<?xml version="1.0" encoding="UTF-8"?>
<Pathway xmlns="http://pathvisio.org/GPML/2013a" Name="Purine metabolism" Data-Source="WikiPathways" Version="WP2185_r140895" Author="[Qiuying, MaintBot, Egonw, Jmelius, DeSl, Maxvanson, Fehrhart, Shi, AlexanderPico, Larsgw]" Last-Modified="20251030073826" Organism="Mus musculus">
  <Comment Source="WikiPathways-description">Purine nucleotides can be synthesised de novo, or can be reclaimed from existing nucleosides in the pyrimide biosynthesis pathway. The de novo pathway need 1-carbon units from the folate pool, and several other amino acids, such as aspartate and glutamine.</Comment>
  <BiopaxRef>aa8</BiopaxRef>
  <Attribute Key="ConversionDate" Value="20110526" />
  <Attribute Key="KeggId" Value="path:mmu00230" />
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    <Xref Database="Ensembl" ID="ENSMUSG00000078941" />
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  <DataNode TextLabel="Enpp1" GraphId="f3722" Type="GeneProduct" GroupRef="ff9d5">
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  <DataNode TextLabel="Nudt16" GraphId="cabfe" Type="GeneProduct" GroupRef="e4b1d">
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  <DataNode TextLabel="Enpp3" GraphId="e0756" Type="GeneProduct" GroupRef="ff9d5">
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    <Xref Database="Ensembl" ID="ENSMUSG00000019989" />
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  <DataNode TextLabel="Ak9" GraphId="b8046" Type="GeneProduct" GroupRef="b11a0">
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  <DataNode TextLabel="1700080E11Rik" GraphId="ed335" Type="GeneProduct" GroupRef="e4b1d">
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    <Xref Database="Ensembl" ID="ENSMUSG00000032566" />
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  <DataNode TextLabel="Tseg8" GraphId="be437" Type="GeneProduct" GroupRef="afe80">
    <Graphics CenterX="1827.7597402597403" CenterY="521.8144214542523" Width="80.00000000000007" Height="20.000000000000018" ZOrder="33906" FontSize="12" Valign="Middle" />
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  <DataNode TextLabel="Ak3" GraphId="da58b" Type="GeneProduct">
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  <DataNode TextLabel="Nudt16" GraphId="c69a3" Type="GeneProduct" GroupRef="afe80">
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  <DataNode TextLabel="Ak8" GraphId="c7c94" Type="GeneProduct" GroupRef="b11a0">
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  <DataNode TextLabel="Entpd3" GraphId="bc48f" Type="GeneProduct" GroupRef="c6c79">
    <Comment Source="KeggConverter">Original kegg element: gene;197;mmu:12495 mmu:215446 mmu:72090</Comment>
    <Graphics CenterX="1937.956709956711" CenterY="501.54831609068845" Width="80.0" Height="20.0" ZOrder="34122" FontSize="10" Valign="Middle" />
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  <DataNode TextLabel="Pklr" GraphId="d1dd1" Type="GeneProduct" GroupRef="ceecb">
    <Comment Source="KeggConverter">Original kegg element: gene;311;mmu:18746 mmu:18770</Comment>
    <Graphics CenterX="2932.947368421054" CenterY="870.1730597680637" Width="80.0" Height="20.0" ZOrder="34123" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="18770" />
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  <DataNode TextLabel="deoxyinosine" GraphId="b5879" Type="Metabolite">
    <Graphics CenterX="3110.0" CenterY="1294.0677966101696" Width="80.0" Height="20.0" ZOrder="34124" FontSize="10" Valign="Middle" Color="0000ff" />
    <Xref Database="KEGG Compound" ID="C05512" />
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  <DataNode TextLabel="Pde1a" GraphId="c0c45" Type="GeneProduct" GroupRef="f5806">
    <Comment Source="KeggConverter">Original kegg element: gene;165;mmu:110385 mmu:18573 mmu:18574 mmu:18575 mmu:18576 mmu:18577 mmu:18578 mmu:18583 mmu:18584 mmu:207728 mmu:218461 mmu:238871 mmu:23984 mmu:241489 mmu:29863 mmu:54611</Comment>
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    <Xref Database="Entrez Gene" ID="18573" />
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  <DataNode TextLabel="Fhit" GraphId="e381f" Type="GeneProduct">
    <Comment Source="KeggConverter">Original kegg element: gene;296;mmu:14198</Comment>
    <Graphics CenterX="2616.0540242557877" CenterY="637.8605198736761" Width="80.0" Height="20.0" ZOrder="34126" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="14198" />
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  <DataNode TextLabel="Pde5a" GraphId="ce046" Type="GeneProduct" GroupRef="e4165">
    <Comment Source="KeggConverter">Original kegg element: gene;245;mmu:110385 mmu:110855 mmu:18573 mmu:18574 mmu:18575 mmu:18576 mmu:18577 mmu:18578 mmu:18582 mmu:18583 mmu:18584 mmu:18585 mmu:18587 mmu:18588 mmu:207728 mmu:218461 mmu:225600 mmu:238871 mmu:23984 mmu:241489 mmu:242202 mmu:29863 mmu:54611 mmu:78600</Comment>
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    <Xref Database="Entrez Gene" ID="242202" />
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  <DataNode TextLabel="Sulfate" GraphId="c06fe" Type="Metabolite">
    <Graphics CenterX="3189.2304299889747" CenterY="192.55732251976156" Width="80.0" Height="20.0" ZOrder="34128" FontSize="10" Valign="Middle" Color="0000ff" />
    <Xref Database="KEGG Compound" ID="C00059" />
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  <DataNode TextLabel="Polr2a" GraphId="c8ddb" Type="GeneProduct" GroupRef="c746a">
    <Comment Source="KeggConverter">Original kegg element: gene;241;mmu:100043714 mmu:100046796 mmu:20016 mmu:20017 mmu:20018 mmu:20019 mmu:20020 mmu:20021 mmu:20022 mmu:218832 mmu:231329 mmu:245841 mmu:26939 mmu:625405 mmu:64424 mmu:66136 mmu:66420 mmu:66491 mmu:67005 mmu:67065 mmu:67486 mmu:67710 mmu:69241 mmu:69833 mmu:69870 mmu:69920 mmu:70408 mmu:70428 mmu:74414 mmu:78929</Comment>
    <Graphics CenterX="110.76377692730505" CenterY="1266.491691271705" Width="92.46225755421065" Height="25.554043353358804" ZOrder="34129" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="20020" />
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  <DataNode TextLabel="Nme4" GraphId="ddb03" Type="GeneProduct" GroupRef="e70b2">
    <Comment Source="KeggConverter">Original kegg element: gene;293;mmu:171567 mmu:18102 mmu:18103 mmu:54369 mmu:56520 mmu:75533 mmu:79059</Comment>
    <Graphics CenterX="931.9514884233737" CenterY="390.2728682749989" Width="80.0" Height="20.0" ZOrder="34130" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="56520" />
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  <DataNode TextLabel="Polr2f" GraphId="c82c5" Type="GeneProduct" GroupRef="afea2">
    <Comment Source="KeggConverter">Original kegg element: gene;168;mmu:100043714 mmu:100046796 mmu:20016 mmu:20017 mmu:20018 mmu:20019 mmu:20020 mmu:20021 mmu:20022 mmu:218832 mmu:231329 mmu:245841 mmu:26939 mmu:625405 mmu:64424 mmu:66136 mmu:66420 mmu:66491 mmu:67005 mmu:67065 mmu:67486 mmu:67710 mmu:69241 mmu:69833 mmu:69870 mmu:69920 mmu:70408 mmu:70428 mmu:74414 mmu:78929</Comment>
    <Graphics CenterX="3204.224130909176" CenterY="575.5776346102762" Width="90.94297214511298" Height="23.592612772064896" ZOrder="34131" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="69833" />
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  <DataNode TextLabel="Pnp2" GraphId="cb300" Type="GeneProduct" GroupRef="b805f">
    <Comment Source="KeggConverter">Original kegg element: gene;211;mmu:18950 mmu:667034</Comment>
    <Graphics CenterX="2124.2105263157887" CenterY="1086.3835860838537" Width="80.0" Height="20.0" ZOrder="34132" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="667034" />
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  <DataNode TextLabel="Pde4a" GraphId="cc490" Type="GeneProduct" GroupRef="e4165">
    <Comment Source="KeggConverter">Original kegg element: gene;245;mmu:110385 mmu:110855 mmu:18573 mmu:18574 mmu:18575 mmu:18576 mmu:18577 mmu:18578 mmu:18582 mmu:18583 mmu:18584 mmu:18585 mmu:18587 mmu:18588 mmu:207728 mmu:218461 mmu:225600 mmu:238871 mmu:23984 mmu:241489 mmu:242202 mmu:29863 mmu:54611 mmu:78600</Comment>
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    <Xref Database="Entrez Gene" ID="18577" />
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  <DataNode TextLabel="Nt5c" GraphId="d1e92" Type="GeneProduct" GroupRef="b56f8">
    <Comment Source="KeggConverter">Original kegg element: gene;192;mmu:103850 mmu:107569 mmu:230718 mmu:23959 mmu:50773 mmu:70881 mmu:76952</Comment>
    <Graphics CenterX="2104.3973483326718" CenterY="928.7660690087241" Width="80.0" Height="20.0" ZOrder="34134" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="50773" />
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  <DataNode TextLabel="Itpa" GraphId="cba54" Type="GeneProduct">
    <Comment Source="KeggConverter">Original kegg element: gene;262;mmu:16434</Comment>
    <Graphics CenterX="1136.0" CenterY="566.0677966101696" Width="80.0" Height="20.0" ZOrder="34135" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="16434" />
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  <DataNode TextLabel="Polr2c" GraphId="f9924" Type="GeneProduct" GroupRef="afea2">
    <Comment Source="KeggConverter">Original kegg element: gene;168;mmu:100043714 mmu:100046796 mmu:20016 mmu:20017 mmu:20018 mmu:20019 mmu:20020 mmu:20021 mmu:20022 mmu:218832 mmu:231329 mmu:245841 mmu:26939 mmu:625405 mmu:64424 mmu:66136 mmu:66420 mmu:66491 mmu:67005 mmu:67065 mmu:67486 mmu:67710 mmu:69241 mmu:69833 mmu:69870 mmu:69920 mmu:70408 mmu:70428 mmu:74414 mmu:78929</Comment>
    <Graphics CenterX="3295.1671030542893" CenterY="528.3924090661465" Width="90.94297214511298" Height="23.592612772064896" ZOrder="34136" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="20021" />
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  <DataNode TextLabel="Pde4c" GraphId="ab40c" Type="GeneProduct" GroupRef="f5806">
    <Comment Source="KeggConverter">Original kegg element: gene;165;mmu:110385 mmu:18573 mmu:18574 mmu:18575 mmu:18576 mmu:18577 mmu:18578 mmu:18583 mmu:18584 mmu:207728 mmu:218461 mmu:238871 mmu:23984 mmu:241489 mmu:29863 mmu:54611</Comment>
    <Graphics CenterX="2713.2557883131203" CenterY="188.09536000597984" Width="80.0" Height="20.0" ZOrder="34138" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="110385" />
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  <DataNode TextLabel="Nme7" GraphId="d39c3" Type="GeneProduct" GroupRef="bfdae">
    <Comment Source="KeggConverter">Original kegg element: gene;174;mmu:171567 mmu:18102 mmu:18103 mmu:54369 mmu:56520 mmu:75533 mmu:79059</Comment>
    <Graphics CenterX="3157.15789473684" CenterY="900.8046387154328" Width="80.0" Height="20.0" ZOrder="34139" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="171567" />
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  <DataNode TextLabel="Pnp2" GraphId="b1270" Type="GeneProduct" GroupRef="d560f">
    <Comment Source="KeggConverter">Original kegg element: gene;190;mmu:18950 mmu:667034</Comment>
    <Graphics CenterX="1804.3727454909813" CenterY="1084.0317244658825" Width="80.0" Height="20.0" ZOrder="34140" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="667034" />
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  <DataNode TextLabel="Adcy2" GraphId="f4ef4" Type="GeneProduct" GroupRef="e3f1d">
    <Comment Source="KeggConverter">Original kegg element: gene;166;mmu:104110 mmu:104111 mmu:11512 mmu:11513 mmu:11514 mmu:11515 mmu:210044 mmu:224129 mmu:271639 mmu:432530</Comment>
    <Graphics CenterX="3525.0385742900316" CenterY="702.0706628646263" Width="80.0" Height="20.0" ZOrder="34141" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="210044" />
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  <DataNode TextLabel="Pde10a" GraphId="ac724" Type="GeneProduct" GroupRef="f5806">
    <Comment Source="KeggConverter">Original kegg element: gene;165;mmu:110385 mmu:18573 mmu:18574 mmu:18575 mmu:18576 mmu:18577 mmu:18578 mmu:18583 mmu:18584 mmu:207728 mmu:218461 mmu:238871 mmu:23984 mmu:241489 mmu:29863 mmu:54611</Comment>
    <Graphics CenterX="2713.2557883131203" CenterY="308.09536000597984" Width="80.0" Height="20.0" ZOrder="34142" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="23984" />
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  <DataNode TextLabel="Pnp" GraphId="d4f67" Type="GeneProduct" GroupRef="cb412">
    <Comment Source="KeggConverter">Original kegg element: gene;218;mmu:18950 mmu:667034</Comment>
    <Graphics CenterX="967.9653679653674" CenterY="1311.6955022378743" Width="80.0" Height="20.0" ZOrder="34143" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="18950" />
  </DataNode>
  <DataNode TextLabel="Pde3b" GraphId="deed4" Type="GeneProduct" GroupRef="f5806">
    <Comment Source="KeggConverter">Original kegg element: gene;165;mmu:110385 mmu:18573 mmu:18574 mmu:18575 mmu:18576 mmu:18577 mmu:18578 mmu:18583 mmu:18584 mmu:207728 mmu:218461 mmu:238871 mmu:23984 mmu:241489 mmu:29863 mmu:54611</Comment>
    <Graphics CenterX="2713.2557883131203" CenterY="228.09536000597984" Width="80.0" Height="20.0" ZOrder="34144" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="18576" />
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  <DataNode TextLabel="Gart" GraphId="d3d27" Type="GeneProduct">
    <Comment Source="KeggConverter">Original kegg element: gene;158;mmu:14450</Comment>
    <Graphics CenterX="1317.6489028213157" CenterY="186.40008501142376" Width="80.0" Height="20.0" ZOrder="34145" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="14450" />
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  <DataNode TextLabel="dAMP" GraphId="ec4ae" Type="Metabolite">
    <Graphics CenterX="2727.9999999999995" CenterY="1110.0677966101696" Width="80.0" Height="20.0" ZOrder="34146" FontSize="10" Valign="Middle" Color="0000ff" />
    <Xref Database="KEGG Compound" ID="C00360" />
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  <DataNode TextLabel="Nt5e" GraphId="c478f" Type="GeneProduct" GroupRef="e79b1">
    <Comment Source="KeggConverter">Original kegg element: gene;186;mmu:103850 mmu:107569 mmu:230718 mmu:23959 mmu:50773 mmu:70881 mmu:76952</Comment>
    <Graphics CenterX="2829.0679910424597" CenterY="1169.8317654384518" Width="80.0" Height="20.0" ZOrder="34147" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="23959" />
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  <DataNode TextLabel="Pde6a" GraphId="e096d" Type="GeneProduct" GroupRef="e4165">
    <Comment Source="KeggConverter">Original kegg element: gene;245;mmu:110385 mmu:110855 mmu:18573 mmu:18574 mmu:18575 mmu:18576 mmu:18577 mmu:18578 mmu:18582 mmu:18583 mmu:18584 mmu:18585 mmu:18587 mmu:18588 mmu:207728 mmu:218461 mmu:225600 mmu:238871 mmu:23984 mmu:241489 mmu:242202 mmu:29863 mmu:54611 mmu:78600</Comment>
    <Graphics CenterX="141.79898241873565" CenterY="923.8574623569881" Width="80.0" Height="20.0" ZOrder="34148" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="225600" />
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  <DataNode TextLabel="Nme1" GraphId="ac6ea" Type="GeneProduct" GroupRef="e70b2">
    <Comment Source="KeggConverter">Original kegg element: gene;293;mmu:171567 mmu:18102 mmu:18103 mmu:54369 mmu:56520 mmu:75533 mmu:79059</Comment>
    <Graphics CenterX="851.9514884233737" CenterY="370.272868274999" Width="80.0" Height="20.0" ZOrder="34149" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="18102" />
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  <DataNode TextLabel="Guanosine 3'-diphosphate &#xA;5'-triphosphate" GraphId="d6fda" Type="Metabolite">
    <Graphics CenterX="562.7749360613823" CenterY="512.0824916554687" Width="133.22250639386215" Height="31.83761758203662" ZOrder="34150" FontSize="10" Valign="Middle" Color="0000ff" />
    <Xref Database="KEGG Compound" ID="C04494" />
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  <DataNode TextLabel="Nme1" GraphId="c8ef4" Type="GeneProduct" GroupRef="d2b7a">
    <Comment Source="KeggConverter">Original kegg element: gene;198;mmu:171567 mmu:18102 mmu:18103 mmu:54369 mmu:56520 mmu:75533 mmu:79059</Comment>
    <Graphics CenterX="1477.7289603052322" CenterY="456.5266710690438" Width="80.0" Height="20.0" ZOrder="34151" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="18102" />
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  <DataNode TextLabel="Nt5c1a" GraphId="af10b" Type="GeneProduct" GroupRef="bad2e">
    <Comment Source="KeggConverter">Original kegg element: gene;182;mmu:103850 mmu:107569 mmu:230718 mmu:23959 mmu:50773 mmu:70881 mmu:76952</Comment>
    <Graphics CenterX="2495.9226519337017" CenterY="922.8598558668044" Width="80.0" Height="20.0" ZOrder="34152" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="230718" />
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  <DataNode TextLabel="Dguok" GraphId="d23df" Type="GeneProduct">
    <Comment Source="KeggConverter">Original kegg element: gene;273;mmu:27369</Comment>
    <Graphics CenterX="1058.9523809523812" CenterY="1162.3708269131992" Width="80.0" Height="20.0" ZOrder="34153" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="27369" />
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  <DataNode TextLabel="Nme5" GraphId="a5afa" Type="GeneProduct" GroupRef="cf79b">
    <Comment Source="KeggConverter">Original kegg element: gene;175;mmu:171567 mmu:18102 mmu:18103 mmu:54369 mmu:56520 mmu:75533 mmu:79059</Comment>
    <Graphics CenterX="2941.409040793826" CenterY="1032.270663203334" Width="80.0" Height="20.0" ZOrder="34154" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="75533" />
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  <DataNode TextLabel="Nt5c2" GraphId="cde31" Type="GeneProduct" GroupRef="e7a69">
    <Comment Source="KeggConverter">Original kegg element: gene;215;mmu:103850 mmu:107569 mmu:230718 mmu:23959 mmu:50773 mmu:70881 mmu:76952</Comment>
    <Graphics CenterX="1765.196392785571" CenterY="976.0136883937391" Width="80.0" Height="20.0" ZOrder="34155" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="76952" />
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  <DataNode TextLabel="Pola1" GraphId="f8c74" Type="GeneProduct" GroupRef="d5f1e">
    <Comment Source="KeggConverter">Original kegg element: gene;170;mmu:18968 mmu:18969 mmu:18971 mmu:18972 mmu:18973 mmu:18974 mmu:19075 mmu:19076 mmu:59001 mmu:66979 mmu:67967 mmu:69745</Comment>
    <Graphics CenterX="3368.304299889746" CenterY="1009.2938164558147" Width="80.0" Height="20.0" ZOrder="34156" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="18968" />
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  <DataNode TextLabel="Nt5c1b" GraphId="ea8f4" Type="GeneProduct" GroupRef="b3409">
    <Comment Source="KeggConverter">Original kegg element: gene;239;mmu:103850 mmu:107569 mmu:230718 mmu:23959 mmu:50773 mmu:70881 mmu:76952</Comment>
    <Graphics CenterX="801.8095238095249" CenterY="1176.3881429305188" Width="80.0" Height="20.0" ZOrder="34157" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="70881" />
  </DataNode>
  <DataNode TextLabel="(-)-Ureidoglycolate" GraphId="cc8f6" Type="Metabolite">
    <Graphics CenterX="2554.0" CenterY="1478.0677966101696" Width="80.0" Height="20.0" ZOrder="34158" FontSize="10" Valign="Middle" Color="0000ff" />
    <Xref Database="KEGG Compound" ID="C00603" />
  </DataNode>
  <DataNode TextLabel="Nme7" GraphId="fb145" Type="GeneProduct" GroupRef="d2b7a">
    <Comment Source="KeggConverter">Original kegg element: gene;198;mmu:171567 mmu:18102 mmu:18103 mmu:54369 mmu:56520 mmu:75533 mmu:79059</Comment>
    <Graphics CenterX="1477.728960305232" CenterY="516.5266710690438" Width="80.0" Height="20.0" ZOrder="34159" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="171567" />
  </DataNode>
  <DataNode TextLabel="Pkm2" GraphId="e6a0d" Type="GeneProduct" GroupRef="ceecb">
    <Comment Source="KeggConverter">Original kegg element: gene;311;mmu:18746 mmu:18770</Comment>
    <Graphics CenterX="2932.947368421054" CenterY="890.1730597680637" Width="80.0" Height="20.0" ZOrder="34160" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="18746" />
  </DataNode>
  <DataNode TextLabel="Pde1a" GraphId="e2bf2" Type="GeneProduct" GroupRef="e4165">
    <Comment Source="KeggConverter">Original kegg element: gene;245;mmu:110385 mmu:110855 mmu:18573 mmu:18574 mmu:18575 mmu:18576 mmu:18577 mmu:18578 mmu:18582 mmu:18583 mmu:18584 mmu:18585 mmu:18587 mmu:18588 mmu:207728 mmu:218461 mmu:225600 mmu:238871 mmu:23984 mmu:241489 mmu:242202 mmu:29863 mmu:54611 mmu:78600</Comment>
    <Graphics CenterX="141.79898241873565" CenterY="783.8574623569884" Width="80.0" Height="20.0" ZOrder="34161" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="18573" />
  </DataNode>
  <DataNode TextLabel="5-amino-4-&#xA;imidazolecarboxyamide" GraphId="c1883" Type="Metabolite">
    <Graphics CenterX="2233.5" CenterY="234.21356463524796" Width="123.0" Height="31.0" ZOrder="34162" FontSize="10" Valign="Middle" Color="0000ff" />
    <Xref Database="KEGG Compound" ID="C04051" />
  </DataNode>
  <DataNode TextLabel="Pola1" GraphId="ad0bc" Type="GeneProduct" GroupRef="fc208">
    <Comment Source="KeggConverter">Original kegg element: gene;244;mmu:18968 mmu:18969 mmu:18971 mmu:18972 mmu:18973 mmu:18974 mmu:19075 mmu:19076 mmu:59001 mmu:66979 mmu:67967 mmu:69745</Comment>
    <Graphics CenterX="641.1601255886964" CenterY="995.9422079131535" Width="80.0" Height="20.0" ZOrder="34163" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="18968" />
  </DataNode>
  <DataNode TextLabel="Gmpr" GraphId="ff4f7" Type="GeneProduct" GroupRef="dcc3e">
    <Comment Source="KeggConverter">Original kegg element: gene;200;mmu:105446 mmu:66355</Comment>
    <Graphics CenterX="1663.1688311688313" CenterY="728.5006970430708" Width="80.0" Height="20.0" ZOrder="34164" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="66355" />
  </DataNode>
  <DataNode TextLabel="Polr3g" GraphId="a7829" Type="GeneProduct" GroupRef="afea2">
    <Comment Source="KeggConverter">Original kegg element: gene;168;mmu:100043714 mmu:100046796 mmu:20016 mmu:20017 mmu:20018 mmu:20019 mmu:20020 mmu:20021 mmu:20022 mmu:218832 mmu:231329 mmu:245841 mmu:26939 mmu:625405 mmu:64424 mmu:66136 mmu:66420 mmu:66491 mmu:67005 mmu:67065 mmu:67486 mmu:67710 mmu:69241 mmu:69833 mmu:69870 mmu:69920 mmu:70408 mmu:70428 mmu:74414 mmu:78929</Comment>
    <Graphics CenterX="3386.1100751994018" CenterY="622.762860154406" Width="90.94297214511298" Height="23.592612772064896" ZOrder="34165" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="67486" />
  </DataNode>
  <DataNode TextLabel="5-Phospho-alpha-D-ribose &#xA;1-diphosphate" GraphId="e409c" Type="Metabolite">
    <Graphics CenterX="488.52037617554856" CenterY="234.3593326603264" Width="124.04388714733554" Height="29.41692789968654" ZOrder="34166" FontSize="10" Valign="Middle" Color="0000ff" />
    <Xref Database="KEGG Compound" ID="C00119" />
  </DataNode>
  <DataNode TextLabel="Pde4a" GraphId="fb4ea" Type="GeneProduct" GroupRef="f5806">
    <Comment Source="KeggConverter">Original kegg element: gene;165;mmu:110385 mmu:18573 mmu:18574 mmu:18575 mmu:18576 mmu:18577 mmu:18578 mmu:18583 mmu:18584 mmu:207728 mmu:218461 mmu:238871 mmu:23984 mmu:241489 mmu:29863 mmu:54611</Comment>
    <Graphics CenterX="2633.2557883131203" CenterY="288.09536000597984" Width="80.0" Height="20.0" ZOrder="34167" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="18577" />
  </DataNode>
  <DataNode TextLabel="Pde8b" GraphId="bd175" Type="GeneProduct" GroupRef="e4165">
    <Comment Source="KeggConverter">Original kegg element: gene;245;mmu:110385 mmu:110855 mmu:18573 mmu:18574 mmu:18575 mmu:18576 mmu:18577 mmu:18578 mmu:18582 mmu:18583 mmu:18584 mmu:18585 mmu:18587 mmu:18588 mmu:207728 mmu:218461 mmu:225600 mmu:238871 mmu:23984 mmu:241489 mmu:242202 mmu:29863 mmu:54611 mmu:78600</Comment>
    <Graphics CenterX="141.79898241873565" CenterY="603.8574623569884" Width="80.0" Height="20.0" ZOrder="34168" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="218461" />
  </DataNode>
  <DataNode TextLabel="Entpd8" GraphId="ebf48" Type="GeneProduct" GroupRef="c0020">
    <Comment Source="KeggConverter">Original kegg element: gene;204;mmu:12495 mmu:215446 mmu:72090</Comment>
