<?xml version="1.0" encoding="UTF-8"?>
<Pathway xmlns="http://pathvisio.org/GPML/2013a" Name="Electron transport chain" Data-Source="WikiPathways" Version="WP295_r140438" Author="[Kdahlquist, MaintBot, M.Braymer, AlexanderPico, Christine Chichester, Khanspers, Egonw, Mkutmon, Papax, Fehrhart, Eweitz]" Last-Modified="20250823125728" Organism="Mus musculus">
  <Comment Source="WikiPathways-description">An electron transport chain(ETC) couples a chemical reaction between an electron donor (such as NADH) and an electron acceptor (such as O₂) to the transfer of H⁺ ions across a membrane, through a set of mediating biochemical reactions. These H⁺ ions are used to produce adenosine triphosphate (ATP), the main energy intermediate in living organisms, as they move back across the membrane. 
In mitochondria, it is the conversion of oxygen to water, NADH to NAD+ and succinate to fumarate that drives the transfer of H⁺ ions.
Source: [Wikipedia](https://en.wikipedia.org/wiki/Electron_transport_chain)</Comment>
  <Comment Source="HomologyMapper">This pathway was inferred from Homo sapiens pathway [http://wikipathways.org/instance/WP111_r95118 WP111 (r95118)] with a 94.0% conversion rate.</Comment>
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    <Comment Source="HomologyMapper">Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:498</Comment>
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  <DataNode TextLabel="Ndufb6" GraphId="a11" Type="GeneProduct" GroupRef="fd62f">
    <Comment Source="HomologyMapper">Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:4712</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="NDUFB6 | NADH dehydrogenase (ubiquinone) 1 beta..." />
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    <Xref Database="Ensembl" ID="ENSMUSG00000071014" />
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  <DataNode TextLabel="Atp5k" GraphId="a12" Type="GeneProduct" GroupRef="c0500">
    <Comment Source="HomologyMapper">Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:521</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="ATP5I | ATP synthase H+ transporting mitochon..." />
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    <Xref Database="Ensembl" ID="ENSMUSG00000050856" />
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  <DataNode TextLabel="Slc25a5" GraphId="a1d" Type="GeneProduct" GroupRef="e54f3">
    <Comment Source="HomologyMapper">Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:292</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="SLC25A5 | solute carrier family 25 (mitochondri..." />
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    <Xref Database="Ensembl" ID="ENSMUSG00000016319" />
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  <DataNode TextLabel="Cox15" GraphId="a31" Type="GeneProduct" GroupRef="fdd6a">
    <Comment Source="HomologyMapper">Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:1355</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="COX15 | COX15 homolog cytochrome c oxidase ass..." />
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    <Xref Database="Ensembl" ID="ENSMUSG00000040018" />
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  <DataNode TextLabel="Cox6b1" GraphId="a35" Type="GeneProduct" GroupRef="da9e9">
    <Comment Source="HomologyMapper">Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:1340</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="COX6B1 | cytochrome c oxidase subunit Vib polyp..." />
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  <DataNode TextLabel="Uqcr10" GraphId="a39" Type="GeneProduct" GroupRef="de99a">
    <Comment Source="HomologyMapper">Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:29796</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="UCRC | ubiquinol-cytochrome c reductase complex..." />
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  <DataNode TextLabel="Cox6c" GraphId="a4c" Type="GeneProduct" GroupRef="da9e9">
    <Comment Source="HomologyMapper">Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:1345</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="COX6C | cytochrome c oxidase subunit VIc" />
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    <Xref Database="Ensembl" ID="ENSMUSG00000014313" />
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  <DataNode TextLabel="Atp5j2" GraphId="a4e" Type="GeneProduct" GroupRef="c0500">
    <Comment Source="HomologyMapper">Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:9551</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="ATP5J2 | ATP synthase H+ transporting mitocho..." />
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    <Xref Database="Ensembl" ID="ENSMUSG00000038690" />
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  <DataNode TextLabel="Atp5o" GraphId="a5c" Type="GeneProduct" GroupRef="e472f">
