..." />
    <Graphics CenterX="596.6666666666666" CenterY="646.6666666666666" Width="73.33333333333333" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="20826" />
  </DataNode>
  <DataNode TextLabel="Hnrpf" GraphId="da0" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Hnrpf | heterogeneous nuclear ribonucleoprotein..." />
    <Graphics CenterX="370.0" CenterY="1190.0" Width="106.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="98758" />
  </DataNode>
  <DataNode TextLabel="Dnd1" GraphId="da3" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Dnd1 | dead end homolog 1 (zebrafish)" />
    <Graphics CenterX="670.0" CenterY="1270.0" Width="66.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="213236" />
  </DataNode>
  <DataNode TextLabel="Rbm8a" GraphId="daf" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Rbm8a | RNA binding motif protein 8a" />
    <Graphics CenterX="953.3333333333334" CenterY="1666.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="60365" />
  </DataNode>
  <DataNode TextLabel="Hnrpu" GraphId="db0" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Hnrpu | heterogeneous nuclear ribonucleoprotein..." />
    <Graphics CenterX="423.3333333333333" CenterY="453.3333333333333" Width="66.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="51810" />
  </DataNode>
  <DataNode TextLabel="Ggcx" GraphId="db1" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Ggcx | gamma-glutamyl carboxylase" />
    <Graphics CenterX="810.0" CenterY="1606.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="56316" />
  </DataNode>
  <DataNode TextLabel="Auh" GraphId="db2" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Auh | AU RNA binding protein/enoyl-coenzyme A h..." />
    <Graphics CenterX="1636.6666666666667" CenterY="1226.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="11992" />
  </DataNode>
  <DataNode TextLabel="Hnrph2" GraphId="db4" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Hnrph2 | heterogeneous nuclear ribonucleoprotei..." />
    <Graphics CenterX="423.3333333333333" CenterY="353.3333333333333" Width="66.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="56258" />
  </DataNode>
  <DataNode TextLabel="Rbms2" GraphId="db5" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Rbms2 | RNA binding motif single stranded int..." />
    <Graphics CenterX="1066.6666666666667" CenterY="1146.6666666666667" Width="66.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="56516" />
  </DataNode>
  <DataNode TextLabel="Pabpc2" GraphId="db9" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pabpc2 | poly A binding protein cytoplasmic 2..." />
    <Graphics CenterX="953.3333333333334" CenterY="1486.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="18459" />
  </DataNode>
  <DataNode TextLabel="Sf3a2" GraphId="dba" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Sf3a2 | splicing factor 3a subunit 2" />
    <Graphics CenterX="596.6666666666666" CenterY="476.6666666666667" Width="66.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="20222" />
  </DataNode>
  <DataNode TextLabel="Rnu1a1" GraphId="dc3" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Rnu1a1 | U1a1 small nuclear RNA" />
    <Graphics CenterX="1066.6666666666667" CenterY="1426.6666666666667" Width="66.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="19842" />
  </DataNode>
  <DataNode TextLabel="Spop" GraphId="dc4" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Spop | speckle-type POZ protein" />
    <Graphics CenterX="2000.0" CenterY="783.3333333333334" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="20747" />
  </DataNode>
  <DataNode TextLabel="Nxf7" GraphId="dc8" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Nxf7 | nuclear RNA export factor 7" />
    <Graphics CenterX="1773.3333333333333" CenterY="1326.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="170722" />
  </DataNode>
  <DataNode TextLabel="Uhmk1" GraphId="dc9" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Uhmk1 | U2AF homology motif (UHM) kinase 1" />
    <Graphics CenterX="810.0" CenterY="1786.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="16589" />
  </DataNode>
  <DataNode TextLabel="Cpsf3" GraphId="dcb" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Cpsf3 | cleavage and polyadenylation specificit..." />
    <Graphics CenterX="1303.3333333333333" CenterY="173.33333333333334" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="54451" />
  </DataNode>
  <DataNode TextLabel="Nsap1l-pending" GraphId="dcf" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="NS1-associated protein 1-like" />
    <Graphics CenterX="953.3333333333334" CenterY="1306.6666666666667" Width="106.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="MGI" ID="MGI:1930916" />
  </DataNode>
  <DataNode TextLabel="Slc25a4" GraphId="dd0" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Slc25a4 | solute carrier family 25 (mitochondr..." />
    <Graphics CenterX="1066.6666666666667" CenterY="1566.6666666666667" Width="66.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="11739" />
  </DataNode>
  <DataNode TextLabel="Ptbp1" GraphId="dd1" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Ptbp1 | polypyrimidine tract binding protein 1" />
    <Graphics CenterX="1060.0" CenterY="500.0" Width="53.333333333333336" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="19205" />
  </DataNode>
  <DataNode TextLabel="Srp9" GraphId="dd9" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Srp9 | signal recognition particle 9" />
    <Graphics CenterX="1906.6666666666667" CenterY="1703.3333333333333" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="27058" />
  </DataNode>
  <DataNode TextLabel="Wbp4" GraphId="ddb" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Wbp4 | WW domain binding protein 4" />
    <Graphics CenterX="2030.0" CenterY="1206.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="22380" />
  </DataNode>
  <DataNode TextLabel="Fxr1h" GraphId="ddc" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Fxr1h | fragile X mental retardation gene 1 a..." />
    <Graphics CenterX="1636.6666666666667" CenterY="1786.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="14359" />
  </DataNode>
  <DataNode TextLabel="Snrpd2" GraphId="ddd" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Snrpd2 | small nuclear ribonucleoprotein D2" />
    <Graphics CenterX="576.6666666666666" CenterY="306.6666666666667" Width="73.33333333333333" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="107686" />
  </DataNode>
  <DataNode TextLabel="Oas1g" GraphId="dec" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Oas1g | 2â-5â oligoadenylate synthetase 1G" />
    <Graphics CenterX="1773.3333333333333" CenterY="1386.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="23960" />
  </DataNode>
  <DataNode TextLabel="0710005M24Rik" GraphId="dee" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="0710005M24Rik | RIKEN cDNA 0710005M24 gene" />
    <Graphics CenterX="70.0" CenterY="1210.0" Width="100.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="76897" />
  </DataNode>
  <DataNode TextLabel="Tnrc6c" GraphId="def" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Tnrc6c | trinucleotide repeat containing 6C" />
    <Graphics CenterX="370.0" CenterY="1810.0" Width="100.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="217351" />
  </DataNode>
  <DataNode TextLabel="Rbm7" GraphId="df0" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Rbm7 | RNA binding motif protein 7" />
    <Graphics CenterX="70.0" CenterY="1370.0" Width="100.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="67010" />
  </DataNode>
  <DataNode TextLabel="Rbmx" GraphId="df1" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Rbmx | RNA binding motif protein X chromosome..." />
    <Graphics CenterX="1066.6666666666667" CenterY="1166.6666666666667" Width="66.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="19655" />
  </DataNode>
  <DataNode TextLabel="Rnpc2" GraphId="df2" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Rnpc2 | RNA-binding region (RNP1 RRM) contain..." />
    <Graphics CenterX="2000.0" CenterY="723.3333333333334" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="170791" />
  </DataNode>
  <DataNode TextLabel="Rbm22" GraphId="df4" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Rbm22 | RNA binding motif protein 22" />
    <Graphics CenterX="370.0" CenterY="1730.0" Width="100.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="66810" />
  </DataNode>
  <DataNode TextLabel="Mrpl23" GraphId="df9" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Mrpl23 | mitochondrial ribosomal protein L23" />
    <Graphics CenterX="1773.3333333333333" CenterY="1266.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="19935" />
  </DataNode>
  <DataNode TextLabel="Rbm31y" GraphId="dff" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Rbm31y | RNA binding motif 31 Y-linked" />
    <Graphics CenterX="370.0" CenterY="1470.0" Width="100.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="74484" />
  </DataNode>
  <DataNode TextLabel="Sf3b1" GraphId="e01" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Sf3b1 | splicing factor 3b subunit 1" />
    <Graphics CenterX="806.6666666666666" CenterY="426.6666666666667" Width="66.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="81898" />
  </DataNode>
  <DataNode TextLabel="1700025B16Rik" GraphId="e03" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="1700025B16Rik | RIKEN cDNA 1700025B16 gene" />
    <Graphics CenterX="70.0" CenterY="1490.0" Width="100.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="69408" />
  </DataNode>
  <DataNode TextLabel="Afg3l1" GraphId="e04" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Afg3l1 | AFG3(ATPase family gene 3)-like 1 (yea..." />
    <Graphics CenterX="670.0" CenterY="1630.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="114896" />
  </DataNode>
  <DataNode TextLabel="Cnot4" GraphId="e08" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Cnot4 | CCR4-NOT transcription complex subuni..." />
    <Graphics CenterX="670.0" CenterY="1710.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="53621" />
  </DataNode>
  <DataNode TextLabel="2410104I19Rik" GraphId="e0b" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="2410104I19Rik | RIKEN cDNA 2410104I19 gene" />
    <Graphics CenterX="216.66666666666666" CenterY="1150.0" Width="100.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="67959" />
  </DataNode>
  <DataNode TextLabel="0610033I05Rik" GraphId="e0e" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="0610033I05Rik | RIKEN cDNA 0610033I05 gene" />
    <Graphics CenterX="70.0" CenterY="1190.0" Width="100.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="71684" />
  </DataNode>
  <DataNode TextLabel="Pcolce" GraphId="e10" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pcolce | procollagen C-proteinase enhancer prot..." />
    <Graphics CenterX="953.3333333333334" CenterY="1566.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="18542" />
  </DataNode>
  <DataNode TextLabel="A130095G20Rik" GraphId="e11" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="RIKEN cDNA A130095G20 gene" />
    <Graphics CenterX="516.6666666666666" CenterY="1150.0" Width="103.33333333333333" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="MGI" ID="MGI:2144767" />
  </DataNode>
  <DataNode TextLabel="Cpsf2" GraphId="e14" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Cpsf2 | cleavage and polyadenylation specific f..." />