    <Graphics CenterX="1051.6010230179043" CenterY="685.1163899605533" Width="80.0" Height="20.0" ZOrder="34169" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="72090" />
  </DataNode>
  <DataNode TextLabel="Nt5c2" GraphId="a2b12" Type="GeneProduct" GroupRef="e79b1">
    <Comment Source="KeggConverter">Original kegg element: gene;186;mmu:103850 mmu:107569 mmu:230718 mmu:23959 mmu:50773 mmu:70881 mmu:76952</Comment>
    <Graphics CenterX="2829.0679910424597" CenterY="1209.8317654384516" Width="80.0" Height="20.0" ZOrder="34170" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="76952" />
  </DataNode>
  <DataNode TextLabel="Pola2" GraphId="a6af9" Type="GeneProduct" GroupRef="fc208">
    <Comment Source="KeggConverter">Original kegg element: gene;244;mmu:18968 mmu:18969 mmu:18971 mmu:18972 mmu:18973 mmu:18974 mmu:19075 mmu:19076 mmu:59001 mmu:66979 mmu:67967 mmu:69745</Comment>
    <Graphics CenterX="561.0973312401883" CenterY="1095.2514700795577" Width="80.0" Height="20.0" ZOrder="34171" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="18969" />
  </DataNode>
  <DataNode TextLabel="dATP" GraphId="a037e" Type="Metabolite">
    <Graphics CenterX="3050.0" CenterY="942.0677966101696" Width="79.99999999999994" Height="25.660874519299295" ZOrder="34172" FontSize="10" Valign="Middle" Color="0000ff" />
    <Xref Database="KEGG Compound" ID="C00131" />
  </DataNode>
  <DataNode TextLabel="Guanosine 3',5'-&#xA;bis(diphosphate)" GraphId="d65b5" Type="Metabolite">
    <Graphics CenterX="737.2710997442451" CenterY="512.0824916554687" Width="95.79028132992393" Height="31.804326151979012" ZOrder="34173" FontSize="10" Valign="Middle" Color="0000ff" />
    <Xref Database="KEGG Compound" ID="C01228" />
  </DataNode>
  <DataNode TextLabel="Guanosine" GraphId="e4eee" Type="Metabolite">
    <Graphics CenterX="1318.0" CenterY="994.0677966101696" Width="80.0" Height="20.0" ZOrder="34174" FontSize="10" Valign="Middle" Color="0000ff" />
    <Xref Database="KEGG Compound" ID="C00387" />
  </DataNode>
  <DataNode TextLabel="Hprt" GraphId="d253d" Type="GeneProduct">
    <Comment Source="KeggConverter">Original kegg element: gene;213;mmu:15452</Comment>
    <Graphics CenterX="1536.6292585170368" CenterY="1021.9916443055595" Width="80.0" Height="20.0" ZOrder="34175" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="15452" />
  </DataNode>
  <DataNode TextLabel="Nt5c1a" GraphId="b22e3" Type="GeneProduct" GroupRef="e79b1">
    <Comment Source="KeggConverter">Original kegg element: gene;186;mmu:103850 mmu:107569 mmu:230718 mmu:23959 mmu:50773 mmu:70881 mmu:76952</Comment>
    <Graphics CenterX="2909.0679910424597" CenterY="1169.8317654384516" Width="80.0" Height="20.0" ZOrder="34176" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="230718" />
  </DataNode>
  <DataNode TextLabel="Gm13015" GraphId="cb11e" Type="GeneProduct" GroupRef="c746a">
    <Comment Source="KeggConverter">Original kegg element: gene;241;mmu:100043714 mmu:100046796 mmu:20016 mmu:20017 mmu:20018 mmu:20019 mmu:20020 mmu:20021 mmu:20022 mmu:218832 mmu:231329 mmu:245841 mmu:26939 mmu:625405 mmu:64424 mmu:66136 mmu:66420 mmu:66491 mmu:67005 mmu:67065 mmu:67486 mmu:67710 mmu:69241 mmu:69833 mmu:69870 mmu:69920 mmu:70408 mmu:70428 mmu:74414 mmu:78929</Comment>
    <Graphics CenterX="19.048068185003256" CenterY="1266.275352877791" Width="92.46225755421057" Height="25.554043353358804" ZOrder="34177" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="625405" />
  </DataNode>
  <DataNode TextLabel="Npr2" GraphId="b0e10" Type="GeneProduct" GroupRef="e83ec">
    <Comment Source="KeggConverter">Original kegg element: gene;243;mmu:14917 mmu:14918 mmu:14919 mmu:18160 mmu:230103 mmu:234889 mmu:239134 mmu:245650 mmu:54195 mmu:60596</Comment>
    <Graphics CenterX="263.6371674701754" CenterY="795.4877239289058" Width="80.0" Height="20.0" ZOrder="34178" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="230103" />
  </DataNode>
  <DataNode TextLabel="L-Glutamine" GraphId="a2f24" Type="Metabolite">
    <Graphics CenterX="488.52037617554856" CenterY="343.41575899261454" Width="80.0" Height="20.0" ZOrder="34179" FontSize="10" Valign="Middle" Color="0000ff" />
    <Xref Database="KEGG Compound" ID="C00064" />
  </DataNode>
  <DataNode TextLabel="Ak1" GraphId="babe3" Type="GeneProduct" GroupRef="b11a0">
    <Comment Source="KeggConverter">Original kegg element: gene;178;mmu:11636 mmu:11637 mmu:11639 mmu:229949 mmu:78801</Comment>
    <Graphics CenterX="2514.2679558011055" CenterY="682.2124028467089" Width="80.0" Height="20.0" ZOrder="34180" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="11636" />
  </DataNode>
  <DataNode TextLabel="Entpd3" GraphId="bb669" Type="GeneProduct" GroupRef="bd17f">
    <Comment Source="KeggConverter">Original kegg element: gene;199;mmu:12495 mmu:215446 mmu:72090</Comment>
    <Graphics CenterX="1630.1744808863455" CenterY="647.5180864333413" Width="80.0" Height="20.0" ZOrder="34181" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="215446" />
  </DataNode>
  <DataNode TextLabel="Pde1b" GraphId="d66a2" Type="GeneProduct" GroupRef="f5806">
    <Comment Source="KeggConverter">Original kegg element: gene;165;mmu:110385 mmu:18573 mmu:18574 mmu:18575 mmu:18576 mmu:18577 mmu:18578 mmu:18583 mmu:18584 mmu:207728 mmu:218461 mmu:238871 mmu:23984 mmu:241489 mmu:29863 mmu:54611</Comment>
    <Graphics CenterX="2713.2557883131203" CenterY="208.09536000597984" Width="80.0" Height="20.0" ZOrder="34182" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="18574" />
  </DataNode>
  <DataNode TextLabel="Guanine" GraphId="f84bd" Type="Metabolite">
    <Graphics CenterX="1318.0" CenterY="1192.0920830581847" Width="80.00000000000007" Height="31.951427103969714" ZOrder="34183" FontSize="10" Valign="Middle" Color="0000ff" />
    <Xref Database="KEGG Compound" ID="C00242" />
  </DataNode>
  <DataNode TextLabel="Ak2" GraphId="f0f6a" Type="GeneProduct" GroupRef="d54ef">
    <Comment Source="KeggConverter">Original kegg element: gene;285;mmu:11636 mmu:11637 mmu:11639 mmu:229949 mmu:78801</Comment>
    <Graphics CenterX="2601.0373715597634" CenterY="1015.7173004204114" Width="80.0" Height="20.0" ZOrder="34184" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="11637" />
  </DataNode>
  <DataNode TextLabel="Rrm2b" GraphId="a436c" Type="GeneProduct" GroupRef="e1c60">
    <Comment Source="KeggConverter">Original kegg element: gene;133;mmu:20133 mmu:20135 mmu:382985</Comment>
    <Graphics CenterX="1074.9515616523279" CenterY="901.5401673766575" Width="80.0" Height="20.0" ZOrder="34185" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="382985" />
  </DataNode>
  <DataNode TextLabel="Pold3" GraphId="ef563" Type="GeneProduct" GroupRef="d5f1e">
    <Comment Source="KeggConverter">Original kegg element: gene;170;mmu:18968 mmu:18969 mmu:18971 mmu:18972 mmu:18973 mmu:18974 mmu:19075 mmu:19076 mmu:59001 mmu:66979 mmu:67967 mmu:69745</Comment>
    <Graphics CenterX="3368.304299889746" CenterY="1109.293816455815" Width="80.0" Height="20.0" ZOrder="34186" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="67967" />
  </DataNode>
  <DataNode TextLabel="Polr2g" GraphId="cb4b0" Type="GeneProduct" GroupRef="c746a">
    <Comment Source="KeggConverter">Original kegg element: gene;241;mmu:100043714 mmu:100046796 mmu:20016 mmu:20017 mmu:20018 mmu:20019 mmu:20020 mmu:20021 mmu:20022 mmu:218832 mmu:231329 mmu:245841 mmu:26939 mmu:625405 mmu:64424 mmu:66136 mmu:66420 mmu:66491 mmu:67005 mmu:67065 mmu:67486 mmu:67710 mmu:69241 mmu:69833 mmu:69870 mmu:69920 mmu:70408 mmu:70428 mmu:74414 mmu:78929</Comment>
    <Graphics CenterX="19.048068185003256" CenterY="1164.0591794643553" Width="92.46225755421057" Height="25.554043353358804" ZOrder="34187" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="67710" />
  </DataNode>
  <DataNode TextLabel="Nt5m" GraphId="db060" Type="GeneProduct" GroupRef="e7a69">
    <Comment Source="KeggConverter">Original kegg element: gene;215;mmu:103850 mmu:107569 mmu:230718 mmu:23959 mmu:50773 mmu:70881 mmu:76952</Comment>
    <Graphics CenterX="1765.196392785571" CenterY="916.0136883937395" Width="80.0" Height="20.0" ZOrder="34188" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="103850" />
  </DataNode>
  <DataNode TextLabel="Pnp" GraphId="d1c9e" Type="GeneProduct" GroupRef="d560f">
    <Comment Source="KeggConverter">Original kegg element: gene;190;mmu:18950 mmu:667034</Comment>
    <Graphics CenterX="1804.3727454909813" CenterY="1104.0317244658825" Width="80.0" Height="20.0" ZOrder="34189" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="18950" />
  </DataNode>
  <DataNode TextLabel="Nt5c1b" GraphId="aa2d2" Type="GeneProduct" GroupRef="e79b1">
    <Comment Source="KeggConverter">Original kegg element: gene;186;mmu:103850 mmu:107569 mmu:230718 mmu:23959 mmu:50773 mmu:70881 mmu:76952</Comment>
    <Graphics CenterX="2829.0679910424597" CenterY="1149.831765438452" Width="80.0" Height="20.0" ZOrder="34190" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="70881" />
  </DataNode>
  <DataNode TextLabel="Pde3a" GraphId="b7e38" Type="GeneProduct" GroupRef="e4165">
    <Comment Source="KeggConverter">Original kegg element: gene;245;mmu:110385 mmu:110855 mmu:18573 mmu:18574 mmu:18575 mmu:18576 mmu:18577 mmu:18578 mmu:18582 mmu:18583 mmu:18584 mmu:18585 mmu:18587 mmu:18588 mmu:207728 mmu:218461 mmu:225600 mmu:238871 mmu:23984 mmu:241489 mmu:242202 mmu:29863 mmu:54611 mmu:78600</Comment>
    <Graphics CenterX="141.79898241873565" CenterY="983.8574623569883" Width="80.0" Height="20.0" ZOrder="34191" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="54611" />
  </DataNode>
  <DataNode TextLabel="dIDP" GraphId="c1e36" Type="Metabolite">
    <Graphics CenterX="795.6427783902974" CenterY="474.0655915385048" Width="80.0" Height="20.0" ZOrder="34192" FontSize="10" Valign="Middle" Color="0000ff" />
    <Xref Database="KEGG Compound" ID="C01344" />
  </DataNode>
  <DataNode TextLabel="Hprt" GraphId="a926a" Type="GeneProduct">
    <Comment Source="KeggConverter">Original kegg element: gene;216;mmu:15452</Comment>
    <Graphics CenterX="1105.926406926408" CenterY="1076.2063247486974" Width="53.97402597402728" Height="19.999999999999922" ZOrder="34193" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="15452" />
  </DataNode>
  <DataNode TextLabel="Polr3e" GraphId="a866f" Type="GeneProduct" GroupRef="c746a">
    <Comment Source="KeggConverter">Original kegg element: gene;241;mmu:100043714 mmu:100046796 mmu:20016 mmu:20017 mmu:20018 mmu:20019 mmu:20020 mmu:20021 mmu:20022 mmu:218832 mmu:231329 mmu:245841 mmu:26939 mmu:625405 mmu:64424 mmu:66136 mmu:66420 mmu:66491 mmu:67005 mmu:67065 mmu:67486 mmu:67710 mmu:69241 mmu:69833 mmu:69870 mmu:69920 mmu:70408 mmu:70428 mmu:74414 mmu:78929</Comment>
    <Graphics CenterX="204.2166917255102" CenterY="1086.866003642738" Width="92.46225755421065" Height="25.554043353358804" ZOrder="34194" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="26939" />
  </DataNode>
  <DataNode TextLabel="ITP" GraphId="a9265" Type="Metabolite">
    <Graphics CenterX="1527.3559322033898" CenterY="579.4237288135594" Width="80.00000000000007" Height="31.951427103969714" ZOrder="34195" FontSize="10" Valign="Middle" Color="0000ff" />
    <Xref Database="KEGG Compound" ID="C00081" />
  </DataNode>
  <DataNode TextLabel="Entpd2" GraphId="ff8c2" Type="GeneProduct">
    <Comment Source="KeggConverter">Original kegg element: gene;172;mmu:12496</Comment>
    <Graphics CenterX="2896.209944751385" CenterY="643.9683490963574" Width="80.0" Height="20.0" ZOrder="34196" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="12496" />
  </DataNode>
  <DataNode TextLabel="Urah" GraphId="c1588" Type="GeneProduct">
    <Comment Source="KeggConverter">Original kegg element: gene;229;mmu:76974</Comment>
    <Graphics CenterX="1755.7922077922087" CenterY="1441.7041602465324" Width="80.0" Height="20.0" ZOrder="34197" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="76974" />
  </DataNode>
  <DataNode TextLabel="Entpd8" GraphId="c16e5" Type="GeneProduct" GroupRef="d409a">
    <Comment Source="KeggConverter">Original kegg element: gene;234;mmu:12495 mmu:215446 mmu:72090</Comment>
    <Graphics CenterX="919.6317135549864" CenterY="711.3465689886862" Width="80.0" Height="20.0" ZOrder="34199" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="72090" />
  </DataNode>
  <DataNode TextLabel="Pold4" GraphId="adf01" Type="GeneProduct" GroupRef="d5f1e">
    <Comment Source="KeggConverter">Original kegg element: gene;170;mmu:18968 mmu:18969 mmu:18971 mmu:18972 mmu:18973 mmu:18974 mmu:19075 mmu:19076 mmu:59001 mmu:66979 mmu:67967 mmu:69745</Comment>
    <Graphics CenterX="3288.304299889746" CenterY="1009.2938164558145" Width="80.0" Height="20.0" ZOrder="34201" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="69745" />
  </DataNode>
  <DataNode TextLabel="3'-Phosphoadenylyl &#xA;sulfate" GraphId="cdabb" Type="Metabolite">
    <Graphics CenterX="3005.7304299889747" CenterY="355.0573225197615" Width="97.0" Height="27.0" ZOrder="34202" FontSize="10" Valign="Middle" Color="0000ff" />
    <Xref Database="KEGG Compound" ID="C00053" />
  </DataNode>
  <DataNode TextLabel="Itpa" GraphId="eb3ee" Type="GeneProduct">
    <Comment Source="KeggConverter">Original kegg element: gene;263;mmu:16434</Comment>
    <Graphics CenterX="1514.092561382638" CenterY="836.4181815941413" Width="80.0" Height="20.0" ZOrder="34203" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="16434" />
  </DataNode>
  <DataNode TextLabel="Riboflavin &#xA;metabolism" GraphId="bb467" Type="Pathway">
    <Comment Source="KeggConverter">Original kegg element: map;252;path:mmu00740</Comment>
    <Graphics CenterX="305.51270553064273" CenterY="922.7738086189851" Width="82.0" Height="29.93220338983042" ZOrder="34205" FontWeight="Bold" FontSize="10" Valign="Middle" Color="14961e" />
    <Xref Database="WikiPathways" ID="WP1273" />
  </DataNode>
  <DataNode TextLabel="Adcy6" GraphId="a4acf" Type="GeneProduct" GroupRef="ae4c5">
    <Comment Source="KeggConverter">Original kegg element: gene;297;mmu:104110 mmu:104111 mmu:11512 mmu:11513 mmu:11514 mmu:11515 mmu:210044 mmu:224129 mmu:271639 mmu:432530</Comment>
    <Graphics CenterX="369.7182662538706" CenterY="773.7456805784034" Width="80.0" Height="20.0" ZOrder="34206" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="11512" />
  </DataNode>
  <DataNode TextLabel="Pkm2" GraphId="fc018" Type="GeneProduct" GroupRef="b81f1">
    <Comment Source="KeggConverter">Original kegg element: gene;310;mmu:18746 mmu:18770</Comment>
    <Graphics CenterX="2831.15545755237" CenterY="1007.9641582419229" Width="80.0" Height="20.0" ZOrder="34207" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="18746" />
  </DataNode>
  <DataNode TextLabel="Adprm" GraphId="faa95" Type="GeneProduct" GroupRef="a021a">
    <Comment Source="KeggConverter">Original kegg element: gene;280;mmu:53893 mmu:66358 mmu:74167 aka 2310004I24Rik</Comment>
    <Graphics CenterX="218.10447761194033" CenterY="439.85884138628853" Width="80.0" Height="20.0" ZOrder="34208" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="66358" />
  </DataNode>
  <DataNode TextLabel="Pde4d" GraphId="d0d10" Type="GeneProduct" GroupRef="e4165">
    <Comment Source="KeggConverter">Original kegg element: gene;245;mmu:110385 mmu:110855 mmu:18573 mmu:18574 mmu:18575 mmu:18576 mmu:18577 mmu:18578 mmu:18582 mmu:18583 mmu:18584 mmu:18585 mmu:18587 mmu:18588 mmu:207728 mmu:218461 mmu:225600 mmu:238871 mmu:23984 mmu:241489 mmu:242202 mmu:29863 mmu:54611 mmu:78600</Comment>
    <Graphics CenterX="141.79898241873565" CenterY="583.8574623569884" Width="80.0" Height="20.0" ZOrder="34209" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="238871" />
  </DataNode>
  <DataNode TextLabel="ADP-ribose" GraphId="fccd2" Type="Metabolite">
    <Graphics CenterX="117.7014925373133" CenterY="396.7842145206175" Width="80.0" Height="20.0" ZOrder="34210" FontSize="10" Valign="Middle" Color="0000ff" />
    <Xref Database="KEGG Compound" ID="C00301" />
  </DataNode>
  <DataNode TextLabel="Nt5c3" GraphId="d3b2c" Type="GeneProduct" GroupRef="e79b1">
    <Comment Source="KeggConverter">Original kegg element: gene;186;mmu:103850 mmu:107569 mmu:230718 mmu:23959 mmu:50773 mmu:70881 mmu:76952</Comment>
    <Graphics CenterX="2829.0679910424597" CenterY="1189.8317654384516" Width="80.0" Height="20.0" ZOrder="34211" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="107569" />
  </DataNode>
  <DataNode TextLabel="Adenine" GraphId="a6547" Type="Metabolite">
    <Graphics CenterX="2402.0" CenterY="1200.0677966101696" Width="80.00000000000014" Height="25.660874519299334" ZOrder="34212" FontSize="10" Valign="Middle" Color="0000ff" />
    <Xref Database="KEGG Compound" ID="C00147" />
  </DataNode>
  <DataNode TextLabel="Polr1c" GraphId="f92a2" Type="GeneProduct" GroupRef="afea2">
    <Comment Source="KeggConverter">Original kegg element: gene;168;mmu:100043714 mmu:100046796 mmu:20016 mmu:20017 mmu:20018 mmu:20019 mmu:20020 mmu:20021 mmu:20022 mmu:218832 mmu:231329 mmu:245841 mmu:26939 mmu:625405 mmu:64424 mmu:66136 mmu:66420 mmu:66491 mmu:67005 mmu:67065 mmu:67486 mmu:67710 mmu:69241 mmu:69833 mmu:69870 mmu:69920 mmu:70408 mmu:70428 mmu:74414 mmu:78929</Comment>
    <Graphics CenterX="3295.1671030542884" CenterY="646.3554729264708" Width="90.94297214511298" Height="23.592612772064896" ZOrder="34213" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="20016" />
  </DataNode>
  <DataNode TextLabel="Polr2a" GraphId="fb61c" Type="GeneProduct" GroupRef="afea2">
    <Comment Source="KeggConverter">Original kegg element: gene;168;mmu:100043714 mmu:100046796 mmu:20016 mmu:20017 mmu:20018 mmu:20019 mmu:20020 mmu:20021 mmu:20022 mmu:218832 mmu:231329 mmu:245841 mmu:26939 mmu:625405 mmu:64424 mmu:66136 mmu:66420 mmu:66491 mmu:67005 mmu:67065 mmu:67486 mmu:67710 mmu:69241 mmu:69833 mmu:69870 mmu:69920 mmu:70408 mmu:70428 mmu:74414 mmu:78929</Comment>
    <Graphics CenterX="3295.1671030542884" CenterY="693.5406984706007" Width="90.94297214511298" Height="23.592612772064896" ZOrder="34215" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="20020" />
  </DataNode>
  <DataNode TextLabel="Pola2" GraphId="bb389" Type="GeneProduct" GroupRef="d5f1e">
    <Comment Source="KeggConverter">Original kegg element: gene;170;mmu:18968 mmu:18969 mmu:18971 mmu:18972 mmu:18973 mmu:18974 mmu:19075 mmu:19076 mmu:59001 mmu:66979 mmu:67967 mmu:69745</Comment>
    <Graphics CenterX="3288.304299889746" CenterY="1109.2938164558147" Width="80.0" Height="20.0" ZOrder="34216" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="18969" />
  </DataNode>
  <DataNode TextLabel="Ampd1" GraphId="b4911" Type="GeneProduct" GroupRef="ad6d1">
    <Comment Source="KeggConverter">Original kegg element: gene;181;mmu:109674 mmu:11717 mmu:229665</Comment>
    <Graphics CenterX="2202.083969465647" CenterY="730.8693233277272" Width="80.0" Height="20.0" ZOrder="34217" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="229665" />
  </DataNode>
  <DataNode TextLabel="Polr3h" GraphId="b2e83" Type="GeneProduct" GroupRef="afea2">
    <Comment Source="KeggConverter">Original kegg element: gene;168;mmu:100043714 mmu:100046796 mmu:20016 mmu:20017 mmu:20018 mmu:20019 mmu:20020 mmu:20021 mmu:20022 mmu:218832 mmu:231329 mmu:245841 mmu:26939 mmu:625405 mmu:64424 mmu:66136 mmu:66420 mmu:66491 mmu:67005 mmu:67065 mmu:67486 mmu:67710 mmu:69241 mmu:69833 mmu:69870 mmu:69920 mmu:70408 mmu:70428 mmu:74414 mmu:78929</Comment>
    <Graphics CenterX="3204.224130909176" CenterY="504.7997962940815" Width="90.94297214511298" Height="23.592612772064896" ZOrder="34218" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="78929" />
  </DataNode>
  <DataNode TextLabel="GMP" GraphId="b4af3" Type="Metabolite">
    <Graphics CenterX="1318.0" CenterY="792.3258611262987" Width="80.00000000000007" Height="37.053435114503905" ZOrder="34219" FontSize="10" Valign="Middle" Color="0000ff" />
    <Xref Database="KEGG Compound" ID="C00144" />
  </DataNode>
  <DataNode TextLabel="Polr1e" GraphId="d7c41" Type="GeneProduct" GroupRef="afea2">
    <Comment Source="KeggConverter">Original kegg element: gene;168;mmu:100043714 mmu:100046796 mmu:20016 mmu:20017 mmu:20018 mmu:20019 mmu:20020 mmu:20021 mmu:20022 mmu:218832 mmu:231329 mmu:245841 mmu:26939 mmu:625405 mmu:64424 mmu:66136 mmu:66420 mmu:66491 mmu:67005 mmu:67065 mmu:67486 mmu:67710 mmu:69241 mmu:69833 mmu:69870 mmu:69920 mmu:70408 mmu:70428 mmu:74414 mmu:78929</Comment>
    <Graphics CenterX="3386.1100751994018" CenterY="551.9850218382113" Width="90.94297214511298" Height="23.592612772064896" ZOrder="34220" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="64424" />
  </DataNode>
  <DataNode TextLabel="Pde7a" GraphId="b50fc" Type="GeneProduct" GroupRef="f5806">
    <Comment Source="KeggConverter">Original kegg element: gene;165;mmu:110385 mmu:18573 mmu:18574 mmu:18575 mmu:18576 mmu:18577 mmu:18578 mmu:18583 mmu:18584 mmu:207728 mmu:218461 mmu:238871 mmu:23984 mmu:241489 mmu:29863 mmu:54611</Comment>
    <Graphics CenterX="2633.2557883131203" CenterY="268.09536000597984" Width="80.0" Height="20.0" ZOrder="34221" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="18583" />
  </DataNode>
  <DataNode TextLabel="Pole2" GraphId="afd0f" Type="GeneProduct" GroupRef="fc208">
    <Comment Source="KeggConverter">Original kegg element: gene;244;mmu:18968 mmu:18969 mmu:18971 mmu:18972 mmu:18973 mmu:18974 mmu:19075 mmu:19076 mmu:59001 mmu:66979 mmu:67967 mmu:69745</Comment>
    <Graphics CenterX="561.0973312401883" CenterY="1055.2514700795577" Width="80.0" Height="20.0" ZOrder="34222" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="18974" />
  </DataNode>
  <DataNode TextLabel="Pde1b" GraphId="d90b5" Type="GeneProduct" GroupRef="e4165">
    <Comment Source="KeggConverter">Original kegg element: gene;245;mmu:110385 mmu:110855 mmu:18573 mmu:18574 mmu:18575 mmu:18576 mmu:18577 mmu:18578 mmu:18582 mmu:18583 mmu:18584 mmu:18585 mmu:18587 mmu:18588 mmu:207728 mmu:218461 mmu:225600 mmu:238871 mmu:23984 mmu:241489 mmu:242202 mmu:29863 mmu:54611 mmu:78600</Comment>
    <Graphics CenterX="141.79898241873565" CenterY="723.8574623569884" Width="80.0" Height="20.0" ZOrder="34223" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="18574" />
  </DataNode>
  <DataNode TextLabel="Nudt2" GraphId="a5ade" Type="GeneProduct">
    <Comment Source="KeggConverter">Original kegg element: gene;271;mmu:66401</Comment>
    <Graphics CenterX="555.0" CenterY="856.3879822250187" Width="80.0" Height="20.0" ZOrder="34224" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="66401" />
  </DataNode>
  <DataNode TextLabel="Entpd3" GraphId="d8943" Type="GeneProduct" GroupRef="d409a">
    <Comment Source="KeggConverter">Original kegg element: gene;234;mmu:12495 mmu:215446 mmu:72090</Comment>
    <Graphics CenterX="919.6317135549864" CenterY="671.3465689886862" Width="80.0" Height="20.0" ZOrder="34225" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="215446" />
  </DataNode>
  <DataNode TextLabel="Prps1" GraphId="f89d7" Type="GeneProduct" GroupRef="ad65e">
    <Comment Source="KeggConverter">Original kegg element: gene;153;mmu:110639 mmu:19139 mmu:328099 mmu:75456</Comment>
    <Graphics CenterX="391.9686520376172" CenterY="161.03958344402525" Width="80.0" Height="20.0" ZOrder="34226" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="19139" />
  </DataNode>
  <DataNode TextLabel="Pnpt1" GraphId="df80f" Type="GeneProduct">
    <Comment Source="KeggConverter">Original kegg element: gene;164;mmu:71701</Comment>
    <Graphics CenterX="2962.4693009380453" CenterY="676.3903111702206" Width="80.0" Height="20.0" ZOrder="34227" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="71701" />
  </DataNode>
  <DataNode TextLabel="Pnp" GraphId="dfaca" Type="GeneProduct" GroupRef="e06f0">
    <Comment Source="KeggConverter">Original kegg element: gene;208;mmu:18950 mmu:667034</Comment>
    <Graphics CenterX="2326.0779220779214" CenterY="1075.2019957443677" Width="80.0" Height="20.0" ZOrder="34228" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="18950" />
  </DataNode>
  <DataNode TextLabel="Adcy8" GraphId="dfb16" Type="GeneProduct" GroupRef="e3f1d">