    <Comment Source="HomologyMapper">Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:539</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="ATP5O | ATP synthase H+ transporting mitochon..." />
    <Graphics CenterX="1030.0" CenterY="380.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Ensembl" ID="ENSMUSG00000022956" />
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  <DataNode TextLabel="O₂" GraphId="a5e7d" Type="Metabolite">
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    <Xref Database="HMDB" ID="HMDB0001377" />
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  <DataNode TextLabel="Atp5g2" GraphId="a6e" Type="GeneProduct" GroupRef="c0500">
    <Comment Source="HomologyMapper">Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:517</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="ATP5G2 | ATP synthase H+ transporting mitocho..." />
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    <Xref Database="Ensembl" ID="ENSMUSG00000062683" />
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  <DataNode TextLabel="H⁺" GraphId="a7810" Type="Metabolite">
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    <Xref Database="ChEBI" ID="CHEBI:15378" />
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  <DataNode TextLabel="Ndufc1" GraphId="a80" Type="GeneProduct" GroupRef="fd62f">
    <Comment Source="HomologyMapper">Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:4717</Comment>
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  <DataNode TextLabel="Atp5b" GraphId="a92" Type="GeneProduct" GroupRef="cb58a">
    <Comment Source="HomologyMapper">Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:506</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="ATP5B | ATP synthase H+ transporting mitochon..." />
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    <Xref Database="Ensembl" ID="ENSMUSG00000025393" />
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  <DataNode TextLabel="Ndufa8" GraphId="a9b" Type="GeneProduct" GroupRef="fd62f">
    <Comment Source="HomologyMapper">Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:4702</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="NDUFA8 | NADH dehydrogenase (ubiquinone) 1 alph..." />
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    <Xref Database="Ensembl" ID="ENSMUSG00000026895" />
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  <DataNode TextLabel="ATP" GraphId="a9cb9" Type="Metabolite">
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    <Xref Database="KEGG Compound" ID="C00002" />
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  <DataNode TextLabel="Succinate" GraphId="ac151" Type="Metabolite">
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  <DataNode TextLabel="Uqcr11" GraphId="ad3" Type="GeneProduct" GroupRef="de99a">
    <Comment Source="HomologyMapper">Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:10975</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="UQCR | ubiquinol-cytochrome c reductase 6.4kDa..." />
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    <Xref Database="Ensembl" ID="ENSMUSG00000020163" />
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  <DataNode TextLabel="Ndufa3" GraphId="ae1" Type="GeneProduct" GroupRef="fd62f">
    <Comment Source="HomologyMapper">Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:4696</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="NDUFA3 | NADH dehydrogenase (ubiquinone) 1 alph..." />
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    <Xref Database="Ensembl" ID="ENSMUSG00000035674" />
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  <DataNode TextLabel="Slc25a14" GraphId="ae2" Type="GeneProduct" GroupRef="a6e66">
    <Comment Source="HomologyMapper">Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:9016</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="SLC25A14 | solute carrier family 25 (mitochondr..." />
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  <DataNode TextLabel="Ndufv2" GraphId="ae6" Type="GeneProduct" GroupRef="fd62f">
    <Comment Source="HomologyMapper">Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:4729</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="NDUFV2 | NADH dehydrogenase (ubiquinone) flavop..." />
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    <Xref Database="Ensembl" ID="ENSMUSG00000024099" />
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  <DataNode TextLabel="Ndufa6" GraphId="af0" Type="GeneProduct" GroupRef="fd62f">
    <Comment Source="HomologyMapper">Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:4700</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="NDUFA6 | NADH dehydrogenase (ubiquinone) 1 alph..." />
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    <Xref Database="Ensembl" ID="ENSMUSG00000022450" />