    <Graphics CenterX="1303.3333333333333" CenterY="153.33333333333334" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="51786" />
  </DataNode>
  <DataNode TextLabel="Elavl2" GraphId="e17" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Elavl2 | ELAV (embryonic lethal abnormal visi..." />
    <Graphics CenterX="810.0" CenterY="1406.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="15569" />
  </DataNode>
  <DataNode TextLabel="Rps4x" GraphId="e18" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Rps4x | ribosomal protein S4 X-linked" />
    <Graphics CenterX="1906.6666666666667" CenterY="1483.3333333333333" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="20102" />
  </DataNode>
  <DataNode TextLabel="Sf3b4" GraphId="e23" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Sf3b4 | splicing factor 3b subunit 4" />
    <Graphics CenterX="806.6666666666666" CenterY="486.6666666666667" Width="66.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="107701" />
  </DataNode>
  <DataNode TextLabel="Safb2" GraphId="e24" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Safb2 | scaffold attachment factor B2" />
    <Graphics CenterX="516.6666666666666" CenterY="1270.0" Width="63.333333333333336" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="224902" />
  </DataNode>
  <DataNode TextLabel="Rbed1" GraphId="e26" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Rbed1 | RNA binding motif and ELMO domain 1" />
    <Graphics CenterX="670.0" CenterY="1370.0" Width="103.33333333333333" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="232089" />
  </DataNode>
  <DataNode TextLabel="Eif4g3" GraphId="e27" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Eif4g3 | eukaryotic translation initiation fac..." />
    <Graphics CenterX="1483.3333333333333" CenterY="1286.6666666666667" Width="106.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="230861" />
  </DataNode>
  <DataNode TextLabel="Rps9" GraphId="e2a" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Rps9 | ribosomal protein S9" />
    <Graphics CenterX="1483.3333333333333" CenterY="1646.6666666666667" Width="106.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="76846" />
  </DataNode>
  <DataNode TextLabel="Prpf18" GraphId="e2e" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Prpf18 | PRP18 pre-mRNA processing factor 18 ho..." />
    <Graphics CenterX="2000.0" CenterY="603.3333333333334" Width="101.33333333333333" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="67229" />
  </DataNode>
  <DataNode TextLabel="Cpsf1" GraphId="e2f" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Cpsf1 | cleavage and polyadenylation specific f..." />
    <Graphics CenterX="1303.3333333333333" CenterY="133.33333333333334" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="94230" />
  </DataNode>
  <DataNode TextLabel="Scye1" GraphId="e30" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Scye1 | small inducible cytokine subfamily E ..." />
    <Graphics CenterX="1906.6666666666667" CenterY="1583.3333333333333" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="13722" />
  </DataNode>
  <DataNode TextLabel="Sfrs5" GraphId="e31" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Sfrs5" />
    <Graphics CenterX="773.3333333333334" CenterY="310.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="20384" />
  </DataNode>
  <DataNode TextLabel="Rnaset2" GraphId="e32" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Rnaset2 | ribonuclease T2" />
    <Graphics CenterX="1483.3333333333333" CenterY="1146.6666666666667" Width="106.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="68195" />
  </DataNode>
  <DataNode TextLabel="Ddx19a" GraphId="e37" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Ddx19a | DEAD (Asp-Glu-Ala-Asp) box polypeptide..." />
    <Graphics CenterX="1636.6666666666667" CenterY="1426.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="13680" />
  </DataNode>
  <DataNode TextLabel="Adam5" GraphId="e3c" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Adam5 | a disintegrin and metalloprotease domai..." />
    <Graphics CenterX="670.0" CenterY="1610.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="11499" />
  </DataNode>
  <DataNode TextLabel="Mrpl11" GraphId="e3d" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Mrpl11 | mitochondrial ribosomal protein L11" />
    <Graphics CenterX="1773.3333333333333" CenterY="1246.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="66419" />
  </DataNode>
  <DataNode TextLabel="Srpk1" GraphId="e3e" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">PMID: 12773558</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Srpk1 | serine/arginine-rich protein specific k..." />
    <Graphics CenterX="1616.6666666666667" CenterY="646.6666666666666" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="20815" />
  </DataNode>
  <DataNode TextLabel="AI467299" GraphId="e41" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="AI467299 | expressed sequence AI467299" />
    <Graphics CenterX="516.6666666666666" CenterY="1610.0" Width="63.333333333333336" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="106604" />
  </DataNode>
  <DataNode TextLabel="Snrpf" GraphId="e42" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Snrpf | small nuclear ribonucleoprotein polypep..." />
    <Graphics CenterX="670.0" CenterY="286.6666666666667" Width="73.33333333333333" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="69878" />
  </DataNode>
  <DataNode TextLabel="1600023H17Rik" GraphId="e44" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="RIKEN cDNA 1600023H17 gene" />
    <Graphics CenterX="70.0" CenterY="1410.0" Width="100.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="MGI" ID="MGI:1922893" />
  </DataNode>
  <DataNode TextLabel="Pspc1" GraphId="e47" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pspc1 | paraspeckle protein 1" />
    <Graphics CenterX="953.3333333333334" CenterY="1366.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="66645" />
  </DataNode>
  <DataNode TextLabel="5730555F13Rik" GraphId="e48" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="5730555F13Rik | RIKEN cDNA 5730555F13 gene" />
    <Graphics CenterX="370.0" CenterY="1570.0" Width="100.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="66660" />
  </DataNode>
  <DataNode TextLabel="Srp19" GraphId="e4a" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Srp19 | signal recognition particle 19" />
    <Graphics CenterX="1906.6666666666667" CenterY="1683.3333333333333" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="66384" />
  </DataNode>
  <DataNode TextLabel="Rpl19" GraphId="e4c" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Rpl19 | ribosomal protein L19" />
    <Graphics CenterX="1773.3333333333333" CenterY="1803.3333333333333" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="19921" />
  </DataNode>
  <DataNode TextLabel="Rps13" GraphId="e4f" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Rps13 | ribosomal protein S13" />
    <Graphics CenterX="1906.6666666666667" CenterY="1323.3333333333333" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="68052" />
  </DataNode>
  <DataNode TextLabel="Fmr1" GraphId="e50" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Fmr1 | fragile X mental retardation syndrome 1 ..." />
    <Graphics CenterX="1636.6666666666667" CenterY="1766.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="14265" />
  </DataNode>
  <DataNode TextLabel="Pcbp3" GraphId="e53" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pcbp3 | poly(rC) binding protein 3" />
    <Graphics CenterX="1773.3333333333333" CenterY="1526.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="59093" />
  </DataNode>
  <DataNode TextLabel="LSMD1_MOUSE" GraphId="e58" Type="GeneProduct">
    <Graphics CenterX="2000.0" CenterY="683.3333333333334" Width="100.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Uniprot-TrEMBL" ID="Q9D2U5" />
  </DataNode>
  <DataNode TextLabel="AI314192" GraphId="e59" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="expressed sequence AI314192" />
    <Graphics CenterX="516.6666666666666" CenterY="1530.0" Width="63.333333333333336" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="MGI" ID="MGI:2147861" />
  </DataNode>
  <DataNode TextLabel="Poldip3" GraphId="e5b" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Poldip3 | polymerase (DNA-directed) delta int..." />
    <Graphics CenterX="953.3333333333334" CenterY="1546.6666666666667" Width="106.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="73826" />
  </DataNode>
  <DataNode TextLabel="Mettl3" GraphId="e5d" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Mettl3 | methyltransferase-like 3" />
    <Graphics CenterX="366.6666666666667" CenterY="263.3333333333333" Width="48.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="56335" />
  </DataNode>
  <DataNode TextLabel="2610023M21Rik" GraphId="e5e" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="RIKEN cDNA 2610023M21 gene" />
    <Graphics CenterX="216.66666666666666" CenterY="1350.0" Width="106.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="MGI" ID="MGI:1924186" />
  </DataNode>
  <DataNode TextLabel="2600011C06Rik" GraphId="e5f" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="2600011C06Rik | RIKEN cDNA 2600011C06 gene" />
    <Graphics CenterX="216.66666666666666" CenterY="1190.0" Width="100.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="67039" />
  </DataNode>
  <DataNode TextLabel="Exosc5" GraphId="e62" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Exosc5 | exosome component 5" />
    <Graphics CenterX="1636.6666666666667" CenterY="1406.6666666666667" Width="100.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="27998" />
  </DataNode>
  <DataNode TextLabel="4930422M05Rik" GraphId="e63" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="RIKEN cDNA 4930422M05 gene" />
    <Graphics CenterX="370.0" CenterY="1270.0" Width="106.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="MGI" ID="MGI:2442597" />
  </DataNode>
  <DataNode TextLabel="Lsm11" GraphId="e64" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Lsm11 | U7 snRNP-specific Sm-like protein LSM11..." />
    <Graphics CenterX="2000.0" CenterY="623.3333333333334" Width="100.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="72290" />
  </DataNode>
  <DataNode TextLabel="Ppm1g" GraphId="e67" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">PMID: 12773558</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Ppm1g | protein phosphatase 1G (formerly 2C) ..." />
    <Graphics CenterX="1616.6666666666667" CenterY="733.3333333333334" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="14208" />
  </DataNode>
  <DataNode TextLabel="3000004N20Rik" GraphId="e6a" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="3000004N20Rik | RIKEN cDNA 3000004N20 gene" />
    <Graphics CenterX="216.66666666666666" CenterY="1730.0" Width="106.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="72397" />
  </DataNode>
  <DataNode TextLabel="2700077B20Rik" GraphId="e6b" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="RIKEN cDNA 2700077B20 gene" />
    <Graphics CenterX="216.66666666666666" CenterY="1550.0" Width="106.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="MGI" ID="MGI:1923845" />
  </DataNode>
  <DataNode TextLabel="AI462171" GraphId="e6e" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="AI462171 | expressed sequence AI462171" />
