<?xml version="1.0" encoding="UTF-8"?>
<Pathway xmlns="http://pathvisio.org/GPML/2013a" Name="Iron homeostasis" Data-Source="WikiPathways" Version="WP1596_r142309" Author="[MartijnVanIersel, Khanspers, MaintBot, Samuel Sklar, Egonw, Ddigles, Mkutmon, Eweitz]" Last-Modified="20260101105346" Organism="Mus musculus">
  <Comment Source="WikiPathways-description">Iron is nessisary for all mammalian cells but is also toxic in excess. This pathway shows the regulation of iron between a cell and the blood stream.</Comment>
  <Graphics BoardWidth="678.0" BoardHeight="561.0" />
  <DataNode TextLabel="Transferrin" GraphId="a0d8b" Type="GeneProduct">
    <Graphics CenterX="485.0" CenterY="156.0" Width="80.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Ensembl" ID="ENSMUSG00000032554" />
  </DataNode>
  <DataNode TextLabel="Fth1" GraphId="a6d1e" Type="GeneProduct" GroupRef="fe4e0">
    <Graphics CenterX="237.0" CenterY="118.0" Width="80.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="14319" />
  </DataNode>
  <DataNode TextLabel="Trfr2" GraphId="af3ce" Type="GeneProduct">
    <Graphics CenterX="360.5" CenterY="311.0" Width="85.0" Height="20.000000000000014" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Ensembl" ID="ENSMUSG00000029716" />
  </DataNode>
  <DataNode TextLabel="Trfr1" GraphId="b12e8" Type="GeneProduct">
    <Graphics CenterX="359.3131553860821" CenterY="285.0" Width="85.0" Height="22.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="" ID="" />
  </DataNode>
  <DataNode TextLabel="Ftl1" GraphId="b1b08" Type="GeneProduct" GroupRef="fe4e0">
    <Graphics CenterX="237.0" CenterY="98.0" Width="80.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Ensembl" ID="ENSMUSG00000050708" />
  </DataNode>
  <DataNode TextLabel="hepcidin-2" GraphId="b926a" Type="GeneProduct">
    <Graphics CenterX="535.0" CenterY="311.0" Width="80.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Ensembl" ID="ENSMUSG00000056978" />
  </DataNode>
  <DataNode TextLabel="Ireb2" GraphId="ba42e" Type="GeneProduct">
    <Graphics CenterX="135.0" CenterY="193.0" Width="80.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Ensembl" ID="ENSMUSG00000032293" />
  </DataNode>
  <DataNode TextLabel="hepcidin" GraphId="bb6fd" Type="GeneProduct">
    <Graphics CenterX="535.0" CenterY="331.0" Width="80.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Ensembl" ID="ENSMUSG00000050440" />
  </DataNode>
  <DataNode TextLabel="STAT3" GraphId="c3b0c" Type="GeneProduct">
    <Graphics CenterX="214.0" CenterY="380.0" Width="80.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="" ID="" />
  </DataNode>
  <DataNode TextLabel="IL1R" GraphId="c9a17" Type="GeneProduct">
    <Graphics CenterX="365.0" CenterY="372.0" Width="85.0" Height="20.000000000000014" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="" ID="" />
  </DataNode>
  <DataNode TextLabel="Tnf" GraphId="ce64e" Type="GeneProduct">
    <Graphics CenterX="79.0" CenterY="130.0" Width="80.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Ensembl" ID="ENSMUSG00000024401" />
  </DataNode>
  <DataNode TextLabel="JAK1/2" GraphId="d1d51" Type="GeneProduct">
    <Graphics CenterX="266.0" CenterY="418.0" Width="80.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="" ID="" />
  </DataNode>
  <DataNode TextLabel="SMAD-1/5/8" GraphId="d488e" Type="GeneProduct">
    <Graphics CenterX="140.0" CenterY="427.0" Width="80.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="" ID="" />
  </DataNode>
  <DataNode TextLabel="IL-6" GraphId="d5d8e" Type="GeneProduct">
