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<Pathway xmlns="http://pathvisio.org/GPML/2013a" Name="MicroRNAs in cardiomyocyte hypertrophy" Data-Source="WikiPathways" Version="WP1560_r116839" Author="[MaintBot, MLevels, Ddigles, AlexanderPico, Laurent, Eweitz]" Last-Modified="20210514103115" Organism="Mus musculus">
  <Comment Source="WikiPathways-description">This pathway shows the role of microRNAs in the process of cardiac hypertrophy.
Converted from the humane pathway.
MicroRNA targets were predicted by the TargetScan algorithm, and the predicted interactions are shown in red, dashed lines.
MicroRNAs are shown as purple rounded rectangles.
It is not sure which WNT and frizzled proteins influence cardiac hypertrophy. Though there are strong indications that WNT3A, WNT5A, frizzled1 and frizzled2 play a role in cardiac hypertrophy. Thus these have been added to the pathway instead of all the WNT and frizzled proteins. Experiments which will shed light on this are still being done.</Comment>
  <Comment Source="HomologyConvert">This pathway was inferred from Homo sapiens pathway [http://www.wikipathways.org/index.php?title=Pathway:WP1544&amp;oldid=37553 WP1544(r37553)] with a 96% conversion rate.</Comment>
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