    <Graphics CenterX="516.6666666666666" CenterY="1590.0" Width="63.333333333333336" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="103232" />
  </DataNode>
  <DataNode TextLabel="1700009P03Rik" GraphId="e71" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="1700009P03Rik | RIKEN cDNA 1700009P03 gene" />
    <Graphics CenterX="70.0" CenterY="1450.0" Width="100.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="74213" />
  </DataNode>
  <DataNode TextLabel="Rbm16" GraphId="e76" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Rbm16 | RNA binding motif protein 16" />
    <Graphics CenterX="953.3333333333334" CenterY="1786.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="106583" />
  </DataNode>
  <DataNode TextLabel="Cyp4f18" GraphId="e78" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Cyp4f18 | cytochrome P450 family 4 subfamily..." />
    <Graphics CenterX="810.0" CenterY="1146.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="72054" />
  </DataNode>
  <DataNode TextLabel="Oas2" GraphId="e7b" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Oas2 | 2â-5â oligoadenylate synthetase 2" />
    <Graphics CenterX="1773.3333333333333" CenterY="1406.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="246728" />
  </DataNode>
  <DataNode TextLabel="Rnmtl1" GraphId="e7f" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Rnmtl1 | RNA methyltransferase like 1" />
    <Graphics CenterX="1483.3333333333333" CenterY="1666.6666666666667" Width="106.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="67390" />
  </DataNode>
  <DataNode TextLabel="Tdrd7" GraphId="e80" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Tdrd7 | tudor domain containing 7" />
    <Graphics CenterX="370.0" CenterY="1550.0" Width="100.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="100121" />
  </DataNode>
  <DataNode TextLabel="V1rc17" GraphId="e85" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="V1rc17 | vomeronasal 1 receptor C17" />
    <Graphics CenterX="1183.3333333333333" CenterY="1166.6666666666667" Width="66.66460666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="171190" />
  </DataNode>
  <DataNode TextLabel="D830027H13Rik" GraphId="e8a" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="RIKEN cDNA D830027H13 gene" />
    <Graphics CenterX="670.0" CenterY="1570.0" Width="106.6634" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="MGI" ID="MGI:2445140" />
  </DataNode>
  <DataNode TextLabel="Hnrph1" GraphId="e8b" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Hnrph1 | heterogeneous nuclear ribonucleoprotei..." />
    <Graphics CenterX="423.3333333333333" CenterY="333.3333333333333" Width="66.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="59013" />
  </DataNode>
  <DataNode TextLabel="Cstf2t" GraphId="e8d" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Cstf2t | cleavage stimulation factor 3â pre-R..." />
    <Graphics CenterX="670.0" CenterY="1730.0" Width="100.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="83410" />
  </DataNode>
  <DataNode TextLabel="Rnmt" GraphId="e8e" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Rnmt | RNA (guanine-7-) methyltransferase" />
    <Graphics CenterX="100.0" CenterY="136.66666666666666" Width="53.333333333333336" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="67897" />
  </DataNode>
  <DataNode TextLabel="SRrp40" GraphId="e8f" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">FUSI MOUSE PMID: 11684676</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="SRrp40" />
    <Graphics CenterX="1820.0" CenterY="966.6666666666666" Width="66.73333333333333" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="" ID="" />
  </DataNode>
  <DataNode TextLabel="1500011J06Rik" GraphId="e94" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="1500011J06Rik | RIKEN cDNA 1500011J06 gene" />
    <Graphics CenterX="1616.6666666666667" CenterY="946.6666666666666" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="208606" />
  </DataNode>
  <DataNode TextLabel="Ddx6" GraphId="e95" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Ddx6 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 6..." />
    <Graphics CenterX="1636.6666666666667" CenterY="1646.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="13209" />
  </DataNode>
  <DataNode TextLabel="Rbm3" GraphId="e99" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Rbm3 | RNA binding motif protein 3" />
    <Graphics CenterX="953.3333333333334" CenterY="1606.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="19652" />
  </DataNode>
  <DataNode TextLabel="Boll" GraphId="e9c" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Boll | bol boule-like (Drosophila)" />
    <Graphics CenterX="370.0" CenterY="1390.0" Width="100.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="75388" />
  </DataNode>
  <DataNode TextLabel="Srp54" GraphId="e9d" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">PMID: 14729963</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Srp54 | signal recognition particle 54" />
    <Graphics CenterX="1616.6666666666667" CenterY="966.6666666666666" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="24067" />
  </DataNode>
  <DataNode TextLabel="Smc1l1" GraphId="ea0" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Smc1l1 | SMC (structural maintenance of chromos..." />
    <Graphics CenterX="1053.3333333333333" CenterY="290.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="24061" />
  </DataNode>
  <DataNode TextLabel="Hrmt1l1" GraphId="ea4" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Hrmt1l1 | heterogeneous nuclear ribonucleoprote..." />
    <Graphics CenterX="1816.6666666666667" CenterY="790.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="15468" />
  </DataNode>
  <DataNode TextLabel="Syncrip" GraphId="eb0" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Syncrip | synaptotagmin binding cytoplasmic R..." />
    <Graphics CenterX="953.3333333333334" CenterY="1286.6666666666667" Width="100.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="56403" />
  </DataNode>
  <DataNode TextLabel="9130414A06Rik" GraphId="eb1" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="RIKEN cDNA 9130414A06 gene" />
    <Graphics CenterX="370.0" CenterY="1750.0" Width="100.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="MGI" ID="MGI:1918855" />
  </DataNode>
  <DataNode TextLabel="D1Pas1-rs1" GraphId="eb5" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="D1Pas1-rs1" />
    <Graphics CenterX="1636.6666666666667" CenterY="1346.6666666666667" Width="100.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="MGI" ID="MGI:99524" />
  </DataNode>
  <DataNode TextLabel="2610102M01Rik" GraphId="eb9" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="RIKEN cDNA 2610102M01 gene" />
    <Graphics CenterX="216.66666666666666" CenterY="1430.0" Width="106.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="MGI" ID="MGI:1919730" />
  </DataNode>
  <DataNode TextLabel="Rbm18" GraphId="eba" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Rbm18 | RNA binding motif protein 18" />
    <Graphics CenterX="70.0" CenterY="1630.0" Width="100.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="67889" />
  </DataNode>
  <DataNode TextLabel="Pum2" GraphId="ebc" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pum2 | pumilio 2 (Drosophila)" />
    <Graphics CenterX="1773.3333333333333" CenterY="1666.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="80913" />
  </DataNode>
  <DataNode TextLabel="Dazap1" GraphId="ec1" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Dazap1 | DAZ associated protein 1" />
    <Graphics CenterX="810.0" CenterY="1266.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="70248" />
  </DataNode>
  <DataNode TextLabel="6720478K01Rik" GraphId="ec5" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="RIKEN cDNA 6720478K01 gene" />
    <Graphics CenterX="370.0" CenterY="1690.0" Width="100.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="MGI" ID="MGI:1925151" />
  </DataNode>
  <DataNode TextLabel="Tia1" GraphId="ec7" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Tia1 | cytotoxic granule-associated RNA binding..." />
    <Graphics CenterX="1066.6666666666667" CenterY="1686.6666666666667" Width="66.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="21841" />
  </DataNode>
  <DataNode TextLabel="Qk" GraphId="ecd" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Qk | quaking" />
    <Graphics CenterX="1773.3333333333333" CenterY="1686.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="19317" />
  </DataNode>
  <DataNode TextLabel="Dhx15" GraphId="ece" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Dhx15 | DEAH (Asp-Glu-Ala-His) box polypeptide ..." />
    <Graphics CenterX="1816.6666666666667" CenterY="606.6666666666666" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="13204" />
  </DataNode>
  <DataNode TextLabel="Snrpg" GraphId="ecf" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Snrpg | small nuclear ribonucleoprotein polypep..." />
    <Graphics CenterX="670.0" CenterY="306.6666666666667" Width="73.33333333333333" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="68011" />
  </DataNode>
  <DataNode TextLabel="Lsm8" GraphId="ed1" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Lsm8 | LSM8 homolog U6 small nuclear RNA asso..." />
    <Graphics CenterX="1483.3333333333333" CenterY="1306.6666666666667" Width="106.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="76522" />
  </DataNode>
  <DataNode TextLabel="Lsm1" GraphId="ed6" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Lsm1 | LSM1 homolog U6 small nuclear RNA asso..." />
    <Graphics CenterX="1483.3333333333333" CenterY="1586.6666666666667" Width="106.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="67207" />
  </DataNode>
  <DataNode TextLabel="Rbpms2" GraphId="ed8" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Rbpms2 | RNA binding protein with multiple spli..." />
    <Graphics CenterX="70.0" CenterY="1750.0" Width="100.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="71973" />
  </DataNode>
  <DataNode TextLabel="Rbm17" GraphId="ed9" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Rbm17 | RNA binding motif protein 17" />
    <Graphics CenterX="216.66666666666666" CenterY="1490.0" Width="106.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="76938" />
  </DataNode>
  <DataNode TextLabel="Rnu2" GraphId="eda" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Rnu2 | U2 small nuclear RNA" />
    <Graphics CenterX="1773.3333333333333" CenterY="1763.3333333333333" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="19848" />
  </DataNode>
  <DataNode TextLabel="Rnpepl1" GraphId="edc" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Rnpepl1 | arginyl aminopeptidase (aminopeptidas..." />
    <Graphics CenterX="70.0" CenterY="1250.0" Width="100.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="108657" />
  </DataNode>
  <DataNode TextLabel="AI255847" GraphId="ee3" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="expressed sequence AI255847" />
    <Graphics CenterX="516.6666666666666" CenterY="1470.0" Width="63.333333333333336" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="MGI" ID="MGI:2138184" />
  </DataNode>
  <DataNode TextLabel="Nhp2l1" GraphId="ee4" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Nhp2l1" />
    <Graphics CenterX="696.6666666666666" CenterY="643.3333333333334" Width="73.33333333333333" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="20826" />