    <Comment Source="KeggConverter">Original kegg element: gene;166;mmu:104110 mmu:104111 mmu:11512 mmu:11513 mmu:11514 mmu:11515 mmu:210044 mmu:224129 mmu:271639 mmu:432530</Comment>
    <Graphics CenterX="3525.0385742900316" CenterY="682.0706628646263" Width="80.0" Height="20.0" ZOrder="34229" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="11514" />
  </DataNode>
  <DataNode TextLabel="Polr1c" GraphId="a9785" Type="GeneProduct" GroupRef="c746a">
    <Comment Source="KeggConverter">Original kegg element: gene;241;mmu:100043714 mmu:100046796 mmu:20016 mmu:20017 mmu:20018 mmu:20019 mmu:20020 mmu:20021 mmu:20022 mmu:218832 mmu:231329 mmu:245841 mmu:26939 mmu:625405 mmu:64424 mmu:66136 mmu:66420 mmu:66491 mmu:67005 mmu:67065 mmu:67486 mmu:67710 mmu:69241 mmu:69833 mmu:69870 mmu:69920 mmu:70408 mmu:70428 mmu:74414 mmu:78929</Comment>
    <Graphics CenterX="110.76377692730505" CenterY="1215.3836045649869" Width="92.46225755421065" Height="25.554043353358804" ZOrder="34230" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="20016" />
  </DataNode>
  <DataNode TextLabel="Pnp2" GraphId="ce602" Type="GeneProduct" GroupRef="e06f0">
    <Comment Source="KeggConverter">Original kegg element: gene;208;mmu:18950 mmu:667034</Comment>
    <Graphics CenterX="2326.0779220779214" CenterY="1055.2019957443677" Width="80.0" Height="20.0" ZOrder="34231" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="667034" />
  </DataNode>
  <DataNode TextLabel="Nme6" GraphId="dd0dc" Type="GeneProduct" GroupRef="cf79b">
    <Comment Source="KeggConverter">Original kegg element: gene;175;mmu:171567 mmu:18102 mmu:18103 mmu:54369 mmu:56520 mmu:75533 mmu:79059</Comment>
    <Graphics CenterX="3021.409040793826" CenterY="1032.270663203334" Width="80.0" Height="20.0" ZOrder="34232" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="54369" />
  </DataNode>
  <DataNode TextLabel="Ak5" GraphId="e9fd2" Type="GeneProduct" GroupRef="b11a0">
    <Comment Source="KeggConverter">Original kegg element: gene;178;mmu:11636 mmu:11637 mmu:11639 mmu:229949 mmu:78801</Comment>
    <Graphics CenterX="2514.2679558011055" CenterY="642.2124028467089" Width="80.0000000000001" Height="20.000000000000025" ZOrder="34233" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="229949" />
  </DataNode>
  <DataNode TextLabel="1-(5-Phospho-D-ribosyl)-5-amino&#xA;-4-imidazolecarboxylate" GraphId="f2e8c" Type="Metabolite">
    <Graphics CenterX="1598.241379310346" CenterY="234.56779661016958" Width="156.48275862068937" Height="27.416927899686364" ZOrder="34234" FontSize="10" Valign="Middle" Color="0000ff" />
    <Xref Database="KEGG Compound" ID="C04751" />
  </DataNode>
  <DataNode TextLabel="Xanthosine" GraphId="dbf2f" Type="Metabolite">
    <Graphics CenterX="1668.0" CenterY="986.0677966101696" Width="80.0" Height="20.0" ZOrder="34235" FontSize="10" Valign="Middle" Color="0000ff" />
    <Xref Database="KEGG Compound" ID="C01762" />
  </DataNode>
  <DataNode TextLabel="Pnp2" GraphId="a0dae" Type="GeneProduct" GroupRef="ee230">
    <Comment Source="KeggConverter">Original kegg element: gene;188;mmu:18950 mmu:667034</Comment>
    <Graphics CenterX="2696.3640322121446" CenterY="1253.5577172318106" Width="80.0" Height="20.0" ZOrder="34236" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="667034" />
  </DataNode>
  <DataNode TextLabel="1-(5'-Phosphoribosyl)-5-formamido&#xA;-4-imidazolecarboxamide" GraphId="e3d53" Type="Metabolite">
    <Comment>aka FAICAR</Comment>
    <Graphics CenterX="2019.4736842105272" CenterY="363.0677966101696" Width="158.0" Height="30.0" ZOrder="34237" FontSize="10" Valign="Middle" Color="0000ff" />
    <Xref Database="KEGG Compound" ID="C04734" />
  </DataNode>
  <DataNode TextLabel="Nt5c1a" GraphId="c3fa0" Type="GeneProduct" GroupRef="b3409">
    <Comment Source="KeggConverter">Original kegg element: gene;239;mmu:103850 mmu:107569 mmu:230718 mmu:23959 mmu:50773 mmu:70881 mmu:76952</Comment>
    <Graphics CenterX="961.8095238095249" CenterY="1176.3881429305188" Width="80.0" Height="20.0" ZOrder="34238" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="230718" />
  </DataNode>
  <DataNode TextLabel="Nt5c1b" GraphId="a11b0" Type="GeneProduct" GroupRef="a692d">
    <Comment Source="KeggConverter">Original kegg element: gene;210;mmu:103850 mmu:107569 mmu:230718 mmu:23959 mmu:50773 mmu:70881 mmu:76952</Comment>
    <Graphics CenterX="1229.3511450381689" CenterY="839.3349721826894" Width="80.0" Height="20.0" ZOrder="34239" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="70881" />
  </DataNode>
  <DataNode TextLabel="Polr2b" GraphId="b1271" Type="GeneProduct" GroupRef="afea2">
    <Comment Source="KeggConverter">Original kegg element: gene;168;mmu:100043714 mmu:100046796 mmu:20016 mmu:20017 mmu:20018 mmu:20019 mmu:20020 mmu:20021 mmu:20022 mmu:218832 mmu:231329 mmu:245841 mmu:26939 mmu:625405 mmu:64424 mmu:66136 mmu:66420 mmu:66491 mmu:67005 mmu:67065 mmu:67486 mmu:67710 mmu:69241 mmu:69833 mmu:69870 mmu:69920 mmu:70408 mmu:70428 mmu:74414 mmu:78929</Comment>
    <Graphics CenterX="3386.1100751994018" CenterY="504.7997962940815" Width="90.94297214511298" Height="23.592612772064896" ZOrder="34240" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="231329" />
  </DataNode>
  <DataNode TextLabel="Pole" GraphId="ff33e" Type="GeneProduct" GroupRef="d5f1e">
    <Comment Source="KeggConverter">Original kegg element: gene;170;mmu:18968 mmu:18969 mmu:18971 mmu:18972 mmu:18973 mmu:18974 mmu:19075 mmu:19076 mmu:59001 mmu:66979 mmu:67967 mmu:69745</Comment>
    <Graphics CenterX="3368.304299889746" CenterY="1049.2938164558147" Width="80.0" Height="20.0" ZOrder="34241" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="18973" />
  </DataNode>
  <DataNode TextLabel="Pde11a" GraphId="e03b3" Type="GeneProduct" GroupRef="e4165">
    <Comment Source="KeggConverter">Original kegg element: gene;245;mmu:110385 mmu:110855 mmu:18573 mmu:18574 mmu:18575 mmu:18576 mmu:18577 mmu:18578 mmu:18582 mmu:18583 mmu:18584 mmu:18585 mmu:18587 mmu:18588 mmu:207728 mmu:218461 mmu:225600 mmu:238871 mmu:23984 mmu:241489 mmu:242202 mmu:29863 mmu:54611 mmu:78600</Comment>
    <Graphics CenterX="141.79898241873565" CenterY="563.8574623569884" Width="80.0" Height="20.0" ZOrder="34243" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="241489" />
  </DataNode>
  <DataNode TextLabel="Nt5c3" GraphId="cd261" Type="GeneProduct" GroupRef="b56f8">
    <Comment Source="KeggConverter">Original kegg element: gene;192;mmu:103850 mmu:107569 mmu:230718 mmu:23959 mmu:50773 mmu:70881 mmu:76952</Comment>
    <Graphics CenterX="2104.3973483326718" CenterY="868.7660690087237" Width="80.0" Height="20.0" ZOrder="34244" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="107569" />
  </DataNode>
  <DataNode TextLabel="Atic" GraphId="e4fb8" Type="GeneProduct">
    <Comment Source="KeggConverter">Original kegg element: gene;415;mmu:108147</Comment>
    <Graphics CenterX="1921.7541181197255" CenterY="441.33095450490634" Width="80.0" Height="20.0" ZOrder="34246" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="108147" />
  </DataNode>
  <DataNode TextLabel="Polr2d" GraphId="e32ba" Type="GeneProduct" GroupRef="c746a">
    <Comment Source="KeggConverter">Original kegg element: gene;241;mmu:100043714 mmu:100046796 mmu:20016 mmu:20017 mmu:20018 mmu:20019 mmu:20020 mmu:20021 mmu:20022 mmu:218832 mmu:231329 mmu:245841 mmu:26939 mmu:625405 mmu:64424 mmu:66136 mmu:66420 mmu:66491 mmu:67005 mmu:67065 mmu:67486 mmu:67710 mmu:69241 mmu:69833 mmu:69870 mmu:69920 mmu:70408 mmu:70428 mmu:74414 mmu:78929</Comment>
    <Graphics CenterX="204.2166917255112" CenterY="1214.6362204095317" Width="92.46225755421057" Height="25.554043353358804" ZOrder="34247" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="69241" />
  </DataNode>
  <DataNode TextLabel="Itpa" GraphId="f348b" Type="GeneProduct">
    <Comment Source="KeggConverter">Original kegg element: gene;274;mmu:16434</Comment>
    <Graphics CenterX="814.7144992526182" CenterY="1029.3204124547137" Width="80.0" Height="20.0" ZOrder="34248" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="16434" />
  </DataNode>
  <DataNode TextLabel="Pde8a" GraphId="c2542" Type="GeneProduct" GroupRef="e4165">
    <Comment Source="KeggConverter">Original kegg element: gene;245;mmu:110385 mmu:110855 mmu:18573 mmu:18574 mmu:18575 mmu:18576 mmu:18577 mmu:18578 mmu:18582 mmu:18583 mmu:18584 mmu:18585 mmu:18587 mmu:18588 mmu:207728 mmu:218461 mmu:225600 mmu:238871 mmu:23984 mmu:241489 mmu:242202 mmu:29863 mmu:54611 mmu:78600</Comment>
    <Graphics CenterX="141.79898241873565" CenterY="863.8574623569883" Width="80.0" Height="20.0" ZOrder="34249" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="18584" />
  </DataNode>
  <DataNode TextLabel="Gm10774" GraphId="d6343" Type="GeneProduct" GroupRef="c746a">
    <Comment Source="KeggConverter">Original kegg element: gene;241;mmu:100043714 mmu:100046796 mmu:20016 mmu:20017 mmu:20018 mmu:20019 mmu:20020 mmu:20021 mmu:20022 mmu:218832 mmu:231329 mmu:245841 mmu:26939 mmu:625405 mmu:64424 mmu:66136 mmu:66420 mmu:66491 mmu:67005 mmu:67065 mmu:67486 mmu:67710 mmu:69241 mmu:69833 mmu:69870 mmu:69920 mmu:70408 mmu:70428 mmu:74414 mmu:78929</Comment>
    <Graphics CenterX="110.76377692730505" CenterY="1189.829561211628" Width="92.46225755421065" Height="25.554043353358804" ZOrder="34250" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="100043714" />
  </DataNode>
  <DataNode TextLabel="GTP" GraphId="c5338" Type="Metabolite">
    <Graphics CenterX="737.2710997442449" CenterY="792.3258611262988" Width="95.79028132992387" Height="31.951427103969746" ZOrder="34251" FontSize="10" Valign="Middle" Color="0000ff" />
    <Xref Database="KEGG Compound" ID="C00044" />
  </DataNode>
  <DataNode TextLabel="Gda" GraphId="ea110" Type="GeneProduct">
    <Comment Source="KeggConverter">Original kegg element: gene;219;mmu:14544</Comment>
    <Graphics CenterX="1466.5080757031237" CenterY="1231.6479492819233" Width="80.0" Height="20.0" ZOrder="34252" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="14544" />
  </DataNode>
  <DataNode TextLabel="DNA-directed &#xA;RNA polymerases I" GraphId="ccd2d" Type="GeneProduct" GroupRef="afea2">
    <Comment Source="KeggConverter">Original kegg element: gene;168;mmu:100043714 mmu:100046796 mmu:20016 mmu:20017 mmu:20018 mmu:20019 mmu:20020 mmu:20021 mmu:20022 mmu:218832 mmu:231329 mmu:245841 mmu:26939 mmu:625405 mmu:64424 mmu:66136 mmu:66420 mmu:66491 mmu:67005 mmu:67065 mmu:67486 mmu:67710 mmu:69241 mmu:69833 mmu:69870 mmu:69920 mmu:70408 mmu:70428 mmu:74414 mmu:78929</Comment>
    <Graphics CenterX="3295.167103054288" CenterY="599.1702473823411" Width="90.94297214511288" Height="23.59261277206494" ZOrder="34253" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="100046796" />
  </DataNode>
  <DataNode TextLabel="Adss" GraphId="f63ec" Type="GeneProduct" GroupRef="a3040">
    <Comment Source="KeggConverter">Original kegg element: gene;180;mmu:11565 mmu:11566</Comment>
    <Graphics CenterX="2118.639696018409" CenterY="478.4732824427489" Width="80.0" Height="20.0" ZOrder="34254" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="11566" />
  </DataNode>
  <DataNode TextLabel="Pde6g" GraphId="dbe71" Type="GeneProduct" GroupRef="e4165">
    <Comment Source="KeggConverter">Original kegg element: gene;245;mmu:110385 mmu:110855 mmu:18573 mmu:18574 mmu:18575 mmu:18576 mmu:18577 mmu:18578 mmu:18582 mmu:18583 mmu:18584 mmu:18585 mmu:18587 mmu:18588 mmu:207728 mmu:218461 mmu:225600 mmu:238871 mmu:23984 mmu:241489 mmu:242202 mmu:29863 mmu:54611 mmu:78600</Comment>
    <Graphics CenterX="141.79898241873565" CenterY="623.8574623569884" Width="80.0" Height="20.0" ZOrder="34255" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="18588" />
  </DataNode>
  <DataNode TextLabel="Thiamine &#xA;metabolism" GraphId="b96c3" Type="Pathway">
    <Comment Source="KeggConverter">Original kegg element: map;150;path:mmu00730</Comment>
    <Graphics CenterX="1408.5789473684213" CenterY="89.06779661016958" Width="80.31578947368396" Height="37.47368421052616" ZOrder="34256" FontWeight="Bold" FontSize="10" Valign="Middle" Color="14961e" />
    <Xref Database="WikiPathways" ID="WP2185" />
  </DataNode>
  <DataNode TextLabel="Nme7" GraphId="ec5ac" Type="GeneProduct" GroupRef="e70b2">
    <Comment Source="KeggConverter">Original kegg element: gene;293;mmu:171567 mmu:18102 mmu:18103 mmu:54369 mmu:56520 mmu:75533 mmu:79059</Comment>
    <Graphics CenterX="851.9514884233735" CenterY="430.2728682749989" Width="80.0" Height="20.0" ZOrder="34257" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="171567" />
  </DataNode>
  <DataNode TextLabel="Gmpr2" GraphId="ef8b6" Type="GeneProduct" GroupRef="dcc3e">
    <Comment Source="KeggConverter">Original kegg element: gene;200;mmu:105446 mmu:66355</Comment>
    <Graphics CenterX="1663.1688311688313" CenterY="748.5006970430708" Width="80.0" Height="20.0" ZOrder="34258" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="105446" />
  </DataNode>
  <DataNode TextLabel="Deoxyadenosine" GraphId="a7562" Type="Metabolite">
    <Graphics CenterX="3110.0" CenterY="1151.5460574797346" Width="80.00000000000007" Height="19.999999999999922" ZOrder="34259" FontSize="10" Valign="Middle" Color="0000ff" />
    <Xref Database="KEGG Compound" ID="C00559" />
  </DataNode>
  <DataNode TextLabel="Gucy1b2" GraphId="eac69" Type="GeneProduct" GroupRef="e83ec">
    <Comment Source="KeggConverter">Original kegg element: gene;243;mmu:14917 mmu:14918 mmu:14919 mmu:18160 mmu:230103 mmu:234889 mmu:239134 mmu:245650 mmu:54195 mmu:60596</Comment>
    <Graphics CenterX="263.6371674701754" CenterY="815.4877239289058" Width="80.0" Height="20.0" ZOrder="34260" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="239134" />
  </DataNode>
  <DataNode TextLabel="Xanthosine &#xA;5'-phosphate" GraphId="ae74d" Type="Metabolite">
    <Comment>aka XMP</Comment>
    <Graphics CenterX="1670.5974025974024" CenterY="812.0991927095944" Width="79.99999999999989" Height="25.212399653541205" ZOrder="34261" FontSize="10" Valign="Middle" Color="0000ff" />
    <Xref Database="KEGG Compound" ID="C00655" />
  </DataNode>
  <DataNode TextLabel="5'-Phospho&#xA;ribosylglycinamide" GraphId="e8c3b" Type="Metabolite">
    <Graphics CenterX="872.8213166144201" CenterY="234.3593326603263" Width="95.92476489028229" Height="26.645768025078432" ZOrder="34262" FontSize="10" Valign="Middle" Color="0000ff" />
    <Xref Database="KEGG Compound" ID="C03838" />
  </DataNode>
  <DataNode TextLabel="Nme6" GraphId="a2523" Type="GeneProduct" GroupRef="bfdae">
    <Comment Source="KeggConverter">Original kegg element: gene;174;mmu:171567 mmu:18102 mmu:18103 mmu:54369 mmu:56520 mmu:75533 mmu:79059</Comment>
    <Graphics CenterX="3237.1578947368394" CenterY="880.8046387154327" Width="80.0" Height="20.0" ZOrder="34263" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="54369" />
  </DataNode>
  <DataNode TextLabel="Pde8b" GraphId="f587f" Type="GeneProduct" GroupRef="f5806">
    <Comment Source="KeggConverter">Original kegg element: gene;165;mmu:110385 mmu:18573 mmu:18574 mmu:18575 mmu:18576 mmu:18577 mmu:18578 mmu:18583 mmu:18584 mmu:207728 mmu:218461 mmu:238871 mmu:23984 mmu:241489 mmu:29863 mmu:54611</Comment>
    <Graphics CenterX="2713.2557883131203" CenterY="288.09536000597984" Width="80.0" Height="20.0" ZOrder="34264" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="218461" />
  </DataNode>
  <DataNode TextLabel="Znrd1" GraphId="dc1b1" Type="GeneProduct" GroupRef="afea2">
    <Comment Source="KeggConverter">Original kegg element: gene;168;mmu:100043714 mmu:100046796 mmu:20016 mmu:20017 mmu:20018 mmu:20019 mmu:20020 mmu:20021 mmu:20022 mmu:218832 mmu:231329 mmu:245841 mmu:26939 mmu:625405 mmu:64424 mmu:66136 mmu:66420 mmu:66491 mmu:67005 mmu:67065 mmu:67486 mmu:67710 mmu:69241 mmu:69833 mmu:69870 mmu:69920 mmu:70408 mmu:70428 mmu:74414 mmu:78929</Comment>
    <Graphics CenterX="3204.224130909176" CenterY="669.9480856985358" Width="90.94297214511298" Height="23.592612772064896" ZOrder="34265" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="66136" />
  </DataNode>
  <DataNode TextLabel="Nme2" GraphId="ba204" Type="GeneProduct" GroupRef="e70b2">
    <Comment Source="KeggConverter">Original kegg element: gene;293;mmu:171567 mmu:18102 mmu:18103 mmu:54369 mmu:56520 mmu:75533 mmu:79059</Comment>
    <Graphics CenterX="931.9514884233737" CenterY="370.272868274999" Width="80.0" Height="20.0" ZOrder="34266" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="18103" />
  </DataNode>
  <DataNode TextLabel="Gucy1b3" GraphId="c364e" Type="GeneProduct" GroupRef="e83ec">
    <Comment Source="KeggConverter">Original kegg element: gene;243;mmu:14917 mmu:14918 mmu:14919 mmu:18160 mmu:230103 mmu:234889 mmu:239134 mmu:245650 mmu:54195 mmu:60596</Comment>
    <Graphics CenterX="263.6371674701754" CenterY="835.4877239289057" Width="80.0" Height="20.0" ZOrder="34268" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="54195" />
  </DataNode>
  <DataNode TextLabel="Nme4" GraphId="a60a8" Type="GeneProduct" GroupRef="d2b7a">
    <Comment Source="KeggConverter">Original kegg element: gene;198;mmu:171567 mmu:18102 mmu:18103 mmu:54369 mmu:56520 mmu:75533 mmu:79059</Comment>
    <Graphics CenterX="1557.728960305232" CenterY="476.5266710690438" Width="80.0" Height="20.0" ZOrder="34269" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="56520" />
  </DataNode>
  <DataNode TextLabel="Pde7a" GraphId="d940c" Type="GeneProduct" GroupRef="e4165">
    <Comment Source="KeggConverter">Original kegg element: gene;245;mmu:110385 mmu:110855 mmu:18573 mmu:18574 mmu:18575 mmu:18576 mmu:18577 mmu:18578 mmu:18582 mmu:18583 mmu:18584 mmu:18585 mmu:18587 mmu:18588 mmu:207728 mmu:218461 mmu:225600 mmu:238871 mmu:23984 mmu:241489 mmu:242202 mmu:29863 mmu:54611 mmu:78600</Comment>
    <Graphics CenterX="141.79898241873565" CenterY="663.8574623569884" Width="80.0" Height="20.0" ZOrder="34270" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="18583" />
  </DataNode>
  <DataNode TextLabel="Prune" GraphId="c18f6" Type="GeneProduct">
    <Comment Source="KeggConverter">Original kegg element: gene;231;mmu:229589</Comment>
    <Graphics CenterX="660.8235294117634" CenterY="462.7532186050548" Width="80.0" Height="20.0" ZOrder="34271" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="229589" />
  </DataNode>
  <DataNode TextLabel="Pnp2" GraphId="d43e1" Type="GeneProduct" GroupRef="cb412">
    <Comment Source="KeggConverter">Original kegg element: gene;218;mmu:18950 mmu:667034</Comment>
    <Graphics CenterX="967.9653679653674" CenterY="1291.6955022378743" Width="80.0" Height="20.0" ZOrder="34272" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="667034" />
  </DataNode>
  <DataNode TextLabel="Gucy1a2" GraphId="ab195" Type="GeneProduct" GroupRef="e83ec">
    <Comment Source="KeggConverter">Original kegg element: gene;243;mmu:14917 mmu:14918 mmu:14919 mmu:18160 mmu:230103 mmu:234889 mmu:239134 mmu:245650 mmu:54195 mmu:60596</Comment>
    <Graphics CenterX="263.6371674701754" CenterY="695.4877239289053" Width="80.0" Height="20.0" ZOrder="34273" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="234889" />
  </DataNode>
  <DataNode TextLabel="Pde1c" GraphId="a6c61" Type="GeneProduct" GroupRef="e4165">
    <Comment Source="KeggConverter">Original kegg element: gene;245;mmu:110385 mmu:110855 mmu:18573 mmu:18574 mmu:18575 mmu:18576 mmu:18577 mmu:18578 mmu:18582 mmu:18583 mmu:18584 mmu:18585 mmu:18587 mmu:18588 mmu:207728 mmu:218461 mmu:225600 mmu:238871 mmu:23984 mmu:241489 mmu:242202 mmu:29863 mmu:54611 mmu:78600</Comment>
    <Graphics CenterX="141.79898241873565" CenterY="803.8574623569884" Width="80.0" Height="20.0" ZOrder="34274" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="18575" />
  </DataNode>
  <DataNode TextLabel="Gucy2f" GraphId="f8ba0" Type="GeneProduct" GroupRef="e83ec">
    <Comment Source="KeggConverter">Original kegg element: gene;243;mmu:14917 mmu:14918 mmu:14919 mmu:18160 mmu:230103 mmu:234889 mmu:239134 mmu:245650 mmu:54195 mmu:60596</Comment>
    <Graphics CenterX="263.6371674701754" CenterY="675.4877239289054" Width="80.0" Height="20.0" ZOrder="34275" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="245650" />
  </DataNode>
  <DataNode TextLabel="Rrm1" GraphId="dbc23" Type="GeneProduct" GroupRef="e684f">
    <Comment Source="KeggConverter">Original kegg element: gene;176;mmu:20133 mmu:20135 mmu:382985</Comment>
    <Graphics CenterX="2808.4716924156696" CenterY="890.617680039127" Width="80.0" Height="20.0" ZOrder="34276" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="20133" />
  </DataNode>
  <DataNode TextLabel="1-(5'-Phosphoribosyl)-5-&#xA;amino-4-imidazolecarboxamide" GraphId="ef8a3" Type="Metabolite">
    <Graphics CenterX="2019.4736842105272" CenterY="234.21356463524796" Width="149.0" Height="31.0" ZOrder="34277" FontSize="10" Valign="Middle" Color="0000ff" />
    <Xref Database="KEGG Compound" ID="C04677" />
  </DataNode>
  <DataNode TextLabel="Aprt" GraphId="c69a9" Type="GeneProduct">
    <Comment Source="KeggConverter">Original kegg element: gene;300;mmu:11821</Comment>
    <Graphics CenterX="1101.0562770562783" CenterY="1027.8167143590863" Width="53.97402597402734" Height="20.0" ZOrder="34278" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="11821" />
  </DataNode>
  <DataNode TextLabel="Polr1d" GraphId="e10cb" Type="GeneProduct" GroupRef="c746a">
    <Comment Source="KeggConverter">Original kegg element: gene;241;mmu:100043714 mmu:100046796 mmu:20016 mmu:20017 mmu:20018 mmu:20019 mmu:20020 mmu:20021 mmu:20022 mmu:218832 mmu:231329 mmu:245841 mmu:26939 mmu:625405 mmu:64424 mmu:66136 mmu:66420 mmu:66491 mmu:67005 mmu:67065 mmu:67486 mmu:67710 mmu:69241 mmu:69833 mmu:69870 mmu:69920 mmu:70408 mmu:70428 mmu:74414 mmu:78929</Comment>
    <Graphics CenterX="110.76377692730505" CenterY="1240.9376479183459" Width="92.46225755421065" Height="25.554043353358804" ZOrder="34279" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="20018" />
  </DataNode>
  <DataNode TextLabel="Nudt2" GraphId="e903a" Type="GeneProduct">
    <Comment Source="KeggConverter">Original kegg element: gene;275;mmu:66401</Comment>
    <Graphics CenterX="1513.2361785796902" CenterY="929.2480616377634" Width="80.0" Height="20.0" ZOrder="34280" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="66401" />
  </DataNode>
  <DataNode TextLabel="Entpd4" GraphId="bb933" Type="GeneProduct" GroupRef="fc1ac">
    <Comment Source="KeggConverter">Original kegg element: gene;303;mmu:12497 mmu:12499 mmu:67464 mmu:76025</Comment>
    <Graphics CenterX="1882.5454545454545" CenterY="689.1587057010789" Width="80.0" Height="20.0" ZOrder="34281" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="67464" />
  </DataNode>
  <DataNode TextLabel="Nme4" GraphId="a7168" Type="GeneProduct" GroupRef="cf79b">
    <Comment Source="KeggConverter">Original kegg element: gene;175;mmu:171567 mmu:18102 mmu:18103 mmu:54369 mmu:56520 mmu:75533 mmu:79059</Comment>
    <Graphics CenterX="3021.409040793826" CenterY="1012.2706632033339" Width="80.0" Height="20.0" ZOrder="34282" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="56520" />
  </DataNode>
  <DataNode TextLabel="Allc" GraphId="dede5" Type="GeneProduct">
    <Comment Source="KeggConverter">Original kegg element: gene;221;mmu:94041</Comment>
    <Graphics CenterX="2290.6233766233754" CenterY="1424.656541198914" Width="80.0" Height="20.0" ZOrder="34283" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="94041" />
  </DataNode>
  <DataNode TextLabel="Nme2" GraphId="a263b" Type="GeneProduct" GroupRef="cf79b">
    <Comment Source="KeggConverter">Original kegg element: gene;175;mmu:171567 mmu:18102 mmu:18103 mmu:54369 mmu:56520 mmu:75533 mmu:79059</Comment>
    <Graphics CenterX="3021.409040793826" CenterY="992.2706632033339" Width="80.0" Height="20.0" ZOrder="34284" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="18103" />
  </DataNode>
  <DataNode TextLabel="Entpd8" GraphId="ef643" Type="GeneProduct" GroupRef="bd17f">
    <Comment Source="KeggConverter">Original kegg element: gene;199;mmu:12495 mmu:215446 mmu:72090</Comment>
    <Graphics CenterX="1630.1744808863455" CenterY="687.5180864333413" Width="80.0" Height="20.0" ZOrder="34285" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="72090" />