    <Graphics CenterX="487.0" CenterY="407.0" Width="80.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Ensembl" ID="ENSMUSG00000025746" />
  </DataNode>
  <DataNode TextLabel="Iron" GraphId="d792a" Type="Metabolite">
    <Graphics CenterX="241.0" CenterY="228.0" Width="80.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="HMDB" ID="HMDB0000692" />
  </DataNode>
  <DataNode TextLabel="BMPR-1" GraphId="d7a54" Type="GeneProduct">
    <Graphics CenterX="365.0" CenterY="496.0" Width="85.0" Height="20.000000000000014" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="" ID="" />
  </DataNode>
  <DataNode TextLabel="hemojuvelin" GraphId="dfb51" Type="GeneProduct">
    <Graphics CenterX="486.99999999999994" CenterY="521.0" Width="80.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Ensembl" ID="ENSMUSG00000038403" />
  </DataNode>
  <DataNode TextLabel="Iron" GraphId="e6e40" Type="Metabolite">
    <Graphics CenterX="484.0" CenterY="225.0" Width="80.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="HMDB" ID="HMDB0000692" />
  </DataNode>
  <DataNode TextLabel="BMP1/2/4/9" GraphId="efe7c" Type="GeneProduct">
    <Graphics CenterX="486.99999999999994" CenterY="466.0" Width="80.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="" ID="" />
  </DataNode>
  <DataNode TextLabel="cMyc" GraphId="f1796" Type="GeneProduct">
    <Graphics CenterX="80.0" CenterY="85.0" Width="80.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="" ID="" />
  </DataNode>
  <DataNode TextLabel="Hfe" GraphId="f33e8" Type="GeneProduct">
    <Graphics CenterX="196.0" CenterY="286.0" Width="80.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Ensembl" ID="ENSMUSG00000006611" />
  </DataNode>
  <DataNode TextLabel="IL6R" GraphId="f3770" Type="GeneProduct">
    <Graphics CenterX="365.00000000000006" CenterY="403.0" Width="85.0" Height="20.000000000000014" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Ensembl" ID="ENSMUSG00000027947" />
  </DataNode>
  <DataNode TextLabel="hepcidin-2" GraphId="f5bac" Type="GeneProduct">
    <Graphics CenterX="77.0" CenterY="314.0" Width="80.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Ensembl" ID="ENSMUSG00000056978" />
  </DataNode>
  <DataNode TextLabel="hepcidin" GraphId="f710c" Type="GeneProduct">
    <Graphics CenterX="77.0" CenterY="334.0" Width="80.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Ensembl" ID="ENSMUSG00000050440" />
  </DataNode>
  <DataNode TextLabel="Ferroportin" GraphId="fb03f" Type="GeneProduct">
    <Graphics CenterX="355.5" CenterY="138.0" Width="85.0" Height="19.999999999999986" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Ensembl" ID="ENSMUSG00000025993" />
  </DataNode>
  <DataNode TextLabel="IL-1" GraphId="fc39a" Type="GeneProduct">
    <Graphics CenterX="487.0" CenterY="367.0" Width="80.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Ensembl" ID="ENSMUSG00000027399" />
  </DataNode>
  <Interaction GraphId="a2215">
    <Graphics ZOrder="12288" LineThickness="1.0">
      <Point X="398.0" Y="138.0" GraphRef="fb03f" RelX="1.0" RelY="0.0" />
      <Point X="425.0" Y="198.0" GraphRef="e0b16" RelX="0.0" RelY="0.0" ArrowHead="mim-stimulation" />
    </Graphics>
    <Xref Database="" ID="" />
  </Interaction>
  <Interaction GraphId="ab5c5">
    <Graphics ZOrder="12288" LineThickness="1.0">
      <Point X="119.0" Y="130.0" GraphRef="ce64e" RelX="1.0" RelY="0.0" />
      <Point X="185.0" Y="108.0" GraphRef="d1b0c" RelX="-1.0" RelY="0.0" ArrowHead="Arrow" />
    </Graphics>
    <Xref Database="" ID="" />
  </Interaction>
  <Interaction GraphId="c3d89">
    <Graphics ZOrder="12288" LineThickness="1.0">