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  <DataNode TextLabel="mt-Co2" GraphId="af3" Type="GeneProduct" GroupRef="da9e9">
    <Comment Source="HomologyMapper">Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:4513</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="COX2 | cytochrome c oxidase subunit II" />
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    <Xref Database="Ensembl" ID="ENSMUSG00000064354" />
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  <DataNode TextLabel="Ndufb9" GraphId="af8" Type="GeneProduct" GroupRef="fd62f">
    <Comment Source="HomologyMapper">Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:4715</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="NDUFB9 | NADH dehydrogenase (ubiquinone) 1 beta..." />
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    <Xref Database="Ensembl" ID="ENSMUSG00000022354" />
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  <DataNode TextLabel="Ndufs6" GraphId="aff" Type="GeneProduct" GroupRef="fd62f">
    <Comment Source="HomologyMapper">Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:4726</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="NDUFS6 | NADH dehydrogenase (ubiquinone) Fe-S p..." />
    <Graphics CenterX="230.0" CenterY="373.3333333333333" Width="66.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Ensembl" ID="ENSMUSG00000021606" />
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  <DataNode TextLabel="Uqcrfs1" GraphId="b00" Type="GeneProduct" GroupRef="de99a">
    <Comment Source="HomologyMapper">Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:7386</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="UQCRFS1 | ubiquinol-cytochrome c reductase Rie..." />
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    <Xref Database="Ensembl" ID="ENSMUSG00000038462" />
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  <DataNode TextLabel="Ndufa2" GraphId="b0c" Type="GeneProduct" GroupRef="fd62f">
    <Comment Source="HomologyMapper">Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:4695</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="NDUFA2 | NADH dehydrogenase (ubiquinone) 1 alph..." />
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    <Xref Database="Ensembl" ID="ENSMUSG00000014294" />
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  <DataNode TextLabel="mt-Nd4l" GraphId="b21" Type="GeneProduct" GroupRef="fd62f">
    <Comment Source="HomologyMapper">Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:4539</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="ND4L | NADH dehydrogenase subunit 4L" />
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    <Xref Database="Ensembl" ID="ENSMUSG00000065947" />
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  <DataNode TextLabel="e-" GraphId="b29c4" Type="Metabolite">
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    <Xref Database="KEGG Compound" ID="C05359" />
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  <DataNode TextLabel="mt-Atp8" GraphId="b2b" Type="GeneProduct" GroupRef="c0500">
    <Comment Source="HomologyMapper">Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:4509</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="ATP8 | ATP synthase F0 subunit 8" />
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  <DataNode TextLabel="Ndufs5" GraphId="b39" Type="GeneProduct" GroupRef="fd62f">
    <Comment Source="HomologyMapper">Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:4725</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="NDUFS5 | NADH dehydrogenase (ubiquinone) Fe-S p..." />
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    <Xref Database="Ensembl" ID="ENSMUSG00000028648" />
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  <DataNode TextLabel="Cox5a" GraphId="b40" Type="GeneProduct" GroupRef="da9e9">
    <Comment Source="HomologyMapper">Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:9377</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="COX5A | cytochrome c oxidase subunit Va" />
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    <Xref Database="Ensembl" ID="ENSMUSG00000000088" />
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  <DataNode TextLabel="Uqcrc2" GraphId="b41" Type="GeneProduct" GroupRef="de99a">
    <Comment Source="HomologyMapper">Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:7385</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="UQCRC2 | ubiquinol-cytochrome c reductase core ..." />
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  <DataNode TextLabel="COX11" GraphId="b59" Type="GeneProduct" GroupRef="fdd6a">
    <Comment Source="HomologyMapper">Multiple homologues found: En:ENSMUSG00000020541;En:ENSMUSG00000020544;</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="COX11 | COX11 homolog cytochrome c oxidase ass..." />