  </DataNode>
  <DataNode TextLabel="Pde8a" GraphId="b1635" Type="GeneProduct" GroupRef="f5806">
    <Comment Source="KeggConverter">Original kegg element: gene;165;mmu:110385 mmu:18573 mmu:18574 mmu:18575 mmu:18576 mmu:18577 mmu:18578 mmu:18583 mmu:18584 mmu:207728 mmu:218461 mmu:238871 mmu:23984 mmu:241489 mmu:29863 mmu:54611</Comment>
    <Graphics CenterX="2713.2557883131203" CenterY="268.09536000597984" Width="80.0" Height="20.0" ZOrder="34286" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="18584" />
  </DataNode>
  <DataNode TextLabel="Nt5m" GraphId="f3180" Type="GeneProduct" GroupRef="e79b1">
    <Comment Source="KeggConverter">Original kegg element: gene;186;mmu:103850 mmu:107569 mmu:230718 mmu:23959 mmu:50773 mmu:70881 mmu:76952</Comment>
    <Graphics CenterX="2909.0679910424597" CenterY="1149.831765438452" Width="80.0" Height="20.0" ZOrder="34287" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="103850" />
  </DataNode>
  <DataNode TextLabel="Rrm2" GraphId="eb13e" Type="GeneProduct" GroupRef="e1c60">
    <Comment Source="KeggConverter">Original kegg element: gene;133;mmu:20133 mmu:20135 mmu:382985</Comment>
    <Graphics CenterX="1074.9515616523279" CenterY="861.5401673766575" Width="80.0" Height="20.0" ZOrder="34288" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="20135" />
  </DataNode>
  <DataNode TextLabel="dADP" GraphId="eed20" Type="Metabolite">
    <Graphics CenterX="2728.0" CenterY="942.0677966101696" Width="79.99999999999994" Height="25.660874519299295" ZOrder="34289" FontSize="10" Valign="Middle" Color="0000ff" />
    <Xref Database="KEGG Compound" ID="C00206" />
  </DataNode>
  <DataNode TextLabel="Polr3f" GraphId="e494e" Type="GeneProduct" GroupRef="c746a">
    <Comment Source="KeggConverter">Original kegg element: gene;241;mmu:100043714 mmu:100046796 mmu:20016 mmu:20017 mmu:20018 mmu:20019 mmu:20020 mmu:20021 mmu:20022 mmu:218832 mmu:231329 mmu:245841 mmu:26939 mmu:625405 mmu:64424 mmu:66136 mmu:66420 mmu:66491 mmu:67005 mmu:67065 mmu:67486 mmu:67710 mmu:69241 mmu:69833 mmu:69870 mmu:69920 mmu:70408 mmu:70428 mmu:74414 mmu:78929</Comment>
    <Graphics CenterX="204.2166917255112" CenterY="1265.7443071162497" Width="92.46225755421057" Height="25.554043353358804" ZOrder="34290" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="70408" />
  </DataNode>
  <DataNode TextLabel="Paics" GraphId="af816" Type="GeneProduct">
    <Comment Source="KeggConverter">Original kegg element: gene;162;mmu:67054</Comment>
    <Graphics CenterX="1490.783699059561" CenterY="186.40008501142376" Width="80.0" Height="20.0" ZOrder="34291" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="67054" />
  </DataNode>
  <DataNode TextLabel="Ada" GraphId="c9cd9" Type="GeneProduct">
    <Comment Source="KeggConverter">Original kegg element: gene;187;mmu:11486</Comment>
    <Graphics CenterX="3235.0348698920207" CenterY="1238.1982375977536" Width="80.0" Height="20.0" ZOrder="34292" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="11486" />
  </DataNode>
  <DataNode TextLabel="Nt5e" GraphId="f9cbe" Type="GeneProduct" GroupRef="b56f8">
    <Comment Source="KeggConverter">Original kegg element: gene;192;mmu:103850 mmu:107569 mmu:230718 mmu:23959 mmu:50773 mmu:70881 mmu:76952</Comment>
    <Graphics CenterX="2104.3973483326718" CenterY="848.7660690087237" Width="80.0" Height="20.0" ZOrder="34293" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="23959" />
  </DataNode>
  <DataNode TextLabel="Pole" GraphId="f429c" Type="GeneProduct" GroupRef="fc208">
    <Comment Source="KeggConverter">Original kegg element: gene;244;mmu:18968 mmu:18969 mmu:18971 mmu:18972 mmu:18973 mmu:18974 mmu:19075 mmu:19076 mmu:59001 mmu:66979 mmu:67967 mmu:69745</Comment>
    <Graphics CenterX="641.1601255886964" CenterY="1035.9422079131537" Width="80.0" Height="20.0" ZOrder="34294" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="18973" />
  </DataNode>
  <DataNode TextLabel="Polr3c" GraphId="c98d2" Type="GeneProduct" GroupRef="afea2">
    <Comment Source="KeggConverter">Original kegg element: gene;168;mmu:100043714 mmu:100046796 mmu:20016 mmu:20017 mmu:20018 mmu:20019 mmu:20020 mmu:20021 mmu:20022 mmu:218832 mmu:231329 mmu:245841 mmu:26939 mmu:625405 mmu:64424 mmu:66136 mmu:66420 mmu:66491 mmu:67005 mmu:67065 mmu:67486 mmu:67710 mmu:69241 mmu:69833 mmu:69870 mmu:69920 mmu:70408 mmu:70428 mmu:74414 mmu:78929</Comment>
    <Graphics CenterX="3386.1100751994018" CenterY="717.1333112426655" Width="90.94297214511298" Height="23.592612772064896" ZOrder="34296" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="74414" />
  </DataNode>
  <DataNode TextLabel="XTP" GraphId="a241f" Type="Metabolite">
    <Graphics CenterX="1582.0" CenterY="879.8717169103386" Width="80.0" Height="20.0" ZOrder="34297" FontSize="10" Valign="Middle" Color="0000ff" />
    <Xref Database="KEGG Compound" ID="C00700" />
  </DataNode>
  <DataNode TextLabel="Aprt" GraphId="f7182" Type="GeneProduct">
    <Comment Source="KeggConverter">Original kegg element: gene;184;mmu:11821</Comment>
    <Graphics CenterX="2603.321712752725" CenterY="956.4050090372377" Width="80.0" Height="20.0" ZOrder="34298" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="11821" />
  </DataNode>
  <DataNode TextLabel="Polr2l" GraphId="bf3ee" Type="GeneProduct" GroupRef="c746a">
    <Comment Source="KeggConverter">Original kegg element: gene;241;mmu:100043714 mmu:100046796 mmu:20016 mmu:20017 mmu:20018 mmu:20019 mmu:20020 mmu:20021 mmu:20022 mmu:218832 mmu:231329 mmu:245841 mmu:26939 mmu:625405 mmu:64424 mmu:66136 mmu:66420 mmu:66491 mmu:67005 mmu:67065 mmu:67486 mmu:67710 mmu:69241 mmu:69833 mmu:69870 mmu:69920 mmu:70408 mmu:70428 mmu:74414 mmu:78929</Comment>
    <Graphics CenterX="19.048068185003256" CenterY="1215.167266171073" Width="92.46225755421057" Height="25.554043353358804" ZOrder="34299" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="66491" />
  </DataNode>
  <DataNode TextLabel="Pole4" GraphId="b580e" Type="GeneProduct" GroupRef="d5f1e">
    <Comment Source="KeggConverter">Original kegg element: gene;170;mmu:18968 mmu:18969 mmu:18971 mmu:18972 mmu:18973 mmu:18974 mmu:19075 mmu:19076 mmu:59001 mmu:66979 mmu:67967 mmu:69745</Comment>
    <Graphics CenterX="3288.304299889746" CenterY="1029.2938164558145" Width="80.0" Height="20.0" ZOrder="34300" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="66979" />
  </DataNode>
  <DataNode TextLabel="GDP" GraphId="f560c" Type="Metabolite">
    <Graphics CenterX="1000.0" CenterY="792.3258611262988" Width="80.0" Height="20.0" ZOrder="34301" FontSize="10" Valign="Middle" Color="0000ff" />
    <Xref Database="KEGG Compound" ID="C00035" />
  </DataNode>
  <DataNode TextLabel="Adcy8" GraphId="d7193" Type="GeneProduct" GroupRef="ae4c5">
    <Comment Source="KeggConverter">Original kegg element: gene;297;mmu:104110 mmu:104111 mmu:11512 mmu:11513 mmu:11514 mmu:11515 mmu:210044 mmu:224129 mmu:271639 mmu:432530</Comment>
    <Graphics CenterX="369.7182662538706" CenterY="793.7456805784034" Width="80.0" Height="20.0" ZOrder="34302" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="11514" />
  </DataNode>
  <DataNode TextLabel="Pde3a" GraphId="e9e01" Type="GeneProduct" GroupRef="f5806">
    <Comment Source="KeggConverter">Original kegg element: gene;165;mmu:110385 mmu:18573 mmu:18574 mmu:18575 mmu:18576 mmu:18577 mmu:18578 mmu:18583 mmu:18584 mmu:207728 mmu:218461 mmu:238871 mmu:23984 mmu:241489 mmu:29863 mmu:54611</Comment>
    <Graphics CenterX="2633.2557883131203" CenterY="188.09536000597984" Width="80.0" Height="20.0" ZOrder="34303" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="54611" />
  </DataNode>
  <DataNode TextLabel="Gart" GraphId="dda82" Type="GeneProduct">
    <Comment Source="KeggConverter">Original kegg element: gene;156;mmu:14450</Comment>
    <Graphics CenterX="778.1630094043875" CenterY="186.40008501142376" Width="80.0" Height="20.0" ZOrder="34304" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="14450" />
  </DataNode>
  <DataNode TextLabel="Nt5c1a" GraphId="db533" Type="GeneProduct" GroupRef="b56f8">
    <Comment Source="KeggConverter">Original kegg element: gene;192;mmu:103850 mmu:107569 mmu:230718 mmu:23959 mmu:50773 mmu:70881 mmu:76952</Comment>
    <Graphics CenterX="2104.3973483326718" CenterY="908.7660690087239" Width="80.0" Height="20.0" ZOrder="34305" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="230718" />
  </DataNode>
  <DataNode TextLabel="Pold2" GraphId="cf57d" Type="GeneProduct" GroupRef="d5f1e">
    <Comment Source="KeggConverter">Original kegg element: gene;170;mmu:18968 mmu:18969 mmu:18971 mmu:18972 mmu:18973 mmu:18974 mmu:19075 mmu:19076 mmu:59001 mmu:66979 mmu:67967 mmu:69745</Comment>
    <Graphics CenterX="3288.304299889746" CenterY="1089.2938164558145" Width="80.0" Height="20.0" ZOrder="34306" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="18972" />
  </DataNode>
  <DataNode TextLabel="ec:3.5.2.-" GraphId="ae907" Type="GeneProduct">
    <Graphics CenterX="1234.0" CenterY="1326.0677966101696" Width="80.0" Height="20.0" ZOrder="34307" FontSize="10" Valign="Middle" />
    <Xref Database="Enzyme Nomenclature" ID="3.5.2.-" />
  </DataNode>
  <DataNode TextLabel="Prim1" GraphId="aec85" Type="GeneProduct" GroupRef="fc208">
    <Comment Source="KeggConverter">Original kegg element: gene;244;mmu:18968 mmu:18969 mmu:18971 mmu:18972 mmu:18973 mmu:18974 mmu:19075 mmu:19076 mmu:59001 mmu:66979 mmu:67967 mmu:69745</Comment>
    <Graphics CenterX="641.1601255886964" CenterY="1055.9422079131537" Width="80.0" Height="20.0" ZOrder="34308" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="19075" />
  </DataNode>
  <DataNode TextLabel="Nt5c2" GraphId="dbbf9" Type="GeneProduct" GroupRef="b56f8">
    <Comment Source="KeggConverter">Original kegg element: gene;192;mmu:103850 mmu:107569 mmu:230718 mmu:23959 mmu:50773 mmu:70881 mmu:76952</Comment>
    <Graphics CenterX="2104.3973483326718" CenterY="948.7660690087241" Width="80.0" Height="20.0" ZOrder="34309" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="76952" />
  </DataNode>
  <DataNode TextLabel="Entpd1" GraphId="eab09" Type="GeneProduct" GroupRef="e2820">
    <Comment Source="KeggConverter">Original kegg element: gene;177;mmu:12495 mmu:215446 mmu:72090</Comment>
    <Graphics CenterX="2613.9496230029104" CenterY="848.5375759478502" Width="80.0" Height="20.0" ZOrder="34310" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="12495" />
  </DataNode>
  <DataNode TextLabel="Pold4" GraphId="ca0b8" Type="GeneProduct" GroupRef="fc208">
    <Comment Source="KeggConverter">Original kegg element: gene;244;mmu:18968 mmu:18969 mmu:18971 mmu:18972 mmu:18973 mmu:18974 mmu:19075 mmu:19076 mmu:59001 mmu:66979 mmu:67967 mmu:69745</Comment>
    <Graphics CenterX="561.0973312401883" CenterY="995.2514700795576" Width="80.0" Height="20.0" ZOrder="34311" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="69745" />
  </DataNode>
  <DataNode TextLabel="Rrm2b" GraphId="a6f03" Type="GeneProduct" GroupRef="e684f">
    <Comment Source="KeggConverter">Original kegg element: gene;176;mmu:20133 mmu:20135 mmu:382985</Comment>
    <Graphics CenterX="2808.4716924156696" CenterY="910.617680039127" Width="80.0" Height="20.0" ZOrder="34312" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="382985" />
  </DataNode>
  <DataNode TextLabel="IMP" GraphId="c17c7" Type="Metabolite">
    <Graphics CenterX="2019.4736842105272" CenterY="792.3258611262988" Width="79.99999999999991" Height="37.05343511450392" ZOrder="34313" FontSize="10" Valign="Middle" Color="0000ff" />
    <Xref Database="KEGG Compound" ID="C00130" />
  </DataNode>
  <DataNode TextLabel="Adenylyl sulfate" GraphId="bb13f" Type="Metabolite">
    <Graphics CenterX="3005.7304299889747" CenterY="192.55732251976156" Width="80.0" Height="20.0" ZOrder="34314" FontSize="10" Valign="Middle" Color="0000ff" />
    <Xref Database="KEGG Compound" ID="C00224" />
  </DataNode>
  <DataNode TextLabel="Adcy5" GraphId="f6fc3" Type="GeneProduct" GroupRef="e3f1d">
    <Comment Source="KeggConverter">Original kegg element: gene;166;mmu:104110 mmu:104111 mmu:11512 mmu:11513 mmu:11514 mmu:11515 mmu:210044 mmu:224129 mmu:271639 mmu:432530</Comment>
    <Graphics CenterX="3525.0385742900316" CenterY="562.0706628646265" Width="80.0" Height="20.0" ZOrder="34315" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="224129" />
  </DataNode>
  <DataNode TextLabel="Pold1" GraphId="a9007" Type="GeneProduct" GroupRef="d5f1e">
    <Comment Source="KeggConverter">Original kegg element: gene;170;mmu:18968 mmu:18969 mmu:18971 mmu:18972 mmu:18973 mmu:18974 mmu:19075 mmu:19076 mmu:59001 mmu:66979 mmu:67967 mmu:69745</Comment>
    <Graphics CenterX="3368.304299889746" CenterY="1029.2938164558145" Width="80.0" Height="20.0" ZOrder="34316" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="18971" />
  </DataNode>
  <DataNode TextLabel="Pnp" GraphId="f60af" Type="GeneProduct" GroupRef="d3d8f">
    <Comment Source="KeggConverter">Original kegg element: gene;240;mmu:18950 mmu:667034</Comment>
    <Graphics CenterX="1424.3117544033569" CenterY="1117.7096458550766" Width="80.0" Height="20.0" ZOrder="34317" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="18950" />
  </DataNode>
  <DataNode TextLabel="Polr2j" GraphId="df7d1" Type="GeneProduct" GroupRef="c746a">
    <Comment Source="KeggConverter">Original kegg element: gene;241;mmu:100043714 mmu:100046796 mmu:20016 mmu:20017 mmu:20018 mmu:20019 mmu:20020 mmu:20021 mmu:20022 mmu:218832 mmu:231329 mmu:245841 mmu:26939 mmu:625405 mmu:64424 mmu:66136 mmu:66420 mmu:66491 mmu:67005 mmu:67065 mmu:67486 mmu:67710 mmu:69241 mmu:69833 mmu:69870 mmu:69920 mmu:70408 mmu:70428 mmu:74414 mmu:78929</Comment>
    <Graphics CenterX="110.76377692730505" CenterY="1292.045734625064" Width="92.46225755421065" Height="25.554043353358804" ZOrder="34318" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="20022" />
  </DataNode>
  <DataNode TextLabel="Pde6d" GraphId="f1679" Type="GeneProduct" GroupRef="e4165">
    <Comment Source="KeggConverter">Original kegg element: gene;245;mmu:110385 mmu:110855 mmu:18573 mmu:18574 mmu:18575 mmu:18576 mmu:18577 mmu:18578 mmu:18582 mmu:18583 mmu:18584 mmu:18585 mmu:18587 mmu:18588 mmu:207728 mmu:218461 mmu:225600 mmu:238871 mmu:23984 mmu:241489 mmu:242202 mmu:29863 mmu:54611 mmu:78600</Comment>
    <Graphics CenterX="141.79898241873565" CenterY="843.8574623569885" Width="80.0" Height="20.0" ZOrder="34319" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="18582" />
  </DataNode>
  <DataNode TextLabel="Nme3" GraphId="ac5e7" Type="GeneProduct" GroupRef="e70b2">
    <Comment Source="KeggConverter">Original kegg element: gene;293;mmu:171567 mmu:18102 mmu:18103 mmu:54369 mmu:56520 mmu:75533 mmu:79059</Comment>
    <Graphics CenterX="851.9514884233735" CenterY="390.2728682749989" Width="80.0" Height="20.0" ZOrder="34320" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="79059" />
  </DataNode>
  <DataNode TextLabel="RNA" GraphId="c7d5c" Type="Metabolite">
    <Graphics CenterX="3459.0209481808165" CenterY="792.3258611262988" Width="80.0" Height="25.66087451929924" ZOrder="34321" FontSize="10" Valign="Middle" Color="0000ff" />
    <Xref Database="KEGG Compound" ID="C00046" />
  </DataNode>
  <DataNode TextLabel="Gmps" GraphId="d42f9" Type="GeneProduct">
    <Comment Source="KeggConverter">Original kegg element: gene;203;mmu:229363</Comment>
    <Graphics CenterX="1422.1139420376091" CenterY="817.95021953076" Width="80.0" Height="20.0" ZOrder="34322" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="229363" />
  </DataNode>
  <DataNode TextLabel="Papss2" GraphId="d94e5" Type="GeneProduct" GroupRef="e7810">
    <Comment Source="KeggConverter">Original kegg element: gene;249;mmu:23971 mmu:23972</Comment>
    <Graphics CenterX="3111.2304299889747" CenterY="123.55732251976164" Width="80.0" Height="20.0" ZOrder="34323" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="23972" />
  </DataNode>
  <DataNode TextLabel="Nme3" GraphId="f7125" Type="GeneProduct" GroupRef="d2b7a">
    <Comment Source="KeggConverter">Original kegg element: gene;198;mmu:171567 mmu:18102 mmu:18103 mmu:54369 mmu:56520 mmu:75533 mmu:79059</Comment>
    <Graphics CenterX="1477.7289603052322" CenterY="476.5266710690438" Width="80.0" Height="20.0" ZOrder="34324" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="79059" />
  </DataNode>
  <DataNode TextLabel="Pde2a" GraphId="f6769" Type="GeneProduct" GroupRef="e4165">
    <Comment Source="KeggConverter">Original kegg element: gene;245;mmu:110385 mmu:110855 mmu:18573 mmu:18574 mmu:18575 mmu:18576 mmu:18577 mmu:18578 mmu:18582 mmu:18583 mmu:18584 mmu:18585 mmu:18587 mmu:18588 mmu:207728 mmu:218461 mmu:225600 mmu:238871 mmu:23984 mmu:241489 mmu:242202 mmu:29863 mmu:54611 mmu:78600</Comment>
    <Graphics CenterX="141.79898241873565" CenterY="903.8574623569881" Width="80.0" Height="20.0" ZOrder="34325" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="207728" />
  </DataNode>
  <DataNode TextLabel="DNA-directed RNA &#xA;polymerases I" GraphId="e8268" Type="GeneProduct" GroupRef="c746a">
    <Comment Source="KeggConverter">Original kegg element: gene;241;mmu:100043714 mmu:100046796 mmu:20016 mmu:20017 mmu:20018 mmu:20019 mmu:20020 mmu:20021 mmu:20022 mmu:218832 mmu:231329 mmu:245841 mmu:26939 mmu:625405 mmu:64424 mmu:66136 mmu:66420 mmu:66491 mmu:67005 mmu:67065 mmu:67486 mmu:67710 mmu:69241 mmu:69833 mmu:69870 mmu:69920 mmu:70408 mmu:70428 mmu:74414 mmu:78929</Comment>
    <Graphics CenterX="110.76377692730465" CenterY="1164.2755178582695" Width="92.4622575542106" Height="25.554043353358654" ZOrder="34326" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="100046796" />
  </DataNode>
  <DataNode TextLabel="Alanine, aspartate &#xA;and glutamate metabolism" GraphId="b8068" Type="Pathway">
    <Comment Source="KeggConverter">Original kegg element: map;147;path:mmu00250</Comment>
    <Graphics CenterX="700.4473684210573" CenterY="89.06779661016958" Width="137.736842105263" Height="29.05263157894734" ZOrder="34327" FontWeight="Bold" FontSize="10" Valign="Middle" Color="14961e" />
    <Xref Database="WikiPathways" ID="WP662" />
  </DataNode>
  <DataNode TextLabel="Ak7" GraphId="dfffc" Type="GeneProduct" GroupRef="b11a0">
    <Comment Source="KeggConverter">Original kegg element: gene;178;mmu:11636 mmu:11637 mmu:11639 mmu:229949 mmu:78801</Comment>
    <Graphics CenterX="2514.2679558011055" CenterY="722.212402846709" Width="80.0" Height="20.0" ZOrder="34328" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="78801" />
  </DataNode>
  <DataNode TextLabel="Urate" GraphId="a516e" Type="Metabolite">
    <Graphics CenterX="1668.0" CenterY="1364.0677966101696" Width="80.0" Height="20.0" ZOrder="34329" FontSize="10" Valign="Middle" Color="0000ff" />
    <Xref Database="KEGG Compound" ID="C00366" />
  </DataNode>
  <DataNode TextLabel="Nme6" GraphId="dff7a" Type="GeneProduct" GroupRef="d2b7a">
    <Comment Source="KeggConverter">Original kegg element: gene;198;mmu:171567 mmu:18102 mmu:18103 mmu:54369 mmu:56520 mmu:75533 mmu:79059</Comment>
    <Graphics CenterX="1557.7289603052322" CenterY="496.5266710690438" Width="80.0" Height="20.0" ZOrder="34330" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="54369" />
  </DataNode>
  <DataNode TextLabel="2-(Formamido)-N1-&#xA;(5'-phosphoribosyl)&#xA;acetamidine" GraphId="cc91f" Type="Metabolite">
    <Graphics CenterX="1221.667711598746" CenterY="234.35933266032634" Width="108.66457680250775" Height="36.03761755485891" ZOrder="34331" FontSize="10" Valign="Middle" Color="0000ff" />
    <Xref Database="KEGG Compound" ID="C04640" />
  </DataNode>
  <DataNode TextLabel="Ak7" GraphId="eccc2" Type="GeneProduct" GroupRef="d54ef">
    <Comment Source="KeggConverter">Original kegg element: gene;285;mmu:11636 mmu:11637 mmu:11639 mmu:229949 mmu:78801</Comment>
    <Graphics CenterX="2601.0373715597634" CenterY="1075.7173004204114" Width="80.0" Height="20.0" ZOrder="34332" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="78801" />
  </DataNode>
  <DataNode TextLabel="Nt5c2" GraphId="e811a" Type="GeneProduct" GroupRef="b3409">
    <Comment Source="KeggConverter">Original kegg element: gene;239;mmu:103850 mmu:107569 mmu:230718 mmu:23959 mmu:50773 mmu:70881 mmu:76952</Comment>
    <Graphics CenterX="881.809523809525" CenterY="1216.3881429305188" Width="80.0" Height="20.0" ZOrder="34333" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="76952" />
  </DataNode>
  <DataNode TextLabel="IDP" GraphId="b949d" Type="Metabolite">
    <Graphics CenterX="1734.0" CenterY="579.4237288135593" Width="80.00000000000007" Height="31.951427103969714" ZOrder="34334" FontSize="10" Valign="Middle" Color="0000ff" />
    <Xref Database="KEGG Compound" ID="C00104" />
  </DataNode>
  <DataNode TextLabel="Papss2" GraphId="c1ae4" Type="GeneProduct" GroupRef="e2a13">
    <Comment Source="KeggConverter">Original kegg element: gene;250;mmu:23971 mmu:23972</Comment>
    <Graphics CenterX="2933.519697934959" CenterY="247.4251263577146" Width="80.0" Height="20.0" ZOrder="34335" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="23972" />
  </DataNode>
  <DataNode TextLabel="Gucy2e" GraphId="edfe9" Type="GeneProduct" GroupRef="e83ec">
    <Comment Source="KeggConverter">Original kegg element: gene;243;mmu:14917 mmu:14918 mmu:14919 mmu:18160 mmu:230103 mmu:234889 mmu:239134 mmu:245650 mmu:54195 mmu:60596</Comment>
    <Graphics CenterX="263.6371674701754" CenterY="775.4877239289057" Width="80.0" Height="20.0" ZOrder="34336" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="14919" />
  </DataNode>
  <DataNode TextLabel="RNA" GraphId="d3a15" Type="Metabolite">
    <Graphics CenterX="602.0" CenterY="624.0677966101696" Width="80.0" Height="20.0" ZOrder="34337" FontSize="10" Valign="Middle" Color="0000ff" />
    <Xref Database="KEGG Compound" ID="C00046" />
  </DataNode>
  <DataNode TextLabel="Entpd8" GraphId="a0c5b" Type="GeneProduct" GroupRef="c6c79">
    <Comment Source="KeggConverter">Original kegg element: gene;197;mmu:12495 mmu:215446 mmu:72090</Comment>
    <Graphics CenterX="1937.956709956711" CenterY="541.5483160906884" Width="80.0" Height="20.0" ZOrder="34338" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="72090" />
  </DataNode>
  <DataNode TextLabel="Adssl1" GraphId="bb475" Type="GeneProduct" GroupRef="a3040">
    <Comment Source="KeggConverter">Original kegg element: gene;180;mmu:11565 mmu:11566</Comment>
    <Graphics CenterX="2118.639696018409" CenterY="498.4732824427489" Width="80.0" Height="20.0" ZOrder="34339" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="11565" />
  </DataNode>
  <DataNode TextLabel="Nme1" GraphId="e2eb5" Type="GeneProduct" GroupRef="bfdae">
    <Comment Source="KeggConverter">Original kegg element: gene;174;mmu:171567 mmu:18102 mmu:18103 mmu:54369 mmu:56520 mmu:75533 mmu:79059</Comment>
    <Graphics CenterX="3157.1578947368403" CenterY="840.8046387154327" Width="80.0" Height="20.0" ZOrder="34340" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="18102" />
  </DataNode>
  <DataNode TextLabel="Adcy9" GraphId="f2fc5" Type="GeneProduct" GroupRef="e3f1d">
    <Comment Source="KeggConverter">Original kegg element: gene;166;mmu:104110 mmu:104111 mmu:11512 mmu:11513 mmu:11514 mmu:11515 mmu:210044 mmu:224129 mmu:271639 mmu:432530</Comment>
    <Graphics CenterX="3525.0385742900316" CenterY="582.0706628646263" Width="80.0" Height="20.0" ZOrder="34341" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="11515" />
  </DataNode>
  <DataNode TextLabel="ATP" GraphId="f3e72" Type="Metabolite">
    <Graphics CenterX="3053.0476190476193" CenterY="792.3258611262987" Width="79.99999999999984" Height="25.660874519299252" ZOrder="34342" FontSize="10" Valign="Middle" Color="0000ff" />
    <Xref Database="KEGG Compound" ID="C00002" />
  </DataNode>
  <DataNode TextLabel="Aprt" GraphId="f4116" Type="GeneProduct">
    <Comment Source="KeggConverter">Original kegg element: gene;302;mmu:11821</Comment>
    <Graphics CenterX="2129.0" CenterY="186.40008501142376" Width="80.0" Height="20.0" ZOrder="34343" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="11821" />
  </DataNode>
  <DataNode TextLabel="5-Phosphoribo&#xA;sylamine" GraphId="c1d71" Type="Metabolite">