      <Point X="447.0" Y="407.0" GraphRef="d5d8e" RelX="-1.0" RelY="0.0" />
      <Point X="407.50000000000006" Y="403.0" GraphRef="f3770" RelX="1.0" RelY="0.0" ArrowHead="Arrow" />
    </Graphics>
    <Xref Database="" ID="" />
  </Interaction>
  <Interaction GraphId="ec128">
    <Graphics ZOrder="12288" LineThickness="1.0">
      <Point X="237.0" Y="140.0" GraphRef="d1b0c" RelX="0.0" RelY="1.0" ArrowHead="mim-binding" />
      <Point X="241.0" Y="218.0" GraphRef="d792a" RelX="0.0" RelY="-1.0" ArrowHead="mim-binding" />
      <Anchor Position="0.44155844155844154" Shape="Circle" />
    </Graphics>
    <Xref Database="" ID="" />
  </Interaction>
  <Interaction GraphId="id1334398d">
    <Graphics ZOrder="12288" LineThickness="1.0">
      <Point X="322.5" Y="372.0" GraphRef="c9a17" RelX="-1.0" RelY="0.0" />
      <Point X="117.0" Y="334.0" GraphRef="f710c" RelX="1.0" RelY="0.0" ArrowHead="Arrow" />
    </Graphics>
    <Xref Database="" ID="" />
  </Interaction>
  <Interaction GraphId="id1770c409">
    <Graphics ZOrder="12288" LineThickness="1.0">
      <Point X="322.5" Y="496.0" GraphRef="d7a54" RelX="-1.0" RelY="0.0" />
      <Point X="180.0" Y="427.0" GraphRef="d488e" RelX="1.0" RelY="0.0" ArrowHead="Arrow" />
    </Graphics>
    <Xref Database="" ID="" />
  </Interaction>
  <Interaction GraphId="id1b72726a">
    <Graphics ConnectorType="Elbow" ZOrder="12288" LineThickness="1.0">
      <Point X="318.0" Y="311.0" GraphRef="af3ce" RelX="-1.0" RelY="0.0" />
      <Point X="279.0" Y="298.5" />
      <Point X="236.0" Y="286.0" GraphRef="f33e8" RelX="1.0" RelY="0.0" ArrowHead="Arrow" />
    </Graphics>
    <Xref Database="" ID="" />
  </Interaction>
  <Interaction GraphId="id1db6a281">
    <Graphics ZOrder="12288" LineThickness="1.0">
      <Point X="196.0" Y="296.0" GraphRef="f33e8" RelX="0.0" RelY="1.0" />
      <Point X="117.0" Y="334.0" GraphRef="f710c" RelX="1.0" RelY="0.0" ArrowHead="Arrow" />
    </Graphics>
    <Xref Database="" ID="" />
  </Interaction>
  <Interaction GraphId="id2c47fde1">
    <Graphics ConnectorType="Elbow" ZOrder="12288" LineThickness="1.0">
      <Point X="316.8131553860821" Y="285.0" GraphRef="b12e8" RelX="-1.0" RelY="0.0" />
      <Point X="279.0" Y="285.5" />
      <Point X="236.0" Y="286.0" GraphRef="f33e8" RelX="1.0" RelY="0.0" ArrowHead="Arrow" />
    </Graphics>
    <Xref Database="" ID="" />
  </Interaction>
  <Interaction GraphId="id30536691">
    <Graphics ZOrder="12288" LineThickness="1.0">
      <Point X="120.0" Y="85.0" GraphRef="f1796" RelX="1.0" RelY="0.0" />
      <Point X="185.0" Y="108.0" GraphRef="d1b0c" RelX="-1.0" RelY="0.0" ArrowHead="Arrow" />
    </Graphics>
    <Xref Database="" ID="" />
  </Interaction>
  <Interaction GraphId="id355431fb">
    <Graphics ZOrder="12288" LineThickness="1.0">
      <Point X="568.0" Y="379.0" GraphRef="e4dbb" RelX="-1.0" RelY="0.0" />
      <Point X="527.0" Y="367.0" GraphRef="fc39a" RelX="1.0" RelY="0.0" ArrowHead="Arrow" />
    </Graphics>
    <Xref Database="" ID="" />
  </Interaction>
  <Interaction GraphId="id380d6a8b">
    <Graphics ZOrder="12288" LineThickness="1.0">
      <Point X="515.0" Y="321.0" GraphRef="bb6fd" RelX="-0.5" RelY="-1.0" />
      <Point X="376.75" Y="148.0" GraphRef="fb03f" RelX="0.5" RelY="1.0" ArrowHead="TBar" />
    </Graphics>
    <Xref Database="" ID="" />
  </Interaction>
  <Interaction GraphId="id47922eae">
    <BiopaxRef>a07</BiopaxRef>
    <Graphics ZOrder="12288" LineThickness="1.0">
      <Point X="135.0" Y="183.0" GraphRef="ba42e" RelX="0.0" RelY="-1.0" />
      <Point X="211.0" Y="140.0" GraphRef="d1b0c" RelX="-0.5" RelY="1.0" ArrowHead="Arrow" />