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  <DataNode TextLabel="Atp5j" GraphId="b61" Type="GeneProduct" GroupRef="e472f">
    <Comment Source="HomologyMapper">Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:522</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="ATP5J | ATP synthase H+ transporting mitochon..." />
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    <Xref Database="Ensembl" ID="ENSMUSG00000022890" />
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  <DataNode TextLabel="Sdhb" GraphId="b62" Type="GeneProduct" GroupRef="d7381">
    <Comment Source="HomologyMapper">Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:6390</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="SDHB | succinate dehydrogenase complex subunit..." />
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    <Xref Database="Ensembl" ID="ENSMUSG00000009863" />
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  <DataNode TextLabel="mt-Co1" GraphId="b76" Type="GeneProduct" GroupRef="da9e9">
    <Comment Source="HomologyMapper">Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:4512</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="COX1 | cytochrome c oxidase subunit I" />
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    <Xref Database="Ensembl" ID="ENSMUSG00000064351" />
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  <DataNode TextLabel="FADH2" GraphId="b7f21" Type="Metabolite">
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    <Xref Database="KEGG Compound" ID="C01352" />
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  <DataNode TextLabel="Cox7a2l" GraphId="b87" Type="GeneProduct" GroupRef="da9e9">
    <Comment Source="HomologyMapper">Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:9167</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="COX7A2L | cytochrome c oxidase subunit VIIa pol..." />
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    <Xref Database="Ensembl" ID="ENSMUSG00000024248" />
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  <DataNode TextLabel="Ndufs7" GraphId="b8b" Type="GeneProduct" GroupRef="fd62f">
    <Comment Source="HomologyMapper">Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:374291</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="NDUFS7 | NADH dehydrogenase (ubiquinone) Fe-S p..." />
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    <Xref Database="Ensembl" ID="ENSMUSG00000020153" />
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  <DataNode TextLabel="Cox6a1" GraphId="b9c" Type="GeneProduct" GroupRef="da9e9">
    <Comment Source="HomologyMapper">Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:1337</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="COX6A1 | cytochrome c oxidase subunit VIa polyp..." />
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    <Xref Database="Ensembl" ID="ENSMUSG00000041697" />
  </DataNode>
  <DataNode TextLabel="Slc25a27" GraphId="bab" Type="GeneProduct" GroupRef="a6e66">
    <Comment Source="HomologyMapper">Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:9481</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="SLC25A27 | solute carrier family 25 member 27" />
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    <Xref Database="Ensembl" ID="ENSMUSG00000023912" />
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  <DataNode TextLabel="TCA Cycle" GraphId="bb20c" Type="Pathway">
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    <Xref Database="WikiPathways" ID="WP78" />
  </DataNode>
  <DataNode TextLabel="Ndufs4" GraphId="bbb" Type="GeneProduct" GroupRef="fd62f">
    <Comment Source="HomologyMapper">Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:4724</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="NDUFS4 | NADH dehydrogenase (ubiquinone) Fe-S p..." />
    <Graphics CenterX="230.0" CenterY="433.3333333333333" Width="66.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Ensembl" ID="ENSMUSG00000021764" />
  </DataNode>
  <DataNode TextLabel="Cox7a1" GraphId="bbf" Type="GeneProduct" GroupRef="da9e9">
    <Comment Source="HomologyMapper">Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:1346</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="COX7A1 | cytochrome c oxidase subunit VIIa poly..." />
    <Graphics CenterX="822.0" CenterY="473.3333333333333" Width="66.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Ensembl" ID="ENSMUSG00000074218" />
  </DataNode>
  <DataNode TextLabel="Cox4i1" GraphId="bc3" Type="GeneProduct" GroupRef="da9e9">
    <Comment Source="HomologyMapper">Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:1327</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="COX4I1 | cytochrome c oxidase subunit IV isofor..." />
    <Graphics CenterX="822.0" CenterY="293.3333333333333" Width="66.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Ensembl" ID="ENSMUSG00000031818" />