  </DataNode>
  <DataNode TextLabel="Lsm2" GraphId="ee7" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Lsm2 | LSM2 homolog U6 small nuclear RNA asso..." />
    <Graphics CenterX="906.6666666666666" CenterY="643.3333333333334" Width="73.33333333333333" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="27756" />
  </DataNode>
  <DataNode TextLabel="1810035L17Rik" GraphId="eee" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="1810035L17Rik | RIKEN cDNA 1810035L17 gene" />
    <Graphics CenterX="70.0" CenterY="1570.0" Width="100.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="380773" />
  </DataNode>
  <DataNode TextLabel="Abcb4" GraphId="eef" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Abcb4 | ATP-binding cassette sub-family B (MD..." />
    <Graphics CenterX="670.0" CenterY="1690.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="18670" />
  </DataNode>
  <DataNode TextLabel="Tmed10" GraphId="ef3" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Tmp21" />
    <Graphics CenterX="1616.6666666666667" CenterY="886.6666666666666" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="68581" />
  </DataNode>
  <DataNode TextLabel="Srp14" GraphId="ef5" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Srp14 | signal recognition particle 14" />
    <Graphics CenterX="1906.6666666666667" CenterY="1663.3333333333333" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="20813" />
  </DataNode>
  <DataNode TextLabel="Rpl37" GraphId="ef6" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Rpl37 | ribosomal protein L37" />
    <Graphics CenterX="1906.6666666666667" CenterY="1203.3333333333333" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="67281" />
  </DataNode>
  <DataNode TextLabel="Ddx5" GraphId="ef8" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Ddx5 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 5..." />
    <Graphics CenterX="1636.6666666666667" CenterY="1606.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="13207" />
  </DataNode>
  <DataNode TextLabel="Hnrpc" GraphId="efd" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Hnrpc | heterogeneous nuclear ribonucleoprotein..." />
    <Graphics CenterX="323.3333333333333" CenterY="413.3333333333333" Width="69.33333333333333" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="15381" />
  </DataNode>
  <DataNode TextLabel="4930429A22Rik" GraphId="eff" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="4930429A22Rik | RIKEN cDNA 4930429A22 gene" />
    <Graphics CenterX="1483.3333333333333" CenterY="1686.6666666666667" Width="106.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="208718" />
  </DataNode>
  <DataNode TextLabel="Ddx21" GraphId="f02" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Ddx21 | DEAD (Asp-Glu-Ala-Asp) box polypeptide ..." />
    <Graphics CenterX="1636.6666666666667" CenterY="1446.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="56200" />
  </DataNode>
  <DataNode TextLabel="Fusip1" GraphId="f05" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Fusip1 | FUS interacting protein (serine-argini..." />
    <Graphics CenterX="1616.6666666666667" CenterY="906.6666666666666" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="14105" />
  </DataNode>
  <DataNode TextLabel="1810036E18Rik" GraphId="f06" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="RIKEN cDNA 1810036E18 gene" />
    <Graphics CenterX="70.0" CenterY="1610.0" Width="100.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="MGI" ID="MGI:1925734" />
  </DataNode>
  <DataNode TextLabel="Fbl" GraphId="f08" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Fbl | fibrillarin" />
    <Graphics CenterX="1636.6666666666667" CenterY="1746.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="14113" />
  </DataNode>
  <DataNode TextLabel="Sfrs2" GraphId="f0a" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Sfrs2" />
    <Graphics CenterX="773.3333333333334" CenterY="270.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="20382" />
  </DataNode>
  <DataNode TextLabel="Pabpn1" GraphId="f0c" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pabpn1 | poly(A) binding protein nuclear 1" />
    <Graphics CenterX="1423.3333333333333" CenterY="136.66666666666666" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="54196" />
  </DataNode>
  <DataNode TextLabel="9430070C08Rik" GraphId="f11" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="RIKEN cDNA 9430070C08 gene" />
    <Graphics CenterX="370.0" CenterY="1770.0" Width="100.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="MGI" ID="MGI:1924605" />
  </DataNode>
  <DataNode TextLabel="Oas1b" GraphId="f12" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Oas1b | 2â-5â oligoadenylate synthetase 1B" />
    <Graphics CenterX="1773.3333333333333" CenterY="1366.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="23961" />
  </DataNode>
  <DataNode TextLabel="4932702K14Rik" GraphId="f15" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="4932702K14Rik | RIKEN cDNA 4932702K14 gene" />
    <Graphics CenterX="370.0" CenterY="1450.0" Width="100.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="67543" />
  </DataNode>
  <DataNode TextLabel="Hnrpab" GraphId="f18" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Hnrpab | heterogeneous nuclear ribonucleoprotei..." />
    <Graphics CenterX="323.3333333333333" CenterY="393.3333333333333" Width="69.33333333333333" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="15384" />
  </DataNode>
  <DataNode TextLabel="Sfrs16" GraphId="f1b" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Sfrs16 | splicing factor arginine/serine-rich..." />
    <Graphics CenterX="1616.6666666666667" CenterY="866.6666666666666" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="53609" />
  </DataNode>
  <DataNode TextLabel="Pcbp4" GraphId="f1e" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pcbp4 | poly(rC) binding protein 4" />
    <Graphics CenterX="1773.3333333333333" CenterY="1546.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="59092" />
  </DataNode>
  <DataNode TextLabel="AA522010" GraphId="f20" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="expressed sequence AA522010" />
    <Graphics CenterX="516.6666666666666" CenterY="1190.0" Width="66.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="MGI" ID="MGI:2141367" />
  </DataNode>
  <DataNode TextLabel="2310046H11Rik" GraphId="f24" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="RIKEN cDNA 2310046H11 gene" />
    <Graphics CenterX="70.0" CenterY="1730.0" Width="100.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="MGI" ID="MGI:1922955" />
  </DataNode>
  <DataNode TextLabel="2610101N10Rik" GraphId="f29" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="2610101N10Rik | RIKEN cDNA 2610101N10 gene" />
    <Graphics CenterX="216.66666666666666" CenterY="1390.0" Width="106.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="67958" />
  </DataNode>
  <DataNode TextLabel="AI843301" GraphId="f2f" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="expressed sequence AI843301" />
    <Graphics CenterX="516.6666666666666" CenterY="1690.0" Width="63.333333333333336" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="MGI" ID="MGI:2146493" />
  </DataNode>
  <DataNode TextLabel="Ddx56" GraphId="f31" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Ddx56 | DEAD (Asp-Glu-Ala-Asp) box polypeptide ..." />
    <Graphics CenterX="1636.6666666666667" CenterY="1626.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="52513" />
  </DataNode>
  <DataNode TextLabel="Msi1h" GraphId="f32" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Msi1h | Musashi homolog 1(Drosophila)" />
    <Graphics CenterX="953.3333333333334" CenterY="1226.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="17690" />
  </DataNode>
  <DataNode TextLabel="Sfrs10" GraphId="f33" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Sfrs10 | splicing factor arginine/serine-rich..." />
    <Graphics CenterX="1066.6666666666667" CenterY="1506.6666666666667" Width="66.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="20462" />
  </DataNode>
  <DataNode TextLabel="Cpeb3" GraphId="f39" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Cpeb3 | cytoplasmic polyadenylation element bin..." />
    <Graphics CenterX="810.0" CenterY="1186.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="208922" />
  </DataNode>
  <DataNode TextLabel="Hdp" GraphId="f3a" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="helix destabilizing protein" />
    <Graphics CenterX="810.0" CenterY="1646.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="MGI" ID="MGI:104612" />
  </DataNode>
  <DataNode TextLabel="AW260507" GraphId="f3b" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="expressed sequence AW260507" />
    <Graphics CenterX="670.0" CenterY="1190.0" Width="73.33333333333333" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="MGI" ID="MGI:2147361" />
  </DataNode>
  <DataNode TextLabel="Eral1" GraphId="f3d" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Eral1 | Era (G-protein)-like 1 (E. coli)" />
    <Graphics CenterX="810.0" CenterY="1466.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="57837" />
  </DataNode>
  <DataNode TextLabel="Hnrpd" GraphId="f3f" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Hnrpd | heterogeneous nuclear ribonucleoprotein..." />
    <Graphics CenterX="323.3333333333333" CenterY="433.3333333333333" Width="69.33333333333333" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="11991" />
  </DataNode>
  <DataNode TextLabel="5730557H03Rik" GraphId="f40" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="RIKEN cDNA 5730557H03 gene" />
    <Graphics CenterX="370.0" CenterY="1610.0" Width="100.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="MGI" ID="MGI:1917910" />
  </DataNode>
  <DataNode TextLabel="Adat1" GraphId="f43" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Adat1 | adenosine deaminase tRNA-specific 1" />
    <Graphics CenterX="1636.6666666666667" CenterY="1186.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="30947" />
  </DataNode>
  <DataNode TextLabel="Prpf18" GraphId="f44" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Prpf18 | PRP18 pre-mRNA processing factor 18 ho..." />
    <Graphics CenterX="1026.6666666666667" CenterY="590.0" Width="53.333333333333336" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="67229" />
  </DataNode>
  <DataNode TextLabel="2810411C16Rik" GraphId="f45" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="RIKEN cDNA 2810411C16 gene" />
    <Graphics CenterX="216.66666666666666" CenterY="1650.0" Width="106.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="MGI" ID="MGI:1916505" />
  </DataNode>
  <DataNode TextLabel="2410013L13Rik" GraphId="f49" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="RIKEN cDNA 2410013L13 gene" />
    <Graphics CenterX="70.0" CenterY="1790.0" Width="100.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="MGI" ID="MGI:2149671" />
  </DataNode>
  <DataNode TextLabel="Rbm14" GraphId="f4d" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Rbm14 | RNA binding motif protein 14" />
    <Graphics CenterX="953.3333333333334" CenterY="1766.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="56275" />
  </DataNode>
  <DataNode TextLabel="Rnu1b2" GraphId="f4f" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Rnu1b2 | U1b2 small nuclear RNA" />
    <Graphics CenterX="1066.6666666666667" CenterY="1466.6666666666667" Width="66.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="19845" />