    <Graphics CenterX="700.4473684210574" CenterY="234.3593326603263" Width="86.06896551724154" Height="26.633228840125465" ZOrder="34344" FontSize="10" Valign="Middle" Color="0000ff" />
    <Xref Database="KEGG Compound" ID="C03090" />
  </DataNode>
  <DataNode TextLabel="Pold3" GraphId="fe566" Type="GeneProduct" GroupRef="fc208">
    <Comment Source="KeggConverter">Original kegg element: gene;244;mmu:18968 mmu:18969 mmu:18971 mmu:18972 mmu:18973 mmu:18974 mmu:19075 mmu:19076 mmu:59001 mmu:66979 mmu:67967 mmu:69745</Comment>
    <Graphics CenterX="641.1601255886964" CenterY="1095.9422079131537" Width="80.0" Height="20.0" ZOrder="34345" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="67967" />
  </DataNode>
  <DataNode TextLabel="Rrm2" GraphId="cddc5" Type="GeneProduct" GroupRef="e684f">
    <Comment Source="KeggConverter">Original kegg element: gene;176;mmu:20133 mmu:20135 mmu:382985</Comment>
    <Graphics CenterX="2808.4716924156696" CenterY="870.617680039127" Width="80.0" Height="20.0" ZOrder="34346" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="20135" />
  </DataNode>
  <DataNode TextLabel="Hprt" GraphId="bf4ac" Type="GeneProduct">
    <Comment Source="KeggConverter">Original kegg element: gene;206;mmu:15452</Comment>
    <Graphics CenterX="1968.501002004009" CenterY="991.1619849869251" Width="35.00200400801805" Height="20.0" ZOrder="34347" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="15452" />
  </DataNode>
  <DataNode TextLabel="Gm13015" GraphId="b057b" Type="GeneProduct" GroupRef="afea2">
    <Comment Source="KeggConverter">Original kegg element: gene;168;mmu:100043714 mmu:100046796 mmu:20016 mmu:20017 mmu:20018 mmu:20019 mmu:20020 mmu:20021 mmu:20022 mmu:218832 mmu:231329 mmu:245841 mmu:26939 mmu:625405 mmu:64424 mmu:66136 mmu:66420 mmu:66491 mmu:67005 mmu:67065 mmu:67486 mmu:67710 mmu:69241 mmu:69833 mmu:69870 mmu:69920 mmu:70408 mmu:70428 mmu:74414 mmu:78929</Comment>
    <Graphics CenterX="3204.224130909176" CenterY="693.5406984706007" Width="90.94297214511298" Height="23.592612772064896" ZOrder="34348" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="625405" />
  </DataNode>
  <DataNode TextLabel="Gart" GraphId="ce1d7" Type="GeneProduct">
    <Comment Source="KeggConverter">Original kegg element: gene;157;mmu:14450</Comment>
    <Graphics CenterX="950.9467084639491" CenterY="186.40008501142376" Width="80.0" Height="20.0" ZOrder="34349" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="14450" />
  </DataNode>
  <DataNode TextLabel="Polr1b" GraphId="a3840" Type="GeneProduct" GroupRef="afea2">
    <Comment Source="KeggConverter">Original kegg element: gene;168;mmu:100043714 mmu:100046796 mmu:20016 mmu:20017 mmu:20018 mmu:20019 mmu:20020 mmu:20021 mmu:20022 mmu:218832 mmu:231329 mmu:245841 mmu:26939 mmu:625405 mmu:64424 mmu:66136 mmu:66420 mmu:66491 mmu:67005 mmu:67065 mmu:67486 mmu:67710 mmu:69241 mmu:69833 mmu:69870 mmu:69920 mmu:70408 mmu:70428 mmu:74414 mmu:78929</Comment>
    <Graphics CenterX="3295.1671030542884" CenterY="575.5776346102762" Width="90.94297214511298" Height="23.592612772064896" ZOrder="34350" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="20017" />
  </DataNode>
  <DataNode TextLabel="Entpd3" GraphId="a7766" Type="GeneProduct" GroupRef="c0020">
    <Comment Source="KeggConverter">Original kegg element: gene;204;mmu:12495 mmu:215446 mmu:72090</Comment>
    <Graphics CenterX="1051.6010230179043" CenterY="645.1163899605533" Width="80.0" Height="20.0" ZOrder="34351" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="215446" />
  </DataNode>
  <DataNode TextLabel="Adsl" GraphId="fd2c0" Type="GeneProduct">
    <Comment Source="KeggConverter">Original kegg element: gene;160;mmu:11564</Comment>
    <Graphics CenterX="1924.0" CenterY="186.40008501142376" Width="80.0" Height="20.0" ZOrder="34352" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="11564" />
  </DataNode>
  <DataNode TextLabel="Uox" GraphId="c0162" Type="GeneProduct">
    <Comment Source="KeggConverter">Original kegg element: gene;223;mmu:22262</Comment>
    <Graphics CenterX="1588.0173160173172" CenterY="1416.1284026707738" Width="80.0" Height="20.0" ZOrder="34353" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="22262" />
  </DataNode>
  <DataNode TextLabel="Guk1" GraphId="d8362" Type="GeneProduct">
    <Comment Source="KeggConverter">Original kegg element: gene;217;mmu:14923</Comment>
    <Graphics CenterX="1095.0792838874695" CenterY="820.8913260219323" Width="80.0" Height="20.0" ZOrder="34354" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="14923" />
  </DataNode>
  <DataNode TextLabel="(S)(+)-Allantoin" GraphId="a0038" Type="Metabolite">
    <Graphics CenterX="2002.0" CenterY="1496.0297894196221" Width="80.0" Height="20.0" ZOrder="34355" FontSize="10" Valign="Middle" Color="0000ff" />
    <Xref Database="KEGG Compound" ID="C02350" />
  </DataNode>
  <DataNode TextLabel="Nt5m" GraphId="ae2a9" Type="GeneProduct" GroupRef="bad2e">
    <Comment Source="KeggConverter">Original kegg element: gene;182;mmu:103850 mmu:107569 mmu:230718 mmu:23959 mmu:50773 mmu:70881 mmu:76952</Comment>
    <Graphics CenterX="2495.9226519337017" CenterY="902.8598558668042" Width="80.0" Height="20.0" ZOrder="34356" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="103850" />
  </DataNode>
  <DataNode TextLabel="Ak1" GraphId="c2018" Type="GeneProduct" GroupRef="d54ef">
    <Comment Source="KeggConverter">Original kegg element: gene;285;mmu:11636 mmu:11637 mmu:11639 mmu:229949 mmu:78801</Comment>
    <Graphics CenterX="2601.0373715597634" CenterY="1035.7173004204114" Width="80.0" Height="20.0" ZOrder="34357" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="11636" />
  </DataNode>
  <DataNode TextLabel="Polr2j" GraphId="d1969" Type="GeneProduct" GroupRef="afea2">
    <Comment Source="KeggConverter">Original kegg element: gene;168;mmu:100043714 mmu:100046796 mmu:20016 mmu:20017 mmu:20018 mmu:20019 mmu:20020 mmu:20021 mmu:20022 mmu:218832 mmu:231329 mmu:245841 mmu:26939 mmu:625405 mmu:64424 mmu:66136 mmu:66420 mmu:66491 mmu:67005 mmu:67065 mmu:67486 mmu:67710 mmu:69241 mmu:69833 mmu:69870 mmu:69920 mmu:70408 mmu:70428 mmu:74414 mmu:78929</Comment>
    <Graphics CenterX="3295.1671030542884" CenterY="717.1333112426655" Width="90.94297214511298" Height="23.592612772064896" ZOrder="34358" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="20022" />
  </DataNode>
  <DataNode TextLabel="Pklr" GraphId="a163e" Type="GeneProduct" GroupRef="cb381">
    <Comment Source="KeggConverter">Original kegg element: gene;298;mmu:18746 mmu:18770</Comment>
    <Graphics CenterX="843.1764705882362" CenterY="737.055008886383" Width="80.0" Height="20.0" ZOrder="34359" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="18770" />
  </DataNode>
  <DataNode TextLabel="Polr1d" GraphId="c83d1" Type="GeneProduct" GroupRef="afea2">
    <Comment Source="KeggConverter">Original kegg element: gene;168;mmu:100043714 mmu:100046796 mmu:20016 mmu:20017 mmu:20018 mmu:20019 mmu:20020 mmu:20021 mmu:20022 mmu:218832 mmu:231329 mmu:245841 mmu:26939 mmu:625405 mmu:64424 mmu:66136 mmu:66420 mmu:66491 mmu:67005 mmu:67065 mmu:67486 mmu:67710 mmu:69241 mmu:69833 mmu:69870 mmu:69920 mmu:70408 mmu:70428 mmu:74414 mmu:78929</Comment>
    <Graphics CenterX="3295.1671030542884" CenterY="669.9480856985358" Width="90.94297214511298" Height="23.592612772064896" ZOrder="34360" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="20018" />
  </DataNode>
  <DataNode TextLabel="Gucy1a3" GraphId="e3b50" Type="GeneProduct" GroupRef="e83ec">
    <Comment Source="KeggConverter">Original kegg element: gene;243;mmu:14917 mmu:14918 mmu:14919 mmu:18160 mmu:230103 mmu:234889 mmu:239134 mmu:245650 mmu:54195 mmu:60596</Comment>
    <Graphics CenterX="263.6371674701754" CenterY="655.4877239289054" Width="80.0" Height="20.0" ZOrder="34361" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="60596" />
  </DataNode>
  <DataNode TextLabel="Polr3g" GraphId="db9d7" Type="GeneProduct" GroupRef="c746a">
    <Comment Source="KeggConverter">Original kegg element: gene;241;mmu:100043714 mmu:100046796 mmu:20016 mmu:20017 mmu:20018 mmu:20019 mmu:20020 mmu:20021 mmu:20022 mmu:218832 mmu:231329 mmu:245841 mmu:26939 mmu:625405 mmu:64424 mmu:66136 mmu:66420 mmu:66491 mmu:67005 mmu:67065 mmu:67486 mmu:67710 mmu:69241 mmu:69833 mmu:69870 mmu:69920 mmu:70408 mmu:70428 mmu:74414 mmu:78929</Comment>
    <Graphics CenterX="204.2166917255112" CenterY="1189.082177056173" Width="92.46225755421057" Height="25.554043353358804" ZOrder="34362" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="67486" />
  </DataNode>
  <DataNode TextLabel="Polr2d" GraphId="b82c1" Type="GeneProduct" GroupRef="afea2">
    <Comment Source="KeggConverter">Original kegg element: gene;168;mmu:100043714 mmu:100046796 mmu:20016 mmu:20017 mmu:20018 mmu:20019 mmu:20020 mmu:20021 mmu:20022 mmu:218832 mmu:231329 mmu:245841 mmu:26939 mmu:625405 mmu:64424 mmu:66136 mmu:66420 mmu:66491 mmu:67005 mmu:67065 mmu:67486 mmu:67710 mmu:69241 mmu:69833 mmu:69870 mmu:69920 mmu:70408 mmu:70428 mmu:74414 mmu:78929</Comment>
    <Graphics CenterX="3386.1100751994018" CenterY="646.3554729264708" Width="90.94297214511298" Height="23.592612772064896" ZOrder="34363" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="69241" />
  </DataNode>
  <DataNode TextLabel="Ada" GraphId="be87b" Type="GeneProduct">
    <Comment Source="KeggConverter">Original kegg element: gene;193;mmu:11486</Comment>
    <Graphics CenterX="2166.0" CenterY="990.0677966101696" Width="80.0" Height="20.0" ZOrder="34364" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="11486" />
  </DataNode>
  <DataNode TextLabel="Nt5e" GraphId="ef457" Type="GeneProduct" GroupRef="b3409">
    <Comment Source="KeggConverter">Original kegg element: gene;239;mmu:103850 mmu:107569 mmu:230718 mmu:23959 mmu:50773 mmu:70881 mmu:76952</Comment>
    <Graphics CenterX="801.8095238095249" CenterY="1196.3881429305188" Width="80.0" Height="20.0" ZOrder="34365" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="23959" />
  </DataNode>
  <DataNode TextLabel="Nme2" GraphId="c07fe" Type="GeneProduct" GroupRef="bfdae">
    <Comment Source="KeggConverter">Original kegg element: gene;174;mmu:171567 mmu:18102 mmu:18103 mmu:54369 mmu:56520 mmu:75533 mmu:79059</Comment>
    <Graphics CenterX="3237.15789473684" CenterY="840.8046387154327" Width="80.0" Height="20.0" ZOrder="34366" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="18103" />
  </DataNode>
  <DataNode TextLabel="Gucy2d" GraphId="f78fd" Type="GeneProduct" GroupRef="e83ec">
    <Comment Source="KeggConverter">Original kegg element: gene;243;mmu:14917 mmu:14918 mmu:14919 mmu:18160 mmu:230103 mmu:234889 mmu:239134 mmu:245650 mmu:54195 mmu:60596</Comment>
    <Graphics CenterX="263.6371674701754" CenterY="735.4877239289054" Width="80.0" Height="20.0" ZOrder="34367" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="14918" />
  </DataNode>
  <DataNode TextLabel="Itpa" GraphId="dc624" Type="GeneProduct">
    <Comment Source="KeggConverter">Original kegg element: gene;259;mmu:16434</Comment>
    <Graphics CenterX="1740.0" CenterY="456.0677966101696" Width="80.0" Height="20.0" ZOrder="34368" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="16434" />
  </DataNode>
  <DataNode TextLabel="Adcy1" GraphId="e0583" Type="GeneProduct" GroupRef="ae4c5">
    <Comment Source="KeggConverter">Original kegg element: gene;297;mmu:104110 mmu:104111 mmu:11512 mmu:11513 mmu:11514 mmu:11515 mmu:210044 mmu:224129 mmu:271639 mmu:432530</Comment>
    <Graphics CenterX="369.7182662538706" CenterY="653.7456805784038" Width="80.0" Height="20.0" ZOrder="34369" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="432530" />
  </DataNode>
  <DataNode TextLabel="Urea cycle and metabolism &#xA;of amino groups" GraphId="e13e6" Type="Pathway">
    <Comment Source="KeggConverter">Original kegg element: map;254;path:map00220</Comment>
    <Graphics CenterX="2182.508474576269" CenterY="622.4727649113729" Width="137.40458015267157" Height="27.816793893129564" ZOrder="34370" FontWeight="Bold" FontSize="10" Valign="Middle" Color="14961e" />
    <Xref Database="WikiPathways" ID="WP426" />
  </DataNode>
  <DataNode TextLabel="dGDP" GraphId="fa37c" Type="Metabolite">
    <Graphics CenterX="999.9999999999999" CenterY="946.0677966101696" Width="80.0" Height="31.951427103969802" ZOrder="34371" FontSize="10" Valign="Middle" Color="0000ff" />
    <Xref Database="KEGG Compound" ID="C00361" />
  </DataNode>
  <DataNode TextLabel="Pole3" GraphId="e2a91" Type="GeneProduct" GroupRef="fc208">
    <Comment Source="KeggConverter">Original kegg element: gene;244;mmu:18968 mmu:18969 mmu:18971 mmu:18972 mmu:18973 mmu:18974 mmu:19075 mmu:19076 mmu:59001 mmu:66979 mmu:67967 mmu:69745</Comment>
    <Graphics CenterX="641.1601255886964" CenterY="1075.9422079131537" Width="80.0" Height="20.0" ZOrder="34372" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="59001" />
  </DataNode>
  <DataNode TextLabel="Pklr" GraphId="f7119" Type="GeneProduct" GroupRef="ba7e8">
    <Comment Source="KeggConverter">Original kegg element: gene;299;mmu:18746 mmu:18770</Comment>
    <Graphics CenterX="932.788422339992" CenterY="1027.0323298347907" Width="80.0" Height="20.0" ZOrder="34373" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="18770" />
  </DataNode>
  <DataNode TextLabel="Polr3c" GraphId="b0a60" Type="GeneProduct" GroupRef="c746a">
    <Comment Source="KeggConverter">Original kegg element: gene;241;mmu:100043714 mmu:100046796 mmu:20016 mmu:20017 mmu:20018 mmu:20019 mmu:20020 mmu:20021 mmu:20022 mmu:218832 mmu:231329 mmu:245841 mmu:26939 mmu:625405 mmu:64424 mmu:66136 mmu:66420 mmu:66491 mmu:67005 mmu:67065 mmu:67486 mmu:67710 mmu:69241 mmu:69833 mmu:69870 mmu:69920 mmu:70408 mmu:70428 mmu:74414 mmu:78929</Comment>
    <Graphics CenterX="204.2166917255112" CenterY="1291.2983504696085" Width="92.46225755421057" Height="25.554043353358804" ZOrder="34374" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="74414" />
  </DataNode>
  <DataNode TextLabel="Ak4" GraphId="f21f3" Type="GeneProduct" GroupRef="b11a0">
    <Comment Source="KeggConverter">Original kegg element: gene;178;mmu:11636 mmu:11637 mmu:11639 mmu:229949 mmu:78801</Comment>
    <Graphics CenterX="2514.2679558011055" CenterY="702.212402846709" Width="80.0000000000001" Height="20.000000000000025" ZOrder="34375" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="11639" />
  </DataNode>
  <DataNode TextLabel="Nt5m" GraphId="a4e51" Type="GeneProduct" GroupRef="a692d">
    <Comment Source="KeggConverter">Original kegg element: gene;210;mmu:103850 mmu:107569 mmu:230718 mmu:23959 mmu:50773 mmu:70881 mmu:76952</Comment>
    <Graphics CenterX="1229.3511450381689" CenterY="899.3349721826878" Width="80.0" Height="20.0" ZOrder="34376" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="103850" />
  </DataNode>
  <DataNode TextLabel="DNA" GraphId="ca46a" Type="Metabolite">
    <Graphics CenterX="514.0" CenterY="946.0677966101696" Width="80.0" Height="20.0" ZOrder="34377" FontSize="10" Valign="Middle" Color="0000ff" />
    <Xref Database="KEGG Compound" ID="C00039" />
  </DataNode>
  <DataNode TextLabel="Nme6" GraphId="f71e7" Type="GeneProduct" GroupRef="e70b2">
    <Comment Source="KeggConverter">Original kegg element: gene;293;mmu:171567 mmu:18102 mmu:18103 mmu:54369 mmu:56520 mmu:75533 mmu:79059</Comment>
    <Graphics CenterX="931.9514884233737" CenterY="410.2728682749989" Width="80.0" Height="20.0" ZOrder="34378" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="54369" />
  </DataNode>
  <DataNode TextLabel="Papss1" GraphId="d3be5" Type="GeneProduct" GroupRef="e7810">
    <Comment Source="KeggConverter">Original kegg element: gene;249;mmu:23971 mmu:23972</Comment>
    <Graphics CenterX="3111.2304299889747" CenterY="143.5573225197616" Width="80.0" Height="20.0" ZOrder="34379" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="23971" />
  </DataNode>
  <DataNode TextLabel="Gm15210" GraphId="d61a5" Type="GeneProduct" GroupRef="ca3c6">
    <Comment Source="KeggConverter">Original kegg element: gene;201;mmu:100042069 mmu:23917 mmu:23918</Comment>
    <Graphics CenterX="1844.3030303030296" CenterY="854.1890087313819" Width="80.0" Height="20.0" ZOrder="34380" FontSize="10" Valign="Middle" />
    <Xref Database="Ensembl" ID="ENSMUSG00000062867" />
  </DataNode>
  <DataNode TextLabel="2'-Deoxyinosine 5'-phosphate" GraphId="e54f9" Type="Metabolite">
    <Graphics CenterX="1206.0871003307602" CenterY="474.0655915385048" Width="156.88864388092634" Height="20.0" ZOrder="34381" FontSize="10" Valign="Middle" Color="0000ff" />
    <Xref Database="KEGG Compound" ID="C06196" />
  </DataNode>
  <DataNode TextLabel="Deoxyguanosine" GraphId="f3b79" Type="Metabolite">
    <Graphics CenterX="737.2710997442451" CenterY="1110.0677966101696" Width="79.99999999999997" Height="31.951427103969714" ZOrder="34382" FontSize="10" Valign="Middle" Color="0000ff" />
    <Xref Database="KEGG Compound" ID="C00330" />
  </DataNode>
  <DataNode TextLabel="Prim1" GraphId="fc91d" Type="GeneProduct" GroupRef="d5f1e">
    <Comment Source="KeggConverter">Original kegg element: gene;170;mmu:18968 mmu:18969 mmu:18971 mmu:18972 mmu:18973 mmu:18974 mmu:19075 mmu:19076 mmu:59001 mmu:66979 mmu:67967 mmu:69745</Comment>
    <Graphics CenterX="3368.304299889746" CenterY="1069.2938164558143" Width="80.0" Height="20.0" ZOrder="34383" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="19075" />
  </DataNode>
  <DataNode TextLabel="Dck" GraphId="fe2b7" Type="GeneProduct">
    <Comment Source="KeggConverter">Original kegg element: gene;309;mmu:13178</Comment>
    <Graphics CenterX="2226.44155844156" CenterY="855.5829481253211" Width="80.0" Height="20.0" ZOrder="34384" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="13178" />
  </DataNode>
  <DataNode TextLabel="Pole4" GraphId="ef508" Type="GeneProduct" GroupRef="fc208">
    <Comment Source="KeggConverter">Original kegg element: gene;244;mmu:18968 mmu:18969 mmu:18971 mmu:18972 mmu:18973 mmu:18974 mmu:19075 mmu:19076 mmu:59001 mmu:66979 mmu:67967 mmu:69745</Comment>
    <Graphics CenterX="561.0973312401883" CenterY="1015.2514700795577" Width="80.0" Height="20.0" ZOrder="34385" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="66979" />
  </DataNode>
  <DataNode TextLabel="Pde4b" GraphId="e3c76" Type="GeneProduct" GroupRef="f5806">
    <Comment Source="KeggConverter">Original kegg element: gene;165;mmu:110385 mmu:18573 mmu:18574 mmu:18575 mmu:18576 mmu:18577 mmu:18578 mmu:18583 mmu:18584 mmu:207728 mmu:218461 mmu:238871 mmu:23984 mmu:241489 mmu:29863 mmu:54611</Comment>
    <Graphics CenterX="2713.2557883131203" CenterY="248.09536000597984" Width="80.0" Height="20.0" ZOrder="34386" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="18578" />
  </DataNode>
  <DataNode TextLabel="Entpd6" GraphId="a238f" Type="GeneProduct" GroupRef="fc1ac">
    <Comment Source="KeggConverter">Original kegg element: gene;303;mmu:12497 mmu:12499 mmu:67464 mmu:76025</Comment>
    <Graphics CenterX="1882.5454545454545" CenterY="669.1587057010789" Width="80.0" Height="20.0" ZOrder="34387" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="12497" />
  </DataNode>
  <DataNode TextLabel="Rrm1" GraphId="c1d83" Type="GeneProduct" GroupRef="e1c60">
    <Comment Source="KeggConverter">Original kegg element: gene;133;mmu:20133 mmu:20135 mmu:382985</Comment>
    <Graphics CenterX="1074.9515616523279" CenterY="881.5401673766575" Width="80.0" Height="20.0" ZOrder="34388" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="20133" />
  </DataNode>
  <DataNode TextLabel="Pde4c" GraphId="fc20b" Type="GeneProduct" GroupRef="e4165">
    <Comment Source="KeggConverter">Original kegg element: gene;245;mmu:110385 mmu:110855 mmu:18573 mmu:18574 mmu:18575 mmu:18576 mmu:18577 mmu:18578 mmu:18582 mmu:18583 mmu:18584 mmu:18585 mmu:18587 mmu:18588 mmu:207728 mmu:218461 mmu:225600 mmu:238871 mmu:23984 mmu:241489 mmu:242202 mmu:29863 mmu:54611 mmu:78600</Comment>
    <Graphics CenterX="141.79898241873565" CenterY="763.8574623569884" Width="80.0" Height="20.0" ZOrder="34389" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="110385" />
  </DataNode>
  <DataNode TextLabel="Entpd1" GraphId="f315f" Type="GeneProduct" GroupRef="c6c79">
    <Comment Source="KeggConverter">Original kegg element: gene;197;mmu:12495 mmu:215446 mmu:72090</Comment>
    <Graphics CenterX="1937.956709956711" CenterY="521.5483160906884" Width="80.0" Height="20.0" ZOrder="34390" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="12495" />
  </DataNode>
  <DataNode TextLabel="3',5'-Cyclic AMP" GraphId="d4081" Type="Metabolite">
    <Graphics CenterX="3594.4859511820955" CenterY="504.15937711238496" Width="96.0" Height="20.0" ZOrder="34392" FontSize="10" Valign="Middle" Color="0000ff" />
    <Xref Database="KEGG Compound" ID="C00575" />
  </DataNode>
  <DataNode TextLabel="D-Ribose 5-phosphate" GraphId="ea292" Type="Metabolite">
    <Graphics CenterX="318.2686567164179" CenterY="234.35933266032634" Width="111.46268656716411" Height="20.0" ZOrder="34393" FontSize="10" Valign="Middle" Color="0000ff" />
    <Xref Database="KEGG Compound" ID="C00117" />
  </DataNode>
  <DataNode TextLabel="Entpd3" GraphId="a4586" Type="GeneProduct" GroupRef="e2820">
    <Comment Source="KeggConverter">Original kegg element: gene;177;mmu:12495 mmu:215446 mmu:72090</Comment>
    <Graphics CenterX="2613.9496230029104" CenterY="828.5375759478502" Width="80.0" Height="20.0" ZOrder="34394" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="215446" />
  </DataNode>
  <DataNode TextLabel="Entpd1" GraphId="d6169" Type="GeneProduct" GroupRef="c0020">
    <Comment Source="KeggConverter">Original kegg element: gene;204;mmu:12495 mmu:215446 mmu:72090</Comment>
    <Graphics CenterX="1051.6010230179043" CenterY="665.1163899605533" Width="80.0" Height="20.0" ZOrder="34395" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="12495" />
  </DataNode>
  <DataNode TextLabel="Polr1a" GraphId="d6581" Type="GeneProduct" GroupRef="afea2">
    <Comment Source="KeggConverter">Original kegg element: gene;168;mmu:100043714 mmu:100046796 mmu:20016 mmu:20017 mmu:20018 mmu:20019 mmu:20020 mmu:20021 mmu:20022 mmu:218832 mmu:231329 mmu:245841 mmu:26939 mmu:625405 mmu:64424 mmu:66136 mmu:66420 mmu:66491 mmu:67005 mmu:67065 mmu:67486 mmu:67710 mmu:69241 mmu:69833 mmu:69870 mmu:69920 mmu:70408 mmu:70428 mmu:74414 mmu:78929</Comment>
    <Graphics CenterX="3295.1671030542884" CenterY="551.9850218382113" Width="90.94297214511298" Height="23.592612772064896" ZOrder="34396" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="20019" />
  </DataNode>
  <DataNode TextLabel="Nme5" GraphId="f8d18" Type="GeneProduct" GroupRef="e70b2">
    <Comment Source="KeggConverter">Original kegg element: gene;293;mmu:171567 mmu:18102 mmu:18103 mmu:54369 mmu:56520 mmu:75533 mmu:79059</Comment>
    <Graphics CenterX="851.9514884233735" CenterY="410.2728682749989" Width="80.0" Height="20.0" ZOrder="34397" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="75533" />
  </DataNode>
  <DataNode TextLabel="Impdh2" GraphId="b6a48" Type="GeneProduct" GroupRef="ca3c6">
    <Comment Source="KeggConverter">Original kegg element: gene;201;mmu:100042069 mmu:23917 mmu:23918</Comment>
    <Graphics CenterX="1844.3030303030296" CenterY="874.1890087313819" Width="80.0" Height="20.0" ZOrder="34398" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="23918" />
  </DataNode>
  <DataNode TextLabel="Polr2e" GraphId="ecc3e" Type="GeneProduct" GroupRef="afea2">
    <Comment Source="KeggConverter">Original kegg element: gene;168;mmu:100043714 mmu:100046796 mmu:20016 mmu:20017 mmu:20018 mmu:20019 mmu:20020 mmu:20021 mmu:20022 mmu:218832 mmu:231329 mmu:245841 mmu:26939 mmu:625405 mmu:64424 mmu:66136 mmu:66420 mmu:66491 mmu:67005 mmu:67065 mmu:67486 mmu:67710 mmu:69241 mmu:69833 mmu:69870 mmu:69920 mmu:70408 mmu:70428 mmu:74414 mmu:78929</Comment>
    <Graphics CenterX="3386.1100751994018" CenterY="575.5776346102762" Width="90.94297214511298" Height="23.592612772064896" ZOrder="34399" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="66420" />
  </DataNode>
  <DataNode TextLabel="Pentose phosphate pathway" GraphId="c1e5e" Type="Pathway">
    <Comment Source="KeggConverter">Original kegg element: map;148;path:mmu00030</Comment>