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  <DataNode TextLabel="H⁺" GraphId="bc4f2" Type="Metabolite">
    <Graphics CenterX="755.3333333333334" CenterY="96.0" Width="22.666666666666668" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" Color="0000ff" />
    <Xref Database="ChEBI" ID="CHEBI:15378" />
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  <DataNode TextLabel="COX7A3" GraphId="bd7" Type="GeneProduct" GroupRef="da9e9">
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="Cox7a-L-related" />
    <Graphics CenterX="822.0" CenterY="453.3333333333333" Width="66.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="" ID="" />
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  <DataNode TextLabel="H⁺" GraphId="bde98" Type="Metabolite">
    <Graphics CenterX="755.6666666666666" CenterY="338.0" Width="22.666666666666668" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" Color="0000ff" />
    <Xref Database="ChEBI" ID="CHEBI:15378" />
  </DataNode>
  <DataNode TextLabel="SLC25A6" GraphId="bea" Type="GeneProduct" GroupRef="e54f3">
    <Comment Source="HomologyMapper">No homologues found for original id L:293</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="SLC25A6 | solute carrier family 25 (mitochondri..." />
    <Graphics CenterX="1322.0" CenterY="273.3333333333333" Width="66.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="" ID="" />
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  <DataNode TextLabel="Atp5l" GraphId="c04" Type="GeneProduct" GroupRef="c0500">
    <Comment Source="HomologyMapper">Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:10632</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="ATP5L | ATP synthase H+ transporting mitochon..." />
    <Graphics CenterX="1030.0" CenterY="606.6666666666666" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Ensembl" ID="ENSMUSG00000038717" />
  </DataNode>
  <DataNode TextLabel="NDUFB1" GraphId="c12" Type="GeneProduct" GroupRef="fd62f">
    <Comment Source="HomologyMapper">No homologues found for original id L:4707</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="NDUFB1 | NADH dehydrogenase (ubiquinone) 1 beta..." />
    <Graphics CenterX="230.0" CenterY="253.33333333333334" Width="66.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="" ID="" />
  </DataNode>
  <DataNode TextLabel="Ucp3" GraphId="c2d" Type="GeneProduct" GroupRef="a6e66">
    <Comment Source="HomologyMapper">Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:7352</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="UCP3 | uncoupling protein 3 (mitochondrial pro..." />
    <Graphics CenterX="1191.3333333333333" CenterY="273.3333333333333" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Ensembl" ID="ENSMUSG00000032942" />
  </DataNode>
  <DataNode TextLabel="Uqcrh" GraphId="c54" Type="GeneProduct" GroupRef="de99a">
    <Comment Source="HomologyMapper">Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:7388</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="UQCRH | ubiquinol-cytochrome c reductase hinge ..." />
    <Graphics CenterX="658.6666666666666" CenterY="313.3333333333333" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Ensembl" ID="ENSMUSG00000063882" />
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  <DataNode TextLabel="FAD" GraphId="c57d6" Type="Metabolite">
    <Graphics CenterX="460.6666666666667" CenterY="376.0" Width="33.333333333333336" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" Color="0000ff" />
    <Xref Database="KEGG Compound" ID="C00016" />
  </DataNode>
  <DataNode TextLabel="Ndufa9" GraphId="c5a" Type="GeneProduct" GroupRef="fd62f">
    <Comment Source="HomologyMapper">Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:4704</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="NDUFA9 | NADH dehydrogenase (ubiquinone) 1 alph..." />
    <Graphics CenterX="230.0" CenterY="553.3333333333334" Width="66.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Ensembl" ID="ENSMUSG00000000399" />
  </DataNode>
  <DataNode TextLabel="H⁺" GraphId="c5b31" Type="Metabolite">
    <Graphics CenterX="584.0" CenterY="348.0" Width="22.666666666666668" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" Color="0000ff" />
    <Xref Database="ChEBI" ID="CHEBI:15378" />
  </DataNode>
  <DataNode TextLabel="Ndufb3" GraphId="c88" Type="GeneProduct" GroupRef="fd62f">
    <Comment Source="HomologyMapper">Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:4709</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="NDUFB3 | NADH dehydrogenase (ubiquinone) 1 beta..." />
    <Graphics CenterX="163.33333333333334" CenterY="413.3333333333333" Width="66.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Ensembl" ID="ENSMUSG00000026032" />
  </DataNode>
  <DataNode TextLabel="ATP5G1" GraphId="c96" Type="GeneProduct" GroupRef="c0500">