  </DataNode>
  <DataNode TextLabel="Cstf2" GraphId="f52" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Cstf2 | cleavage stimulation factor 3â pre-RN..." />
    <Graphics CenterX="1536.6666666666667" CenterY="173.33333333333334" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="108062" />
  </DataNode>
  <DataNode TextLabel="Sca1" GraphId="f54" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Sca1 | spinocerebellar ataxia 1 homolog (human)..." />
    <Graphics CenterX="1906.6666666666667" CenterY="1563.3333333333333" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="20238" />
  </DataNode>
  <DataNode TextLabel="Snrpe" GraphId="f56" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Snrpe | small nuclear ribonucleoprotein E" />
    <Graphics CenterX="670.0" CenterY="266.6666666666667" Width="73.33333333333333" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="20643" />
  </DataNode>
  <DataNode TextLabel="4632417O19Rik" GraphId="f58" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="RIKEN cDNA 4632417O19 gene" />
    <Graphics CenterX="370.0" CenterY="1170.0" Width="106.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="MGI" ID="MGI:1925510" />
  </DataNode>
  <DataNode TextLabel="Tsn" GraphId="f59" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Tsn | translin" />
    <Graphics CenterX="2030.0" CenterY="1186.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="22099" />
  </DataNode>
  <DataNode TextLabel="Thoc4" GraphId="f5b" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Thoc4 | THO complex 4" />
    <Graphics CenterX="1066.6666666666667" CenterY="1266.6666666666667" Width="66.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="21681" />
  </DataNode>
  <DataNode TextLabel="Brunol6" GraphId="f60" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Brunol6 | bruno-like 6 RNA binding protein (D..." />
    <Graphics CenterX="370.0" CenterY="1650.0" Width="100.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="76183" />
  </DataNode>
  <DataNode TextLabel="D12Mgi40" GraphId="f61" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="D12Mgi40 | DNA Segment Chr 12 Mouse Genome I..." />
    <Graphics CenterX="516.6666666666666" CenterY="1770.0" Width="66.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="104925" />
  </DataNode>
  <DataNode TextLabel="Snrpd3" GraphId="f66" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Snrpd3 | small nuclear ribonucleoprotein D3" />
    <Graphics CenterX="576.6666666666666" CenterY="326.6666666666667" Width="73.33333333333333" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="67332" />
  </DataNode>
  <DataNode TextLabel="Hnrpm" GraphId="f6c" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Hnrpm | heterogeneous nuclear ribonucleoprotein..." />
    <Graphics CenterX="423.3333333333333" CenterY="413.3333333333333" Width="66.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="76936" />
  </DataNode>
  <DataNode TextLabel="Sfrs6" GraphId="f6d" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Sfrs6" />
    <Graphics CenterX="863.3333333333334" CenterY="250.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="67996" />
  </DataNode>
  <DataNode TextLabel="1700047G05Rik" GraphId="f6f" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="RIKEN cDNA 1700047G05 gene" />
    <Graphics CenterX="70.0" CenterY="1510.0" Width="100.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="MGI" ID="MGI:1914568" />
  </DataNode>
  <DataNode TextLabel="Rps7" GraphId="f72" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Rps7 | ribosomal protein S7" />
    <Graphics CenterX="1906.6666666666667" CenterY="1523.3333333333333" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="20115" />
  </DataNode>
  <DataNode TextLabel="Matr3-ps2" GraphId="f7a" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Matr3-ps2 | matrin 3 pseudogene 2" />
    <Graphics CenterX="953.3333333333334" CenterY="1166.6666666666667" Width="66.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="17186" />
  </DataNode>
  <DataNode TextLabel="Cpsf4" GraphId="f80" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Cpsf4 | cleavage and polyadenylation specific f..." />
    <Graphics CenterX="1303.3333333333333" CenterY="193.33333333333334" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="54188" />
  </DataNode>
  <DataNode TextLabel="1110034O07Rik" GraphId="f81" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="1110034O07Rik | RIKEN cDNA 1110034O07 gene" />
    <Graphics CenterX="70.0" CenterY="1270.0" Width="100.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="68744" />
  </DataNode>
  <DataNode TextLabel="AW107884" GraphId="f85" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="expressed sequence AW107884" />
    <Graphics CenterX="670.0" CenterY="1170.0" Width="73.33333333333333" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="MGI" ID="MGI:2140554" />
  </DataNode>
  <DataNode TextLabel="2600016F06Rik" GraphId="f86" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="RIKEN cDNA 2600016F06 gene" />
    <Graphics CenterX="216.66666666666666" CenterY="1250.0" Width="100.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="MGI" ID="MGI:1913821" />
  </DataNode>
  <DataNode TextLabel="Sf3b5" GraphId="f8a" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Sf3b5 | splicing factor 3b subunit 5" />
    <Graphics CenterX="806.6666666666666" CenterY="506.6666666666667" Width="66.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="66125" />
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  <DataNode TextLabel="Ncbp1" GraphId="f8c" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Ncbp1 | nuclear cap binding protein subunit 1" />
    <Graphics CenterX="366.6666666666667" CenterY="203.33333333333334" Width="48.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="110519" />
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  <DataNode TextLabel="Nsep1" GraphId="f92" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Nsep1 | nuclease sensitive element binding prot..." />
    <Graphics CenterX="966.6666666666666" CenterY="270.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="22608" />
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  <DataNode TextLabel="Sfrs12" GraphId="f95" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">PMID: 14559993.  SRrp86 is a unique member of the SR protein superfamily containing one RNA recognition motif and two serine-arginine (SR)-rich domains separated by an unusual glutamic acid-lysine (EK)-rich region. Previously, we showed that SRrp86 could regulate alternative splicing by both positively and negatively modulating the activity of other SR proteins and that the unique EK domain could inhibit both constitutive and alternative splicing. These functions were most consistent with the model in which SRrp86 functions by interacting with and thereby modulating the activity of target proteins. To identify the specific proteins that interact with SRrp86, we used a yeast two-hybrid library screen and immunoprecipitation coupled to mass spectrometry. We show that SRrp86 interacts with all of the core SR proteins, as well as a subset of other splicing regulatory proteins, including SAF-B, hnRNP G, YB-1, and p72. In contrast to previous results that showed activation of SRp20 by SRrp86, we now show that SAF-B, hnRNP G, and 9G8 all antagonize the activity of SRrp86. Overall, we conclude that not only does SRrp86 regulate SR protein activity but that it is, in turn, regulated by other splicing factors to control alternative splice site selection.</Comment>
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    <Xref Database="Entrez Gene" ID="218543" />
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  <DataNode TextLabel="Ncl" GraphId="f97" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Ncl | nucleolin" />
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    <Xref Database="Entrez Gene" ID="17975" />
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  <DataNode TextLabel="Rdbp" GraphId="f99" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Rdbp | RD RNA-binding protein" />
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    <Xref Database="Entrez Gene" ID="27632" />
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  <DataNode TextLabel="Sfrs7" GraphId="f9a" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Sfrs7" />
    <Graphics CenterX="863.3333333333334" CenterY="270.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="225027" />
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  <DataNode TextLabel="Rbms1" GraphId="f9b" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Rbms1 | RNA binding motif single stranded int..." />
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    <Xref Database="Entrez Gene" ID="56878" />
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  <DataNode TextLabel="Rps11" GraphId="f9e" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Rps11 | ribosomal protein S11" />
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    <Xref Database="Entrez Gene" ID="27207" />
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  <DataNode TextLabel="Rps6" GraphId="fa1" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Rps6 | ribosomal protein S6" />
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    <Xref Database="Entrez Gene" ID="20104" />
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  <DataNode TextLabel="Npm1" GraphId="fa3" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Npm1 | nucleophosmin 1" />
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    <Xref Database="Entrez Gene" ID="18148" />
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  <DataNode TextLabel="Dicer1" GraphId="fab" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Dicer1 | Dicer1 Dcr-1 homolog (Drosophila)" />
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  <DataNode TextLabel="Rbmx2" GraphId="fae" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Rbmx2 | RNA binding motif protein X-linked 2..." />
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  <DataNode TextLabel="Tlr5" GraphId="fbb" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Tlr5 | toll-like receptor 5" />
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  <DataNode TextLabel="Snrpa1" GraphId="fbd" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Snrpa1 | small nuclear ribonucleoprotein polype..." />
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  <DataNode TextLabel="2810441O16Rik" GraphId="fc1" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="2810441O16Rik | RIKEN cDNA 2810441O16 gene" />
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  <DataNode TextLabel="Rbmxrt" GraphId="fc5" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Rbmxrt | RNA binding motif protein X chromoso..." />
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  <DataNode TextLabel="Supt5h" GraphId="fc9" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Supt5h | suppressor of Ty 5 homolog (S. cerevis..." />
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  <DataNode TextLabel="Rbm5" GraphId="fcd" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Rbm5 | RNA binding motif protein 5" />
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  <DataNode TextLabel="Slbp" GraphId="fcf" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Slbp | stem-loop binding protein" />