    </Graphics>
    <Xref Database="" ID="" />
  </Interaction>
  <Interaction GraphId="id4d5f8009">
    <Graphics ZOrder="12288" LineThickness="1.0">
      <Point X="403.0" Y="311.0" GraphRef="af3ce" RelX="1.0" RelY="0.0" />
      <Point X="417.8889823276556" Y="262.2370630438101" GraphRef="d7a4c" RelX="0.0" RelY="0.0" />
    </Graphics>
    <Xref Database="" ID="" />
  </Interaction>
  <Interaction GraphId="id5af2b362">
    <Graphics ZOrder="12288" LineThickness="1.0">
      <Point X="194.0" Y="370.0" GraphRef="c3b0c" RelX="-0.5" RelY="-1.0" />
      <Point X="97.0" Y="344.0" GraphRef="f710c" RelX="0.5" RelY="1.0" ArrowHead="Arrow" />
    </Graphics>
    <Xref Database="" ID="" />
  </Interaction>
  <Interaction GraphId="id5c10042">
    <Graphics ZOrder="12288" LineThickness="1.0">
      <Point X="568.0" Y="379.0" GraphRef="e4dbb" RelX="-1.0" RelY="0.0" />
      <Point X="527.0" Y="407.0" GraphRef="d5d8e" RelX="1.0" RelY="0.0" ArrowHead="Arrow" />
    </Graphics>
    <Xref Database="" ID="" />
  </Interaction>
  <Interaction GraphId="id748d82f">
    <Graphics ConnectorType="Elbow" ZOrder="12288" LineThickness="1.0">
      <Point X="261.0" Y="218.0" GraphRef="d792a" RelX="0.5" RelY="-1.0" />
      <Point X="464.0" Y="215.0" GraphRef="e6e40" RelX="-0.5" RelY="-1.0" />
      <Anchor Position="0.7666666666666667" Shape="None" GraphId="e0b16" />
    </Graphics>
    <Xref Database="" ID="" />
  </Interaction>
  <Interaction GraphId="id80b9fe26">
    <Graphics ZOrder="12288" LineThickness="1.0">
      <Point X="447.0" Y="466.0" GraphRef="efe7c" RelX="-1.0" RelY="0.0" />
      <Point X="407.5" Y="496.0" GraphRef="d7a54" RelX="1.0" RelY="0.0" ArrowHead="Arrow" />
    </Graphics>
    <Xref Database="" ID="" />
  </Interaction>
  <Interaction GraphId="id84841d50">
    <Graphics ZOrder="12288" LineThickness="1.0">
      <Point X="447.0" Y="521.0" GraphRef="dfb51" RelX="-1.0" RelY="0.0" />
      <Point X="407.5" Y="496.0" GraphRef="d7a54" RelX="1.0" RelY="0.0" ArrowHead="Arrow" />
    </Graphics>
    <Xref Database="" ID="" />
  </Interaction>
  <Interaction GraphId="id8d8f984a">
    <Graphics ZOrder="12288" LineThickness="1.0">
      <Point X="246.0" Y="408.0" GraphRef="d1d51" RelX="-0.5" RelY="-1.0" />
      <Point X="234.0" Y="390.0" GraphRef="c3b0c" RelX="0.5" RelY="1.0" ArrowHead="Arrow" />
    </Graphics>
    <Xref Database="" ID="" />
  </Interaction>
  <Interaction GraphId="id988524b3">
    <Graphics ConnectorType="Elbow" ZOrder="12288" LineThickness="1.0">
      <Point X="464.0" Y="235.0" GraphRef="e6e40" RelX="-0.5" RelY="1.0" />
      <Point X="261.0" Y="238.0" GraphRef="d792a" RelX="0.5" RelY="1.0" />
      <Anchor Position="0.25416666666666665" Shape="None" GraphId="fdbaa" />
    </Graphics>
    <Xref Database="" ID="" />
  </Interaction>
  <Interaction GraphId="id9a5e6429">
    <Graphics ZOrder="12288" LineThickness="1.0">
      <Point X="322.50000000000006" Y="403.0" GraphRef="f3770" RelX="-1.0" RelY="0.0" />
      <Point X="306.0" Y="418.0" GraphRef="d1d51" RelX="1.0" RelY="0.0" ArrowHead="Arrow" />
    </Graphics>
    <Xref Database="" ID="" />
  </Interaction>
  <Interaction GraphId="idb678f24b">
    <Graphics ZOrder="12288" LineThickness="1.0">
      <Point X="485.0" Y="166.0" GraphRef="a0d8b" RelX="0.0" RelY="1.0" ArrowHead="mim-binding" />
      <Point X="484.0" Y="215.0" GraphRef="e6e40" RelX="0.0" RelY="-1.0" ArrowHead="mim-binding" />
      <Anchor Position="0.44155844155844154" Shape="Circle" />
    </Graphics>
    <Xref Database="" ID="" />
  </Interaction>
  <Interaction GraphId="idc4e22227">
    <Graphics ZOrder="12288" LineThickness="1.0">
