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<Pathway xmlns="http://pathvisio.org/GPML/2013a" Name="Glycolysis and gluconeogenesis" Data-Source="WikiPathways" Version="WP157_r137229" Author="[Kdahlquist, MaintBot, M.Braymer, MartijnVanIersel, AdrienDefay, Thomas, Christine Chichester, Egonw, Liisa18, AlexanderPico, Gharding, Mkutmon, Eweitz]" Last-Modified="20250301100741" Organism="Mus musculus">
  <Comment Source="WikiPathways-description">Glycolysis is the metabolic pathway that converts glucose C6H12O6, into pyruvate, CH3COCOOâˆ’ + H+. The free energy released in this process is used to form the ATP and NADH.
Gluconeogenesis is a metabolic pathway that results in the generation of glucose from non-carbohydrate carbon substrates such as pyruvate, lactate, glycerol, glucogenic amino acids, and fatty acids.
Description adapted from [Wikipedia](http://www.wikipedia.org).</Comment>
  <Comment Source="HomologyConvert">This pathway was inferred from Homo sapiens pathway [http://www.wikipathways.org/index.php?title=Pathway:WP534&amp;amp;amp;amp;oldid=28564 WP534(r28564)] with a 76% conversion rate.</Comment>
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    <Comment>Gck is mainly active in liver</Comment>
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    <Comment>Not present in brain and muscle, so those organs can not produce their own glucose in the gluconeogenesis pathway</Comment>
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