    <Graphics CenterX="488.52037617554856" CenterY="89.06779661016958" Width="148.0" Height="20.0" ZOrder="34400" FontWeight="Bold" FontSize="10" Valign="Middle" Color="14961e" />
    <Xref Database="WikiPathways" ID="WP63" />
  </DataNode>
  <DataNode TextLabel="Pde4d" GraphId="abe2c" Type="GeneProduct" GroupRef="f5806">
    <Comment Source="KeggConverter">Original kegg element: gene;165;mmu:110385 mmu:18573 mmu:18574 mmu:18575 mmu:18576 mmu:18577 mmu:18578 mmu:18583 mmu:18584 mmu:207728 mmu:218461 mmu:238871 mmu:23984 mmu:241489 mmu:29863 mmu:54611</Comment>
    <Graphics CenterX="2633.2557883131203" CenterY="228.09536000597984" Width="80.0" Height="20.0" ZOrder="34401" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="238871" />
  </DataNode>
  <DataNode TextLabel="Nme4" GraphId="ad5d3" Type="GeneProduct" GroupRef="bfdae">
    <Comment Source="KeggConverter">Original kegg element: gene;174;mmu:171567 mmu:18102 mmu:18103 mmu:54369 mmu:56520 mmu:75533 mmu:79059</Comment>
    <Graphics CenterX="3237.1578947368394" CenterY="860.8046387154327" Width="80.0" Height="20.0" ZOrder="34402" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="56520" />
  </DataNode>
  <DataNode TextLabel="Adcy2" GraphId="be197" Type="GeneProduct" GroupRef="ae4c5">
    <Comment Source="KeggConverter">Original kegg element: gene;297;mmu:104110 mmu:104111 mmu:11512 mmu:11513 mmu:11514 mmu:11515 mmu:210044 mmu:224129 mmu:271639 mmu:432530</Comment>
    <Graphics CenterX="369.7182662538706" CenterY="813.7456805784034" Width="80.0" Height="20.0" ZOrder="34403" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="210044" />
  </DataNode>
  <DataNode TextLabel="Nme3" GraphId="d5ad5" Type="GeneProduct" GroupRef="bfdae">
    <Comment Source="KeggConverter">Original kegg element: gene;174;mmu:171567 mmu:18102 mmu:18103 mmu:54369 mmu:56520 mmu:75533 mmu:79059</Comment>
    <Graphics CenterX="3157.1578947368403" CenterY="860.8046387154327" Width="80.0" Height="20.0" ZOrder="34404" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="79059" />
  </DataNode>
  <DataNode TextLabel="Adcy10" GraphId="aff88" Type="GeneProduct" GroupRef="ae4c5">
    <Comment Source="KeggConverter">Original kegg element: gene;297;mmu:104110 mmu:104111 mmu:11512 mmu:11513 mmu:11514 mmu:11515 mmu:210044 mmu:224129 mmu:271639 mmu:432530</Comment>
    <Graphics CenterX="369.7182662538706" CenterY="833.7456805784035" Width="80.0" Height="20.0" ZOrder="34405" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="271639" />
  </DataNode>
  <DataNode TextLabel="Prps1l1" GraphId="cf4b2" Type="GeneProduct" GroupRef="ad65e">
    <Comment Source="KeggConverter">Original kegg element: gene;153;mmu:110639 mmu:19139 mmu:328099 mmu:75456</Comment>
    <Graphics CenterX="391.9686520376172" CenterY="141.03958344402525" Width="80.0" Height="20.0" ZOrder="34406" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="75456" />
  </DataNode>
  <DataNode TextLabel="Gucy2c" GraphId="d3b20" Type="GeneProduct" GroupRef="e83ec">
    <Comment Source="KeggConverter">Original kegg element: gene;243;mmu:14917 mmu:14918 mmu:14919 mmu:18160 mmu:230103 mmu:234889 mmu:239134 mmu:245650 mmu:54195 mmu:60596</Comment>
    <Graphics CenterX="263.6371674701754" CenterY="755.4877239289056" Width="80.0" Height="20.0" ZOrder="34407" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="14917" />
  </DataNode>
  <DataNode TextLabel="Pole3" GraphId="f7ac4" Type="GeneProduct" GroupRef="d5f1e">
    <Comment Source="KeggConverter">Original kegg element: gene;170;mmu:18968 mmu:18969 mmu:18971 mmu:18972 mmu:18973 mmu:18974 mmu:19075 mmu:19076 mmu:59001 mmu:66979 mmu:67967 mmu:69745</Comment>
    <Graphics CenterX="3368.304299889746" CenterY="1089.2938164558143" Width="80.0" Height="20.0" ZOrder="34408" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="59001" />
  </DataNode>
  <DataNode TextLabel="Nudt5" GraphId="f10c2" Type="GeneProduct" GroupRef="a021a">
    <Comment Source="KeggConverter">Original kegg element: gene;280;mmu:53893 mmu:66358 mmu:74167</Comment>
    <Graphics CenterX="218.10447761194033" CenterY="459.85884138628853" Width="80.0" Height="20.0" ZOrder="34409" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="53893" />
  </DataNode>
  <DataNode TextLabel="Polr3h" GraphId="a6151" Type="GeneProduct" GroupRef="c746a">
    <Comment Source="KeggConverter">Original kegg element: gene;241;mmu:100043714 mmu:100046796 mmu:20016 mmu:20017 mmu:20018 mmu:20019 mmu:20020 mmu:20021 mmu:20022 mmu:218832 mmu:231329 mmu:245841 mmu:26939 mmu:625405 mmu:64424 mmu:66136 mmu:66420 mmu:66491 mmu:67005 mmu:67065 mmu:67486 mmu:67710 mmu:69241 mmu:69833 mmu:69870 mmu:69920 mmu:70408 mmu:70428 mmu:74414 mmu:78929</Comment>
    <Graphics CenterX="19.048068185003256" CenterY="1061.8430060509202" Width="92.46225755421057" Height="25.554043353358804" ZOrder="34410" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="78929" />
  </DataNode>
  <DataNode TextLabel="Nt5c" GraphId="e2008" Type="GeneProduct" GroupRef="bad2e">
    <Comment Source="KeggConverter">Original kegg element: gene;182;mmu:103850 mmu:107569 mmu:230718 mmu:23959 mmu:50773 mmu:70881 mmu:76952</Comment>
    <Graphics CenterX="2495.9226519337017" CenterY="942.8598558668045" Width="80.0" Height="20.0" ZOrder="34411" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="50773" />
  </DataNode>
  <DataNode TextLabel="Urad" GraphId="a5ded" Type="GeneProduct">
    <Comment Source="KeggConverter">Original kegg element: gene;429;mmu:231903</Comment>
    <Graphics CenterX="1919.7922077922076" CenterY="1436.777753320126" Width="80.0" Height="20.0" ZOrder="34412" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="231903" />
  </DataNode>
  <DataNode TextLabel="Prps2" GraphId="d5694" Type="GeneProduct" GroupRef="ad65e">
    <Comment Source="KeggConverter">Original kegg element: gene;153;mmu:110639 mmu:19139 mmu:328099 mmu:75456</Comment>
    <Graphics CenterX="391.9686520376172" CenterY="181.03958344402525" Width="80.0" Height="20.0" ZOrder="34413" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="110639" />
  </DataNode>
  <DataNode TextLabel="Polr2l" GraphId="e8299" Type="GeneProduct" GroupRef="afea2">
    <Comment Source="KeggConverter">Original kegg element: gene;168;mmu:100043714 mmu:100046796 mmu:20016 mmu:20017 mmu:20018 mmu:20019 mmu:20020 mmu:20021 mmu:20022 mmu:218832 mmu:231329 mmu:245841 mmu:26939 mmu:625405 mmu:64424 mmu:66136 mmu:66420 mmu:66491 mmu:67005 mmu:67065 mmu:67486 mmu:67710 mmu:69241 mmu:69833 mmu:69870 mmu:69920 mmu:70408 mmu:70428 mmu:74414 mmu:78929</Comment>
    <Graphics CenterX="3204.224130909176" CenterY="646.3554729264708" Width="90.94297214511298" Height="23.592612772064896" ZOrder="34415" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="66491" />
  </DataNode>
  <DataNode TextLabel="Nt5c" GraphId="b961a" Type="GeneProduct" GroupRef="b3409">
    <Comment Source="KeggConverter">Original kegg element: gene;239;mmu:103850 mmu:107569 mmu:230718 mmu:23959 mmu:50773 mmu:70881 mmu:76952</Comment>
    <Graphics CenterX="961.8095238095249" CenterY="1196.3881429305188" Width="80.0" Height="20.0" ZOrder="34416" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="50773" />
  </DataNode>
  <DataNode TextLabel="Polr1b" GraphId="c4b69" Type="GeneProduct" GroupRef="c746a">
    <Comment Source="KeggConverter">Original kegg element: gene;241;mmu:100043714 mmu:100046796 mmu:20016 mmu:20017 mmu:20018 mmu:20019 mmu:20020 mmu:20021 mmu:20022 mmu:218832 mmu:231329 mmu:245841 mmu:26939 mmu:625405 mmu:64424 mmu:66136 mmu:66420 mmu:66491 mmu:67005 mmu:67065 mmu:67486 mmu:67710 mmu:69241 mmu:69833 mmu:69870 mmu:69920 mmu:70408 mmu:70428 mmu:74414 mmu:78929</Comment>
    <Graphics CenterX="110.76377692730505" CenterY="1138.721474504911" Width="92.46225755421065" Height="25.554043353358804" ZOrder="34417" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="20017" />
  </DataNode>
  <DataNode TextLabel="Polr2i" GraphId="d0ae0" Type="GeneProduct" GroupRef="c746a">
    <Comment Source="KeggConverter">Original kegg element: gene;241;mmu:100043714 mmu:100046796 mmu:20016 mmu:20017 mmu:20018 mmu:20019 mmu:20020 mmu:20021 mmu:20022 mmu:218832 mmu:231329 mmu:245841 mmu:26939 mmu:625405 mmu:64424 mmu:66136 mmu:66420 mmu:66491 mmu:67005 mmu:67065 mmu:67486 mmu:67710 mmu:69241 mmu:69833 mmu:69870 mmu:69920 mmu:70408 mmu:70428 mmu:74414 mmu:78929</Comment>
    <Graphics CenterX="19.048068185003256" CenterY="1112.9510927576378" Width="92.46225755421057" Height="25.554043353358804" ZOrder="34418" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="69920" />
  </DataNode>
  <DataNode TextLabel="Nme1" GraphId="aee07" Type="GeneProduct" GroupRef="cf79b">
    <Comment Source="KeggConverter">Original kegg element: gene;175;mmu:171567 mmu:18102 mmu:18103 mmu:54369 mmu:56520 mmu:75533 mmu:79059</Comment>
    <Graphics CenterX="2941.409040793826" CenterY="992.2706632033339" Width="80.0" Height="20.0" ZOrder="34419" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="18102" />
  </DataNode>
  <DataNode TextLabel="Allantoate" GraphId="b798a" Type="Metabolite">
    <Graphics CenterX="2196.0" CenterY="1478.0677966101696" Width="80.0" Height="20.0" ZOrder="34420" FontSize="10" Valign="Middle" Color="0000ff" />
    <Xref Database="KEGG Compound" ID="C00499" />
  </DataNode>
  <DataNode TextLabel="Pnp2" GraphId="a15a6" Type="GeneProduct" GroupRef="d3d8f">
    <Comment Source="KeggConverter">Original kegg element: gene;240;mmu:18950 mmu:667034</Comment>
    <Graphics CenterX="1424.3117544033569" CenterY="1097.7096458550766" Width="80.0" Height="20.0" ZOrder="34421" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="667034" />
  </DataNode>
  <DataNode TextLabel="Nt5c2" GraphId="d0e6c" Type="GeneProduct" GroupRef="bad2e">
    <Comment Source="KeggConverter">Original kegg element: gene;182;mmu:103850 mmu:107569 mmu:230718 mmu:23959 mmu:50773 mmu:70881 mmu:76952</Comment>
    <Graphics CenterX="2495.9226519337017" CenterY="962.8598558668064" Width="80.0" Height="20.0" ZOrder="34422" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="76952" />
  </DataNode>
  <DataNode TextLabel="Xanthine" GraphId="bb144" Type="Metabolite">
    <Graphics CenterX="1668.0" CenterY="1192.0920830581847" Width="80.00000000000007" Height="31.951427103969714" ZOrder="34423" FontSize="10" Valign="Middle" Color="0000ff" />
    <Xref Database="KEGG Compound" ID="C00385" />
  </DataNode>
  <DataNode TextLabel="Urea" GraphId="c331f" Type="Metabolite">
    <Graphics CenterX="2408.987012987013" CenterY="1537.1067576491303" Width="80.0" Height="20.0" ZOrder="34424" FontSize="10" Valign="Middle" Color="0000ff" />
    <Xref Database="KEGG Compound" ID="C00086" />
  </DataNode>
  <DataNode TextLabel="3',5'-Cyclic GMP" GraphId="cd9e7" Type="Metabolite">
    <Graphics CenterX="348.0" CenterY="596.0677966101696" Width="80.0" Height="20.0" ZOrder="34426" FontSize="10" Valign="Middle" Color="0000ff" />
    <Xref Database="KEGG Compound" ID="C00942" />
  </DataNode>
  <DataNode TextLabel="Nt5m" GraphId="a372d" Type="GeneProduct" GroupRef="b3409">
    <Comment Source="KeggConverter">Original kegg element: gene;239;mmu:103850 mmu:107569 mmu:230718 mmu:23959 mmu:50773 mmu:70881 mmu:76952</Comment>
    <Graphics CenterX="881.8095238095249" CenterY="1196.3881429305188" Width="80.0" Height="20.0" ZOrder="34427" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="103850" />
  </DataNode>
  <DataNode TextLabel="Polr3k" GraphId="a2f4e" Type="GeneProduct" GroupRef="c746a">
    <Comment Source="KeggConverter">Original kegg element: gene;241;mmu:100043714 mmu:100046796 mmu:20016 mmu:20017 mmu:20018 mmu:20019 mmu:20020 mmu:20021 mmu:20022 mmu:218832 mmu:231329 mmu:245841 mmu:26939 mmu:625405 mmu:64424 mmu:66136 mmu:66420 mmu:66491 mmu:67005 mmu:67065 mmu:67486 mmu:67710 mmu:69241 mmu:69833 mmu:69870 mmu:69920 mmu:70408 mmu:70428 mmu:74414 mmu:78929</Comment>
    <Graphics CenterX="204.21669172551108" CenterY="1163.528133702814" Width="92.46225755421057" Height="25.554043353358804" ZOrder="34428" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="67005" />
  </DataNode>
  <DataNode TextLabel="ATP" GraphId="f931d" Type="Metabolite">
    <Graphics CenterX="2359.8453038674043" CenterY="607.2224927427666" Width="80.0" Height="20.0" ZOrder="34429" FontSize="10" Valign="Middle" Color="0000ff" />
    <Xref Database="KEGG Compound" ID="C00002" />
  </DataNode>
  <DataNode TextLabel="Ak5" GraphId="d9a6b" Type="GeneProduct" GroupRef="d54ef">
    <Comment Source="KeggConverter">Original kegg element: gene;285;mmu:11636 mmu:11637 mmu:11639 mmu:229949 mmu:78801</Comment>
    <Graphics CenterX="2601.0373715597634" CenterY="995.7173004204114" Width="80.0" Height="20.0" ZOrder="34430" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="229949" />
  </DataNode>
  <DataNode TextLabel="Aminoimidazole &#xA;ribotide" GraphId="b06a9" Type="Metabolite">
    <Graphics CenterX="1408.5789473684213" CenterY="234.35933266032634" Width="85.6050156739812" Height="26.63322884012541" ZOrder="34431" FontSize="10" Valign="Middle" Color="0000ff" />
    <Xref Database="KEGG Compound" ID="C03373" />
  </DataNode>
  <DataNode TextLabel="Cant1" GraphId="f43d8" Type="GeneProduct" GroupRef="fc1ac">
    <Comment Source="KeggConverter">Original kegg element: gene;303;mmu:12497 mmu:12499 mmu:67464 mmu:76025</Comment>
    <Graphics CenterX="1882.5454545454545" CenterY="629.1587057010789" Width="80.0" Height="20.0" ZOrder="34432" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="76025" />
  </DataNode>
  <DataNode TextLabel="Polr3gl" GraphId="c7454" Type="GeneProduct" GroupRef="afea2">
    <Comment Source="KeggConverter">Original kegg element: gene;168;mmu:100043714 mmu:100046796 mmu:20016 mmu:20017 mmu:20018 mmu:20019 mmu:20020 mmu:20021 mmu:20022 mmu:218832 mmu:231329 mmu:245841 mmu:26939 mmu:625405 mmu:64424 mmu:66136 mmu:66420 mmu:66491 mmu:67005 mmu:67065 mmu:67486 mmu:67710 mmu:69241 mmu:69833 mmu:69870 mmu:69920 mmu:70408 mmu:70428 mmu:74414 mmu:78929</Comment>
    <Graphics CenterX="3386.1100751994018" CenterY="669.9480856985358" Width="90.94297214511298" Height="23.592612772064896" ZOrder="34433" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="69870" />
  </DataNode>
  <DataNode TextLabel="Nt5c2" GraphId="ac9ce" Type="GeneProduct" GroupRef="a692d">
    <Comment Source="KeggConverter">Original kegg element: gene;210;mmu:103850 mmu:107569 mmu:230718 mmu:23959 mmu:50773 mmu:70881 mmu:76952</Comment>
    <Graphics CenterX="1229.3511450381689" CenterY="959.3349721826887" Width="80.0" Height="20.0" ZOrder="34434" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="76952" />
  </DataNode>
  <DataNode TextLabel="Nt5e" GraphId="decca" Type="GeneProduct" GroupRef="e7a69">
    <Comment Source="KeggConverter">Original kegg element: gene;215;mmu:103850 mmu:107569 mmu:230718 mmu:23959 mmu:50773 mmu:70881 mmu:76952</Comment>
    <Graphics CenterX="1845.196392785571" CenterY="936.0136883937391" Width="80.0" Height="20.0" ZOrder="34436" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="23959" />
  </DataNode>
  <DataNode TextLabel="Entpd6" GraphId="c8db5" Type="GeneProduct" GroupRef="add34">
    <Comment Source="KeggConverter">Original kegg element: gene;205;mmu:12497 mmu:12499 mmu:67464 mmu:76025</Comment>
    <Graphics CenterX="1252.3682864450127" CenterY="673.868308119121" Width="80.0" Height="20.0" ZOrder="34438" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="12497" />
  </DataNode>
  <DataNode TextLabel="Nme3" GraphId="aafd5" Type="GeneProduct" GroupRef="cf79b">
    <Comment Source="KeggConverter">Original kegg element: gene;175;mmu:171567 mmu:18102 mmu:18103 mmu:54369 mmu:56520 mmu:75533 mmu:79059</Comment>
    <Graphics CenterX="2941.409040793826" CenterY="1012.2706632033339" Width="80.0" Height="20.0" ZOrder="34439" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="79059" />
  </DataNode>
  <DataNode TextLabel="Polr3b" GraphId="e6417" Type="GeneProduct" GroupRef="c746a">
    <Comment Source="KeggConverter">Original kegg element: gene;241;mmu:100043714 mmu:100046796 mmu:20016 mmu:20017 mmu:20018 mmu:20019 mmu:20020 mmu:20021 mmu:20022 mmu:218832 mmu:231329 mmu:245841 mmu:26939 mmu:625405 mmu:64424 mmu:66136 mmu:66420 mmu:66491 mmu:67005 mmu:67065 mmu:67486 mmu:67710 mmu:69241 mmu:69833 mmu:69870 mmu:69920 mmu:70408 mmu:70428 mmu:74414 mmu:78929</Comment>
    <Graphics CenterX="19.048068185003256" CenterY="1087.397049404279" Width="92.46225755421057" Height="25.554043353358804" ZOrder="34441" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="70428" />
  </DataNode>
  <DataNode TextLabel="Nme5" GraphId="bb0cd" Type="GeneProduct" GroupRef="bfdae">
    <Comment Source="KeggConverter">Original kegg element: gene;174;mmu:171567 mmu:18102 mmu:18103 mmu:54369 mmu:56520 mmu:75533 mmu:79059</Comment>
    <Graphics CenterX="3157.15789473684" CenterY="880.8046387154327" Width="80.0" Height="20.0" ZOrder="34442" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="75533" />
  </DataNode>
  <DataNode TextLabel="Prim2" GraphId="d027b" Type="GeneProduct" GroupRef="d5f1e">
    <Comment Source="KeggConverter">Original kegg element: gene;170;mmu:18968 mmu:18969 mmu:18971 mmu:18972 mmu:18973 mmu:18974 mmu:19075 mmu:19076 mmu:59001 mmu:66979 mmu:67967 mmu:69745</Comment>
    <Graphics CenterX="3288.304299889746" CenterY="1049.2938164558145" Width="80.0" Height="20.0" ZOrder="34444" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="19076" />
  </DataNode>
  <DataNode TextLabel="inosine" GraphId="cc220" Type="Metabolite">
    <Graphics CenterX="2037.2368421052636" CenterY="990.0677966101696" Width="44.47368421052715" Height="20.0" ZOrder="34445" FontSize="10" Valign="Middle" Color="0000ff" />
    <Xref Database="KEGG Compound" ID="C00294" />
  </DataNode>
  <DataNode TextLabel="Nme5" GraphId="d35d1" Type="GeneProduct" GroupRef="d2b7a">
    <Comment Source="KeggConverter">Original kegg element: gene;198;mmu:171567 mmu:18102 mmu:18103 mmu:54369 mmu:56520 mmu:75533 mmu:79059</Comment>
    <Graphics CenterX="1477.7289603052322" CenterY="496.5266710690438" Width="80.0" Height="20.0" ZOrder="34447" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="75533" />
  </DataNode>
  <DataNode TextLabel="Entpd1" GraphId="a39c0" Type="GeneProduct" GroupRef="bd17f">
    <Comment Source="KeggConverter">Original kegg element: gene;199;mmu:12495 mmu:215446 mmu:72090</Comment>
    <Graphics CenterX="1630.1744808863455" CenterY="667.5180864333413" Width="80.0" Height="20.0" ZOrder="34448" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="12495" />
  </DataNode>
  <DataNode TextLabel="Pole2" GraphId="f77db" Type="GeneProduct" GroupRef="d5f1e">
    <Comment Source="KeggConverter">Original kegg element: gene;170;mmu:18968 mmu:18969 mmu:18971 mmu:18972 mmu:18973 mmu:18974 mmu:19075 mmu:19076 mmu:59001 mmu:66979 mmu:67967 mmu:69745</Comment>
    <Graphics CenterX="3288.304299889746" CenterY="1069.2938164558145" Width="80.0" Height="20.0" ZOrder="34449" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="18974" />
  </DataNode>
  <DataNode TextLabel="Pde7b" GraphId="dea74" Type="GeneProduct" GroupRef="e4165">
    <Comment Source="KeggConverter">Original kegg element: gene;245;mmu:110385 mmu:110855 mmu:18573 mmu:18574 mmu:18575 mmu:18576 mmu:18577 mmu:18578 mmu:18582 mmu:18583 mmu:18584 mmu:18585 mmu:18587 mmu:18588 mmu:207728 mmu:218461 mmu:225600 mmu:238871 mmu:23984 mmu:241489 mmu:242202 mmu:29863 mmu:54611 mmu:78600</Comment>
    <Graphics CenterX="141.79898241873565" CenterY="543.8574623569884" Width="80.0" Height="20.0" ZOrder="34450" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="29863" />
  </DataNode>
  <DataNode TextLabel="Adk" GraphId="aa7a5" Type="GeneProduct">
    <Comment Source="KeggConverter">Original kegg element: gene;183;mmu:11534</Comment>
    <Graphics CenterX="2234.583225934373" CenterY="901.1192820204342" Width="80.0" Height="20.0" ZOrder="34451" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="11534" />
  </DataNode>
  <DataNode TextLabel="Adcy5" GraphId="edd25" Type="GeneProduct" GroupRef="ae4c5">
    <Comment Source="KeggConverter">Original kegg element: gene;297;mmu:104110 mmu:104111 mmu:11512 mmu:11513 mmu:11514 mmu:11515 mmu:210044 mmu:224129 mmu:271639 mmu:432530</Comment>
    <Graphics CenterX="369.7182662538706" CenterY="673.7456805784033" Width="80.0" Height="20.0" ZOrder="34452" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="224129" />
  </DataNode>
  <DataNode TextLabel="Pgm2" GraphId="db168" Type="GeneProduct" GroupRef="ba84c">
    <Comment Source="KeggConverter">Original kegg element: gene;431;mmu:66681 mmu:72157</Comment>
    <Graphics CenterX="223.02985074626872" CenterY="176.396154819125" Width="80.0" Height="20.0" ZOrder="34453" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="72157" />
  </DataNode>
  <DataNode TextLabel="Pkm2" GraphId="c4e20" Type="GeneProduct" GroupRef="ba7e8">
    <Comment Source="KeggConverter">Original kegg element: gene;299;mmu:18746 mmu:18770</Comment>
    <Graphics CenterX="932.788422339992" CenterY="1047.0323298347907" Width="80.0" Height="20.0" ZOrder="34454" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="18746" />
  </DataNode>
  <DataNode TextLabel="Polr3gl" GraphId="a5d01" Type="GeneProduct" GroupRef="c746a">
    <Comment Source="KeggConverter">Original kegg element: gene;241;mmu:100043714 mmu:100046796 mmu:20016 mmu:20017 mmu:20018 mmu:20019 mmu:20020 mmu:20021 mmu:20022 mmu:218832 mmu:231329 mmu:245841 mmu:26939 mmu:625405 mmu:64424 mmu:66136 mmu:66420 mmu:66491 mmu:67005 mmu:67065 mmu:67486 mmu:67710 mmu:69241 mmu:69833 mmu:69870 mmu:69920 mmu:70408 mmu:70428 mmu:74414 mmu:78929</Comment>
    <Graphics CenterX="204.2166917255112" CenterY="1240.1902637628907" Width="92.46225755421057" Height="25.554043353358804" ZOrder="34455" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="69870" />
  </DataNode>
  <DataNode TextLabel="Entpd4" GraphId="c0c4e" Type="GeneProduct" GroupRef="add34">
    <Comment Source="KeggConverter">Original kegg element: gene;205;mmu:12497 mmu:12499 mmu:67464 mmu:76025</Comment>
    <Graphics CenterX="1252.3682864450127" CenterY="693.868308119121" Width="80.0" Height="20.0" ZOrder="34456" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="67464" />
  </DataNode>
  <DataNode TextLabel="DNA" GraphId="ba4bb" Type="Metabolite">
    <Graphics CenterX="3460.1234840132315" CenterY="944.0677966101696" Width="79.99999999999994" Height="25.660874519299295" ZOrder="34457" FontSize="10" Valign="Middle" Color="0000ff" />
    <Xref Database="KEGG Compound" ID="C00039" />
  </DataNode>
  <DataNode TextLabel="Nt5c3" GraphId="fdda9" Type="GeneProduct" GroupRef="b3409">
    <Comment Source="KeggConverter">Original kegg element: gene;239;mmu:103850 mmu:107569 mmu:230718 mmu:23959 mmu:50773 mmu:70881 mmu:76952</Comment>
    <Graphics CenterX="881.8095238095249" CenterY="1176.3881429305188" Width="80.0" Height="20.0" ZOrder="34458" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="107569" />
  </DataNode>
  <DataNode TextLabel="Pkm2" GraphId="aef89" Type="GeneProduct" GroupRef="cb381">
    <Comment Source="KeggConverter">Original kegg element: gene;298;mmu:18746 mmu:18770</Comment>
    <Graphics CenterX="843.1764705882362" CenterY="757.055008886383" Width="80.0" Height="20.0" ZOrder="34459" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="18746" />
  </DataNode>
  <DataNode TextLabel="Polr2f" GraphId="c8701" Type="GeneProduct" GroupRef="c746a">
    <Comment Source="KeggConverter">Original kegg element: gene;241;mmu:100043714 mmu:100046796 mmu:20016 mmu:20017 mmu:20018 mmu:20019 mmu:20020 mmu:20021 mmu:20022 mmu:218832 mmu:231329 mmu:245841 mmu:26939 mmu:625405 mmu:64424 mmu:66136 mmu:66420 mmu:66491 mmu:67005 mmu:67065 mmu:67486 mmu:67710 mmu:69241 mmu:69833 mmu:69870 mmu:69920 mmu:70408 mmu:70428 mmu:74414 mmu:78929</Comment>
    <Graphics CenterX="19.048068185003256" CenterY="1138.5051361109965" Width="92.46225755421057" Height="25.554043353358804" ZOrder="34460" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="69833" />
  </DataNode>
  <DataNode TextLabel="Polr3a" GraphId="b1123" Type="GeneProduct" GroupRef="c746a">