    <Comment Source="HomologyMapper">No homologues found for original id L:516</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="ATP5G1 | ATP synthase H+ transporting mitocho..." />
    <Graphics CenterX="1030.0" CenterY="480.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="" ID="" />
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  <DataNode TextLabel="Ndufb4" GraphId="c9a" Type="GeneProduct" GroupRef="fd62f">
    <Comment Source="HomologyMapper">Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:4710</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="NDUFB4 | NADH dehydrogenase (ubiquinone) 1 beta..." />
    <Graphics CenterX="163.33333333333334" CenterY="493.3333333333333" Width="66.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Ensembl" ID="ENSMUSG00000022820" />
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  <DataNode TextLabel="Cox7a2" GraphId="c9f" Type="GeneProduct" GroupRef="da9e9">
    <Comment Source="HomologyMapper">Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:1347</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="COX7A2 | cytochrome c oxidase subunit VIIa poly..." />
    <Graphics CenterX="822.0" CenterY="433.3333333333333" Width="66.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Ensembl" ID="ENSMUSG00000032330" />
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  <DataNode TextLabel="H⁺" GraphId="cabec" Type="Metabolite">
    <Graphics CenterX="1110.6666666666667" CenterY="460.6666666666667" Width="22.666666666666668" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" Color="0000ff" />
    <Xref Database="ChEBI" ID="CHEBI:15378" />
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  <DataNode TextLabel="mt-Nd6" GraphId="cac" Type="GeneProduct" GroupRef="fd62f">
    <Comment Source="HomologyMapper">Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:4541</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="ND6 | NADH dehydrogenase subunit 6" />
    <Graphics CenterX="163.33333333333334" CenterY="333.3333333333333" Width="66.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Ensembl" ID="ENSMUSG00000064368" />
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  <DataNode TextLabel="Atp5s" GraphId="cb0" Type="GeneProduct" GroupRef="c0500">
    <Comment Source="HomologyMapper">Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:27109</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="ATP5S | ATP synthase H+ transporting mitochon..." />
    <Graphics CenterX="1030.0" CenterY="653.3333333333334" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Ensembl" ID="ENSMUSG00000054894" />
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  <DataNode TextLabel="NAD+" GraphId="cb8fe" Type="Metabolite">
    <Graphics CenterX="38.666666666666664" CenterY="293.3333333333333" Width="37.333333333333336" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" Color="0000ff" />
    <Xref Database="KEGG Compound" ID="C00003" />
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  <DataNode TextLabel="Sdha" GraphId="cc7" Type="GeneProduct" GroupRef="d7381">
    <Comment Source="HomologyMapper">Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:6389</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="SDHA | succinate dehydrogenase complex subunit..." />
    <Graphics CenterX="365.3333333333333" CenterY="234.66666666666666" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Ensembl" ID="ENSMUSG00000021577" />
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  <DataNode TextLabel="H₂O" GraphId="ccb20" Type="Metabolite">
    <Graphics CenterX="936.6666748046875" CenterY="370.6666625976562" Width="32.016666666666666" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" Color="0000ff" />
    <Xref Database="HMDB" ID="HMDB0002111" />
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  <DataNode TextLabel="mt-Nd2" GraphId="cf6" Type="GeneProduct" GroupRef="fd62f">
    <Comment Source="HomologyMapper">Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:4536</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="ND2 | NADH dehydrogenase subunit 2" />
    <Graphics CenterX="163.33333333333334" CenterY="253.33333333333334" Width="66.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Ensembl" ID="ENSMUSG00000064345" />
  </DataNode>
  <DataNode TextLabel="Ndufab1" GraphId="d03" Type="GeneProduct" GroupRef="fd62f">
    <Comment Source="HomologyMapper">Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:4706</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="NDUFAB1 | NADH dehydrogenase (ubiquinone) 1 al..." />
    <Graphics CenterX="230.0" CenterY="353.3333333333333" Width="66.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Ensembl" ID="ENSMUSG00000030869" />
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  <DataNode TextLabel="Cox7b" GraphId="d07" Type="GeneProduct" GroupRef="da9e9">