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  <DataNode TextLabel="Wdr9" GraphId="fd5" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Wdr9 | WD repeat domain 9" />
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  <DataNode TextLabel="Ilkap" GraphId="fdb" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Ilkap | integrin-linked kinase-associated serin..." />
    <Graphics CenterX="70.0" CenterY="1230.0" Width="100.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="67444" />
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  <DataNode TextLabel="2700028P07Rik" GraphId="fdd" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="RIKEN cDNA 2700028P07 gene" />
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    <Xref Database="MGI" ID="MGI:1924055" />
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  <DataNode TextLabel="1500012C14Rik" GraphId="fdf" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="RIKEN cDNA 1500012C14 gene" />
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  <DataNode TextLabel="Myef2" GraphId="fe3" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Myef2 | myelin basic protein expression factor..." />
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  <DataNode TextLabel="Clk1" GraphId="fe4" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Clk1 | CDC-like kinase 1" />
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  <DataNode TextLabel="Hnrpll" GraphId="ff3" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Hnrpll | heterogeneous nuclear ribonucleoprotei..." />
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  <DataNode TextLabel="Papolb" GraphId="ff4" Type="GeneProduct">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Papolb | poly (A) polymerase beta (testis speci..." />
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  <DataNode TextLabel="AA407033" GraphId="ff5" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
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  <DataNode TextLabel="AI255212" GraphId="ff7" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="AI255212 | expressed sequence AI255212" />
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  <DataNode TextLabel="Rbm9" GraphId="ffd" Type="GeneProduct">
    <Comment Source="GenMAPP remarks">Derived from InterPro</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Rbm9 | RNA binding motif protein 9" />
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    <Comment Source="GenMAPP remarks">Endonucleolytic cleavage separates the pre-mRNA into an upstream fragment destined to become the mature mRNA, and a downstream fragment that is rapidly degraded. Cleavage depends on two signals in the RNA, a highly conserved hexanucleotide, AAUAAA, 10 to 30 nucleotides upstream of the cleavage site, and a poorly conserved GU- or U-rich downstream element. Additional sequences, often upstream of AAUAAA, can enhance the efficiency of the reaction. Cleavage occurs most often after a CA dinucleotide. A single gene can have more than one 3â processing site.&#xD;
Cleavage is preceded by the assembly of a large processing complex, the composition of which is poorly defined. ATP, but not its hydrolysis, is required for assembly. Cleavage at the 3â-end of mRNAs depends on a number of protein factors. CPSF, a heterotetramer, binds specifically to the AAUAAA sequence. The heterotrimer CstF binds the downstream element. CF I, which appears to be composed of two subunits, one of several related larger polypeptides and a common smaller one, also binds RNA, but with unknown specificity. RNA recognition by these proteins is cooperative. Cleavage also requires CF II, composed of at least two subunits, and poly(A) polymerase, the enzyme synthesizing the poly(A) tail in the second step of the reaction. The polypeptide catalyzing the hydrolysis of the phosphodiester bond remains to be identified.&#xD;
&#xD;
Cleavage produces a 3â-OH on the upstream fragment and a 5â-phosphate on the downstream fragment. At some unknown point after cleavage, the downstream RNA fragment, CstF, CF I and CF II are thought to be released, whereas CPSF and poly(A) polymerase remain to carry out polyadenylation.&#xD;
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    <Comment Source="GenMAPP remarks">In addition to the methylation of the 5â-cap, there is methylation of internal nucleotides in the mRNA. This methylation can occur in translated and untranslated regions. One to three methyl groups have been seen per mRNA molecule, but methylation is non-stoichiometric. The most frequent methylation observed is at the N6 position of adenosine. The function of mRNA internal methylation, if any, is unknown. Krainer, A, 2003-06-05</Comment>
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  <Label TextLabel="AAUAAA" GraphId="b88">
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  </Label>
  <Label TextLabel="iPo" GraphId="b9f">
    <Comment Source="GenMAPP remarks">inorganic phosphate</Comment>
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  </Label>
  <Label TextLabel="CFI" GraphId="ba2">
    <Graphics CenterX="1613.3333333333333" CenterY="423.3333333333333" Width="22.333333333333332" Height="15.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="9" Valign="Middle" />
  </Label>
  <Label TextLabel="hnRNPs" GraphId="bac">
    <Graphics CenterX="276.6666666666667" CenterY="570.0" Width="50.333333333333336" Height="15.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="9" Valign="Middle" />
  </Label>
  <Label TextLabel="Rngtt (capping enzyme)" GraphId="baf">
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  </Label>
  <Label TextLabel="exon 2" GraphId="bc1">
    <Graphics CenterX="1246.6666666666667" CenterY="710.0" Width="38.333333333333336" Height="11.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontStyle="Italic" FontSize="8" Valign="Middle" />
  </Label>
  <Label TextLabel="RNA helicase A" GraphId="bc3">
    <Graphics CenterX="1016.6666666666666" CenterY="170.0" Width="97.33333333333333" Height="16.0" ZOrder="28672" FillColor="ffffff" FontStyle="Italic" FontSize="10" Valign="Middle" />
  </Label>
  <Label TextLabel="YYYY" GraphId="bc5">
    <Graphics CenterX="750.0" CenterY="866.6666666666666" Width="33.333333333333336" Height="15.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="9" Valign="Middle" />
  </Label>
  <Label TextLabel="CPSF" GraphId="bcd">
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  </Label>
  <Label TextLabel="3" GraphId="bf3">
    <Graphics CenterX="1150.0" CenterY="843.3333333333334" Width="12.333333333333334" Height="15.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="9" Valign="Middle" />
  </Label>
  <Label TextLabel="SR-binding sites" GraphId="c0c">
    <Comment Source="GenMAPP remarks">Cis-regulatory nucleotide splicing motifs, regulated by the binding of SR-proteins.  Include exonic splicing enhancer (ESE) and exonic splicing silencer (ESS) motifs.</Comment>
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  </Label>
  <Label TextLabel="CA" GraphId="c0d">
    <Graphics CenterX="1683.3333333333333" CenterY="316.6666666666667" Width="19.333333333333332" Height="12.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="8" Valign="Middle" />
  </Label>
  <Label TextLabel="Polr2a" GraphId="c14">
    <Graphics CenterX="166.66666666666666" CenterY="443.3333333333333" Width="42.333333333333336" Height="15.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="9" Valign="Middle" />
  </Label>
  <Label TextLabel="3" GraphId="c18">
    <Graphics CenterX="1706.6666666666667" CenterY="343.3333333333333" Width="12.333333333333334" Height="15.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="9" Valign="Middle" />
  </Label>
  <Label TextLabel="CPSF" GraphId="c1b">
    <Graphics CenterX="1676.6666666666667" CenterY="440.0" Width="35.333333333333336" Height="15.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="9" Valign="Middle" />
  </Label>
  <Label TextLabel="InterPro Domain Containing:" GraphId="c25">
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  </Label>
  <Label TextLabel="mRNA splicing (major pathway)" GraphId="c28">
    <Comment Source="GenMAPP remarks">The process in which excision of introns from the primary transcript of messenger RNA (mRNA) is followed by ligation of the two exon termini exposed by removal of each intron, is called mRNA splicing. Most of the mRNA is spliced by the major pathway, involving the U1, U2, U4, U5 and U6 snRNPs. A minor fraction, about 1 %, of the mRNAs are spliced via the U12 dependent pathway. Krainer, A, 2003-06-05</Comment>
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  </Label>
  <Label TextLabel="Poly(A)pb II" GraphId="c2d">
    <Graphics CenterX="1580.0" CenterY="270.0" Width="68.33333333333333" Height="15.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="9" Valign="Middle" />
  </Label>
  <Label TextLabel="3" GraphId="c32">
    <Graphics CenterX="383.8378123526639" CenterY="613.3333333333334" Width="12.333333333333334" Height="15.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="9" Valign="Middle" />
  </Label>
  <Label TextLabel="Misc." GraphId="c48">
    <Graphics CenterX="2003.3333333333333" CenterY="580.0" Width="37.333333333333336" Height="16.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="10" Valign="Middle" />
  </Label>
  <Label TextLabel="CstF" GraphId="c4a">
    <Graphics CenterX="1656.6666666666667" CenterY="253.33333333333334" Width="30.333333333333332" Height="15.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="9" Valign="Middle" />
  </Label>
  <Label TextLabel="RNA helicase" GraphId="c4b">
    <Graphics CenterX="933.3333333333334" CenterY="440.0" Width="84.33333333333333" Height="16.0" ZOrder="28672" FillColor="ffffff" FontStyle="Italic" FontSize="10" Valign="Middle" />
  </Label>
  <Label TextLabel="hnRNP regulators" GraphId="c4c">
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  </Label>
  <Label TextLabel="SR protein kinases" GraphId="c50">
    <Comment Source="GenMAPP remarks">Clk proteins can interact with and phosphorylate SR proteins.  These proteins are capable of autophosphorylation and may alter the subnuclear localization of SR proteins. While the Clk proteins phosphorylate RS domains, they themselves contain RS-like domains and are also known to be autophosphorylated on tyrosines.</Comment>
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  </Label>
  <Label TextLabel="Additional Factors" GraphId="c52">
    <Graphics CenterX="1060.0" CenterY="400.0" Width="110.33333333333333" Height="16.0" ZOrder="28672" FillColor="ffffff" FontStyle="Italic" FontSize="10" Valign="Middle" />
  </Label>
  <Label TextLabel="Regulation of" GraphId="c54">
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  </Label>
  <Label TextLabel="snRNP Sm core complex" GraphId="c5a">
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  </Label>
  <Label TextLabel="U6 snRNP" GraphId="c64">
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  </Label>
  <Label TextLabel="U2" GraphId="c67">
    <Graphics CenterX="1016.6666666666666" CenterY="816.6666666666666" Width="20.333333333333332" Height="15.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="9" Valign="Middle" />
  </Label>
  <Label TextLabel="3" GraphId="c68">
    <Graphics CenterX="1346.6666666666667" CenterY="546.6666666666666" Width="12.333333333333334" Height="15.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="9" Valign="Middle" />
  </Label>
  <Label TextLabel="5  G cap" GraphId="c79">