      <Point X="447.0" Y="367.0" GraphRef="fc39a" RelX="-1.0" RelY="0.0" />
      <Point X="407.5" Y="372.0" GraphRef="c9a17" RelX="1.0" RelY="0.0" ArrowHead="Arrow" />
    </Graphics>
    <Xref Database="" ID="" />
  </Interaction>
  <Interaction GraphId="idcf4701b4">
    <Graphics ZOrder="12288" LineThickness="1.0">
      <Point X="117.0" Y="334.0" GraphRef="f710c" RelX="1.0" RelY="0.0" />
      <Point X="495.0" Y="331.0" GraphRef="bb6fd" RelX="-1.0" RelY="0.0" />
    </Graphics>
    <Xref Database="" ID="" />
  </Interaction>
  <Interaction GraphId="idd5c2fb37">
    <Graphics ZOrder="12288" LineThickness="1.0">
      <Point X="100.0" Y="109.0" GraphRef="f04ec" RelX="1.0" RelY="0.0" />
      <Point X="185.0" Y="108.0" GraphRef="d1b0c" RelX="-1.0" RelY="0.0" ArrowHead="Arrow" />
    </Graphics>
    <Xref Database="" ID="" />
  </Interaction>
  <Interaction GraphId="idd7dc36a2">
    <Graphics ZOrder="12288" LineThickness="1.0">
      <Point X="140.0" Y="417.0" GraphRef="d488e" RelX="0.0" RelY="-1.0" />
      <Point X="77.0" Y="344.0" GraphRef="f710c" RelX="0.0" RelY="1.0" ArrowHead="Arrow" />
    </Graphics>
    <Xref Database="" ID="" />
  </Interaction>
  <Interaction GraphId="ide51745fb">
    <Graphics ZOrder="12288" LineThickness="1.0">
      <Point X="401.8131553860821" Y="285.0" GraphRef="b12e8" RelX="1.0" RelY="0.0" />
      <Point X="423.0" Y="255.0" GraphRef="fdbaa" RelX="0.0" RelY="0.0" ArrowHead="mim-stimulation" />
      <Anchor Position="0.75876456520633" Shape="None" GraphId="d7a4c" />
    </Graphics>
    <Xref Database="" ID="" />
  </Interaction>
  <Label TextLabel="Cell" GraphId="d4dd9">
    <Graphics CenterX="327.011011011011" CenterY="82.05205205205203" Width="80.0" Height="20.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="10" Valign="Middle" Color="ff0000" />
  </Label>
  <Label TextLabel="Blood" GraphId="dfbe0">
    <Graphics CenterX="409.22678254994725" CenterY="81.10276720953554" Width="80.0" Height="20.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="10" Valign="Middle" Color="ff0000" />
  </Label>
  <Label TextLabel="Inflammation" GraphId="e4dbb">
    <Graphics CenterX="608.0" CenterY="379.0" Width="80.0" Height="20.0" ZOrder="28672" FillColor="ffffff" FontSize="10" Valign="Middle" />
  </Label>
  <Label TextLabel="Oxidative Stress" GraphId="f04ec">
    <Graphics CenterX="60.0" CenterY="109.0" Width="80.0" Height="20.0" ZOrder="28672" FillColor="ffffff" FontSize="10" Valign="Middle" />
  </Label>
  <Shape GraphId="aa47d">
    <Attribute Key="org.pathvisio.CellularComponentProperty" Value="Cell" />
    <Attribute Key="org.pathvisio.DoubleLineProperty" Value="Double" />
    <Graphics CenterX="194.03885852233367" CenterY="287.6629489544684" Width="351.67442785523724" Height="458.1330935251797" ZOrder="16384" FontSize="10" Valign="Middle" ShapeType="RoundedRectangle" LineThickness="3.0" Color="c0c0c0" Rotation="0.0" />
  </Shape>
  <Group GroupId="fe4e0" GraphId="d1b0c" Style="Complex" />
  <InfoBox CenterX="0.0" CenterY="0.0" />
  <Biopax>
    <bp:openControlledVocabulary xmlns:bp="http://www.biopax.org/release/biopax-level3.owl#">
      <bp:TERM xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" rdf:datatype="http://www.w3.org/2001/XMLSchema#string">iron homeostasis pathway</bp:TERM>
      <bp:ID xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" rdf:datatype="http://www.w3.org/2001/XMLSchema#string">PW:0000590</bp:ID>
      <bp:Ontology xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Pathway Ontology</bp:Ontology>
    </bp:openControlledVocabulary>
  </Biopax>
</Pathway>