    <Comment Source="HomologyMapper">Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:1349</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="COX7B | cytochrome c oxidase subunit VIIb" />
    <Graphics CenterX="822.0" CenterY="513.3333333333334" Width="66.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Ensembl" ID="ENSMUSG00000031231" />
  </DataNode>
  <DataNode TextLabel="Uqcrq" GraphId="d5d" Type="GeneProduct" GroupRef="de99a">
    <Comment Source="HomologyMapper">Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:27089</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="QP-C | low molecular mass ubiquinone-binding pr..." />
    <Graphics CenterX="658.6666666666666" CenterY="293.3333333333333" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Ensembl" ID="ENSMUSG00000044894" />
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  <DataNode TextLabel="Slc25a4" GraphId="d6c" Type="GeneProduct" GroupRef="e54f3">
    <Comment Source="HomologyMapper">Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:291</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="SLC25A4 | solute carrier family 25 (mitochondri..." />
    <Graphics CenterX="1322.0" CenterY="233.33333333333334" Width="66.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Ensembl" ID="ENSMUSG00000031633" />
  </DataNode>
  <DataNode TextLabel="Uqcrb" GraphId="d72" Type="GeneProduct" GroupRef="de99a">
    <Comment Source="HomologyMapper">Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:7381</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="UQCRB | ubiquinol-cytochrome c reductase bindin..." />
    <Graphics CenterX="658.6666666666666" CenterY="273.3333333333333" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Ensembl" ID="ENSMUSG00000021520" />
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  <DataNode TextLabel="mt-Nd5" GraphId="d89" Type="GeneProduct" GroupRef="fd62f">
    <Comment Source="HomologyMapper">Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:4540</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="ND5 | NADH dehydrogenase subunit 5" />
    <Graphics CenterX="163.33333333333334" CenterY="313.3333333333333" Width="66.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Ensembl" ID="ENSMUSG00000064367" />
  </DataNode>
  <DataNode TextLabel="Ndufa12" GraphId="d9a" Type="GeneProduct" GroupRef="fd62f">
    <Comment Source="HomologyMapper">Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:55967</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="DAP13 | 13kDa differentiation-associated protei..." />
    <Graphics CenterX="163.33333333333334" CenterY="533.3333333333334" Width="66.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Ensembl" ID="ENSMUSG00000020022" />
  </DataNode>
  <DataNode TextLabel="Sco1" GraphId="db2" Type="GeneProduct" GroupRef="fdd6a">
    <Comment Source="HomologyMapper">Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:6341</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="SCO1 | SCO cytochrome oxidase deficient homolog..." />
    <Graphics CenterX="820.6666666666666" CenterY="644.6666666666666" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Ensembl" ID="ENSMUSG00000069844" />
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  <DataNode TextLabel="Sdhd" GraphId="dbb" Type="GeneProduct" GroupRef="d7381">
    <Comment Source="HomologyMapper">Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:6392</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="SDHD | succinate dehydrogenase complex subunit..." />
    <Graphics CenterX="365.3333333333333" CenterY="294.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Ensembl" ID="ENSMUSG00000000171" />
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  <DataNode TextLabel="Atpif1" GraphId="ded" Type="GeneProduct" GroupRef="c0500">
    <Comment Source="HomologyMapper">Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:93974</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="ATPIF1 | ATPase inhibitory factor 1" />
    <Graphics CenterX="1030.0" CenterY="679.3333333333334" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Ensembl" ID="ENSMUSG00000054428" />
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  <DataNode TextLabel="Ndufb7" GraphId="df0" Type="GeneProduct" GroupRef="fd62f">
    <Comment Source="HomologyMapper">Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:4713</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="NDUFB7 | NADH dehydrogenase (ubiquinone) 1 beta..." />
    <Graphics CenterX="163.33333333333334" CenterY="553.3333333333334" Width="66.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Ensembl" ID="ENSMUSG00000033938" />
  </DataNode>
  <DataNode TextLabel="Ndufa1" GraphId="df1" Type="GeneProduct" GroupRef="fd62f">