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  </Label>
  <Label TextLabel="Serine/Argenine Rich Proteins(SR)" GraphId="c85">
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  </Label>
  <Label TextLabel="SR-kinases" GraphId="c93">
    <Comment Source="GenMAPP remarks">Phosphorylates RS domains</Comment>
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  </Label>
  <Label TextLabel="5" GraphId="c97">
    <Graphics CenterX="1786.6666666666667" CenterY="343.3333333333333" Width="12.333333333333334" Height="15.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="9" Valign="Middle" />
  </Label>
  <Label TextLabel="Poly(A) polymerase alpha" GraphId="c99">
    <Graphics CenterX="1423.3333333333333" CenterY="160.0" Width="152.33333333333334" Height="16.0" ZOrder="28672" FillColor="ffffff" FontStyle="Italic" FontSize="10" Valign="Middle" />
  </Label>
  <Label TextLabel="Accessory Proteins" GraphId="c9d">
    <Graphics CenterX="1813.3333333333333" CenterY="490.0" Width="154.33333333333334" Height="19.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="12" Valign="Middle" />
  </Label>
  <Label TextLabel="65" GraphId="ca8">
    <Graphics CenterX="496.6666666666667" CenterY="793.3333333333334" Width="17.333333333333332" Height="12.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="8" Valign="Middle" />
  </Label>
  <Label TextLabel="3" GraphId="caa">
    <Graphics CenterX="860.0" CenterY="846.6666666666666" Width="12.333333333333334" Height="15.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="9" Valign="Middle" />
  </Label>
  <Label TextLabel="SR-repressor proteins" GraphId="cac">
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  </Label>
  <Label TextLabel="splicing factor SF3B" GraphId="cad">
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  </Label>
  <Label TextLabel="A" GraphId="cb2">
    <Graphics CenterX="1211.347103726987" CenterY="536.6666666666666" Width="13.333333333333334" Height="15.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="9" Valign="Middle" />
  </Label>
  <Label TextLabel="35" GraphId="cbe">
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  </Label>
  <Label TextLabel="Rnmt (methyltransferase)" GraphId="cc3">
    <Graphics CenterX="186.66666666666666" CenterY="423.3333333333333" Width="127.33333333333333" Height="12.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="8" Valign="Middle" />
  </Label>
  <Label TextLabel="5" GraphId="cc4">
    <Graphics CenterX="30.0" CenterY="473.3333333333333" Width="12.333333333333334" Height="15.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="9" Valign="Middle" />
  </Label>
  <Label TextLabel="right click on blue text for detailed information" GraphId="ccb">
    <Graphics CenterX="446.6666666666667" CenterY="30.0" Width="295.3333333333333" Height="16.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontStyle="Italic" FontSize="10" Valign="Middle" Color="0000ff" />
  </Label>
  <Label TextLabel="UG" GraphId="cea">
    <Graphics CenterX="1216.6666666666667" CenterY="640.0" Width="21.333333333333332" Height="15.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="9" Valign="Middle" />
  </Label>
  <Label TextLabel="3" GraphId="cec">
    <Graphics CenterX="30.0" CenterY="456.6666666666667" Width="12.333333333333334" Height="15.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="9" Valign="Middle" />
  </Label>
  <Label TextLabel="exon 1" GraphId="cf7">
    <Graphics CenterX="1253.3333333333333" CenterY="613.3333333333334" Width="38.333333333333336" Height="11.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontStyle="Italic" FontSize="8" Valign="Middle" />
  </Label>
  <Label TextLabel="YYYY" GraphId="cf9">
    <Graphics CenterX="1240.0" CenterY="536.6666666666666" Width="33.333333333333336" Height="15.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="9" Valign="Middle" />
  </Label>
  <Label TextLabel="3" GraphId="cfb">
    <Graphics CenterX="1300.0" CenterY="686.6666666666666" Width="12.333333333333334" Height="15.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="9" Valign="Middle" />
  </Label>
  <Label TextLabel="Additional SR proteins" GraphId="d05">
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  </Label>
  <Label TextLabel="(2c)" GraphId="d12">
    <Graphics CenterX="703.3333333333334" CenterY="113.33333333333333" Width="33.333333333333336" Height="18.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontStyle="Italic" FontSize="12" Valign="Middle" Color="ff0000" />
  </Label>
  <Label TextLabel="5" GraphId="d14">
    <Graphics CenterX="1576.6666666666667" CenterY="343.3333333333333" Width="12.333333333333334" Height="15.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="9" Valign="Middle" />
  </Label>
  <Label TextLabel="splicing factor SF3A" GraphId="d18">
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  </Label>
  <Label TextLabel="heterogeneous nuclear ribonucleoproteins" GraphId="d1b">
    <Graphics CenterX="373.3333333333333" CenterY="310.0" Width="246.33333333333334" Height="16.0" ZOrder="28672" FillColor="ffffff" FontStyle="Italic" FontSize="10" Valign="Middle" />
  </Label>
  <Label TextLabel="A" GraphId="d2a">
    <Graphics CenterX="450.0" CenterY="826.6666666666666" Width="13.333333333333334" Height="15.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="9" Valign="Middle" />
  </Label>
  <Label TextLabel="(1)" GraphId="d2e">
    <Graphics CenterX="26.666666666666668" CenterY="80.0" Width="25.333333333333332" Height="18.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontStyle="Italic" FontSize="12" Valign="Middle" Color="ff0000" />
  </Label>
  <Label TextLabel="Formation of the Spliceosomal B complex" GraphId="d37">
    <Comment Source="GenMAPP remarks">The formation of the B complex is ATP-dependent, and both the 5â and 3â splice sites are essential for B complex assembly. The U4 and U6 snRNPS are extensively base-paired, and this U4:U6 complex associates with the U5 snRNP to form a tri-snRNP particle. This tri-snRNP particle then binds to the spliceosomal A complex, to form the spliceosomal B complex. Krainer, A, 2003-06-05</Comment>
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  </Label>
  <Label TextLabel="SR-binding sites" GraphId="d52">
    <Graphics CenterX="550.0" CenterY="840.0" Width="85.33333333333333" Height="12.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="8" Valign="Middle" />
  </Label>
  <Label TextLabel="U2 snRNP" GraphId="d58">
    <Graphics CenterX="470.0" CenterY="736.6666666666666" Width="61.333333333333336" Height="15.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="9" Valign="Middle" />
  </Label>
  <Label TextLabel="Regulators" GraphId="d5b">
    <Graphics CenterX="1820.0" CenterY="853.3333333333334" Width="73.33333333333333" Height="16.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="10" Valign="Middle" />
  </Label>
  <Label TextLabel="RNAi pathway" GraphId="d5d">
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  </Label>
  <Label TextLabel="Formation of pre-mRNPs" GraphId="d6f">
    <Comment Source="GenMAPP remarks">After the nascent pre-mRNA undergoes the initial capping and methylation reactions, it gets associated with numerous factors, including the various heterogeneous nuclear ribonucleoproteins (hnRNPS), the nuclear Cap-Binding Complex, and many splicing factors that make the pre-mRNA a substrate for splicing, 3â-end processing, and in some cases editing. Krainer, A, 2003-06-05</Comment>
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  </Label>
  <Label TextLabel="(2b)" GraphId="d76">
    <Graphics CenterX="276.6666666666667" CenterY="293.3333333333333" Width="35.333333333333336" Height="18.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontStyle="Italic" FontSize="12" Valign="Middle" Color="ff0000" />
  </Label>
  <Label TextLabel="Poly(A)-binding protein II" GraphId="d87">
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  </Label>
  <Label TextLabel="A" GraphId="d8e">
    <Graphics CenterX="1210.4490345756624" CenterY="360.0" Width="13.333333333333334" Height="15.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="9" Valign="Middle" />
  </Label>
  <Label TextLabel="U2AF" GraphId="d95">
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  </Label>
  <Label TextLabel="exon 1" GraphId="da1">
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  </Label>
  <Label TextLabel="Primary RNA transcript" GraphId="dab">
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  </Label>
  <Label TextLabel="mRNA polyadenylation" GraphId="dad">
    <Comment Source="GenMAPP remarks">The upstream fragment generated by 3â cleavage of the pre-mRNA receives a poly(A) tail of approximately 250 AMP residues in a reaction depending on the AAUAAA sequence 10 to 30 nucleotides upstream of the 3â end. Polyadenylation is carried out by three proteins: Poly(A) polymerase carries the catalytic activity. The enzyme has no specificity for any particular RNA sequence, and it also has a very low affinity for the RNA.&#xD;
Under physiological conditions, the activity of poly(A) polymerase thus depends on two auxiliary factors, both of which bind to specific RNA sequences and recruit the enzyme by a direct contact. One of these proteins is the heterotetrameric CPSF, which binds the AAUAAA sequence and is also essential for 3â cleavage. The second is the nuclear poly(A) binding protein (PABPN1), which binds the growing poly(A) tails once this has reached a length of about ten nucleotides. Stimulation of poly(A) polymerase by both proteins is synergistic and results in processive elongation of the RNA, i.e. the polymerase adds AMP residues without dissociating from the RNA. The processive reaction is terminated when the tail has reached a length of about 250 nucleotides.&#xD;
&#xD;
Cleavage produces a 3â-OH on the upstream fragment and a 5â-phosphate on the downstream fragment. At some unknown point after cleavage, the downstream RNA fragment, CstF, CF I and CF II are thought to be released, whereas CPSF and poly(A) polymerase remain to carry out polyadenylation.&#xD;
</Comment>
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  </Label>
  <Label TextLabel="Additional Factors" GraphId="dbd">
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  </Label>
  <Label TextLabel="Alternative Splicing" GraphId="dc2">
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  </Label>
  <Label TextLabel="Formation of the Spliceosomal C complex" GraphId="dd7">
    <Comment Source="GenMAPP remarks">The spliceosomal C complex is a very short-lived intermediate; the splicing intermediates are rapidly converted to splicing products. Also, the spliced products are released very rapidly, and no complex containing both the splicing products has been isolated. Conversion of the spliceosomal B complex to the spliceosomal C complex requires ATP. The extensive base-pairing between the U4 and U6 snRNAs is disrupted during the formation of the C complex, which is thought to require helicase-type activity associated with the DEAD box factors. Krainer, A, 2003-06-05</Comment>
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  </Label>
  <Label TextLabel="5" GraphId="dda">
    <Graphics CenterX="80.0" CenterY="420.0" Width="12.333333333333334" Height="15.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="9" Valign="Middle" />
  </Label>
  <Label TextLabel="exon 2" GraphId="de1">
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  </Label>
  <Label TextLabel="CF II" GraphId="df8">
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  </Label>