    <Comment Source="KeggConverter">Original kegg element: gene;241;mmu:100043714 mmu:100046796 mmu:20016 mmu:20017 mmu:20018 mmu:20019 mmu:20020 mmu:20021 mmu:20022 mmu:218832 mmu:231329 mmu:245841 mmu:26939 mmu:625405 mmu:64424 mmu:66136 mmu:66420 mmu:66491 mmu:67005 mmu:67065 mmu:67486 mmu:67710 mmu:69241 mmu:69833 mmu:69870 mmu:69920 mmu:70408 mmu:70428 mmu:74414 mmu:78929</Comment>
    <Graphics CenterX="110.76377692730505" CenterY="1062.0593444448348" Width="92.46225755421065" Height="25.554043353358804" ZOrder="34461" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="218832" />
  </DataNode>
  <DataNode TextLabel="Hypoxanthine" GraphId="c0fb4" Type="Metabolite">
    <Graphics CenterX="2019.4736842105272" CenterY="1192.092083058185" Width="80.0" Height="31.951427103969664" ZOrder="34463" FontSize="10" Valign="Middle" Color="0000ff" />
    <Xref Database="KEGG Compound" ID="C00262" />
  </DataNode>
  <DataNode TextLabel="P1,P4-Bis(5'-adenosyl) &#xA;tetraphosphate" GraphId="f0208" Type="Metabolite">
    <Graphics CenterX="3053.0476190476193" CenterY="712.3535108958844" Width="119.0" Height="26.0" ZOrder="34464" FontSize="10" Valign="Middle" Color="0000ff" />
    <Xref Database="KEGG Compound" ID="C01260" />
  </DataNode>
  <DataNode TextLabel="Npr1" GraphId="a140c" Type="GeneProduct" GroupRef="e83ec">
    <Comment Source="KeggConverter">Original kegg element: gene;243;mmu:14917 mmu:14918 mmu:14919 mmu:18160 mmu:230103 mmu:234889 mmu:239134 mmu:245650 mmu:54195 mmu:60596</Comment>
    <Graphics CenterX="263.6371674701754" CenterY="715.4877239289052" Width="80.0" Height="20.0" ZOrder="34465" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="18160" />
  </DataNode>
  <DataNode TextLabel="Ak4" GraphId="eef05" Type="GeneProduct" GroupRef="d54ef">
    <Comment Source="KeggConverter">Original kegg element: gene;285;mmu:11636 mmu:11637 mmu:11639 mmu:229949 mmu:78801</Comment>
    <Graphics CenterX="2601.0373715597634" CenterY="1055.7173004204114" Width="80.0" Height="20.0" ZOrder="34466" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="11639" />
  </DataNode>
  <DataNode TextLabel="Pnp" GraphId="b9fad" Type="GeneProduct" GroupRef="b805f">
    <Comment Source="KeggConverter">Original kegg element: gene;211;mmu:18950 mmu:667034</Comment>
    <Graphics CenterX="2124.2105263157887" CenterY="1106.3835860838537" Width="80.0" Height="20.0" ZOrder="34467" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="18950" />
  </DataNode>
  <DataNode TextLabel="Pgm1" GraphId="a2004" Type="GeneProduct" GroupRef="ba84c">
    <Comment Source="KeggConverter">Original kegg element: gene;431;mmu:66681 mmu:72157</Comment>
    <Graphics CenterX="223.02985074626872" CenterY="196.396154819125" Width="80.0" Height="20.0" ZOrder="34468" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="66681" />
  </DataNode>
  <DataNode TextLabel="Pde9a" GraphId="efc13" Type="GeneProduct" GroupRef="e4165">
    <Comment Source="KeggConverter">Original kegg element: gene;245;mmu:110385 mmu:110855 mmu:18573 mmu:18574 mmu:18575 mmu:18576 mmu:18577 mmu:18578 mmu:18582 mmu:18583 mmu:18584 mmu:18585 mmu:18587 mmu:18588 mmu:207728 mmu:218461 mmu:225600 mmu:238871 mmu:23984 mmu:241489 mmu:242202 mmu:29863 mmu:54611 mmu:78600</Comment>
    <Graphics CenterX="141.79898241873565" CenterY="643.8574623569884" Width="80.0" Height="20.0" ZOrder="34469" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="18585" />
  </DataNode>
  <DataNode TextLabel="Cant1" GraphId="cba2c" Type="GeneProduct" GroupRef="add34">
    <Comment Source="KeggConverter">Original kegg element: gene;205;mmu:12497 mmu:12499 mmu:67464 mmu:76025</Comment>
    <Graphics CenterX="1252.3682864450127" CenterY="633.868308119121" Width="80.0" Height="20.0" ZOrder="34470" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="76025" />
  </DataNode>
  <DataNode TextLabel="Adcy9" GraphId="ca4d3" Type="GeneProduct" GroupRef="ae4c5">
    <Comment Source="KeggConverter">Original kegg element: gene;297;mmu:104110 mmu:104111 mmu:11512 mmu:11513 mmu:11514 mmu:11515 mmu:210044 mmu:224129 mmu:271639 mmu:432530</Comment>
    <Graphics CenterX="369.7182662538706" CenterY="693.7456805784038" Width="80.0" Height="20.0" ZOrder="34471" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="11515" />
  </DataNode>
  <DataNode TextLabel="Nt5c1b" GraphId="bcafb" Type="GeneProduct" GroupRef="e7a69">
    <Comment Source="KeggConverter">Original kegg element: gene;215;mmu:103850 mmu:107569 mmu:230718 mmu:23959 mmu:50773 mmu:70881 mmu:76952</Comment>
    <Graphics CenterX="1845.196392785571" CenterY="916.0136883937395" Width="80.0" Height="20.0" ZOrder="34472" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="70881" />
  </DataNode>
  <DataNode TextLabel="Nt5c3" GraphId="e5b58" Type="GeneProduct" GroupRef="bad2e">
    <Comment Source="KeggConverter">Original kegg element: gene;182;mmu:103850 mmu:107569 mmu:230718 mmu:23959 mmu:50773 mmu:70881 mmu:76952</Comment>
    <Graphics CenterX="2495.9226519337017" CenterY="882.8598558668041" Width="80.0" Height="20.0" ZOrder="34473" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="107569" />
  </DataNode>
  <DataNode TextLabel="Nt5c" GraphId="a3968" Type="GeneProduct" GroupRef="e7a69">
    <Comment Source="KeggConverter">Original kegg element: gene;215;mmu:103850 mmu:107569 mmu:230718 mmu:23959 mmu:50773 mmu:70881 mmu:76952</Comment>
    <Graphics CenterX="1765.196392785571" CenterY="956.0136883937396" Width="80.0" Height="20.0" ZOrder="34474" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="50773" />
  </DataNode>
  <DataNode TextLabel="Nt5c" GraphId="fe81a" Type="GeneProduct" GroupRef="a692d">
    <Comment Source="KeggConverter">Original kegg element: gene;210;mmu:103850 mmu:107569 mmu:230718 mmu:23959 mmu:50773 mmu:70881 mmu:76952</Comment>
    <Graphics CenterX="1229.3511450381689" CenterY="939.3349721826881" Width="80.0" Height="20.0" ZOrder="34475" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="50773" />
  </DataNode>
  <DataNode TextLabel="Entpd5" GraphId="a913d" Type="GeneProduct" GroupRef="add34">
    <Comment Source="KeggConverter">Original kegg element: gene;205;mmu:12497 mmu:12499 mmu:67464 mmu:76025</Comment>
    <Graphics CenterX="1252.3682864450127" CenterY="653.868308119121" Width="80.0" Height="20.0" ZOrder="34476" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="12499" />
  </DataNode>
  <DataNode TextLabel="Polr2c" GraphId="f0ffd" Type="GeneProduct" GroupRef="c746a">
    <Comment Source="KeggConverter">Original kegg element: gene;241;mmu:100043714 mmu:100046796 mmu:20016 mmu:20017 mmu:20018 mmu:20019 mmu:20020 mmu:20021 mmu:20022 mmu:218832 mmu:231329 mmu:245841 mmu:26939 mmu:625405 mmu:64424 mmu:66136 mmu:66420 mmu:66491 mmu:67005 mmu:67065 mmu:67486 mmu:67710 mmu:69241 mmu:69833 mmu:69870 mmu:69920 mmu:70408 mmu:70428 mmu:74414 mmu:78929</Comment>
    <Graphics CenterX="110.76377692730505" CenterY="1087.6133877981936" Width="92.46225755421065" Height="25.554043353358804" ZOrder="34477" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="20021" />
  </DataNode>
  <DataNode TextLabel="Adcy4" GraphId="e23b9" Type="GeneProduct" GroupRef="ae4c5">
    <Comment Source="KeggConverter">Original kegg element: gene;297;mmu:104110 mmu:104111 mmu:11512 mmu:11513 mmu:11514 mmu:11515 mmu:210044 mmu:224129 mmu:271639 mmu:432530</Comment>
    <Graphics CenterX="369.7182662538706" CenterY="753.7456805784032" Width="80.0" Height="20.0" ZOrder="34478" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="104110" />
  </DataNode>
  <DataNode TextLabel="Pnp" GraphId="eafef" Type="GeneProduct" GroupRef="ee230">
    <Comment Source="KeggConverter">Original kegg element: gene;188;mmu:18950 mmu:667034</Comment>
    <Graphics CenterX="2696.3640322121446" CenterY="1273.5577172318106" Width="80.0" Height="20.0" ZOrder="34479" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="18950" />
  </DataNode>
  <DataNode TextLabel="Entpd8" GraphId="b7202" Type="GeneProduct" GroupRef="eedcd">
    <Comment Source="KeggConverter">Original kegg element: gene;171;mmu:12495 mmu:215446 mmu:72090</Comment>
    <Graphics CenterX="2807.944751381217" CenterY="717.0070231295073" Width="80.0" Height="20.0" ZOrder="34480" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="72090" />
  </DataNode>
  <DataNode TextLabel="NH₃" GraphId="a3fe9" Type="Metabolite">
    <Graphics CenterX="2116.0677966101694" CenterY="708.35593220339" Width="80.0" Height="20.0" ZOrder="34481" FontSize="10" Valign="Middle" Color="0000ff" />
    <Xref Database="KEGG Compound" ID="C00014" />
  </DataNode>
  <DataNode TextLabel="Nt5c1a" GraphId="df41f" Type="GeneProduct" GroupRef="a692d">
    <Comment Source="KeggConverter">Original kegg element: gene;210;mmu:103850 mmu:107569 mmu:230718 mmu:23959 mmu:50773 mmu:70881 mmu:76952</Comment>
    <Graphics CenterX="1229.3511450381689" CenterY="919.334972182688" Width="80.0" Height="20.0" ZOrder="34482" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="230718" />
  </DataNode>
  <DataNode TextLabel="Pde4b" GraphId="f1d4b" Type="GeneProduct" GroupRef="e4165">
    <Comment Source="KeggConverter">Original kegg element: gene;245;mmu:110385 mmu:110855 mmu:18573 mmu:18574 mmu:18575 mmu:18576 mmu:18577 mmu:18578 mmu:18582 mmu:18583 mmu:18584 mmu:18585 mmu:18587 mmu:18588 mmu:207728 mmu:218461 mmu:225600 mmu:238871 mmu:23984 mmu:241489 mmu:242202 mmu:29863 mmu:54611 mmu:78600</Comment>
    <Graphics CenterX="141.79898241873565" CenterY="683.8574623569884" Width="80.0" Height="20.0" ZOrder="34483" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="18578" />
  </DataNode>
  <DataNode TextLabel="dGTP" GraphId="ca13d" Type="Metabolite">
    <Graphics CenterX="737.2710997442449" CenterY="946.0677966101696" Width="80.0" Height="31.951427103969802" ZOrder="34484" FontSize="10" Valign="Middle" Color="0000ff" />
    <Xref Database="KEGG Compound" ID="C00286" />
  </DataNode>
  <DataNode TextLabel="Nt5c1b" GraphId="de74a" Type="GeneProduct" GroupRef="b56f8">
    <Comment Source="KeggConverter">Original kegg element: gene;192;mmu:103850 mmu:107569 mmu:230718 mmu:23959 mmu:50773 mmu:70881 mmu:76952</Comment>
    <Graphics CenterX="2104.3973483326718" CenterY="828.7660690087237" Width="80.0" Height="20.0" ZOrder="34485" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="70881" />
  </DataNode>
  <DataNode TextLabel="Entpd1" GraphId="d5b82" Type="GeneProduct" GroupRef="d409a">
    <Comment Source="KeggConverter">Original kegg element: gene;234;mmu:12495 mmu:215446 mmu:72090</Comment>
    <Graphics CenterX="919.6317135549864" CenterY="691.3465689886862" Width="80.0" Height="20.0" ZOrder="34486" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="12495" />
  </DataNode>
  <DataNode TextLabel="Entpd8" GraphId="ef245" Type="GeneProduct" GroupRef="e2820">
    <Comment Source="KeggConverter">Original kegg element: gene;177;mmu:12495 mmu:215446 mmu:72090</Comment>
    <Graphics CenterX="2613.9496230029104" CenterY="868.5375759478502" Width="80.0" Height="20.0" ZOrder="34487" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="72090" />
  </DataNode>
  <DataNode TextLabel="P1,P4-Bis(5'-guanosyl) &#xA;tetraphosphate" GraphId="d5f73" Type="Metabolite">
    <Comment>aka GppppG</Comment>
    <Graphics CenterX="640.0" CenterY="910.5338983050848" Width="118.0" Height="28.93220338983042" ZOrder="34488" FontSize="10" Valign="Middle" Color="0000ff" />
    <Xref Database="KEGG Compound" ID="C01261" />
  </DataNode>
  <DataNode TextLabel="Pde1c" GraphId="f2155" Type="GeneProduct" GroupRef="f5806">
    <Comment Source="KeggConverter">Original kegg element: gene;165;mmu:110385 mmu:18573 mmu:18574 mmu:18575 mmu:18576 mmu:18577 mmu:18578 mmu:18583 mmu:18584 mmu:207728 mmu:218461 mmu:238871 mmu:23984 mmu:241489 mmu:29863 mmu:54611</Comment>
    <Graphics CenterX="2633.2557883131203" CenterY="308.09536000597984" Width="80.0" Height="20.0" ZOrder="34489" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="18575" />
  </DataNode>
  <DataNode TextLabel="Polr1e" GraphId="ae6f5" Type="GeneProduct" GroupRef="c746a">
    <Comment Source="KeggConverter">Original kegg element: gene;241;mmu:100043714 mmu:100046796 mmu:20016 mmu:20017 mmu:20018 mmu:20019 mmu:20020 mmu:20021 mmu:20022 mmu:218832 mmu:231329 mmu:245841 mmu:26939 mmu:625405 mmu:64424 mmu:66136 mmu:66420 mmu:66491 mmu:67005 mmu:67065 mmu:67486 mmu:67710 mmu:69241 mmu:69833 mmu:69870 mmu:69920 mmu:70408 mmu:70428 mmu:74414 mmu:78929</Comment>
    <Graphics CenterX="204.2166917255102" CenterY="1112.4200469960965" Width="92.46225755421065" Height="25.554043353358804" ZOrder="34490" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="64424" />
  </DataNode>
  <DataNode TextLabel="N6-(1,2-Dicarboxyethyl)-AMP" GraphId="ea57c" Type="Metabolite">
    <Comment>aka adenylosuccinate</Comment>
    <Graphics CenterX="2168.5" CenterY="548.0677966101696" Width="143.0" Height="20.0" ZOrder="34491" FontSize="10" Valign="Middle" Color="0000ff" />
    <Xref Database="KEGG Compound" ID="C03794" />
  </DataNode>
  <DataNode TextLabel="Adcy7" GraphId="feafe" Type="GeneProduct" GroupRef="ae4c5">
    <Comment Source="KeggConverter">Original kegg element: gene;297;mmu:104110 mmu:104111 mmu:11512 mmu:11513 mmu:11514 mmu:11515 mmu:210044 mmu:224129 mmu:271639 mmu:432530</Comment>
    <Graphics CenterX="369.7182662538706" CenterY="713.7456805784035" Width="80.0" Height="20.0" ZOrder="34492" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="11513" />
  </DataNode>
  <DataNode TextLabel="Nt5c1a" GraphId="bdfd1" Type="GeneProduct" GroupRef="e7a69">
    <Comment Source="KeggConverter">Original kegg element: gene;215;mmu:103850 mmu:107569 mmu:230718 mmu:23959 mmu:50773 mmu:70881 mmu:76952</Comment>
    <Graphics CenterX="1765.196392785571" CenterY="936.0136883937391" Width="80.0" Height="20.0" ZOrder="34493" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="230718" />
  </DataNode>
  <DataNode TextLabel="Xdh" GraphId="cee76" Type="GeneProduct">
    <Comment Source="KeggConverter">Original kegg element: gene;136;mmu:22436</Comment>
    <Graphics CenterX="1841.9871604681198" CenterY="1302.9376054920021" Width="80.0" Height="20.0" ZOrder="34494" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="22436" />
  </DataNode>
  <DataNode TextLabel="Pde2a" GraphId="e9711" Type="GeneProduct" GroupRef="f5806">
    <Comment Source="KeggConverter">Original kegg element: gene;165;mmu:110385 mmu:18573 mmu:18574 mmu:18575 mmu:18576 mmu:18577 mmu:18578 mmu:18583 mmu:18584 mmu:207728 mmu:218461 mmu:238871 mmu:23984 mmu:241489 mmu:29863 mmu:54611</Comment>
    <Graphics CenterX="2633.2557883131203" CenterY="248.09536000597984" Width="80.0" Height="20.0" ZOrder="34495" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="207728" />
  </DataNode>
  <DataNode TextLabel="Itpa" GraphId="da38d" Type="GeneProduct">
    <Comment Source="KeggConverter">Original kegg element: gene;294;mmu:16434</Comment>
    <Graphics CenterX="1068.7453142227118" CenterY="437.68190906882467" Width="80.0" Height="20.0" ZOrder="34496" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="16434" />
  </DataNode>
  <DataNode TextLabel="Znrd1" GraphId="da3a8" Type="GeneProduct" GroupRef="c746a">
    <Comment Source="KeggConverter">Original kegg element: gene;241;mmu:100043714 mmu:100046796 mmu:20016 mmu:20017 mmu:20018 mmu:20019 mmu:20020 mmu:20021 mmu:20022 mmu:218832 mmu:231329 mmu:245841 mmu:26939 mmu:625405 mmu:64424 mmu:66136 mmu:66420 mmu:66491 mmu:67005 mmu:67065 mmu:67486 mmu:67710 mmu:69241 mmu:69833 mmu:69870 mmu:69920 mmu:70408 mmu:70428 mmu:74414 mmu:78929</Comment>
    <Graphics CenterX="19.048068185003256" CenterY="1240.7213095244317" Width="92.46225755421057" Height="25.554043353358804" ZOrder="34497" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="66136" />
  </DataNode>
  <DataNode TextLabel="5-hydroxy-2-oxo&#xA;4-ureido-2,5-dihydro&#xA;1H-imidazole-&#xA;5-carbozylate" GraphId="c9878" Type="Metabolite">
    <Graphics CenterX="1836.774891774892" CenterY="1496.0297894196221" Width="102.03463203463247" Height="54.54545454545459" ZOrder="34498" FontSize="10" Valign="Middle" Color="0000ff" />
    <Xref Database="KEGG Compound" ID="C12248" />
  </DataNode>
  <DataNode TextLabel="Polr2h" GraphId="b0600" Type="GeneProduct" GroupRef="c746a">
    <Comment Source="KeggConverter">Original kegg element: gene;241;mmu:100043714 mmu:100046796 mmu:20016 mmu:20017 mmu:20018 mmu:20019 mmu:20020 mmu:20021 mmu:20022 mmu:218832 mmu:231329 mmu:245841 mmu:26939 mmu:625405 mmu:64424 mmu:66136 mmu:66420 mmu:66491 mmu:67005 mmu:67065 mmu:67486 mmu:67710 mmu:69241 mmu:69833 mmu:69870 mmu:69920 mmu:70408 mmu:70428 mmu:74414 mmu:78929</Comment>
    <Graphics CenterX="19.048068185003256" CenterY="1291.82939623115" Width="92.46225755421057" Height="25.554043353358804" ZOrder="34499" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="245841" />
  </DataNode>
  <DataNode TextLabel="adenosine" GraphId="f6312" Type="Metabolite">
    <Graphics CenterX="2402.0" CenterY="980.0677966101696" Width="80.0" Height="20.0" ZOrder="34500" FontSize="10" Valign="Middle" Color="0000ff" />
    <Xref Database="KEGG Compound" ID="C00212" />
  </DataNode>
  <DataNode TextLabel="1-(5'-Phosphoribosyl)-5-amino-4-&#xA;(N-succinocarboxamide)-imidazole" GraphId="a9efa" Type="Metabolite">
    <Graphics CenterX="1811.971786833857" CenterY="234.21356463524796" Width="163.88087774294695" Height="31.0" ZOrder="34501" FontSize="10" Valign="Middle" Color="0000ff" />
    <Xref Database="KEGG Compound" ID="C04823" />
  </DataNode>
  <DataNode TextLabel="Polr1a" GraphId="e0f11" Type="GeneProduct" GroupRef="c746a">
    <Comment Source="KeggConverter">Original kegg element: gene;241;mmu:100043714 mmu:100046796 mmu:20016 mmu:20017 mmu:20018 mmu:20019 mmu:20020 mmu:20021 mmu:20022 mmu:218832 mmu:231329 mmu:245841 mmu:26939 mmu:625405 mmu:64424 mmu:66136 mmu:66420 mmu:66491 mmu:67005 mmu:67065 mmu:67486 mmu:67710 mmu:69241 mmu:69833 mmu:69870 mmu:69920 mmu:70408 mmu:70428 mmu:74414 mmu:78929</Comment>
    <Graphics CenterX="110.76377692730505" CenterY="1113.1674311515524" Width="92.46225755421065" Height="25.554043353358804" ZOrder="34502" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="20019" />
  </DataNode>
  <DataNode TextLabel="Prim2" GraphId="ba498" Type="GeneProduct" GroupRef="fc208">
    <Comment Source="KeggConverter">Original kegg element: gene;244;mmu:18968 mmu:18969 mmu:18971 mmu:18972 mmu:18973 mmu:18974 mmu:19075 mmu:19076 mmu:59001 mmu:66979 mmu:67967 mmu:69745</Comment>
    <Graphics CenterX="559.8185588616717" CenterY="1035.2514700795577" Width="80.0" Height="20.0" ZOrder="34503" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="19076" />
  </DataNode>
  <DataNode TextLabel="Nt5c" GraphId="ba89b" Type="GeneProduct" GroupRef="e79b1">
    <Comment Source="KeggConverter">Original kegg element: gene;186;mmu:103850 mmu:107569 mmu:230718 mmu:23959 mmu:50773 mmu:70881 mmu:76952</Comment>
    <Graphics CenterX="2909.0679910424597" CenterY="1189.8317654384516" Width="80.0" Height="20.0" ZOrder="34504" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="50773" />
  </DataNode>
  <DataNode TextLabel="Ampd3" GraphId="d5085" Type="GeneProduct" GroupRef="ad6d1">
    <Comment Source="KeggConverter">Original kegg element: gene;181;mmu:109674 mmu:11717 mmu:229665</Comment>
    <Graphics CenterX="2202.083969465647" CenterY="690.1465260706433" Width="80.0" Height="21.44559451416785" ZOrder="34505" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="11717" />
  </DataNode>
  <DataNode TextLabel="Folate &#xA;biosynthesis" GraphId="bfdb2" Type="Pathway">
    <Comment Source="KeggConverter">Original kegg element: map;253;path:mmu00790</Comment>
    <Graphics CenterX="305.51270553064273" CenterY="953.773808618985" Width="82.0" Height="29.9322033898304" ZOrder="34507" FontWeight="Bold" FontSize="10" Valign="Middle" Color="14961e" />
    <Xref Database="WikiPathways" ID="WP1273" />
  </DataNode>
  <DataNode TextLabel="Entpd1" GraphId="d0043" Type="GeneProduct" GroupRef="eedcd">
    <Comment Source="KeggConverter">Original kegg element: gene;171;mmu:12495 mmu:215446 mmu:72090</Comment>
    <Graphics CenterX="2807.944751381217" CenterY="697.0070231295073" Width="80.0" Height="20.0" ZOrder="34508" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="12495" />
  </DataNode>
  <DataNode TextLabel="Adcy3" GraphId="f0179" Type="GeneProduct" GroupRef="ae4c5">
    <Comment Source="KeggConverter">Original kegg element: gene;297;mmu:104110 mmu:104111 mmu:11512 mmu:11513 mmu:11514 mmu:11515 mmu:210044 mmu:224129 mmu:271639 mmu:432530</Comment>
    <Graphics CenterX="369.7182662538706" CenterY="733.7456805784034" Width="80.0" Height="20.0" ZOrder="34509" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="104111" />
  </DataNode>
  <DataNode TextLabel="Nt5c3" GraphId="f5221" Type="GeneProduct" GroupRef="e7a69">
    <Comment Source="KeggConverter">Original kegg element: gene;215;mmu:103850 mmu:107569 mmu:230718 mmu:23959 mmu:50773 mmu:70881 mmu:76952</Comment>
    <Graphics CenterX="1845.196392785571" CenterY="956.0136883937396" Width="80.0" Height="20.0" ZOrder="34510" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="107569" />
  </DataNode>
  <DataNode TextLabel="Adsl" GraphId="b4b60" Type="GeneProduct">
    <Comment Source="KeggConverter">Original kegg element: gene;179;mmu:11564</Comment>
    <Graphics CenterX="2344.0" CenterY="563.0677966101696" Width="80.0" Height="20.0" ZOrder="34511" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="11564" />
  </DataNode>
  <DataNode TextLabel="AMP" GraphId="e1720" Type="Metabolite">
    <Graphics CenterX="2402.0" CenterY="792.3258611262991" Width="80.0000000000001" Height="25.660874519299288" ZOrder="34512" FontSize="10" Valign="Middle" Color="0000ff" />
    <Xref Database="KEGG Compound" ID="C00020" />
  </DataNode>
  <DataNode TextLabel="P1,P3-Bis(5'-adenosyl) &#xA;triphosphate" GraphId="adef9" Type="Metabolite">
    <Graphics CenterX="2654.4608599779494" CenterY="496.852250854932" Width="114.0" Height="29.0" ZOrder="34513" FontSize="10" Valign="Middle" Color="0000ff" />
    <Xref Database="KEGG Compound" ID="C06197" />
  </DataNode>
  <DataNode TextLabel="Impdh1" GraphId="c6153" Type="GeneProduct" GroupRef="ca3c6">
    <Comment Source="KeggConverter">Original kegg element: gene;201;mmu:100042069 mmu:23917 mmu:23918</Comment>
    <Graphics CenterX="1844.3030303030296" CenterY="834.1890087313819" Width="80.0" Height="20.0" ZOrder="34514" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="23917" />
  </DataNode>
  <DataNode TextLabel="Pold2" GraphId="ae187" Type="GeneProduct" GroupRef="fc208">
    <Comment Source="KeggConverter">Original kegg element: gene;244;mmu:18968 mmu:18969 mmu:18971 mmu:18972 mmu:18973 mmu:18974 mmu:19075 mmu:19076 mmu:59001 mmu:66979 mmu:67967 mmu:69745</Comment>
    <Graphics CenterX="561.0973312401883" CenterY="1075.2514700795577" Width="80.0" Height="20.0" ZOrder="34515" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="18972" />
  </DataNode>
  <DataNode TextLabel="Nt5e" GraphId="dc855" Type="GeneProduct" GroupRef="bad2e">
    <Comment Source="KeggConverter">Original kegg element: gene;182;mmu:103850 mmu:107569 mmu:230718 mmu:23959 mmu:50773 mmu:70881 mmu:76952</Comment>
    <Graphics CenterX="2495.9226519337017" CenterY="862.8598558668036" Width="80.0" Height="20.0" ZOrder="34516" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="23959" />
  </DataNode>
  <DataNode TextLabel="Nt5m" GraphId="a6251" Type="GeneProduct" GroupRef="b56f8">
    <Comment Source="KeggConverter">Original kegg element: gene;192;mmu:103850 mmu:107569 mmu:230718 mmu:23959 mmu:50773 mmu:70881 mmu:76952</Comment>
    <Graphics CenterX="2104.3973483326718" CenterY="888.7660690087248" Width="80.0" Height="20.0" ZOrder="34517" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="103850" />
  </DataNode>
  <DataNode TextLabel="Polr3k" GraphId="e3c20" Type="GeneProduct" GroupRef="afea2">
    <Comment Source="KeggConverter">Original kegg element: gene;168;mmu:100043714 mmu:100046796 mmu:20016 mmu:20017 mmu:20018 mmu:20019 mmu:20020 mmu:20021 mmu:20022 mmu:218832 mmu:231329 mmu:245841 mmu:26939 mmu:625405 mmu:64424 mmu:66136 mmu:66420 mmu:66491 mmu:67005 mmu:67065 mmu:67486 mmu:67710 mmu:69241 mmu:69833 mmu:69870 mmu:69920 mmu:70408 mmu:70428 mmu:74414 mmu:78929</Comment>