    <Comment Source="HomologyMapper">Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:4694</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="NDUFA1 | NADH dehydrogenase (ubiquinone) 1 alph..." />
    <Graphics CenterX="230.0" CenterY="273.3333333333333" Width="66.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Ensembl" ID="ENSMUSG00000016427" />
  </DataNode>
  <DataNode TextLabel="Uqcrc1" GraphId="e02" Type="GeneProduct" GroupRef="de99a">
    <Comment Source="HomologyMapper">Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:7384</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="UQCRC1 | ubiquinol-cytochrome c reductase core ..." />
    <Graphics CenterX="658.6666666666666" CenterY="233.33333333333334" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Ensembl" ID="ENSMUSG00000025651" />
  </DataNode>
  <DataNode TextLabel="Ndufb5" GraphId="e03" Type="GeneProduct" GroupRef="fd62f">
    <Comment Source="HomologyMapper">Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:4711</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="NDUFB5 | NADH dehydrogenase (ubiquinone) 1 beta..." />
    <Graphics CenterX="230.0" CenterY="313.3333333333333" Width="66.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Ensembl" ID="ENSMUSG00000027673" />
  </DataNode>
  <DataNode TextLabel="Cox5b" GraphId="e04" Type="GeneProduct" GroupRef="da9e9">
    <Comment Source="HomologyMapper">Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:1329</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="COX5B | cytochrome c oxidase subunit Vb" />
    <Graphics CenterX="822.0" CenterY="333.3333333333333" Width="66.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Ensembl" ID="ENSMUSG00000061518" />
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  <DataNode TextLabel="H⁺" GraphId="e0eb0" Type="Metabolite">
    <Graphics CenterX="300.6666666666667" CenterY="66.66666666666667" Width="22.666666666666668" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" Color="0000ff" />
    <Xref Database="ChEBI" ID="CHEBI:15378" />
  </DataNode>
  <DataNode TextLabel="mt-Atp6" GraphId="e17" Type="GeneProduct" GroupRef="c0500">
    <Comment Source="HomologyMapper">Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:4508</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="ATP6 | ATP synthase F0 subunit 6" />
    <Graphics CenterX="1030.0" CenterY="433.3333333333333" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Ensembl" ID="ENSMUSG00000064357" />
  </DataNode>
  <DataNode TextLabel="mt-Co3" GraphId="e25" Type="GeneProduct" GroupRef="da9e9">
    <Comment Source="HomologyMapper">Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:4514</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="COX3 | cytochrome c oxidase subunit III" />
    <Graphics CenterX="822.0" CenterY="273.3333333333333" Width="66.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Ensembl" ID="ENSMUSG00000064358" />
  </DataNode>
  <DataNode TextLabel="Ndufs3" GraphId="e2a" Type="GeneProduct" GroupRef="fd62f">
    <Comment Source="HomologyMapper">Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:4722</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="NDUFS3 | NADH dehydrogenase (ubiquinone) Fe-S p..." />
    <Graphics CenterX="230.0" CenterY="533.3333333333334" Width="66.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Ensembl" ID="ENSMUSG00000005510" />
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  <DataNode TextLabel="Cox8a" GraphId="e3d" Type="GeneProduct" GroupRef="da9e9">
    <Comment Source="HomologyMapper">Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:1351</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="COX8A | cytochrome c oxidase subunit 8A (ubiqui..." />
    <Graphics CenterX="822.0" CenterY="553.3333333333334" Width="66.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Ensembl" ID="ENSMUSG00000035885" />
  </DataNode>
  <DataNode TextLabel="mt-Nd1" GraphId="e4e" Type="GeneProduct" GroupRef="fd62f">
    <Comment Source="HomologyMapper">Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:4535</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="ND1 | NADH dehydrogenase subunit 1" />
    <Graphics CenterX="163.33333333333334" CenterY="233.33333333333334" Width="66.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Ensembl" ID="ENSMUSG00000064341" />
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  <DataNode TextLabel="Ndufv1" GraphId="e6c" Type="GeneProduct" GroupRef="fd62f">
    <Comment Source="HomologyMapper">Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:4723</Comment>
    <Attribute Key="org.pathvisio.model.BackpageHead" Value="NDUFV1 | NADH dehydrogenase (ubiquinone) flavop..." />
    <Graphics CenterX="230.0" CenterY="613.3333333333334" Width="66.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
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