  <Label TextLabel="5" GraphId="e02">
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  <Label TextLabel="U4" GraphId="e28">
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  <Label TextLabel="Cleavage at the 3â-Splice-Site and Exon Ligation" GraphId="e39">
    <Comment Source="GenMAPP remarks">The second step of the splicing reaction results in cleavage of the transcript at the 3âsplice site, and results in ligation of the two exons and excision of the intron. Krainer, A, 2003-06-05</Comment>
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  <Label TextLabel="exon 2" GraphId="e3f">
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  <Label TextLabel="YYYY" GraphId="e40">
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  <Label TextLabel="5" GraphId="e57">
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  <Label TextLabel="YYYY" GraphId="e65">
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  <Label TextLabel="U5" GraphId="e66">
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  <Label TextLabel="exon 2" GraphId="e6d">
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  <Label TextLabel="U4/U6" GraphId="e73">
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  <Label TextLabel="U2AF" GraphId="e86">
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  <Label TextLabel="SR-phosphatases" GraphId="e89">
    <Comment Source="GenMAPP remarks">Phosphorylates RS domains</Comment>
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  <Label TextLabel="Internal methylation of mRNA" GraphId="e8c">
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  <Label TextLabel="Poly(A) pol" GraphId="ea3">
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  <Label TextLabel="AG" GraphId="ea5">
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  <Label TextLabel="U6" GraphId="eb3">
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  <Label TextLabel="exon 2" GraphId="eb4">
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  <Label TextLabel="Methylation of mRNA" GraphId="ebd">
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  <Label TextLabel="AG" GraphId="ebf">
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  <Label TextLabel="GU" GraphId="ec0">
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  <Label TextLabel="(2)" GraphId="ec3">
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  <Label TextLabel="AG" GraphId="ec8">
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  <Label TextLabel="U1 snRNP" GraphId="ecc">
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  <Label TextLabel="U1 snRNP" GraphId="edd">
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  <Label TextLabel="pre-mRNA" GraphId="ee0">
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  <Label TextLabel="A" GraphId="ee2">
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  <Label TextLabel="SR protein phosphatases" GraphId="f09">
    <Comment Source="GenMAPP remarks">Clk proteins can interact with and phosphorylate SR proteins.  These proteins are capable of autophosphorylation and may alter the subnuclear localization of SR proteins. While the Clk proteins phosphorylate RS domains, they themselves contain RS-like domains and are also known to be autophosphorylated on tyrosines.</Comment>
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  <Label TextLabel="Kinases Phosphorylating RS domains?" GraphId="f0f">
    <Comment Source="GenMAPP remarks">RS dipeptides</Comment>
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  <Label TextLabel="splicesome associated helicases" GraphId="f14">
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  <Label TextLabel="Processing of Intron-Containing Pre-mRNA" GraphId="f17">
    <Comment Source="GenMAPP remarks">Any covalent change in a primary (nascent) mRNA transcript is mRNA Processing. For successful gene expression, the primary mRNA transcript needs to be converted to a mature mRNA prior to its translation into polypeptide. Eucaryotic mRNAs undergo a series of complex processing reactions; these begin on nascent transcripts as soon as a few ribonucleotides have been synthesized during transcription by RNA Polymerase II, through the export of the mature mRNA to the cytoplasm, and culminate with mRNA turnover in the cytoplasm. Carmichael, GG, Hammarskjold, ML, Hastings, M, Krainer, A, Marzluff, WF, 2003-06-05</Comment>
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  <Label TextLabel="5" GraphId="f23">
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  <Label TextLabel="exon 1" GraphId="f25">
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  <Label TextLabel="Formation of the Spliceosomal A complex" GraphId="f2d">
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  <Label TextLabel="U5" GraphId="f30">
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  <Label TextLabel="U1" GraphId="f35">
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  <Label TextLabel="A" GraphId="f36">
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  <Label TextLabel="YYYY" GraphId="f37">
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  <Label TextLabel="U4:U5:U6 tri-snRNP complex" GraphId="f3c">
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  <Label TextLabel="AG" GraphId="f42">
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  <Label TextLabel="3" GraphId="f48">
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  <Label TextLabel="U2 snRNP" GraphId="f4e">
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  <Label TextLabel="Pi" GraphId="f50">
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  <Label TextLabel="mRNA Capping" GraphId="f5a">
    <Comment Source="GenMAPP remarks">The 5â-ends of all eukaryotic pre-mRNAs studied thus far are converted to cap structures. The cap is thought to influence splicing of the first intron, and is bound by âcap-bindingâ proteins, CBP80 and CBP20, in the nucleus. The cap is important for translation initiation, and it also interacts with the poly(A)terminus, via proteins, resulting in circularization of the mRNA to facilitate multiple rounds of translation. The cap is also important for mRNA stability, protecting it from 5â to 3â nucleases, and is required for mRNA export to the cytoplasm.&#xD;
The capping reaction usually occurs very rapidly on nascent transcripts; after the synthesis of only a few nucleotides by RNA polymerase II. The capping reaction involves the conversion of the 5â-end of the nascent transcript from a triphosphate to a diphosphate by a RNA 5â-triphosphatase, followed by the addition of a guanosine monophosphate by the mRNA guanylyltransferase, to form a 5â-5â-triphosphate linkage. This cap is then methylated by 2â-O-methyltransferases. Buratowski, S, 2003-10-15</Comment>
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  <Label TextLabel="Formation of the Spliceosomal E complex" GraphId="f5d">
    <Comment Source="GenMAPP remarks">Pre-mRNA transcripts become rapidly associated with many RNA-binding proteins, including hnRNP proteins, cap-binding proteins, SR proteins, etc; in the test tube this binding does not require splice sites or ATP. The E complex, or early complex, is the first detectable functional intermediate in spliceosome assembly in vitro. It is an ATP-independent complex. When a functional 5? splice site is present, it is bound by the U1 snRNP. The splicing factor U2AF (65 and 35 kDa subunits) binds to the polypyrimidine tract (Y)n and the AG dinucleotide at the 3â splice site, respectively. SF1/mBBP binds to the branch site. Binding of many of these factors is cooperative; e.g., SR proteins and U2AF apparently interact with each other, facilitating their binding to the pre-mRNA.In the presence of ATP, the E complex is converted to the first ATP-dependent spliceosomal complex, namely the A complex. Krainer, A, 2003-06-05</Comment>
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  <Label TextLabel="UG" GraphId="f7e">
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  <Label TextLabel="Formation of the Spliceosomal E complex" GraphId="f8d">
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  <Label TextLabel="Lariat Formation and 5â-Splice Site Cleavage" GraphId="fa6">
    <Comment Source="GenMAPP remarks">In the first catalytic step of mRNA splicing, the 2â OH group of the bulged A at the branch site performs a nucleophilic attack on the 5â splice site phosphodiester bond, resulting in cleavage of the bond between the 5â exon and the 5â end of the intron, and formation of a new bond between the 5â end of the intron and the branch site A. This results in a lariat-shaped intermediate, with the intron still attached to the 3â exon. The branch site A has a 2â-5â phosphodiester bond with the G at the beginning of the intron, in addition to the usual 5â-3â and 3â-5âphosphodiester bonds.  Krainer, A, 2003-06-05</Comment>
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  <Label TextLabel="(3)" GraphId="faa">
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  <Label TextLabel="snRNP Sm core complex" GraphId="fb7">
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  <Label TextLabel="degraded" GraphId="fc6">
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  <Label TextLabel="Note: New participating members shown at each step" GraphId="fce">
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  <Label TextLabel="Putative Alternative Splicing" GraphId="fd7">
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  <Label TextLabel="GMP" GraphId="fe1">
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  <Label TextLabel="Formation of the Spliceosomal A complex" GraphId="fe5">
    <Comment Source="GenMAPP remarks">The A complex is the first ATP-dependent complex in spliceosome assembly. U2AF recruits the U2 snRNP to bind to the branch site in the E complex in an ATP-dependent fashion, to form the A complex. The U2 snRNA base-pairs with the branch site, causing the branch-site adenosine to bulge out, which later positions it for nucleophillic attack at the 5â splice site. The A complex serves as a substrate for formation of the B complex. Krainer, A, 2003-06-05</Comment>
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  <Label TextLabel="RNA-binding region RNP-1  (RNA recognition motif)" GraphId="fe6">
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  <Label TextLabel="Cap Binding" GraphId="fed">
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  <Label TextLabel="SF3b14b" GraphId="ffa">
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  <Label TextLabel="mRNA 3â-end processing" GraphId="ffe">
    <Comment Source="GenMAPP remarks">The 3â ends of eukaryotic mRNAs are generated by posttranscriptional processing of an extended primary transcript. For almost all RNAs, 3â-end processing consists of two steps: (i) the mRNA is first cleaved at a particular phosphodiester bond downstream of the coding sequence, (ii) the upstream fragment then receives a poly(A) tail of approximately 250 adenylate residues, whereas the downstream fragment is degraded. The two partial reactions are coupled so that reaction intermediates are usually undetectable. While 3â processing can be studied as an isolated event in vitro, it appears to be connected to transcription, splicing, and transcription termination in vivo.&#xD;
The only known exception to the rule of cleavage followed by polyadenylation are the major histone mRNAs, which are cleaved but not polyadenylated.&#xD;
</Comment>
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