    <Graphics CenterX="3386.1100751994018" CenterY="599.1702473823411" Width="90.94297214511298" Height="23.592612772064896" ZOrder="34518" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="67005" />
  </DataNode>
  <DataNode TextLabel="P1,P4-Bis(5'-xanthosyl) &#xA;tetraphosphate" GraphId="a26d8" Type="Metabolite">
    <Comment>aka XppppX</Comment>
    <Graphics CenterX="1435.6755725190858" CenterY="879.8717169103386" Width="114.70992366412207" Height="28.208953292793467" ZOrder="34519" FontSize="10" Valign="Middle" Color="0000ff" />
    <Xref Database="KEGG Compound" ID="C04392" />
  </DataNode>
  <DataNode TextLabel="Pde6c" GraphId="b305d" Type="GeneProduct" GroupRef="e4165">
    <Comment Source="KeggConverter">Original kegg element: gene;245;mmu:110385 mmu:110855 mmu:18573 mmu:18574 mmu:18575 mmu:18576 mmu:18577 mmu:18578 mmu:18582 mmu:18583 mmu:18584 mmu:18585 mmu:18587 mmu:18588 mmu:207728 mmu:218461 mmu:225600 mmu:238871 mmu:23984 mmu:241489 mmu:242202 mmu:29863 mmu:54611 mmu:78600</Comment>
    <Graphics CenterX="141.79898241873565" CenterY="743.8574623569884" Width="80.0" Height="20.0" ZOrder="34521" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="110855" />
  </DataNode>
  <DataNode TextLabel="Pklr" GraphId="acb0e" Type="GeneProduct" GroupRef="b81f1">
    <Comment Source="KeggConverter">Original kegg element: gene;310;mmu:18746 mmu:18770</Comment>
    <Graphics CenterX="2831.15545755237" CenterY="987.9641582419229" Width="80.0" Height="20.0" ZOrder="34522" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="18770" />
  </DataNode>
  <DataNode TextLabel="Pde10a" GraphId="da85b" Type="GeneProduct" GroupRef="e4165">
    <Comment Source="KeggConverter">Original kegg element: gene;245;mmu:110385 mmu:110855 mmu:18573 mmu:18574 mmu:18575 mmu:18576 mmu:18577 mmu:18578 mmu:18582 mmu:18583 mmu:18584 mmu:18585 mmu:18587 mmu:18588 mmu:207728 mmu:218461 mmu:225600 mmu:238871 mmu:23984 mmu:241489 mmu:242202 mmu:29863 mmu:54611 mmu:78600</Comment>
    <Graphics CenterX="141.79898241873565" CenterY="943.8574623569881" Width="80.0" Height="20.0" ZOrder="34523" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="23984" />
  </DataNode>
  <DataNode TextLabel="Paics" GraphId="f6269" Type="GeneProduct">
    <Comment Source="KeggConverter">Original kegg element: gene;161;mmu:67054</Comment>
    <Graphics CenterX="1688.5956112852668" CenterY="186.40008501142376" Width="80.0" Height="20.0" ZOrder="34524" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="67054" />
  </DataNode>
  <DataNode TextLabel="5'-Phosphoribosyl-N-&#xA;formylglycinamide" GraphId="ce5fb" Type="Metabolite">
    <Graphics CenterX="1047.420062695926" CenterY="234.35933266032634" Width="104.9968652037629" Height="27.416927899686485" ZOrder="34525" FontSize="10" Valign="Middle" Color="0000ff" />
    <Xref Database="KEGG Compound" ID="C04376" />
  </DataNode>
  <DataNode TextLabel="Prps1l3" GraphId="d23b0" Type="GeneProduct" GroupRef="ad65e">
    <Comment Source="KeggConverter">Original kegg element: gene;153;mmu:110639 mmu:19139 mmu:328099 mmu:75456</Comment>
    <Graphics CenterX="391.9686520376172" CenterY="201.03958344402525" Width="80.0" Height="20.0" ZOrder="34526" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="328099" />
  </DataNode>
  <DataNode TextLabel="Polr3e" GraphId="f5eb4" Type="GeneProduct" GroupRef="afea2">
    <Comment Source="KeggConverter">Original kegg element: gene;168;mmu:100043714 mmu:100046796 mmu:20016 mmu:20017 mmu:20018 mmu:20019 mmu:20020 mmu:20021 mmu:20022 mmu:218832 mmu:231329 mmu:245841 mmu:26939 mmu:625405 mmu:64424 mmu:66136 mmu:66420 mmu:66491 mmu:67005 mmu:67065 mmu:67486 mmu:67710 mmu:69241 mmu:69833 mmu:69870 mmu:69920 mmu:70408 mmu:70428 mmu:74414 mmu:78929</Comment>
    <Graphics CenterX="3386.1100751994018" CenterY="528.3924090661465" Width="90.94297214511298" Height="23.592612772064896" ZOrder="34527" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="26939" />
  </DataNode>
  <DataNode TextLabel="Entpd3" GraphId="cb6e1" Type="GeneProduct" GroupRef="eedcd">
    <Comment Source="KeggConverter">Original kegg element: gene;171;mmu:12495 mmu:215446 mmu:72090</Comment>
    <Graphics CenterX="2807.944751381217" CenterY="677.0070231295073" Width="80.0" Height="20.0" ZOrder="34528" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="215446" />
  </DataNode>
  <DataNode TextLabel="Polr3f" GraphId="d5d07" Type="GeneProduct" GroupRef="afea2">
    <Comment Source="KeggConverter">Original kegg element: gene;168;mmu:100043714 mmu:100046796 mmu:20016 mmu:20017 mmu:20018 mmu:20019 mmu:20020 mmu:20021 mmu:20022 mmu:218832 mmu:231329 mmu:245841 mmu:26939 mmu:625405 mmu:64424 mmu:66136 mmu:66420 mmu:66491 mmu:67005 mmu:67065 mmu:67486 mmu:67710 mmu:69241 mmu:69833 mmu:69870 mmu:69920 mmu:70408 mmu:70428 mmu:74414 mmu:78929</Comment>
    <Graphics CenterX="3386.1100751994018" CenterY="693.5406984706007" Width="90.94297214511298" Height="23.592612772064896" ZOrder="34529" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="70408" />
  </DataNode>
  <DataNode TextLabel="ADP" GraphId="a847d" Type="Metabolite">
    <Graphics CenterX="2727.9999999999995" CenterY="792.3258611262991" Width="80.0" Height="25.660874519299245" ZOrder="34530" FontSize="10" Valign="Middle" Color="0000ff" />
    <Xref Database="KEGG Compound" ID="C00008" />
  </DataNode>
  <DataNode TextLabel="Nme7" GraphId="bb9c5" Type="GeneProduct" GroupRef="cf79b">
    <Comment Source="KeggConverter">Original kegg element: gene;175;mmu:171567 mmu:18102 mmu:18103 mmu:54369 mmu:56520 mmu:75533 mmu:79059</Comment>
    <Graphics CenterX="2941.409040793826" CenterY="1052.2706632033337" Width="80.0" Height="20.0" ZOrder="34531" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="171567" />
  </DataNode>
  <DataNode TextLabel="Pde3b" GraphId="aab19" Type="GeneProduct" GroupRef="e4165">
    <Comment Source="KeggConverter">Original kegg element: gene;245;mmu:110385 mmu:110855 mmu:18573 mmu:18574 mmu:18575 mmu:18576 mmu:18577 mmu:18578 mmu:18582 mmu:18583 mmu:18584 mmu:18585 mmu:18587 mmu:18588 mmu:207728 mmu:218461 mmu:225600 mmu:238871 mmu:23984 mmu:241489 mmu:242202 mmu:29863 mmu:54611 mmu:78600</Comment>
    <Graphics CenterX="141.79898241873565" CenterY="703.8574623569884" Width="80.0" Height="20.0" ZOrder="34532" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="18576" />
  </DataNode>
  <DataNode TextLabel="Ak2" GraphId="f1592" Type="GeneProduct" GroupRef="b11a0">
    <Comment Source="KeggConverter">Original kegg element: gene;178;mmu:11636 mmu:11637 mmu:11639 mmu:229949 mmu:78801</Comment>
    <Graphics CenterX="2514.2679558011055" CenterY="662.2124028467089" Width="80.0000000000001" Height="20.000000000000025" ZOrder="34533" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="11637" />
  </DataNode>
  <DataNode TextLabel="Polr3a" GraphId="f4fe4" Type="GeneProduct" GroupRef="afea2">
    <Comment Source="KeggConverter">Original kegg element: gene;168;mmu:100043714 mmu:100046796 mmu:20016 mmu:20017 mmu:20018 mmu:20019 mmu:20020 mmu:20021 mmu:20022 mmu:218832 mmu:231329 mmu:245841 mmu:26939 mmu:625405 mmu:64424 mmu:66136 mmu:66420 mmu:66491 mmu:67005 mmu:67065 mmu:67486 mmu:67710 mmu:69241 mmu:69833 mmu:69870 mmu:69920 mmu:70408 mmu:70428 mmu:74414 mmu:78929</Comment>
    <Graphics CenterX="3295.1671030542893" CenterY="504.7997962940815" Width="90.94297214511298" Height="23.592612772064896" ZOrder="34534" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="218832" />
  </DataNode>
  <DataNode TextLabel="Polr3b" GraphId="fe7a8" Type="GeneProduct" GroupRef="afea2">
    <Comment Source="KeggConverter">Original kegg element: gene;168;mmu:100043714 mmu:100046796 mmu:20016 mmu:20017 mmu:20018 mmu:20019 mmu:20020 mmu:20021 mmu:20022 mmu:218832 mmu:231329 mmu:245841 mmu:26939 mmu:625405 mmu:64424 mmu:66136 mmu:66420 mmu:66491 mmu:67005 mmu:67065 mmu:67486 mmu:67710 mmu:69241 mmu:69833 mmu:69870 mmu:69920 mmu:70408 mmu:70428 mmu:74414 mmu:78929</Comment>
    <Graphics CenterX="3204.224130909176" CenterY="528.3924090661465" Width="90.94297214511298" Height="23.592612772064896" ZOrder="34535" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="70428" />
  </DataNode>
  <DataNode TextLabel="alpha-D-Ribose 1-phosphate" GraphId="dab45" Type="Metabolite">
    <Graphics CenterX="117.95522388059706" CenterY="234.35933266032634" Width="139.19402985074626" Height="20.0" ZOrder="34536" FontSize="10" Valign="Middle" Color="0000ff" />
    <Xref Database="KEGG Compound" ID="C00620" />
  </DataNode>
  <DataNode TextLabel="Adcy1" GraphId="d2823" Type="GeneProduct" GroupRef="e3f1d">
    <Comment Source="KeggConverter">Original kegg element: gene;166;mmu:104110 mmu:104111 mmu:11512 mmu:11513 mmu:11514 mmu:11515 mmu:210044 mmu:224129 mmu:271639 mmu:432530</Comment>
    <Graphics CenterX="3525.0385742900316" CenterY="542.0706628646265" Width="80.0" Height="20.0" ZOrder="34537" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="432530" />
  </DataNode>
  <DataNode TextLabel="Ppat" GraphId="e73e9" Type="GeneProduct">
    <Comment Source="KeggConverter">Original kegg element: gene;154;mmu:231327</Comment>
    <Graphics CenterX="593.6238244514101" CenterY="186.40008501142376" Width="80.0" Height="20.0" ZOrder="34538" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="231327" />
  </DataNode>
  <DataNode TextLabel="Polr2h" GraphId="a79f4" Type="GeneProduct" GroupRef="afea2">
    <Comment Source="KeggConverter">Original kegg element: gene;168;mmu:100043714 mmu:100046796 mmu:20016 mmu:20017 mmu:20018 mmu:20019 mmu:20020 mmu:20021 mmu:20022 mmu:218832 mmu:231329 mmu:245841 mmu:26939 mmu:625405 mmu:64424 mmu:66136 mmu:66420 mmu:66491 mmu:67005 mmu:67065 mmu:67486 mmu:67710 mmu:69241 mmu:69833 mmu:69870 mmu:69920 mmu:70408 mmu:70428 mmu:74414 mmu:78929</Comment>
    <Graphics CenterX="3204.224130909176" CenterY="717.1333112426655" Width="90.94297214511298" Height="23.592612772064896" ZOrder="34539" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="245841" />
  </DataNode>
  <DataNode TextLabel="Adcy4" GraphId="ae1b1" Type="GeneProduct" GroupRef="e3f1d">
    <Comment Source="KeggConverter">Original kegg element: gene;166;mmu:104110 mmu:104111 mmu:11512 mmu:11513 mmu:11514 mmu:11515 mmu:210044 mmu:224129 mmu:271639 mmu:432530</Comment>
    <Graphics CenterX="3525.0385742900316" CenterY="642.0706628646263" Width="80.0" Height="20.0" ZOrder="34540" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="104110" />
  </DataNode>
  <DataNode TextLabel="Entpd5" GraphId="c2921" Type="GeneProduct" GroupRef="fc1ac">
    <Comment Source="KeggConverter">Original kegg element: gene;303;mmu:12497 mmu:12499 mmu:67464 mmu:76025</Comment>
    <Graphics CenterX="1882.5454545454545" CenterY="649.1587057010789" Width="80.0" Height="20.0" ZOrder="34541" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="12499" />
  </DataNode>
  <DataNode TextLabel="Nt5e" GraphId="ac62c" Type="GeneProduct" GroupRef="a692d">
    <Comment Source="KeggConverter">Original kegg element: gene;210;mmu:103850 mmu:107569 mmu:230718 mmu:23959 mmu:50773 mmu:70881 mmu:76952</Comment>
    <Graphics CenterX="1229.3511450381689" CenterY="859.3349721826895" Width="80.0" Height="20.0" ZOrder="34542" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="23959" />
  </DataNode>
  <DataNode TextLabel="Pold1" GraphId="c6eea" Type="GeneProduct" GroupRef="fc208">
    <Comment Source="KeggConverter">Original kegg element: gene;244;mmu:18968 mmu:18969 mmu:18971 mmu:18972 mmu:18973 mmu:18974 mmu:19075 mmu:19076 mmu:59001 mmu:66979 mmu:67967 mmu:69745</Comment>
    <Graphics CenterX="641.1601255886964" CenterY="1015.9422079131535" Width="80.0" Height="20.0" ZOrder="34543" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="18971" />
  </DataNode>
  <DataNode TextLabel="Ampd2" GraphId="e764b" Type="GeneProduct" GroupRef="ad6d1">
    <Comment Source="KeggConverter">Original kegg element: gene;181;mmu:109674 mmu:11717 mmu:229665</Comment>
    <Graphics CenterX="2202.083969465647" CenterY="710.8693233277272" Width="80.0" Height="20.0" ZOrder="34544" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="109674" />
  </DataNode>
  <DataNode TextLabel="Polr2e" GraphId="f4a97" Type="GeneProduct" GroupRef="c746a">
    <Comment Source="KeggConverter">Original kegg element: gene;241;mmu:100043714 mmu:100046796 mmu:20016 mmu:20017 mmu:20018 mmu:20019 mmu:20020 mmu:20021 mmu:20022 mmu:218832 mmu:231329 mmu:245841 mmu:26939 mmu:625405 mmu:64424 mmu:66136 mmu:66420 mmu:66491 mmu:67005 mmu:67065 mmu:67486 mmu:67710 mmu:69241 mmu:69833 mmu:69870 mmu:69920 mmu:70408 mmu:70428 mmu:74414 mmu:78929</Comment>
    <Graphics CenterX="204.2166917255102" CenterY="1137.974090349455" Width="92.46225755421065" Height="25.554043353358804" ZOrder="34545" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="66420" />
  </DataNode>
  <DataNode TextLabel="Nudt2" GraphId="f13ac" Type="GeneProduct">
    <Comment Source="KeggConverter">Original kegg element: gene;270;mmu:66401</Comment>
    <Graphics CenterX="3115.9475836994425" CenterY="750.2555459410787" Width="80.0" Height="20.0" ZOrder="34546" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="66401" />
  </DataNode>
  <DataNode TextLabel="Adcy3" GraphId="f2d33" Type="GeneProduct" GroupRef="e3f1d">
    <Comment Source="KeggConverter">Original kegg element: gene;166;mmu:104110 mmu:104111 mmu:11512 mmu:11513 mmu:11514 mmu:11515 mmu:210044 mmu:224129 mmu:271639 mmu:432530</Comment>
    <Graphics CenterX="3525.0385742900316" CenterY="622.0706628646263" Width="80.0" Height="20.0" ZOrder="34548" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="104111" />
  </DataNode>
  <DataNode TextLabel="Guk1" GraphId="e763c" Type="GeneProduct">
    <Comment Source="KeggConverter">Original kegg element: gene;236;mmu:14923</Comment>
    <Graphics CenterX="1074.0779220779207" CenterY="990.3015628439371" Width="80.0" Height="20.0" ZOrder="34549" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="14923" />
  </DataNode>
  <DataNode TextLabel="Pnpt1" GraphId="cfe7e" Type="GeneProduct">
    <Comment Source="KeggConverter">Original kegg element: gene;233;mmu:71701</Comment>
    <Graphics CenterX="1042.0664961636824" CenterY="608.5767480168188" Width="80.0" Height="20.0" ZOrder="34550" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="71701" />
  </DataNode>
  <DataNode TextLabel="Polr3d" GraphId="f8201" Type="GeneProduct" GroupRef="afea2">
    <Comment Source="KeggConverter">Original kegg element: gene;168;mmu:100043714 mmu:100046796 mmu:20016 mmu:20017 mmu:20018 mmu:20019 mmu:20020 mmu:20021 mmu:20022 mmu:218832 mmu:231329 mmu:245841 mmu:26939 mmu:625405 mmu:64424 mmu:66136 mmu:66420 mmu:66491 mmu:67005 mmu:67065 mmu:67486 mmu:67710 mmu:69241 mmu:69833 mmu:69870 mmu:69920 mmu:70408 mmu:70428 mmu:74414 mmu:78929</Comment>
    <Graphics CenterX="3204.224130909176" CenterY="622.762860154406" Width="90.94297214511298" Height="23.592612772064896" ZOrder="34551" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="67065" />
  </DataNode>
  <DataNode TextLabel="Nt5c1b" GraphId="dc7b5" Type="GeneProduct" GroupRef="bad2e">
    <Comment Source="KeggConverter">Original kegg element: gene;182;mmu:103850 mmu:107569 mmu:230718 mmu:23959 mmu:50773 mmu:70881 mmu:76952</Comment>
    <Graphics CenterX="2495.9226519337017" CenterY="842.8598558668041" Width="80.0" Height="20.0" ZOrder="34552" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="70881" />
  </DataNode>
  <DataNode TextLabel="Polr2i" GraphId="f63d0" Type="GeneProduct" GroupRef="afea2">
    <Comment Source="KeggConverter">Original kegg element: gene;168;mmu:100043714 mmu:100046796 mmu:20016 mmu:20017 mmu:20018 mmu:20019 mmu:20020 mmu:20021 mmu:20022 mmu:218832 mmu:231329 mmu:245841 mmu:26939 mmu:625405 mmu:64424 mmu:66136 mmu:66420 mmu:66491 mmu:67005 mmu:67065 mmu:67486 mmu:67710 mmu:69241 mmu:69833 mmu:69870 mmu:69920 mmu:70408 mmu:70428 mmu:74414 mmu:78929</Comment>
    <Graphics CenterX="3204.224130909176" CenterY="551.9850218382113" Width="90.94297214511298" Height="23.592612772064896" ZOrder="34553" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="69920" />
  </DataNode>
  <DataNode TextLabel="Histidine &#xA;metabolism" GraphId="d12bf" Type="Pathway">
    <Comment Source="KeggConverter">Original kegg element: map;151;path:mmu00340</Comment>
    <Graphics CenterX="2019.4736842105272" CenterY="89.06779661016958" Width="84.0" Height="30.0" ZOrder="34554" FontWeight="Bold" FontSize="10" Valign="Middle" Color="14961e" />
    <Xref Database="WikiPathways" ID="WP662" />
  </DataNode>
  <DataNode TextLabel="Gm10774" GraphId="bbeb1" Type="GeneProduct" GroupRef="afea2">
    <Comment Source="KeggConverter">Original kegg element: gene;168;mmu:100043714 mmu:100046796 mmu:20016 mmu:20017 mmu:20018 mmu:20019 mmu:20020 mmu:20021 mmu:20022 mmu:218832 mmu:231329 mmu:245841 mmu:26939 mmu:625405 mmu:64424 mmu:66136 mmu:66420 mmu:66491 mmu:67005 mmu:67065 mmu:67486 mmu:67710 mmu:69241 mmu:69833 mmu:69870 mmu:69920 mmu:70408 mmu:70428 mmu:74414 mmu:78929</Comment>
    <Graphics CenterX="3295.1671030542884" CenterY="622.762860154406" Width="90.94297214511298" Height="23.592612772064896" ZOrder="34555" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="100043714" />
  </DataNode>
  <DataNode TextLabel="Pde6h" GraphId="bd3a4" Type="GeneProduct" GroupRef="e4165">
    <Comment Source="KeggConverter">Original kegg element: gene;245;mmu:110385 mmu:110855 mmu:18573 mmu:18574 mmu:18575 mmu:18576 mmu:18577 mmu:18578 mmu:18582 mmu:18583 mmu:18584 mmu:18585 mmu:18587 mmu:18588 mmu:207728 mmu:218461 mmu:225600 mmu:238871 mmu:23984 mmu:241489 mmu:242202 mmu:29863 mmu:54611 mmu:78600</Comment>
    <Graphics CenterX="141.79898241873565" CenterY="523.8574623569883" Width="80.0" Height="20.0" ZOrder="34557" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="78600" />
  </DataNode>
  <DataNode TextLabel="dGMP" GraphId="eb7d6" Type="Metabolite">
    <Graphics CenterX="997.7316017316018" CenterY="1110.0677966101696" Width="80.00000000000007" Height="31.951427103969714" ZOrder="34558" FontSize="10" Valign="Middle" Color="0000ff" />
    <Xref Database="KEGG Compound" ID="C00362" />
  </DataNode>
  <DataNode TextLabel="Nt5c3" GraphId="c5acd" Type="GeneProduct" GroupRef="a692d">
    <Comment Source="KeggConverter">Original kegg element: gene;210;mmu:103850 mmu:107569 mmu:230718 mmu:23959 mmu:50773 mmu:70881 mmu:76952</Comment>
    <Graphics CenterX="1229.3511450381689" CenterY="879.3349721826888" Width="80.0" Height="20.0" ZOrder="34559" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="107569" />
  </DataNode>
  <DataNode TextLabel="Polr2b" GraphId="e4af2" Type="GeneProduct" GroupRef="c746a">
    <Comment Source="KeggConverter">Original kegg element: gene;241;mmu:100043714 mmu:100046796 mmu:20016 mmu:20017 mmu:20018 mmu:20019 mmu:20020 mmu:20021 mmu:20022 mmu:218832 mmu:231329 mmu:245841 mmu:26939 mmu:625405 mmu:64424 mmu:66136 mmu:66420 mmu:66491 mmu:67005 mmu:67065 mmu:67486 mmu:67710 mmu:69241 mmu:69833 mmu:69870 mmu:69920 mmu:70408 mmu:70428 mmu:74414 mmu:78929</Comment>
    <Graphics CenterX="204.2166917255102" CenterY="1061.311960289379" Width="92.46225755421065" Height="25.554043353358804" ZOrder="34561" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="231329" />
  </DataNode>
  <DataNode TextLabel="Adcy7" GraphId="b184f" Type="GeneProduct" GroupRef="e3f1d">
    <Comment Source="KeggConverter">Original kegg element: gene;166;mmu:104110 mmu:104111 mmu:11512 mmu:11513 mmu:11514 mmu:11515 mmu:210044 mmu:224129 mmu:271639 mmu:432530</Comment>
    <Graphics CenterX="3525.0385742900316" CenterY="602.0706628646263" Width="80.0" Height="20.0" ZOrder="34562" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="11513" />
  </DataNode>
  <DataNode TextLabel="Polr2g" GraphId="a4b9c" Type="GeneProduct" GroupRef="afea2">
    <Comment Source="KeggConverter">Original kegg element: gene;168;mmu:100043714 mmu:100046796 mmu:20016 mmu:20017 mmu:20018 mmu:20019 mmu:20020 mmu:20021 mmu:20022 mmu:218832 mmu:231329 mmu:245841 mmu:26939 mmu:625405 mmu:64424 mmu:66136 mmu:66420 mmu:66491 mmu:67005 mmu:67065 mmu:67486 mmu:67710 mmu:69241 mmu:69833 mmu:69870 mmu:69920 mmu:70408 mmu:70428 mmu:74414 mmu:78929</Comment>
    <Graphics CenterX="3204.224130909176" CenterY="599.1702473823411" Width="90.94297214511298" Height="23.592612772064896" ZOrder="34563" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="67710" />
  </DataNode>
  <DataNode TextLabel="dITP" GraphId="d6c28" Type="Metabolite">
    <Graphics CenterX="985.6427783902974" CenterY="474.0655915385048" Width="80.0" Height="20.0" ZOrder="34564" FontSize="10" Valign="Middle" Color="0000ff" />
    <Xref Database="KEGG Compound" ID="C01345" />
  </DataNode>
  <DataNode TextLabel="5-hydroxyisourate" GraphId="c97e2" Type="Metabolite">
    <Graphics CenterX="1667.9999999999998" CenterY="1495.1639885538214" Width="110.65800865800844" Height="20.0" ZOrder="34565" FontSize="10" Valign="Middle" Color="0000ff" />
    <Xref Database="KEGG Compound" ID="C11821" />
  </DataNode>
  <DataNode TextLabel="Adcy10" GraphId="fea6d" Type="GeneProduct" GroupRef="e3f1d">
    <Comment Source="KeggConverter">Original kegg element: gene;166;mmu:104110 mmu:104111 mmu:11512 mmu:11513 mmu:11514 mmu:11515 mmu:210044 mmu:224129 mmu:271639 mmu:432530</Comment>
    <Graphics CenterX="3525.0385742900316" CenterY="722.0706628646263" Width="80.0" Height="20.0" ZOrder="34566" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="271639" />
  </DataNode>
  <DataNode TextLabel="Pde6b" GraphId="a2299" Type="GeneProduct" GroupRef="e4165">
    <Comment Source="KeggConverter">Original kegg element: gene;245;mmu:110385 mmu:110855 mmu:18573 mmu:18574 mmu:18575 mmu:18576 mmu:18577 mmu:18578 mmu:18582 mmu:18583 mmu:18584 mmu:18585 mmu:18587 mmu:18588 mmu:207728 mmu:218461 mmu:225600 mmu:238871 mmu:23984 mmu:241489 mmu:242202 mmu:29863 mmu:54611 mmu:78600</Comment>
    <Graphics CenterX="141.79898241873565" CenterY="883.8574623569881" Width="80.0" Height="20.0" ZOrder="34567" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="18587" />
  </DataNode>
  <DataNode TextLabel="Pde7b" GraphId="d3671" Type="GeneProduct" GroupRef="f5806">
    <Comment Source="KeggConverter">Original kegg element: gene;165;mmu:110385 mmu:18573 mmu:18574 mmu:18575 mmu:18576 mmu:18577 mmu:18578 mmu:18583 mmu:18584 mmu:207728 mmu:218461 mmu:238871 mmu:23984 mmu:241489 mmu:29863 mmu:54611</Comment>
    <Graphics CenterX="2713.2557883131203" CenterY="328.09536000597984" Width="80.0" Height="20.0" ZOrder="34568" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="29863" />
  </DataNode>
  <DataNode TextLabel="Polr3d" GraphId="b7a99" Type="GeneProduct" GroupRef="c746a">
    <Comment Source="KeggConverter">Original kegg element: gene;241;mmu:100043714 mmu:100046796 mmu:20016 mmu:20017 mmu:20018 mmu:20019 mmu:20020 mmu:20021 mmu:20022 mmu:218832 mmu:231329 mmu:245841 mmu:26939 mmu:625405 mmu:64424 mmu:66136 mmu:66420 mmu:66491 mmu:67005 mmu:67065 mmu:67486 mmu:67710 mmu:69241 mmu:69833 mmu:69870 mmu:69920 mmu:70408 mmu:70428 mmu:74414 mmu:78929</Comment>
    <Graphics CenterX="19.048068185003256" CenterY="1189.6132228177141" Width="92.46225755421057" Height="25.554043353358804" ZOrder="34569" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="67065" />
  </DataNode>
  <DataNode TextLabel="Papss1" GraphId="a9e93" Type="GeneProduct" GroupRef="e2a13">
    <Comment Source="KeggConverter">Original kegg element: gene;250;mmu:23971 mmu:23972</Comment>
    <Graphics CenterX="2933.519697934959" CenterY="267.4251263577146" Width="80.0" Height="20.0" ZOrder="34570" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="23971" />
  </DataNode>
  <DataNode TextLabel="Adcy6" GraphId="eede4" Type="GeneProduct" GroupRef="e3f1d">
    <Comment Source="KeggConverter">Original kegg element: gene;166;mmu:104110 mmu:104111 mmu:11512 mmu:11513 mmu:11514 mmu:11515 mmu:210044 mmu:224129 mmu:271639 mmu:432530</Comment>
    <Graphics CenterX="3525.0385742900316" CenterY="662.0706628646263" Width="80.0" Height="20.0" ZOrder="34571" FontSize="10" Valign="Middle" />
    <Xref Database="Entrez Gene" ID="11512" />
  </DataNode>
  <DataNode TextLabel="Atic" GraphId="db61d" Type="GeneProduct">
    <Comment Source="KeggConverter">Original kegg element: gene;159;mmu:108147</Comment>
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